DE102006034320A1 - Antioxidant, useful for preparation of e.g. coloring agent, vesicle, dermocosmetic, pharmaceuticals and nutrient- or feedstuff, comprises at least an isorenieratene compound - Google Patents

Abstract

Antioxidant comprises at least an isorenieratene compound (I). Antioxidant comprises at least an isorenieratene compound of formula (I). R1>H or easily splittable protecting group; and R2>-R4>1-3C-alkyl. Independent claims are included for: (1) mixture (M1) comprising at least (I) and 3,3'-dihydroxyisorenieratene-1-quinone (II) and/or 3,3'-dihydroxy-2,2',4,4'-tetra-tert-butylisorenieratene-1-quinone (III); (2) mixture (M2) comprising 3,3'-dihydroxy-2,2',4,4'-tetra-tert-butylisorenieratene (IV) and at least (I) or (M1); (3) preparation (V) comprising (I), (II), (III) and/or (IV); (4) dermocosmetic, pharmaceutical and nutrient or feedstuff comprising (V); (5) solid material and/or liquid comprising (V); (6) coloring agent (A) comprising (II) or (III) or (IV) or (M1) or (M2); (7) coloring agent (B) comprising (V) in the form of H- or J-aggregate; (8) dermocosmetic, pharmaceutical, and nutrient or feedstuff comprising (A) or (B); (9) solid or liquid material comprising (A) or (B); (10) vesicle comprising (V); (11) dermocosmetic, pharmaceutical and nutrient- or feed stuff comprising the vesicle; (12) solid or liquid material comprising the vesicle; (13) carotenoid-formulation comprising (V); (14) preparation (VI)comprising the carotenoid formulation or (V); (15) dermocosmetic, pharmaceutical and nutrient or feedstuff comprising the carotenoids formulation or (V); (16) gelatin capsule comprising the carotenoids-formulation or (V); and (17) preparation of antioxidant, (M1) or (M2), (V), (A), vesicle, carotenoid-formulation, dermocosmetic, pharmaceutical, nutrient- or feedstuff, gelatin capsule or solid or liquid material comprising mixing (V), antioxidant, (M1) or (M2), (VI), (A), vesicle or carotenoid formulation. [Image].

Description

The The present invention relates to antioxidants, mixtures, preparations, dye, Vesicles, carotenoid formulations, dermocosmetics, pharmaceuticals, Food and feed and other solids or liquids or mixtures thereof, the 3,3'-dihydroxyisorenieratin, 3,3'-Dihydroxyisorenieratene-1-quinone, 3,3'-dihydroxy-2,2 ', 4,4'-tetra-tert-butylisorenieratin-1-quinone, 3,3'-dihydroxy-2,2 ', 4,4'-tetra-tert-butylisorenieratin or related isorenieratin compounds or using of these compounds or with a method that uses contains these compounds, were manufactured.

antioxidants Mixtures, preparations, colorants, Vesicles, carotenoid formulations, Dermocosmetics, pharmaceuticals, food and feed as well as other solids or liquids or mixtures thereof are complex mixtures of substances and show a high variability. It is therefore to be understood that the foregoing and the following yet to be explained Features of the subject invention not only in the specified special combination, but can also be used in other combinations, without the framework of To leave invention

carotenoids and other natural products have been used as dyes for some time and antioxidants as well as in dermocosmetics, food and feed used. In fact, many of the yellow to red colored carotenoids come as a natural product in starting products of food and feed in front.

Thus, carotenoids in colorants and carotenoid formulations can be used for human consumption. The font DE 198 02 134 A1 describes colorants from carotenoid aggregates. The font DE 198 38 636 A1 Carotenoid formulations from the combination of the carotenoids β-carotene, lycopene and lutein.

It It goes without saying that a wide range of application demands are high to the corresponding carotenoids, these often do not in the desired Comply with the scope can. Especially properties like availability, Stability, solubility and antioxidant effects of course Occurring carotenoids are often not sufficient to make it technically usable.

A previously used antioxidant carotenoid is astaxanthin. It is widely used as a dye with antioxidant effect in food and feed. Furthermore, there are research results showing the positive effects of astaxanthin on, for example, the immune system, kidneys, eyes, nerves, veins as well as diabetes, cancer, hypertension and a general anti-inflammatory effect ( Ghazi Nussein et al., Astaxanthin, a Carotenoid with Potential in Human Health and Nutrition, J. Nat. Prod. 2006, 69, 443-339 ).

An example of a synthetic carotenoid is the disuccinate derivative of astaxanthin, which is more soluble in an aqueous environment and can be used with positive effects in myocardial infarction ( Gross J., et al, Cardioprotection and myocardial salvage by a disodium disuccinate astaxanthin derivative (Cardax ™), Life Sciences 75, 2004, 215-224 ).

According to a scientific publication, the synthetic carotenoid 3,3'-dihydroxy-2,2 ', 4,4'-tetra-tert-butylisorenieratin (BHT carotenoid) has good antioxidant properties ( Beuter, S. et al., Modified flavonoids as photoprotecting UV absorbers and antioxidants, Advances in Color Science and Technology, 2002, 5, 103-112 ).

A technical use of this compound, in particular in dermocosmetics, Pharmaceuticals, food and feed and in particular in higher concentration was not revealed.

One of the objects of the present invention has been to find carotenoids which are versatile and widely applicable and readily available for technical applications. On the one hand, it was the task of providing well-tolerated carotenoids for humans and animals, which are not only used in dermocosmetics, food and animal feed and protect them against oxidative influences, but possibly also through their superior antioxidant activity and good health properties the health condition of humans and animals, by their use in dermocosmetics, food and feed prophylactically or therapeutically can positively influence. On the other hand, the object was to provide carotenoids available that can be used with good antioxidant activity in low concentrations and thereby offer the possibility of an undesirable color effect, especially for applications in the dermocosmetic or pharmaceutical sector, in food or feed or in Mixtures, preparations, vesicles, colorants or carotenoid formulations. On the other hand, it was another aspect of the task to achieve attractive color effects on the basis of these carotenoids, especially by means of this color effect, and to make this possible in particular with good compatibility for humans and animals. A further object was to provide carotenoids which, alone or in mixtures with other carotenoids, form aggregates with color-stabilizing or vesicle- or lipid-phase-stabilizing action and thus can be used advantageously in colorants, vesicles or other lipid phases.

3,3'-Dihydroxyisorenieratene, 3,3'-Dihydroxyisorenieratene-1-quinone, 3,3'-dihydroxy-2,2 ', 4,4'-tetra-tert-butylisorenieratin-1-quinone, 3,3'-dihydroxy-2,2 ', 4,4'-tetra-tert-butylisorenieratin or related, isorenieratin compounds, in particular 3,3'-dihydroxyisorenieratin solve the set tasks due to their surprisingly good and others Superior to carotenoids antioxidant properties. The resulting objects of the Invention will be described in the course of the invention disclosure.

worin
R¹ = H oder eine leicht abspaltbare Schutzgruppe oder Succinat bzw. dessen physiologisch verträglichen Salze sein kann,
R² bis R⁴ unabhängig voneinander gleich oder verschieden sein und eine C₁ bis C₃ Alkylgruppe sein kann.Isorenieratin compounds or compounds (I) are compounds of the general formula

wherein
R ¹ = H or an easily cleavable protecting group or succinate or its physiologically acceptable salts,
R ² to R ^{4 are} independently the same or different and may be a C ₁ to C ₃ alkyl group.

Light cleavable protecting groups are, for example, via ester compounds or Linked ether links and can from, for example, alkyl or alkene carboxylic acids, such as oleic acid or palmitate, or from acetylsalicylic acid or tocopherol.

3,3'-Dihydroxyisorenieratin is a compound of the formula:

3,3'-Dihydroxyisorenieratin-1-quinone or compound (II) is a compound of the formula:

3,3'-Dihydroxy-2,2 ', 4,4'-tetra-tert-butylisorenieratin-1-quinone or BHT-carotenoid quinone or compound (III) is a compound of the formula:

3,3'-Dihydroxy-2,2 ', 4,4'-tetra-tert-butylisorenieratin or BHT carotenoid or compound (IV) is a compound of the formula:

• – erfindungsgemäße Isorenieratin-Verbindungen bzw. Verbindungen (I) oder
• – 3,3'-Dihydroxyisorenieratin-1-quinon bzw. Verbindung (II) oder
• – 3,3'-Dihydroxy-2,2',4,4'-tetra-tert-butylisorenieratin-1-quinon bzw. Verbindung (III) oder
• – 3,3'-Dihydroxy-2,2',4,4'-tetra-tert-butylisorenieratin bzw. Verbindung (IV)

verstanden werden.Under compounds (V) is meant below

• Isorenieratin compounds of the invention or compounds (I) or
• - 3,3'-Dihydroxyisorenieratin-1-quinone or compound (II) or
• - 3,3'-dihydroxy-2,2 ', 4,4'-tetra-tert-butylisorenieratin-1-quinone or compound (III) or
• 3,3'-dihydroxy-2,2 ', 4,4'-tetra-tert-butylisorenieratin or compound (IV)

be understood.

carotenoids

carotenoids are tetraterpenes in which one or two ionon rings through a Carbon chain associated with 9 double bonds and both microbial, plant or animal origin or be prepared in a chemical synthesis. As carotenoids are also understood the oxygenated xanthophylls. exemplary include: alpha, beta, gamma-carotene, ixin, norbixin, capsanthin, Capsorubin, lycobin, beta-apo-8-carotenal, carotene acid ethyl ester as well as xanthophylls, flavoxanthin, lutein, cryptoaxanthin, Rubixanthin, Violaxanthin, Rhodoxanthin and Canthaxanthin. The above-mentioned compounds (V) fall into the class of carotinioids. Unless the above compounds (V) in addition to other carotenoids z. B. be present as a mixture component, these carotenoids merely other carotenoids mean the above compounds (V) do not include.

Dermocosmetics or dermocosmetics

"Dermocosmetics" or "dermocosmetics" describes dermocosmetic, hair cosmetic, dermatological or hygienic agents and / or formulations for topical application to skin or hair, suitable (i) for the prevention of damage to human skin and / or human hair, (ii) Treatment of already existing damage to the human skin and / or human hair, (iii) for the care of the human skin and / or human hair, (iv) for the improvement of the skin feeling (sensory properties). Explicitly included are perfumes and decorative cosmetics, such as kohl pencils, mascara, eyeshadows, tinted day creams, powders, concealers, blushes, lipsticks, lip pencils, makeup, nail polish or glamor gel. Also included are skin care compositions in which the pharmaceutically dermatological application is achieved taking into account cosmetic considerations. Such dermocosmetics are used for the support, prevention and treatment of skin diseases and can develop a biological effect in addition to the cosmetic effect. Be the dermocosmetics according to the invention are particularly preferably dermocosmetics for protecting the skin from damage by sunlight, in particular by UV-B (280 to 320 nm) and UV-A radiation (> 320 nm). Very particular preference is given to dermocosmetics containing the lipophilic vitamins A, D, E, K and their derivatives, preferably vitamin A or β-carotene. Dermocosmetics contain in a cosmetically acceptable medium suitable auxiliaries and additives, which are chosen with regard to the specific field of application. Such auxiliaries and additives are familiar to the expert and can, for. B. manuals of cosmetics, for example Schrader, bases and formulations of the cosmetics, Hüthig publishing house, Heidelberg, 1989, ISBN 3-7785-1491-1 , or Umbach, cosmetics: development, production and application of cosmetic products, 2nd extended edition, 1995, Georg Thieme Verlag, ISBN 3 13 712602 9 , are taken.

dermocosmetics suitable for protecting human skin or hair from UV radiation, contain one or more organic and / or inorganic light stabilizers or UV filters in combination with one or more of the following substances: emulsifiers, Surfactants, preservatives, perfume oils, thickeners, hair polymers, Hair and skin conditioners, graft polymers, water-soluble or dispersible silicone-containing polymers, gelling agents, care products, Tints, Tanning agents, Dyes, pigments, bodying agents, moisturizers, re-fats, Collagen, protein hydrolysates, lipids, and / or antioxidants.

"Dermo-cosmetic Active ingredients "or" dermocosmetic active ingredients "im The meaning of the present invention are those present in dermocosmetics Active substances which (i) for prevention of damage to the human skin and / or human hair, (ii) for treatment of already occurred damages human skin and / or human hair; (iii) care human skin and / or human hair, (iv) for improvement the skin feeling (sensory properties) and (iv) for decorative embellishment or Improving the appearance of human skin and / or human Hair is applied. Such agents are for. B. selected the group of natural or synthetic polymers, pigments, humectants, oils, waxes, Proteins, enzymes, minerals, vitamins, sunscreens, dyes, Fragrances, antioxidants, peroxide decomposers and preservatives and pharmaceutical agents for the support, prevention and treatment of skin diseases are used and a healing, damage preventive, regenerative or general condition of the skin have an improving biological effect.

suitable cosmetically and / or dermocosmetically active agents are, for. B. coloring Active ingredients, skin and hair pigmentation agents, toning agents, Tanning agents, Bleach, keratin-curing Substances, antimicrobial agents, light-filtering agents, repellents, hyperemic substances, keratolytic and keratoplastic active substances, anti-dandruff agents, antiphlogistics, keratinizing acting substances, antioxidant or radical scavengers active ingredients, skin moisturizing or moisturizing substances, moisturizing Active ingredients, antierythimatös or anti-allergic active ingredients, branched fatty acids such as 18-methyl eicosanoic acid, and Mixtures thereof.

As further dermocosmetic agents z. B. be used: acetylsalicylic acid, atropine, azulene, hydrocortisone and its derivatives, eg. As hydrocortisone 17-valerate, vitamins of the B and D series, especially vitamin B ₁ , vitamin B ₁₂ , vitamin D, vitamin A or its derivatives such as retinyl palmitate, vitamin E or its derivatives such. As tocopheryl acetate, vitamin C and its derivatives such. As ascorbyl glucoside but also niacinamide, panthenol, bisabolol, polydocanol, unsaturated fatty acids such. As the essential fatty acids (commonly referred to as vitamin F), in particular γ-linolenic acid, oleic acid, eicosapentaenoic acid, docosahexaenoic acid and its derivatives, chloramphenicol, caffeine, prostaglandins, thymol, camphor, squalene, extracts or other products of plant and animal origin , z. B. evening primrose oil, borage oil or blackcurrant seed oil, fish oils, cod liver oil but also ceramides and ceramide-like compounds, frankincense extract, water-lily extract, licorice extract, hamamelis, anti-dandruff active ingredients (eg selenium disulfide, zinc pyrithione, piroctone, olamine, climbazole, octopirox, polydocanol and their combinatines), Complex agents such. Those of γ-oryzanol and calcium salts such as calcium panthotenate, calcium chloride, calcium acetate. It is also advantageous to choose the dermocosmetic active ingredients from the group of refatting substances, for example PurCellin, Eucerit ^® and Neocerit® ^®. The active ingredient (s) are furthermore particularly advantageously selected from the group of NO synthase inhibitors, in particular when the preparations according to the invention are used for the treatment and prophylaxis of the symptoms of intrinsic and / or extrinsic skin aging and for the treatment and prophylaxis of the harmful effects of ultraviolet radiation on the skin and the Hair should serve. Preferred NO synthase inhibitor is nitroarginine. Also advantageous are the active ingredients selected from the group comprising catechins and bile acid esters of catechins and aqueous or organic extracts of plants or parts of plants which have a Content of catechins or bile acid esters of catechins. Also advantageous are their typical ingredients (eg polyphenols or catechins, caffeine, vitamins, sugars, minerals, amino acids, lipids). Catechins represent a group of compounds which are to be regarded as hydrogenated flavones or anthocyanidins and derivatives of "catechin" (catechol, 3,3 ', 4', 5,7-flavanpentaol, 2- (3,4-dihydroxyphenyl) -chroman Also, epicatechin ((2R, 3R) -3,3 ', 4', 5,7-flavanpentaol) is an advantageous active ingredient in the context of the present invention a content of catechins, in particular extracts of green tea, such as extracts from leaves of the plants of the species Camellia spec., Especially the teas Camellia sinenis, C. assamica, C. taliensis and C. inawadiensis and crosses of these with, for example, Camellia japonica.Preferred active substances are furthermore polyphenols or catechins from the group (-) - catechin, (+) - catechin, (-) - catechin gallate, (-) - gallocatechin gallate, (+) - epicatechin, (-) - Epicatechin, (-) - epicatechin gallate, (-) - epigallocatechin, (-) - epigallocatechin gallate.

"cosmetically compatible Medium "is wide to understand and means for the preparation of dermocosmetics suitable substances and mixtures the same.

"Substances that are cosmetically compatible" are all substances that generally do not cause any irritation or damage when they come into contact with human or animal skin tissue or hair, and are generally incompatible with other substances low allergenic potential and are approved by state approval authorities for use in cosmetic preparations These substances are familiar to the expert and can, for example, manuals of cosmetics, for example Schrader, bases and formulations of the cosmetics, Hüthig publishing house, Heidelberg, 1989, ISBN 3-7785-1491-1 , are taken.

flavones

wobei Z¹ bis Z⁹, unabhängig voneinander gewählt werden aus der Gruppe H, OH, Alkoxy- sowie Hydroxyalkoxy-, wobei die Alkoxy- bzw. Hydroxyalkoxygruppen verzweigt und unverzweigt sein und 1 bis 18 C-Atome aufweisen können. Z⁶ kann glykosyliert sein, wobei der entsprechende Rest aus der Gruppe der Mono- und Oligoglycosidreste ausgewählt ist.Flavones and their derivatives (often collectively called "flavones") are also advantageous dermocosmetic active substances in the context of the present invention. [Fl In] In nature, flavones are generally present in glycosylated form and are characterized by the following basic structure (substitution positions indicated):

where Z ¹ to Z ⁹ , independently of one another, are selected from the group consisting of H, OH, alkoxy and hydroxyalkoxy, where the alkoxy or hydroxyalkoxy groups may be branched and unbranched and have 1 to 18 C atoms. Z ⁶ can be glycosylated, the corresponding radical being selected from the group of mono- and oligoglycoside radicals.

Some of the more important flavones, which can also be used with preference in formulations according to the invention, have one or more substituents Z, for example one to six substituents Z, where Z can in particular be an OH group, as listed in Table 1 below. OH substitution positions Z ⁶ Z ⁷ Z ⁸ Z ⁹ Z ¹ Z ² Z ³ Z ⁴ Flavon - - - - - - - - flavonol + - - - - - - - Chrysin - + + - - - - - galangin + + + - - - - - apigenin - + + - - - + - fisetin + - + - - + + - luteolin - + + - - + + - kaempferol + + + - - - + - quercetin + + + - - + + - Morin + + + - + - + - robinetin + - + - - + + + gossypetin + + + + - + + - myricetin + + + - - + + + Table 1: Flavones

In addition, the dermocosmetic agents (one or more compounds) as well chosen very advantageous are selected from the group of hydrophilic agents, in particular following group: α-hydroxy acids such as lactic acid or salicylic acid or their salts such. B. Na-lactate, Ca-lactate, TEA-lactate, urea, Allantoin, serine, sorbitol, glycerin, milk proteins, panthenol, Chitosan.

Artificially skin-tanning dermocosmetic agents that are suitable for the skin without natural or artificial To irradiate irradiation with UV rays, z. B. dihydroxyacetone, Alloxan and walnut shell extract. Suitable keratin-hardening substances are usually dermocosmetic agents, as in antiperspirants be used, such as potassium aluminum sulfate, aluminum hydroxychloride, Aluminum lactate, etc.

peroxide decomposers:

As Peroxidzersetzer substances from different substance classes can be used. It goes without saying that for applications to humans and animals only substances are used, which usually have no adverse effect on health in the concentrations used. Substances suitable as peroxide decomposers may be sulfur-containing substances in which the sulfur is present in an oxidation state of less than +6. Phosphorus-containing compounds in which the phosphorus is present in an oxidation state of less than +5, as well as aromatic amines into consideration. The compounds containing sulfur and phosphorous may be of organic or inorganic nature, with substances of an organic nature being preferred. Whether certain compounds are suitable as Peroxidzersetzer, recognized in vitro, for example, that at room temperature, dissolved in a molar concentration of 0.05 m / l in a polar or non-polar solvent within 10 minutes, the peroxide or hydroperoxide concentration reduce by at least 20%, preferably 50% and in particular 90%. Substance classes containing peroxide decomposers are, for example: mercaptans, dialkyl, daryl or arylalkyl sulfides, dialkyl disulfides, dialkyl sulfoxides, sulfinic acids and their esters and amides, sulfenic acid esters or amides, thioesters, thioamides, thioureas, thiocarbonyl compounds, thioacetals or ketals also in cyclic form , Pyridine-2-thiol-3-carboxylic acid, 2-methoxy-pyrimidinol-carboxylic acids, 2-methoxy-pyridinecarboxylic acids, 2-dimethylamino-pyrimidinolcarboxylic acids, 2-dimethylaminopyridinecarboxylic acids. Further examples are in the writings WO0207698 and WO03059312 described.

Radical decomposer or radical scavenger:

Radical scavengers or scavengers are substances that can disrupt radical reaction chains by reacting with and neutralizing radicals. Such radicals are for example Hyroxyradikale, radical photoproducts or singlet oxygen. Substances which can be used as radical decomposers or radical scavengers are, for example, in DE 197 39 349 or in WO 2005/042828 described.

antioxidants

Antixodanites are substances that can protect other substances from oxidative reactions. As antioxidants, for example, amino acids (eg, glycine, histidine, tyrosine, tryptophan) and their derivatives, imidazoles (eg, urocanic acid) and their derivatives, peptides such as D, L-carnosine, D-carnosine, L-carnosine, and their derivatives (eg anserine), carotenoids, carotenes (eg α-carotene, β-carotene, lycopene) and their derivatives, chlorogenic acid and its derivatives, lipoic acid and its derivatives (eg dihydrolipoic acid), aurothioglucose , Propylthiouracil and other thiols (eg thioredoxin, glutathione, cysteine, cystine, cystamine and their glycosyl, N-acetyl, methyl, ethyl, propyl, amyl, butyl and lauryl, palmitoyl, oleyl , γ-linoleyl, cholesteryl and glyceryl esters) and their salts, dilauryl thiodipropionate, distearyl thiodipropionate, thiodipropionic acid and derivatives thereof (esters, ethers, peptides, lipids, nucleotides, nucleosides and salts) and sulfoximine compounds (eg buthionine sulfoximines, homocysteinesulfoximine, Buthione sulfones, penta-, hexa-, heptathionine sul foximin) in very low tolerated dosages (e.g. Pmol to μmol / kg), furthermore (metal) chelators (eg α-hydroxyfatty acids, palmitic acid, phytic acid, lactoferrin), α-hydroxy acids (eg citric acid, lactic acid, malic acid), humic acid, bile acid, Bile extracts, bilirubin, biliverdin, EDTA, EGTA and their derivatives, unsaturated fatty acids and their derivatives (eg γ-linolenic acid, linoleic acid, oleic acid), folic acid and its derivatives, furfurylidene sorbitol and its derivatives, ubiquinone and ubiquinol and their derivatives, vitamin C and derivatives (eg, ascorbyl palmitate, Mg ascorbyl phosphate, ascorbyl acetate), tocopherols and derivatives (eg, vitamin E acetate), vitamin A and derivatives (vitamin A palmitate), and benzylic benzoate, rutinic acid, and benzylic acid their derivatives, α-glycosylrutin, ferulic acid, furfurylidene glucitol, carnosine, butylhydroxytoluene, butylhydroxyanisole, nordihydroguaiacetic acid, nordihydroguaiaretic acid, trihydroxybutyrophenone, uric acid and its derivatives, mannose and its derivatives, zinc and its derivatives (e.g., ZnO, ZnSO ₄ ), selenium and its derivatives (e.g. Selenium methionine), stilbenes and their derivatives (eg stilbene oxide, trans-stilbene oxide). The compounds (V) can be used as antioxidants. When the above-mentioned compounds (V) are used besides antioxidants, these antioxidants are merely meant to mean further antioxidants which do not include the above-mentioned compounds (V).

Antimicrobial agents

antimicrobial Active ingredients are used to destroy microorganisms or inhibit their growth and can thus both as a preservative and as a deodorant acting substance, which determines the formation or intensity of body odor reduced. As antimicrobial agents and preservatives can for example, usual, known to the expert antimicrobial agents and preservatives, such as p-hydroxybenzoic acid ester, Imidazolidinyl urea, formaldehyde, sorbic acid, benzoic acid, salicylic acid, etc. Such deodorizing substances are z. B. zinc ricinoleate, Triclosan, undecylenic acid alkylolamides, triethyl citrate, Chlorhexidine be used.

Further suitable antimicrobial agents are: E 200 sorbic acid E 227 calcium bisulfite E 201 sodium sorbate E 228 potassium hydrogen sulfite) E 202 potassium sorbate E 230 Biphenyl (diphenyl) E 203 calcium sorbate E 231 orthophenylphenol E 210 benzoic acid E 232 sodium orthophenylphenolate E 211 sodium benzoate E 233 thiabendazole E 212 potassium benzoate E 235 natamycin E 213 calcium benzoate E 236 formic acid E 214 p-hydroxybenzoic acid ethyl ester E 237 sodium E 215 p-Hydroxybenzoesäureethyl-ester sodium salt E 238 calcium E 216 p-hydroxybenzoic acid n-propyl ester E 239 hexamethylenetetramine E 217 p-hydroxybenzoic acid n-propyl ester sodium salt E 249 potassium nitrite E 218 p-hydroxybenzoate E 250 sodium nitrite E 219 p-hydroxybenzoic acid methyl ester sodium salt E 251 sodium nitrate E 220 sulfur dioxide E 252 potassium nitrate E 221 sodium E 280 propionic E 222 Natriumyhdrogensulfit E 281 sodium propionate E 223 sodium metabisulfite E 282 calcium propionate E 224 called potassium E 283 Potassium E 226 calcium sulfite E 290 carbon dioxide Table 2: suitable antimicrobial agents. The E numbers listed in the above table are the common names in Directive 95/2 / EEC.

Other antimicrobial agents and preservatives are also suitable, in particular, they are suitable to be incorporated into the dermocosmetics and pharmaceuticals according to the invention. Advantageous substances are, for example, 2,4,4'-trichloro-2'-hydroxydiphenyl ether (Irgasan), 1,6-di- (4-chlorophenylbiguanido) hexane (chlorhexidine), 3,4,4'-trichlorocarbanilide, quaternary ammonium compounds , Clove oil, mint oil, thyme oil, triethyl citrate, farnesol (3,7,11-trimethyl-2,6,10-dodecatrien-1-ol) and those disclosed in the patent publications DE-37 40 186 . DE-39 38 140 . DE-42 04 321 . DE-42 29 707 . DE-43 09 372 . DE-44 11 664 . DE-195 41 967 . DE-195 43 695 . DE-195 43 696 . DE-195 47 160 . DE-196 02 108 . DE-196 02 110 . DE-196 02 111 . DE-196 31 003 . DE-196 31 004 and DE-196 34 019 and the patents DE-42 29 737 . DE-42 37 081 . DE-43 24 219 . DE-44 29 467 . DE-44 23 410 and DE-195 16 705 described active ingredients or drug combinations. Also, sodium bicarbonate is advantageous to use. Likewise, microbial polypeptides can be used. Others are:
Dibromodicyanobutane (2-bromo-2-bromomethyl-glutarodinitrile), 3-iodo-2-propynyl butyl carbamate, 2-bromo-2-nitro-propane-1,3-diol, imidazolidinyl urea, 5-chloro-2-methyl-4-isothiazoline -3-one, 2-chloroacetamide, benzalkonium chloride and benzyl alcohol suitable. Further, phenylhydroxyalkyl ethers, especially the compound known as phenoxyethanol, are useful as antimicrobial agents and preservatives because of their bactericidal and fungicidal effects on a number of microorganisms.

perfume oils

-Hexylzimtaldehyd, Geraniol, Benzylaceton, Cyclamenaldehyd, Linalool, Boisambrene^®Forte, Ambroxan, Indol, Hedione, Sandelice, Citronenöl, Mandarinenöl, Orangenöl, Allylamylglycolat, Cyclovertal, Lavandinöl, Muskateller Salbeiöl,

-Damascone, Geraniumöl Bourbon, Cyclohexylsalicylat, Vertofix^®Coeur, Iso-E-Super^®, Fixolide^®NP, Evernyl, Iraldein gamma, Phenylessigsäure, Geranylacetat, Benzylacetat, Rosenoxid, Romillat, Irotyl und Floramat allein oder in Mischungen eingesetztPerfume oils are, for example, mixtures of natural and synthetic fragrances, which are used, for example, in perfumes. Natural fragrances are extracts of flowers (lily, lavender, rose, jasmine, neroli, ylang-ylang), stems and leaves (geranium, patchouli, petitgrain), fruits (aniseed, coriander, caraway, juniper), fruit peel (bergamot, lemon, Orange), Roots (Macis, Angelics, Celery, Cardamom, Costus, Iris, Calmus), Woods (Pine, Sandal, Guajac, Cedar, Rosewood), Herbs and Grasses (Tarragon, Lemongrass, Sage, Thyme), Needles and twigs (spruce, fir, pine, pines), resins and balsams (galbanum, elemi, benzoin, myrrh, olibanum, opoponax). Furthermore, animal raw materials come into consideration, such as civet and Castoreum. Typical synthetic fragrance compounds are ester type products, ethers, aldehydes, ketones, alcohols and hydrocarbons. Fragrance compounds of the ester type are e.g. Benzyl acetate, phenoxyethyl isobutyrate, 4-tert-butylcyclohexyl acetate, linalyl acetate, dimethylbenzylcarbinylacetate, phenylethylacetate, linalylbenzoate, benzylformate, ethylmethylphenylglycinate, allylcyclohexylpropionate, styrallylpropionate and benzylsalicylate. The ethers include, for example, benzyl ethyl ether to the aldehydes z. For example, the alkanals having 8 to 18 carbon atoms, citral, citronellal, citronellyloxyacetaldehyde, cyclamen aldehyde, hydroxycitronellal, lilial and bourgeonate, to the ketones ZB the ionones, cc-isomethyl ions and methyl cedryl ketone, to the alcohols anethole, citronellol, eugenol, isoeugenol, geraniol, Linalool, phenylethyl alcohol and terioneol, the hydrocarbons include mainly the terpenes and balsams. Preferably, however, mixtures of different fragrances are used, which together produce an attractive fragrance. Also essential oils of lower volatility, which are mostly used as aroma components, are suitable as perfume oils, for example sage oil, chamomile oil, clove oil, lemon balm oil, mint oil, cinnamon oil, lime blossom oil, juniper berry oil, vetiver oil, oliban oil, galbanum oil, labolanum oil and lavandin oil. Preferably, bergamot oil, dihydromyrcenol, lilial, lyral, citronellol, phenylethyl alcohol,

-Hexylzimtaldehyd, geraniol, benzyl acetone, cyclamen aldehyde, linalool, Boisambrene Forte ^®, Ambroxan, indole, hedione, Sandelice, lemon oil, mandarin oil, orange oil, allyl amyl glycolate, Cyclovertal, lavandin oil, muscatel sage oil,

-Damascone, geranium oil bourbon, cyclohexyl salicylate, Vertofix ^® Coeur, Iso-E-Super ^{®, ®} Fixolide NP, Evernyl, Iraldein gamma, phenylacetic acid, geranyl acetate, benzyl acetate, rose oxide, romillat, irotyl and floramat alone or in mixtures

flavors

flavors are mixtures of odors or flavorings (flavorings) which are especially intended to give food a special To give smell or taste. Flavors can be in addition to a variety of Flavored substances include, for example, solvents, Carriers, preservatives and antioxidants. Flavorings may be natural Flavored, nature-identical flavors, artificial flavors, aroma extracts, Reaction flavors and smoke flavors exist. Preferred flavorings are natural Flavorings, nature-identical flavors and artificial flavors. flavorings can be biochemically synthesized or fully synthetic and free or bound as glycoside (bound flavorings) are present. flavorings usually fall into the group of alcohols, aldehydes u. Ketones, esters, Lactones, sulfides and the like Heterocycles, e.g. Furan verb, pyrazines, thiazoles or thiophenes terpenes, sesquiterpenes, thiols, sulphides, di-, tri-, Tetra u. Pentasulfides, trithiolanes, thioesters, alkenals, glucosinolates or Isothiocyanates. examples for Flavorings are: α-ionone, β-ionone, γ-ionone, 2-acetyl-1-pyrroline, (2E, 42) -decadienoic acid, Bis (2-methyl-3-furyl) disulphide, 2-methyl-3- (methylthio) furan, (+) - nootkatone, (+) - (S) -carvone, (+) - (R) -p-menth-1-en-8-thiol, Cital, Neral, Geranial Citronellal, Vanillin biacetyl, maltol, 2-methoxy-3-isobutylpyrazine, 4- (4-hydroxyphenyl) -2-butanone, butyric acid, methyl ketones, Ethyl acetate, acetoin, Butane-2,3-dione, γ-dexalactone, γ-lactones 3-ethyl-5-methyl-1,2,4-trithiolane, 1,2-dithiolane-4-carboxylic acid, 1,2-dithiolane-4-carboxylic acid methyl ester, 1,2-dithiacyclopentene, 2-propionioic acid S-methyl ester, 3- (methylthio) thiopropionic acid S-methyl ester, 1-Penten-3-one, 1-nitro-2-phenylethane 2-alkyl-3-methoxypyrazines, (2-isopropylpyrazine, 2-isobutylpyrazine, Of 2-sec-Butyl-pyrazine, (E) -2-nonenal, (E, Z) -2,6-nonadienal, (E, E) -2,4-decadienal, hexan-1-ol and the like. (Z) -3-hexen-1-ol, (E, Z) -2,6-nonadienal, (E) - u. (Z) -2-nonenal, (Z) -1,5-octadien-3-one 2-isopropyl-3-methoxypyrazine, 2,5-dimethylpyrazine, 2-ethyl-3,6-dimethylpyrazine, (E) -2-nonenal, (E) -2-decenal, (E, E) -2,4-decadienal, 2-sec-butyl-3-methoxypyrazine, (E, Z) -2,6-nonadienal, (E, E) -2,4-decadienal, 2-alkyl-3-methoxypyrazine, 3-ethyl-5-methyl-1,2,4-trithiolane, 1,2-dithiolane-4-carboxylic acid 1,2-dithiacyclopentene, 2-acetylthiazole, Geosmin, hexanal, (Z) -3-hexenal, (E) -2-hexenal, hexanal, β-damascenone, 1-penten-3-one, 3-methylbutanal, 2-isobutylthiazole, dimethylsulfide, 1-nitro-2-phenylethane, Eugenol, methional, 3-methylbutyric acid (E, Z) -2,6-nonadienal, (-) - (R) -carvone, (-) - (R) -1-Octene-3-ol, (-) - (R) -1-Octene-3-ol, Benzaldehyde, p-anisaldehyde, 2-aminobenzaldehyde, methyl anthranilate, 1,3-dimethoxybenzene, coumarin, herniarine, limettin

oils Fats and waxes

As oils, fats and waxes may be used, for example: hydrocarbon oils such as paraffin oil, purcellin oil, perhydrosqualene and solutions of microcrystalline waxes in these oils; animal or vegetable oils, such as sweet almond oil, avocado oil, Calophylumöl, lanolin and derivatives thereof, castor oil, sesame oil, olive oil, jojoba oil, karite oil, Hoplostethus oil, mineral oils whose distillation begins under atmospheric pressure at about 250 ° C and their distillation endpoint at 410 ° C is such. As Vaselineöl, esters of saturated or unsaturated fatty acids, such as alkyl myristates, z. I-propyl, butyl or cetyl myristate, hexadecyl stearate, ethyl or i-propyl palmitate, octanoic or decanoic acid triglycerides and cetyl ricinoleate or other oil-soluble silicone oils such as dimethylpolysiloxane, methylphenylpolysiloxane and the silicone glycol copolymer, fatty acids and fatty alcohols, fatty ketones, Fatty aldehydes, fatty ethers and fatty carbonates, for example, lauron and distearyl ethers or fatty acids, such as stearic acid, hydroxystearic acid or behenic acid, ring-opening products of olefin epoxides with C ₁₂ -C ₂₂ carbon atoms with fatty alcohols with C ₁₂ -C ₂₂ carbon atoms and / or polyols with C ₂ -C ₁₅ carbon atoms and C ₂ -C ₁₀ hydroxyl groups and mixtures thereof.

When Waxes can For example, carnauba wax, candililla wax, Beeswax, microcrystalline wax, ozokerite wax and Ca, Mg and Al-Oleate, myristates, Be linoleates and stearates.

Oils, fats and waxes are furthermore advantageously selected from the group of lecithins and fatty acid triglycerides, namely the triglycerol esters of saturated and / or unsaturated, branched and / or unbranched alkanecarboxylic acids having a chain length of C ₈ -C ₂₄ , in particular C ₁₂ -C ₁₈ C- atoms. The fatty acid triglycerides can be selected, for example, advantageously from the group of synthetic, semi-synthetic and natural oils, such as. Olive oil, sunflower oil, soybean oil, peanut oil, rapeseed oil, almond oil, palm oil, coconut oil, castor oil, wheat germ oil, grapeseed oil, thistle oil, evening primrose oil, macadamia nut oil and the like. Other polar oil components can be selected from the group of esters of saturated and / or unsaturated, branched and / or unbranched alkanecarboxylic acids having a chain length of C ₃ -C ₃₀ C atoms and saturated and / or unsaturated, branched and / or unbranched alcohols of one chain length of C ₃ -C ₃₀ C atoms and from the group of esters of aromatic Carbonsäu ren and saturated and / or unsaturated, branched and / or unbranched alcohols of a chain length of C ₃ -C ₃₀ C atoms. Such ester oils can then advantageously be selected from the group isopropyl myristate, isopropyl palmitate, isopropyl stearate, isopropyl oleate, n-butyl stearate, n-hexyl laurate, n-decyl oleate, isooctyl stearate, isononyl stearate, isononyl isononanoate, 2-ethylhexyl palmitate, 2-ethylhexyl laurate, 2-hexyldecyl stearate, 2-octyl-dodecyl palmitate, oleyl oleate, oleyl erucate, erucyl oleate, erucyl erucate dicaprylyl carbonate (Cetiol CC) and cocoglycerides (Myritol 331), butylene glycol dicaprylate / dicaprate and dibutyl adipate, and synthetic, semi-synthetic and natural mixtures of such esters, such as e.g. B. jojoba oil.

Furthermore, one or more oil or wax components can be advantageously selected from the group of branched and unbranched hydrocarbons and waxes, the silicone oils, the dialkyl ethers, the group of saturated or unsaturated, branched or unbranched alcohols. Any mixtures of such oil or wax components are advantageous to use in the context of the present invention. It may also be advantageous, if appropriate, to use waxes, for example cetyl palmitate, as the sole lipid component of the oil phase. According to the invention, one or more oil or wax components are advantageously selected from the group consisting of 2-ethylhexyl isostearate, octyldodecanol, isotridecyl isononanoate, isoeicosane, 2-ethylhexyl cocoate, C ₁₂ -C ₁₅ -alkyl benzoate, caprylic-capric triglyceride, dicaprylyl ether.

Mixtures of C ₁₂ -C ₁₅ -alkyl benzoate and 2-ethylhexyl isostearate, mixtures of C ₁₂ -C ₁₅ -alkyl benzoate and isotridecyl isononanoate and mixtures of C ₁₂ -C ₁₅ -alkyl benzoate, 2-ethylhexyl isostearate and isotridecyl isononanoate are advantageous according to the invention. Particular preference is given according to the invention to fatty acids triglycerides, in particular soybean oil and / or almond oil, as oils having a polarity of from 5 to 50 mN / m. Of the hydrocarbons, paraffin oil, squalane and squalene are to be used advantageously in the context of the present invention.

durch Oxidation eines Alkohols zu einem Aldehyd, durch Aldol-Kondensation des Aldehyds, Abspaltung von Wasser aus dem Aldol- und Hydrierung des Allylaldehyds. Guerbetalkohole sind selbst bei niederen Temperaturen flüssig und bewirken praktisch keine Hautreizungen. Vorteilhaft können sie als fettende, überfettende und auch rückfettend wirkende Bestandteile in kosmetischen Zusammensetzungen eingesetzt werden.Furthermore, one or more oil or wax components can be advantageously selected from the group of Guerbet alcohols. Guerbet alcohols are named after Marcel Guerbet, who first described their production. They arise according to the reaction equation

by oxidation of an alcohol to an aldehyde, by aldol condensation of the aldehyde, elimination of water from the aldol and hydrogenation of allyl aldehyde. Guerbet alcohols are fluid even at low temperatures and cause virtually no skin irritation. Advantageously, they can be used as greasing, overfatting and also moisturizing ingredients in cosmetic compositions.

aus. Dabei bedeuten R⁵ und R⁶ in der Regel unverzweigte Alkylreste.The use of Guerbet alcohols in cosmetics is known per se. Such species are usually characterized by the structure

out. R ⁵ and R ^{6 are} generally unbranched alkyl radicals.

Advantageously according to the invention, the Guerbet alcohol or alcohols are selected from the group, where
R ⁵ = propyl, butyl, pentyl, hexyl, heptyl or octyl and
R ⁶ = hexyl, heptyl, octyl, nonyl, decyl, undecyl, dodecyl, tridecyl or tetradecyl.

According to the invention preferred Guerbet alcohols are 2-butyl (for example as Isofol ^® 12 (Condea) commercially available) and 2-hexyl decanol (for example as Isofol ^® 16 (Condea) commercially available). Also, mixtures of Guerbet alcohols are according to the invention may advantageously be used such as mixtures of 2-butyloctanol and 2-hexyl decanol (for example as Isofol ^® 14 (Condea) commercially available).

Also any mixtures of such oil or wax components are advantageous in the sense of the present Use invention. Among the polyolefins, polydecenes are preferred substances.

Advantageously, the oil or wax component may also contain or consist entirely of cyclic or linear silicone oils, although it is preferred to use an additional content of other oil or wax components in addition to the silicone oil or silicone oils. Low molecular weight silicones or silicone oils are generally defined by the following general formula:

wobei die Siliciumatome mit gleichen oder unterschiedlichen Alkylresten und/oder Arylresten substituiert sein können, welche hier verallgemeinernd durch die Reste R⁷ bis R¹⁰ dargestellt sind. Die Anzahl der unterschiedlichen Reste ist aber nicht notwendigerweise auf bis zu 4 beschränkt. Man kann dabei Werte von 2 bis 200.000 annehmen.Higher molecular weight silicones or silicone oils are generally defined by the following general formula

wherein the silicon atoms may be substituted with identical or different alkyl radicals and / or aryl radicals, which are here generalized by the radicals R ⁷ to R ¹⁰ . However, the number of different residues is not necessarily limited to 4. You can choose values from 2 to 200,000 accept.

wobei die Siliciumatome mit gleichen oder unterschiedlichen Alkylresten und/oder Arylresten substituiert werden können, welche hier verallgemeinernd durch die Reste R⁷ bis R¹⁰ dargestellt sind. Die Anzahl der unterschiedlichen Reste ist aber nicht notwendigerweise auf bis zu 4 beschränkt. "n" kann dabei Werte von 3/2 bis 20 annehmen. Gebrochene Werte für n berücksichtigen, daß ungeradzahlige Anzahlen von Siloxylgruppen im Zyklus vorhanden sein können.Cyclic silicones which are advantageously used in accordance with the invention are generally defined by the following general formula

wherein the silicon atoms can be substituted with identical or different alkyl radicals and / or aryl radicals, which are here generalized by the radicals R ⁷ to R ¹⁰ . However, the number of different residues is not necessarily limited to 4. "n" can assume values of 3/2 to 20. Broken values for n take into account that odd numbers of siloxyl groups may be present in the cycle.

Advantageous Phenyltrimethicone is chosen as the silicone oil. Also other silicone oils, for example Dimethicone, hexamethylcyclotrisiloxane, phenyldimethicone, cyclomethicone (Octamethylcyclotetrasiloxane), hexamethylcyclotrisiloxane, polydimethylsiloxane, Poly (methylphenylsiloxane), cetyl dimethicone, behenoxydimethicone advantageous to use in the context of the present invention. Advantageous are also mixtures of cyclomethicone and isotridecyl isononanoate, and those of cyclomethicone and 2-ethylhexyl isostearate. It is also advantageous, silicone oils more similar Constitution as the compounds referred to above, whose derivatized organic side chains, for example polyethoxylated and / or polypropoxylated. These include, for example, polysiloxane polyalkyl-polyether copolymers such as B. cetyl dimethicone copolyol. Advantageous Cyclomethicone (Octamethylcyclo-tetrasiloxane) is used as the invention silicone oil used. Further advantageous to use fats and / or Waxes can from the group of vegetable waxes, animal waxes, mineral waxes and petrochemical waxes become. For example, candelilla wax, carnauba wax, Japan wax, esparto wax, cork wax, guaruma wax, rice germ oil wax, Sugar cane wax, berry wax, ouricury wax, montan wax, jojoba wax, Shea butter, beeswax, shellac wax, spermaceti, lanolin (wool wax), uropygial fat, Ceresin, ozokerite (earth wax), paraffin waxes and microwaxes.

Further advantageous Fette and / or waxes are chemically modified waxes and synthetic waxes, such as Syncrowax HRC ^® (glyceryl tribehenate), and Syncrowax ^® AW 1 C (C ₁₈ -C ₃₆ fatty acid) as well as Montanesterwachse, sasol waxes, hydrogenated jojoba waxes, synthetic or modified beeswaxes (z. B. dimethicone copolyol beeswax and / or C ₃₀ -C ₅₀ alkyl beeswax), Cetyl Ricinoleate such as Tegosoft ^® CR, polyalkylene waxes, polyethylene glycol waxes, but also chemically modified fats such. Hydrogenated coconut oil glyceride, trihydroxystearin, fatty acids, fatty acid esters and glycol esters such as C ₂₀ -C ₄₀ alkyl stearate, C ₂₀ -C ₄₀ alkyl hydroxy stearate stearate and / or hydrogenated vegetable oils (for example hydrogenated castor oil and / or hydrogenated coconut fat glycerides). or glycol montanate. Also advantageous are certain organosilicon compounds which have similar physical properties to the fatty and / or wax components mentioned, such as, for example, stearoxytrimethylsilane.

The fats and / or waxes can be used both individually and as a mixture in the compositions. Any mixtures of such oil and wax components are also advantageous to use in the context of the present invention. Advantageously, the oil phase is selected from the group consisting of 2-ethylhexyl isostearate, octyldodecanol, isotridecyl isononanoate, butylene glycol dicaprylate / dicaprate, 2-ethylhexyl cocoate, C _12-15 alkyl benzoate, caprylic capric acid triglyceride, dicaprylyl ether. Particularly advantageous are mixtures of octyldodecanol, caprylic-capric triglyceride, dicaprylyl ether, dicaprylyl carbonate, cocoglycerides or mixtures of C ₁₂ -C ₁₅ -alkyl benzoate and 2-ethylhexyl isostearate, mixtures of C ₁₂ -C ₁₅ -alkyl benzoate and butylene glycol dicaprylate / dicaprate and mixtures of C ₁₂ -C ₁₅ alkyl benzoate, 2-ethylhexyl isostearate and isotridecyl isononanoate. Of the hydrocarbons, paraffin oil, cycloparaffin, squalane, squalene, hydrogenated polyisobutene or polydecene advantageous to use in the context of the present invention.

auszeichnen, wobei R¹¹ und R¹² typischerweise unverzweigte aliphatische Reste mit 15 oder 17 Kohlenstoffatomen und bis zu 4 cis-Doppelbindungen darstellen.The oil can also be selected from the group of phospholipids. The phospholipids are phosphoric acid esters of acylated glycerols. Of the utmost importance among the phosphatidylcholines are, for example, the lecithins, which are distinguished by the general structure

in which R ¹¹ and R ^{12 are} typically straight-chain aliphatic radicals having 15 or 17 carbon atoms and up to 4 cis double bonds.

Can be used as according to the invention advantageous paraffin oil according to the invention Mercury Weissoel Pharma 40 from Merkur Vaseline, Shell Ondina ^® 917, Shell Ondina ^® 927, Shell Oil 4222, Shell Ondina ^® 933 from Shell & DEA Oil, Pioneer ^® 6301 S, Pioneer ^® 2071 (Hansen & Rosenthal ) are used. Suitable cosmetically acceptable oil and fat components are in Karl-Heinz Schrader, Basics and Formulations of cosmetics, 2nd edition, Verlag Hüthig, Heidelberg, p. 319-355 , which is incorporated herein by reference.

Ethiolated glycerol fatty acid esters

When ethiolated glycerol fatty acid esters can For example, PEG-10 olive oil glycerides, PEG-11 avocado oil glycerides, PEG-11 cocoa butter glycerides, PEG-13 sunflower oil glycerides, PEG-15 glyceryl isostearate, PEG-9 coconut fatty acid glycerides, PEG-54 hydrogenated castor oil, PEG-7 hydrogenated castor oil, PEG-60 hydrogenated castor oil, jojoba oil Ethoxylate (PEG-26 Jojoba Fat Acids, PEG-26 jojoba alcohol), glycereth-5 cocoate, PEG-9 coconut fatty acid glycerides, PEG-7 glyceryl cocoate, PEG-45 palm oil glycerides, PEG-35 castor oil, olive oil PEG-7 Esters, PEG-6 caprylic acid / capric acid glycerides, PEG-10 olive oil glycerides, PEG-13 sunflower oil glycerides, PEG-7 hydrogenated castor oil, Hydrogenated palm kernel oil glyceride PEG-6 esters, PEG-20 corn oil glycerides, PEG-18 Glyceryl Olead Cocoate, PEG-40 Hydrogenated Castor Oil, PEG-40 Castor Oil, PEG-60 Hydrogenated castor oil, PEG-60 corn oil glycerides, PEG-54 hydrogenated castor oil, PEG-45 palm kernel oil glycerides, PEG-35 castor oil, PEG-80 glyceryl cocoate, PEG-60 almond oil glycerides, PEG-60 "Evening Primrose" glycerides, PEG-200 Hydrogenated glyceryl palmitate and PEG-90 glyceryl isostearate included.

Ethoxylated oils

preferred ethoxylated oils are PEG-7 glyceryl cocoate, PEG-9 coconut glycerides, PEG-40 hydrogenated castor oil, PEG-200 hydrogenated glyceryl palmitate. Ethoxylated glycerol fatty acid esters are dissolved in aqueous Cleaning formulations used for various purposes. Low ethoxylated glycerol fatty acid esters (3-12 ethylene oxide units) usually serve as a moisturizer to improve the skin feel after drying, glycerol fatty acid ester with a degree of ethoxylation from about 30-50 serve as solubilizers for nonpolar Substances such as perfume oils. Highly ethoxylated glycerol fatty acid esters are used as thickeners. All these substances are common, that they are on the skin when used in dilution with Water a special skin feeling produce

surfactants

Suitable surfactants are all surface-active and wash-active substances. For example, there can be used: phosphoric esters and salts such as DEA-oleth-10 phosphate and dilaureth-4-phosphate, alkylsulfonates such as sodium cocosmonoglyceride sulfate, sodium C _12-14 olefinsulfonate, sodium laurylsulfoacetate and magnesium PEG-3 cocamide sulfate, carboxylic acids and derivatives such as lauric acid Aluminum stearate, magnesium alkoxide and zinc undecylate, ester carboxylic acids, for example calcium stearoyl lactylate, laureth-6 citrate and sodium PEG-4 lauramide carboxylate, esters formed by esterification of carboxylic acids with ethylene oxide, glycerol, sorbitan or other alcohols, Ethers, for example ethoxylated alcohols, ethoxylated lanolin, ethoxylated polysiloxanes, propoxylated POE ethers and alkyl polyglycosides such as lauryl glucoside, decyl glycoside and cocoglycoside.

Polysorbate

• – Polyoxyethylen(20)sorbitanmonolaurat (Tween 20, CAS-Nr. 9005-64-5)
• – Polyoxyethylen(4)sorbitanmonolaurat (Tween 21, CAS-Nr. 9005-64-5)
• – Polyoxyethylen(4)sorbitanmonostearat (Tween 61, CAS-Nr. 9005-67-8)
• – Polyoxyethylen(20)sorbitantristearat (Tween 65, CAS-Nr. 9005-71 -4)
• – Polyoxyethylen(20)sorbitanmonooleat (Tween 80, CAS-Nr. 9005-65-6)
• – Polyoxyethylen(5)sorbitanmonooleat (Tween 81, CAS-Nr. 9005-65-5)
• – Polyoxyethylen(20)sorbitantrioleat (Tween 85, CAS-Nr. 9005-70-3).

Suitable polysorbates are, for example:

• Polyoxyethylene (20) sorbitan monolaurate (Tween 20, CAS No. 9005-64-5)
• Polyoxyethylene (4) sorbitan monolaurate (Tween 21, CAS No. 9005-64-5)
• Polyoxyethylene (4) sorbitan monostearate (Tween 61, CAS No. 9005-67-8)
• Polyoxyethylene (20) sorbitan tristearate (Tween 65, CAS No. 9005-71 -4)
• Polyoxyethylene (20) sorbitan monooleate (Tween 80, CAS No. 9005-65-6)
• Polyoxyethylene (5) sorbitan monooleate (Tween 81, CAS No. 9005-65-5)
• Polyoxyethylene (20) sorbitan trioleate (Tween 85, CAS No. 9005-70-3).

• – Polyoxyethylen(20)sorbitanmonopalmitat (Tween 40, CAS-Nr. 9005-66-7)
• – Polyoxyethylen(20)sorbitanmonostearat (Tween 60, CAS-Nr. 9005-67-8).

Particularly advantageous are in particular

• Polyoxyethylene (20) sorbitan monopalmitate (Tween 40, CAS No. 9005-66-7)
• Polyoxyethylene (20) sorbitan monostearate (Tween 60, CAS No. 9005-67-8).

conditioners

As conditioning agents, it is possible, for example, to use all compounds which are described in the International Cosmetic Ingredient Dictionary and Handbook (Volume 4, publisher: RC Pepe, JA Wenninger, GN McEwen, The Cosmetic, Toiletry, and Fragrance Association, 9th Edition, 2002 ) are listed under Section 4 under the headings Hair Conditioning Agents, Humectants, Skin Conditioning Agents, Skin Conditioning Agents Emollient, Skin Conditioning Agents Humectant, Skin Conditioning Agents Miscellaneous, Skin Conditioning Agents Occlusive and Skin Protectants as well as all in the EP-A 934 956 (S.11-13) under "water soluble conditioning agent" and "oil soluble conditioning agent" Other substances which can be used advantageously as conditioning agents are, for example, the compounds designated as polyquaternium according to INCI (in particular Polyquaternium-1 to Polyquaternium-56) The substances which can be used include, for example, polymeric quaternary ammonium compounds, cationic cellulose derivatives and polysaccharides.

As conditioning agents, the compounds shown in the following table can also be used. Designation according to INCI CAS number polymer type Example (trade name) Polyquaternium-2 CAS 63451-27-4 Urea, N, N ', bis [3- (dimethylamino) propyl] -polymer with 1,1'-oxybis (2-chloroethane) Mirapol ^® A-15 Polyquaternium-5 CAS 26006-22-4 Acrylamide, methacryloxyethyltriethylammonium methosulfate Polyquaternium-6 CAS 26062-79-3 N, N-dimethyl-N-2-propenyl-2-propenaminiumchlorid Merquat ^® 100 Polyquaternium-7 CAS 26590-05-6 N, N-dimethyl-N-2-propenyl-2-propenaminium chloride, 2-propenamide Merquat ^® S Polyquaternium-10 CAS 53568-66-4 55353-19-0 54351-50-7 68610-92-4 81859-24-7 Quaternary ammonium salt of hydroxyethylcellulose Celquat ^® SC-230M, Polymer JR 400 Polyquaternium-11 CAS 53633-54-8 Vinylpyrrolidone / dimethylaminoethyl methacrylate copolymer / diethyl reaction product Gafquat ^® 755N Polyquaternium-16 CAS 29297-55-0 Vinylpyrrolidone / vinylimidazolinum methochloride copolymer Luviquat.RTM ^® HM552 Polyquaternium-17 CAS 90624-75-2 Mirapol ^® AD-1 Polyquaternium-19 CAS 110736-85-1 Quaternized water-soluble polyvinyl alcohol Polyquaternium-20 CAS 110736-86-2 Water-dispersible quaternized polyvinyl octadecyl ether Polyquaternium-21 Polysiloxanpolydimethyldimethylam-ammonium acetate copolymer Abil ^® B 9905 Polyquaternium-22 CAS 53694-17-0 Dimethyldiallylammonium chloride / acrylic acid copolymer Merquat ^® 280 Polyquaternium-24 CAS 107897-23-5 Polymeric quaternary ammonium salt of hydroxyethylcellulose Quartisoft ^® LM-200 Polyquaternium-28 CAS 131954-48-8 Vinylpyrrolidone / methacrylamidopropyltrimethylammonium chloride copolymer Gafquat ^® HS-100 Polyquaternium-29 CAS 92091-36-6, 148880-30-2 Chitosan, which reacted with propylene oxide u. was quaternized with epichlorohydrin ^® Lexquat CH Polyquaternium-31 CAS 136505-02-7, 139767-67-7 Polymeric, quaternary ammonium salt obtained by the reaction of DMAPA acrylates / acrylic acid / Acrylonitrogens copolymers u. Diethyl sulfate is produced Hypan ^® QT 100 Polyquaternium-32 CAS 35429-19-7 N, N, N-trimethyl-2- ([82-methyl-1-oxo-2-propenyl) oxy] -ethanaminium chloride, polymer with 2-propenamide Polyquaternium-37 CAS 26161-33-1 Polyquaternium-44 Copolymer quaternary ammonium salt of vinylpyrrolidone and quaternized imidazoline Table 3: Substances which can be used advantageously as conditioning agents

More advantageously be used as conditioning agent substances are for example cellulose derivatives and quaternized guar gum derivatives, in particular guar hydroxypropylammonium (z. B. Jaguar Excel ^®, Jaguar ^® C 162 (Rhodia), CAS 65497-29-2, CAS 39421-75-5).

And nonionic poly-N-vinylpyrrolidone / polyvinyl acetate copolymers (z. B. Luviskol ^® VA 64 (BASF Aktiengesellschaft)), anionic acrylate copolymers (eg. B. Luviflex ^® Soft (BASF Aktiengesellschaft)), and / or amphoteric amide / acrylate / methacrylate copolymers (e.g., B. Amphomer ^® (National Starch)) can be used advantageously in the present invention as conditioning agents.

powder raw materials

One Addition of powder raw materials can generally be advantageous. When Powder raw material can different substances are used. Particularly preferred the use of talc.

dyes

When Dyes come all liquid or in a solvent, z. B. in the application medium detachable Dyes or colored substances into consideration. For dermocosmetics, Pharmaceuticals, foods and feeds are preferred dyes used that for suitable for human and animal use, i. which usually no harmful or alergic effects, and are authorized. Examples for such Dyes are in the publication "Cosmetic Dyes" of the Dye Commission of the Germans Research Community, published compiled by Verlag Chemie, Weinheim, 1984. The connections (V) can be used as dyes. Unless the above connections (V) are used in addition to dyes, these dyes merely other dyes mean the above compounds (V) do not include.

pigments

Substances usable as pigments are practically insoluble colored substances in the application medium and may be inorganic or organic. Also inorganic-organic mixed pigments are possible. Preference is given to inorganic pigments. The advantage of inorganic pigments is their excellent light, weather and temperature resistance. The inorganic pigments may be of natural origin, for example made from chalk, ocher, umber, green earth, baked Terra di Siena or graphite. The pigments may be white pigments such as titanium dioxide or zinc oxide, black pigments such as iron oxide black, colored pigments such as ultramarine or iron oxide red, luster pigments, metal effect pigments, pearlescent pigments and fluorescent or phosphorescent pigments, wherein preferably at least one pigment colored, non-white pigment. Suitable are metal oxides, hydroxides and oxide hydrates, mixed phase pigments, sulfur-containing silicates, metal sulfides, complex metal cyanides, metal sulfates, chromates and molybdate and the metals themselves (bronze pigments). Titanium dioxide (CI 77891), black iron oxide (CI 77499), yellow iron oxide (CI 77492), red and brown iron oxide (CI 77491), manganese violet (CI 77742), ultramarines (sodium aluminum sulfosilicates, CI 77007, Pigment Blue 29 ), Chromium oxide hydrate (C177289), iron blue (Ferric Ferro-Cyanide, CI7751 0), Carmine (Cochineal). Particular preference is given to pearlescent and color pigments based on mica or mica which are coated with a metal oxide or a metal oxychloride such as titanium dioxide or bismuth oxychloride and optionally further coloring substances such as iron oxides, iron blue, ultramarines, carmines, etc., and the color is determined by varying the layer thickness can be. Such pigments are sold, for example under the trade names Rona ^®, Colorona ^®, Dichrona and Timiron ^{® ®} (Merck). Organic pigments include, for example, the natural pigments sepia, cambogia, bone charcoal, Kasseler brown, indigo, chlorophyll and other plant pigments. Synthetic organic pigments include azo pigments, anthraquinoids, indigoids, dioxazine, quinacridone, phthalocyanine, isoindolinone, perylene and perinone, metal complex, alkali blue and diketopyrrolopyrrole pigments.

pearlizing

Substances which can be used as pearlescing agents are those substances which can produce or impart a gloss effect. For example, these are alkylene glycol esters, special ethylene glycol disterate; Fatty acid alkanolamides, especially coconut fatty acid diethanoamide; Partial glycerides, especially stearic acid monoglyceride; Esters of polybasic, optionally hydroxy-substituted carboxylic acids with fatty alcohols having C ₆ -C ₂₂ carbon atoms, especially long-chain esters of tartaric acid; Fats, such as fatty alcohols, fatty ketones, fatty aldehydes, fatty ethers and fatty carbonates, which in total have at least 24 carbon atoms, especially laurone and distearyl ether; Fatty acids such as stearic acid, hydroxystearic acid or behenic acid, ring-opening products of olefin epoxides having C ₁₂ -C ₂₂ carbon atoms with fatty alcohols having C ₁₂ -C ₂₂ carbon atoms and / or polyols having C ₂ -C ₁₅ carbon atoms and C ₂ -C ₁₀ hydroxyl groups and mixtures thereof.

thickener

thickener are substances that increase the viscosity can act. For example, they can used for it be the viscosity to increase a mixture. As a thickener can for example, crosslinked polyacrylic acids and their derivatives, polysaccharides and their derivatives, such as xanthan gum, agar-agar, alginates or tyloses, Cellulose derivatives, e.g. Carboxymethylcellulose or hydroxycarboxymethylcellulose, Fatty alcohols, monoglycerides and fatty acids, polyvinyl alcohol and Polyvinylpyrrolidone can be used. Preference is given to nonionic Thickener used.

repellent

Repellent agents are compounds which are capable of preventing or repelling certain animals, especially insects, from humans or animals, such as farm animals and domestic animals. For this purpose, for example, can be used: 2-ethyl-1,3-hexanediol, N, N-diethyl-m-toluamide, etc. Suitable hyperemic effect de substances that stimulate the circulation of the skin are, for. B. essential oils, such as mountain pine extract, lavender extract, rosemary extract, juniper berry extract, horse chestnut extract, birch leaf extract, hay flower extract, ethyl acetate, camphor, menthol, peppermint oil, rosemary extract, eucalyptus oil, etc. Suitable keratolytic and keratoplastic substances such. As salicylic acid, calcium thioglycolate, thioglycolic acid and its salts, sulfur, etc. Suitable antidandruff agents are, for. Sulfur, sulfur polyethylene glycol sorbitan monooleate, sulfur ricinol polyethoxylate, zinc pyrithione, aluminum pyrithione, etc. Suitable antiphlogistic agents which counteract skin irritation include, for example, allantoin, bisabolol, drago santol, chamomile extract, panthenol, etc.

Pharmaceutically acceptable polymers

When pharmaceutically acceptable polymers are, for example, cationic Polymers with the name Polyquaternium according to INCI, z. B. copolymers vinylpyrrolidone / N-vinylimidazolium salts (Luviquat FC, Luviquat HM, Luviquat MS, Luviquat & commat, Care), copolymers of N-vinylpyrrolidone / dimethylaminoethyl methacrylate, quaternized with diethyl sulfate (Luviquat PQ 11), copolymers of N-vinylcaprolactam / N-vinylpyrrolidone / N-vinylimidazolium salts (Luviquat E Hold), cationic cellulose derivatives (Polyquaternium-4 and -10), Acrylamidocopolymere (Polyquaternium-7) and chitosan into consideration.

Suitable cationic (quaternized) polymers are also merquat (polymer based on dimethyldiallyl ammonium chloride), gafquat (quaternary polymers formed by reaction of polyvinylpyrrolidone with quaternary ammonium compounds), polymer JR (hydroxyethylcellulose with cationic groups) and cationic polymers based on plants, e.g. As guar polymers, such as the Jaguar ^® brands from Rhodia.

Further substances which can be used as polymers are neutral polymers, such as polyvinylpyrrolidones, copolymers of N-vinylpyrrolidone and vinyl acetate and / or vinyl propionate, polysiloxanes, polyvinylcaprolactam and other copolymers with N-vinylpyrrolidone, polyethyleneimines and their salts, polyvinylamines and their salts, cellulose derivatives, polyaspartic acid salts and derivatives , This includes, for example Luviflex® ^® 0 Swing (partially hydrolyzed copolymer of polyvinyl acetate and polyethylene glycol, BASF Aktiengesellschaft).

Suitable polymers are also nonionic, water-soluble or water-dispersible polymers or oligomers, such as polyvinyl caprolactam, z. B. Luviskol ^® 0 Plus (BASF), or polyvinylpyrrolidone and copolymers thereof, in particular with vinyl esters, such as vinyl acetate, for. B. Luviskol ^® 0 VA 37 (BASF), polyamides, z. B. based on itaconic acid and aliphatic diamines, as z. B. in the DE-A-43 33 238 are described.

Suitable polymers are also amphoteric or zwitterionic polymers, such as those available under the names Amphomer ^® (National Starch) octylacrylamide / methyl methacrylate / tert-butylaminoethyl methacrylate-hydroxypropyl methacrylate copolymers and zwitterionic polymers, as described for example in the German patent applications DE 39 29 973 . DE 21 50 557 . DE 28 17 369 and DE 37 08 451 are disclosed. Acrylamidopropyltrimethylammonium chloride / acrylic acid or methacrylic acid copolymers and their alkali metal and ammonium salts are preferred zwitterionic polymers. Further suitable zwitterionic polymers are methacroylethylbetaine / methacrylate copolymers (AMERCHOL) are commercially available under the name Amersette® ^®, and copolymers of hydroxyethyl methacrylate, methyl methacrylate, N, N-dimethylaminoethyl methacrylate and acrylic acid (Jordapon (D)).

Suitable polymers are also nonionic, siloxane-containing, water-soluble or -dispersible polymers, for. As polyether siloxanes, such as Tegopren ^® 0 (Goldschmidt) or Besi & commat (Wacker).

Solids or liquids or mixtures thereof:

Of the Expression solids or liquids or mixtures thereof is to be understood very broadly. Among them are with the exception of antioxidants, mixtures (M1) and (M2), preparations, dye, Vesicles, carotenoid formulations, dermocosmetics, pharmaceuticals, Food and feed, in principle all solids or liquids or mixtures thereof that are naturally occurring or artificially produced are. Not included are the natural ones Sources of compounds (V). This includes preferred all tradable products. Products are both basic and precursor products, which can serve for the production of sales products and the sales products themselves. According to one of the preferred embodiments These are adhesives. After another preferred Embodiment are Under this paint, colors and other dyes to understand. In a another embodiment are solids or liquids or mixtures thereof solvents, Monomers, oligomers and polymers. Other embodiments may include fuels and mineral oils be. embodiments can also be construction chemicals and building materials. Embodiments are also chemicals for the Agriculture, for example crop protection or fertilizers. In a further embodiment they are dispersions and in another exemplary embodiment colored Papers.

Preparation of compounds (V)

The compounds (V) belong to the class of aromatic carotenoids, which are widespread in nature and occur in great variability. Carotenoids are produced by many photosynthetically active and some photosynthetically inactivated organisms. The biochemical pathway up to the basic carotenoid structure has been well studied and is the same for the majority of organisms ( Armstrong, G., 1999, in DHR Barton & K. Nakanishi, Comprehensive Natural Products Chemistry, Vol. 2, 321-352 ).

Under natural circumstances, 3,3'-dihydroxyisorenieratin is present in microorganisms such as Streptomyces mediolani or Brevibacterium linens. In Brevibacterium linens it occurs together with its biochemical precursors (Isorenieraten and 3-hydroxy-isorenieraten) and is responsible for the gelbrötliche coloring of the bacterium ( Kohl et al., 1983, Phytochemistry 22, 207-210 ). Brevibacterium linens in turn is a component of the complex compound bacterial lubrication on red smear cheese z. As Limburger, Münster, Brick, Tilsiter and Appenzeller and can be isolated from there. To facilitate finding colonies containing 3,3'-dihydroxyisorenieratin, one can take advantage of reacting with alkali. The resulting ionization of the phenolic ring results in a bathochromic effect, which leads to a color change from yellow-orange to pink-violet ( Rattray, FP, Fox, PF 1999, Journal of Dairy Science, 82, 891-909 ).

3,3'-Dihydroxyisorenieratin can be prepared in a variety of ways. So far, the isolation from microorganisms has been preferred. DE 18 08 514 discloses a process for the preparation of 3,3'-dihydroxyisorenieratin. In the method, a 3,3'-Dihydroxyisorenieraten producing organism (Streptomyces mediolani) is grown in culture and added to feed as dried and ground cell powder. Alternatively, an extract of this organism containing 3,3'-dioxyisorenieratin can be used.

In WO 2005/007826 A2 describes a method by which cyclic carotenoids are converted by bioconversion into aryl carotenoids. For this purpose, a codon-optimized gene of a carotene desaturase is expressed in a Gram negative host cell. Isorenierates can be prepared by this method which can act as a precursor to the production of 3,3'-dihydroxyisorenieratin.

In a scientific publication, a gene for a cytochrome P450 monooxygenase from Brevibacterium aurantiacum has been described, whose gene product is highly likely to bioconvert isorenates to 3,3'-dihydroxyisorenieratin ( Dufosse, L et al., Brevibacterium linens ATCC 9175 (Brevibacterium aurantiacum sp., Nov.) involves a cytochrome P450 monooxygenase, Food Research International, 2005, 38, 967-973 ).

Alternatively, 3,3'-dihydroxyisorenieratin can be synthesized. Possible synthetic routes are in the writings EP 06116819.1 and EP 06116816.7 described.

By oxidation, 3,3'-dihydroxyisorenieratin can be converted to the blue 3,3'-dihydroxyisorenieratin-1-quinone (II). It is thus understood that the intermediate of these reactions, 3-hydroxyisorenieratin-3'-quinone, can occur in both 3,3'-dihydroxyisorenieratin and 3,3'-dihydroxyisorenieratin-1-quinone or mixtures thereof. The preparation of 3,3'-dihydroxy-2,2 ', 4,4'-tetra-tert-butylisorenieratin-1-quinone (III) and 3,3'-dihydroxy-2,2', 4,4'- tetra-tert-butylisorenieratin (IV) is in the Dissertation by Markus Schmidt (University of Düsseldorf, 2001, page 35 ff) described.

The in the antioxidants according to the invention, Mixtures (M1 or (M2), preparations, colorants, vesicles, carotenoid formulations, Dermocosmetics, pharmaceuticals, food and feed or the solids or liquids or mixtures contained or used for their preparation Compounds (V) or mixtures thereof, in particular the one used 3,3'-Dihydroxyisorenieratin can by the natural one or influenced metabolism of an organism or be synthesized in whole or in part. metabolism of organisms for example by special fermentation techniques such as biocatalysis or genetically manipulated.

The compounds (V) are advantageously used in enriched form and / or in pure form. This is especially true for compound (I), most especially for 3,3'-dihydroxyisomerate. An enriched form is to be understood as meaning a concentration of the particular compound considered which is higher than the concentration in which the particular compound in its natural source, for example in Streptomyces me diolani or Brevibacterium linens. If several natural sources of compounds (V) are available, the concentration will refer to the natural source or sources from which it has been enriched. In the enriched form, this concentration is preferably 2x, 3x, 4x, 5x, 6x, 7x, 8x, 9x, 10x, 20x, 30x, 40x, 50x, 60x, 70x, 80x, 90x, 100x or more than 100x higher. In pure form, the compounds (V) having a purity in the range of 1 to 100% wt .-%, preferably 10 to 100%, more preferably in a range of 30 to 100%, most preferably from 50 to 100% and most preferably from 75 to 100%, based on the total weight of the above-mentioned compounds. Particular preference is given to crystals of the respective compounds (V) having a purity of greater than 75% by weight, preferably greater than 90% by weight, particularly preferably greater than 95% by weight, very particularly preferably greater than 98% by weight, based on the total weight of the respective crystals used.

The Compounds (V) or mixtures thereof derived from natural Source, can in mixture with other carotenoids and phospholipids occur. The content of other carotenoids with the exception of the compounds (V) and phospholipids for each of the compounds (V) is preferably below one weight percent of 95%, 90%, 80%, 70%, 60%, 50%, 40% 30%, 20%, 10%, 5%, 1%, 0.5% or 0.05% based on the total weight of the particular compound.

Especially They are advantageous with a low phospholipid content, the approximately over the Phosphorus content can be determined. The phosphorus content should, especially for the compounds (V) used in carotenoid formulations become smaller as 2 wt .-%, advantageously less than 1.0 wt .-%, preferably less than 0.5 wt .-%, especially preferably less than 0.1% by weight, very particularly preferably less than 0.02 Wt .-%, based on the total amount of the carotenoid formulation be.

antioxidants

object of the present invention are antioxidants containing at least an isoreniertatin compound (I). Furthermore, the antioxidants of the invention contain one or more of the isorenieratin compounds (I). According to one of the preferred embodiments contain the antioxidants of the invention only one Irorenieratin compound (I). Particularly preferred 3,3'-dihydroxyisorenieratin as Antioxidant according to the invention used. According to another preferred embodiment, the antioxidant of the invention in addition to one or more Isorenieratin compounds (I) additionally other substances contain. For example, other antioxidants are advantageous, Peroxide decomposers, radical decomposers or other carotenoids. For example can in addition to the isorenieratin compounds (I), one or more of the compounds (II) to (IV) contained in the antioxidants of the invention be. Of these, the antioxidants according to the invention are preferred For example, a mixture (M1) containing at least one isorenieratin compound (I) and 3,3'-Dihydroxyisorenieratene-1-quinone (II) or 3,3'-dihydroxy-2,2 ', 4,4'-tetra-tert-butylisorenieratin-1-quinone (III) or mixtures of these, or mixture (M2), containing, 3'-dihydroxy-2,2 ', 4,4'-tetra-tert-butylisorenieratin (IV) and at least one isorenieratin compound (I) or a mixture (M1).

The Antioxidants of the invention can from an antioxidant ingredient or from several antioxidant ingredients consist. These antioxidant components are the compounds (V) mentioned above, preferably 3,3'-dihydroxyisorenieratin, their mixtures and other substances, such as other antioxidants, Peroxide decomposers, radical decomposers, organic and inorganic Solvents, oils, fats or waxes. For The preparation of the antioxidants according to the invention can be Antioxidant ingredients in enriched, pure or crystalline Form to be used. The antioxidant components can hereby in solid form or in a suitable solvent. suitable solvent are, for example, organic or inorganic solvents or fats, oils and waxes. Organic or inorganic are preferred here Solvent, Fats, oils and waxes dermocosmetic, pharmaceutical, for the human or for the animal consumption or for several of these purposes are permitted. The antioxidant ingredients can be mixed in one step or in several steps. Has been at least one liquid Antioxidantsbestandteil used, then the antioxidant can be dried or so left.

The Amount of the respective compound selected from the compounds (V), to the other antioxidant ingredients, depending on the number of Antioxidant ingredients and the intended use and desired Properties of the antioxidant, can be varied. It can, for example in the range of 0.01%, 0.05%, 1%, 5%, 10%, 20%, 30%, 40%, 50%, 60%, 70%, 80%, 90%, 95% or 100 wt .-% based on the respective total weight are. The proportions of the other antioxidant components is also very variable and can be used for any additional antioxidant component vary in the same areas.

The Antioxidants of the invention can in a process for the preparation of mixtures, passages, colorants, Vesicles, carotenoid formulations, dermocosmetics, pharmaceuticals, Food or feed, gelatin capsules or other solids or liquids or mixtures thereof.

Mixtures (M1) and M2)

One Another object of the invention are mixtures (M1) containing at least one isorenieratin compound (I) and 3,3'-dihydroxyisorenieratin-1-quinone (II) or 3,3'-dihydroxy-2,2 ', 4,4'-tetra-tert-butylisorenieratin-1-quinone (III) or mixtures of these or mixtures (M2) containing 3,3'-dihydroxy-2,2 ', 4,4'-tetra-tert-butylisorenieratin (IV) and at least one isorenieratin compound (I) or a mixture (M 1). The mixtures (M1) or (M2) preferably contain 3,3'-dihydroxyisorenieratin.

The mixtures according to the invention (M1) or (M2) from a mixture component or from several mixture components consist. These compounding ingredients are compounds (V), preferred 3,3'-Dihydroxyisorenieratene, their mixtures and other substances, for example other antioxidants, peroxide decomposers, Radical decomposers, organic and inorganic solvents, oils, fats or waxes. Other substances are, for example, for the preparation of the mixtures (M1) or (M2) the mixture ingredients can be used in enriched, pure or crystalline form. The blend ingredients can in this case in solid form or in a suitable solvent available. Suitable solvents are for example, organic or inorganic solvents or fats, oils and waxes. Preference is given here to organic or inorganic solvents, Fats, oils and waxes dermocosmetic, pharmaceutical, for the human or for the animal consumption or for several of these purposes are permitted. The blend ingredients can be mixed in one step or in several steps. Has been at least one liquid Mixing component used, so the mixtures (M1) or (M2) subsequently be dried or left as is.

The Amount of the respective compound selected from the compounds (V), to the other mixture constituents, depending on the number of mixture components and the intended use and desired Properties of the mixtures (M1) or (M2) can be varied. It For example, in the range of 0.01%, 0.05%, 1%, 5%, 10 %, 20%, 30%, 40%, 50%, 60%, 70%, 80%, 90%, 95% or 100 Wt .-% based on the total weight. The proportions The other components of the mixture are also very variable and can for each further mix ingredient will vary in the same areas.

The Compounds (V) or the mixtures (M1) or (M2) are suitable for the preparation of mixtures in which material properties are positive should be combined or influenced. For example, next to a high antioxidant effect even on a particular color impression Value, so can for example, the 3,3'-dihydroxyisorenieratin also as a mixture with the blue 3,3'-dihydroxyisorrenieratin-1-quinone (II) or with the red BHT carotenoid (IV) or 3,3'-dihydroxy-2,2 ', 4,4'-tetra-tert-butylisorenieratin-1-quinone (III) or other isorenieratin compounds (I) or other carotenoids or with mixtures of these. Due to the different coloring and the high antioxidant effect it is possible different mixtures (M1) or (M2) with different colors and antioxidant effect. The mixtures (M1) or (M2) can for many Purposes are used and must in their composition for be adapted to the respective purpose. By the composition of the mixtures (M1) or (M2) not only the antioxidant effect or the coloring, but also for example positively influenced the health properties, or the Properties of vesicles, for example their stability or staining, varies become.

The Mixtures (M1) or (M2) are suitable for the production of passages, colorants, Vesicles, carotenoid formulations, dermocosmetics, pharmaceuticals, Food or feed, gelatine capsules or other solids or liquids or mixtures thereof

preparations

In a further embodiment are the antioxidants of the invention, Mixtures, colorants, Vesicles or carotenoid formulations dermocosmetics, food or feed, solids or liquids or mixtures added by these. For this purpose can they are present in preparations. As examples of such preparations may be mentioned are: amino acid or vitamin concentrates but also flavors.

The Riots can Preparations of antioxidants, mixtures (M1) or (M2), colorants, Vesicles or carotenoid formulations may and may be considered ready-mixed or as a composition of preparation ingredients, which are mixed before their application occur. These compilations can the preparation ingredients each separately or one or more Preparation ingredients separated from a mixture of other ingredients of the preparation include. The preparation ingredients can be used individually or in mixtures of one or more constituents of preparation and possibly further Substances such as solvents, at the same time or different times the dermocosmetics, Pharmaceuticals, food or feed, solids or liquids or mixtures thereof are added.

When In this case, the preparation component is any compound or substance understood, which is included in the preparation. Examples of such Preparatory constituents are, for example, the compounds (V), other carotenoids, other antioxidants, minerals, enzymes, Vitamins, organic acids, Trace elements, vitamins, enzymes, amino acids, minerals, or adjuvants such as emulsifiers, stabilizers, preservatives, anti-caking agents, solvent and / or flavor enhancers.

The Preparation ingredients can in the form of liquids, dispersions, suspensions, for example or as a solid and in the same or different enriched, pure or crystalline form.

The Choice of the preparation components depends on the selected field of application the preparations. For dermocosmetic or pharmaceutical preparations may include Preparing ingredients of all for dermocosmetic or pharmaceutical Preparations of suitable substances. For food or feed intended preparations can all for the human or animal nutrition harmless and / or approved substances or mixtures of substances. These can be natural or of synthetic origin.

Examples for in Coming representatives of the substance classes mentioned can the applicable lists for Food additives taken from European legislation be, for. B. the current EC Directive 95/2 / EC.

These Preparation ingredients are the preparations, according to their different properties and depending on the chosen field of application, attached in different quantities. The dependent of the chosen Field of application meaningful combinations of substance classes as well the quantitative mixing ratios are known to the skilled person. The examples of preparation ingredients listed here are particularly suitable for Preparations for Food and feed, can but also in dermocosmetics, especially in mouth, Dental or dental care or used in pharmaceuticals, provided for these uses are permitted.

In an embodiment the preparations become independent from the food or Feed as a liquid, Powder, tablet, capsule or suspension human or animal Organism in addition or separately from the normal food or feed become.

When For example, vitamins can be considered as preparation ingredients.

preferred Vitamins are: Vitamin A (Retinol), Vitamin D (Calciferole), Vitamin E (tocopherols and tocotrienols), vitamin K (phylloquinones and menaquinones), wherein vitamins A and E are preferred.

Especially for preparations for food and feed can also contain enzymes. Examples include: amylases, proteases and invertases.

When Preparing ingredient are eligible amino acids z. Glutamic acid, L-carnitine, L-glutamine, L-taurine, L-aspartic acid, L-glycine, L-lysine, DL-phenylalanine, L-tryptophan, Tyrosine, L-arginine, L-cysteine, L-leucine, DL-methionine, L-alanine, L-serine, L-threonine, L-citrulline, L-valine, L-histidine, L-isoleucine, L-ornithine or L-proline.

Especially Preferably, the essential amino acids such. L-isoleucine, L-leucine, L-lysine, DL-methionine, DL-phenylalanine, L-threonine, L-tryptophan and L-valine, especially The amino acids important in animal nutrition are preferably L-lysine, DL-methionine or L-threonine.

preferred Minerals for Food and feed are z. As sodium, potassium, magnesium, Calcium, phosphorus, iron and zinc.

suitable Trace elements are: chromium, iron, fluorine, iodine, cobalt, copper, manganese, Molybdenum, Nickel, selenium, vanadium, zinc or tin.

Prefers used organic acids for food and feed are z. Formic acid, propionic acid, lactic acid, acetic acid and Citric acid, Particularly preferred are formic acid, propionic acid or Lactic acid.

Further possible Preparatory ingredients, especially for food and feed are flavor enhancers. Under flavor enhancer in the sense of this invention are naturally occurring or artificial understood substances that the taste of life and To round off or strengthen feed.

When flavor enhancer can For example, flavors are also used, which are the compounds (V) not included. Examples include: E 620 glutamic acid, E 621 Monosodium glutamate, E 622 monopotassium glutamate, E 623 calcium diglutamate, E 624 monoammonium glutamate, E 625 magnesium diglutamate, E 626 guanylic acid, E 627 Disodium guanylate, E 628 dipotassium guanylate, E 629 calcium guanylate, E 630 inosinic acid, E 631 disodium inositol, E 632 dipotassium ininate, E 633 dicalcium inosinate, E 634 calcium 5-ribonucleotide, E 635 disodium 5-ribonucleotide, E 640 glycine and E 650 zinc acetate.

at the following E-numbers are the ones used in Directive 95/2 / EEC Designation for Food additives.

When other antioxidants can z. As ascorbic acid (vitamin C, E 300), sodium L-ascorbate (E 301), calcium L-ascorbate (E 302), ascorbyl palmitate (E 304), butylhydroxyanisole (E 320), butylhydroxytoluene (E 321), calcium disodium EDTA (E 385), Gallates such as For example, propyl gallate (E 310), octyl gallate (E 311), dodecyl gallate (Lauryl gallate) (E 312), isoascorbic acid (E 315), sodium isoascorbate (E 316), lecithin (E 322), lactic acid (E 270), multiple phosphates z. As diphosphates (E 450), triphosphates (E 451), polyphosphates (E 452), sulfur dioxide (E 220), sodium sulfite (E 221), sodium bisulfite (E 222), sodium disulfite (E 223), potassium sulfite (E 224), calcium sulfite (E 226), calcium hydrogen sulfite (E 227), potassium bisulfite (E 228), Selenium, tocopherols (vitamin E, E 306) such. Alpha-tocopherol (E 307), gamma-tocopherol (E 308), delta-tocopherol (E 309) and all tocotrienols, stannous chloride (E 512), citric acid (E 330), Sodium citrate (E 331), carotenoids, vitamin A and potassium citrate (E 332). Vitamins are both fat-soluble and water-soluble vitamins into consideration. At the fat-soluble Vitamins include: Vitamin B1 (thiamine), Vitamin B2 (Riboflavin), vitamin B5 (pantothenic acid), vitamin B6 (pyridoxine), Vitamin B12 (cobalamin), vitamin C (ascorbic acid), vitamin H (biotin), folic acid and Niacin, wherein the vitamins B2 and C are preferred.

For example, emulsifiers suitable for food and feed may be the following: E 420 sorbitol, E 420ii sorbitol syrup, E 421 mannitol, E 422 glycerol, E 431 polyoxyethylene (40) stearate, E 432 polyoxyethylene sorbitan monolaurate / polysorbate 20, E 433 polyoxyethylene sorbitan monooleate / polysorbate 80, E 434 polyoxyethylene sorbitan monopalmitate / polysorbate 40, E 435 polyoxyethylene sorbitan monostearate / polysorbate 60, E 436 polyoxyethylene sorbitan tristearate / polysorbate 65, E 440 pectins, E 440i pectin , E 440ii amidated pectin, E 442 ammonium phosphatides, E 444 sucrose acetate isobutyrate, E 445 glycerol ester from wood rosin, E 450 diphosphates, E 450i disodium diphosphate, E 450ii trisodium diphosphate, E 450iii tetrasodium diphosphate, E 450iv dipotassium diphosphate, E 450v tetrapotassium diphosphate, E 450vi Dicalcium diphosphate, E 450vii calcium dihydrogen diphosphate, E 451 triphosphates, E 451i pentasodium triphosphate, E 45111 pentapotassium triphosphate, E 452 polyphosphates, E 452i Nat ammonium polyphosphate, E 452ii potassium polyphosphate, E 452iii sodium calcium polyphosphate, E 452iv calcium polyphosphate, E 460 cellulose, E 460i microcrystalline cellulose, E 460ii cellulose powder, E 461 methylcellulose, E 463 hydroxypropylcellulose, E 464 hydroxypropylmethylcellulose, E 465 methylethylcellulose, E 466 carboxymethylcellulose, E 469 enzymatic hydrolysed carboxymethylcellulose, E 470a sodium, potassium and calcium salts of fatty acids, E 470b magnesium salts of fatty acids, E 471 mono- and diglycerides of fatty acids, E 472a acetic acid esters of mono- and diglycerides of fatty acids, E 472b lactic acid esters of mono- and diglycerides of Fatty acids, E 472c citric acid esters of mono- and diglycerides of fatty acids, E 472d tartaric acid esters of mono- and diglycerides of fatty acids, E 472e mono and diacetyl tartaric acid esters of mono- and diglycerides of fatty acids, E 472f mixed acetic and tartaric acid esters of mono- and diglycerides of fatty acids, E 473 sugar esters of fatty acids, E 474 sugar glycerides, E 475 polyglycerol esters of fatty acids, E 476 polyglycerol polyricinoleate, E 477 propylene glycol esters of fatty acids, E 479 Thermooxidised soybean oil with mono- and Diglycerides of fatty acids, E 481 sodium stearoyl-2-lactylate, E 482 calcium stearoyl-2-lactylate, E 483 stearyl tartrate, E 491 sorbitan monostearate, E 492 sorbitan tristearate, E 493 sorbitan monolaurate, E 494 sorbitan monooleate or E 495 sorbitan monopalmitate.

Under Stabilizers are in the context of the invention, in particular substances understanding the consistency or composition of food and feed. Examples include: ascorbic acid (E 300), Carbamit (E 927b), ferrous lactate (E 585), iron gluconate (E 579), glycerol ester (E 445), lecithin (E 322), meta-tartaric acid (E 353), Pectin (E 440), sucrose acetate isobutyrate (E 444) and stannous chloride (E 512)

preservative are substances which are the durability especially of dermocosmetics, Extend pharmaceuticals, foods and feeds by placing them before the harmful Protect effects of microorganisms. Examples include: E 200 sorbic acid, E 201 sodium sorbate, E 202 potassium sorbate, E 203 calcium sorbate, E 210 benzoic acid, E 211 sodium benzoate, E 212 potassium benzoate, E 213 calcium benzoate, E 214 ethyl p-hydroxybenzoate / PHB ester, E 215 sodium ethyl p-hydroxybenzoate / PHB ethyl ester Sodium salt, E 216 propyl p-hydroxybenzoate / PHB propyl ester, E 217 sodium propyl p-hydroxybenzoate / PHB propyl ester Sodium salt, E 218 methyl p-hydroxybenzoate / PHB methyl ester, E 219 Sodium methyl p-hydroxybenzoate / PHB Methylester Sodium salt, E 220 sulfur dioxide, E 221 sodium sulfite, E 222 sodium hydrogen sulfite / sodium bisulfite, E 223 sodium metabisulphite / sodium disulphite, E 224 potassium metabisulphite / potassium sulphite, E 226 calcium sulfite, E 227 calcium hydrogen sulfite, E 228 potassium hydrogen sulfite / potassium bisulfite, E 230 biphenyl / diphenyl, E 231 orthophenylphenol, E 232 sodium orthophenylphenol, E 233 thiaben dazole, E 234 nisin, E 235 natamycin, E 239 hexamethylenetetramine, E 242 dimethyl dicarbonate, E 249 potassium nitrite, E 250 sodium nitrite, E 251 sodium nitrate and E 252 potassium nitrate.

at Anticaking agents in the context of the present invention are of course occurring or artificial produced substances that reduce the flowability of a food or Increase feed, by preventing the particles from agglomerating and sticking together. Examples include: E 530 magnesium oxide, E 535 sodium ferrocyanide, E 536 potassium ferrocyanide, E 541 acid sodium aluminum phosphate, E 551 silica, E 552 calcium silicate, E 553ai magnesium silicate, E 553aii magnesium trisilicate (asbestos free), E 553b talc (asbestos free), E 554 sodium aluminum silicate and E 556 calcium aluminum silicate

In an embodiment can be used according to the invention Preparation of one or more additives as a preparation contain. Aggregates are substances according to the invention, the improvement of product properties, such as dust behavior, Flow properties, Water absorption capacity and storage stability serve. Aggregates can based on sugars z. As lactose or maltodextrin, on the Base of cereal or legume products z. Corn cob meal, wheat bran and soybean meal, on the base of mineral salts and the like Calcium, magnesium, sodium, potassium salts, as well also D-pantothenic acid or their salts themselves (chemically or fermentatively produced D-pantothenic acid salt) be.

In a further embodiment may be used according to the invention Preparations one or more so-called. Carrier as a preparation ingredient contain. As a carrier "inert" support materials, i. Materials that have no negative interactions with those in the inventive preparation show used components. Of course, the carrier material for the respective uses as adjuvant, eg. In food and animal feed, be safe. As support materials are suitable both inorganic as well as organic carriers. As examples of suitable support materials are: low molecular weight inorganic or organic compounds as well as higher molecular weight organic compounds natural or of synthetic origin. Examples of suitable low molecular weight inorganic carriers are salts such as sodium chloride, calcium carbonate, sodium sulfate and Magnesium sulfate kieselguhr or silica or silicic acid derivatives, z. As silicas, silicates or silica gels. Examples of suitable organic carrier in particular, sugars, e.g. As glucose, fructose, sucrose and Dextrins and starch products. As examples of high molecular weight organic carriers should be mentioned: starch and cellulose preparations, especially corn starch, Corncorn flour, ground rice hulls, Weizengrieskleie or cereal flours, such as. Wheat, rye, Barley and oatmeal or bran and mixtures thereof.

Of the Weight fraction of the antioxidants according to the invention, Mixtures (M1) or (M2), colorants, vesicles or carotenoid formulations in the preparations according to the invention can vary widely and is generally addressed for practical considerations resulting from the chosen Scope (eg livestock, pet ownership or human nutrition).

In an embodiment of the present invention those for use according to the invention suitable formulations Z. B. from 1 to 10 wt .-%, preferably from 10 to 20 wt .-%, particularly preferably from 20 to 30 wt .-%, completely more preferably from 30 to 40% by weight of antioxidant, mixtures (M1) or (M2), colorants, Vesicle or carotenoid formulation included. But it can also higher percentile shares chosen become.

The Preparation of the preparations according to the invention takes place in the simplest case by mixing the individual components. Similarly, the preparation by mixing solutions or dispersions of Preparatory ingredients are made and optionally subsequent removal of solvents or dispersants. The mixtures of different ingredients can present to each other in any weight ratios.

The The simplest form of the mixture is the bringing together of the preparation components in a mixer. Such mixers are known to the person skilled in the art, for example from the company Ruberg (vertical twin-shaft mixer (type HM (10-50,000 I)), ring-layer mixed granulator (type RMG), continuous agglomerator dryer (type HMTK), vertical single-shaft mixer (type VM (10-50,000 l)), container mixer (Type COM (50-4000 I)). Are possibly essential, because possibly preferred mixers in animal feed ?. Other mixers can z. B. also by the companies Lödige, Drais, Engelsmann be related. The mixers can be discontinuous or be operated continuously. In the batch mixer are generally all the ingredients to be mixed in the desired relationship submitted and then a sufficient time in the range of minutes mixed until hours. The mixing time and the mixing stress become determined so that the Zuberitunsbestandteile distributed homogeneously i.e. the individual preparation components evenly in the Preparation are distributed. In the case of continuous mixing the preparation ingredients are added continuously, optionally after a premix. Also in the continuous mixer is the Residence time and mixing stress to be selected so that the preparation ingredients homogeneously distributed in the mixture. The mixing time is in continuous case frequently shorter and the strain higher as in the case of the discontinuous mixture. The mixture is usually carried out at room temperature, but also in dependence the substances used at higher or lower temperatures.

The Preparations can in liquid, for example as a solution, Dispersion or as a suspension, or as a solid. In a preferred embodiment the preparations are present as a solid. Depending on the application technology Requirement can the preparations as a powder with an average particle size in one Range of 10 microns up to 5000 μm, preferably present with an average particle size in a range of 20 microns to 1000 microns. Mean particle size means Hereby, that at least 75% of the particles have a particle size within of the specified range.

The Particle distribution of the powdered products obtained in one Device of Malvern Instruments GmbH, Mastersizer S, to be investigated.

Mixtures of components are possible as pure blends, that is, the substances are mixed together in the desired particle sizes and concentration ratios, if necessary. With the addition of further preparation ingredients, wherein substances by z. B. a coating can be protected as necessary. Furthermore, core-shell structures can be used, ie one or more constituents of preparation are present as core inside and one or more further constituents of preparation as shell outside - or vice versa. Of course, further enclosures are also used in these structures, if necessary. It is also conceivable to encapsulate substances together in a common matrix of carrier materials or protective colloids. Examples of these are known in the art and z. In RA Morten: Fat-Soluable Vitamins, Pergamon Press, 1970, pages 131-145 , described.

The Preparation of the powders can be carried out by crystallization, precipitation, Drying, granulation or agglomeration process or other in the common textbooks described methods for forming solids.

dye

Another object of the invention are colorants containing the compounds (V). The colorants of the invention may consist of only the compounds (V), for example 3,3'-Dihydroxyisorenieraten or Dihydroxyisorenieratin-1-quinone exist. Likewise, it is possible that they contain or consist of different compounds (V). Furthermore, they can the antioxidants of the invention, Mixtures (M1) or (M2), preparations, vesicles or carotenoid formulations have been or have been prepared using them.

In addition, they can other substances (colorant components), as is the expert usually in colorants used included. Färbemittelbestandteile can For example, dispersing or suspending agents, emulsifiers or fats, oils and be waxes. Preferably, they contain other dyes and / or Pigments, for example other carotenoids.

to Preparation of the colorants the compound (V) are preferably in enriched form, especially preferably in pure form and most preferably in crystalline Form used.

to further increase stability the colorant can other antioxidants, Peroxidzersetzer, radical scavenger or Emulsifiers and oils, which is preferred for the application in or on the human or animal body allowed or dermocosmetically and pharmaceutically acceptable, as a colorant component be used.

The dye can be used alone or in the presence of Schutzkoloiden or these contain. Protective glycols are, for example, gelatin, fish gelatin, Strength, Dextrin, vegetable proteins, pectin, gum arabic, casein, caseinate or mixtures thereof. Further protective glycols are polyvinyl alcohol, polyvinylpyrrolidone, Methylcellulose, carboxymethylcellulose, hydroxypropylcellulose and alginates. The stability The aggregates can be positively influenced by the addition of plasticizers become. Therefor suitable plasticizers are for example sugar or Sugar alcohols such as sucrose, glucose, lactose, invert sugar, sorbitol, Mannitol or glycerine.

The Amounts of protective colloid, plasticizer and the compound or compounds (V) or other colorant ingredients in particular, other carotenoids in the colorants are generally chosen so that a final product of between 0.1 and 100 ppm is preferred between 0.5 and 50 ppm, more preferably 1 to 20 ppm of the above 20 to 200 ppm of a protective colloid, 20 to 200 ppm of a plasticizer and optionally small amounts of a Stabilizer included. The quantities refer to each on the total mass of the dyed Preparations, dermocosmetics, pharmaceuticals, food and feed or the solids, liquids or mixtures thereof.

The dye can be prepared by simple mixing. The colorant ingredients can be added sequentially or simultaneously and mixed. The Amounts of the compounds (V) possibly in the form of antioxidants, Mixtures (M1) or (M2), preparations, vesicles or carotenoid formulations is of the one you want Color effect and the intended use of the inventive colorants dependent. According to this, the type and amount of the other colorant constituents also depends. So be for colorants according to the invention, the for for human or animal use, for example as a use in dermocosmetics, pharmaceuticals, food and feed are preferred colorant ingredients used that for these uses are suitable and preferred.

The Compounds (V) can depending on the solvent and temperature in different form. In a preferred embodiment are the compounds (V) in the colorants in the form of aggregates, preferably H or J aggregates. These aggregates show in comparison with the monomeric forms a higher light stability on and are therefore for Particularly suitable applications in which reaches the highest possible light stability of the dyeing shall be. The aggregates can be generated, for example, that one solution of a or more of the compounds (V) optionally in admixture with others Substances, preferably other carotenoids, in a water-miscible, organic solvents like Isopropanol, ethanol, acetone or tetrahydrofuran mixed with water. When choosing the appropriate proportions of water and organic solvent can either H or J-aggregates are generated. These are characterized by a high light stability out. H aggregates show a "card game-like" stacking molecules, J aggregates have a linear arrangement that resembles a head-to-tail linkage. Leave H units compared to the monomeric form by a hypsochromic shifted Absorbitonsbande in the UV / Vis spectrum, J aggregates through a bathocrome shift prove. On the basis of these Absorbtionsunterschiede can be the Differentiate aggregates and determine their quantitative ratio.

vesicles

One Another object of the present invention are vesicles, the at least one of the compounds (V), preferably 3,3'-dihydroxyisorenieratin contain. The vesicles can using one or more of the compounds (V), Mixtures (M1) or (M2) and / or the colorants according to the invention, Preparations or carotenoid formulations have been prepared be and can for the Preparation of antioxidants, mixtures (M1) or (M2), colorants, Preparations, carotenoid formulations, dermocosmetics, pharmaceuticals, Food or feed or solids and liquids or mixtures thereof.

The Type and amount of compounds used (V) and possibly existing other vesicle components depends on the respective purpose the vesicle. It goes without saying that for vesicles that are essential for food other requirements apply than for vesicles, the for technical dispersions are used. Will the vesicles be in Applications for to the people or for Animals used, for example, in dermocosmetics, pharmaceuticals or food and feed, so should only such others Vesicle components used for human and / or animal consumption or for use in dermocosmetics or pharmaceuticals.

When other vesicle components are suitable substances and mixtures for example, emulsifiers, dispersants, other carotenoids, other antioxidants, peroxide decomposers, radical decomposers, vitamins, polymers,

The Vesicles consist of a hydrophobic sphere in a hydrophilic environment. These spheres can be homogeneous be or consist of one or more hydrophobic layers, which enclose a hydrophilic core and possibly with each other are separated from a hydrophilic layer. The other vesicle components can it is in the hydrophobic layer or in the hydrophilic layer or partially in the hydrophobic or hydrophilic layer. Partial means here partly in relation to the quantity as also the individual molecule of the vesicle component. Vesicle components may also be preferred or exclusively stay in one or several specific layers of the vesicles, for example, vesicles are possible the one or more vesicle components only in their hydrophilic Interior or in one or more hydrophilic interlayers contained in any combination of these.

The Vesicles according to the invention can in different ways known to those skilled in the art and using made of different methods known in the art per se become. The compounds (V) can in the vesicles as monomers, dimers, trimers, tetramers or in H and J aggregates occur. The ratio of the respective monomers, Dimers, trimers, tetramers or in H and J aggregates depend on the particular compound and of other parameters such as temperature or composition of the solvent or the lipid phase and can by influencing these factors to be changed. This allows the ratio of monomer, dimer, trimer, tetramer or the H and J aggregates the other monomers, dimers, trimers, tetramers or H and J-aggregates of 0 wt .-% up to 100 wt .-%, based on the total weight of the respective Connection, waver. For example, 3,3'-dihydroxyisorenierate is in vesicles Phospholipid layers are preferred in the phospholipid layers and there preferably in H-aggregates.

A possibility Producing vesicles is one or more of the compounds (V) in a mixture of one or more organic / approtic solvents with a mixture of lipids in one or more organic / approtic solvents to mix and then to dry. The resulting film can be overcoated with a buffer solution, treated with ultrasound and then extruded. hereby can Vesicles with different structure and size can be produced. The vesicles can Hereby one layer (unilamellar vesicles) or more Layers (multilamellar vesicles) exist

Carotenoid formulations

One further subject of the invention are carotenoid formulations, containing one or more compounds of compounds (V). The compounds (V) or mixtures thereof may be in the form of an antioxidant according to the invention, the mixtures (M1) or (M2), preparations according to the invention, colorants or vesicles contained in the carotenoid formulations or for their use have been used.

Prefers the carotenoid formulations contain 3,3'-dihydroxyisorenieratin, 3,3'-dihydroxyisorrenieratin-1-quinone and 3,3'-dihydroxy-2,2 ', 4,4'-tetra-tert-butylisorenieratin-1-quinone, more preferably 3,3'-dihydroxyisorenieratin and 3,3'-dihydroxyisorrenieratin-1-quinone, most preferably 3,3'-dihydroxyisorenieratin. Preferably, the compounds (V) are enriched and especially preferably in pure form and most preferably in crystalline Form for the preparation of the carotenoid formulations according to the invention used.

The Carotenoid formulations can other carotenoid formulation ingredients which are preferred for human or animal consumption are suitable. Carotenoid formulation Bestanteile can For example, further antioxidants, other carotenoids, preferred natural Carotenoids such as β-carotene, Lycopene or lutein, vitamins, coenzyme compounds, Amino acids, Minerals, enzymes, garlic components, allithiamines, glutathione and its esters, such as GSH monomethyl ester, GSH dimethyl ester, GSH monoethyl ester, GSH diethyl ester or oils, fats or waxes included. Among the fats, the fatty acids are beneficial, preferred are unsaturated fatty acids and more preferably polyunsaturated fatty acids, or Mixtures of these. Among the oils are the physiological ones approved oils prefers.

links with coenzyme character, for example, choline chloride, carnitine, Taurine, creatine, ubiquinone, S-methylmethionine or S-adenosylmethionine.

ingredients of garlic diallyl thiosulfate, S-allyl cysteine sulfoxide, vinyl dithiine, Ajoene, allithiamine such as benfotiamine, fursultiamine, octothiamin or Bentiamin.

Multiple unsaturated fatty acids represent a group within the fats and are, for example, linoleic acid, linolenic acid, arachidonic acid, eicosapentaenoic acid, docusahexaenoic acid.

physiological approved oils represent a group within the oils and are oils such as sesame oil, corn oil, cottonseed oil, soybean oil, peanut oil, esters medium-chain vegetable fatty acids and fish oils such as mackerel, Sprat or salmon oil.

Of the Amount of additional Carotenoid formulation ingredients in the carotenoid formulations in the range of 0.01 to 40 wt .-%, preferably 0.1 to 30 wt .-%, particularly preferably at 0.5 to 20 wt .-%.

Further Carotenoid formulation ingredients may include, for example, protective colloids, Be plasticizers, emulsifiers or mixtures of these. The ratio of Protective colloid and plasticizer to carotenoid is generally so selected that a formulation is obtained as the end product, in addition to the above Carotenoids 10 to 50 wt .-% of a Schutzkoloids, 20 to 70 wt .-% of a plasticizer and optionally subordinate Quantities of a stabilizer, such as another antioxidant contains. The Weight percentages refer to the dry mass of each Carotenoid formulation.

The Compounds (V) or mixtures thereof can be used in the carotenoid formulations according to the invention as a component with great Quantity or with low proportion occur. They lie with high proportion before, so can For example, as a cell-protecting Serve dietary supplements, if they are present at a low level, they can, for example, be the other components of the formulation prior to oxidative reactions protect. The amount of the individual constituents of the carotenoid formulation according to the invention may vary widely depending on the purpose of the carotenoid formulation. As a rule, the proportions of the respective components are in a range of 0.05 to 100 wt .-% based on the total weight the carotenoid formulation. Are β-carotene, lycopene or lutein in the carotenoid formulation, so should the proportion of the Compounds (V) each clearly different from the proportion of β-carotene, lycopene or lutein. Clearly different here means one Amount of at least 10%, preferably at least 20%, especially preferably at least 30% and most preferably at least 40% bigger or at least 10%, preferably at least 20%, more preferably at least 30% and most preferably at least 40% smaller is the biggest or smallest amount of substances β-carotene, Lycopene or lutein.

The Carotenoid formulations can in liquid or in solid form. Preferably, they are in gelatin, particularly preferred in soft gelatin capsules. The production of such Gelatin or soft gelatin capsules are known to the person skilled in the art.

dermocosmetics:

One Another object of the invention are dermocosmetics containing a or more of the compounds (V), antioxidants of the invention, mixtures (M1) or (M2), preparations, colorants, Vesicles or carotenoid formulations contain or under their Use have been made.

The dermocosmetics according to the invention can be different kind. Among them are skin-cosmetic, dermatological or hygienic means of various kinds to understand. Dermocosmetics can For example, W / O or O / W skin and body creams, day and night creams, Eye Creams, Sunscreens, After Sun Products, Hand Care Products, Face creams, multiple emulsions, jellies, microemulsions, liposome preparations, Niosomenpräparate, Anti-wrinkle creams, facial oils, Lipogels, sports gels, moisturizing creams, bleaching creams, vitamin creams, Skin lotions, body lotions, ampoules, aftershave lotions, pre-shaves, moisturizing lotions, Tanning lotions, Cellulite creams, depigmenting agents, massage preparations, Body powder, Facial Toner, Facial Masks, Deodorants, Antiperspirants, Nose Strips, Anti-Acne, Repellent, Shaving, Hair Removal, Intimate care products, foot care products, Baby care products.

Prefers dermocosmetic formulations in the form of ointments, creams, Hydrogels, pastes or patches, as well as liquid dosage forms, such as solutions, Emulsions, in particular oil-in-water emulsions, Suspensions, for example lotions. If you wish too Liposomes or microspheres be used. You can but also in the form of a solid pencil, an aerosol, one Sprays (pump spray or aerosol), foams, gels, gel sprays, lotion, Cream, mousse, ointment, suspension or powder or an oily system or a surfactant preparation for cleaning the skin and / or hair be. Other forms of dermocosmetic preparations for cleaning of skin and hair, for example Bar soaps, Toilet soaps, core soaps, transparent soaps, luxury soaps, Cream Soaps, Baby Soaps, Skin Soaps, Abrasive Soaps, Syndets, liquid Soaps, pasty Soaps, greases, washing pastes, liquid washing, shower and bath preparations z. As washing lotions, shower baths, Shower gels, bubble baths, Cream baths, oil baths, bath extracts, Scrubpräparate, in situ products, shaving foams, Shaving lotions, shaving creams.

in the According to the invention, make-up products are also used in dermocosmetics in cosmetics, hair dyeing or hair care preparations, preparations for oral, dental or dental prostheses and perfumes counted.

The Dermocosmetics can advantageous for the treatment of cosmetic or dermatological changes skin, such as skin aging, loss of skin moisture, the loss of skin elasticity, the formation of wrinkles or wrinkles or pigmentation disorders or Age spots are used. Furthermore, they can be used for treatment or Prevention of unwanted changes of the complexion, such as acne or oily skin, keratoses, rosaceae or photosensitive, flammable, erythematous, allergic or autoimmune-reactive reactions and the like changes be used. The antioxidants of the invention are preferred or mixtures in dermocosmetics for rejuvenation and / or revitalization the skin used. However, the dermocosmetics according to the invention are used also for the soothing of sensitive and irritated skin, for preventive Regulation of collagen, hyaluronic acid, elastin synthesis, stimulation DNA synthesis, especially in deficient or hypoactive skin conditions, regulation of Transcription and translation of matrix-degrading enzymes, in particular Matrix metalloproteases (MMPs) increase cell renewal and regeneration of the skin, increasing the skin's protective and Repair mechanisms for DNA, lipids and / or proteins. These are improvements, for example in the moisture state and / or in the elasticity of the skin, to record

The Dermocosmetics can continue for cleaning the skin or hair or both. They are then preferably in liquid or solid form and in addition to an antioxidant of the invention or mixture, preferably at least one anionic, nonionic or amphoteric surfactant Substance or mixtures thereof, if desired one or more Electrolytes and auxiliaries as commonly used become. The surface active Substance can be in a concentration between 1 and 94 wt .-% in the cleaning preparations are present, based on the total weight the preparations.

The dermocosmetics may not be prescription or prescription. Dermatological preparations are usually prescription. Under dermatological preparations medicines for the therapy or prophylaxis of diseases of the skin (dermatoses) ver stood. The dermatological preparations may be for the treatment of single or multiple possibly related disorders such as anomalies or diseased skin conditions. In the preparations according to the invention, individual active ingredients and excipients or combinations of active ingredients and excipients may be present. Particularly suitable are preparations for the treatment of disorders that are due to oxidative processes.

The dermocosmetics according to the invention can dermocosmetic active ingredients and adjuvants, as they usually be used in such preparations, for. B. preservatives, Bactericides, perfume oils, substances for preventing foaming, Dyes, pigments that are a coloring Have effect, thickener, moisturizing and / or moisturizing Substances, fats, oils, Waxes, softeners, surface-active Substances, emulsifiers, softening substances or other common ingredients a dermocosmetic formulation such as alcohols, polyols, polymers, Foam stabilizers, electrolytes, organic solvents, solubilizers, organic acids, or silicone derivatives.

The Dermocosmetics can in addition to one or more compounds (V), antioxidants according to the invention, Mixtures (M1) or (M2), preparations colorants, vesicles or carotenoid formulations and possibly existing dermocosmetic agents and auxiliaries additional Contain substances that have penetration properties and thus allow rapid penetration into the skin. On the other hand is for applications with "preconditioning" character a fast Penetration usually unimportant, but the ability to deposit in the skin build up, beneficial.

dermocosmetics can to one or more possibly existing dermocosmetic effects and adjuvants may contain at least one other, which is preferably selected among antifungals, antiseptics, antibiotics, sulfonamides, disinfectants, Corticoids, shale oil and tar sulphonates, adstents, antihidrotic agents, antidotes Acne, psoriasis, seborrhea and itching, keratolytics etc.

to Production of dermocosmetics according to the invention can the dermocosmetic active ingredients and excipients with a suitable Excipient mixed or diluted become. Excipients can solid, or more or less liquid Be materials that act as a vehicle, carrier or medium for the drug can serve. The addition of other dermocosmetic active ingredients and excipients if desired in the manner known to those skilled in the art.

und

Hydroxysäuren, Ceramide, antiinflammatorischen, antimikrobiellen oder UV-filternden Substanzen, ethoxylierte Öle ausgewählt aus der Gruppe der ethoxylierten Glycerin-Fettsäureester, Verdickungsmittel, Emulgatoren, Tensiden, Konservierungs mitteln, Parfümölen, Verdickern, Haarpolymeren, Haar- und Hautconditionern, Pfropfpolymeren, wasserlöslichen oder dispergierbaren silikonhaltigen Polymeren, Polysorbate, Lichtschutzmitteln, Bleichmitteln, Gelbildnern, Pflegemitteln, Färbemitteln, Tönungsmitteln, Bräunungsmitteln, Farbstoffen, Pigmenten, Konsistenzgebern, Feuchthaltemitteln, Rückfettern, Collagen, Eiweißhydrolysaten, Lipiden, Antioxidantien, Entschäumern, Antistatika, Emollienzien und Weichmachern, Gleitmittel, Netzmittel, emulgierende und suspendierende Mittel, konservierende Mittel, Antireizstoffe, Chelatbildner, Emulsionsstabilisatoren, Filmbildner, Gelbildner, Geruchsmaskierungsmittel, Harze, Hydrokolloide, Lösemittel, Lösungsvermittler, Neutralisierungsmittel, Permeationsbeschleuniger, Pigmente, quaternäre Ammoniumverbindungen, Rückfettungs- und Überfettungsmittel, Salben-, Creme- oder Öl-Grundstoffe, Silikonderivate, Stabilisatoren, Sterilantien, Treibmittel, Trocknungsmittel, Trübungsmittel, Verdickungsmittel, Wachse, Weichmacher, Weißöle. Eine diesbezügliche Ausgestaltung beruht auf fachmännischem Wissen, wie Sie beispielsweise in Fiedler, H.P. Lexikon der Hilfsstoffe für Pharmazie, Kosmetik und angrenzende Gebiete, 4. Aufl., Aulendorf: ECV-Editio-Kantor-Verlag, 1996 , dargestellt sind. Weiterhin können die Wirk- und Hilfsstoffe ausgewählt sein aus der Gruppe der natürlichen oder synthetischen Polymere, Pigmente, Feuchthaltemittel, Öle, Wachse, Enzyme, Mineralien, Farbstoffe, Duftstoffe, sowie deren Derivaten und Mischungen daraus.The dermocosmetics may contain, in addition to the said dermocosmetic agents and excipients, further compounds which are radically decomposing, peroxide decomposing, anti-erythematous, antiinflammatory or antiallergic in order to supplement or enhance their action. In particular, these compounds can be selected from the group of vitamins, plant extracts,

and

Hydroxy acids, ceramides, anti-inflammatory, antimicrobial or UV-filtering substances, ethoxylated oils selected from the group of ethoxylated glycerol fatty acid esters, thickeners, emulsifiers, surfactants, preservatives, perfume oils, thickeners, hair polymers, hair and skin conditioners, graft polymers, water-soluble or dispersible silicone-containing polymers, polysorbates, light stabilizers, bleaching agents, gelling agents, care agents, colorants, tinting agents, tanning agents, dyes, pigments, bodying agents, humectants, refills, collagen, protein hydrolysates, lipids, antioxidants, defoamers, antistatic agents, emollients and plasticizers, lubricants, wetting agents, emulsifying and suspending agents, preservatives, anti-irritants, chelating agents, emulsion stabilizers, film formers, gellants, odor masking agents, resins, hydrocolloids, solvents, solubilizers, neutralizing agents, perme anion accelerators, pigments, quaternary ammonium compounds, lipid and superfatting agents, ointment, cream or oil bases, silicone derivatives, stabilizers, sterilants, blowing agents, drying agents, opacifiers, thickeners, waxes, plasticizers, white oils. A related design based on expert knowledge, as you for example in Fiedler, HP Lexicon of Excipients for Pharmacy, Cosmetics and Adjacent Areas, 4th ed., Aulendorf: ECV Editio-Kantor-Verlag, 1996 , are shown. Furthermore, the active ingredients and excipients may be selected from the group of natural or synthetic polymers, pigments, humectants, oils, waxes, enzymes, minerals, dyes, fragrances, and derivatives thereof and mixtures thereof.

Polysorbate become advantageous according to the invention in a concentration of 0.1 to 5 wt .-% and in particular in a concentration of 1.5 to 2.5 wt .-%, based on the total weight the composition individually or as a mixture of several polysorbates, used.

The Dermocosmetics can additionally to the antioxidants of the invention contain more antioxidants.

The Amount of other antioxidants (one or more compounds) in the dermocosmetics amounts preferably from 0.001 to 30% by weight, particularly preferably from 0.05 to 20 Wt .-%, in particular 1 to 10 wt .-%, based on the total weight the preparation.

Provided Vitamin E and / or derivatives thereof or the other antioxidants represent, it is advantageous their respective concentrations from the range of 0.001-10 Wt .-%, based on the total weight of the dermocosmetic or pharmaceutical preparation, to choose. If vitamin A or Vitamin A derivatives or other carotenes or derivatives thereof or the antixoidants, it is advantageous to their respective Concentrations in the range of 0.001-10 wt .-%, based on the Total weight of dermocosmetic to choose.

In an embodiment the use of the antioxidants according to the invention, mixtures (M1) or (M2), preparations, colorants, Vesicles or carotenoid formulations or according to the inventive method prepared antioxidants, mixtures (M1) or (M2), preparations, dye, Vesicles or carotenoid formulations with at least one particulate substance, in the composition in a proportion of 0.01 to 10, preferably from 0.05 to 5% by weight. Suitable substances are for. B. substances, at room temperature (25 ° C) are solid and in the form of particles. Suitable are, for example, silica, Silicates, aluminates, clays, mica, salts, especially inorganic Metal salts, metal oxides, e.g. As titanium dioxide, minerals and polymer particles. The particles are in the means undissolved, preferably stably dispersed Form and can after application to the surface of the application and evaporation of the solvent deposit in solid form. Preferred particulate substances are silica (silica gel, Silica) and metal salts, especially inorganic metal salts, with silica being particularly preferred. Metal salts are z. B. alkali or alkaline earth halides such as sodium chloride or potassium chloride; Alkali or alkaline earth sulfates such as sodium sulfate or magnesium sulfate.

The Dermocosmetics can a lipid phase and an aqueous one Phase included.

• – Mineralöle, Mineralwachse
• – Öle, wie Triglyceride der Caprin- oder der Caprylsäure, vorzugsweise aber Rizinusöl;
• – Fette, Wachse und andere natürliche und synthetische Fettkörper, vorzugsweise Ester von Fettsäuren mit Alkoholen niedriger C-Zahl, z. B. mit Isopropanol, Propylenglykol oder Glycerin, oder Ester von Fettalkoholen mit Alkansäuren niedriger C-Zahl oder mit Fettsäuren; Alkylbenzoate;
• – Silikonöle wie Dimethylpolysiloxane, Diethylpolysiloxane, Diphenylpolysiloxane

sowie Mischformen daraus.The lipid phase can advantageously be selected from the following substance group:

• - mineral oils, mineral waxes
• - Oils, such as triglycerides of capric or caprylic, but preferably castor oil;
• Fats, waxes and other natural and synthetic fats, preferably esters of fatty acids with lower C-number alcohols, e.g. With isopropanol, propylene glycol or glycerol, or esters of fatty alcohols with alkanoic acids of low C number or with fatty acids; benzoates;
• - Silicone oils such as dimethylpolysiloxanes, diethylpolysiloxanes, diphenylpolysiloxanes

and mixed forms thereof.

The oil phase of Emulsions, oleogels or hydrodispersions or lipodispersions in the context of the present invention is advantageously selected the group of esters from saturated and / or unsaturated, branched and / or unbranched alkanecarboxylic acids of a chain length of 3 to 30 carbon atoms, from the group of esters of aromatic carboxylic acids and saturated and / or unsaturated, branched and / or unbranched alcohols of a chain length of 3 to 30 carbon atoms. Such ester oils can then chosen advantageous are from the group isopropyl myristate, isopropyl palmitate, isopropyl stearate, Isopropyl oleate, n-butyl stearate, N-hexyl laurate, N-decyl oleate, isooctyl stearate, isononyl stearate, Isononylisnoanoal, 2-ethylhexyl palmitate, 2-ethylhexyl laurate, 2-hexyldecylesterate, 2-octyl dodecyl palmitate, oleyl oleate, oleyl erucate, erucyl oleate, erucyl erucate as well as synthetic, semi-synthetic and natural mixtures of such esters, z. B. jojoba oil.

Further can the oil phase chosen favorably are from the group of branched and unbranched hydrocarbons and waxes, the silicone oils, the dialkyl ether, the group of saturated or unsaturated, branched or unbranched alcohols, as well as the fatty acid triglycerides, namely the triglycerol esters of saturated and / or unsaturated branched and / or unbranched alkanecarboxylic acids of a chain length of 8 to 24, in particular 12 to 18 carbon atoms. The fatty acid triglycerides can for example, advantageously chosen are selected from the group of synthetic, semi-synthetic and natural oils, e.g. B. Olive oil, Sunflower oil, Soybean oil, Peanut oil, rapeseed oil, almond oil, palm oil, coconut oil, palm kernel oil, and the like.

Also any mixtures of such oil and wax components are advantageous in the sense of the present Use invention. It may also be advantageous if Waxes, for example cetyl palmitate, as the sole lipid component the oil phase use.

Advantageously, the oil phase is selected from the group consisting of 2-ethylhexyl isostearate, octyldodecanol, isotridecyl isononanoate, isoeicosane, 2-ethylhexyl cocoate, C ₁₂ -C ₁₅ alkyl benzoate, caprylic capric acid triglyceride, dicapryl ether.

Particularly advantageous are mixtures of C ₁₂ -C ₁₅ -alkyl benzoate, 2-ethylhexyl isostearate and isotridecyl isononanoate.

From The hydrocarbons are paraffin oil, squalane and squalene advantageous to be used in the sense of the present invention.

Advantageous can the oil phase also have a content of cyclic or linear silicone oils or Completely from such oils although it is preferred, except the silicone oil or silicone oils additional Content of other oil phase components to use.

Advantageous Cyclomethicone (Octamethylcyclotetrasiloxan) is used as a silicone oil to be used according to the invention. But also other silicone oils are advantageous for the purposes of the present invention to use for example, hexamethylcyclotrisiloxane, polydimethylsiloxane, poly (methylphenylsiloxane).

Especially furthermore advantageous are mixtures of cyclomethicone and isotridecylisonnanoate, from cyclomethicone and 2-ethylhexyl isostearate.

The aqueous Phase of the dermocosmetics according to the invention contains possibly advantageous

alcohols, Diols or polyols of low C number, and their ethers, preferably Ethanol, isopropanol, propylene glycol, glycerol, ethylene glycol, ethylene glycol monoethyl or -monobutyl ether, propylene glycol monomethyl, -monoethyl- or monobutyl ether, diethylene glycol monomethyl or monoethyl ether and analogous products, and in particular one or more thickeners, which or which can be chosen advantageously from the group silicon dioxide, aluminum silicates, polysaccharides or their derivatives, eg. Hyaluronic acid, Xanthan gum, hydroxypropyl methylcellulose, particularly advantageous from the group of polyacrylates, preferably a polyacrylate from the Group of so-called carbopols, for example carbopols of the types 980, 981, 1382, 2984, 5984, each alone or in combination.

The active ingredients and excipients may also be in encapsulated form as in the patents / patent applications EP 00974775 B1 . DE 23 11 712 . EP 02 78 878 . DE 19 99 47 147 . EP 0706822B1 and WO 98/16621 which is hereby incorporated by reference, may be contained in the preparations according to the invention.

If desired, can several dermocosmetic agents and excipients are formulated together. You can but also first processed separately and then merged.

The Formulation basis of dermocosmetics according to the invention preferably contains one or more cosmetically acceptable media, cosmetically compatible Substances and possibly pharmaceutically acceptable active ingredients and adjuvants. Pharmaceutically acceptable are those in the field of pharmacy, the Food technology and adjacent areas known to be usable Active ingredients and excipients, in particular those in relevant pharmacopoeias (z. B. DAB Ph. Eur. BP NF) listed and other active ingredients and excipients, whose properties do not conflict with a physiological application.

The Dermocosmetics can preferred in individuals, preferably mammals, especially humans, Useful or domestic animals are used. They are applied in for the respective preparation usual Wise. Dermocosmetics are usually enough in one effective amount and preferably transdermally (topically) applied.

To a preferred embodiment If the application according to the invention takes place, of dermocosmetics, by regular application over a Time span. This depends on the desired goal, d. H. the time span can be over extend the lifetime of the user, preferably via a Period of time up to three months and more preferably over one Week to two months, if the goal is a depot in the skin build. For An after-sun application is considered as application period in the sense of the invention the one-time application, but preferably a period of at least one day, more preferably over three days to three months, especially preferred over one to two weeks.

The Antioxidants of the invention or mixtures, colorants, Vesicles or carotenoid formulations can be used to reduce of damage, for example, the skin or hair due to endogenous or exogenous oxidative processes, and secondly for protection of oxidation-sensitive substances and thus for stabilization contribute to the respective preparation. Stabilization affects this both the protection against harmful Oxidation processes, as well as, for example, the protection against microbial Decay.

A Stabilization is in this case compared to preparations without concentrations according to the invention on antioxidant according to the invention or mixtures, colorants, Vesicles or carotenoid formulations, otherwise identical Composition and the same load longer usability of the preparations or also a prevention or reduction of spoilage or inactivation the light and / or oxidation-sensitive dermocosmetic agents or excipients or other ingredients of the dermocosmetic, as a result of z. B. light-induced oxidation damage.

The dermocosmetics according to the invention usually contain 0.01 to 30 wt.%, Preferably 0.01 wt.% To 15% by weight, particularly preferably 0.05 to 5% by weight, very particularly preferably 0.1 to 2% by weight of the antioxidant of the invention, mixtures (M1) or (M2), preparation, colorants, Vesicles or carotenoid formulations based on total weight dermocosmetic.

Possibly becomes the antioxidant (s) according to the invention, Mixtures (M1) or (M2), preparations, colorants, vesicles or carotenoid formulations used with other active ingredients and excipients in encapsulated form, z. As cellulose encapsulation, in gelatin, with polyamides, in Niosomes, wax matrices, encapsulated with cyclodextrins or liposomally.

Hair and nail cosmetics

Furthermore the invention relates to the use of the abovementioned antioxidants according to the invention, Mixtures (M1) or (M2), preparations, colorants, vesicles or carotenoid formulations or the according to the inventive method Antioxidants prepared, mixtures (M1) or (M2), preparations, dye, Vesicles or carotenoid formulations in dermocosmetics. Prefers are the antioxidants of the invention, Mixtures, colorants, Vesicles or carotenoid formulations or the according to the inventive method prepared antioxidants, mixtures, colorants, vesicles or carotenoid formulations in combination with (i) cosmetic aids from the field decorative cosmetics, (ii) dermocosmetics and (iii) suitable excipients and additives. Preferably these are active substances or auxiliaries and additives to protect the skin, hair and / or fingernails or toenails damage, for the treatment of already occurring damage to the skin, hair and / or Fingernails or toenails and used for the care of skin, hair and / or fingernails or toenails become. These agents are preferably selected from Group of natural or synthetic polymers, pigments, humectants, oils, waxes, Enzymes, minerals, vitamins, sunscreens, dyes, fragrances, Antioxidants, preservatives and / or pharmaceutical agents.

The Use of the above-mentioned antioxidants according to the invention, mixtures (M1) or (M2), preparations, colorants, Vesicles or carotenoid formulations or according to the inventive method prepared antioxidants, mixtures (M1) or (M2), preparations, dye, Vesicles or carotenoid formulations is preferably carried out in skin protection products, skin care products, skin cleansers, Hair protectants, hair care products, hair cleansers, hair dyes, or preparation for the decorative cosmetics, depending on the field of application preferably in Form of ointments, creams, emulsions, suspensions, lotions, as Milk, pastes, gels, foams or sprays are applied.

Suitable auxiliaries and additives for the production of hair cosmetic or skin cosmetic preparations are familiar to the expert and can be found in manuals of cosmetics, for example Schrader, bases and formulations of the cosmetics, Hüthig publishing house, Heidelberg, 1989, ISBN 3-7785-1491-1 , or Umbach, cosmetics: development, production and application of ksometischer means, 2nd extended edition, 1995, Georg Thieme Verlag, ISBN 3 13 712602 9 be removed.

Preferably, the use of the antioxidants according to the invention, mixtures (M1) or (M2), preparations, colorants, vesicles or carotenoid formulations or the antioxidants prepared according to the invention, mixtures (M1) or (M2), preparations, colorants, Vesicles or carotenoid formulations in dermocosmetics in combination with at least one of them those selected from among cosmetically active agents, emulsifiers, surfactants, preservatives, perfume oils, thickeners, hair polymers, hair and skin conditioners, graft polymers, water-soluble or dispersible silicone-containing polymers, pharmaceutically acceptable polymers, sunscreens, bleaches, gelling agents, conditioners, colorants, Toning agents, tanning agents, dyes, pigments, bodying agents, moisturizers, restoats, collagen, protein hydrolysates, lipids, antioxidants, defoamers, antistatic agents, emollients and emollients.

According to the invention is also the use of the antioxidants according to the invention, Mixtures (M1) or (M2), preparations, colorants, vesicles or carotenoid formulations or the according to the inventive method prepared antioxidants, mixtures (M1) or (M2), preparations, dye, Vesicles or carotenoid formulations in combination with sunscreens in dermocosmetics. These dermocosmetic sunscreen compositions serve the cosmetic and / or dermatological light protection, furthermore for the treatment and care of the skin and / or the hair and as a make-up product in decorative cosmetics. These include, for example, sun creams, lotions, milks, oils, balms, gels, lip care and lipsticks, masking creams and Pens, Moisturizers, Lotions, Emulsions, Facial, Body- and hand creams, hair conditioners and conditioners, hair fixatives, styling gels, Hair sprays, deodorant or eye wrinkle creams, tropicals, sunblock, After-sun preparations.

Sun oils are usually mixtures of various oils with one or more sunscreen filters and perfume oils. The oil components are selected according to different cosmetic properties. Oils that give good fat and soft feel, such as mineral oils (eg, paraffin oils) and fatty acid triglycerides (eg, peanut oil, sesame oil, avocado oil, medium chain triglycerides) are mixed with oils that enhance dispersibility and absorption of sun oils improve the skin, reduce the stickiness and make the oil film for air and water vapor (sweat) permeable. These include branched-chain fatty acid esters (eg isopropyl palmitate) and silicone oils (eg dimethylsilicone). When using unsaturated fatty acid-based oils, the antioxidants of the present invention, such as tocopherol, are added to prevent rancidity. Sun oils as anhydrous formulations usually contain no preservatives. Sunmilk and creams are made as oil-in-water (O / W) emulsions and as water-in-oil (W / O) emulsions. Depending on the type of emulsion, the properties of the preparations are very different: O / W emulsions are easily distributed on the skin, they are usually absorbed quickly and are almost always readily washable with water. W / O emulsions are harder to rub in, they make the skin stronger and thus look a bit stickier, but on the other hand they better protect the skin from drying out. W / O emulsions are mostly waterproof. In the case of O / W emulsions, the emulsion base, the selection of suitable light stabilizers and, if appropriate, the use of auxiliaries (eg polymers) determine the degree of water resistance. The bases of liquid and cream-like O / W emulsions are similar in composition to other emulsions customary in skin care. Sunmilk should sufficiently grease the skin dried up by sun, water and wind. They must not be sticky, as this is particularly uncomfortable in the heat and in contact with sand. The light stabilizers are usually based on a carrier which contains at least one oil phase. However, compositions based on water are also possible. Accordingly, oils, oil-in-water and water-in-oil emulsions, creams and pastes, lip balm sticks or fat-free gels are contemplated. Suitable emulsions include O / W macroemulsions, O / W microemulsions or O / W / O emulsions having dispersed in surface form coated titanium dioxide particles, wherein the emulsions by phase inversion technology, according to DE-A-197 26 121 are available.

Usual cosmetic Excipients, as additives can be considered Examples are (co-) emulsifiers, fats and waxes, stabilizers, thickeners, biogenic agents, film formers, fragrances, dyes, pearlescing agents, Preservatives, pigments, electrolytes (eg magnesium sulphate) and pH regulators. As stabilizers, metal salts of fatty acids such as z. As magnesium, aluminum and / or zinc stearate. Biogenic agents include, for example, plant extracts, protein hydrolysates and vitamin complexes. Common film makers are for example Hydrocolloids such as chitosan, microcrystalline chitosan or quaternized Chitosan, polyvinylpyrrolidone, vinylpyrrolidone-vinyl acetate copolymers, Polymers of the acrylic acid series, quaternary Cellulose derivatives and the like Links.

Suitable light-filtering agents are substances that absorb UV rays in the UV-B and / or UV-A range. These are organic substances that are able to absorb ultraviolet rays and the absorbed energy in the form of longer-wave radiation, eg. B. heat, again. The organic substances may be oil-soluble or water-soluble. Suitable UV filters are, for example, 2,4,6-triaryl-1,3,5-triazines in which the aryl groups can each bear at least one substituent, which is preferably selected from hydroxy, alkoxy, especially methoxy, alkoxycarbonyl, especially methoxycarbonyl and ethoxycarbonyl. Also suitable are p-aminobenzoic acid esters, cinnamic acid esters, benzophenones, camphor derivatives and UV-radiation-stopping pigments, such as titanium dioxide, talc and zinc oxide. Particular preference is given to pigments based on titanium dioxide.

As oil-soluble UV-B filter z. B. the following substances are used:
3-benzylidene camphor and its derivatives, e.g. B. 3- (4-methylbenzylidene) camphor;
4-aminobenzoic acid derivatives, preferably 2-ethylhexyl 4- (dimethylamino) benzoate, 2-octyl 4- (dimethylamino) benzoate and 4- (dimethylamino) benzoic acid ester;
Esters of cinnamic acid, preferably 4-methoxycinnamic acid 2-ethylhexyl ester, 4-propyl methoxycinnamate, isoamyl 4-methoxycinnamate, 4-isopentyl methoxycinnamate, 2-cyano-3-phenylcinnamic acid 2-ethylhexyl ester (octocrylene);
Esters of salicylic acid, preferably 2-ethylhexyl salicylate, 4-isopropylbenzyl salicylate, homomenthyl salicylate;
Derivatives of benzophenone, preferably 2-hydroxy-4-methoxybenzophenone, 2-hydroxy-4-methoxy-4'-methylbenzophenone, 2,2'-dihydroxy-4-methoxybenzophenone;
Esters of benzalmalonic acid, preferably di-2-ethylhexyl 4-methoxybenzmalonate;
Triazine derivatives, such as. For example, 2,4,6-trianilino- (p-carbo-2'-ethyl-1'-hexyloxy) -1,3,5-triazine (Octyltriazone) and Dioctyl Butamido Triazone (Uvasorb HEB ^®):
Propane-1,3-diones, such as. B. 1- (4-tert-butylphenyl) -3- (4'-methoxyphenyl) propane-1,3-dione.

Suitable water-soluble substances are:
2-phenylbenzimidazole-5-sulfonic acid and its alkali, alkaline earth, ammonium, alkylammonium, alkanolammonium and glucammonium salts;
Sulfonic acid derivatives of benzophenones, preferably 2-hydroxy-4-methoxybenzophenone-5-sulfonic acid and its salts;
Sulfonic acid derivatives of 3-Benzylidencamphers, such as. B. 4- (2-oxo-3-bomylidenemethyl) benzenesulfonic acid and 2-methyl-5- (2-oxo-3-bomylidene) sulfonic acid and salts thereof.

Especially preferred is the use of esters of cinnamic acid, preferably 4-methoxycinnamic acid 2-ethylhexyl ester, 4-methoxycinnamate, 2-cyano-3-phenyl-cinnamic acid 2-ethylhexyl ester (Octocrylene).

Of Another is the use of derivatives of benzophenone, in particular 2-hydroxy-4-methoxybenzophenone, 2-hydroxy-4-methoxy-4'-methylbenzophenone, 2,2'-dihydroxy-4-methoxybenzophenone and the use of propane-1,3-diones, such as, for example, 1- (4-tert-butylphenyl) -3- (4-methethoxyphenyl) propane-1,3-dione prefers.

Typical UV-A filters are:
Derivatives of benzoylmethane, such as 1- (4'-tert-butylphenyl) -3- (4'-methoxyphenyl) propane-1,3-dione, 4-tert-butyl-4'-methoxydibenzoylmethane or 1-phenyl-3 - (4'-isopropylphenyl) -propane-1,3-dione;
Amino-hydroxy-substituted derivatives of benzophenones such as. N, N-diethylamino-hydroxybenzoyl-n-hexylbenzoate.

The UV-A and UV-B filters can Of course can also be used in combinations.

Further suitable UV filter substances are mentioned in the following table. No. material CAS-No. (= Acid) 1 4-aminobenzoic acid 150-13-0 2 3- (4'-trimethylammonium) -benzylidenbornan-2-one methyl sulfate 52793-97-2 3 3,3,5-trimethyl-cyclohexyl-salicylate (homosalatum) 118-56-9 4 2-hydroxy-4-methoxybenzophenone (oxybenzone) 131-57-7 5 2-phenylbenzimidazole-5-sulfonic acid and its potassium, sodium and. triethanolamine 27503-81-7 6 3,3 '- (1,4-phenylenedimethine) -bis (7,7-dimethyl-2-oxobicyclo [2.2.1] heptane-1-methanesulfonic acid) and its salts 90457-82-2 7 4-bis (polyethoxy) amino-ethyl ester benzoesäurepolyethoxy 113010-52-9 8th 4-dimethylamino-benzoic acid 2-ethylhexyl ester 21245-02-3 9 Salicylic acid 2-ethylhexyl ester 118-60-5 10 4-methoxy cinnamic acid-2-isoamyl 71617-10-2 11 4-methoxy cinnamic acid-2-ethylhexyl 5466-77-3 12 2-hydroxy-4-methoxy-benzophenone-5-sulfonic acid (sulisobenzone) and the sodium salt 4065-45-6 13 3- (4'-sulfobenzylidene) -bornan-2-one and salts 58030-58-6 14 3-benzylidenebornan-2-one 16087-24-8 15 1-4'-isopropylphenyl) -3-phenylpropane-1,3-dione 63260-25-9 16 4-isopropylbenzyl 94134-93-7 17 3-imidazol-4-yl-acrylic acid and its ethyl ester 104-98-3 18 2-cyano-3,3-diphenylacrylate 5232-99-5 19 2-cyano-3,3-diphenylacrylate 2'-ethylhexyl 6197-30-4 20 Menthyl o-aminobenzoate or: 5-methyl-2- (1-methylethyl) -2-aminobenzoate 134-09-8 21 Glyceryl p-aminobenzoate or: 4-aminobenzoic acid 1-glyceryl ester 136-44-7 22 2,2'-dihydroxy-4-methoxybenzophenone (dioxybenzone) 131-53-3 23 2-hydroxy-4-methoxy-4-methylbenzophenone (mexenone) 1641-17-4 24 Triethanolamine salicylate 2174-16-5 25 Dimethoxyphenylglyoxalic acid or: 3,4-dimethoxyphenylglyoxalic acid sodium 4732-70-1 26 3- (4'-sulfobenzylidene) -bornan-2-one and its salts 56039-58-8 27 4-tert-butyl-4'-methoxydibenzoylmethane 70356-09-1 28 2,2 ', 4,4'-tetrahydroxybenzophenone 131-55-5 29 2,2'-methylene-bis- [6- (2H-benzotriazol-2-yl) -4- (1,1,3,3-tetramethylbutyl) phenol] 103597-45-1 30 2,2 '- (1,4-phenylene) -bis-1H-benzimidazole-4,6-disulfonic acid, Na salt 180898-37-7 31 2,4-bis- [4- (2-ethylhexyloxy) -2-hydroxy] phenyl-6- (4-methoxyphenyl) - (1,3,5) triazine 187393-00-6 32 3- (4-methylbenzylidene) -camphor 36861-47-9 33 4-bis (polyethoxy) paraaminobenzoesäurepolyethoxyethylester 113010-52-9 34 2,4-dihydroxybenzophenone 131-56-6 35 2,2'-dihydroxy-4,4'-dimethoxybenzophenone-5,5'-disodium sulfonate 3121-60-6 36 Benzoic acid, 2- [4- (diethylamino) -2-hydroxybenzoyl] -, hexyl ester 302776-68-7 37 2- (2H-benzotriazole-2-yl) -4-methyl-6- [2-methyl-3- [1,3,3,3-tetramethyl-1 - [(trimethylsilyl) oxy] disiloxanyl] propyl] phenol 155633-54-8 38 1.1 to 1.3-butadiene -4,4-diphenyl-[(2,2-dimethylpropoxy) carbonyl] 363602-15-7 Table 4: suitable sunscreens

Next The two aforementioned groups of primary photoprotective agents can also secondary Sunscreens of the antioxidant type are used, which interrupt the photochemical reaction chain that is triggered when UV radiation penetrates the skin. Typical examples are superoxide dismutase, Catalase, tocopherols (vitamin E) and ascorbic acid (vitamin C).

A Another group are anti-irritants that are anti-inflammatory Effect on damaged by UV light Own skin. Such substances are, for example, bisabolol, phytol and phytantriol.

Also according to the invention is the use of the antioxidants according to the invention, mixtures, colorants, vesicles or carotenoid formulations or the antioxidants prepared according to the process of the invention, mixtures, colorants, vesicles or carotenoid formulations in combination with UV-blocking inorganic pigments in dermocosmetics. Preference is given to pigments based on metal oxides and / or other sparingly water-soluble or insoluble metal compounds selected from the group of the oxides of zinc (ZnO), titanium (TiO ₂ ), iron (eg Fe ₂ O ₃ ), zirconium (ZrO ₂ ), silicon (SiO ₂ ), manganese (eg MnO), aluminum (Al ₂ O ₃ ), cerium (eg Ce ₂ O ₃ ), mixed oxides of the corresponding metals and mixtures of such oxides.

The inorganic pigments can be present in coated form, ie they are treated on the surface. This surface treatment can be, for example, that the pigments in a conventional manner, as in DE-A-33 14 742 described, are provided with a thin hydrophobic layer.

Further preferred are so-called peroxide decomposed, i. Connections the are capable of peroxides, more preferably lipid peroxides too decompose. These include organic substances, such as. Pyridine-2-thiol-3-carboxylic acid, 2-Methoxy-pyrimidinol-carboxylic acids, 2-methoxy-pyridinecarboxylic acids, 2-dimethylaminopyrimidinolcarboxylic acids, 2-dimethylaminopyridinecarboxylic acids.

The amount of the mocosmetic active ingredients (one or more compounds) in the preparations according to the invention is preferably 0.001 to 30 wt .-%, particularly preferably 0.05 to 20 wt .-%, in particular 1 to 10 wt .-%, based on the Total weight of the preparation. The above and other active substances which can be used in the preparations according to the invention are described in US Pat DE 103 18 526 A1 on pages 12 to 17, to which reference is made in its entirety.

In a preferred embodiment of the present invention contain dermocosmetics Skin and hair treatment agents, the antioxidants of the invention, Mixtures (M1) or (M2), preparations, colorants, vesicles or carotenoid formulations or according to the inventive method prepared antioxidants, mixtures (M1) or (M2), preparations, dye, Vesicles or carotenoid formulations in a concentration of 0.001 to 1% by weight, preferably 0.01 to 0.9% by weight, especially preferably 0.01 to 0.8 wt .-% or 0.01 to 0.7 wt .-%, very particularly preferably 0.01 to 0.6 wt.% or 0.01 to 0.5 wt.%, most preferably 0.01 to 0.4 wt .-% or 0.01 to 0.3 wt .-% based on the total weight of the agent. In a further embodiment the agents contain antioxidants, mixtures according to the invention (M1) or (M2), preparations, colorants, Vesicles or carotenoid formulations or according to the inventive method prepared antioxidants, mixtures (M1) or (M2), preparations, dye, Vesicles or carotenoid formulations in a concentration of 1 to 10 wt .-%, preferably 2 to 8 wt .-%, 3 to 7 wt .-%, 4 to 6 wt .-% based on the total weight of the composition. In a also preferred embodiment the agents contain antioxidants, mixtures according to the invention (M1) or (M2), preparations, colorants, Vesicles or carotenoid formulations or according to the inventive method prepared antioxidants, mixtures, colorants, vesicles or carotenoid formulations in a concentration of 10 to 20% by weight, preferably 11 to 19% by weight, 12 to 18% by weight, 13 to 17% by weight, 14 to 16% by weight based on the total weight of the agent. In a likewise preferred embodiment the agents contain antioxidants, mixtures according to the invention (M1) or (M2), passages, stains, vesicles or carotenoid formulations or the according to the inventive method produced antioxidants, mixtures (M1) or (M2), passages, dye, Vesicles or carotenoid formulations in a concentration of From 20 to 30% by weight, preferably from 21 to 29% by weight, from 22 to 28% by weight, 23 to 27 wt .-%, 24 to 26 wt .-% based on the total weight of the agent.

In addition, the following applies to the dermocosmetics according to the invention:
The formulation base of compositions according to the invention preferably contains dermocosmetically or pharmaceutically acceptable active ingredients or excipients. Pharmaceutically acceptable excipients known to be useful in the pharmaceutical, food technology and related fields, in particular those listed in relevant pharmacopoeias (eg DAB Ph. Eur. BP NF) and other excipients whose properties do not preclude physiological application.

Suitable dermocosmetic or pharmaceutical excipients may include lubricants, wetting agents, emulsifying and suspending agents, preserving agents, antioxidants, anti-irritants, chelating agents, emulsion stabilizers, film formers, gelling agents, odor masking agents, resins, hydrocolloids, solvents, solubilizers, neutralizing agents, permeation enhancers, pigments, quaternary ammonium compounds , Restreasing and superfatting agents, ointment, cream or oil bases, silicone derivatives, stabilizers, sterilants, blowing agents, drying agents, opacifiers, thickeners, waxes, softeners, white oil. A related embodiment is based on expert knowledge, such as in Fiedler, HP Lexicon of Excipients for Pharmacy, Cosmetics and Adjacent Areas, 4th ed., Aulendorf: ECV Editio-Kantor-Verlag, 1996 , are shown.

To prepare the dermocosmetic agents of the invention, the active ingredients may be mixed or diluted with a suitable excipient (excipient). Excipients may be solid, semi-solid or liquid materials which may serve as a vehicle, carrier or medium for the active ingredient. The Zumi If desired, further excipients are carried out in the manner known to the person skilled in the art. Furthermore, the polymers and dispersions are suitable as auxiliaries in pharmacy, preferably as or in coating agent (s) or binder (s) for solid dosage forms. They can also be used in creams and as tablet coatings and tablet binders.

To a further preferred embodiment the dermocosmetics according to the invention are cosmetic Means for the care and protection of the skin and hair, nail care preparations or preparations for the decorative cosmetics.

suitable Dermocosmetics are z. For example, facewash, face masks, deodorants and other cosmetic lotions. Means for use in the decorative Cosmetics include, for example, concealers, theatrical paints, mascara and eyeshadows, lipsticks, kohl pencils, eyeliners, rouges, powders and eyebrow pencils.

Moreover can the microcapsules of the invention or according to the inventive method prepared O / W dispersions are used in nose strips for pore cleaning, in anti-acne products, repellents, shaving products, after- and pre-shave Care products, after-sun care products, hair-removing preparations, hair dyes, Intimate cleansing, foot care and baby care.

The skin cosmetic preparations in addition to the invention above mentioned compounds and suitable carriers nor other common in skin care agents and adjuvants as described above. These are preferably Emulsifiers, preservatives, perfume oils, cosmetic active ingredients such as phytantriol, bisabolol, panthenol, sunscreen, bleach, dye, Tints, Tanning agents, Collagen, protein hydrolysates, stabilizers, pH regulators, colorants, salts, Thickener, gelling agent, bodying agent, silicones, humectants, refatting and / or other conventional additives.

Preferred oil and fat components dermocosmetic dermocosmetics are the aforementioned mineral and synthetic oils, such as Paraffins, silicone oils and aliphatic hydrocarbons having more than 8 carbon atoms, animal and vegetable oils, such as Sunflower oil, Coconut oil, Avocado oil, Olive oil, lanolin, or waxes, fatty acids, fatty acid ester, such as Triglycerides of C6-C30 fatty acids, wax esters such as Z. B. jojoba oil, Fatty alcohols, petrolatum, hydrogenated lanolin and acetylated lanolin and mixtures thereof.

to Setting certain properties such. B. improvement of feel to the touch, the spreading behavior, the water resistance and / or the binding of Active ingredients and excipients, such as pigments, can be used in skin and cosmetic Dermocosmetics additionally also conditioning substances based on silicone compounds contain.

suitable Silicone compounds are, for example, polyalkylsiloxanes, polyarylsiloxanes, Polyarylalkylsiloxanes, polyethersiloxanes or silicone resins.

The Production of skin-cosmetic dermocosmetics takes place according to customary, known to those skilled in the process.

Prefers Skin-cosmetic dermocosmetics are in the form of emulsions especially as a water-in-oil (W / O) - or oil-in-water (O / W) emulsions.

It but it is also possible to choose other types of formulations, for example, gels, oils, Oleogels, multiple emulsions, for example in the form of W / O / W or O / W / O emulsions, Anhydrous ointments or ointment bases, etc. Also emulsifier-free Formulations such as hydrodispersions, hydrogels or a Pickering emulsion are advantageous embodiments.

Emulsions are prepared by known methods. In addition to at least one keratin-binding effector molecule, the emulsions generally contain customary constituents, such as fatty alcohols, fatty acid esters and especially fatty acid triglycerides, fatty acids, lanolin and derivatives thereof, natural or synthetic oils or waxes and emulsifiers in the presence of water. The selection of emulsion type specific additives and the preparation of suitable emulsions is described, for example, in US Pat Schrader, bases and formulations of the cosmetics, Hüthig book publishing house, Heidelberg, 2nd edition, 1989, third part, or Umbach, cosmetics: development, production and application of ksometischer means, 2nd extended edition, 1995, Georg Thieme publishing house, ISBN 3 13 712602 9, pages 122 ff., which is hereby incorporated by reference.

preferred Fats and oils, which may be included in the fat phase of the emulsions are: Hydrocarbon oils, like paraffin oil, purCellin, Perhydrosqualene and solutions microcrystalline waxes in these oils; animal or vegetable oils, such as Sweet almond oil, avocado oil, calophilum oil, lanolin and derivatives thereof, castor oil, Sesame oil, Olive oil, jojoba oil, Shea oil, Hoplostethus oil, mineral oils, whose distillation start under atmospheric pressure at about 250 ° C and their Distillation endpoint at 410 ° C lies, such. B. Vaseline oil, Saturated esters or unsaturated fatty acids, such as alkyl myristates, e.g. B. i-propyl, butyl or cetyl myristate, Hexadecyl stearate, ethyl or i-propyl palmitate, octanoic or decanoic acid triglycerides and cetylricinoleate.

The Fat phase can also be found in other oils soluble Silicone oils, such as dimethylpolysiloxane, methylphenylpolysiloxane and the silicone glycol copolymer, fatty acids and fatty alcohols.

Next the above invention described compounds the dermocosmetics also contain waxes, such as. Carnauba wax, Candililla wax, beeswax, microcrystalline wax, ozokerite wax and Ca, Mg and Al oleates, myristates, linoleates and stearates.

To a further preferred embodiment If the agents according to the invention are a light stabilizer, a shower gel, a shampoo formulation or a bath preparation, wherein Sunscreens are particularly preferred.

Such Formulations contain, in addition to the antioxidants of the invention, mixtures (M1) or (M2), preparations, colorants, Vesicles or carotenoid formulations or according to the inventive method prepared antioxidants, mixtures, colorants, vesicles or carotenoid formulations usually anionic surfactants as base surfactants and amphoteric and / or nonionic Surfactants as cosurfactants. Other suitable active ingredients and / or auxiliaries are generally selected among lipids, perfume oils, dyes, organic acids, Preservatives and antioxidants as well as thickeners / gelling agents, Skin conditioners and moisturizers.

These Formulations preferably contain from 2 to 50% by weight, preferably 5 to 40 wt .-%, particularly preferably 8 to 30 wt .-% surfactants, based on the total weight of the formulation.

In the washing, shower and bath preparations can all in body cleansers usually used anionic, neutral, amphoteric or cationic Surfactants are used.

suitable anionic surfactants are, for example, alkyl sulfates, alkyl ether sulfates, Alkyl sulfonates, alkylaryl sulfonates, alkyl succinates, alkyl sulfosuccinates, N-alkoylsarcosinates, acyltaurates, acylisothionates, alkylphosphates, Alkyl ether phosphates, alkyl ether carboxylates, alpha olefin sulfonates, in particular the alkali and alkaline earth metal salts, eg sodium, Potassium, magnesium, calcium, as well as ammonium and triethanolamine salts.

The Alkyl ether sulfates, alkyl ether phosphates and alkyl ether carboxylates can between 1 to 10 ethylene oxide or propylene oxide units, preferred 1 to 3 ethylene oxide units in the molecule.

To counting z. Sodium lauryl sulfate, ammonium tauryl sulfate, sodium lauryl ether sulfate, Ammonium lauryl ether sulfate, sodium lauryl sarcosinate, sodium oleyl succinate, Ammonium lauryl sulfosuccinate, sodium dodecyl benzene sulfonate, triethanolamine dodecyl benzene sulfonate.

suitable amphoteric surfactants are for. B. alkylbetaines, alkylamidopropyl betaines, Alkylsulfobetaines, alkylglycinates, alkylcarboxyglycinates, alkylamphoacetates or propionates, alkyl amphodiacetates or dipropionates.

For example can Cocodimethyl sulphopropyl betaine, lauryl betaine, cocamidopropyl betaine or sodium cocamphopropionate.

Suitable nonionic surfactants are, for example, the reaction products of aliphatic alcohols or alkylphenols having 6 to 20 C atoms in the alkyl chain, which may be linear or branched, with ethylene oxide and / or propylene oxide. The amount of alkylene oxide is about 6 to 60 moles per mole of alcohol. Fer ner are alkylamine oxides, mono- or dialkylalkanolamides, fatty acid esters of polyethylene glycols, ethoxylated fatty acid amides, alkylpolyglycosides or sorbitan ether suitable.

Moreover can the washing, shower and bath preparations usual cationic Contain surfactants, such as. B. quaternary ammonium compounds, for example Cetyltrimethylammonium chloride.

Farther can the shower gel / shampoo formulations thickeners, such as, for example, common salt, PEG-55, propylene glycol oleate, PEG-120 methyl glucose dioleate and others, as well as preservatives, other active ingredients and auxiliaries and water contain.

Further provide antioxidants according to the invention, Mixtures (M1) or (M2), preparations, colorants, vesicles or carotenoid formulations in hair cosmetic preparations protection against premature Aging processes of human hair and can thus, for example, as Active ingredients in the cosmetic treatment of brittle, lackluster and inelastic hair are used.

at Dermocosmetics for the protection of hair according to the invention is For example, to shampoo, dermocosmetics, the when rinsing hair before or after shampooing, before or after perming, before or after staining or discoloration The hair can be applied to the blow dryer or to the mocosmetics Inserting the hair, dermocosmetics for dyeing or decolorization, to a hairdressing and treatment lotion, a hair coat or perming agent.

Suitable auxiliaries and additives for the production of dermocosmetics for the protection of the hair are familiar to the person skilled in the art and can be obtained from manuals of cosmetics, for example Schrader, bases and formulations of cosmetics, Hüthig Verlag, Heidelberg, 1989, ISBN 3-7785-1491-1, or Umbach, cosmetics: development, production and application of ksometischer means, 2nd edition, 1995, Georg Thieme Verlag, ISBN 3 13 712602 9 be removed.

The Dermocosmetics for the protection of hair contain active substances and adjuvants, as they usually do For this Type of dermocosmetics used for hair care and hair treatment become. Active ingredients and auxiliaries are, for example, preservatives, surfactants Substances, substances for preventing foaming, thickening agents, emulsifiers, Fats, oils, Waxes, organic solvents, Bactericides, perfumes, Dyes or pigments, whose function is the hair or the cosmetic and dermatological preparations for the protection of To dye hair yourself, Electrolytes or substances against the greasing of the hair.

Under Electrolytes in the sense of the present invention are water-soluble alkali, Ammonium, alkaline earth (including magnesium) and zinc salts inorganic anions and any mixtures of such salts to understand, being guaranteed must be that these salts by pharmaceutical or cosmetic Safety.

The Anions according to the invention are preferred from the group of chlorides, sulfates and hydrogen sulfates, the Phosphates. Hydrogen phosphates and the linear and cyclic oligophosphates as well the carbonates and bicarbonates.

Lie the dermocosmetics protect the hair in the form of a lotion, the rinsed out and Z. B. before or after decolorization, before or after shampooing, between two shampooing steps or after the permanent wave treatment is applied, it is itself thereby z. B. aqueous or aqueous-alcoholic solutions, the optionally surface-active Contain substances whose concentration is between 0.1 and 10% by weight, preferably between 0.2 and 5 wt .-%, based on the total weight the preparation may be.

A dermocosmetische preparation for the protection of the hair in the form of a Lotion that is not rinsed out is, in particular a lotion for inserting the hair, a lotion, the while blowing hair is used, a hairdressing and treatment lotion, poses in the general an aqueous, alcoholic or watery-alcoholic solution and contains at least one cationic, anionic, nonionic or amphoteric Polymer or else mixtures thereof and / or at least one lignan, selected from the group consisting of secoisolariciresinol, matairesinol, Enterolactone, enterodiol, pinoresinol, syringaresinol, isolaririciresinol and Lariciresinol and their glycosides in effective concentration. The amount of polymers used is z. B. between 0.1 and 10 wt .-%, preferably between 0.1 and 3 wt .-%, based on the Total weight of the preparation.

dermocosmetics for the protection of hair containing antioxidants of the invention, can are present as emulsions, which are non-ionic or anionic Type are. Nonionic emulsions contain, in addition to water, oils or Fatty alcohols, which are also polyethoxylated or polypropoxylated, for example could be, or mixtures of the two organic components. These Emulsions optionally contain cationic surface-active Substances.

According to the invention, dermocosmetics to protect the hair as gels present, in addition to an effective Content of at least one chroman derivative of the formula I and usually used solvents, preferably water, organic thickeners, z. Gum arabic, Xanthan gum, sodium alginate, cellulose derivatives, preferably methylcellulose, Hydroxymethylcellulose, hydroxyethylcellulose, hydroxypropylcellulose, Hydroxypropylmethylcellulose or inorganic thickening agents, z. As aluminum silicates such as bentonites, or a mixture of polyethylene glycol and polyethylene glycol stearate or distearate, contain. The thickening agent is present in the gel Z. B. in an amount between 0.1 and 30% by weight, preferably between 0.5 and 15% by weight.

dermocosmetics to protect the hair, which is a shampoo, in addition to an effective content of antioxidants of the invention preferably at least one anionic, nonionic or amphoteric surfactants Substance or mixtures thereof, optionally an inventive electrolyte and aids, as they usually do used for it become. The surface active Substance can be in a concentration between 1 wt .-% and 94 wt .-% in the shampoo.

• – herkömmliche Seifen, z. B. Fettsäuresalze des Natriums
• – Alkylsulfate, Alkylethersulfate, Alkan- und Alkylbenzolsulfonate
• – Sulfoacetate
• – Sulfobetaine
• – Sarcosinate
• – Amidosulfobetaine
• – Sulfosuccinate
• – Sulfobernsteinsäurehalbester
• – Alkylethercarboxylate
• – Eiweiß-Fettsaure-Kondensate
• – Alkylbetaine und Amidobetaine
• – Fettsäurealkanolamide
• – Polyglycolether-Derivate.

Aqueous dermocosmetics according to the invention, which are detergents or low-water or anhydrous cleaning agent concentrates intended for aqueous cleaning, may contain anionic, nonionic and / or amphoteric surfactants, for example

• - conventional soaps, z. B. fatty acid salts of sodium
• - Alkyl sulfates, alkyl ether sulfates, alkane and alkylbenzenesulfonates
• - Sulfoacetates
• - sulfobetaines
• - sarcosinates
• - amidosulfobetaines
• - sulfosuccinates
• - sulfosuccinic monoesters
• - Alkyl ether carboxylates
• - Protein-fatty acid condensates
• - alkyl betaines and amidobetaines
• - fatty acid alkanolamides
• - Polyglycol ether derivatives.

Preferably are the dermocosmetics according to the invention for the protection of hair in the form of a mousse, hair mousse, Hair gels, shampoos, hair sprays, hair mousse, top fluids, leveling agents for perms, hair coloring and bleach or "hot oil treatments". Depending on the application can the hair cosmetic preparations as (aerosol) spray, (aerosol) foam, Gel, gel spray, cream, lotion or wax can be applied. hairsprays include both aerosol sprays and pump sprays without propellant gas. hair foams include both aerosol foams as well as pump foams without Propellant. Hair sprays and hair foams preferably comprise predominantly or exclusively water-soluble or water-dispersible components. Are those in the hairsprays according to the invention and hair foams water-dispersible compounds used, they can be in the form of aqueous Microdispersions with particle diameters of usually 1 to 350 nm, preferably 1 to 250 nm, are used. The solids content of these preparations usually lie here in a range of about 0.5 to 20 wt%. These microdispersions need usually no emulsifiers or surfactants for their stabilization.

Under other constituents are the additives customary in cosmetics, for example propellants, defoamers, surfactants Compounds, i. Surfactants, emulsifiers, foaming agents and solubilizers. The used surface-active Connections can anionic, cationic, amphoteric or neutral. Other common ingredients can also be z. Preservatives, perfume oils, opacifiers, active ingredients, UV filters, Nursing substances such as panthenol, collagen, vitamins, protein hydrolysates, Alpha and beta hydroxycarboxylic acids, Stabilizers, pH regulators, Dyes, viscosity regulators, gelling agents, Salts, humectants, moisturizers, Complexing agent and other common Additives.

Farther counting this all known in cosmetics styling and conditioner polymers that in Combination with the microcapsules according to the invention or according to the method of the invention prepared O / W dispersions can be used if very special properties should be set.

When conventional Hair cosmetic polymers are, for example, the aforementioned cationic, anionic, neutral, nonionic and amphoteric Polymers to which reference is hereby made.

to Setting certain properties, the preparations may also be Contain conditioning substances based on silicone compounds. Suitable silicone compounds are, for example, polyalkylsiloxanes, Polyarylsiloxanes, polyarylalkylsiloxanes, polyethersiloxanes, silicone resins or dimethicone copolyols (CTFA) and amino functional silicone compounds like amodimethicones (CTFA).

propellant are the for Hairsprays or aerosol foams commonly used Propellant. Preference is given to mixtures of propane / butane, pentane, dimethyl ether, 1,1-difluoroethane (HFC-152a), carbon dioxide, nitrogen or compressed air.

When Emulsifiers can all in hair foams usually used emulsifiers are used. Suitable emulsifiers can nonionic, cationic or anionic or amphoteric. Examples of nonionic Emulsifiers (INCI nomenclature) are Laurethe, z. Laureth-4; Cetethe, z. Cetheth-1, polyethylene glycol cetyl ether, Cetearethe, z. Cetheareth-25, polyglycol fatty acid glycerides, hydroxylated Lecithin, lactyl ester of fatty acids, Alkylpolyglycosides.

Examples for cationic Emulsifiers are cetyldimethyl-2-hydroxyethylammonium dihydrogen phosphate, Cetyltrimonium chloride, cetyltrimmonium bromide, cocotrimonium methylsulfate, Quaternium-1 to x (INCI).

anionic Emulsifiers can for example, selected are selected from the group of alkyl sulfates, alkyl ether sulfates, alkyl sulfonates, Alkylarylsulfonates, alkylsuccinates, alkylsulfosuccinates, N-alkoylsarcosinates, acyltaurates, Acyl isethionates, alkyl phosphates, alkyl ether phosphates, alkyl ether carboxylates, Alpha olefin sulfonates, in particular the alkali and alkaline earth metal salts, z. As sodium, potassium, magnesium, calcium, and ammonium and triethanolamine salts. The alkyl ether sulfates, alkyl ether phosphates and alkyl ether carboxylates can be used between 1 to 10 ethylene oxide or propylene oxide units, preferably 1 to 3 ethylene oxide units in the molecule exhibit.

When Gelbildner can all usual in cosmetics Gel former can be used. These include slightly crosslinked polyacrylic acid, for example Carbomer (INCI), Cellu losederivate, z. Hydroxypropyl cellulose, hydroxyethyl cellulose, cationically modified celluloses, polysaccharides, e.g. Xanthan gum, Caprylic / capric triglyceride, sodium acrylate copolymers, Polyquaternium-32 (and) Paraffin Liquidum (INCI), Sodium Acrylate Copolymers (and) Paraffinum Liquidum (and) PPG-1 trideceth-6, acrylamidopropyltrimonium chloride / acrylamide copolymers, Steareth-10-allyl ether, acrylate copolymers, Polyquaternium-37 (and) Paraffinum Liquidum (and) PPG-1 Trideceth-6, Polyquaternium 37 (and) propylene glycol dicaprate dicaprylate (and) PPG-1 trideceth-6, Polyquaternium-7, Polyquaternium-44.

In the shampoo formulations all in shampoos usually used anionic, neutral, amphoteric or cationic Surfactants are used.

suitable anionic surfactants are, for example, alkyl sulfates, alkyl ether sulfates, Alkyl sulfonates, alkylaryl sulfonates, alkyl succinates, alkyl sulfosuccinates, N-Alkoylsarkosinate, Acyl taurates, acyl isothionates, alkyl phosphates, alkyl ether phosphates, Alkyl ether carboxylates, alpha-olefin sulfonates, in particular the alkali metal and alkaline earth metal salts, e.g. As sodium, potassium, magnesium, calcium, and ammonium and triethanolamine salts. The alkyl ether sulfates, Alkyl ether phosphates and alkyl ether carboxylates can contain from 1 to 10 ethylene oxide or propylene oxide units, preferably 1 to 3 ethylene oxide units in the molecule exhibit.

Suitable are, for example, sodium lauryl sulfate, ammonium lauryl sulfate, sodium lauryl ether sulfate, Ammonium lauryl ether sulfate, sodium lauroyl sarcosinate, sodium oleyl succinate, Ammonium laurylsulfosuccinate, sodium dodecylbenzenesulfonate, triethanolamine dodecylbenzenesulfonate.

suitable amphoteric surfactants are, for example, alkylbetaines, alkylamidopropyl betaines, Alkylsulfobetaines, alkylglycinates, alkylcarboxyglycinates, alkylamphoacetates or propionates, alkyl amphodiacetates or dipropionates.

For example can Cocodimethyl sulphopropyl betaine, lauryl betaine, cocamidopropyl betaine or sodium cocamphopropionate.

When Nonionic surfactants are suitable, for example, the reaction products of aliphatic alcohols or alkylphenols having 6 to 20 C atoms in the alkyl chain, which may be linear or branched, with ethylene oxide and / or propylene oxide. The amount of alkylene oxide is about 6 up to 60 moles per one mole of alcohol. Furthermore, alkylamine oxides, mono- or dialkylalkanolamides, fatty acid esters of polyethylene glycols, alkyl polyglycosides or sorbitan ether esters suitable.

Moreover can the shampoo formulations usual contain cationic surfactants, such as. B. quaternary ammonium compounds, for example Cetyltrimethylammonium chloride.

In the shampoo formulations to achieve certain effects conventional conditioning agents in combination with the microcapsules according to the invention or produced according to the inventive method O / W dispersions can be used.

For this counting for example, the aforementioned cationic polymers with the Designation Polyquaternium according to INCI, in particular copolymers of Vinylpyrrolidone / N-vinylimidazolium salts (Luviquat FC, Luviquat & commat, HM, Luviquat MS, Luviquat Care), copolymers of N-vinylpyrrolidone / dimethylaminoethyl methacrylate, quaternized with diethyl sulfate (Luviquat D PQ 11), copolymers N-vinylcaprolactam / N-vinylpyrrolidone / N vinylimidazolium (Luviquat D Hold), cationic cellulose derivatives (Polyquaternium-4 and -10), acrylamide copolymers (Polyquaternium-7). Furthermore, protein hydrolysates used as well as conditioning substances based on Silicone compounds, for example polyalkylsiloxanes, polyarylsiloxanes, Polyarylalkylsiloxanes, polyethersiloxanes or silicone resins. Further suitable silicone compounds are dimethicone copolyols (CTFA) and amino-functional silicone compounds such as amodimethicone (CTFA). Further can cationic guar derivatives such as guar hydroxypropyltrimonium chloride (INCI) be used.

To a further embodiment serves this hair cosmetic or skin cosmetic preparation of Care or protection of the skin or hair and is in the form of a Emulsion, a dispersion, a suspension, an aqueous Surfactant preparation, a milk, a lotion, a cream, a Balsams, an ointment, a gel, a granule, a powder, a pencil preparation, such as As a lipstick, a foam, an aerosol or of a spray. Such formulations are well suited for topical Preparations. As emulsions come oil-in-water emulsions and Water-in-oil emulsions or microemulsions.

in the As a rule, the dermocosmetic is used to protect the hair for application used on the skin (topically) or hair. Among topical dermocosmetics are to be understood as those dermocemics that are suitable are the active ingredients in fine distribution and preferably in one Apply skin resorbable form to the skin. Suitable for this purpose z. B. aqueous and watery-alcoholic Solutions, sprays, foams, Foam aerosols, ointments, watery Gels, emulsions of O / W or W / O type, microemulsions or cosmetic stick preparations.

To a preferred embodiment of the dermocosmetics according to the invention to protect hair the dermocosmetic a carrier. Preferred as a carrier is water, a gas, a water-based fluid, an oil, a gel, an emulsion or microemulsion, dispersion or mixture from that. The named carriers show a good skin compatibility. Especially advantageous for topical preparations are aqueous Gels, emulsions or microemulsions.

When Emulsifiers can nonionic surfactants, zwitterionic surfactants, ampholytic surfactants or anionic emulsifiers. The emulsifiers can be used in the composition of the invention in amounts of 0.1 to 10, preferably 1 to 5 wt .-%, based on the composition should be included.

As a nonionic surfactant, for example, a surfactant of at least one of the following groups may be used:
Addition products of 2 to 30 moles of ethylene oxide and / or 0 to 5 moles of propylene oxide to linear fatty alcohols having C ₈ -C ₂₂ C atoms, to fatty acids having C ₁₂ -C ₂₂ C atoms and to alkylphenols having C ₈ -C ₁₅ C- Atoms in the alkyl group;
C ₁₂ C ₁₈ fatty acid mono- and diesters of addition products of 1 to 30 moles of ethylene oxide with glycerol; Glycerol mono- and diesters and sorbitan mono- and diesters of saturated and unsaturated fatty acids with C ₆ -C ₂₂ carbon atoms and their ethylene oxide addition products; Alkyl mono- and oligoglycosides having C ₈ -C ₂₂ carbon atoms in the alkyl radical and their ethoxylated analogs; Addition products of 15 to 60 moles of ethylene oxide with castor oil and / or hydrogenated castor oil; Polyol and in particular polyglycerol esters, such as. Polyglycerol polyricinoleate, polyglycerol poly-12-hydroxy stearate or polyglycerol dimerate. Also suitable are mixtures of compounds of several of these classes of substances;
Addition products of 2 to 15 moles of ethylene oxide with castor oil and / or hydrogenated castor oil;
Partial esters based on linear, branched, unsaturated or saturated C _6/22 fatty acids, ricinoleic acid and 12-hydroxystearic acid and glycerol, polyglycerol, pentaerythritol, dipentaerythritol, sugar alcohols (for example sorbitol), alkyl glucosides (for example methyl glucoside , Butylglucoside, lauryl glucoside) as well as polyglucosides (eg cellulose); Mono-, di- and trialkyl phosphates and mono-, di- and / or tri-PEG-alkyl phosphates and their salts;
Lanolin alcohol;
Polysiloxane-polyalkyl-polyether copolymers or corresponding derivatives;
Mixed esters of pentaerythritol, fatty acids, citric acid and fatty alcohol according to DE PS 1165574 and / or mixed esters of fatty acids having C ₆ -C ₂₂ carbon atoms, methyl glucose and polyols, preferably glycerol or polyglycerol and polyalkylene glycols.

Farther can as emulsifiers zwitterionic surfactants are used. As zwitterionic Surfactants become such surface active Compounds referred to in the molecule at least one quaternary ammonium group and at least one carboxylate or sulfonate group. Particularly suitable zwitterionic surfactants are the so-called Betaines such as the N-alkyl-N, N-dimethylammonium glycinates, for example cocoalkyldimethylammonium glycinate, N-acylamino-propyl-N, N dimethylammonium glycinates, for example cocoacylaminopropyldimethylammonium glycinate, and 2-alkyl-3-carboxymethyl-3-hydroxy-ethylimidazolines each 8 to 18 carbon atoms in the alkyl or acyl group and the Kokosacylaminoethylhydroxyethyl-carboxymethylglycinat. This is particularly preferred under the CTFA name Cocamidopropyl Betaine known fatty acid amide derivative.

Also suitable emulsifiers are ampholytic surfactants. Ampholytic surfactants are understood as meaning those surface-active compounds which contain, in addition to a C ₈ -C ₁₈ -alkyl or -acyl group in the molecule, at least one free amino group and at least one -COOH or -SO ₃ H group and are capable of forming internal salts , Examples of suitable ampholytic surfactants are N-alkylglycines, N-alkylpropionic acids, N-alkylamino-butyric acids, N-alkyliminodipropionic acids, N-hydroxyethyl-N-alkylamido-propylglycines, N-alkyltaurines, N-alkylsarcosines, 2-alkylaminopropionic acids and alkylaminoacetic acids each having about 8 to 18 C atoms in the alkyl group.

Particularly preferred ampholytic surfactants are N-cocoalkylaminopropionate, cocoacylaminoethylaminopropionate and C ₁₂ -C ₁₈ acylsarcosine. In addition to the ampholytic, quaternary emulsifiers are also suitable, those of the esterquat type, preferably methyl-quaternized difatty acid triethanolamine ester salts, being particularly preferred. In addition, alkyl ether sulfates, monoglyceride sulfates, fatty acid sulfates, sulfosuccinates and / or ether carboxylic acids can be used as anionic emulsifiers.

Guerbet alcohols based on fatty alcohols containing 6 to 18, preferably 8 to 10, carbon atoms, esters of linear C ₆ -C ₂₂ fatty acids with linear C ₆ -C ₂₂ fatty acids, esters of branched C ₆ -C ₁₃ carboxylic acids are also included as oil bodies linear C ₆ -C ₂₂ -fatty alcohols, esters of linear C ₆ -C ₂₂ -fatty acids with branched alcohols, in particular 2-ethylhexanol, esters of linear and / or branched fatty acids with polyhydric alcohols (such as, for example, propylene glycol, dimerdiol or trimer triol ) and / or Guerbet alcohols, triglycerides based on C ₆ -C ₁₀ fatty acids, liquid mono- / di-, triglyceride mixtures based on C ₆ -C ₁₈ fatty acids, esters of C ₆ -C ₂₂ fatty alcohols and / or Guerbet alcohols with aromatic carboxylic acids, in particular benzoic acid, esters of C ₂ -C ₁₂ dicarboxylic acids with linear or branched alcohols having 1 to 22 carbon atoms or polyols having 2 to 10 carbon atoms and 2 to 6 hydroxyl groups, vegetable oils, verzw eigte primary alcohols, substituted cyclohexanes, linear C ₆ -C ₂₂ fatty alcohol, Guerbetcarbonate, esters of benzoic acid with linear and / or branched C ₆ -C ₂₂ alcohols (eg. B. Finsolv ^® TN), dialkyl ethers, ring-opening products of epoxidized fatty acid esters with polyols, silicone oils and / or aliphatic or naphthenic hydrocarbons into consideration. As oil body can also be used also silicone compounds, for example dimethylpolysiloxanes, Methylphenylpolysiloxane, cyclic silicones and amino, fatty acid, alcohol, polyether, epoxy, fluorine, alkyl and / or glycoside-modified silicone compounds which are both liquid at room temperature may be resinous. The oil bodies may be present in the compositions according to the invention in amounts of from 1 to 90, preferably from 5 to 80, and in particular from 10 to 50,% by weight, based on the composition.

perfumes

A another embodiment dermocosmetics are perfumes, the at least one of the compounds (V), mixtures (M1) or (M2), Preparations, colorants, Vesicles or carotenoid formulations contain or under their Use have been made.

Perfumes are alcoholic solutions suitable fragrances or perfumes, which are mostly made from perfume oils or of synthetic origin but also contain substances can, obtained from animals and, for example, animal glandular secretions are. perfumes be except for use on the human body and often used for the scent design of numerous solids and liquids. Perfumes can in Groups are divided according to the content of perfume oils in particular pure ethanol, optionally with water up to 70% by weight dilute can be correct. As a rule, the following is subdivided into: perfume 10-25% by weight; Eau de Parfum 8-10% Wt .-%; Eau de Toilette 5-8% Wt .-%; Eau de Cologne (cologne Water) 2-5% Wt .-%.

The fragrance effect of a perfume is usually composed of three elements; a top note that contains volatile fragrances or perfume oils with mostly fresh character, a middle note that contains moderately volatile fragrances or perfume oils often flowery character and a base note with low-volatile fragrances or perfume oils and determine the basic character (Leitgeruch) of the perfume , Perfumes can be subdivided into fragrance groups or fragrances or notes: Aldehyde-like fragrances contain C ₆ - to C ₁₂ -aldehydes, which smell fresh and fruity. Green notes consist predominantly of fresh, dry synthetic aldehydes, alcohols and esters. Flowery notes are complex mixtures of jasmine absolues, rose oil, synthetic fragrances such as benzyl acetate, phenylethyl alcohol. Herbaceous notes include, for example, lavender, moss extracts and spices such as cinnamon and are often used in men's perfumes. Oriental notes are heavy and sweet and often enhanced with animal notes.

Of the Basenotes are generally associated with fixators, which bind and adhesive strength of the volatile Increase fragrances and stabilize the fragrance composition. With adjuvants, top notes, Middle note and base note more closely linked and the scent flow flowing be designed. Fixateurs can, for example in self-fixatives, pseudofixators, real fixatives or stimulants and from natural products, synthetic analogues or synthetic substances. They are in liquid or in viscous to crystalline form. Examples of substances or extracts which can act as fixatives are coumarin, diethylene glycol methyl ether, Ambergris, castoreum, musk, civet, muscone, some macrolides, fixator 404 or extracts of labdanum, styrax, tolu balsam, benzoin, iris, Oakmoss, Opopanax.

In the perfumes are additional to the perfume oils or Fragrances or other substances such as emulsifiers or fragrances Stabilizer, antioxidant or preservative.

The perfumes according to the invention usually from 0.01 to 30% by weight, preferably from 0.01% by weight to 15% by weight, particularly preferably 0.05 to 5% by weight, very particularly preferably 0.1 up to 2% by weight of the antioxidants according to the invention, the mixtures (M1) or (M2), the preparation, of the coloring matter, the vesicle or carotenoid formulations, based on the total weight of the perfume.

Perfumes will be Mostly applied topically to human skin, but they can for example, also serve to improve the indoor air or in other dermocosmetics, for example soaps or ointments, pharmaceuticals, Solids or liquids or mixtures thereof are used or combined with these.

Mouth, tooth, and dentures

Further Uses of the antioxidants of the invention, mixtures (M1) or (M2), preparations, colorants, Vesicles or carotenoid formulations are agents for oral, dental and denture care containing or under their own Use have been made

Means for oral, dental and dental care in the context of the present invention means all the oral, dental and dental hygiene appropriate means and supply forms as in textbooks, z. B. Umbach: Cosmetics: Development, production and application of cosmetic means, chapter 7, page 187-219, 2nd extended edition, 1995, Georg Thieme publishing house, ISBN 3 13 712602 9 , which are incorporated herein by reference. These means and forms of offer are familiar to the expert and include z. As toothpowder, toothpastes, toothpastes, children's toothpastes, dental gels, liquid tooth creams, mouth water and mouthwash, but this list is not exhaustive.

The preparation of such agents is familiar to the person skilled in the art and may be general textbooks (e.g. Umbach: Cosmetics: Development, production and application of cosmetic products, 2nd extended edition, 1995, Georg Thieme Verlag, ISBN 3 13 7126029 ).

Thus, in addition to the antioxidants, mixtures (M1) or (M2), preparations, colorants, vesicles or carotenoid formulations according to the invention, these agents may also contain further ingredients known to the person skilled in the art. These may be, for example, surfactants, cleaning agents, binders, humectants, consistency regulators, preservatives, dyes, flavors and sweeteners, although this list is not exhaustive. The active substances and auxiliaries mentioned may be active substances and adjuvants which prevent tooth decay and gingivitis. In particular, the fluoride is to be mentioned. Furthermore, these active ingredients and adjuvants z. B. against plaque bacteria and calculus, promote remineralization, desensitize sensitive tooth necks or protect the gums, this list is not exhaustive. On the in the textbook Umbach: Cosmetics: Development, production and application of cosmetic products, 2nd extended edition, 1995, Georg Thieme Verlag, ISBN 3 13 712602 9, on pages 205 to 207 Illustrated recipe examples are hereby incorporated by reference.

The agents according to the invention for oral, dental and dental care usually contain 0.01 to 30% by weight, preferably 0.01% by weight to 15% by weight, particularly preferably From 0.05 to 5% by weight, very particularly preferably from 0.1 to 2% by weight, of the antioxidants according to the invention, the mixtures (M1) or (M2), the preparation, of the coloring matter, the vesicle or the carotenoid formulations, based on the Total weight of the agent for oral, dental and dental care.

The Application of the means for oral, dental and dental care are the expert and user of these funds usually known. The Means are introduced in sufficient quantity either in the mouth or for example in a suitable vessel with the to be cleaned or to be nursed object, such as the dentures, in contact brought and after a dependent of the respective agent exposure period removed again. For the use of oral, dental and dental restorative products can possibly further aids such as toothbrushes are needed.

pharmaceuticals

A another embodiment The present invention relates to the use of the antioxidants according to the invention, Mixtures (M1) or (M2), preparations, colorants, vesicles or carotenoid formulations in pharmaceutical preparations. The antioxidant protective effect may be the active pharmaceutical ingredient, as well as other ingredients the pharmaceutical composition, for example formulation auxiliaries and stabilize the pharmaceutical concerned Preparation, for example, lead.

pharmaceutical Agents are all agents containing at least one pharmaceutical active substance in a pharmaceutically active concentration and to Prophylaxis or therapy of diseases applied to humans or animals become. You can for example in the form of aerosols, juices, drops, ointments, gels, Tablets, dragees, or suppositories or in other aids, such as patches, be included.

Farther can the antioxidants of the invention also as active substance in pharmaceutical compositions use Find. This plays especially in physiological or pathological processes a role that are affected by oxidations. Examples for such Processes are macular degeneration, inflammatory inflammations, cardiovascular Diseases, atherosclerosis, strokes, heart disease, Alzheimer's and other neurodegenerative processes or hypertension.

in this connection the compounds (V) are preferably in a physiologically acceptable Shape and / or in a watery Milieu more soluble Form before. For example, they are considered physiologically acceptable Salt and derivatized with succinate.

The Pharmaceuticals according to the invention usually contain 0.01 to 30 wt.%, Preferably 0.01 wt.% To 15% by weight, particularly preferably 0.05 to 5% by weight, very particularly preferably 0.1 to 2 wt.% Of the antioxidants of the invention, the mixtures (M1) or (M2), the preparation, the colorant, the vesicle or the carotenoid formulations, based on the total weight of the Pharmaceutical.

The Application of the corresponding pharmaceuticals is directed, for example according to the type, concentration and physiological availability the active substance or active substances contained in the pharmaceuticals. Hangs further they are of the type to be treated or prophylactically treated Illness.

The Application forms, application sites and required drug concentrations are known in the art.

Food and feed

One Another object of the invention is food or feed, the at least one of the compounds (V) or the antioxidants according to the invention, Mixtures (M1) or (M2), preparations, colorants, vesicles or carotenoid formulations or produced using them.

Under Foodstuffs are understood to mean all substances and mixtures, the for are suitable for human consumption. This affects both products such as baked goods, dairy products except cheese, meat products, vegetables and Fruit preparations, dairy products, desserts and sweets, Snacks such as potato chips or pretzel sticks, but also chewing gum, Jelly products or drinks like sodas or alcoholics. These foods can be ready to eat like yogurt, sausages or drinks, as raw products for processing in the domestic Area or in commercial kitchens, as Finished products such as frozen meals or soups or as mixtures for further processing like baking mixes for home use or in bakeries or offered as a pudding powder, for example. Farther The term foods includes a special effect on the body exercise should. Examples of this would be nutraceuticals, functional food, isotonic drinks and dietary supplements in the form of juices, Tablets, effervescent tablets, dragees, gels, jellies, gelatine capsules, Soft gelatin chips, powders or in dispersions, suspensions or solids.

food For the purposes of the invention, foods that are preventive or used therapeutically. Among preventive foods Foods are understood to be beneficial in certain health Ingredients so-called nutraceuticals are enriched or from which noxious Ingredients were removed or reduced. Under therapeutic Foods are foodstuffs for the purposes of this invention understood that both to reduce body weight but also to build muscle z. B. in popular and competitive sports, specifically used in bodybuilding. It is explicit the use according to the invention Antioxidants according to the invention or containing preparations in the dietary foods.

Furthermore, therapeutic agents can bring about an improvement in lean body mass in humans. In one embodiment, therapeutic agents are understood to mean those agents which are used both for the prevention and for the therapeutic treatment of diet-related, genetically induced or metabolic disorders caused by obesity. In the therapeutic treatment of obesity, the compositions of the present invention may be formulated in a manner well known and practiced by those skilled in the art and used in the preparation of pharmaceutical dosage forms using conventional techniques. Deratige techniques are z. In Remington's Pharmaceutical Science Handbook, Mack Publishing Co., New York, USA, 17 Edition 1985 described. Such pharmaceutical dosage forms or food additives may be liquids or solids in the form of, for example, powders, premixes, tablets, capsules, dragees, aerosols, solutions, dispersions or suspensions.

feed are all the compounds necessary for the nutrition of an animal organism be used. Under an animal organism in the sense of the Present invention taxonomically the kingdom of animals Understood (Animalia) associated organisms.

there are the vertebrates (Vertebrata) with the rows of terrestrial vertebrates (Tetrapoda) and fish (Pisces) preferred. Particularly preferred the classes Aves (birds) and mammalia (mammals). Invertebrates, in particular crustaceans such as shrimps and Crayfish or echinoderms such as sea cucumbers (Holothuroidea), however, are not excluded.

All particularly preferred are the families of the true swine (Suidae), Cattle (Bovinae), Pheasant-like (Phasianidae), Duckbill (Anatidae), Horses (Equidae), carp fish (Cyprinidae) and trout fish (Salmonidae).

Out These families are the most preferred, the so-called domestic and farm animals. Among pets within the meaning of the present invention are not free-living, human-adapted animals understood that by humans predominantly be kept in the residential building. Particularly preferred pets are Cats (Fells silvestris forma catus) and dogs (Canis lupus familiaris).

Under Livestock within the meaning of the present invention animals are understood, which are held by humans for economic purposes.

Especially preferred farm animals are the species, domestic cattle (Bos taurus), domestic chicken (Gallus gallus domesticus), domestic pig (Sus scrofa domestica), Domestic sheep (Ovis ammon aries) and domesticated forms of gray goose (Anser anser).

The Compounds (V) or the antioxidants of the invention, mixtures (M1) or (M2), preparations, colorants, Vesicles or carotenoid formulations may be used to protect food and feed against oxidative processes affecting quality and / or used to negatively influence the shelf life of these products become. Here you can they the food or feed in liquid form, for. B. as a dispersion or in solid form z. B. in dried or frozen state be added.

The Food according to the invention or feeds usually contain 0.01 to 30 wt.%, Preferably 0.01 wt.% To 15 wt.%, Particularly preferably 0.05 to 5 wt.%, Whole particularly preferably 0.1 to 2% by weight of the antioxidants according to the invention, the mixtures (M1) or (M2), the preparation, of the coloring matter, the vesicle or the carotenoid formulations, based on the Total weight of the food or feed.

The Application or use of food or feed medium is the Specialist known.

The List of the specified ingredients, which together with the invention or according to the inventive Method of prepared antioxidants according to the invention, mixtures (M1) or (M2), preparations, colorants, Vesicles or carotenoid formulations or according to the inventive method prepared antioxidants, mixtures (M1) or (M2), preparations dye, Vesicles or carotenoid formulations can be used, or for the production of dermocosmetics, pharmaceuticals, food and Feed, solids or liquids or mixtures thereof, is of course not intended to be exhaustive or be considered limiting. The ingredients can be individual or in any combination with each other.

In the following, dermocosmetics according to the invention are described, containing one or more of the compounds (V). These will be briefly referred to as verbs (V) in the examples. It is obvious to the person skilled in the art that all compounds (V) compounds (V) which are referred to as compounds (V) can preferably be used individually but also in any desired combination in the preparations mentioned below. The respectively preferred compound (V) is 3,3'-dihydroxyisoreinieratin. Example 1: Use of VERB. (V) in an emulsion for day care type O / W WS 1%: % Ingredient (INCI) A 1.7 Ceteareth-6, stearyl alcohol 0.7 Ceteareth-25 2.0 Diethylamino hydroxybenzoyl hexyl benzoate 2.0 PEG-14 Dimethicone 3.6 Cetearyl Alcohol 6.0 Ethylhexyl methoxycinnamate 2.0 Dibutyl adipate B 5.0 glycerin 0.2 Disodium EDTA 1.0 panthenol qs preservative 67.8 Aqua the. C 4.0 Caprylic / Capric Triglycerides, Sodium acrylate copolymer D 0.2 Sodium ascorbyl phosphate 1.0 Tocopheryl acetate 0.2 bisabolol 1.0 Caprylic / Capric Triglycerides, Sodium Ascorbate, Tocopherol, Retinol 1.0 oily solution with approx. 5% VERB. (V) e qs Sodium hydroxides WS 5%: % Ingredient (INCI) A 1.7 Ceteareth-6, stearyl alcohol 0.7 Ceteareth-25 2.0 Diethylamino hydroxybenzoyl hexyl benzoate 2.0 PEG-14 Dimethicone 3.6 Cetearyl Alcohol 6.0 Ethylhexyl methoxycinnamate 2.0 Dibutyl adipate B 5.0 glycerin 0.2 Disodium EDTA 1.0 panthenol qs preservative 63.8 Aqua the. C 4.0 Caprylic / Capric Triglyceride, Sodium Acrylate Copolymer D 0.2 Sodium ascorbyl phosphate 1.0 Tocopheryl acetate 0.2 bisabolol 1.0 Caprylic / Capric Triglycerides, Sodium Ascorbate, Tocopherol, Retinol 0.5 oily solution with approx. 5% VERB. (V) e qs Sodium hydroxides

production: Heat phases A and B separately to approx. 80 ° C. phase Stir B into phase A. and homogenize. Stir phase C into the combined phases A and B and Homogenize again. While stirring to about 40 ° C cooling down, Add phase D, adjust the pH to about 6.5 with phase E. and homogenize and stir cool to room temperature.

Note: The formulation is produced without inert gas. The filling must be carried out in oxygen-impermeable packaging, eg aluminum tubes. Example 2: Use of VERB. (V) in a protective day cream type O / W WS 1%: % Ingredient (INCI) A 1.7 Ceteareth-6, stearyl alcohol 0.7 Ceteareth-25 2.0 Diethylamino hydroxybenzoyl hexyl benzoate 2.0 PEG-14 Dimethicone 3.6 Cetearyl Alcohol 6.0 Ethylhexyl methoxycinnamate 2.0 Dibutyl adipate B 5.0 glycerin 0.2 Disodium EDTA 1.0 panthenol qs preservative 68.6 Aqua the. C 4.0 Caprylic / Capric Triglyceride, Sodium Acrylate Copolymer D 1.0 Sodium ascorbyl phosphate 1.0 Tocopheryl acetate 0.2 bisabolol 1.0 oily solution with approx. 5% VERB. (V) e qs Sodium hydroxides WS 5%: % Ingredient (INCI) A 1.7 Ceteareth-6, stearyl alcohol 0.7 Ceteareth-25 2.0 Diethylamino hydroxybenzoyl hexyl benzoate 2.0 PEG-14 Dimethicone 3.6 Cetearyl Alcohol 6.0 Ethylhexyl methoxycinnamate 2.0 Dibutyl adipate B 5.0 glycerin 0.2 Disodium EDTA 1.0 panthenol qs preservative 64.6 Aqua the. C 4.0 Caprylic / Capric Triglyceride, Sodium Acrylate Copolymer D 1.0 Sodium ascorbyl phosphate 1.0 Tocopheryl acetate 0.2 bisabolol 5.0 oily solution with approx. 5% VERB. (V) e qs Sodium hydroxides

Preparation: Heat phases A and B separately from each other to approx. 80 ° C. Stir phase B into phase A and homogenize. Incorporate phase C into the combined phases A and B and homogenize. Cool with stirring to about 40 ° C. Add phase D, adjust the pH to about 6.5 with phase E and homogenize. Cool to room temperature while stirring. Example 3: Use of VERB. (V) in a facial cleansing lotion type O / W WS 1%: % Ingredient (INCI) A 10.0 Cetearyl ethylhexanoate 10.0 Caprylic / Capric Triglycerides 1.5 Cyclopentasiloxanes, cyclohexasilosans 2.0 PEG-40 Hydrogenated Castor Oil B 3.5 Caprylic / Capric Triglyceride, Sodium Acrylate Copolymer C 1.0 Tocopheryl acetate 0.2 bisabolol qs preservative qs perfume oil D 3.0 Polyquaternium-44 0.5 Cocotrimonium methosulfates 0.5 Ceteareth-25 2.0 Panthenol, Propylene Glycol 4.0 Propylene glycol 0.1 Disodium EDTA 1.0 oily solution with approx. 5% VERB. (V) 60.7 Aqua the. WS 5%: % Ingredient (INCI) A 10.0 Cetearyl ethylhexanoate 10.0 Caprylic / Capric Triglycerides 1.5 Cyclopentasiloxanes, cyclohexasilosans 2.0 PEG-40 Hydrogenated Castor Oil B 3.5 Caprylic / Capric Triglyceride, Sodium Acrylate Copolymer C 1.0 Tocopheryl acetate 0.2 bisabolol qs preservative qs perfume oil D 3.0 Polyquaternium-44 0.5 Cocotrimonium methosulfates 0.5 Ceteareth-25 2.0 Panthenol, Propylene Glycol 4.0 Propylene glycol 0.1 Disodium EDTA 5.0 oily solution with approx. 5% VERB. (V) 56.7 Aqua the.

Preparation: Release phase A. Stir phase B into phase A, incorporate phase C into combined phases A and B. Dissolve phase D, stir into the combined phases A, B and C and homogenize. Stir for 15 minutes. Example 4: Use of VERB. (V) in a Daily Care Body Spray WS 1%: % Ingredient (INCI) A 3.0 Ethylhexyl methoxycinnamate 2.0 Diethylamino hydroxybenzoyl hexyl benzoate 1.0 Polyquaternium-44 3.0 Propylene QGlycol 2.0 Panthenol, Propylene Glycol 1.0 Cyclopentasiloxanes, cyclohexasiloxanes 10.0 octyldodecanol 0.5 PVP 10.0 Caprylic / Capric Triglycerides 3.0 C12-15 alkyl benzoates 3.0 glycerin 1.0 Tocopheryl acetate 0.3 bisabolol 1.0 oily solution with approx. 5% VERB. (V) 59.2 Alcohol WS 5%: % Ingredient (INCI) A 3.0 Ethylhexyl methoxycinnamate 2.0 Diethylamino hydroxybenzoyl hexyl benzoate 1.0 Polyquaternium-44 3.0 Propylene glycol 2.0 Panthenol, Propylene Glycol 1.0 Cyclopentasiloxanes, cyclohexasiloxanes 10.0 octyldodecanol 0.5 PVP 10.0 Caprylic / Capric Triglycerides 3.0 C12-15 alkyl benzoates 3.0 glycerin 1.0 Tocopheryl acetate 0.3 bisabolol 5.0 oily solution with approx. 5% VERB. (V) 55.2 Alcohol

Preparation: Weigh in the components of phase A and dissolve clearly. Example 5: Use of VERB. (V) in a skin care gel WS 1%: % Ingredient (INCI) A 3.6 PEG-40 Hydrogenated Castor Oil 15.0 Alcohol 0.1 bisabolol 0.5 Tocopheryl acetate qs perfume oil B 3.0 panthenol 0.6 Carbomer 1.0 oily solution with approx. 5% VERB. (V) 75.4 Aqua, C 0.8 Triethanolamine WS 5%: % Ingredient (INCI) A 3.6 PEG-40 Hydrogenated Castor Oil 15.0 Alcohol 0.1 bisabolol 0.5 Tocopheryl acetate qs perfume oil B 3.0 panthenol 0.6 Carbomer 5.0 oily solution with approx. 5% VERB. (V) 71.4 Aqua, C 0.8 Triethanolamine

Preparation: Clear phase A clearly. Swell phase B and neutralize with phase C. Stir phase A into the homogenized phase B and homogenize. Example 6: Use of VERB. (V) in an aftershave lotion WS 1%: % Ingredient (INCI) A 10.0 Cetearyl ethylhexanoate 5.0 Tocopheryl acetate 1.0 bisabolol 0.1 perfume oil 0.3 Acrylates / C10-30 Alkyl Acrylate Crosspolymer B 15.0 Alcohol 1.0 panthenol 3.0 glycerin 1.0 oily solution with approx. 5% VERB. (V) 0.1 Triethanolamine 63.5 Aqua the. WS 5%: % Ingredient (INCI) A 10.0 Cetearyl ethylhexanoate 5.0 Tocopheryl acetate 1.0 bisabolol 0.1 perfume oil 0.3 Acrylates / C10-30 Alkyl Acrylate Crosspolymer B 15.0 Alcohol 1.0 panthenol 3.0 glycerin 5.0 oily solution with approx. 5% VERB. (V) 0.1 Triethanolamine 59.5 Aqua the.

Preparation: Mix the components of phase A. Dissolve phase B, work in phase A and homogenize. Example 7: Use of the VERB. (V) in an after sun lotion WS 1%: % Ingredient (INCI) A 0.4 Acrylates / C10-30 Alkyl Acrylate Crosspolymer 15.0 Cetearyl ethylhexanoate 0.2 bisabolol 1.0 Tocopheryl acetate qs perfume oil B 1.0 panthenol 15.0 Alcohol 3.0 glycerin 1.0 oily solution with approx. 5% VERB. (V) 63.2 Aqua, C 0.2 Triethanolamine WS 5%: % Ingredient (INCI) A 0.4 Acrylates / C10-30 Alkyl Acrylate Crosspolymer 15.0 Cetearyl ethylhexanoate 0.2 bisabolol 1.0 Tocopheryl acetate qs perfume oil B 1.0 panthenol 15.0 Alcohol 3.0 glycerin 5.0 oily solution with approx. 5% VERB. (V) 59.2 Aqua, C 0.2 Triethanolamine

Preparation: Mix the components of phase A. Stir phase B into phase A while homogenizing. Neutralize with Phase C and homogenize again. Example 8: Use of the VERB. (V) in a sunscreen lotion WS 1%: % Ingredient (INCI) A 4.5 Ethylhexyl methoxycinnamate 2.0 Diethylamino hydroxybenzoyl hexyl benzoate 3.0 Octocrylene 2.5 Di-C12-13 alkyl malate 0.5 Tocopheryl acetate 4.0 Polyglyceryl-3 Methyl Glucose Distearate B 3.5 Cetearyllsononanoate 1.0 VP / eicosene copolymer 5.0 Isohexadecane 2.5 Di-C12-13 alkyl malate 3.0 Titanium dioxides, trimethoxycaprylylsilanes C 5.0 glycerin 1.0 Sodium Cetearyl Sulfate 0.5 Xanthan gum 59.7 Aqua the. D 1.0 oily solution with approx. 5% VERB. (V) 1.0 Phenoxyethanol, methylparaben, ethylparaben, butylparaben, propylparaben, isobutylparaben 0.3 bisabolol WS 5%: % Ingredient (INCI) A 4.5 Ethylhexyl methoxycinnamate 2.0 Diethylamino hydroxybenzoyl hexyl benzoate 3.0 Octocrylene 2.5 Di-C12-13 alkyl malate 0.5 Tocopheryl acetate 4.0 Polyglyceryl-3 Methyl Glucose Distearate B 3.5 Cetearyl Isononanoate 1.0 VP / eicosene copolymer 5.0 Isohexadecane 2.5 Di-C12-13 alkyl malate 3.0 Titanium dioxides, trimethoxycaprylylsilanes C 5.0 glycerin 1.0 Sodium Cetearyl Sulfate 0.5 Xanthan gum 55.7 Aqua the. D 5.0 oily solution with approx. 5% VERB. (V) 1.0 Phenoxyethanol, methylparaben, ethylparaben, butylparaben, propylparaben, isobutylparaben 0.3 bisabolol

production: The components of phases A and B separated from each other to ca. Heat to 80 ° C. phase Stir B into phase A. and homogenize. Heat phase C to approx. 80 ° C and homogenize stir into the combined phases A and B.

Cool with stirring to about 40 ° C, add phase D and homogenize again. Example 9: Use of VERB. (V) in a sunscreen lotion type O / W WS 1%: % Ingredient (INCI) A 2.0 Ceteareth-6, stearyl alcohol 2.0 Ceteareth-25 3.0 Tribehenin 2.0 Cetearyl Alcohol 2.0 Cetearyl ethylhexanoate 5.0 Ethylhexyl methoxycinnamate 1.0 Ethylhexyl triazone 1.0 VP / eicosene copolymer 7.0 Isopropyl myristate B 5.0 Zinc oxides, triethoxycaprylylsilanes C 0.2 Xanthan gum 0.5 Hydroxyethyl Acrylates / Sodium Acryloyl Dimethyl Taurate Copolymer, Squalane, polysorbate 60 0.2 Disodium EDTA 5.0 Propylene glycol 0.5 panthenol 60.9 Aqua the. D 1.0 oily solution with approx. 5% VERB. (V) 0.5 Phenoxyethanol, methylparaben, butylparaben, ethylparaben, propylparaben, isopropylparaben 1.0 Tocopheryl acetate 0.2 bisabolol WS 5%: % Ingredient (INCI) A 2.0 Ceteareth-6, stearyl alcohol 2.0 Ceteareth-25 3.0 Tribehenin 2.0 Cetearyl Alcohol 2.0 Cetearyl ethylhexanoate 5.0 Ethylhexyl methoxycinnamate 1.0 Ethylhexyl triazone 1.0 VP / eicosene copolymer 7.0 Isopropyl myristate B 5.0 Zinc oxides, triethoxycaprylylsilanes C 0.2 Xanthan gum 0.5 Hydroxyethyl Acrylates / Sodium Acryloyl Dimethyl Taurate Copolymer, Squalane, polysorbate 60 0.2 Disodium EDTA 5.0 Propylene glycol 0.5 panthenol 56.9 Aqua the. D 5.0 oily solution with approx. 5% VERB. (V) 0.5 Phenoxyethanol, methylparaben, butylparaben, ethylparaben, propylparaben, isopropylparaben 1.0 Tocopheryl acetate 0.2 bisabolol

Preparation: Heat phase A to approx. 80 ° C., stir in phase B and homogenize for 3 minutes. Heat Phase C also to 80 ° C and stir with homogenization in the combined phases A and B. Cool to about 40 ° C, stir in phase D and homogenize again. Example 10: Use of VERB. (V) in a sunscreen lotion type O / W WS 1%: % Ingredient (INCI) A 3.5 Ceteareth-6, stearyl alcohol 1.5 Ceteareth-25 7.5 Ethylhexyl methoxycinnamate 2.0 Diethylamino hydroxybenzoyl hexyl benzoate 2.0 Cyclopentasiloxanes, cyclohexasiloxanes 0.5 Bees Wax 3.0 Cetearyl Alcohol 10.0 Caprylic / Capric Triglycerides B 5.0 Titanium Dioxide, Silica, Methicone, Alumina C 3.0 glycerin 0.2 Disodium EDTA 0.3 Xanthan gum 1.0 Decyl glucosides 2.0 Panthenol, Propylene Glycol 56.3 Aqua the. D 1.0 oily solution with approx. 5% VERB. (V) 1.0 Tocopheryl acetate 0.2 bisabolol qs perfume oil qs preservative WS 5%: % Ingredient (INCI) A 3.5 Ceteareth-6, stearyl alcohol 1.5 Ceteareth-25 7.5 Ethylhexyl methoxycinnamate 2.0 Diethylamino hydroxybenzoyl hexyl benzoate 2.0 Cyclopentasiloxanes, cyclohexasiloxanes 0.5 Bees Wax 3.0 Cetearyl Alcohol 10.0 Caprylic / Capric Triglycerides B 5.0 Titanium Dioxide, Silica, Methicone, Alumina C 3.0 glycerin 0.2 Disodium EDTA 0.3 Xanthan gum 1.0 Decyl glucosides 2.0 Panthenol, Propylene Glycol 52.3 Aqua the. D 5.0 oily solution with approx. 5% VERB. (V) 1.0 Tocopheryl acetate 0.2 bisabolol qs perfume oil qs preservative

Preparation: Heat phase A to approx. 80 ° C., stir in phase B and homogenize for 3 minutes. Phase C also warm to 80 ° C and stir with homogenization in the combined phases A and B. Cool to about 40 ° C, stir in phase D and homogenize again. Example 11: Use of VERB. (V) in a foot balm WS 1%: % Ingredient (INCI) A 2.0 Ceteareth-6, stearyl alcohol 2.0 Ceteareth-25 5.0 Cetearyl ethylhexanoate 4.0 Cetyl Alcohol 4.0 Glyceryl stearate 5.0 Mineral oil 0.2 menthol 0.5 Camphor B 69.3 Aqua the. qs preservative C 1.0 bisabolol 1.0 Tocopheryl acetate D 1.0 oily solution with approx. 5% VERB. (V) 5.0 Witch Hazel Extract WS 5%: % Ingredient (INCI) A 2.0 Ceteareth-6, stearyl alcohol 2.0 Ceteareth-25 5.0 Cetearyl ethylhexanoate 4.0 Cetyl Alcohol 4.0 Glyceryl stearate 5.0 Mineral oil 0.2 menthol 0.5 Camphor B 65.3 Aqua the. qs preservative C 1.0 bisabolol 1.0 Tocopheryl acetate D 5.0 oily solution with approx. 5% verb. (V) 5.0 Witch Hazel Extract

Preparation: Heat the components of phases A and B separately from each other to approx. 80 ° C. Stir phase B into phase A while homogenizing. Cool with stirring to about 40 ° C, add the phases C and D and briefly nachhomogenisieren. Cool to room temperature while stirring. Example 12: Use of VERB. (V) in a W / O emulsion with bisabolol WS 1%: % Ingredient (INCI) A 6.0 PEG-7 Hydrogenated Castor Oil 8.0 Cetearyl ethylhexanoate 5.0 Isopropyl myristate 15.0 Mineral oil 0.3 Magnesium Stearate 0.3 Aluminum stearate 2.0 PEG-45 / dodecyl glycol copolymer B 5.0 glycerin 0.7 Magnesium sulphates 55.6 Aqua the. C 1.0 oily solution with approx. 5% VERB. (V) 0.5 Tocopheryl acetate 0.6 bisabolol WS 5%: % Ingredient (INCI) A 6.0 PEG-7 Hydrogenated Castor Oil 8.0 Cetearyl ethylhexanoate 5.0 Isopropyl myristate 15.0 Mineral oil 0.3 Magnesium Stearate 0.3 Aluminum stearate 2.0 PEG-45 / dodecyl glycol copolymer B 5.0 glycerin 0.7 Magnesium sulphates 51.6 Aqua the. C 5.0 oily solution with approx. 5% VERB. (V) 0.5 Tocopheryl acetate

production: Heat phases A and B separately to about 85 ° C. phase Stir B into phase A. and homogenize. While stirring to about 40 ° C cooling down, Add phase C and homogenize briefly again. While stirring Cool room temperature.

Compilation formulas for patent Keratin-binding domain-Hair Care

Example 13: Foam Conditioner with Fixer WS 1% % Ingredient (INCI) A 10.0 PVPNA copolymer 0.2 Hydroxyethyl cetyldimonium phosphates 0.2 Ceteareth-25 0.5 Dimethicone Copolyol qs perfume oil 10.0 Alcohol 1.0 oily solution with approx. 5% VERB. (V) 68.1 Aqua the. 10.0 Propane / Butane WS 5% % Ingredient (INCI) A 10.0 PVPNA copolymer 0.2 Hydroxyethyl cetyldimonium phosphates 0.2 Ceteareth-25 0.5 Dimethicone Copolyol qs perfume oil 10.0 Alcohol 5.0 oily solution with approx. 5% VERB. (V) 64.1 Aqua the. 10.0 Propane / Butane

Preparation: Weigh the components of phase A together, stir until everything is dissolved and bottled. Example 14: Foam conditioner WS 1% % Ingredient (INCI) A 1.0 Polyquaternium-4 0.5 Hydroxyethyl cetyldimonium phosphates 1.0 oily solution with approx. 5% VERB. (V) qs perfume oil qs preservative 91.5 Aqua the. 6.0 Propane / Butane WS 5% % Ingredient (INCI) A 1.0 Polyquaternium-4 0.5 Hydroxyethyl cetyldimonium phosphates 5.0 oily solution with approx. 5% VERB. (V) qs perfume oil qs preservative 87.5 Aqua the. 6.0 Propane / Butane

Production: Weigh the components of phase A together, stir until everything is clearly dissolved and bottled. Example 15: Foam conditioner WS 1% % Ingredient (INCI) A 1.0 Polyquaternium-11 0.5 Hydroxyethyl cetyldimonium phosphates 1.0 oily solution with approx. 5% VERB. (V) qs perfume oil qs preservative 91.5 Aqua the. 6.0 Propane / Butane WS 5% % Ingredient (INCI) A 1.0 Polyquaternium-11 0.5 Hydroxyethyl cetyldimonium phosphates 5.0 oily solution with approx. 5% VERB. (V) qs perfume oil qs preservative 87.5 Aqua the. 6.0 Propane / Butane

Production: Weigh the components of phase A together, stir until everything is clearly dissolved and bottled. Example 16: Styling foam WS 1% % Ingredient (INCI) A 0.5 Laureth-4 qs perfume oil B 77.3 Aqua the. 10.0 Polyquaternium-28 1.0 oily solution with approx. 5% VERB. (V) 0.5 Dimethicone Copolyol 0.2 Ceteareth-25 0.2 panthenol 0.1 PEG-25 PABA 0.2 hydroxyethyl C 10.0 HFC 152A WS 5% % Ingredient (INCI) A 0.5 Laureth-4 qs perfume oil B 73.3 Aqua the. 10.0 Polyquaternium-28 5.0 oily solution with approx. 5% VERB. (V) 0.5 Dimethicone Copolyol 0.2 Ceteareth-25 0.2 panthenol 0.1 PEG-25 PABA 0.2 hydroxyethyl C 10.0 HFC 152A

Preparation: Mix the components of phase A. Add the components of phase B one by one and dissolve. Fill with phase C. Example 17: Styling foam WS 1% % Ingredient (INCI) A 2.0 Cocotrimonium methosulfates qs perfume oil B 78.5 Aqua the. 6.7 Acrylates copolymer 0.6 AMP 1.0 oily solution with approx. 5% VERB. (V) 0.5 Dimethicone Copolyol 0.2 Ceteareth-25 0.2 panthenol 0.1 PEG-25 PABA 0.2 hydroxyethyl C 10.0 HFC 152A WS 5% % Ingredient (INCI) A 2.0 Cocotrimonium methosulfates qs perfume oil B 74.5 Aqua the. 6.7 Acrylates copolymer 0.6 AMP 5.0 oily solution with approx. 5% VERB. (V) 0.5 Dimethicone Copolyol 0.2 Ceteareth-25 0.2 panthenol 0.1 PEG-25 PABA 0.2 hydroxyethyl C 10.0 HFC 152A

Preparation: Mix the components of phase A. Add the components of phase B one by one and dissolve. Fill with phase C. Example 18: Styling foam WS 1% % Ingredient (INCI) A 2.0 Cocotrimonium methosulfates qs perfume oil B 7.70 Polyquaternium-44 1.0 oily solution with approx. 5% VERB. (V) qs preservative 79.3 Aqua the. C 10.0 Propane / Butane WS 5% % Ingredient (INCI) A 2.0 Cocotrimonium methosulfates qs perfume oil B 7.70 Polyquaternium-44 5.0 oily solution with approx. 5% VERB. (V) qs preservative 75.3 Aqua the. C 10.0 Propane / Butane

Preparation: Mix the components of phase A. Clear the components of phase B, then stir phase B into phase A. Adjust the pH to 6-7, fill with phase C. Example 19: Styling foam WS 1% % Ingredient (INCI) A 2.00 Cocotrimonium methosulfates qs perfume oil B 72.32 Aqua the. 2.00 VP / Acrylates / Lauryl Methacrylate Copolymer 0.53 AMP 1.00 oily solution with approx. 5% VERB. (V) 0.20 Ceteareth-25 0.50 panthenol 0.05 Benzophenone-4 0.20 Amodimethicone, Cetrimonium Chloride, Trideceth-12 15.00 Alcohol C 0.20 hydroxyethyl D 6.00 Propane / Butane WS 5% % Ingredient (INCI) A 2.00 Cocotrimonium methosulfates qs perfume oil B 68.32 Aqua the. 2.00 VP / Acrylates / Lauryl Methacrylate Copolymer 0.53 AMP 5.00 oily solution with approx. 5% VERB. (V) 0.20 Ceteareth-25 0.50 panthenol 0.05 Benzophenone-4 0.20 Amodimethicone, Cetrimonium Chloride, Trideceth-12 15.00 Alcohol C 0.20 hydroxyethyl D 6.00 Propane / Butane

Preparation: Mix the components of phase A. Add the components of phase B one by one and dissolve. Dissolve phase C in the mixture of A and B, then adjust the pH to 6-7. Fill with phase D. Example 20: Styling foam WS 1% % Ingredient (INCI) A 2.00 Cetrimonium chlorides qs perfume oil B 67.85 Aqua the. 7.00 Polyquaternium-46 1.00 oily solution with approx. 5% VERB. (V) 0.20 Ceteareth-25 0.50 panthenol 0.05 Benzophenone-4 0.20 Amodimethicone, Cetrimonium Chloride, Trideceth-12 15.00 Alcohol C 0.20 hydroxyethyl D 6.00 Propane / Butane WS 5% % Ingredient (INCI) A 2.00 Cetrimonium chlorides qs perfume oil B 63.85 Aqua the. 7.00 Polyquaternium-46 5.00 oily solution with approx. 5% VERB. (V) 0.20 Ceteareth-25 0.50 panthenol 0.05 Benzophenone-4 0.20 Amodimethicone, Cetrimonium Chloride, Trideceqth-12 15.00 Alcohol C 0.20 hydroxyethyl D 6.00 Propane / Butane

Preparation: Mix the components of phase A. Add the components of phase B one by one and dissolve. Dissolve phase C in the mixture of A and B, then adjust the pH to 6-7. Fill with phase D. Example 26: Styling foam WS 1% % Ingredient (INCI) A qs PEG-40 Hydrogenated Castor Oil qs perfume oil 85.5 Aqua the. B 7.0 Sodium Polystyrene Sulfonate 1.0 oily solution with approx. 5% VERB. (V) 0.5 Cetrimonium bromides qs preservative C 6.0 Propane / Butane Styling foam WS 5% % Ingredient (INCI) A qs PEG-40 Hydrogenated Castor Oil qs perfume oil 81.5 Aqua the. B 7.0 Sodium Polystyrene Sulfonate 5.0 oily solution with approx. 5% VERB. (V) 0.5 Cetrimonium bromides qs preservative C 6.0 Propane / Butane

Preparation: Solubilize phase A. Weigh phase B into phase A and solve it clearly. Adjust the pH to 6-7, fill with phase C. Example 27: Styling Foam WS 1% % Ingredient (INCI) A qs PEG-40 Hydrogenated Castor Oil qs perfume oil 92.0 Aqua the. B 0.5 Polyquaternium-10 1.0 oily solution with approx. 5% VERB. (V) 0.5 Cetrimonium bromides qs preservative C 6.0 Propane / Butane WS 5% % Ingredient (INCI) A qs PEG-40 Hydrogenated Castor Oil qs perfume oil 88.0 Aqua the. B 0.5 Polyquaternium-10 5.0 oily solution with approx. 5% VERB. (V) 0.5 Cetrimonium bromides qs preservative C 6.0 Propane / Butane

Preparation: Solubilize phase A. Weigh phase B into phase A and solve it clearly. Adjust the pH to 6-7, fill with phase C. Example 28: Styling foam WS 1% % Ingredient (INCI) A qs PEG-40 Hydrogenated Castor Oil qs perfume oil 82.5 Aqua the. B 10.0 Polyquaternium-16 1.0 oily solution with approx. 5% VERB. (V) 0.5 Hydroxyethyl cetyldimonium phosphates qs preservative C 6.0 Propane / Butane WS 5% % Ingredient (INCI) A qs PEG-40 Hydrogenated Castor Oil qs perfume oil 78.5 Aqua the. B 10.0 Polyquaternium-16 5.0 oily solution with approx. 5% VERB. (V) 0.5 Hydroxyethyl cetyldimonium phosphates qs preservative C 6.0 Propane / Butane

Preparation: Solubilize phase A. Weigh phase B into phase A and clear. Adjust the pH to 6-7, fill with phase C. Example 29: Styling foam WS 1% % Ingredient (INCI) A 2.0 Cocotrimonium methosulfates qs perfume oil B 84.0 Aqua the. 2.0 chitosan 1.0 oily solution with approx. 5% VERB. (V) 0.5 Dimethicone Copolyol 0.2 Ceteareth-25 0.2 panthenol 0.1 PEG-25 PABA C 10.0 HFC 152A WS 5% % Ingredient (INCI) A 2.0 Cocotrimonium methosulfates qs perfume oil B 80.0 Aqua the. 2.0 chitosan 5.0 oily solution with approx. 5% VERB. (V) 0.5 Dimethicone Copolyol 0.2 Ceteareth-25 0.2 panthenol 0.1 PEG-25 PABA C 10.0 HFC 152A

Preparation: Mix the components of phase A. Add the components of phase B one by one and dissolve. Fill with phase C. Example 30: care shampoo WS 1% % Ingredient (INCI) A 30.0 Sodium Laureth Sulfate 6.0 Sodium cocoamphoacetate 6.0 Cocamidopropyl betaines 3.0 Sodium Laureth Sulfate, Glycol Distearate, Cocamide MEA, Laureth-10 1.0 oily solution with approx. 5% VERB. (V) 7.7 Polyquaternium-44 2.0 amodimethicone qs perfume oil qs preservative 1.0 Sodium Chloride 43.3 Aqua the. B qs Citric Acid WS 5% % Ingredient (INCI) A 30.0 Sodium Laureth Sulfate 6.0 Sodium cocoamphoacetate 6.0 Cocamidopropyl betaines 3.0 Sodium Laureth Sulfate, Glycol Distearate, Cocamide MEA, Laureth-10 5.0 oily solution with approx. 5% VERB. (V) 7.7 Polyquaternium-44 2.0 amodimethicone qs perfume oil qs preservative 1.0 Sodium Chloride 39.3 Aqua the. B qs Citric Acid

Preparation: Mix and dissolve the components of phase A. Adjust the pH to 6-7 with citric acid. Example 31: shower gel WS 1% % Ingredient (INCI) A 40.0 Sodium Laureth Sulfate 5.0 Decyl glucosides 5.0 Cocamidopropyl betaines 1.0 oily solution with approx. 5% VERB. (V) 1.0 panthenol qs perfume oil qs preservative 2.0 Sodium Chloride 46.0 Aqua the. B qs Citric Acid WS 5% % Ingredient (INCI) A 40.0 Sodium Laureth Sulfate 5.0 Decyl glucosides 5.0 Cocamidopropyl betaines 5.0 oily solution with approx. 5% VERB. (V) 1.0 panthenol qs perfume oil qs preservative 2.0 Sodium Chloride 42.0 Aqua the. B qs Citric Acid

Preparation: Mix and dissolve the components of phase A. Adjust the pH to 6-7 with citric acid. Example 32: Shampoo WS 1% % Ingredient (INCI) A 40.0 Sodium Laureth Sulfate 5.0 Sodium C12-15 Pareth-15 sulfonates 5.0 Decyl glucosides qs perfume oil 0.1 phytantriol 44.6 Aqua the. 1.0 oily solution with approx. 5% VERB. (V) 0.3 Polyquaternium-10 1.0 panthenol qs preservative 1.0 Laureth-3 2.0 Sodium Chloride WS 5% % Ingredient (INCI) A 40.0 Sodium Laureth Sulfate 5.0 Sodium C12-15 Pareth-15 sulfonates 5.0 Decyl glucosides qs perfume oil 0.1 phytantriol 40.6 Aqua the. 5.0 oily solution with approx. 5% VERB. (V) 0.3 Polyquaternium-10 1.0 panthenol qs preservative 1.0 Laureth-3 2.0 Sodium Chloride

Preparation: Mix and dissolve the components of phase A. Adjust the pH to 6-7 with citric acid. Example 33: Shampoo WS 1% % Ingredient (INCI) A 15.00 Cocamidopropyl betaines 10.00 Disodium Cocoamphodiacetate 5.00 Polysorbate 20 5.00 Decyl glucosides qs perfume oil qs preservative 1.00 oily solution with approx. 5% VERB. (V) 0.15 Guar hydroxypropyltrimonium chlorides 2.00 Laureth-3 58,00 Aqua the. qs Citric Acid B 3.00 PEG-150 distearate WS 5% % Ingredient (INCI) A 15.00 Cocamidopropyl betaines 10.00 Disodium Cocoamphodiacetate 5.00 Polysorbate 20 5.00 Decyl glucosides qs perfume oil qs preservative 5.00 oily solution with approx. 5% VERB. (V) 0.15 Guar hydroxypropyltrimonium chlorides 2.00 Laureth-3 54,00 Aqua the. qs Citric Acid B 3.00 PEG-150 distearate

Production: Weigh in the components of phase A and dissolve. Adjust the pH to 6-7. Add phase B and warm to approx. 50 ° C. Cool to room temperature while stirring. Example 34: Moisturizing Body Care Cream WS 1% % Ingredient (INCI) A 2.0 Ceteareth-25 2.0 Ceteareth-6, stearyl alcohol 3.0 Cetearyl ethylhexanoate 1.0 Dimethicone 4.0 Cetearyl Alcohol 3.0 Glyceryl Stearate SE 5.0 Mineral oil 4.0 Simmondsia chinensis (Jojoba) Seed Oil 3.0 Mineral Oil, Lanolin Alcohol B 5.0 Propylene glycol 1.0 oily solution with approx. 5% VERB. (V) 1.0 panthenol 0.5 Magnesium Aluminum Silicate qs preservative 65.5 Aqua the. C qs perfume oil D qs Citric Acid WS 5% % Ingredient (INCI) A 2.0 Ceteareth-25 2.0 Ceteareth-6, stearyl alcohol 3.0 Cetearyl ethylhexanoate 1.0 Dimethicone 4.0 Cetearyl Alcohol 3.0 Glyceryl Stearate SE 5.0 Mineral oil 4.0 Simmondsia chinensis (Jojoba) Seed Oil 3.0 Mineral Oil, Lanolin Alcohol B 5.0 Propylene glycol 5.0 oily solution with approx. 5% VERB. (V) 1.0 panthenol 0.5 Magnesium Aluminum Silicate qs preservative 61.5 Aqua the. C qs perfume oil D qs Citric Acid

Preparation: Heat phases A and B separately to approx. 80 ° C. Prehomogenise phase B briefly, then stir phase B into phase A and homogenize again. Cool to about 40 ° C, add phase C and homogenize again well. Adjust the pH to 6-7 with citric acid. Example 35: Moisturizing Body Care Cream WS 1% % Ingredient (INCI) A 6.0 PEG-7 Hydrogenated Castor Oil 10.0 Cetearyl ethylhexanoate 5.0 Isopropyl myristate 7.0 Mineral oil 0.5 Shea Butter (Butyrospermum Parkii) 0.5 Aluminum stearate 0.5 Magnesium Stearate 0.2 bisabolol 0.7 Quaternium-18 hectorites B 5.0 Dipropylene glycol 0.7 Magnesium sulphates qs preservative 62.9 Aqua the. C qs perfume oil 1.0 oily solution with approx. 5% VERB. (V) WS 5% % Ingredient (INCI) A 6.0 PEG-7 Hydrogenated Castor Oil 10.0 Cetearyl ethylhexanoate 5.0 Isopropyl myristate 7.0 Mineral oil 0.5 Shea Butter (Butyrospermum Parkii) 0.5 Aluminum stearate 0.5 Magnesium Stearate 0.2 bisabolol 0.7 Quaternium-18 hectorites B 5.0 Dipropylene glycol 0.7 Magnesium sulphates qs preservative 58.9 Aqua the. C qs perfume oil 5.0 oily solution with approx. 5% VERB. (V)

Preparation: Heat phases A and B separately to approx. 80 ° C. Stir phase B into phase A and homogenize. Cool with stirring to about 40 ° C, add phase C and homogenize again. Allow to cool to room temperature while stirring. Example 36: Liquid make-up type O / W WS 1% % Ingredient (INCI) A A 2.0 Ceteareth-6, stearyl alcohol 2.0 Ceteareth-25 6.0 Glyceryl stearate 1.0 Cetyl Alcohol 8.0 Mineral oil 7.0 Cetearyl ethylhexanoate 0.2 Dimethicone B 3.0 Propylene glycol 1.0 panthenol qs preservative 61.9 Aqua the. C 0.1 bisabolol 1.0 oily solution with approx. 5% VERB. (V) qs perfume oil D 5.7 CI 77 891, Titanium Dioxide 1.1 Iron oxides WS 5% % Ingredient (INCI) A 2.0 Ceteareth-6, stearyl alcohol 2.0 Ceteareth-25 6.0 Glyceryl stearate 1.0 Cetyl Alcohol 8.0 Mineral oil 7.0 Cetearyl ethylhexanoate 0.2 Dimethicone B 3.0 Propylene glycol 1.0 panthenol qs preservative 57.9 Aqua the. C 0.1 bisabolol 5.0 oily solution with approx. 5% VERB. (V) qs perfume oil D 5.7 CI 77 891, Titanium Dioxide 1.1 Iron oxides

production: Heat phases A and B separately to approx. 80 ° C. Stir phase B into phase A and homogenize. While stirring to about 40 ° C cooling down, Add phases C and D and homogenize thoroughly again. Under stir cool to room temperature to let.

Example 37:

in the The following are dermocosmetics according to the invention described, containing the according to Example 1 manufactured VERB. (V). Said VERB. (V) will be in the following Examples as VERB. (V). The verb. (V) will be in the following Examples representative of all others described VERB. (V) used. It is for the expert Of course, that all other active ingredients mentioned prepared according to Example 1 and can be used in the preparations mentioned below.

The named VERB. (V) is used as a solid. The following Details are parts by weight. Clear shampoo Ingredients (INCI) 1 2 3 4 5 Sodium Laureth Sulfate 13,00 15.00 10.50 12.50 10.00 Codamidopropyl betaines 7.50 7.00 5.00 5.50 10.00 PEG-7 glyceryl cocoate 2.00 2.50 3.50 5.00 2.30 perfume oil 0.10 0.10 0.10 0.10 0.10 VERB. (V) 1.0 5.0 0.1 0.5 10.0 D-panthenol USP 1.00 1.50 1.80 1.70 1.40 preservative 0.10 0.10 0.10 0.10 0.10 Citric Acid 0.10 0.10 0.10 0.10 0.10 Luviquat ^® Ultra Care 1.50 1.00 1.50 1.20 1.10 Sodium Chloride 1.50 1.40 1.40 1.30 1.50 Aqua the. ad 100 ad 100 ad 100 ad 100 ad 100   Clear shampoo Ingredients (INCI) 1 2 3 4 5 Sodium Laureth Sulfate 35,00 40,00 30.00 45,00 27.00 Decyl glucosides 5.00 5.50 4.90 3.50 7.00 Cocamidopropyl betaines 10.00 5.00 12.50 7.50 15.00 perfume oil 0.10 0.10 0.10 0.10 0.10 VERB. (V) 1.0 5.0 0.1 0.5 10.0 D-panthenol USP 0.50 1.00 0.80 1.50 0.50 preservative 0.10 0.10 0.10 0.10 0.10 Citric Acid 0.10 0.10 0.10 0.10 0.10 Laureth-3 0.50 2.00 0.50 0.50 2.00 Sodium Chloride 1.50 1.50 1.50 1.50 1.50 Aqua the. ad 100 ad 100 ad 100 ad 100 ad 100    Clear conditioner shampoo Ingredients (INCI) 1 2 3 4 5 ^® Disodium Cocoamphodiacetate 10.00 15.00 20.00 12,00 17.00 ^® Decyl Glucosides 5.00 6.00 7.00 8.00 4.00 ^® Cocamidopropyl Betaine 15.00 12,00 10.00 18,00 20.00 Luviquat.RTM ^® FC 550 0.30 0.20 0.20 0.20 0.30 perfume oil 0.10 0.10 0.10 0.10 0.10 VERB. (V) 20.0 5.0 1.0 0.5 10.0 Cremophor ^® PS 20 5.00 1.00 1.00 7.00 5.00 preservative agent e 0.10 0.10 0.10 0.10 0.10 ^® Laureth-3 2.00 1.00 0.50 2.00 2.00 Citric Acid 0.20 0.20 0.20 0.20 0.20 PEG-12 distearate 3.00 2.00 2.00 3.00 2.50 Aqua the. ad 100 ad 100 ad 100 ad 100 ad 100   Foam O / W emulsions Emulsion 1 Emulsion 2 Wt .-% vol% Wt .-% vol% Stearic acid 5.00 1.00 Cetyl Alcohol 5.50 Cetearyl Alcohol 2.00 PEG-40 Stearates 8.50 PEG-20 stearates 1.00 Caprylic / Capric Triglycerides 4.00 2.00 C12-15 alkyl benzoates 10.00 15.00 Cyclomethicone 4.00 Dimethicone 0.50 VERB. (V) 5.0 10.0 Ethylhexyl isostearates 5.00 Myristyl myristate 2.00 ceresin 1.50 glycerin 3.00 Hydroxypropyl Starch Phosphate 1.00 3.50   BHT 0.02 Disodium EDTA 0.50 0.10 Perfume oil, preservative qs qs colorants qs qs Potassium hydroxides qs qs Aqua the. ad 100 ad 100 Adjust pH to 6.5-7.5 Adjust pH to 5.0-6.0 Emulsion 1 70 Emulsion 2 35 nitrogen 30 Propane / butane 65   Conditioner Shampoo with pearlescent 1 2 3 Polyquaternium-10 0.50 0.50 0.40 Sodium Laureth Sulfate 9.00 8.50 8.90 Codamidopropyl betaines 2.50 2.60 3.00 Uvinul ^® MS 40 1.50 0.50 1.00 VERB. (V) 1.0 5.0 0.5 Perlglanzlösung 2.00 2.50 Disodium EDTA 0.10 0.15 0.05 Preservative, perfume oil, thickener qs qs qs Aqua the. ad 100 ad 100 ad 100  Adjust pH to 6.0 Clear Shamoo Conditioner 1 2 3 Polyquaternium-10 0.50 0.50 0.50 Sodium Laureth Sulfate 9.00 8.50 9.50 VERB. (V) 5.0 0.1 3.0 Uvinul M ^® 40 1.00 1.50 0.50 Preservative, perfume oil, thickener qs qs qs Aqua the. ad 100 ad 100 ad 100  Adjust pH to 6.0 Clear Conditioner Shampoo with Volume effect 1 2 3 Sodium Laureth Sulfate 10.00 10.50 11.00 Uvinul ^® MC 80 2.00 1.50 2.30 VERB. (V) 10.0 0.1 0.5 Cocamidopropyl betaines 2.50 2.60 2.20 Disodium EDTA 0.01 0.10 0.01 Preservative, perfume oil, thickener qs qs qs Aqua the. ad 100 ad 100 ad 100 Adjust pH to 6.0 Gel Cream 1 2 3 4 Acrylates / C10-30 alkyl acrylate crosspolymer 0.40 0.35 0.40 0.35 Carbomer? 0.20 0.22 0.20 0.22 Xanthan gum 0.10 0.13 0.10 0.13 Cetearyl Alcohol 3.00 2.50 3.00 2.50 C12-15 alkyl benzoates 4.00 4.50 4.00 4.50 Caprylic / Capric Triglycerides 3.00 3.50 3.00 3.50 Uvinul ^® A Plus ^TM 2.00 1.50 0.75 1.00 Uvasorb® ^® k2A ethylhexyl bis-Isopentylbenzoxazolylphenyl Melamine 3.00 Uvinul ^® MC 80 3.00 1.00 Bis-Ethylhexyloxyphenol Methoxyphenyl Triazines 1.50 2.00 Butyl methoxydibenzoylmethane 2.00 Disodium phenyl dibenzimidazole tetrasulfonates 2.50 0.50 2.00 Uvinul ^® T 150 4.00 3.00 4.00 Octocrylene 4.00 Diethylhexyl butamido triazone 1.00 2.00 Phenylbenzimidazole sulfonic acid 0.50 3.00 Methylene bis-benzotriazolyl tetramethylbutylphenol 2.00 0.50 1.50 Ethyl hexyl salicylates 3.00 Drometrizole trisiloxanes 0.50 Terephthalid Dicamphor Sulfonic Acid 1.50 1.00 Diethylhexyl 2,6-naphthalate 3.50 4.00 7.00 9.00 Titanium Dioxide microfine 1.00 3.00 Zinc oxide microfine 0.25   VERB. (V) 0.1 0.5 1.0 0.02 Cyclomethicone 5.00 5.50 5.00 5.50 Dimethicone 1.00 0.60 1.00 0.60 glycerin 1.00 1.20 1.00 1.20 Sodium hydroxides qs qs qs qs preservative 0.30 0.23 0.30 0.23 perfume oil 0.20 0.20 Aqua the. ad 100 ad 100 ad 100 ad 100 Adjust pH to 6.0   OW Sunscreen formulation 1 2 3 4 5 6 7 Glyceryl Stearate SE 0.50 1.00 3.00 1.50 Glycerol Stearate Citrate 2.00 1.00 2.00 4.00 Stearic acid 3.00 2.00 PEG-40 Stearates 0.50 2.00 Cetyl phosphates 1.00 Sodium Cetearyl Sulfate 0.75 Stearyl Alcohol 3.00 2.00 0.60 Cetyl Alcohol 2.50 1.10 1.50 0.60 2.00 VERB. (V) 10.0 0.5 3.0 5.0 0.1 0.02 7.5 Uvinul ^® A Plus ^TM 2.00 1.50 0.75 1.00 2.10 4.50 5.00 Uvasorb® ^® k2A ethylhexyl bis-Isopentylbenzoxazolylphenyl Melamine Ethylhexyl methoxycinnamate Uvinul ^® MC 80 5.00 6.00 8.00 Bis-Ethylhexyloxyphenol Methoxyphenyl Triazines 1.50 2.00 2.50 2.50 Butyl methoxydibenzoylmethane 2.00 2.00 1.50 Disodium phenyl dibenzimidazole tetrasulfonates 2.50 0.50 2.00 0.30 Ethyhexyl Triazone Uvinul ^® T150 4.00 3.00 4.00 2.00 Octocrylene 4.00 7.50 Diethylhexyl butamido triazone 1.00 2.00 1.00 1.00 Phenylbenzimidazole sulfonic acid 0.50 3.00    Methylene bis-benzotriazolyl tetramethylbutylphenol 2.00 0.50 1.50 2.50 Ethyl hexyl salicylates 3.00 5.00 Drometrizole trisiloxanes 0.50 1.00 Terephthalid Dicamphor Sulfonic Acid 1.50 1.00 1.00 0.50 Diethylhexyl 2,6-naphthalate 3.50 7.00 6.00 9.00 Titanium Dioxide microfine 1.00 3.00 3.50 1.50 Zinc oxide microfine 0.25 2.00 C12-15 alkyl benzoates 0.25 4.00 7.00 Dicapryl ether 3.50 2.00 Butylene Glycol Dicaprylate / Dicaprate 5.00 6.00 coco-glycerides 6.00 2.00 Dimethicone 0.50 1.00 2.00 Cyclomethicone 2.00 0.50 0.50 Butyrospermum Parkii (Shea Butter) 2.00 VP / hexadecenes copolymer 0.20 0.50 1.00 glycerin 3.00 7.50 7.50 5.00 2.50 Xanthan gum 0.15 0.05 0.30 Sodium carbomer 0.20 0.15 0.25 Vitamin Ececate 0.60 0.23 0.70 1.00 Biosaccaride gum-1 3.00 10.00 Glycine Soybean (Soybean) Oil 0.50 1.50 1.00 Ethylhexylglycerin 0.30 DMDM hydantoin 0.60 0.40 0.20 Iodopropynyl butyl carbamate 0.18 0.20 methylparaben 0.15 0.25 0.50 phenoxyethanol 1.00 0.40 0.40 0.50 0.40 Trisodium EDTA 0.02 0.05 Tetrasodium iminodisuccinate 0.25 1.00 ethanol 2.00 1.50 3.00 1.20 5.00 perfume oil 0.10 0.25 0.30 0.40 0.20 Aqua the. ad 100 ad 100 ad 100 ad 100 ad 100 ad 100 ad 100     Hydro dispersion 1 2 3 4 5 Ceteaereth-20 1.00 0.50 Cetyl Alcohol 1.00 Sodium carbomer 0.20 0.30 Acrylates / C10-30 Alkyl Acrylate Crosspolymer 0.50 0.40 0.10 0.50 Xanthan gum 0.30 0.15 VERB. (V) 5.0 0.5 3.0 0.1 10.0 Uvinul ^® APlus ^TM 2.00 1.50 0.75 1.00 2.10 Uvasorb® ^® k2A ethylhexyl bis-Isopentylbenzoxazolylphenyl Melamine 3.50 Ethylhexyl methoxycinnamate Uvinul ^® MC 80 5.00 Bis-Ethylhexyloxyphenol Methoxyphenyl Triazines 1.50 2.00 2.50 Butyl methoxydibenzoylmethane 2.00 2.00 Disodium phenyl dibenzimidazole tetrasulfonates 2.50 0.50 2.00 Ethyhexyl Triazone Uvinul ^® T150 4.00 3.00 4.00 Octocrylene 4.00 Diethylhexyl butamido triazone 1.00 2.00 1.00 Phenylbenzimidazole sulfonic acid 0.50 3.00 Methylene bis-benzotriazolyl tetramethylbutylphenol 2.00 0.50 1.50 2.50 Ethyl hexyl salicylates 3.00 Drometrizol Trisiloxane 0.50 Terephthalid Dicamphor Sulfonic Acid 1.50 1.00 1.00 Diethylhexyl 2,6-naphthalate 7.00 9.00 Titanium Dioxide microfine 1.00 3.00 3.50 Zinc oxide microfine 0.25 C12-15 alkyl benzoates 2.00 2.50 Dicapryl ether 4.00 Butylene glycol dicaprylate / dicaprate 4.00 2.00 6.00 Dicapryl carbonates 2.00 6.00 Dimethicone 0.50 1.00 Phenyl trimethicone 2.00 0.50 Butyrospermum Parkii (Shea Butter) 2.00 5.00 VP / hexadecenes copolymer 0.50 0.50 1.00 Tricontanyl PVP 0.50 1.00 Ethylhexylglycerin 1.00 0.80 glycerin 3.00 7.50 7.50 8.50    Glycine Soybean (Soybean) Oil 1.50 1.00 Vitamin E Acetates 0.50 0.25 1.00 glucosylrutin 0.60 0.25 Biosaccaride gum-1 2.50 0.50 2.00 DMDM hydantoin 0.60 0.45 0.25 Iodopropynyl Butylcarbamatec 0.20 methylparaben 0.50 0.25 0.15 phenoxyethanol 0.50 0.40 1.00 Trisodium EDTA 0.01 0.05 0.10 ethanol 3.00 2.00 1.50 7.00 perfume oil 0.20 0.05 0.40 Aqua the. ad 100 ad 100 ad 100 ad 100 ad 100   WHERE Sunscreen emulsion 1 2 3 4 5 Cetyl Dimethicone 2.50 4.00 Polyglyceryl-2 dipolyhydroxystearates 5.00 4.50 PEG-30 dipolyhydroxystearates 5.00 VERB. (V) 5.0 1.0 10.0 0.5 0.1 Uvinul ^® A Plus ^TM 2.00 1.50 0.75 1.00 2.10 Uvasorb® ^® k2A Ethylheyl bis-Isopentylbenzoxazolylphenyl Melamine 2.00 Ethylhexyl methoxycinnamate Uvinul ^® MC 80 5.00 Bis-Ethylhexyloxyphenol Methoxyphenyl Triazines 1.50 2.00 2.50 Butyl methoxydibenzoylmethane 2.00 2.00 Disodium phenyl dibenzimidazole tetrasulfonates 2.50 0.50 2.00 Ethyhexyl Triazone Uvinul ^® T150 4.00 3.00 4.00 Octocrylene 4.00 Diethylhexyl butamido triazone 1.00 2.00 1.00 Phenylbenzimidazole sulfonic acid 0.50 3.00 Methylene bis-benzotriazolyl tetramethylbutylphenol 2.00 0.50 1.50 2.50 Ethyl hexyl salicylates 3.00 Drometrizol Trisiloxane 0.50 Terephthalid Dicamphor Sulfonic Acid 1.50 1.00 1.00 Diethylhexyl 2,6-naphthalate 7.00 4.00    Titanium Dioxide microfine 1.00 3.00 3.50 Zinc oxide microfine 0.25 Mineral oil 12,00 10.00 8.00 C12-15 alkyl benzoates 9.00 Dicaprylyl ether 10.00 7.00 Butylene glycol dicaprylate / dicaprate 2.00 8.00 4.00 Dicaprylyl carbonates 5.00 6.00 Dimethicone 4.00 1.00 5.00 Cyclomethicone 2.00 25,00 2.00 Butyrospermum Parkii (Shea Butter) 3.00 petrolatum 4.50 VP / hexadecenes copolymer 0.50 0.50 1.00 Ethylhexylglycerin 0.30 1.00 0.50 glycerin 3.00 7.50 7.50 8.50 Glycine Soybean (Soybean) Oil 1.00 1.50 1.00 Magnesium Sulfate MgSO4 1.00 0.50 0.50 Magnesium ChlorideMgCl2 1.00 0.70 Vitamin E Acetates 0.50 0.25 1.00 Ascorbyl palmitate 0.50 2.00 Biosaccaride gum-1 3.50 1.00 DMDM hydantoin 0.60 0.40 0.20 methylparaben 0.50 0.25 0.15 phenoxyethanol 0.50 0.40 1.00 Trisodium EDTA 0.12 0.05 0.30 ethanol 3.00 1.50 5.00 perfume oil 0.20 0.40 0.35 Aqua the. ad 100 ad 100 ad 100 ad 100 ad 100   Sticks 1 2 3 4 Caprylic / Capric Triglycerides 12,00 10.00 6.00 octyldodecanol 7.00 14.00 8.00 3.00 Butylene Glycol Dicaprylate / Dicaprate 12,00 Pentaerythrityl tetraisostearate 10.00 6.00 8.00 7.00 Polyglyceryl-3 diisostearate 2.50 Bis-diglyceryl polyacyl adipate-2 9.00 8.00 10.00 8.00 Cetearyl Alcohol 8.00 11.00 9.00 7.00 Myristyl myristate 3.50 3.00 4.00 3.00 Beeswax 5.00 5.00 6.00 6.00    Copernicia Cerifera (Carnauba) Wax 1.50 2.00 2.00 1.50 Cera Alba 0.50 0.50 0.50 0.40 C16-40 alkyl stearates 1.50 1.50 1.50 VERB. (V) 0.5 3.0 1.0 5.0 Uvinul ^® A Plus ^TM 2.00 1.50 0.75 9.00 Uvasorb® ^® k2A ethylhexyl bis-Isopentylbenzoxazolylphenyl Melamine 2.00 4.00 Ethylhexyl methoxycinnamate Uvinul ^® MC 80 3.00 Bis-Ethylhexyloxyphenol Methoxyphenyl Triazines 1.50 2.00 Butyl methoxydibenzoylmethane 2.00 Disodium phenyl dibenzimidazole tetrasulfonates 2.50 0.50 2.00 Ethyhexyl Triazone Uvinul ^® T150 4.00 3.00 4.00 Octocrylene 4.00 Diethylhexyl butamido triazone 1.00 2.00 Phenylbenzimidazole sulfonic acid 0.50 3.00 Methylene bis-benzotriazolyl tetramethylbutylphenol 2.00 0.50 1.50 Ethyl hexyl salicylates 3.00 Drometrizol Trisiloxane 0.50 Terephthalid Dicamphor Sulfonic Acid 1.50 1.00 Diethylhexyl 2,6-naphthalate 7.00 Titanium Dioxide microfine 1.00 3.00 Zinc oxide microfine 0.25 Vitamin E Acetates 0.50 1.00 Ascorbyl palmitate 0.05 0.05 Buxux Chinensis (Jojoba) Oil 2.00 1.00 1.00 Perfume oil, BHT 0.10 0.25 0.35 Ricinus Communis (Castor) Oil ad 100 ad 100 ad 100 ad 100   PIT emulsion 1 2 3 4 5 6 7 8th Glyceryl monostearate SE 0.50 2.00 3.00 5.00 0.50 4.00 Glyceryl isostearates 3.50 4.00 2.00 Isoceteth-20 0.50 2.00 Ceteareth-12 5.00 1.00 3.50 5.00    Ceteareth-20 5.00 1.00 3.50 PEG-100 stearates 2.80 2.30 3.30 Cetyl Alcohol 5.20 1.20 1.00 1.30 0.50 0.30 Cetyl palmitate 2.50 1.20 1.50 0.50 1.50 Cetyl dimethicone copolyol 0.50 1.00 Polyglyceryl-2 dioleate 0.75 0.30 VERB. (V) 0.1 5.0 0.01 0.5 3.0 0.25 10.0 3.0 Uvinul ^® A Plus ^TM 2.00 1.50 0.75 1.00 2.10 4.50 5.00 2.10 Uvasorb® ^® k2A ethylhexyl bis-Isopentylbenzoxazolylphenyl Melamine 4.00 1.50 Ethylhexyl methoxycinnamate Uvinul ^® MC 80 5.00 6.00 8.00 5.00 Bis-ethylhexyloxyphenol methoxyphenyl triazines 1.50 2.00 2.5 2.5 2.5 Butyl methoxydibenzoylmethane 2.00 2.00 1.50 2.00 Disodium phenyl dibenzimidazole tetrasulfonates 2.50 0.50 2.00 0.30 Ethyhexyl Triazone Uvinul ^® T150 4.00 3.00 4.00 2.00 Octocrylene 4.00 7.50 Diethylhexyl butamido triazone 1.00 2.00 1.00 1.00 1.00 Phenylbenzimidazole sulfonic acid 0.50 3.00 Methylene bis-benzotriazolyl tetramethylbutylphenol 2.00 0.50 1.50 2.50 2.50 Ethyl hexyl salicylates 3.00 5.00 Drometrizol Trisiloxane 0.50 1.00 Terephthalylidene Dicamphor Sulfonic Acid 1.50 1.00 1.00 0.50 1.00 Diethylhexyl 2,6-naphthalate 7.00 10.00 7.50 8.00 Titanium Dioxide - microfine 1.00 3.00 3.50 1.50 3.50    C12-15 alkyl benzoates 3.50 6.35 0.10 coco-glycerides 3.00 3.00 1.00 Dicapryl ether 4.50 Dicaprylyl carbonates 4.30 3.00 7.00 Dibutyl adipate 0.50 0.30 Phenyl trimethicone 2.00 3.50 2.00 Cyclomethicone 3.00 C1-5 alkyl galactomannan 0.50 2.00 Hydrogenated Coco-Glycerides 3.00 4.00 Behenoxy Dimethicone 1.50 2.00 VP / hexadecenes copolymer 1.00 1.20 glycerin 4.00 6.00 5.00 8.00 10.00 Vitamin E Acetates 0.20 0.30 0.40 0.30 Butyrospermum Parkii (Shea Butter) 2.00 3.60 2.00 Iodopropyl butyl carbamate 0.12 0.20 Biosaccaride gum-1 0.10 DMDM hydantoin 0.10 0.12 0.13 methylparaben 0.50 0.30 0.35 phenoxyethanol 0.50 0.40 1.00 Ethylhexylglycerin 0.30 1.00 0.35 ethanol 2.00 2.00 5.00 Trisodium EDTA 0.40 0.15 0.20 perfume oil 0.20 0.20 0.24 0.16 0.10 0.10 Aqua the. ad 100 ad 100 ad 100 ad 100 ad 100 ad 100 ad 100 ad 100   Gel Cream 1 2 3 4 Acrylates / C10-30 alkyl acrylate crosspolymer 0.40 0.35 0.40 0.35 Carbomer 0.20 0.22 0.20 0.22 Luvigel® ^® EM 1.50 2.50 2.80 3.50 Xanthan gum 0.10 0.13 0.10 0.13    Cetearyl Alcohol 3.00 2.50 3.00 2.50 C12-15 alkyl benzoates 4.00 4.50 4.00 4.50 Caprylic / Capric Triglycerides 3.00 3.50 3.00 3.50 Titanium Dioxide microfine 1.00 1.50 Zinc oxides - microfine 2.00 0.25 VERB. (V) 0.5 10.0 3.0 5.0 Dihydroxyacetone 3.00 5.00 Cyclomethicone 5.00 5.50 5.00 5.50 Dimethicone 1.00 0.60 1.00 0.60 glycerin 1.00 1.20 1.00 1.20 Sodium hydroxides qs qs qs qs preservative 0.30 0.23 0.30 0.23 perfume oil 0.20 0.20 Aqua the. ad 100 ad 100 ad 100 ad 100 Adjust pH to 6.0   OW Formulations Auto Brown 1 2 3 4 5 6 7 Glyceryl monostearate SE 0.50 1.00 3.00 1.50 Glyceryl Stearate Citrate 2.00 1.00 2.00 4.00 Stearic acid 3.00 2.00 PEG-40 Stearates 0.50 2.00 Cetyl phosphates 1.00 Cetearyl sulfates 0.75 Stearyl Alcohol 3.00 2.00 0.60 Cetyl Alcohol 2.50 1.10 1.50 0.60 2.00 VERB. (V) 0.1 0.5 0,025 5.0 3.0 10.0 1.0 Dihydroxyacetone 3.00 5.00 4 Titanium Dioxide - microfine 1.00 1.50 1.50 Zinc oxides - microfine 0.25 2.00 C12-15 alkyl benzoates 0.25 4.00 7.00 Dicapryl ether 3.50 2.00 Butylene glycol dicaprylate / dicaprate 5.00 6.00 Cocoglycerides 6.00 2.00 Dimethicone 0.50 1.00 2.00 Cyclomethicone 2.00 0.50 0.50 Butyrospermum Parkii (Shea) butter 2.00    VP / hexadecenes copolymer 0.20 0.50 1.00 glycerin 3.00 7.50 7.50 5.00 2.50 Xanthan gum 0.15 0.05 0.30 Sodium carbomer 0.20 0.15 0.25 Vitamin E Acetates 0.60 0.23 0.70 1.00 Biosaccaride gum-1 3.00 10.00 Glycine Soybean (Soybean) Oil 0.50 1.50 1.00 Ethylhexylglycerin 0.30 DMDM hydantoin 0.60 0.40 0.20 Iodopropynyl Butylcarbamatec 0.18 0.20 methylparaben 0.15 0.25 0.50 phenoxyethanol 1.00 0.40 0.40 0.50 0.40 Trisodium EDTA 0.02 0.05 Tetrasodium iminodisuccinate 0.25 1.00 ethanol 2.00 1.50 3.00 1.20 5.00 perfume oil 0.10 0.25 0.30 0.40 0.20 Aqua the. ad 100 ad 100 ad 100 ad 100 ad 100 ad 100 ad 100   OW Make Up 1 2 3 4 5 6 7 Glyceryl monostearate SE 0.50 1.00 3.00 1.50 Glycerol Stearate Citrate 2.00 1.00 2.00 4.00 Stearic acid 3.00 2.00 PEG-40 Stearates 0.50 2.00 Cetyl phosphates 1.00 Cetearyl sulfates 0.75 Stearyl Alcohol 3.00 2.00 0.60 Cetyl Alcohol 2.50 1.10 1.50 0.60 2.00 VERB. (V) 3.0 5.0 2.0 0.5 1.0 5.0 10.0 Titanium dioxides 10.00 12,00 9.00 8.50 11.00 9.50 10.00 Iron Oxide 2.00 4.00 3.00 5.00 3.40 6.00 4.40 Zinc oxides 4.00 2.00 3.00 C12-15 alkyl benzoates 0.25 4.00 7.00 Dicapryl ether 3.50 2.00 Butylene glycol dicaprylate / dicaprate 5.00 6.00    Cocoglycerides 6.00 2.00 Dimethicone 0.50 1.00 2.00 Cyclomethicone 2.00 0.50 0.50 Butyrospermum Parkii (Shea Butter) 2.00 VP / hexadecenes copolymer 0.20 0.50 1.00 glycerin 3.00 7.50 7.50 5.00 2.50 Xanthan gum 0.15 0.05 0.30 Sodium carbomer 0.20 0.15 0.25 Vitamin E Acetates 0.60 0.23 0.70 1.00 Glycine Soybean (Soybean) Oil 0.50 1.50 1.00 Ethylhexylglycerin 0.30 DMDM hydantoin 0.60 0.40 0.20 Iodopropynyl Butylcarbamatec 0.18 0.20 methylparaben 0.15 0.25 0.50 phenoxyethanol 1.00 0.40 0.40 0.50 0.40 Trisodium EDTA 0.02 0.05 Tetrasodium iminodisuccinate 0.25 1.00 ethanol 2.00 1.50 3.00 1.20 5.00 perfume oil 0.10 0.25 0.30 0.40 0.20 Aqua the. ad 100 ad 100 ad 100 ad 100 ad 100 ad 100 ad 100   Hydrodispersion self-tanner 1 2 3 4 5 Ceteaereth-20 1.00 0.50 Cetyl Alcohol 1.00 Luvigel® ^® EM 2.00 2.50 2.00 Acrylates / C10-30 Alkyl Acrylate Crosspolymer 0.50 0.40 0.10 0.50 Xanthan gum 0.30 0.15 VERB. (V) 3.0 1.0 0.5 0.1 5.0 Dihydroxyacetone 3.00 5.00 Uvinul ^® A Plus ^TM 2.00 1.50 0.75 1.00 2.10 Titanium Dioxide - microfine 1.00 1.00 1.00 Zinc oxides - microfine 1.90 0.25 C12-15 alkyl benzoates 2.00 2.50 Dicapryl ether 4.00    Butylene glycol dicaprylate / dicaprate 4.00 2.00 6.00 Dicapryl carbonates 2.00 6.00 Dimethicone 0.50 1.00 Phenyl trimethicone 2.00 0.50 Butyrospermum Parkii (Shea Butter) 2.00 5.00 VP / hexadecenes copolymer 0.50 0.50 1.00 Tricontanyl PVP 0.50 1.00 Ethylhexylglycerin 1.00 0.80 glycerin 3.00 7.50 7.50 8.50 Glycine Soybean (Soybean) Oil 1.50 1.00 Vitamin E Acetates 0.50 0.25 1.00 glucosylrutin 0.60 0.25 DMDM hydantoin 0.60 0.45 0.25 Iodopropynyl Butylcarbamatec 0.20 methylparaben 0.50 0.25 0.15 phenoxyethanol 0.50 0.40 1.00 Trisodium EDTA 0.01 0.05 0.10 ethanol 3.00 2.00 1.50 7.00 perfume oil 0.20 0.05 0.40 Aqua the. ad 100 ad 100 ad 100 ad 100 ad 100   Hydrodispersion after sun 1 2 3 4 5 Ceteaereth-20 1.00 0.50 Cetyl Alcohol 1.00 Luvigel® ^® EM 2.00 2.50 2.00 Acrylates / C10-30 Alkyl Acrylate Crosspolymer 0.50 0.30 0.40 0.10 0.50 Xanthan gum 0.30 0.15 VERB. (V) 0.1 5.0 0.5 3.0 1.0 C12-15 alkyl benzoates 2.00 2.50 Dicapryl ether 4.00 Butylene glycol dicaprylate / dicaprate 4.00 2.00 6.00 Dicapryl carbonates 2.00 6.00 Dimethicone 0.50 1.00 Phenyl trimethicone 2.00 0.50 Tricontanyl PVP 0.50 1.00 Ethylhexylglycerin 1.00 0.80 glycerin 3.00 7.50 7.50 8.50    Glycine Soybean (Soybean) Oil 1.50 1.00 Vitamin E Acetates 0.50 0.25 1.00 glucosylrutin 0.60 0.25 Trisodium EDTA 0.01 0.05 0.10 ethanol 15.00 10.00 8.00 12,00 9.00 perfume oil 0.20 0.05 0.40 Aqua the. ad 100 ad 100 ad 100 ad 100 ad 100   WO-emulsion 1 2 3 4 5 Cetyl Dimethicone 2.50 4.00 Polyglyceryl-2 dipolyhydroxystearates 5.00 4.50 PEG-30Dipolyhydroxystearate 5.00 VERB. (V) 5.0 10.0 0.1 0.5 1.0 Uvinul ^® A Plus ^TM 2.00 1.50 0.75 1.00 2.10 Titanium Dioxide microfine 1.00 3.00 3.50 Zinc oxide microfine 0.90 0.25 Minera Oil 12,00 10.00 8.00 C12-15 alkyl benzoates 9.00 Dicaprylyl ether 10.00 7.00 Butylene glycol dicaprylate / dicaprate 2.00 8.00 4.00 Dicaprylyl carbonates 5.00 6.00 Dimethicone 4.00 1.00 5.00 Cyclomethicone 2.00 25,00 2.00 Butyrospermum Parkii (Shea Butter) 3.00 petrolatum 4.50 VP / hexadecenes copolymer 0.50 0.50 1.00 Ethylhexylglycerin 0.30 1.00 0.50 glycerin 3.00 7.50 7.50 8.50 Glycine Soybean (Soybean) Oil 1.00 1.50 1.00 Magnesium sulphates 1.00 0.50 0.50 Magnesium chlorides 1.00 0.70 Vitamin E Acetates 0.50 0.25 1.00 Ascorbyl palmitate 0.50 2.00 Biosaccaride gum-1 3.50 7.00 DMDM hydantoin 0.60 0.40 0.20 methylparaben 0.50 0.25 0.15 phenoxyethanol 0.50 0.40 1.00 Trisodium EDTA 0.12 0.05 0.30 ethanol 3.00 1.50 5.00 perfume oil 0.20 0.40 0.35 Aqua the. ad 100 ad 100 ad 100 ad 100 ad 100    Solid stabilized emulsion (Pickering emulsion) 1 2 3 4 5 Mineral oil 16.00 16.00 octyldodecanol 9.00 9.00 5.00 Caprylic / Capric Triglycerides 9.00 9.00 6.00 C12-15 alkyl benzoates 5.00 8.00 Butylene Glycol Dicaprylate / Dicaprate 8.00 Dicaprylyl ether 9.00 4.00 Dicaprylyl carbonates 9.00 Hydroxy octacosanyl hydroxystearates 2.00 2.00 2.20 2.50 1.50 Disteardimonium hectorite 1.00 0.75 0.50 0.25 Cera Microcristallina + Paraffinum Liquidum 0.35 5.00 Hydroxypropyl methyl cellulose 0.10 0.05 Dimethicone 3.00 VERB. (V) 1.0 0.5 0.1 3.0 5.0 Titanium Dioxide + Alumina + Simethicone + Aqua 3.00 Titanium Dioxide + Trimethoxycaprylylsilane 2.00 4.00 2.00 4.00 Silica dimethyl silylates 2.50 6.00 2.50 Boron Nitride 1.00 Strong / -Natriummetaphosphat polymer 2.00 Tapioca Starch 0.50 Sodium Chloride 5.00 7.00 8.50 3.00 4.50 glycerin 1.00 Trisodium EDTA 1.00 1.00 1.00 1.00 1.00 Vitamin E Acetates 5.00 10.00 3.00 6.00 10.00 Ascorbyl palmitate 1.00 1.00 1.00 methylparaben 0.60 0.20 Propylparaben 0.20 phenoxyethanol 0.20 Hexamidine diisethionate 0.40 0.50 0.40 Diazolidinyl urea 0.08 ethanol 0.23 0.20 perfume oil 5.00 3.00 4.00 Aqua the. 0.20 0.30 0.10 ad 100 ad 100 ad 100 ad 100 ad 100    Sticks 1 2 3 4 Caprylic / Capric Triglycerides 12,00 10.00 6.00 octyldodecanol 7, 00 14.00 8.00 3.00 Butylene Glycol Dicaprylate / Dicaprate 12,00 Pentaerythrityl tetraisostearate 10.00 6.00 8.00 7.00 Polyglyceryl-3 diisostearate 2.50 Bis-diglyceryl polyacyl adipate-2 9.00 8.00 10.00 8.00 Cetearyl Alcohol 8.00 11.00 9.00 7.00 Myristyl myristate 3.50 3.00 4.00 3.00 Beeswax 5.00 5.00 6.00 6.00 Copernicia Cerifera (Carnauba) Wax 1.50 2.00 2.00 1.50 Cera Aiba 0.50 0.50 0.50 0.40 C16-40 alkyl stearates 1.50 1.50 1.50 VERB. (V) 10.0 1.0 3.0 0.1 Uvinul ^® A Plus ^TM 2.00 1.50 0.75 9.00 Titanium Dioxide - microfine 1.00 3.00 Zinc oxides - microfine 1.00 0.25 Vitamin E Acetates 0.50 1.00 Ascorbyl palmitate 0.05 0.05 Buxux Chinensis (Jojoba) Oil 2.00 1.00 1.00 Perfume oil, BHT 0.10 0.25 0.35 Ricinus Communis (Castor) Oil ad 100 ad 100 ad 100 ad 100   PIT emulsions self-tanner 1 2 3 4 5 6 7 8th Glyceryl monostearate SE 0.50 2.00 3.00 5.00 0.50 4.00 Glyceryl isostearates 3.50 4.00 2.00 Isoceteth-20 0.50 2.00 qCeteareth-12 5.00 1.00 3.50 5.00 Ceteareth-20 5.00 1.00 3.50 PEG-100 stearates 2.80 2.30 3.30 Cetyl Alcohol 5.20 1.20 1.00 1.30 0.50 0.30 Cetyl palmitate 2.50 1.20 1.50 0.50 1.50 Cetyl dimethicone copolyol 0.50 1.00    Polyglyceryl-2 0.75 0.30 VERB. (V) 0.1 0.5 0.01 5.0 0.5 3.0 0,025 10.0 dihydroxyacetone 3.00 5.00 4.00 Uvinul ^® A Plus ^TM 2.00 1.50 0.75 1.00 2.10 4.50 5.00 2.10 Titanium Dioxide - microfine 1.00 1.50 3.50 1.50 1.00 Zinc oxides - microfine 1.00 0.25 2.00 1.50 C12-15 alkyl benzoates 3.50 6.35 0.10 Cocoglycerides 3.00 3.00 1.00 Dicapryl ether 4.50 Dicaprylyl carbonates 4.30 3.00 7.00 Dibutyl adipate 0.50 0.30 Phenyl trimethicone 2.00 3.50 2.00 Cyclomethicone 3.00 C1-5 alkyl galactomannan 0.50 2.00 Hydrogenated Coco-Glycerides 3.00 4.00 Behenic dimethicone 1.50 2.00 VP / hexadecenes copolymer 1.00 1.20 glycerin 4.00 6.00 5.00 8.00 10.00 Vitamin E Acetates 0.20 0.30 0.40 0.30 Butyrosperumu Parkii (Shea Butter) 2.00 3.60 2.00 Iodopropyl butyl carbamate 0.12 0.20 DMDM hydantoin 0.10 0.12 0.13 methylparaben 0.50 0.30 0.35 phenoxyethanol 0.50 0.40 1.00 Ethylhexylglycerin 0.30 1.00 0.35 ethanol 2.00 2.00 5.00 Trisodium EDTA 0.40 0.15 0.20 perfume oil 0.20 0.20 0.24 0.16 0.10 0.10 Aqua the. ad 100 ad 100 ad 100 ad 100 ad 100 ad 10 0 ad 100 ad 100   oil gel 1 2 3 4 Caprylic / Capric Triglycerides 12,00 10.00 6.00 octyldodecanol 7, 00 14.00 8.00 3.00 Butylene Glycol Dicaprylate / Dicaprate 12,00 Pentaerythrityl tetraisostearate 10.00 6.00 8.00 7.00 Polyglyceryl-3 diisostearate 2.50 Bis-diglyceryl polyacyl adipate-2 9.00 8.00 10.00 8.00 Myristyl myristate 3.50 3.00 4.00 3.00 Quaternium-18 Bentonite 5.00 5.00 6.00 6.00 Propylene carbonates 15.00 20.00 18,00 19.50 VERB. (V) 1.0 0.5 3.0 5.0 Vitamin E Acetates 0.50 1.00 Ascorbyl palmitate 0.05 0.05 Buxus Chinensis (Jojoba) Oil 2.00 1.00 1.00 Perfume oil, BHT 0.10 0.25 0.35 Ricinus Communis (Castor) Oil ad 100 ad 100 ad 100 ad 100  

Example 38:

In the following formulas are cosmetic sunscreen preparations, containing a combination of at least one inorganic pigment, preferably zinc oxide and / or titanium dioxide and organic UV-A and UV-B filter and the example 1 produced VERB. (V) described. Said VERB. (V) is in the following examples as VERB. (V). The verb. (V) becomes representative of all others in the following examples VERB. (V) used. It goes without saying for the expert that all other active ingredients mentioned prepared according to Example 1 and can be used in the preparations mentioned below.

The Preparation of the following formulations takes place on conventional, the art known manner.

The content of VERB. (V) refers to 100%. The VERB according to the invention. (V) can be used both in a pure form and as an oily solution. In the case of the oily solution, the content of oil must be the. be adapted in the respective formulation. A 7.50 Uvinul MC 80 Ethyl hexyl cinnamate 2,00 Uvinul M 40 Benzophenone-3 0.80 Rylo PG 11 Polyglyceryl Dimer Soyate 1,00 Span 60 Sorbitan Stearate 0.50 vitamin E acetate Tocopheryl acetate 3.00 Dracorin 100 SE Glyceryl Stearate, PEG-100 Stearate 1.00 Cremophor CO 410 PEG-40 Hydrogenated Castor Oil B 3.00 T-Lite SF Titanium Dioxide, Alumina Hydrate, Dimethicone / Methicone Copolymer 1.00 Cetiol SB 45 Butyrospermum Parkii (Shea Butter) 6.50 Finsolv TN C12-15 alkyl benzoates C 5.00 butylene glycol Butylene glycol 0.30 Keltrol Xanthan gum 0.10 Edeta BD Disodium EDTA 0.10 allantoin allantoin 66.20 water to the. Aqua the. D 1.00 Sea urchin 305 Polyacrylamide, C13-14 isoparaffin, laureth-7 1% VERB. (V) qs preservative A 7.50 Uvinul MC 80 Ethyl hexyl cinnamate 2,00 Uvinul M 40 Benzophenone-3 0.80 Rylo PG 11 Polyglyceryl Dimer Soyate 1,00 Span 60 Sorbitan Stearate 0.50 vitamin E acetate Tocopheryl acetate 3.00 Dracorin 100 SE Glyceryl Stearate, PEG-100 Stearate 1.00 Cremophor CO 410 PEG-40 Hydrogenated Castor Oil B 3.00 Z-COTE MAX Zinc Oxide (and) Diphenyl Capryl Methicone 1.00 Cetiol SB 45 Butyrospermum Parkii (Shea Butter) 6.50 Finsolv TN C12-15 alkyl benzoates C 5.00 butylene glycol Butylene glycol 0.30 Keltrol Xanthan gum 0.10 Edeta BD Disodium EDTA 0.10 allantoin allantoin 66.20 water to the. Aqua the. D 2,00 Simulgel NS Hydroxyethyl acrylate / sodium acryloyl dimethyl taurate copolymer, squalane, polysorbate 60 1% VERB. (V) qs preservative A 7.50 Uvinul MC 80 Ethyl hexyl cinnamate 2.00 Uvinul A Plus Diethylamino hydroxybenzoyl hexyl benzoate 0.80 Rylo PG 11 Polyglyceryl Dimer Soyate 1,00 Span 60 Sorbitan Stearate 0.50 vitamin E acetate Tocopheryl acetate 3.00 Dracorin 100 SE Glyceryl Stearate, PEG-100 Stearate 1.00 Cremophor CO 410 PEG-40 Hydrogenated Castor Oil B 3.00 Z-COTE MAX Zinc Oxide (and) Diphenyl Capryl Methicone 1.00 Cetiol SB 45 Butyrospermum Parkii (Shea Butter) 6.50 Finsolv TN C12-15 alkyl benzoates C 5.00 butylene glycol Butylene glycol 0.30 Keltrol Xanthan gum 0.10 Edeta BD Disodium EDTA 0.10 allantoin allantoin 66.20 water to the. Aqua the. D 2,00 Simulgel NS Hydroxyethyl acrylate / sodium acryloyl dimethyl taurate copolymer, squalane, polysorbate 60 1% VERB. (V) qs preservative A 4,00 Uvinul MC 80 Ethyl hexyl cinnamate 2.00 Uvinul T 150 Ethyl hexyl triazone 2.00 Uvinul A Plus Diethylamino hydroxybenzoyl hexyl benzoate 0.80 Rylo PG 11 Polyglyceryl Dimer Soyate 1,00 Span 60 Sorbitan Stearate 0.50 vitamin E acetate Tocopheryl acetate 3.00 Dracorin 100 SE Glyceryl Stearate, PEG-100 Stearate 1.00 Cremophor CO 410 PEG-40 Hydrogenated Castor Oil B 3.00 Z-COTE MAX Zinc Oxide (and) Diphenyl Capryl Methicone 1.00 Cetiol SB 45 Butyrospermum Parkii (Shea Butter) 6.50 Finsolv TN C12-15 alkyl benzoates C 5.00 butylene glycol Butylene glycol 0.30 Keltrol Xanthan gum 0.10 Edeta BD Disodium EDTA 0.10 allantoin allantoin 66.20 water to the. Aqua the. D 2,00 Simulgel NS Hydroxyethyl Acrylate / Sodium Acryloylodimethyl Taurate Copolymer, Squalane, Polysorbate 60 1% VERB. (V) qs preservative A 4,00 Uvinul MC 80 Ethyl hexyl cinnamate 2.00 Uvinul T 150 Ethyl hexyl triazone 2.00 Uvinul A Plus Diethylamino hydroxybenzoyl hexyl benzoate 0.80 Rylo PG 11 Polyglyceryl Dimer Soyate 1,00 Span 60 Sorbitan Stearate 0.50 vitamin E acetate Tocopheryl acetate 3.00 Dracorin 100 SE Glyceryl Stearate, PEG-100 Stearate 1.00 Cremophor CO 410 PEG-40 Hydrogenated Castor Oil B 3.00 T-sheet SF Titanium Dioxide, Alumina Hydrate, Dimethicone / Methicone Copolymer 1.00 Cetiol SB 45 Butyrospermum Parkii (Shea Butter) 6.50 Finsolv TN C12-15 alkyl benzoates C 5.00 butylene glycol Butylene glycol 0.30 Keltrol Xanthan gum 0.10 Edeta BD Disodium EDTA 0.10 allantoin allantoin 66.20 water to the. Aqua the. D 2,00 Simulgel NS Hydroxyethyl acrylate / sodium acryloyl dimethyl taurate copolymer, squalane, polysorbate 60 1% VERB. (V) qs preservative A 4,00 Uvinul MC 80 Ethyl hexyl cinnamate 2.00 Uvinul T 150 Ethyl hexyl triazone 2.00 Uvinul A Plus Diethylamino hydroxybenzoyl hexyl benzoate 0.80 Rylo PG 11 Polyglyceryl Dimer Soyate 1,00 Span 60 Sorbitan Stearate 0.50 vitamin E acetate Tocopheryl acetate 3.00 Dracorin 100 SE Glyceryl Stearate, PEG-100 Stearate 1.00 Cremophor CO 410 PEG-40 Hydrogenated Castor Oil B 3.00 Z-COTE MAX Zinc Oxide (and) Diphenyl Capryl Methicone 1.00 Cetiol SB 45 Butyrospermum Parkii (Shea Butter) 6.50 Finsolv TN C12-15 alkyl benzoates C 5.00 butylene glycol Butylene glycol 0.30 Keltrol Xanthan gum 0.10 Edeta BD Disodium EDTA 0.10 allantoin allantoin 66.20 water to the. Aqua the. D 2,00 Simulgel NS Hydroxyethyl acrylate / sodium acryloyl dimethyl taurate copolymer, squalane, polysorbate 60 1% VERB. (V) qs preservative A 4,00 Uvinul MC 80 Ethyl hexyl cinnamate 1.00 Uvinul T 150 Ethyl hexyl triazone 2.00 Parsol 1789 Butyl methoxydibenzoylmethane 0.80 Rylo PG 11 Polyglyceryl Dimer Soyate 1,00 Span 60 Sorbitan Stearate 0.50 vitamin E acetate Tocopheryl acetate 3.00 Dracorin 100 SE Glyceryl Stearate, PEG-100 Stearate 1.00 Cremophor CO 410 PEG-40 Hydrogenated Castor Oil B 3.00 T-Lite SF-S Titanium Dioxide, Silica Hydrate, Alumina Hydrate, Methicone / Dimethicone Copolymer 1.00 Cetiol SB 45 Butyrospermum Parkii (Shea Butter) 6.50 Finsolv TN C12-15 alkyl benzoates C 5.00 butylene glycol Butylene glycol 0.30 Keltrol Xanthan gum 0.10 Edeta BD Disodium EDTA 0.10 allantoin allantoin 66.70 water to the. Aqua the. D 2,00 Simulgel NS Hydroxyethyl acrylate / sodium acryloyl dimethyl taurate copolymer, squalane, polysorbate 60 0.5% VERB. (V) qs preservative A 4,00 Uvinul MC 80 Ethyl hexyl cinnamate 1.00 Uvinul T 150 Ethyl hexyl triazone 2.00 Parsol 1789 Butyl methoxydibenzoylmethane 0.80 Rylo PG 11 Polyglyceryl Dimer Soyate 1,00 Span 60 Sorbitan Stearate 0.50 vitamin E acetate Tocopheryl acetate 3.00 Dracorin 100 SE Glyceryl Stearate, PEG-100 Stearate 1.00 Cremophor CO 410 PEG-40 Hydrogenated Castor Oil B 3.00 Z-COTE MAX Zinc Oxide (and) Diphenyl Capryl Methicone 1.00 Cetiol SB 45 Butyrospermum Parkii (Shea Butter) 6.50 Finsolv TN C12-15 alkyl benzoates C 5.00 butylene glycol Butylene glycol 0.30 Keltrol Xanthan gum 0.10 Edeta BD Disodium EDTA 0.10 allantoin allantoin 67.10 water. Aqua the. D 2,00 Simulgel NS Hydroxyethyl acrylate / sodium acryloyl dimethyl taurate copolymer, squalane, polysorbate 60 0.1% VERB. (V) qs preservative A 5,00 Uvinul N 539 T Octocrylene 2.00 Parsol 1789 Butyl methoxydibenzoylmethane 0.80 Rylo PG 11 Polyglyceryl Dimer Soyate 1,00 Span 60 Sorbitan Stearate 0.50 vitamin E acetate Tocopheryl acetate 3,00 Dracoirn 100 SE Glyceryl Stearate, PEG-100 Stearate 1.00 Cremophor CO 410 PEG-40 Hydrogenated Castor Oil B 3.00 T-Lite SF-S Titanium Dioxide, Silica Hydrate, Alumina Hydrate, Methicone / Dimethicone Copolymer 1.00 Cetiol SB 45 Butyrospermum Parkii (Shea Butter) 6.50 Finsolv TN C12-15 alkyl benzoates C 5.00 butylene glycol Butylene glycol 0.30 Keltrol Xanthan gum 0.10 Edeta BD Disodium EDTA 0.10 allantoin allantoin 66.20 water to the. Aqua the. D 2,00 Simulgel NS Hydroxyethyl acrylate / sodium acryloyl dimethyl taurate copolymer, squalane, polysorbate 60 1% VERB. (V) qs preservative A 5,00 Uvinul N 539 T Octocrylene 2.00 Uvinul A Plus Diethylamino hydroxybenzoyl hexyl benzoate 0.80 Rylo PG 11 Polyglyceryl Dimer Soyate 1,00 Span 60 Sorbitan Stearate 0.50 vitamin E acetate Tocopheryl acetate 3.00 Dracorin 100 SE Glyceryl Stearate, PEG-100 Stearate 1.00 Cremophor CO 410 PEG-40 Hydrogenated Castor Oil B 3.00 T-Lite SF Titanium Dioxide, Alumina Hydrate, Dimethicone / Methicone Copolymer 1.00 Cetiol SB 45 Butyrospermum Parkii (Shea Butter) 6.50 Finsolv TN C12-15 alkyl benzoates C 5.00 butylene glycol Butylene glycol 0.30 Keltrol Xanthan gum 0.10 Edeta BD Disodium EDTA 0.10 allantoin allantoin 65.20 water to the. Aqua the. D 2,00 Simulgel NS Hydroxyethyl acrylate / sodium acryloyl dimethyl taurate copolymer, squalane, polysorbate 60 2% VERB. (V) qs preservative A 5,00 Uvinul N 539 T Octocrylene 2.00 Uvinul A Plus Diethylamino hydroxybenzoyl hexyl benzoate 0.80 Rylo PG 11 Polyglyceryl Dimer Soyate 1,00 Span 60 Sorbitan Stearate 0.50 vitamin E acetate Tocopheryl acetate 3.00 Dracorin 100 SE Glyceryl Stearate, PEG-100 Stearate 1,00 Cremophor 00 410 PEG-40 Hydrogenated Castor Oil B 3.00 Z-COTE MAX Zinc Oxide (and) Diphenyl Capryl Methicone 1.00 Cetiol SB 45 Butyrospermum Parkii (Shea Butter) 6.50 Finsolv TN C12-15 alkyl benzoates C 5.00 butylene glycol Butylene glycol 0.30 Keltrol Xanthan gum 0.10 Edeta BD Disodium EDTA 0.10 allantoin allantoin 66.70 water to the. Aqua the. D 2,00 Simulgel NS Hydroxyethyl acrylate / sodium acryloyl dimethyl taurate copolymer, squalane, polysorbate 60 0.5% VERB. (V) qs preservative A 5,00 Uvinul N 539 T Octocrylene 2.00 Uvinul A Plus Diethylamino hydroxybenzoyl hexyl benzoate 0.80 Rylo PG 11 Polyglyceryl Dimer Soyate 1,00 Span 60 Sorbitan Stearate 0.50 vitamin E acetate Tocopheryl acetate 3.00 Dracorin 100 SE Glyceryl Stearate, PEG-100 Stearate 1.00 Cremophor CO 410 PEG-40 Hydrogenated Castor Oil B 3.00 Z-COTE MAX Zinc Oxide (and) Diphenyl Capryl Methicone 1.00 Cetriol SB 45 Butyrospermum Parkii (Shea Butter) 6.50 Finsolv TN C12-15 alkyl benzoates C 5.00 butylene glycol Butylene glycol 0.30 Keltrol Xanthan gum 0.10 Edeta BD Disodium EDTA 0.10 allantoin allantoin 2.0 Mexoryl SX Terephthalidene Dicamphor Sulfonic Acid 66.20 water to the. Aqua the. D 2,00 Simulgel NS Hydroxyethyl acrylate / sodium acryloyl dimethyl taurate copolymer, squalane, polysorbate 60 1% VERB. (V) qs preservative A 5,00 Uvinul N 539 T Octocrylene 2.00 Uvinul A Plus Diethylamino hydroxybenzoyl hexyl benzoate 0.80 Rylo PG 11 Polyglyceryl Dimer Soyate 1,00 Span 60 Sorbitan Stearate 0.50 vitamin E acetate Tocopheryl acetate 3.00 Dracorin 100 SE Glyceryl Stearate, PEG-100 Stearate 1.00 Cremophor CO 410 PEG-40 Hydrogenated Castor Oil B 3.00 Z-COTE MAX Zinc Oxide (and) Diphenyl Capryl Methicone 1.00 Cetriol SB 45 Butyrospermum Parkii (Shea Butter) 6.50 Finsolv TN C12-15 alkyl benzoates C 5.00 butylene glycol Butylene glycol 0.30 Keltrol Xanthan gum 0.10 Edeta BD Disodium EDTA 0.10 allantoin allantoin 2.0 Mexoryl SX Terephthalidene Dicamphor Sulfonic Acid 65.20 water to the. Aqua the. D 2,00 Simulgel NS Hydroxyethyl acrylate / sodium acryloyl dimethyl taurate copolymer, squalane, polysorbate 60 2% VERB. (V) qs preservative A 5,00 Uvinul N 539 T Octocrylene 2.00 Uvinul A Plus Diethylamino hydroxybenzoyl hexyl benzoate 0.80 Rylo PG 11 Polyglyceryl Dimer Soyate 1,00 Span 60 Sorbitan Stearate 0.50 vitamin E acetate Tocopheryl acetate 3.00 Dracorin 100 SE Glyceryl Stearate, PEG-100 Stearate 1.00 Cremophor CO 410 PEG-40 Hydrogenated Castor Oil B 3.00 Z-COTE MAX Zinc Oxide (and) Diphenyl Capryl Methicone 1.00 Cetriol SB 45 Butyrospermum Parkii (Shea Butter) 6.50 Finsolv TN C12-15 alkyl benzoates C 5.00 butylene glycol Butylene glycol 0.30 Keltrol Xanthan gum 0.10 Edeta BD Disodium EDTA 0.10 allantoin allantoin 67.10 water. Aqua the. D 2,00 Simulgel NS Hydroxyethyl acrylate / sodium acryloyl dimethyl taurate copolymer, squalane, polysorbate 60 0.1% VERB. (V) qs preservative A 5,00 Uvinul N 539 T Octocrylene 2.00 Uvinul A Plus Diethylamino hydroxybenzoyl hexyl benzoate 0.80 Rylo PG 11 Polyglyceryl Dimer Soyate 1,00 Span 60 Sorbitan Stearate 0.50 vitamin E acetate Tocopheryl acetate 3.00 Dracorin 100 SE Glyceryl Stearate, PEG-100 Stearate 1.00 Cremophor CO 410 PEG-40 Hydrogenated Castor Oil B 3.00 Z-COTE MAX Zinc Oxide (and) Diphenyl Capryl Methicone 1.00 Cetriol SB 45 Butyrospermum Parkii (Shea Butter) 6.50 Finsolv TN C12-15 alkyl benzoates C 5.00 butylene glycol Butylene glycol 0.30 Keltrol Xanthan gum 0.10 Edeta BD Disodium EDTA 0.10 allantoin allantoin 66.20 water to the. Aqua the. D 2,00 Simulgel NS Hydroxyethyl acrylate / sodium acryloyl dimethyl taurate copolymer, squalane, polysorbate 60 1% VERB. (V) qs preservative A 7.50 Uvinul MC 80 Ethylhexyl methoxycinnamate 5,00 Uvinul N 539 Octocrylene 3.00 Emulgade PL 68/50 Cetearyl Glucoside, Cetearyl Alcohol 2.00 Dracorin 100 SE Glyceryl Stearate, PEG-100 Stearate 1.00 Fitoderm Squalane 0.50 Cremophore WO 7 PEG-7 Hydrogenated Castor Oil 0.50 Cremophor PS 20 Polysorbate 20 2.00 Dry Flo Pure Aluminum Starch Octenylsuccinate B 5.00 Z-COTE MAX Zinc Oxide (and) Diphenyl Capryl Methicone C 4.00 1,2-propylene glycol Care Propylene glycol 0.20 Keltrol Xanthan gum 0,50 Simulgel 600 Acrylamide / sodium acryloyldimethyltaurate copolymer, isohexadecane, polysorbate 80 Add 100 water to the. Aqua the. qs preservative 0.50 vitamin E acetate Tocopheryl acetate 2% VERB. (V) 1,00 RetiSTAR Caprylic / Capric Triglycerides, Sodium Ascorbate, Tocopherol, Retinol A 7.50 Uvinul MC 80 Ethylhexyl methoxycinnamate 2.00 Uvinul N 539 T Octocrylene 3.00 Emulgade PL 68/50 Cetearyl Glucoside, Cetearyl Alcohol 2.00 Dracorin 100 SE Glyceryl Stearate, PEG-100 Stearate 1.00 Fitoderm Squalane 0.50 Cremophore WO 7 PEG-7 Hydrogenated Castor Oil 0.50 Cremophor PS 20 Polysorbate 20 2.00 Dry Flo Pure Aluminum Starch Octenylsuccinate B 5.00 T-Lite SF-S Titanium Dioxide, Silica Hydrate, Alumina Hydrate, Methicone / Dimethicone Copolymer C 4.00 1,2-propylene glycol Care Propylene glycol 0.20 Keltrol Xanthan gum 0,50 Simulgel 600 Acrylamide / sodium acryloyldimethyltaurate copolymer, isohexadecane, polysorbate 80 Add 100 water to the. Aqua the. qs preservative 0.50 vitamin E acetate Tocopheryl acetate 1% VERB. (V) 2.00 RetiSTAR Caprylic / Capric Triglycerides, Sodium Ascorbate, Tocopherol, Retinol A 7.50 Uvinul MC 80 Ethylhexyl methoxycinnamate 5,00 Uvinul N 539 T Octocrylene 3.00 Emulgade PL 68/50 Cetearyl Glucoside, Cetearyl Alcohol 2.00 Dracorin 100 SE Glyceryl Stearate, PEG-100 Stearate 1.00 Fitoderm Squalane 0.50 Cremophore WO 7 PEG-7 Hydrogenated Castor Oil 0.50 Cremophor PS 20 Polysorbate 20 2.00 Dry Flo Pure Aluminum Starch Octenylsuccinate B 5.00 T-Lite SF-S Titanium Dioxide, Silica Hydrate, Alumina Hydrate, Methicone / Dimethicone Copolymer C 4.00 1,2-propylene glycol Care Propylene glycol 1.0 D-panthenol 50 P Penthenol, Propylene glycol 0.20 Keltrol Xanthan gum 0,50 Simulgel 600 Acrylamide / sodium acryloyldimethyltaurate copolymer, isohexadecane, polysorbate 80 Add 100 water to the. Aqua the. qs preservative 0.50 vitamin E acetate Tocopheryl acetate 1% VERB. (V) 1,00 RetiSTAR Caprylic / Capric Triglycerides, Sodium Ascorbate, Tocopherol, Retinol A 5,50 Uvinul MC 80 Ethylhexyl methoxycinnamate 2.00 Uvinul A Plus Diethylamino hydroxybenzoyl hexyl benzoate 3.00 Uvinul N 539 T Octocrylene 3.00 Emulgade PL 68/50 Cetearyl Glucoside, Cetearyl Alcohol 2.00 Dracorin 100 SE Glyceryl Stearate, PEG-100 Stearate 1.00 Fitoderm Squalane 0.50 Cremophore WO 7 PEG-7 Hydrogenated Castor Oil 0.50 Cremophor PS 20 Polysorbate 20 2.00 Dry Flo Pure Aluminum Starch Octenylsuccinate B 5.00 T-Lite SF Titanium Dioxide, Alumina Hydrate, Dimethicone / Methicone Copolymer C 4.00 1,2-propylene glycol Care Propylene Glicol 0.20 Keltrol Xanthan gum 0,50 Simulgel 600 Acrylamide / sodium acryloyldimethyltaurate copolymer, isohexadecane, polysorbate 80 Add 100 water to the. Aqua the. qs preservative 0.50 vitamin E acetate Tocopheryl acetate 2% VERB. (V) 1,00 RetiSTAR Caprylic / Capric Triglycerides, Sodium Ascorbate, Tocopherol, Retinol A 1.00 Abil Care 85 Bis-PEG / PPG-16/16 PEG / PPG-16/16 Dimethicones, Caprylic / Capric Triglycerides 3.00 Cremophor CO 40 PEG-40 Hydrogenated Castor Oil 0.30 Cremophor WO 7 PEG-7 Hydrogenated Castor Oil 2.00 Parsol 1789 Butyl methoxydibenzoylmethane 2,00 Mexoryl XL Drometrizole Trisilioxane 10.00 Witconol APM PPG-3 myristyl ether 1.00 Uvinul T 150 Ethylhexyl triazone 1.00 Dow Corning 345 Fluid Cyclopentasiloxanes, cyclohexasiloxanes 5,00 Uvinul N 539 T Octocrylene B 3.00 Z-COTE MAX Zinc Oxide (and) Diphenyl Capryl Methicone C 5.00 1,2-propylene glycol Propylene glycol 1.00 Mexoryl SX Terephthalidene Dicamphor Sulfanic Acid 0.20 Keltrol Xanthan gum 0.06 Edeta BD Disodium EDTA 0.04 TEA Triethanolamine 0.30 Carbopol Ultrez 10P Carbomer 63.50 water to the. Aqua the. 1% VERB. (V) D qs perfume oil 0.50 glydant DMDM hydantoin A 5,50 Uvinul MC 80 Ethylhexyl methoxycinnamate 2.00 Uvinul A Plus Diethylamino hydroxybenzoyl hexyl benzoate 3.00 Uvinul N 539 T Octocrylene 3.00 Emulgade PL 68/50 Cetearyl Glucoside, Cetearyl Alcohol 2.00 Dracorin 100 SE Glyceryl Stearate, PEG-100 Stearate 1.00 Fitoderm Squalane 0.50 Cremophore WO 7 PEG-7 Hydrogenated Castor Oil 0.50 Cremophor PS 20 Polysorbate 20 2.00 Dry Flo Pure Aluminum Starch Octenylsuccinate B 5.00 T-Lite SF-S Titanium Dioxide, Silica Hydrate, Alumina Hydrate, Methicone / Dimethicone Copolymer C 4.00 1,2-propylene glycol Care Propylene Glicol 0.20 Keltrol Xanthan gum 2,00 Simulgel NS Hydroxyethyl Acrylate / Sodium Acrylo yldimethyl taurate copolymer, squalane, polysorbate 60 66.30 water. Aqua the. qs preservative 0.50 vitamin E acetate Tocopheryl acetate 0.5% VERB. (V) 1,00 RetiSTAR Caprylic / Capric Triglycerides, Sodium Ascorbate, Tocopherol, Retinol A 2,00 Cremophor A 6 Ceteareth-6, stearyl alcohol 2,00 Cremophor A 25 Ceteareth-25 3.00 Syncrowax HRC Tribehenin 2,00 Lanette O Cetearyl Alcohol 2,00 Luvitol EHO Cetearyl ethylhexanoate 5.00 Uvinul MC 80 Ethylhexyl methoxycinnamate 1.00 Ganex V-220 VP / eicosene copolymer 7.00 isopropyl palmitate Isopropyl palmitate B 3.00 Z-COTE MAX Zinc Oxide (and) Diphenyl Capryl Methicone C 0.20 Keltrol Xanthan gum 0,50 Simulgel NS Hydroxyethyl acrylate / sodium acryloyl dimethyl taurate copolymer, squalane, polysorbate 60 65.10 water to the. Aqua the. 0.20 Edeta BD Disodium EDTA 5,00 1,2-propylene glycol Care Propylene glycol 0.5% VERB. (V) D 1.00 vitamin E acetate Tocopheryl acetate qs preservative A 2,00 Cremophor A 6 Ceteareth-6, stearyl alcohol 2,00 Cremophor A 25 Ceteareth-25 3.00 Syncrowax HRC Tribehenin 2,00 Lanette O Cetearyl Alcohol 2,00 Luvitol EHO Cetearyl ethylhexanoate 5.00 Uvinul MC 80 Ethylhexyl methoxycinnamate 1.00 Ganex V-220 VP / eicosene copolymer 7.00 isopropyl palmitate Isopropyl palmitate B 3.00 T-Lite SF Titanium Dioxide, Alumina Hydrate, Dimethicone / Methicone Copolymer C 0.50 Keltrol Xanthan gum 0,50 Simulgel NS Hydroxyethyl acrylate / sodium acryloyl dimethyl taurate copolymer, squalane, polysorbate 60 65.10 water to the. Aqua the. 0.20 Edeta BD Disodium EDTA 5,00 1,2-propylene glycol Care Propylene glycol 0.5% VERB. (V) D 1.00 vitamin E acetate Tocopheryl acetate qs preservative A 2,00 Cremophor A 6 Ceteareth-6, stearyl alcohol 2,00 Cremophor A 25 Ceteareth-25 3.00 Syncrowax HRC Tribehenin 2,00 Lanette O Cetearyl Alcohol 2,00 Luvitol EHO Cetearyl ethylhexanoate 5.00 Uvinul MC 80 Ethylhexyl methoxycinnamate 1.00 Ganex V-220 VP / eicosene copolymer 7.00 isopropyl palmitate Isopropyl palmitate B 3.00 T-Lite SF-S Titanium Dioxide, Silica Hydrate, Alumina Hydrate, Methicone / Dimethicone Copolymer C 0.50 Keltrol Xanthan gum 0,50 Simulgel NS Hydroxyethyl acrylate / sodium acryloyl dimethyl taurate copolymer, squalane, polysorbate 60 64.60 water. Aqua the. 0.20 Edeta BD Disodium EDTA 5,00 1,2-propylene glycol Care Propylene glycol 1% VERB. (V) D 1.00 vitamin E acetate Tocopheryl acetate qs preservative A 2,00 Cremophor A 6 Ceteareth-6, stearyl alcohol 2,00 Cremophor A 25 Ceteareth-25 3.00 Syncrowax HRC Tribehenin 2,00 Lanette O Cetearyl Alcohol 2,00 Luvitol EHO Cetearyl ethylhexanoate 5.00 Uvinul MC 80 Ethylhexyl methoxycinnamate 1.00 Ganex V-220 VP / eicosene copolymer 7.00 isopropyl palmitate Isopropyl palmitate B 3.00 T-Lite SF-S Titanium Dioxide, Silica Hydrate, Alumina Hydrate, Methicone / Dimethicone Copolymer C 0.50 Keltrol Xanthan gum 0,50 Simulgel NS Hydroxyethyl acrylate / sodium acryloyl dimethyl taurate copolymer, squalane, polysorbate 60 64.10 water. Aqua the. 2.00 Neoheliopan AP Disodium phenyl dibenzimidazole tetrasulfonates 0.20 Edeta BD Disodium EDTA 5,00 1,2-propylene glycol Care Propylene glycol D 1.00 vitamin E acetate Tocopheryl acetate 1% VERB. (V) qs preservative A 2,00 Cremophor A 6 Ceteareth-6, stearyl alcohol 2,00 Cremophor A 25 Ceteareth-25 3.00 Syncrowax HRC Tribehenin 2,00 Lanette O Cetearyl Alcohol 2,00 Luvitol EHO Cetearyl ethylhexanoate 7,00 Uvinul N 539 T Octocrylene 1.00 Ganex V-220 VP / eicosene copolymer 7.00 isopropyl palmitate Isopropyl palmitate B 3.00 T-Lite SF-S Titanium Dioxide, Silica Hydrate, Alumina Hydrate, Methicone / Dimethicone Copolymer C 0.50 Keltrol Xanthan gum 0,50 Simulgel NS Hydroxyethyl acrylate / sodium acryloyl dimethyl taurate copolymer, squalane, polysorbate 60 64.60 water. Aqua the. 1.00 Mexoryl SX Terephthalidene Dicamphor Sulfonic Acid 0.20 Edeta BD Disodium EDTA 5,00 1,2-propylene glycol Care Propylene glycol D 1.00 vitamin E acetate Tocopheryl acetate 1% VERB. (V) qs preservative A 2,00 Cremophor A 6 Ceteareth-6, stearyl alcohol 2,00 Cremophor A 25 Ceteareth-25 3.00 Syncrowax HRC Tribehenin 2,00 Lanette O Cetearyl Alcohol 2,00 Luvitol EHO Cetearyl ethylhexanoate 2,00 Mexoryl XL Drometrizole trisiloxanes 5,00 Uvinul N 539 T Octocrylene 1.00 Ganex V-220 VP / eicosene copolymer 7.00 isopropyl palmitate Isopropyl palmitate B 3.00 T-Lite SF Titanium Dioxide, Alumina Hydrate, Dimethicone / Methicone Copolymer C 0.50 Keltrol Xanthan gum 0,50 Simulgel NS Hydroxyethyl acrylate / sodium acryloyl dimethyl taurate copolymer, squalane, polysorbate 60 65.10 water to the. Aqua the. 0.20 Edeta BD Disodium EDTA 5,00 1,2-propylene glycol Care Propylene glycol D 1.00 vitamin E acetate Tocopheryl acetate 0.5% VERB. (V) qs preservative 1.00 urea urea 2.00 Neoheliopan AP Disodium phenyl dibenzimidazole tetrasulfonates 2.00 glycerin 87% glycerin 1.20 Aristoflex AVC Ammonium acryloyldimethyltaurate / VP copolymer 71.30 water. Aqua the. B 3.00 Cremophor CO 40 PEG-40 Hydrogenated Castor Oil qs perfume oil 5.00 Miglyol 812 Caprylic / Capric Triglycerides 2.00 Uvinul N 539 T Octocrylene 8.00 Z-COTE MAX Zinc Oxide (and) Diphenyl Capryl Methicone 5% VERB. (V) qs preservative 5.00 Z-COTE MAX Zinc Oxide (and) Diphenyl Capryl Methicone 2.00 Parsol 1789 Butyl methoxydibenzoylmethane 1.00 Uvinul T150 Ethylhexyl triazone 5.00 Uvinul MC 80 Ethylhexyl methoxycinnamate 2,00 Uvinul T 539 N Octocrylene 0.50 Abil 350 Dimethicone 2.75 carnic wax IT 20 Carnauba (Copernica cerifera) wax, paraffins 3.70 candelilla wax IT 281 LJ Candelilla (Euphorbia cerifera) Wax 1.80 beeswax 3050 PH Bees Wax 3.20 TeCero Wax 30445 Microcrystalline wax 3.20 TeCero wax 1030K Microcrystalline wax 1.34 Cutina CP Cetyl palmitate 6.40 Vaseline petrolatum 7,30 Softisan 100 Hydrogenated Coco-Glycerides 10.00 Luvitol EHO Cetearyl ethylhexanoate 0.17 bisabolol nat. bisabolol 1.84 vitamin E acetate Tocopheryl acetate 0.42 D, L-alpha-tocopherol tocopherol 1% VERB. (V) 40.38 castor oil Castor (Ricinus communis) Oil 5.00 T-Lite SF Titanium Dioxide, Alumina Hydrate, Dimethicone / Methicone Copolymer 2.00 Parsol 1789 Butyl methoxydibenzoylmethane 1.00 Uvinul T150 Ethylhexyl triazone 3.00 Uvinul MC 80 Ethylhexyl methoxycinnamate 2.00 Uvinul N 539 T Octocrylene 0.50 Abil 350 Dimethicone 2.75 carnic wax IT 20 Carnauba (Copernica cerifera) wax, paraffin 3.70 candelilla wax IT 281 LJ Candelilla (Euphorbia cerifera) Wax 1.80 beeswax 3050 PH Bees Wax 3.20 TeCero Wax 30445 Microcrystalline wax 3.20 TeCero wax 1030K Microcrystalline wax 1.34 Cutina CP Cetyl palmitate 6.40 Vaseline petrolatum 7,30 Softisan 100 Hydrogenated Coco-Glycerides 10.00 Luvitol EHO Cetearyl ethylhexanoate 0.17 bisabolol nat. bisabolol 1.84 vitamin E acetate Tocopheryl acetate 0.42 D, L-alpha-tocopherol tocopherol 1% VERB. (V) 40.38 castor oil Castor (Ricinus communis) Oil 5.00 T-Lite SF-S Titanium Dioxide, Silica Hydrate, Alumina Hydrate, Methicone / Dimethicone Copolymer 2.00 Uvinul A Plus Diethylamino hydroxybenzoyl hexyl benzoate 2,00 Mexoryl XL Drometrizole trisiloxanes 3.00 Uvinul MC 80 Ethylhexyl methoxycinnamate 0.50 Abil 350 Dimethicone 2.75 Carnic wax LT 20 Carnauba (Copernica cerifera) wax, paraffins 3.70 Candelilla Wax LT 281 LJ Candelilla (Euphorbia cerifera) Wax 1.80 beeswax 3050 PH Bees Wax 3.20 TeCero Wax 30445 Microcrystalline wax 3.20 TeCero wax 1030K Microcrystalline wax 1.34 Cutina OP Cetyl palmitate 6.40 Vaseline petrolatum 7,30 Softisan 100 Hydrogenated Coco-Glycerides 10.00 Luvitol EHO Cetearyl ethylhexanoate 0.17 bisabolol nat. bisabolol 1.84 vitamin E acetate Tocopheryl acetate 0.42 D, L-alpha-tocopherol tocopherol 2% VERB. (V) 39.38 castor oil Castor (Ricinus communis) Oil A 6,00 Cremophor WO 7 PEG-7 Hydrogenated Castor Oil 2,00 Elfacos ST 9 PEG-45 / dodecyl glycol copolymer 3.00 isopropyl myristate Isopropyl myristate 8,00 jojoba oil Simmondsia chinensis (Jojoba) Seed Oil 4.00 Uvinul MC 80 Ethylhexyl methoxycinnamate 2.00 Uvinul A Plus Diethylamino Hydroxybenzoyl Hexyl Benzoate 1.00 Abil 350 Dimethicone B 5.00 Z-COTE MAX Zinc Oxide (and) Diphenyl Capryl Methicone 3.00 T-Lite SF Titanium Dioxide, Alumina Hydrate, Dimethicone / Methicone Copolymer C 0.20 Edeta BD Disodium EDTA 5.00 Glycerin 87% glycerin 0.30 Chemag 2000 Imidazolidinyl urea 59.00 water to the. Aqua the. D qs perfume oil 1% VERB. (V) qs preservative 2,00 Cremophor A 6 Ceteareth-6, stearyl alcohol 2,00 Cremophor A 25 Ceteareth-25 3.00 Syncrowax HRC Tribehenin 2,00 Lanette O Cetearyl Alcohol 2,00 Luvitol EHO Cetearyl ethylhexanoate 5.00 Uvinul MC 80 Ethylhexyl methoxycinnamate 1.00 Uvinul T 150 Ethylhexyl triazone 1.00 Ganex V-220 VP / eicosene copolymer 7.00 isopropyl myristate Isopropyl myristate B 5.00 Z-COTE MAX Zinc Oxide (and) Diphenyl Capryl Methicone C 0.20 Keltrol Xanthan gum 0,50 Simulgel NS Hydroxyethyl acrylate / sodium acryloyl dimethyl taurate copolymer, squalane, polysorbate 60 61.10 water to the. Aqua the. 0.20 Edeta BD Disodium EDTA 5,00 1,2-propylene glycol Care Propylene glycol D 1.00 vitamin E acetate Tocopheryl acetate 1.5% VERB. (V) qs preservative A 2,00 Luvitol EHO Cetearyl ethylhexanoate 5.00 paraffin oil Mineral oil 5.00 Z-COTE MAX Zinc Oxide (and) Diphenyl Capryl Methicone B 1.00 Cremophor A 6 Ceteareth-6, stearyl alcohol 2,00 Cremophor A 25 Ceteareth-25 3.00 glycerol monostearate Glyceryl stearate 4.00 cetylstearyl alcohol Cetearyl Alcohol C 5,00 1,2-propylene glycol Care Propylene glycol 7.50 Luviquat Care Polyquaternium-44 qs preservative qs perfume oil 1% VERB. (V) 64.50 water to the. Aqua the. 5.00 T-Lite SF Titanium Dioxide, Alumina Hydrate, Dimethicone / Methicone Copolymer 10.00 Z-COTE MAX Zinc Oxide (and) Diphenyl Capryl Methicone 12,00 Beeswax 3044 PH Bees Wax 8.00 candelilla wax IT 281 LJ Candelilla (Euphorbia cerifera) Wax 5.00 Tegin Glyceryl Stearate SE 5.00 Dow Corning 345 Fluid Cyclopentasiloxanes, cyclohexasiloxanes 5.00 Witconol APM PPG-3 myristyl ether 5.00 Softisan 154 Hydrogenated Palm Oil 8,00 paraffin oil, viscous Mineral oil 3.00 Vaseline petrolatum 2% VERB. (V) 32.00 castor oil Castor (Ricinus communis) Oil 3.00 Uvinul MC 80 Ethylhexyl methoxycinnamate 2.00 Uvinul T 150 Ethylhexyl triazone 2.00 Uvinul A Plus Diethylamino hydroxybenzoyl hexyl benzoate 10.00 Z-COTE MAX Zinc Oxide (and) Diphenyl Capryl Methicone 12,00 Beeswax 3044 PH Bees Wax 3.00 Vaseline petrolatum 8.00 candelilla wax IT 281 LJ Candelilla (Euphorbia cerifera) Wax 8,00 paraffin oil, viscous Mineral oil 5.00 Tegin Glyceryl Stearate SE 5.00 Softisan 154 Hydrogenated Palm Oil 5.00 Witconol APM PPG-3 myristyl ether 5.00 Dow Corning 345 Fluid Cyclopentasiloxanes, cyclohexasiloxanes 0.1% VERB. (V) 28.90 castor oil Castor (Ricinus communis) Oil 5.00 T-Lite SF Titanium Dioxide, Alumina Hydrate, Dimethicone / Methicone Copolymer 6.00 Finsolv TN C12-15 alkyl benzoates 10,00 Uvinul MC 80 Ethylhexyl methoxycinnamate 6.00 Miglyol 812 Caprylic / Capric Triglycerides 5.00 Arlacel P 135 PEG-30 dipolyhydroxystearates 2.00 Ganex V 216 PVP / hexadecenes copolymer 2,00 Elfacos ST 9 PEG-45 / dodecyl glycol copolymer B 3,00 1,2-propylene glycol Care Propylene glycol 0.10 Edeta BD Disodium EDTA 1.00 magnesium sulfate 7-hydrate Magnesium sulphates 59.40 water to the. Aqua the. 0.5% VERB. (V) qs preservative A 4,00 Dehymuls SBL Polyglyceryl-2 Dipolyhydroxystearates, Dicaprylyl Ethers, Cocoglycerides, Sorbitan Sesquioleate, Cera Alba, Aluminum Stearates, Dicocoyl Pentaerythrityl Distearyl Citrate 1.00 Dehymuls PGPH Polyglyceryl-2 dipolyhydroxystearates 8.00 Finsolv TN C12-15 alkyl benzoates 4.00 Miglyol 812 Caprylic / Capric Triglycerides 4.00 Uvinul MC 80 Ethylhexyl methoxycinnamate 2.00 Uvinul N 539 T Octocrylene B 5.00 Z-COTE MAX Zinc Oxide (and) Diphenyl Capryl Methicone C 3.00 1,2-propylene glycol Care Propylene glycol 0.30 Abiol Imidazolidinyl urea 1.00 magnesium sulfate 7-hydrate Magnesium sulphates Ad 100 water to the. Aqua the. 1.5% VERB. (V) D qs preservative A 4,00 Dehymuls SBL Polyglyceryl-2 Dipolyhydroxystearates, Dicaprylyl Ethers, Cocoglycerides, Sorbitan Sesquioleate, Cera Alba, Aluminum Stearates, Dicocoyl Pentaerythrityl Distearyl Citrate 1.00 Dehymuls PGPH Polyglyceryl-2 dipolyhydroxystearates 8.00 Finsolv TN C12-15 alkyl benzoates 4.00 Miglyol 812 Caprylic / Capric Triglycerides 4.00 Uvinul MC 80 Ethylhexyl methoxycinnamate 2.00 Uvinul N 539 T Octocrylene B 5.00 T-Lite SF-S Titanium Dioxide, Silica Hydrate, Alumina Hydrate, Methicone / Dimethicone Copolymer C 3.00 1,2-propylene glycol Care Propylene glycol 0.30 Abiol Imidazolidinyl urea 1,00Magnesiumsulfat 7-hydrate Magnesium sulphates 1.0% VERB. (V) Ad 100 water to the. Aqua the. D qs preservative A 4,00 Dehymuls SBL Polyglyceryl-2 Dipolyhydroxystearates, Dicaprylyl Ethers, Cocoglycerides, Sorbitan Sesquioleate, Cera Alba, Aluminum Stearates, Dicocoyl Pentaerythrityl Distearyl Citrate 1.00 Dehymuls PGPH Polyglyceryl-2 dipolyhydroxystearates 8.00 Finsolv TN C12-15 alkyl benzoates 4.00 Miglyol 812 Caprylic / Capric Triglycerides 8,00 Uvinul A Plus B Ethylhexyl methoxycinnamate and diethylamino hydroxybenzoyl hexyl benzoate 2.00 Uvinul N 539 T Octocrylene B 5.00 Z-COTE MAX Zinc Oxide (and) Diphenyl Capryl Methicone C 3.00 1,2-propylene glycol Care Propylene glycol 0.30 Abiol Imidazolidinyl urea 1.00 magnesium sulfate 7-hydrate Magnesium sulphates 0.1% VERB. (V) Ad 100 water to the. Aqua the. qs preservative A 4,00 Dehymuls SBL Polyglyceryl-2 Dipolyhydroxystearates, Dicaprylyl Ethers, Cocoglycerides, Sorbitan Sesquioleate, Cera Alba, Aluminum Stearates, Dicocoyl Pentaerythrityl Distearyl Citrate 1.00 Dehymuls PGPH Polyglyceryl-2 dipolyhydroxystearates 8.00 Finsolv TN C12-15 alkyl benzoates 4.00 Miglyol 812 Caprylic / Capric Triglycerides 8,00 Uvinul A Plus B Ethylhexyl methoxycinnamate and diethylamino hydroxybenzoyl hexyl benzoate 2.00 Uvinul N 539 T Octocrylene B 5.00 T-Lite SF Titanium Dioxide, Alumina Hydrate, Dimethicone / Methicone Copolymer C 3.00 1,2-propylene glycol Care Propylene glycol 0.30 Abiol Imidazolidinyl urea 1.00 magnesium sulfate 7-hydrate Magnesium sulphates Ad 100 water to the. Aqua the. 0.2% VERB. (V) qs preservative A 4,00 Dehymuls SBL Polyglyceryl-2 Dipolyhydroxystearates, Dicaprylyl Ethers, Cocoglycerides, Sorbitan Sesquioleate, Cera Alba, Aluminum Stearates, Dicocoyl Pentaerythrityl Distearyl Citrate 1.00 Dehymuls PGPH Polyglyceryl-2 dipolyhydroxystearates 8.00 Finsolv TN C12-15 alkyl benzoates 4.00 Miglyol 812 Caprylic / Capric Triglycerides 8,00 Uvinul A Plus B Ethylhexyl methoxycinnamate and diethylamino hydroxybenzoyl hexyl benzoate 2.00 Uvinul N 539 T Octocrylene B 5.00 T-Lite SF-S Titanium Dioxide, Silica Hydrate, Alumina Hydrate, Methicone / Dimethicone Copolymer C 3.00 1,2-propylene glycol Care Propylene glycol 0.30 Abiol Imidazolidinyl urea 1.00 magnesium sulfate 7-hydrate Magnesium sulphates 0.5% VERB. (V) Ad 100 water to the. Aqua the. qs preservative A 4,00 Dehymuls SBL Polyglyceryl-2 Dipolyhydroxystearates, Dicaprylyl Ethers, Cocoglycerides, Sorbitan Sesquioleate, Cera Alba, Aluminum Stearates, Dicocoyl Pentaerythrityl Distearyl Citrate 1.00 Dehymuls PGPH Polyglyceryl-2 dipolyhydroxystearates 8.00 Finsolv TN C12-15 alkyl benzoates 4.00 Miglyol 812 Caprylic / Capric Triglycerides 7,00 Uvinul MC 80 Ethylhexyl methoxycinnamate 2,00 Mexoryl XL Drometrizole trisiloxanes B 5.00 Z-COTE MAX Titanium Dioxide, Alumina Hydrate, Dimethicone / Methicone Copolymer C 3.00 1,2-propylene glycol Care Propylene glycol 0.30 Abiol Imidazolidinyl urea 1.00 magnesium sulfate 7-hydrate Magnesium sulphates Ad 100 water to the. Aqua the. 0.01% VERB. (V) qs preservative A 7.50 Uvinul MC 80 Ethylhexyl methoxycinnamate 3.00 Uvinul N 539 T Octocrylene 2.00 Uvinul A Plus Diethylamino hydroxybenzoyl hexyl benzoate 1.00 Cremophor CO 40 PEG-40 Hydrogenated Castor Oil 10.00 Miglyol 812 Caprylic / Capric Triglycerides 1.50 Dow Corning 345 fluid Cyclopentasiloxanes, cyclohexasiloxanes B 3,50 Luvigel EM Caprylic / Capric Triglyceride, Sodium Acrylate Copolymer C 46.00 water to the. Aqua the. D 5.00 1,2-propylene glycol Care Propylene glycol 0.50 Cremophore A 25 Ceteareth-25 0.05% VERB. (V) 20.00 ethanol 96% Alcohol A 1.00 Uvinul A Plus Diethylamino hydroxybenzoyl hexyl benzoate 1,00 Tinosorb S Bis-Ethylhexyloxyphenol Methoxyphenyl Triazines 3.00 Uvinul MC 80 Ethylhexyl methoxycinnamate 8,00 Miglyol 812 Caprylic / Capric Triglycerides 1.50 Dow Corning 350 Fluid Dimethicone 3.00 Z-COTE MAX Titanium Dioxide, Alumina Hydrate, Dimethicone / Methicone Copolymer 3.00 Finsolv TN C12-15 alkyl benzoates 1.00 Cremophor CO 40 PEG-40 Hydrogenated Castor Oil B 2.00 Luvigel EM Caprylic / Capric Triglyceride, Sodium Acrylate Copolymer C 54,80 water the. Aqua the. D 15.00 Ethanol 96% Alcohol 5,00 1,2-propylene glycol Care Propylene glycol 0.50 Cremophore A 25 Ceteareth-25 1.0% VERB. (V) 1.00 vitamin E acetate Tocopheryl acetate 0.20 bisabolol rac. bisabolol A 4,00 Dehymuls SBL Polyglyceryl-2 Dipolyhydroxystearates, Dicaprylyl Ethers, Cocoglycerides, Sorbitan Sesquioleate, Cera Alba, Aluminum Stearates, Dicocoyl Pentaerythrityl Distearyl Citrate 1.00 Dehymuls PGPH Polyglyceryl-2 dipolyhydroxystearates 6.00 Finsolv TN C12-15 alkyl benzoates 6.00 Miglyol 812 Caprylic / Capric Triglycerides 5.00 Uvinul MC 80 Ethylhexyl methoxycinnamate 3.00 Neoheliopan HMS Homosalate B 5.00 Z-COTE MAX Zinc Oxide (and) Diphenyl Capryl Methicone C 3.00 1,2-propylene glycol Care Propylene glycol 0.30 Chemag 2000 Imidazolidinyl urea 1.00 magnesium sulfate 7-hydrate Magnesium sulphates 65.10 water to the. Aqua the. 0.1% VERB. (V) qs preservative A 4.00 Tego Care 450 Polyglyceryl-3 Methyl Glucose Distearate 4.50 Uvinul MC 80 Ethylhexyl methoxycinnamate 3.00 Uvinul N 539 T Octocrylene 2.00 Uvinul T 150 Ethylhexyl triazone 0.50 vitamin E acetate Tocopheryl acetate B 5.00 isohexadecane Isohexadecane 5.00 Cosmacol EMI Di-C12-13 alkyl malate 3.50 Cetiol SN Cetearyl Isononanoate 1.00 Ganex V-220 VP / eicosene copolymer 5.00 T-Lite SF Titanium Dioxide, Alumina Hydrate, Dimethicone / Methicone Copolymer C 60,00 water the. Water 5.00 Glycerin 87% glycerin 1,00 Lanette E Sodium Cetearyl Sulfate 0.30 Keltrol Xanthan gum 0.2% VERB. (V) D qs preservative A 4.00 Tego Care 450 Polyglyceryl-3 Methyl Glucose Distearate 4.50 Uvinul MC 80 Ethylhexyl methoxycinnamate 3.00 Uvinul N 539 T Octocrylene 2.00 Neoheliopan HMS Homosalate 0.50 vitamin E acetate Tocopheryl acetate B 5.00 isohexadecane Isohexadecane 5.00 Cosmacol EMI Di-C12-13 alkyl malate 3.50 Cetiol SN Cetearyl Isononanoate 1.00 Ganex V-220 VP / eicosene copolymer 5.00 T-Lite SF Titanium Dioxide, Alumina Hydrate, Dimethicone / Methicone Copolymer C 59.20 water to the. Aqua the. 5.00 Glycerin 87% glycerin 1,00 Lanette E Sodium Cetearyl Sulfate 0.30 Keltrol Xanthan gum 1.0% VERB. (V) D qs preservative A 4.00 Tego Care 450 Polyglyceryl-3 Methyl Glucose Distearate 4.50 Uvinul MC 80 Ethylhexyl methoxycinnamate 3.00 Neoheliopan OS Octisalate 2.00 Neoheliopan HMS Homosalate 0.50 vitamin E acetate Tocopheryl acetate B 5.00 isohexadecane Isohexadecane 5.00 Cosmacol EMI Di-C12-13 alkyl malate 3.50 Cetiol SN Cetearyl Isononanoate 1.00 Ganex V-220 VP / eicosene copolymer 5.00 Z-COTE MAX Zinc Oxide (and) Diphenyl Capryl Methicone C 60,15 water the. Aqua the 5.00 Glycerin 87% glycerin 1,00 Lanette E Sodium Cetearyl Sulfate 0.30 Keltrol Xanthan gum 0.05% VERB. (V) D qs preservative A 4.00 Tego Care 450 Polyglyceryl-3 Methyl Glucose Distearate 4,50 Uvinul N 539 T Octocrylene 3.00 Neoheliopan OS Octisalate 2.00 Neoheliopan HMS Homosalate 0.50 vitamin E acetate Tocopheryl acetate B 5.00 isohexadecane Isohexadecane 5.00 Cosmacol EMI Di-C12-13 alkyl malate 3.50 Cetiol SN Cetearyl Isononanoate 1.00 Ganex V-220 VP / eicosene copolymer 5.00 Z-COTE MAX Zinc Oxide (and) Diphenyl Capryl Methicone C 60,19 water the. Aqua the. 5.00 Glycerin 87% glycerin 1,00 Lanette E Sodium Cetearyl Sulfate 0.30 Keltrol Xanthan gum 0.01% VERB. (V) D qs preservative A 4.00 Tego Care 450 Polyglyceryl-3 Methyl Glucose Distearate 4,50 Uvinul N 539 T Octocrylene 3.00 Neoheliopan OS Octisalate 2.00 Neoheliopan HMS Homosalate 0.50 vitamin E acetate Tocopheryl acetate B 5.00 isohexadecane Isohexadecane 5.00 Cosmacol EMI Di-C12-13 alkyl malate 3.50 Cetiol SN Cetearyl Isononanoate 1.00 Ganex V-220 VP / eicosene copolymer 5.00 T-Lite SF-S Titanium Dioxide, Silica Hydrate, Alumina Hydrate, Methicone / Dimethicone Copolymer C 59.20 water to the. Aqua the. 5.00 Glycerin 87% glycerin 1,00 Lanette E Sodium Cetearyl Sulfate 0.30 Keltrol Xanthan gum 1.0% VERB. (V) D qs preservative A 8,00 Cetiol B Dibutyl adipate 8.00 Finsolv TN C12-15 alkyl benzoates 12.00 Myritol 331 Cocoglycerides 1,00 Lanette E Sodium Cetearyl Sulfate 4.00 Eumulgin VL 75 Lauryl glucoside, polyglyceryl-2 dipolyhydroxystearates, glycerin 2,00 Lanette O Cetearyl Alcohol 3.00 Tinosorb S Bis-Ethylhexyloxyphenol Methoxyphenyl Triazines 1.00 vitamin E acetate Tocopheryl acetate B 4.00 Z-COTE MAX Zinc Oxide (and) Diphenyl Capryl Methicone C 3.00 Glycerine 87% glycerin 0.05 Edeta BD Disodium EDTA 0.20 allantoin allantoin 0.30 Keltrol Xanthan gum 1.50 Veegum Ultra Magnesium Aluminum Silicate 49.45 water. Aqua the. 1.0% VERB. (V) D qs preservative A 8,00 Cetiol B Dibutyl adipate 8.00 Finsolv TN C12-15 alkyl benzoates 12.00 Myritol 331 Cocoglycerides 1,00 Lanette E Sodium Cetearyl Sulfate 4.00 Eumulgin VL 75 Lauryl glucoside, polyglyceryl-2 dipolyhydroxystearates, glycerin 2,00 Lanette O Cetearyl Alcohol 3.00 Tinosorb S Bis-Ethylhexyloxyphenol Methoxyphenyl Triazines 1.00 vitamin E acetate Tocopheryl acetate B 4.00 T-Lite SF Titanium Dioxide, Alumina Hydrate, Dimethicone / Methicone Copolymer C 3.00 Glycerin 87% glycerin 0.05 Edeta BD Disodium EDTA 0.20 allantoin allantoin 0.30 Keltrol Xanthan gum 1.50 Veegum Ultra Magnesium Aluminum Silicate 50.25 water. Aqua the. D 0.50 citric acid Citric Acid qs perfume oil 0.2% VERB. (V) qs preservative A 5.00 Cosmacol EMI Di-C12-13 alkyl malate 4.50 Uvinul MC 80 Ethylhexyl methoxycinnamate 3.00 Uvinul N 539 T Octocrylene 2.00 Uvinul T 150 Ethylhexyl triazone B 4.00 Tego Care 450 Polyglyceryl-3 Methyl Glucose Distearate 5.00 isohexadecane Isohexadecane 3.50 Cetiol SN Cetearyl Isononanoate 0.50 vitamin E acetate Tocopheryl acetate 1.00 Ganex V-220 VP / eicosene copolymer 2.50 T-Lite SF Titanium Dioxide, Alumina Hydrate, Dimethicone / Methicone Copolymer C 5.00 Glycerin 87% glycerin 2,00 Lanette E Sodium Cetearyl Sulfate 0.30 Keltrol Xanthan gum 1.00 Pationic 138 C Sodium Lauroyl Lactylate 1.00 Pationic SSL Sodium stearoyl lactylate 42.00 water to the. Aqua the D 5.00 Eusolex 232 Phenylbenzimidazole sulfonic acid 10.00 water to the. Aqua the E 0.70 sodium hydroxide Sodium hydroxides 1.0% VERB. (V) qs preservative A 5.00 Cosmacol EMI Di-C12-13 alkyl malate 4.50 Uvinul MC 80 Ethylhexyl methoxycinnamate 3.00 Uvinul N 539 T Octocrylene 2.00 Uvinul A Plus Diethylamino Hydrobenzoyl Hexyl Benzoate B 4.00 Tego Care 450 Polyglyceryl-3 Methyl Glucose Distearate 5.00 isohexadecane Isohexadecane 3.50 Cetiol SN Cetearyl Isononanoate 0.50 vitamin E acetate Tocopheryl acetate 1.00 Ganex V-220 VP / eicosene copolymer 2.50 T-Lite SF Titanium Dioxide, Alumina Hydrate, Dimethicone / Methicone Copolymer C 5.00 Glycerin 87% glycerin 2,00 Lanette E Sodium Cetearyl Sulfate 0.30 Keltrol Xanthan gum 1.00 Pationic 138 C Sodium Lauroyl Lactylate 1.00 Pationic SSL Sodium stearoyl lactylate 41.00 water. Aqua the D 5.00 Eusolex 232 Phenylbenzimidazole sulfonic acid 2.0% VERB. (V) 10.00 water to the. Aqua the E 0.70 sodium hydroxide Sodium hydroxides qs preservative A 5.00 Cosmacol EMI Di-C12-13 alkyl malate 4.50 Uvinul MC 80 Ethylhexyl methoxycinnamate 3.00 Uvinul N 539 T Octocrylene 2.00 Uvinul A Plus Diethylamino Hydrobenzoyl Hexyl Benzoate B 4.00 Tego Care 450 Polyglyceryl-3 Methyl Glucose Distearate 5.00 isohexadecane Isohexadecane 3.50 Cetiol SN Cetearyl Isononanoate 0.50 vitamin E acetate Tocopheryl acetate 1.00 Ganex V-220 VP / eicosene copolymer 2.50 Z-COTE MAX Zinc Oxide A (nd) Diphenyl Capryl Methicone C 5.00 Glycerin 87% glycerin 2,00 Lanette E Sodium Cetearyl Sulfate 0.30 Keltrol Xanthan gum 1.00 Pationic 138 C Sodium Lauroyl Lactylate 1.00 Pationic SSL Sodium stearoyl lactylate 42.50 water to the. Aqua the D 5.00 Eusolex 232 Phenylbenzimidazole sulfonic acid 0.5% VERB. (V) 10.00 water to the. Aqua the E 0.70 sodium hydroxide Sodium hydroxides qs preservative A 5.00 Cosmacol EMI Di-C12-13 alkyl malate 7,50 Uvinul N 539 T Octocrylene 2,00 Mexoryl XL Drometrizole trisiloxanes B 4.00 Tego Care 450 Polyglyceryl-3 Methyl Glucose Distearate 5.00 isohexadecane Isohexadecane 3.50 Cetiol SN Cetearyl Isononanoate 0.50 vitamin E acetate Tocopheryl acetate 1.00 Ganex V-220 VP / eicosene copolymer 5.00 Z-COTE MAX Zinc Oxide A (nd) Diphenyl Capryl Methicone C 5.00 Glycerin 87% glycerin 2,00 Lanette E Sodium Cetearyl Sulfate 0.30 Keltrol Xanthan gum 1.00 Pationic 138 C Sodium Lauroyl Lactylate 1.00 Pationic SSL Sodium stearoyl lactylate 40,50 water. Aqua the D 5.00 Eusolex 232 Phenylbenzimidazole sulfonic acid 1.0% VERB. (V) 10.00 water to the. Aqua the E 0.70 sodium hydroxide Sodium hydroxides qs preservative A 5.00 Cosmacol EMI Di-C12-13 alkyl malate 5,50 Uvinul N 539 T Octocrylene 2.00 Uvinul A Plus Diethylamino Hydrobenzoyl Hexyl Benzoate 2,00 Mexoryl XL Drometrizole trisiloxanes B 4.00 Tego Care 450 Polyglyceryl-3 Methyl Glucose Distearate 5.00 isohexadecane Isohexadecane 3.50 Cetiol SN Cetearyl Isononanoate 0.50 vitamin E acetate Tocopheryl acetate 1.00 Ganex V-220 VP / eicosene copolymer 5.00 Z-COTE MAX Zinc Oxide A (nd) Diphenyl Capryl Methicone C 5.00 Glycerin 87% glycerin 2,00 Lanette E Sodium Cetearyl Sulfate 0.30 Keltrol Xanthan gum 1.00 Pationic 138 C Sodium Lauroyl Lactylate 1.00 Pationic SSL Sodium stearoyl lactylate 41.50 water to the. Aqua the D 5.00 Eusolex 232 Phenylbenzimidazole sulfonic acid 0.5% VERB. (V) 9.50 water to the. Aqua the E 0.70 sodium hydroxide Sodium hydroxides qs preservative A 5.00 Cosmacol EMI Di-C12-13 alkyl malate 5,50 Uvinul N 539 T Octocrylene 2.00 Uvinul A Plus Diethylamino Hydrobenzoyl Hexyl Benzoate 2,00 Mexoryl XL Drometrizole trisiloxanes B 4.00 Tego Care 450 Polyglyceryl-3 Methyl Glucose Distearate 5.00 isohexadecane Isohexadecane 3.50 Cetiol SN Cetearyl Isononanoate 0.50 vitamin E acetate Tocopheryl acetate 1.00 Ganex V-220 VP / eicosene copolymer 5.00 T-Lite SF-S Titanium Dioxide, Silica Hydrate, Alumina Hydrate, Methicone / Dimethicone Copolymer C 5.00 Glycerin 87% glycerin 2,00 Lanette E Sodium Cetearyl Sulfate 0.30 Keltrol Xanthan gum 1.00 Pationic 138 C Sodium Lauroyl Lactylate 1.00 Pationic SSL Sodium stearoyl lactylate 40,50 water. Aqua the D 5.00 Eusolex 232 Phenylbenzimidazole sulfonic acid 1.0% VERB. (V) 10.00 water to the. Aqua the E 0.70 sodium hydroxide Sodium hydroxides qs preservative A 8,00 Cetiol B Dibutyl adipate 8.00 Finsolv TN C12-15 alkyl benzoates 10.00 Myritol 331 Cocoglycerides 1,00 Lanette E Sodium Cetearyl Sulfate 4.00 Eumulgin VL 75 Lauryl glucoside, polyglyceryl-2 dipolyhydroxystearates, glycerin 2,00 Lanette O Cetearyl Alcohol 1,00 Tinosorb S Bis-Ethylhexyloxyphenol Methoxyphenyl Triazines 1.00 Uvinul T 150 Ethylhexyl triazone 1.00 vitamin E acetate Tocopheryl acetate B 5.00 T-Lite SF Titanium Dioxide, Alumina Hydrate, Dimethicone / Methicone Copolymer C 3.00 Glycerin 87% glycerin 0.05 Edeta BD Disodium EDTA 0.20 allantoin allantoin 0.30 Keltrol Xanthan gum 2.0% VERB. (V) 1.50 Veegum Ultra Magnesium Aluminum Silicate Add 100 water to the. Aqua the D qs perfume oil qs preservative A 8,00 Cetiol B Dibutyl adipate 8.00 Finsolv TN C12-15 alkyl benzoates 10.00 Myritol 331 Cocoglycerides 1,00 Lanette E Sodium Cetearyl Sulfate 4.00 Eumulgin VL 75 Lauryl glucoside, polyglyceryl-2 dipolyhydroxystearates, glycerin 2,00 Lanette O Cetearyl Alcohol 1,00 Tinosorb S Bis-ethylhexyloxyphenol Methoxyphenyl triazines 1.00 Uvinul T 150 Ethylhexyl triazone 1.00 vitamin E acetate Tocopheryl acetate B 5.00 Z-COTE MAX Zinc Oxide (and) Diphenyl Capryl Methicone C 3.00 Glycerin 87% glycerin 0.05 Edeta BD Disodium EDTA 0.20 allantoin allantoin 0.30 Keltrol Xanthan gum 1.0% VERB. (V) 1.50 Veegum Ultra Magnesium Aluminum Silicate Add 100 water to the. Aqua the D qs perfume oil qs preservative A 3.00 Glycerin 87% glycerin 0.20 Edeta BD Disodium EDTA 0.30 Abiol Imidazolidinyl urea 1.00 Plantacare 2000 Decyl glucosides 0.30 Keltrol T Xanthan gum 57.00 water. Aqua the. B 5.00 T-Lite SF-S Titanium Dioxide, Silica Hydrate, Alumina Hydrate, Methico-ne / Dimethicone Copolymer C 7.50 Uvinul MC 80 Ethylhexyl methoxycinnamate 2.00 Uvinul A Plus Diethylamino hydroxybenzoyl hexyl benzoate 2.00 Dow Corning 345 Fluid Cyclopentasiloxanes, cyclohexasiloxanes 3.50 Cremophor A 6 Ceteareth-6, stearyl alcohol 1.50 Cremophor A 25 Ceteareth-25 0.50 beeswax 3044 PH Bees Wax 3.00 Lanette O Cetearyl Alcohol 10.00 Miglyol 812 Caprylic / Capric Triglycerides D 1.00 vitamin E acetate Tocopheryl acetate 2.0% VERB. (V) 0.20 bisabolol rac. bisabolol A 3.00 Glycerin 87% glycerin 0.20 Edeta BD Disodium EDTA 0.30 Abiol Imidazolidinyl urea 1.00 Plantacare 2000 Decyl glucosides 0.30 Keltrol T Xanthan gum 58.00 water to the. Aqua the. B 5.00 Z-COTE MAX Zinc Oxide (and) Diphenyl Capryl Methicone C 7.50 Uvinul MC 80 Ethylhexyl methoxycinnamate 2.00 Uvinul A Plus Diethylamino hydroxybenzoyl hexyl benzoate 2.00 Dow Corning 345 Fluid Cyclopentasiloxanes, cyclohexasiloxanes 3.50 Cremophor A 6 Ceteareth-6, stearyl alcohol 1.50 Cremophor A 25 Ceteareth-25 0.50 beeswax 3044 PH Bees Wax 3.00 Lanette O Cetearyl Alcohol 10.00 Miglyol 812 Caprylic / Capric Triglycerides D 1.00 vitamin E acetate Tocopheryl acetate 1.0% VERB. (V) bisabolol 0.20 bisabolol rac. A 3.00 Glycerin 87% glycerin 0.20 Edeta BD Disodium EDTA 0.30 Abiol Imidazolidinyl urea 1.00 Plantacare 2000 Decyl glucosides 0.30 Keltrol T Xanthan gum 58.50 water to the. Aqua the. B 5.00 T-Lite SF-S Titanium Dioxide, Silica Hydrate, Alumina Hydrate, Methicone / Dimethicone Copolymer C 7.50 Uvinul MC 80 Ethylhexyl methoxycinnamate 5,00 Uvinul N 539 T Octocrylene 2.00 Parsol 1789 Butyl methoxydibenzoylmethane 2.00 Dow Corning 345 Fluid Cyclopentasiloxanes, cyclohexasiloxanes 3.50 Cremophor A 6 Ceteareth-6, stearyl alcohol 1.50 Cremophor A 25 Ceteareth-25 0.50 beeswax 3044 PH Bees Wax 3.00 Lanette O Cetearyl Alcohol 10.00 Miglyol 812 Caprylic / Capric Triglycerides D 1.00 vitamin E acetate Tocopheryl acetate 0.5% VERB. (V) 0.20 bisabolol rac. bisabolol A 3.00 Glycerin 87% glycerin 0.20 Edeta BD Disodium EDTA 0.30 Abiol Imidazolidinyl urea 1.00 Plantacare 2000 Decyl glucosides 0.30 Keltrol T Xanthan gum 2,00 Mexoryl SL Terephthalidene Dicamphor Sulfonic Acid 58.40 water. Aqua the. B 6.00 T-Lite SF-S Titanium Dioxide, Silica Hydrate, Alumina Hydrate, Methicone / Dimethicone Copolymer 6.00 Uvinul N 539 T Octocrylene 2.00 Parsol 1789 Butyl methoxydibenzoylmethane 2.00 Dow Corning 345 Fluid Cyclopentasiloxanes, cyclohexasiloxanes 3.50 Cremophor A 6 Ceteareth-6, stearyl alcohol 1.50 Cremophor A 25 Ceteareth-25 0.50 beeswax 3044 PH Bees Wax 3.00 Lanette O Cetearyl Alcohol 10.00 Miglyol 812 Caprylic / Capric Triglycerides D 1.00 vitamin E acetate Tocopheryl acetate 0.1% VERB. (V) 0.20 bisabolol rac. bisabolol A 3.00 Glycerin 87% glycerin 0.20 Edeta BD Disodium EDTA 0.30 Abiol Imidazolidinyl urea 1.00 Plantacare 2000 Decyl glucosides 0.30 Keltrol T Xanthan gum 2,00 Mexoryl SL Terephthalid Dicamphor Sulfonic Acid 58.45 water to the. Aqua the. B 6.00 Z-COTE MAX Zinc Oxide (and) Diphenyl Capryl Methicone 6.00 Uvinul N 539 T Octocrylene 2.00 Parsol 1789 Butyl methoxydibenzoylmethane 2.00 Dow Corning 345 Fluid Cyclopentasiloxanes, cyclohexasiloxanes 3.50 Cremophor A 6 Ceteareth-6, stearyl alcohol 1.50 Cremophor A 25 Ceteareth-25 0.50 beeswax 3044 PH Bees Wax 3.00 Lanette O Cetearyl Alcohol 10.00 Miglyol 812 Caprylic / Capric Triglycerides D 1.00 vitamin E acetate Tocopheryl acetate 0.05% VERB. (V) 0.20 bisabolol rac. bisabolol A 3.00 Glycerin 87% glycerin 0.20 Edeta BD Disodium EDTA 0.30 Abiol Imidazolidinyl urea 1.00 Plantacare 2000 Decyl glucosides 0.30 Keltrol T Xanthan gum 2.00 Neoheliopan AP Disodium phenyl dibenzimidazole tetrasulfonates 57.50 water to the. Aqua the. B 6.00 Z-COTE MAX Zinc Oxide (and) Diphenyl Capryl Methicone 6.00 Uvinul N 539 T Octocrylene 2.00 Parsol 1789 Butyl methoxydibenzoylmethane 2.00 Dow Corning 345 Fluid Cyclopentasiloxanes, cyclohexasiloxanes 3.50 Cremophor A 6 Ceteareth-6, stearyl alcohol 1.50 Cremophor A 25 Ceteareth-25 0.50 beeswax 3044 PH Bees Wax 3.00 Lanette O Cetearyl Alcohol 10.00 Miglyol 812 Caprylic / Capric Triglycerides D 1.00 vitamin E acetate Tocopheryl acetate 1.0% VERB. (V) 0.20 bisabolol rac. bisabolol A 25.00 Dow Corning 345 Fluid Cyclopentasiloxanes, cyclohexasiloxanes 20.00 Dow Corning 245 Fluid Cyclopentasiloxane 8,00 Uvinul MC 80 Ethylhexyl methoxycinnamate 4.00 Abil EM 90 Cetyl PEG / PPG-10/1 dimethicone 7.00 T-Lite SF Titanium Dioxide, Alumina Hydrate, Dimethicone / Methicone Copolymer B 17.00 Ethanol 95% Alcohol 10.00 Z-COTE MAX Zinc Oxide (and) Diphenyl Capryl Methicone 4.50 water to the. Aqua the. 3.00 Glycerin 87% glycerin 0.5% VERB. (V) 1.00 talc Talc A 25.00 Dow Corning 345 Fluid Cyclopentasiloxanes, cyclohexasiloxanes 20.00 Dow Corning 245 Fluid Cyclopentasiloxane 8,00 Uvinul MC 80 Ethylhexyl methoxycinnamate 4.00 Abil EM 90 Cetyl PEG / PPG-10/1 dimethicone 7.00 T-Lite SF-S Titanium Dioxide, Silica Hydrate, Alumina Hydrate, Methicone / Dimethicone Copolymer B 17.00 Ethanol 95% Alcohol 9.99 Z-COTE MAX Zinc Oxide (and) Diphenyl Capryl Methicone 5.00 water to the. Aqua the. 3.00 Glycerin 87% glycerin 0.01% VERB. (V) 1.00 talc Talc A 20.00 Dow Corning 345 Fluid Cyclopentasiloxanes, cyclohexasiloxanes 10.00 Dow Corning 245 Fluid Cyclopentasiloxane 7,50 Uvinul MC 80 Ethylhexyl methoxycinnamate 2.00 Uvinul T 150 Ethylhexyl triazone 12.00 Cosmacol EMI Di-C12-13 alkyl malate 4.00 Abil EM 90 Cetyl PEG / PPG-10/1 dimethicone B 7,00 T-Lite SF Titanium Dioxide, Alumina Hydrate, Dimethicone / Methicone Copolymer C 15.00 ethanol 95% Alcohol 10.00 Z-COTE MAX Zinc Oxide (and) Diphenyl Capryl Methicone 3.00 Glycerin 87% glycerin 1.5% VERB. (V) 8.00 water to the. Aqua the. A 20.00 Dow Corning 345 Fluid Cyclopentasiloxanes, cyclohexasiloxanes 10.00 Dow Corning 245 Fluid Cyclopentasiloxane 7,50 Uvinul MC 80 Ethylhexyl methoxycinnamate 2,00 Tinosorb S Bis-Ethylhexyloxyphenol Methoxyphenyl Triazines 12.00 Cosmacol EMI Di-C12-13 alkyl malate 4.00 Abil EM 90 Cetyl PEG / PPG-10/1 dimethicone B 7,00 T-Lite SF Titanium Dioxide, Alumina Hydrate, Dimethicone / Methicone Copolymer C 15.00 ethanol 95% Alcohol 10.00 Z-COTE MAX Zinc Oxide (and) Diphenyl Capryl Methicone 3.00 Glycerin 87% glycerin 0.5% VERB. (V) 9.00 water to the. Aqua the. A 2.00 Cremophor WO 7 PEG-7 Hydrogenated Castor Oil 6.00 Abil B 8839 Cyclopentasiloxanes, cyclohexasiloxanes 3.00 T-Lite SF Titanium Dioxide, Alumina Hydrate, Dimethicone / Methicone Copolymer 4.00 isopropyl palmitate Isopropyl palmitate 1.00 Abil 350 Dimethicone B 7,00 Uvinul MC 80 Ethylhexyl methoxycinnamate 1.00 Uvinul T 150 Ethylhexyl triazone 7,00 Finsolv TN C12-15 alkyl benzoates 4.00 Abil WE 09 Polyglyceryl-4 isostearates, Cetyl PEG / PPG-10/1 Dimethicone, Hexyl Laurate C 0.50 sodium chloride Sodium Chloride 0.20 Edeta BD Disodium EDTA 61.30 water. Aqua the D 1.00 vitamin E acetate Tocopheryl acetate 1.0% VERB. (V) qs preservative A 2.00 Cremophor WO 7 PEG-7 Hydrogenated Castor Oil 6.00 Abil B 8839 Cyclopentasiloxanes, cyclohexasiloxanes 3.00 Z-COTE MAX Zinc Oxide (and) Diphenyl Capryl Methicone 4.00 isopropyl palmitate Isopropyl palmitate 1.00 Abil 350 Dimethicone B 7,00 Uvinul MC 80 Ethylhexyl methoxycinnamate 1.00 Uvinul T 150 Ethylhexyl triazone 7,00 Finsolv TN C12-15 alkyl benzoates 4.00 Abil WE 09 Polyglyceryl-4 isostearates, Cetyl PEG / PPG-10/1 Dimethicone, Hexyl Laurate C 0.50 sodium chloride Sodium Chloride 0.20 Edeta BD Disodium EDTA 62.20 water. Aqua the D 1.00 vitamin E acetate Tocopheryl acetate 0.1% VERB. (V) qs preservative A 2.00 Cremophor WO 7 PEG-7 Hydrogenated Castor Oil 6.00 Abil B 8839 Cyclopentasiloxanes, cyclohexasiloxanes 3.00 Z-COTE MAX Zinc Oxide (and) Diphenyl Capryl Methicone 4.00 isopropyl palmitate Isopropyl palmitate 1.00 Abil 350 Dimethicone B 7,00 Uvinul MC 80 Ethylhexyl methoxycinnamate 1,00 Tinosorb S Bis-Ethylhexyloxyphenol Methoxyphenyl Triazines 7,00 Finsolv TN C12-15 alkyl benzoates 4.00 Abil WE 09 Polyglyceryl-4 isostearates, cetyl PEG / PPG-10/1 Dimethicone, Hexyl Laurate C 0.50 sodium chloride Sodium Chloride 0.20 Edeta BD Disodium EDTA 60,30 water the. Aqua the D 1.00 vitamin E acetate Tocopheryl acetate 2, 0% VERB. (V) qs preservative A 2.00 Cremophor WO 7 PEG-7 Hydrogenated Castor Oil 6.00 Abil B 8839 Cyclopentasiloxanes, cyclohexasiloxanes 6.00 Z-COTE MAX Zinc Oxide (and) Diphenyl Capryl Methicone 4.00 isopropyl palmitate Isopropyl palmitate 1.00 Abil 350 Dimethicone B 4,00 Uvinul N 539 T Octocrylene 1,00 Tinosorb S Bis-Ethylhexyloxyphenol Methoxyphenyl Triazines 7,00 Finsolv TN C12-15 alkyl benzoates 4.00 Abil WE 09 Polyglyceryl-4 isostearates, Cetyl PEG / PPG-10/1 Dimethicone, Hexyl Laurate C 0.50 sodium chloride Sodium Chloride 0.20 Edeta BD Disodium EDTA 62.10 water. Aqua the D 1.00 vitamin E acetate Tocopheryl acetate 0.2% VERB. (V) qs preservative A 2.00 Cremophor WO 7 PEG-7 Hydrogenated Castor Oil 6.00 Abil B 8839 Cyclopentasiloxanes, cyclohexasiloxanes 6.00 Z-COTE MAX Zinc Oxide (and) Diphenyl Capryl Methicone 4.00 isopropyl palmitate Isopropyl palmitate 1.00 Abil 350 Dimethicone B 3.00 Uvinul N 539 T Octocrylene 1.00 Mexoryl XL Drometrizole trisiloxanes 1,00 Tinosorb S Bis-Ethylhexyloxyphenol Methoxyphenyl Triazines 7,00 Finsolv TN C12-15 alkyl benzoates 4.00 Abil WE 09 Polyglyceryl-4 isostearates, Cetyl PEG / PPG-10/1 Dimethicone, Hexyl Laurate C 0.50 sodium chloride Sodium Chloride 0.20 Edeta BD Disodium EDTA 1.0% VERB. (V) 61.30 water. Aqua the D 1.00 vitamin E acetate Tocopheryl acetate qs preservative A 2.00 Cremophor WO 7 PEG-7 Hydrogenated Castor Oil 6.00 Abil B 8839 Cyclopentasiloxanes, cyclohexasiloxanes 6.00 T-Lite SF-S Titanium Dioxide, Silica Hydrate, Alumina Hydrate, Methicone / Dimethicone Copolymer 4.00 isopropyl palmitate Isopropyl palmitate 1.00 Abil 350 Dimethicone B 3.00 Uvinul N 539 T Octocrylene 1.00 Mexoryl XL Drometrizole trisiloxane 1,00 Tinosorb S Bis-Ethylhexyloxyphenol Methoxyphenyl Triazines 7,00 Finsolv TN C12-15 alkyl benzoates 4.00 Abil WE 09 Polyglyceryl-4 isostearates, Cetyl PEG / PPG-10/1 Dimethicone, Hexyl Laurate C 0.50 sodium chloride Sodium Chloride 0.20 Edeta BD Disodium EDTA 61.80 water. Aqua the D 1.00 vitamin E acetate Tocopheryl acetate 0.5% VERB. (V) qs preservative A 4.50 Uvinul MC 80 Ethylhexyl methoxycinnamate 3.00 Uvinul N 539 T Octocrylene 1.00 Uvinul T 150 Ethylhexyl triazone 2.50 Cosmacol EMI Di-C12-13 alkyl malate B 0.50 vitamin E acetate Tocopheryl acetate 4.00 Tego Care 450 Polyglyceryl-3 Methyl Glucose Distearate C 3.50 Cetiol SN Cetearyl Isononanoate 1.00 Ganex V-220 VP / eicosene copolymer 5.00 isohexadecane Isohexadecane 2.50 Cosmacol EMI Di-C12-13 alkyl malate 5.00 Z-COTE MAX Zinc Oxide (and) Diphenyl Capryl Methicone D 44,00 water the. Aqua the. 5.00 Glycerin 87% glycerin 1,00 Lanette E Sodium Cetearyl Sulfate 15.00 Luviquat Care Polyquaternium-44 1.0% VERB. (V) 0.50 Keltrol Xanthan gum E 1.00 phenonip A 4.50 Uvinul MC 80 Ethylhexyl methoxycinnamate 3.00 Uvinul N 539 T Octocrylene 1,00 Tinosorb S Bis-ethoxylhexyloxyphenol Methoxyphenyl triazines 2.50 Cosmacol EMI Di-C12-13 alkyl malate B 0.50 vitamin E acetate Tocopheryl acetate 4.00 Tego Care 450 Polyglyceryl-3 Methyl Glucose Distearate C 3.50 Cetiol SN Cetearyl Isononanoate 1.00 Ganex V-220 VP / eicosene copolymer 5.00 isohexadecane Isohexadecane 2.50 Cosmacol EMI Di-C12-13 alkyl malate 5.00 Z-COTE MAX Zinc Oxide (and) Diphenyl Capryl Methicone D 44,90 water the. Aqua the. 5.00 Glycerin 87% glycerin 1,00 Lanette E Sodium Cetearyl Sulfate 15.00 Luviquat Care Polyquaternium-44 0.1% VERB. (V) 0.50 Keltrol Xanthan gum E 1.00 phenonip A 1.50 Mexoryl XL Drometrizole trisoloxanes 5,00 Uvinul N 539 T Octocrylene 1,00 Tinosorb S Bis-Ethylhexyloxyphenol Methoxyphenyl Triazines 2.50 Cosmacol EMI Di-C12-13 alkyl malate b0.50 vitamin E acetate Tocopheryl acetate 4.00 Tego Care 450 Polyglyceryl-3 Methyl Glucose Distearate C 3.50 Cetiol SN Cetearyl Isononanoate 1.00 Ganex V-220 VP / eicosene copolymer 5.00 isohexadecane Isohexadecane 2.50 Cosmacol EMI Di-C12-13 alkyl malate 5.00 Z-COTE MAX Zinc Oxide (and) Diphenyl Capryl Methicone D 44,50 water the. Aqua the. 5.00 Glycerin 87% glycerin 1,00 Lanette E Sodium Cetearyl Sulfate 15.00 Luviquat Care Polyquaternium-44 1.5% VERB. (V) 0.50 Keltrol Xanthan gum E 1.00 phenonip A 1.50 Mexoryl XL Drometrizole trisoloxanes 5,00 Uvinul N 539 T Octocrylene 1,00 Tinosorb S Bis-Ethylhexyloxyphenol Methoxyphenyl Triazines 2.50 Cosmacol EMI Di-C12-13 alkyl malate B 0.50 vitamin E acetate Tocopheryl acetate 4.00 Tego Care 450 Polyglyceryl-3 Methyl Glucose Distearate C 3.50 Cetiol SN Cetearyl Isononanoate 1.00 Ganex V-220 VP / eicosene copolymer 5.00 isohexadecane Isohexadecane 2.50 Cosmacol EMI Di-C12-13 alkyl malate 5.00 T-Lite SF Titanium Dioxide, Alumina Hydrate, Dimethicone / Methicone Copolymer D 45,00 water the. Aqua the. 5.00 Glycerin 87% glycerin 1,00 Lanette E Sodium Cetearyl Sulfate 15.00 Luviquat Care Polyquaternium-44 1.0% VERB. (V) 0.50 Keltrol Xanthan gum E 1.00 phenonip A 1.00 Abil Care 85 Bis-PEG / PPG-16/16 PEG / PPG-16/16 Dimethicones, Caprylic / Capric Triglycerides 3.00 Cremophor CO 40 PEG-40 Hydrogenated Castor Oil 0.30 Cremophor WO 7 PEG-7 Hydrogenated Castor Oil 5.00 Uvinul MC 80 Ethylhexyl methoxycinnamate 10.00 Witconol APM PPG-3 myristyl ether 2.00 Uvinul T 150 Ethylhexyl triazone 1.00 Dow Corning 345 Fluid Cyclopentasiloxanes, cyclohexasiloxanes 5,00 Uvinul N 539 T Octocrylene B 5.00 Z-COTE MAX Zinc Oxide Q (and) Diphenyl Capryl Methicone C 5.00 1,2-propylene glycol Propylene glycol 0.20 Keltrol Xanthan gum 0.10 Edeta BD Disodium EDTA 2.0% VERB. (V) 1,50 Simulgel 600 Acrylamide / sodium acryloyldimethyltaurate copolymer, isohexadecane, polysorbate 80 58.40 water. Aqua the. D qs perfume oil 0.50 glydant DMDM hydantoin A 2,00 Abil Care 85 Bis-PEG / PPG-16/16 PEG / PPG-16/16 Dimethicones, Caprylic / Capric Triglycerides 4,00 Finsolv TN C12-15 alkyl benzoates 1.50 Miglyol 812 Caprylic / Capric Triglycerides 0.50 vitamin E acetate Tocopheryl acetate 7,50 Uvinul MC 80 Ethylhexyl methoxycinnamate 4.00 Cetiol B Dibutyl adipate 3.00 Luvitol EHO Cetearyl ethylhexanoate 1.00 Cremophor CO 40 PEG-40 Hydrogenated Castor Oil 1,00 paraffin oil, fluid Mineral oil 3.00 Plantacare 2000 Decyl glucosides 0.50 phenonip qs perfume oil B 4.00 Z-COTE MAX Zinc Oxide (and) Diphenyl Capryl Methicone C 2.00 Simulgel NS Hydroxyethyl acrylate / sodium acryloyl dimethyl taurate copolymer, squalane, polysorbate 60 0.20 Keltrol Xanthan gum 0.10 Edeta BD Disodium EDTA 1.0% VERB. (V) 64.20 water to the. Aqua the A 6,00 Gilugel SIL 5 Cyclomethicone (and) Aluminum / Magnesium Hydroxide Stearate 5.00 Uvinul MC 80 Ethylhexyl methoxycinnamate 2.00 Uvinul A Plus Diethylamino hydroxybenzoyl hexyl benzoate 1.00 Uvinul T 150 Ethylhexyl triazone 7,00 Finsolv TN C12-15 alkyl benzoates 4.00 Abil WE 09 Polyglyceryl-4 isostearates, Cetyl PEG / PPG-10/1 Dimethicone, Hexyl Laurate 2.00 Cosmacol EMI Di-C12-13 alkyl malate 3.00 isopropalmitate Isopropyl palmitate 5.00 Abil B 8839 Cyclopentasiloxanes, cyclohexasiloxanes 0.50 Abil 350 Dimethicone B 0.50 sodium chloride Sodium Chloride 0.20 Edeta BD Disodium EDTA 0.2% VERB. (V) 62.10 water. Aqua the. C 1.00 vitamin E acetate Tocopheryl acetate 0.50 phenonip A 4.50 Uvinul MC 80 Ethylhexyl methoxycinnamate 2,00 Tinosorb S Bis-Ethylhexyloxyphenol Methoxyphenyl Triazines 3.00 Uvinul N 539 T Octocrylene 2.50 Cosmacol EMI Di-C12-13 alkyl malate 0.50 vitamin E acetate Tocopheryl acetate 4.00 Tego Care 450 Polyglyceryl-3 Methyl Glucose Distearate B 3.50 Cetiol SN Cetearyl Isononanoate 1.00 Ganex V-220 VP / eicosene copolymer 5.00 isohexadecane Isohexadecane 2.50 Cosmacol EMI Di-C12-13 alkyl malate 3.00 T-Lite SF Titanium Dioxide, Alumina Hydrate, Dimethicone / Methicone Copolymer C 5.00 Glycerin 87% glycerin 1,00 Lanette E Sodium Cetearyl Sulfate 0.50 Keltrol Xanthan gum 1.0% VERB. (V) 59,70 water the. Aqua the. D 1.00 Phenonip 0.30 bisabolol rac. bisabolol A 2,00 Abil Care 85 Bis-PEG / PPG-16/16 PEG / PPG-16/16 Dimethicones, Caprylic / Capric Triglycerides 4,00 Finsolv TN C12-15 alkyl benzoates 1.50 Miglyol 812 Caprylic / Capric Triglycerides 0.50 vitamin E acetate Tocopheryl acetate 7,50 Uvinul MC 80 Ethylhexyl methoxycinnamate 4.00 Cetiol B Dibutyl adipate 1.00 Luvitol EHO Cetearyl ethylhexanoate 1.00 Cremophor CO 40 PEG-40 Hydrogenated Castor Oil 1,00 paraffin oil, fluid Mineral oil 3.00 Plantacare 2000 Decyl glucosides 1.00 Uvinul A Plus Diethylamino hydroxybenzoyl hexyl benzoate 0.50 phenonip 2.50 Uvinul T 150 Ethylhexyl triazone qs perfume oil B 4.00 Z-COTE MAX Zinc Oxide (and) Diphenyl Capryl Methicone C 2.00 Simulgel NS Hydroxyethyl acrylate / sodium acryloyl dimethyl taurate copolymer, squalane, polysorbate 60 0.10 Keltrol Xanthan gum 0.10 Edeta BD Disodium EDTA 0.5% VERB. (V) 59.90 water to the Aqua the. A 4,00 Eumulgin VL 75 Lauryl glucoside, polyglyceryl-2 dipolyhydroxystearates, glycerin 2,00 Lanette O Cetearyl Alcohol 12.00 Myritol 331 Cocoglycerides 8.00 Finsolv TN C12-15 alkyl benzoates 8.00 Cetiol B Dibutyl adipate B 6.00 T-Lite SF Titanium Dioxide, Alumina Hydrate, Dimethicone / Methicone Copolymer 5.00 Z-COTE MAX Zinc Oxide (and) Diphenyl Capryl Methicone C 3.00 Glycerin 87% glycerin 0.10 Edeta BD Disodium EDTA 1.50 Veegum Ultra Magnesium Aluminum Silicate 1,50 Lanette E Sodium Cetearyl Sulfate 2.0% VERB. (V) 0.30 Keltrol Xanthan gum 45.10 water to the. Water D 1.00 Phenonip Phenoxyethanol, methylparaben, ethylparaben, butylparaben, propylparaben, isobutylparaben A 4,00 Eumulgin VL 75 Lauryl glucoside, polyglyceryl-2 dipolyhydroxystearates, glycerin 2,00 Lanette O Cetearyl Alcohol 12.00 Myritol 331 Cocoglycerides 8.00 Finsolv TN C12-15 alkyl benzoates 8.00 Cetiol B Dibutyl adipate B 6.00 Uvinul N 539 T Octocrylene 5.00 Z-COTE MAX Zinc Oxide (and) Diphenyl Capryl Methicone C 3.00 Glycerin 87% glycerin 0.10 Edeta BD Disodium EDTA 1.50 Veegum Ultra Magnesium Aluminum Silicate 1,50 Lanette E Sodium Cetearyl Sulfate 0.30 Carbopol Ultrez 10 P Carbomer 1.0% VERB. (V) 46.10 water to the. Aqua the. D 1.00 Phenonip Phenoxyethanol, methylparaben, ethylparaben, butylparaben, propylparaben, isobutylparaben A 4,00 Eumulgin VL 75 Lauryl glucoside, polyglyceryl-2 dipolyhydroxystearates, glycerin 2,00 Lanette O Cetearyl Alcohol 10.00 Myritol 331 Cocoglycerides 8.00 Finsolv TN C12-15 alkyl benzoates 8.00 Cetiol B Dibutyl adipate B 2.00 Uvinul A Plus Diethylamino hydroxybenzoyl hexyl benzoate 5.00 Z-COTE MAX Zinc Oxide (and) Diphenyl Capryl Methicone C 3.00 Glycerin 87% glycerin 0.10 Edeta BD Disodium EDTA 1.50 Veegum Ultra Magnesium Aluminum Silicate 1,50 Lanette E Sodium Cetearyl Sulfate 5.0% VERB. (V) 0.30 Carbopol Ultrez 10 P Carbomer add water to that. Water D 1.00 Phenonip Phenoxyethanol, methylparaben, ethylparaben, butylparaben, propylparaben, isobutylparaben A 3.50 Cremophor A 6 Ceteareth-6, stearyl alcohol 1.50 Cremophor A 25 Ceteareth-25 7,50 Uvinul MC 80 Ethylhexyl methoxycinnamate 2.00 Uvinul A Plus Diethylamino hydroxybenzoyl hexyl benzoate 2.00 Dow Corning 345 Cyclopentasiloxanes, cyclohexasiloxanes fluid 0.50 beeswax 3044 PH Bees Wax 3.00 Lanette O Cetearyl Alcohol 10.00 Miglyol 812 Caprylic / Capric Triglycerides B 5.00 T-Lite SF-S Titanium Dioxide, Silica Hydrate, Alumina Hydrate, Methicone / Dimethicone Copolymer C 3.00 Glycerin 87% glycerin 0.20 Edeta BD Disodium EDTA 0.30 Keltrol T Xanthan gum 1.00 Plantacare 2000 Decyl glucosides 2.0% VERB. (V) 57.30 water. Aqua the. D 1.00 vitamin E acetate Tocopheryl acetate 0.20 bisabolol rac. bisabolol A 10,00 Uvinul A Plus B Ethylhexyl methoxycinnamate, diethylamino hydroxybenzoyl hexyl benzoate 10,00 Uvinul N 539 T Octocrylene 4.00 Eumulgin VL 75 Lauryl glucoside, polyglyceryl-2 dipolyhydroxystearates, glycerin 8.00 Cetiol B Dibutyl adipate 8.00 Finsolv TN C12-15 alkyl benzoates 12.00 Myritol 331 Cocoglycerides 1,00 Lanette E Sodium Cetearyl Sulfate 2,00 Lanette O Cetearyl Alcohol B 3.00 Z-COTE MAX Zinc Oxide (and) Diphenyl Capryl Methicone C 35,08 water the. Aqua the. 0.38 citric acid Citric Acid 2.9% glycerol 87% glycerin 0.05 Edeta BD Disodium EDTA 0.20 allantoin allantoin 0.30 Keltrol Xanthan gum 0.1% VERB. (V) 1.50 Veegum Ultra Magnesium Aluminum Silicate D 0.50 Phenonip 1.00 vitamin E acetate Tocopheryl acetate A 0.70 Cremophor A 25 Cremophor A 6 Ceteareth-25 1.70 Ceteareth-6, stearyl alcohol 2.00 Uvinul A Plus Diethylamino hydroxybenzoyl hexyl benzoate 3.00 Uvinul N 539 T Octocrylene 3.00 Z-COTE MAX Zinc oxides (and) diphenyl caprylmethicone 2.00 Abil B 8843 PEG-14 Dimethicone 3,60 Lanette O Cetearyl Alcohol 4.00 Uvinul MC 80 Ethylhexyl methoxycinnamate 2.00 Cetiol B Dibutyl adipate B 4.00 Glycerin 87% glycerin 0.20 Edeta BD Disodium EDTA 71.00 water to the. panthenol C 4.00 Luvigel EM Caprylic / Capric Triglyceride, Sodium Acrylate Copolymer D 1.00 vitamin E acetate Tocopheryl acetate 1.0% VERB. (V) 0.20 bisabolol rac. bisabolol qs preservative A 7.50 Uvinul MC 80 Ethylhexyl methoxycinnamate 5,00 Uvinul N 539 T Octocrylene 3.00 Emulgade PL 68/50 Cetearyl Glucoside, Cetearyl Alcohol 2.00 Dracorin 100 SE Glyceryl Stearate, PEG-100 Stearate 1.00 Fitoderm Squalane 0.50 Cremophore WO 7 PEG-7 Hydrogenated Castor Oil 0.50 Cremophor PS 20 Polysorbate 20 2.00 Dry Flo Pure Aluminum Starch Octenylsuccinate B 5.00 Z-COTE MAX Zinc Oxide (and) Diphenyl Capryl Methicone 0.03 Sicomet Blue P 77 007 CI 77 007, Ultramarines C 4.00 1,2-propylene glycol Care Propylene glycol 2,00 D-Panthenol 50 P Panthenol, Propylene Glycol 0.20 Keltrol Xanthan gum 0,50 Simulgel 600 Acrylamide / sodium acryloyldimethyltaurate copolymer, isohexadecane, polysorbate 80 0.5% VERB. (V) 65.27 water. Aqua the. qs preservative 0.50 vitamin E acetate Tocopheryl acetate A 6,00 Gilugel SIL 5 Cyclomethicone (and) Aluminum / Magnesium Hydroxide Stearate 5,00 Uvinul N 539 T Mexoryl XL Octocrylene 2.00 Drometrizole trisiloxanes 1.00 Uvinul T 150 Ethylhexyl triazone 3.00 T-Lite SF-S Titanium Dioxide, Silica Hydrate, Alumina Hydrate, Methicone / Dimethicone Copolymer 5.00 Finsolv TN C12-15 alkyl benzoates 4.00 Abil WE 09 Polyglyceryl-4 isostearates, Cetyl PEG / PPG-10/1 Dimethicone, Hexyl Laurate 2.00 Cosmacol EMI Di-C12-13 alkyl malate 3.00 isopropalmitate Isopropyl palmitate 5.00 Abil B 8839 Cyclopentasiloxanes, cyclohexasiloxanes 0.50 Abil 350 Dimethicone B 0.50 sodium chloride Sodium Chloride 0.20 Edeta BD Disodium EDTA 1.0% VERB. (V) 61.30 water. Aqua the. C 1.00 vitamin E acetate Tocopheryl acetate 0.50 phenonip A 1.00 Abil Care 85 Bis-PEG / PPG-16/16 PEG / PPG-16/16 Dimethicones, Caprylic / Capric Triglycerides 3.00 Cremophor CO 40 PEG-40 Hydrogenated Castor Oil 0.30 Cremophor WO 7 PEG-7 Hydrogenated Castor Oil 5,00 Uvinul N 539 T Octocrylene 10.00 Witconol APM PPG-3 myristyl ether 2.00 Uvinul T 150 Ethylhexyl triazone 1.00 Dow Corning 345 Fluid Cyclopentasiloxanes, cyclohexasiloxanes 2.00 Uvinul A Plus Diethylamino hydroxybenzoyl hexyl benzoate B 5.00 Z-COTE MAX Zinc oxides (and) diphenyl capryl silanes C 5.00 1,2-propylene glycol Propylene glycol 0.20 Keltrol Xanthan gum 0.10 Edeta BD Disodium EDTA 1.0% VERB. (V) 1,50 Simulgel 600 Acrylamide / sodium acryloyldimethyltaurate copolymer, isohexadecane, polysorbate 80 59.40 water to the. Aqua the. D qs perfume oil 0.50 glydant DMDM hydantoin A 7,00 Uvinul A Plus B Ethylhexyl methoxycinnamate, diethylamino hydroxybenzoyl hexyl benzoate 1,00 Tinosorb S Bis-Ethylhexyloxyphenol Methoxyphenyl Triazines 1.00 Uvinul T 150 Ethylhexyl triazone 7,00 Uvinul N 539 T Octocrylene 4.00 Eumulgin VL 75 Lauryl glucoside, polyglyceryl-2 dipolyhydroxystearates, glycerin 8.00 Cetiol B Dibutyl adipate 8.00 Finsolv TN C12-15 alkyl benzoates 12.00 Myritol 331 Cocoglycerides 1,00 Lanette E Sodium Cetearyl Sulfate 2,00 Lanette O Cetearyl Alcohol B 5.00 Z-COTE MAX Zinc Oxide (and) Diphenyl Capryl Methicone C 35,35 water. Aqua the. 3.00 Glycerin 87% glycerin 0.05 Edeta BD Disodium EDTA 0.20 allantoin allantoin 0.30 Keltrol Xanthan gum 0.1% VERB. (V) 1.50 Veegum Ultra Magnesium Aluminum Silicate D 0.50 Phenonip 1.00 vitamin E acetate Tocopheryl acetate A 7,00 Uvinul A Plus B Ethylhexyl methoxycinnamate, diethylamino hydroxybenzoyl hexyl benzoate 1,00 Tinosorb S Bis-Ethylhexyloxyphenol Methoxyphenyl Triazines 1.00 Uvinul T 150 Ethylhexyl triazone 7,00 Uvinul N 539 T Octocrylene 4.00 Eumulgin VL 75 Lauryl glucoside, polyglyceryl-2 dipolyhydroxystearates, glycerin 8.00 Cetiol B Dibutyl adipate 8.00 Finsolv TN C12-15 alkyl benzoates 12.00 Myritol 331 Cocoglycerides 1,00 Lanette E Sodium Cetearyl Sulfate 2,00 Lanette O Cetearyl Alcohol B 5.00 T-Lite SF Titanium Dioxide, Alumina Hydrate, Dimethicone / Methicone Copolymer C 30,45 water. Aqua the. 3.00 Glycerin 87% glycerin 0.05 Edeta BD Disodium EDTA 0.20 allantoin allantoin 0.30 Keltrol Xanthan gum 5.0% VERB. (V) 1.50 Veegum Ultra Magnesium Aluminum Silicate D 0.50 Phenonip 1.00 vitamin E acetate Tocopheryl acetate 5.00 Z-COTE MAX Zinc Oxide (and) Diphenyl Capryl Methicone 2.00 Uvinul A Plus Diethylamino hydroxybenzoyl hexyl benzoate 2.00 Mexoryl XI Drometrizole trisiloxanes 3.00 Uvinul MC 80 Ethylhexyl methoxycinnamate 0.50 Abil 350 Dimethicone 2.75 carnic wax IT 20 Carnauba (Copernica cerifera) wax, paraffins 3.70 candelilla wax IT 281 LJ Candelilla (Euphorbia cerifera) Wax 1.80 beeswax 3050 PH Bees Wax 3.20 TeCero Wax 30445 Microcrystalline wax 3.20 TeCero wax 1030K Microcrystalline wax 1.34 Cutina OP Cetyl palmitate 6.40 Vaseline petrolatum 7,30 Softisan 100 Hydrogenated Coco-Glycerides 10.00 Luvitol EHO Cetearyl ethylhexanoate 0.17 bisabolol nat. bisabolol 1.84 vitamin E acetate Tocopheryl acetate 1.0% VERB. (V) 0.42 D, L-alpha-tocopherol tocopherol 40.38 castor oil Castor (Ricinus communis) Oil A 1.00 Abil Care 85 Bis-PEG / PPG-16/16 PEG / PPG-16/16 Dimethicones, Caprylic / Capric Triglycerides 3.00 Cremophor CO 40 PEG-40 Hydrogenated Castor Oil 0.30 Cremophor WO 7 PEG-7 Hydrogenated Castor Oil 2,00 Mexoryl XL Drometrizole Trisilioxane 10.00 Witconol APM PPG-3 myristyl ether 1.00 Uvinul T 150 Ethylhexyl triazone 1.00 Dow Corning 345 Fluid Cyclopentasiloxanes, cyclohexasiloxanes 5,00 Uvinul N 539 T Octocrylene B 3.00 T-Lite SF-S Titanium Dioxide, Silica Hydrate, Alumina Hydrate, Methicone / Dimethicone Copolymer C 5.00 1,2-propylene glycol Propylene glycol 1.00 Mexoryl SX Terephthalidene Dicamphor Sulfanic Acid 0.20 Keltrol Xanthan gum 0.10 Edeta BD Disodium EDTA 1.0% VERB. (V) 1,50 Simulgel 600 Acrylamide / sodium acryloyldimethyltaurate copolymer, isohexadecane, polysorbate 80 69.50 water to the. Aqua the. D qs perfume oil 0.50 glydant DMDM hydantoin A 1.00 Abil Care 85 Bis-PEG / PPG-16/16 PEG / PPG-16/16 Dimethicones, Caprylic / Capric Triglycerides 3.00 Cremophor CO 40 PEG-40 Hydrogenated Castor Oil 0.30 Cremophor WO 7 PEG-7 Hydrogenated Castor Oil 2.00 Parsol 1789 Butyl methoxydibenzoylmethane 2,00 Mexoryl XL Drometrizole Trisilioxane 10.00 Witconol APM PPG-3 myristyl ether 1.00 Uvinul T 150 Ethylhexyl triazone 1.00 Dow Corning 345 Fluid Cyclopentasiloxanes, cyclohexasiloxanes 5,00 Uvinul N 539 T Octocrylene B 3.00 T-Lite SF-S Titanium Dioxide, Silica Hydrate, Alumina Hydrate, Methicone / Dimethicone Copolymer C 5.00 1,2-propylene glycol Propylene glycol 1.00 Mexoryl SX Terephthalidene Dicamphor Sulfanic Acid 0.20 Keltrol Xanthan gum 0.10 Edeta BD Disodium EDTA 0.2% VERB. (V) 1,50 Simulgel 600 Acrylamide / sodium acryloyldimethyltaurate copolymer, isohexadecane, polysorbate 80 68.30 water. Aqua the. D qs perfume oil 0.50 glydant DMDM hydantoin A 0.70 Cremophor A 25 Ceteareth-25 1.70 Cremophor A 6 Ceteareth-6, stearyl alcohol 2.00 Parsol 1789 Butyl methoxydibenzoylmethane 5,00 Uvinul N 539 T Octocrylene 4.00 Z-COTE MAX Zinc oxides (and) diphenyl caprylmethicone 2.00 Abil B 8843 PEG-14 Dimethicone 3,60 Lanette O Cetearyl Alcohol 1.00 Uvinul T150 Ethylhexyl triazone 2.00 Cetiol B Dibutyl adipate B 4.00 Glycerin 87% glycerin 0.20 Edeta BD Disodium EDTA 71.00 water to the. panthenol C 4.00 Luvigel EM Caprylic / Capric Triglyceride, Sodium Acrylate Copolymer 1.0% VERB. (V) D 1.00 vitamin E acetate Tocopheryl acetate 0.20 bisabolol rac. bisabolol qs preservative A 1.00 Abil Care 85 Bis-PEG / PPG-16/16 PEG / PPG-16/16 Dimethicones, Caprylic / Capric Triglycerides 3.00 Cremophor CO 40 PEG-40 Hydrogenated Castor Oil 0.30 Cremophor WO 7 PEG-7 Hydrogenated Castor Oil 2.00 Parsol 1789 Butyl methoxydibenzoylmethane 2,00 Mexoryl XL Drometrizole Trisilioxane 10.00 Witconol APM PPG-3 myristyl ether 1.00 Uvinul T 150 Ethylhexyl triazone 1.00 Dow Corning 345 Fluid Cyclopentasiloxanes, cyclohexasiloxanes 5,00 Uvinul N 539 T Octocrylene B 3.00 Z-COTE MAX Zinc Oxide (and) Diphenyl Capryl Methicone C 5.00 1,2-propylene glycol Propylene glycol 1.00 Mexoryl SX Terephthalidene Dicamphor Sulfanic Acid 0.20 Keltrol Xanthan gum 0.10 Edeta BD Disodium EDTA 1,50 Simulgel 600 Acrylamide / sodium acryloyldimethyltaurate copolymer, isohexadecane, polysorbate 80 0.5% VERB. (V) 68.00 water to the. Aqua the. D qs perfume oil 0.50 glydant DMDM hydantoin A 2,00 Uvinul A Plus Diethylamino hydroxybenzoyl hexyl benzoate 3.00 Uvinul N 539 T Octocrylene 3.00 Emulgade PL 68/50 Cetearyl Glucoside, Cetearyl Alcohol 2.00 Dracorin 100 SE Glyceryl Stearate, PEG-100 Stearate 1.00 Fitoderm Squalane 0.5 cremophore WO 7 PEG-7 Hydrogenated Castor Oil 0.5 Cremophor PS 20 Polysorbate 20 2.00 Dry Flo Pure Aluminum Starch Octenylsuccinate B 5.00 Z-COTE MAX Zinc oxides (and) diphenyl caprylmethicone C 4.00 1,2-propylene glycol care Propylene glycol 0.20 Keltrol Xanthan gum 0,50 Simulgel 600 Acrylamide / sodium acryloyldimethyltaurate copolymer, isohexadecane, polysorbate 80 65.80 water. Aqua the. D 0.50 Euxyl K 300 0.50 vitamin E acetate Tocopheryl acetate 1.0% VERB. (V) 1,00 RetiSTAR Caprylic / Capric Triglycerides, Sodium Ascorbate, Tocopherol, Retinol

Example 38

Determination of the antioxidant effect of 3,3'-Dihydroxyisorenieratene in the peroxide suspension test

Cumen was mixed in a closed vessel at 37 ° C with a free radical generator. For this purpose, 5 ml of cumene were mixed with 4 ml of chlorobenzene and the reaction started with 1 ml of 0.45 M solution of 2,2'-azobis (2,4-dimehtylvaleronitrile) (AMVN) in chlorobenzene. The reaction mixture was stirred well and tempered through a thermostat. As a result, the reaction yielded concentrations of 3.6 mol / L cumene and 45 mmol / L AMVN. The formation of cumene hydroperoxides was determined by High Preformance Liquid Chromatography (HPLC) by removing 50 μl samples from the vessel through a septum and a mobile phase of hexane and isopropanol in a volume ratio of 99 to 1 and a flow rate of 2 ml was passed over a silica gel column per minute. The column had the dimensions: 150 × 6.0 mm - 5 μm, the grain size of the column packing was 5 μm. Cumen hydroperoxide formed by the reaction and a by-product were detected at a wavelength of 254 nm and a retention time of 2.285 and 2.405 minutes, respectively. The area of these double peaks was plotted against the reaction time in minutes, whereby a calibration line of the test system was obtained. Subsequently, further tests were carried out with different 3,3'-dihydroxyisorenated concentrations in the reaction mixture and the calibration line was used to determine the delay in cumene hydroperoxide formation at different 3,3'-dihydroxyisorenieratin and other antioxidant concentrations in minutes. The reaction delay was measured at 2 x 10 ^-4 mol / l, 4 x 10 ^-4 mol / l, 1 x 10 ^-3 mol / l and 2 x 10 ^-3 mol / l 3,3'-dihydroxyisorenieratin. For each of the measured antioxidant concentrations, the time of complete inhibition of the reaction was determined by calculating the corresponding intercept of the regression line. The calculated inhibition times were then plotted against the respective antioxidant concentration and the associated regression line determined. These lines were used to compare the antioxidant capabilities of the antioxidants. A high slope of the straight line indicates a high antioxidant effect. Antioxidants In descending order Slope / min · l / mol Deviation / min · l / mol Y-section / min Deviation / min Hydroquinone 1.23 · 10 ⁵ 1 · 10 ³ 15.2 1.2 canthaxanthin 1.24 · 10 ⁵ 0.7 · 10 ³ 20.2 0.4 cryptoxanthin 1.30 · 10 ⁵ 0.4 · 10 ³ 17.7 1.2 zeaxanthin 1.54 · 10 ⁵ 2 · 10 ³ 19.9 2.7 Dimethoxyisorenieratene 1.60 · 10 ⁵ 8 · 10 ³ 23.1 8.9 astaxanthin 1.85 · 10 ⁵ 0.5 · 10 ³ 12.7 0.4 3,3'-Dihydroxyisorenieratene 5.74 · 10 ⁵ 50 · 10 ³ -36 64

Example 39

Determination of the antioxidant effect of 3,3'-Dihydroxyisorenieratene in the oxygen partial pressure test.

One Reactive system of 5 ml of cumene with 4 ml of chlorobenzene and 1 ml of 0.45 M solution 2,2'-azobis (2,4-dimehtylvaleronitrile) (AMVN) in Chorobenzen was provided with various antioxidants and exposed to an oxygen partial pressure of 150 Torr. consequently surrendered for the reaction concentrations of 3.6 mol / l cumene and 45 mmol / l AMVN plus variable concentrations of antioxidant. During the course of the reaction was the decrease of the oxygen partial pressure relative to a Reference vessel measured. As a differential pressure transducer was the device MKS Baratron (type 223B) and as absolute pressure transducer the device MKS Baratron (type 122A) is used.

The values were read out by the device MKS Type PDR-D-1 Power Supply Digital Readout Degital. For better comparability, the traces were normalized to the normal pressure of 760 Torr and then the slope of the curve was determined between 50 and 70 minutes and multiplied by the factor 665.7 (M * min) / (s * Torr) to give the slope in oxidation rates (-D [O ₂ ] / dt · 10 ^-8 M / s). A low oxidation rate corresponds to a high antioxidant effect. Concentration antioxidant Oxidation rate / 10 ^-8 mol / l · s cryptoxanthin zeaxanthin Astacantin 3,3'-Dihydroxyisorernieraten 2.00 · 10 ^-3 32.19 19.71 11.94 1.99 1.00 · 10 ^-3 22,62 16.16 11.56 0 4.00 · 10 ^-4 13,60 8.26 8.86 3.22 2.00 · 10 ^-4 16.44 18.67 11.68 2.27 4.00 · 10 ^-5 ... ... ... 5.92 4.00 · 10 ^-5 75.38 71.24 79.32 17.74 2.00 · 10 ^-5 83.88 80.13 87.88 77.39

Example 40

comparison the oxidation rates of various carotenoids and phenolic substances.

A reactive system of 5 ml of cumene with 4 ml of chlorobenzene and 1 ml of 0.45 M solution of 2,2'-azobis (2,4-dimehtylvaleronitrile) (AMVN) in chlorobenzene was provided with various antioxidants and an oxygen partial pressure of 150 Torr exposed. Consequently, the reaction yielded concentrations of 3.6 mol / L cumene and 45 mmol / L AMVN plus antioxidant in a concentration of 2.00 × 10 ^-5 and 4.00 × 10 ^-5, respectively.

During the course of the reaction, the decrease in the oxygen partial pressure relative to a reference vessel was measured. The differential pressure transducer used was the MKS Baratron (type 223B) and the MKS Baratron (type 122A) absolute pressure transducer. The values were read out by the device MKS Type PDR-D-1 Power Supply Digital Readout Degital. For better comparability, the traces were normalized to the normal pressure of 760 Torr and then the slope of the curve was determined between 50 and 70 minutes and multiplied by the factor 665.7 (M * min) / (s * Torr) to give the slope in oxidation rates (-d [O ₂ ] / dt · 10 ^-8 M / s). A low oxidation rate corresponds to a high antioxidant effect.

The abbreviation BHT stands in the table for 4-methyl-2,6-di-tert-butylphenol

The abbreviation BHT carotenoid is shown in the table for 3,3'-dihydroxy-2,2 ', 4,4'-tetra-tert-butylisorenieratin

The abbreviation DHIR is in the table for the 3,3'-Dihydroxyisorenieraten. Oxidation rate / 10 ^-8 mol / l · s Oxidation rate / 10 ^-8 mol / l · s Concentration antioxidant 2.00 · 10 ^-5 4.00 · 10 ^-5 antioxidant alpha-tocopherol 101.7 99.8 resveratrol 87.6 69.8 BHT 108.9 100.2 BHT-carotenoid 93.1 30.8 DHIR 77.4 17.7 DB BHT-carotenoid 98.0 93.7 astaxanthin 102.4 96.2 canthaxanthin 103.0 96.6 cryptoxanthin 96.0 86.0 zeaxanthin 96.9 81.2

Claims (21)

Antioxidant containing at least one isorenieratin compound of the general formula

wherein R ¹ = H or a "readily cleavable protecting group" may be the same or different R ² to R ⁴ and may be a C ₁ to C ₃ alkyl group. Antioxidant, according to claim 1, containing at least an isorenated urine compound (I) wherein R1 = H and R2 to R4 = methyl (3,3'-dihydroxyisorenieratin). Antioxidant containing at least one isorenieratin compound (I) according to claims 1 or 2 and 3,3'-dihydroxyisorenieratin-1-quinone (II) or 3,3'-dihydroxy-2,2 ', 4,4'-tetra-tert-butylisorenieratin-1-quinone (III) or 3,3'-dihydroxy-2,2 ', 4,4'-tetra-tert-butylisorenieratin (IV) or mixtures of these. Mixtures (M1) containing at least one isorenieratin compound (I) according to claims 1 or 2 and 3,3'-dihydroxyisorenieratin-1-quinone (II) or 3,3'-dihydroxy-2,2 ', 4,4'-tetra-tert-butylisorenieratin-1-quinone (III) or mixtures of these. Mixtures (M2) containing 3,3'-dihydroxy-2,2 ', 4,4'-tetra-tert-butylisorenieratin (IV) and at least one Isorenieratin compound (I) according to claims 1 or 2 or a mixture (M1) according to claim 4. Preparations containing at least one isorenieratin compound (I) according to claims 1 or 2 or 3,3'-dihydroxyisorenieratin-1-quinone (II) or 3,3'-dihydroxy-2,2 ', 4,4'-tetra-tert-butylisorenieratin-1-quinone (III) or 3,3'-dihydroxy-2,2 ', 4,4'-tetra-tert-butylisorenieratin (IV) (Compounds V) or mixtures thereof Dermocosmetics, pharmaceuticals, food or feed, containing at least one of the compounds (V) or prepared using at least one preparation according to claim 6th Solids or liquids or mixtures thereof, containing at least one of the compounds (V). dye, containing dihydroxyisorenieratin-1-quinone (II) or 3,3'-dihydroxy-2,2 ', 4,4'-tetra-tert-butylisorenieratin-1-quinone (III) or 3,3'-dihydroxy-2,2 ', 4,4'-tetra-tert-butylisorenieratin (IV) or mixtures (M1) or (M2). dye, containing at least one of the compounds (V) in the form of H or J aggregates. Dermocosmetics, pharmaceuticals, food or feed, containing at least one colorant according to claims 9 or 10th Solids or liquids or mixtures thereof, containing at least one colorant according to claims 9 or 10th Vesicles containing at least one of the compounds (V). Dermocosmetics, pharmaceuticals, food or feed containing vesicles according to claim 13th Solids or liquids or mixtures thereof, containing vesicles according to claim 13th Carotenoid formulations containing at least one of the compounds (V). Preparations containing at least one carotenoid formulation according to claim 16 or prepared using at least one preparation according to claim 6th Dermocosmetics, pharmaceuticals, food or feed, containing at least one carotenoid formulation according to claim 16 or prepared using at least one preparation according to claim 6th Gelatin capsules containing at least one carotenoid formulation according to claim 16 or prepared using at least one carotenoid formulation according to claim 16th Process for the preparation of antioxidants, mixtures (M1) or (M2), coverings, stains, vesicles, carotenoid formulations, Dermocosmetics, pharmaceuticals, food or feed, gelatine capsules or other solids or liquids or mixtures thereof according to at least one of the claims 1 to 19, characterized in that at least one of the compounds (V), antioxidants, mixtures (M1) or (M2), preparations, colorants, Vesicles, or carotenoid formulations, according to any one of claims 1 to 6, 9, 10, 13, 16 or 17 while their production is used. Use of at least one of the compounds (V) or antioxidants, mixtures (M1) or (M2), preparations, dye, Vesicles or carotenoid formulations according to claims 1 to 6, 9, 10, 13, 16 or 17, for the production of antioxidants, mixtures, passages, colorants, Vesicles, carotenoid formulations, dermocosmetics, pharmaceuticals, Food or feed, gelatin capsules or other solids or liquids or mixtures thereof.