DE10046127A1 - Filling device for micro-powder has dosing device with rotary dosing supplied from region of supply chamber with uniform distribution of micro-powder - Google Patents

Abstract

The filling device has a supply chamber (26) for the micro-powder (32) and a dosing device with a rotary dosing roller (16), coated with the micro-powder by transporting it from a region of the supply chamber in which the micro-powder is uniformly distributed, to a dosing container (24) containing the dosing roller. An Independent claim for a filling method for a micro-powder is also included.

Description

TECHNICAL AREA

The invention relates to an apparatus and a method for the filling of microised powder. The single ones Particles of this powder are extremely small; your weight ranges between 5 and 20 micrograms. Such small powdered particles are not flowable what made their handling difficult. Filling Containers with such powder is therefore not technologically simple.

STATE OF THE ART

In the pharmaceutical sector, it is known to produce drugs that consist of microised powder to fill in containers. For dosing a dosing device is used, the one Metering roller, which in turn contains each Packing powder quantity from a powder stockpile Chamber gets allocated. For this there is a in the metering roller Dosing container left out in the corresponding Position of the metering roller the powder is sucked in. Then the metering roller with its powder filled dosing container twisted and that in the Dosing container in the powder in each case emptying the container into it.

PRESENTATION OF THE INVENTION

Based on this prior art the invention is based on the object in the prior art  known possibility of filling with microised powder to improve to ensure that that in repetitive, same steps reproducible, equal amounts of powder in the dosing filled in and accordingly in the respective filling container can be emptied into it.

This invention is for the device according to the invention by the features of claim 1 and for the corresponding Method according to the invention by the features of the orderly claim 24 given. Useful further training of both the device and the method Subject of subclaims.

The invention uses the knowledge that by compression a powder of the powder present in the storage chamber area can be generated in which the powder is spatially is distributed very evenly. This has the advantage that the removal of a certain volume range of powder from this compacted area of a certain weight amount of powder corresponds. If the distribution of Powder cannot be assured of this; in one certain room volume is with uneven distribution of the Powder does not always have the same number of particles Powder included. One is particularly in the pharmaceutical sector exact drug dosage extremely important. Fiction according to the dosing in the dosing roller ratio filled with powder from this powder range, in which the powder is spatially evenly distributed. In the In this way, the dosage container can always do an even amount Powder can be poured into it. So that can in the filling containers with the same amount of powder be emptied.  

The desired compaction in the powder storage container can by means of a stamp pressed into the powder be generated. The one moving into the powder from above Stamp creates one before its free stamp end Pressure cone inside the powder container that leads to a certain compression of the powder in this pressure cone Area leads. This stamp can have a full cross-section have. In this case, it may be appropriate To form a slightly concave front face to make yourself to get a well spreading pressure cone.

According to another embodiment of the invention, this can Stamp can also be designed in the form of a hollow cylinder, with a piston that can be moved back and forth inside.

Alternatively or in addition to the stamp hollow cylinder solution can the stamp or the hollow cylinder or other comparable pressure elements in fast vibrations be transferred. This also makes it possible to build one Pressure cone "in front" of the stamp or hollow cylinder or generate in general in front of the pressure element or improve. These vibrations can go in the direction of Direction of movement of the stamp or Hollow cylinder and / or act in the transverse direction.

Always the same conditions in the powder storage chamber when removing powder into the dosing container can have according to one also shown in the drawing Embodiment of the device two according to the invention Leveling devices may be provided. With a first The surface of the powder chamber is leveled Powder in stock leveled and with a second The leveler below the surface becomes leveler Powder (again) evenly distributed so that the same pressure  and thus distribution ratios within the powder can be generated. The latter means that an im pressure cone created in the previous filling cycle is equalized. Another subsequent one Filling process finds the same output Druckver Ratios within the powder, as they did before previous filling process in the powder. The surface leveler mentioned is preferably in Shape of a slider are formed during the depth Equalizers, on the other hand, are more in the form of a calculation has. The surface leveler mentioned above a constant high amount of powder, i. H. constantly strong Ensure powder layer in the container.

Filling the dosing tank in the dosing roller ratio is preferably through inside the Dosing roller generated negative pressure. The powder will during this suction process from the storage container into the Dosing container sucked in. The dosing container is located when filling in the area of effect of the above mentioned pressure cone and thus in that area of Powder chamber in which the powder is spatially uniform is distributed.

In addition to this suction process can be done by appropriate Adjust the stamp powder from the area where it is is spatially evenly distributed in the dosing container - the sucking in, as it were, supporting - pushed become.

The stamp can also be used as a hollow cylinder inside piston which can be moved back and forth. To the Generating the pressure cone already mentioned above the hollow cylinder with in the area of its free opening piston in the amount of powder from above  pushed so that again in front of its face desired pressure cone and thus an area with spatial can adjust evenly distributed powder. Subsequently can then the hollow cylinder without the piston into the Bottom area of the chamber. The end sharpened jacket area of the hollow cylinder causes Inserting the hollow cylinder into the compressed one Powder area, so that it hardly changed Change of consistency of the powder within the previously generated pressure cone occurs. Inside the hollow cylinder is then an area with evenly distributed powder available. The inside of the hollow cylinder then becomes Powder sucked into the dosing container. In addition can the piston is pushed towards the dosing container become.

After filling the dosing container, the stamp or the hollow cylinder with its piston again pulled out of the powder chamber backwards. Then it can the levelers already mentioned above for one even distribution of the powder in the powder chamber to care.

The bottom of the dosing container is covered by a Filter covering formed, but not permeable to air is permeable to powder. This filter pad is simple Way through an inner lining of the Filter tube representing metering roller realized. The one in Air pressure prevailing inside the filter tube then acts through the filter tube into the dosing container.

The filled dosing container is turned by turning the dosing roller over the container to be filled. This container is particularly useful for packaging  Medicines in the blister of a so-called blister strip. According to the number next to each other of individual blisters of a blister strip are also corresponding several dosing containers in the dosing roller available. Each individual dosage container is preferred a stamp or hollow cylinder with piston assigned.

To empty the blister over the assigned blister located dosing container or over a series of blistering series of dispensers overpressure in the interior of the metering roller generated and thereby in the or in the Dosing containers filled powder from the containers transported out and into the blister. This Overpressure is relatively low to prevent the Blowing out the dosing container also powder from the blister is blown out with.

The metering roller is then rotated further until each Dosing container in front of a fixed waste container is positioned. This can be done by generating overpressure or the dosing containers are blown empty and existing powder residues that are still in the dosing containers should be present or that in the filter tube should be sucked in, blown out and with it be removed. These powder residues can be removed using suction pressure sucked out of the waste container or containers and thereby be removed from the device. Then then the metering roller is turned back to its original position, in the one or more dosing containers back to the floor area are adjacent to the powder chamber.  

Blister strips are preferably made of plastic material. Also the plastic flat material web with which the filled blister are preferably there made of plastic. This is used for tight locking Plastic sheet on the filled blister strips welded. To the influence of when welding the Blister strips appearing heat load on medicinal To keep powder as low as possible and to avoid heat peaks avoid, it is recommended to use the blister strip with continuous speed through the welding station, in which the blister strips are sealed transport. As a rule, this leads to the fact that preferably also in the area of the filling device open blister strips with constant transport speed is moved. The transport movement of the blister following the metering roller during the Emptying your dosing container preferably Continue to turn. The emptying then takes place within one Angular range of the metering roller instead. Because the distance of the Blister within a blister strip is smaller than that Diameter of the metering roller are used for filling preferably several metering rollers, with their axes of rotation aligned parallel, at a distance in the direction of transport be arranged side by side. That way, by corresponding cooperation of the different Dosing rollers with all blisters of a blister strip micro-filled powder and then through Welding a plastic sheet to be closed, too at very high transport speed in relation to Working cycle duration of the metering rollers.

Further refinements and advantages of the invention are the in the claims further listed features and in the embodiments shown in the drawing remove.  

BRIEF DESCRIPTION OF THE DRAWING

The invention is described below with reference to the drawing illustrated embodiments described in more detail and explained. Show it:

Fig. 1 shows a cross section through a Verfüll device according to the invention, with their metering in its starting position,

Fig. 2 is a view similar to Fig. 1, with lowered into the powder chamber stamp,

Fig. 3 is a view similar to Fig. 2, with a retracted out of the powder chamber punch and completely filled in the metering Dosierbehältnis,

Fig. 4 is a view similar to Fig. 3, with a slightly twisted metering roller and with a moving depth equalizer,

FIG. 5 shows a representation similar to that of FIG. 4, with a further rotated metering roller and a further depth leveler, FIG.

Fig. 6 is a view similar to Fig. 5, with the metering roller in its emptying position and with which situated in the backward movement depth equalizer, and in addition a moving surface leveling agents,

Fig. 7 is a view similar to Fig. 6, with a metering whose Dosierbehältnis is located in the region of a residue container, and with a back located in its starting position and a depth equalizer again zurückbe lanes surfaces-leveling agent,

Fig. 8 is a, in the direction of its initial position further rotating metering roll and a moving back into its initial position surface leveling agents

Fig. 9 is a in the form of a hollow cylinder with pistons formed stamp according to the invention, during its immersion in the powder chamber and generating a pressure below its cone cylinder and piston end,

Fig. 10 shows a representation according to FIG. 9, vorbewegtem with it into the bottom region of the powder chamber hollow cylinder,

FIG. 11 shows a representation similar to that of FIG. 10, with the piston advancing further in the direction of the metering container within the hollow cylinder, and.

Fig. 12 is a representation similar to that of Fig. 11 with a hollow cylinder moving back again together with its piston located inside.

WAYS OF CARRYING OUT THE INVENTION

A filling device 10 for microized powder has a metering roller 16 which is rotatably mounted in a portal 12 about an axis of rotation 14 ( FIG. 1). The metering roller 16 has a hollow interior 18 which is enveloped by a solid tubular jacket 20 .

A filter tube 22 is provided on the inside of the tube jacket 20 . The filter tube 22 forms an inner lining of the tube jacket 20 . This filter tube 22 is so fine-pored that it is permeable to air but not permeable to the microized powder to be filled by the filling device 10 .

The interior 18 , which is hollow in the present example, can be partially filled by packing in order to reduce the volume of the interior 18 within the metering roller 16 and thus to set the pressure and vacuum conditions desired in the interior 18 during the filling process in an economically advantageous manner can.

In the position of the metering roller 16 shown in FIG. 1, the tubular jacket 20 has a recess at the top which forms a metering container 24 for the microized powder. In the present example, several of these Dosierbe ratios 24 are present in series one behind the other, as will be described in more detail below in connection with the filling.

Above the metering roller 16 there is a powder chamber 26 with an opening 28 formed in the area of the metering container 24 in its bottom area 30 . In this chamber 26 there is in each case a predetermined amount of micro-powder 32 , from which the metering container or containers 24 can be filled in the position of the metering roller 16 shown in FIG. 1.

In the powder chamber 26 - in the illustration according to FIG. 1 - there is a depth leveler 34 on the right side and a surface leveler 36 on the left side.

The depth leveler 34 has a rake 38 which is fastened to a linkage 40 and which can be pushed back and forth in the transverse direction 42 by the powder 32 located in the chamber 26 . For this purpose, a motor device (not shown in the drawing) engages the linkage 40 . With the aid of this rake 38 , which moves back and forth in the transverse direction 42 , a layer formation below the surface 44 of the powder 32 can be destroyed and the powder as a whole can thereby be leveled.

The surface leveler 26 has a slide 46 which can also be pushed back and forth in the transverse direction 42 over the surface 44 of the powder 32 . For this purpose, the slide 46 is seated on a linkage 48 which can be moved accordingly via a motor device, not shown in the drawing. With the help of the surface leveler 36 , the amount of powder present in the chamber 26 and thus the height 50 of the powder 32 can be kept constant.

With the depth leveler 34 , a layer formation or a regionally unevenly strong compression of the powder 32 within the chamber 26 can be nullified and thus the powder can be leveled "depth-wise" in the region of its height 50 .

So much powder is poured into the powder chamber 26 from a powder container 54 positioned above the powder chamber 26 that the powder height 50 shown in FIG. 1 is set in the chamber 26 .

A stamp 60 is positioned above the powder chamber 26 , in the present case exactly opposite the metering container 24 in terms of height. This stamp 60 is fixedly attached to a holder 62 and can be moved in its longitudinal direction, ie in direction 64 . The stamp 60 can thus be lowered into the powder chamber 26 and thus into the powder 32 .

Below the metering roller 16 , a blister strip 70 is shown, which is transported past in the transport direction 72 on the underside of the metering roller 16 at a constant speed in the present example. Rows of individual blisters 74 are formed in the blister strip 70 and are filled with powder from the powder chamber 26 by means of the metering roller 16 in a manner which will be described in more detail below.

On the outside of the filter tube 22 and thus the metering roller 16 , a residual container 78 is connected via a connecting channel 76 . The connecting channel 76 is gas and powder-tight on the outside of the filter tube 22 .

If a dosing container 24 is mentioned in the foregoing, this also means in the same way a number of dosing containers 24 which are present in series in the filter tube 22 . In the same way, there are a corresponding number of residues containers 78 or a single residues container 78 in the form of a tube which, via a corresponding number of connecting channels 76 , the number of which corresponds to the number of metering containers 24 , abuts the tube jacket 20 from the outside.

The filling process is described in connection with FIGS . 2 to 6 in successive process steps.

The plunger 60 is moved downward into the powder 32 from its position according to FIG. 1. This immersion is preferably carried out in a first step as far as can be seen in FIG. 9, which is also described in connection with another stamp design. During this immersion, a pressure cone 82 forms below the end face 80 of the stamp 60 . The powder 32 has assumed a uniform distribution within the pressure cone 82 due to its forced compression. The powder within this pressure cone 82 is given the reference symbol 32.1 . During the immersion of the stamp 60, the surface leveler 36 and the depth leveler 34 remain in their respective starting positions.

By further immersing the stamp 60, the front face 80 of the punch 60 comes to its in Fig. 2 lower position shown in the opening 28 located in the bottom area 30 of chamber 26. By activating a negative pressure in the interior 18 of the metering roller 16 , powder 32.1 is sucked into the metering container 24 from the pressure cone area 82 . At the same time, the plunger 60 moved downwards can push powder 32.1 from the area of the pressure cone 82 into the dosing container 24 . The suction by means of the negative pressure within the metering roller 16 and the feeding of powder 32.1 from the area of the pressure cone 82 can take place in parallel or with a time delay. However, it is also possible to just suck in powder and leave the stamp 60 in the position shown in FIG. 9 during the filling process.

After the end of the filling process of powder into the dosing container 24 , the plunger 60 is pulled back upwards out of the area of the powder chamber 26 ( FIG. 3). In the present example, when sucking in, some powder 32.2 has been sucked into the filter tube 22 , as shown in FIG. 3.

The metering roller 16 is now rotated counterclockwise about its axis of rotation 14 ( FIG. 4). After leaving its position shown in FIGS. 1 to 3, the depth leveler 34 is activated. His rake 38 thereby moves in the transverse direction 42 to the left. Generally, the rake 38 will push a small bow wave 84 of powder in front of it. When the powder 32 and the powder 32.1 are plowed through, the compressed area of the powder 32.1 is destroyed, so that in total only powder with a consistency 32 is present in the chamber 26 ( FIGS. 7, 8).

During its movement to the left ( FIG. 4), only the depth leveler 34 is moved, the left surface leveler 36 remains in its starting position shown.

Fig. 5 shows the continuation of the procedure. The right depth leveler 34 has almost reached its left end position and, as FIG. 6 subsequently shows, begins its backward movement in the transverse direction 42 to the right. Now, when the depth leveler 34 moves back, the left surface leveler 36 can also move in the transverse direction 42 , also to the right. The surface leveler 36 again creates a constant height 50 of powder 32 within the powder chamber 26 .

During the back and forth movement of the levelers 34 , 36 , the metering roller 16 has moved into its emptying position shown in FIG. 6. In this emptying position, the dosing container 24 is in its lower position. It should be repeated once again that, instead of the one metering container 24, in the same way several metering containers 24 arranged in a row along the metering roller 16 can generally be present. Emptying can also take place with the metering roller 16 rotating.

In the situation shown in FIG. 6, an overpressure is now generated in the interior 18 of the metering roller 16 . With the help of the overpressure, the powder 32.1 located in the metering container 24 is filled into an empty blister 74 positioned below the container 24 . The number of dosing containers 24 corresponds to the number of blisters 74 positioned in a row below the dosing roller 16 .

After the dosing container 24 has been emptied, the dosing roller 16 is rotated further until the dosing container 24 has come into the area in front of the connecting channel 76 ( FIG. 7). By now generating an excess pressure which is very strong compared to the previous positive pressure, any powder 32.1 still present in the container 24 is blown through the connecting channel 76 into a residual container 78 connected to the connecting channel 76 . This empty blowing of the dosing container 24 by means of excess pressure present in the interior 18 can be supported by suctioning off the connecting channel 76 or the remaining container 78 . During this empty blowing of the proportion 24 , the powder 32.2 located in the area of the filter tube 22 is also removed. This ensures a long service life for the filter tube 22 .

In the process state shown in FIG. 7, the right depth leveler 34 is again in its right starting position. The left surface leveler 36 is on its way back to its starting position shown in FIG. 4. Starting position shown in its backward movement. In its backward movement, the surface leveler 36 pushes a bow wave 86 of powder 32 in front of it. The bow wave 86 becomes smaller and smaller as it moves and will practically no longer exist in its initial position shown in FIG. 4.

FIG. 8 shows a process state in which the metering roller 16 continues to rotate in the direction of its starting position shown in FIG. 1.

Then a new filling process of the dosing container or containers 24 can take place again and a new row of empty blisters 74 can be filled accordingly.

The “stamp” shown in FIG. 9 is a hollow cylinder 90 which is closed at the end by a piston 92 on the end. The piston 92 is adjustable on a piston rod 94 in the direction 64 within the hollow cylinder 90 . When immersed in its position shown in FIG. 9, the piston 92 generates a pressure cone 82 beneath it. Within the pressure cone 82 , the powder 32 has assumed its evenly distributed, slightly compressed form 32.1 . Below the pressure cone 82 there is again, as also described above in connection with the stamp 60 , a metering container 24 which is closed at the bottom by the air-permeable but powder-tight filter tube 22 .

As soon as the pressure cone 82 has built up, the hollow cylinder 90 is moved further down. Its sharpened end wall 96 cuts into the pressure cone 82 and causes practically no further compression or pressing of powder 32.1 into the container 24 . Inside the hollow cylinder 90 , below the piston 92 , there is an area of the pressure cone 82 and thus powder 32.1 in a uniformly distributed form. From this inner space 98 , powder 32.1 is now sucked into the dosing container 24 by generating a negative pressure in the inner space 18 of the metering roller 16 , as has already been described above in connection with FIGS. 1 to 8. It is possible, as shown in FIG. 11, to move the piston 92 downward when this powder 32.1 is sucked into the metering container 24 , until, as shown by way of example in FIG. 11, something into the area of the metering container 24 ,

Subsequently ( FIG. 12), the hollow cylinder 90 is then pulled backwards with its piston 92 (arrows 99 ) from the powder 32 or 32.1 and thus from the powder chamber 26 . Leveling of the powder 32 and 32.1 then follows, as described above by way of example.

The method of the stamp 60 or of the hollow cylinder 90 and its piston 92 produces reproducible conditions above the metering container 24 . The powder 32.1 located there is evenly distributed in the area above the metering container 24 , regardless of how it is distributed in the remaining area of the chamber 26 . With the aid of the device according to the invention and the method according to the invention, equally large quantities of powder can be filled into the metering container 24 one after the other. In this way, a uniform filling of the blister strip 70 is possible.

Claims (27)

1. Device for filling micro-powder, with a powder ( 32 ) in stock chamber ( 26 ) and from this chamber ( 26 ) to be fed with powder, rotating metering roller ( 16 ) containing metering device, characterized in that
a device for generating a powder region ( 82 ) in the powder chamber ( 26 ), in which the powder ( 32.1 ) is spatially uniformly distributed, and
there is a device for transporting powder ( 32.1 ) from this powder area ( 82 ) into the metering container ( 24 ) present in the metering roller ( 16 ). 2. Device according to claim 1, characterized in that a stamp ( 60 ) in the powder area ( 82 ) located powder ( 32.1 ) is designed to be immersible by a predetermined amount and for a predetermined period of time. 3. Device according to claim 2, characterized in that the stamp ( 60 ) has an at least slightly concave curved end face ( 80 ). 4. The device according to claim 1, characterized in that a hollow cylinder ( 90 ) with pistons ( 92 ) which can be moved back and forth in its interior ( 98 ) into the powder ( 32.1 ) located in the powder region ( 82 ) by a predetermined amount and for a predeterminable period of time is designed to be immersible. 5. The device according to claim 4, characterized in that the piston ( 92 ) can be moved out of the hollow cylinder ( 90 ). 6. Device according to one of claims 2 to 5, characterized in that the stamp ( 60 ) or the hollow cylinder ( 90 ) can be set in vibration. 7. The device according to claim 6, characterized in that the vibrations in the direction of the adjustability ( 64 ) of the plunger ( 60 ) or the hollow cylinder ( 90 ) and / or in the transverse direction ( 42 ) can be generated. 8. Device according to one of the preceding claims, characterized in that a device ( 36 ) for leveling the surface ( 44 ) of the powder ( 32 ) located in the powder chamber ( 26 ) is present. 9. Device according to one of the preceding claims, characterized in that a device ( 34 ) for leveling the density of the powder ( 32 ) located in the powder chamber ( 26 ) is present. 10. The device according to claim 8, characterized in that the device ( 36 ) for leveling the surface ( 44 ) of the powder contains a slide ( 46 ) which is at a predetermined, constant height ( 50 ) of the chamber ( 26 ) in this chamber ( 26 ) is movable back and forth. 11. The device according to claim 9, characterized in that the device ( 34 ) for leveling the density of the powder contains a rake ( 34 ) through the powder ( 32 ) located in the chamber ( 26 ) and thus also through the area ( 82 ) can be moved back and forth with the spatially uniformly distributed powder ( 32.1 ). 12. Device according to one of the preceding claims, characterized in that on the inside of the metering roller ( 16 ) there is an air-permeable filter tube ( 32 ) that forms a tight barrier for the powder ( 32 ). 13. Device according to one of the preceding claims, characterized in that a waste container ( 76 , 78 ) is gas and airtight on the outside of the rotatable metering roller ( 16 ). 14) Device according to claim 13, characterized in that a device for generating a negative pressure is connected to the residue container ( 76 , 78 ). 15. Device according to one of the preceding claims, characterized in that a device for selectively generating an overpressure or underpressure in the interior ( 18 ) of the metering roller ( 16 ) is present. 16. Device according to one of the preceding claims, characterized in that a device for transporting the container ( 74 ) to be filled from the metering roller ( 16 ) with powder ( 32 ) past the metering roller ( 16 ) is provided. 17. The apparatus according to claim 16, characterized in that the containers ( 74 ) are the blisters of at least one blister strip ( 70 ). 18. The apparatus of claim 16 or 17, characterized in that the or the blister strips ( 70 ) at a constant speed ( 72 ) on the metering roller ( 16 ) can be protested. 19. The device according to any one of claims 16 to 18, characterized in that a plurality of metering rollers ( 16 ) with their axes of rotation ( 14 ) are arranged side by side in a parallel alignment, the spacing between adjacent individual blisters ( 74 ) in the transport direction ( 72 ) is smaller than the distance between the axes of rotation ( 14 ) of adjacent metering rollers ( 16 ). 20. Device according to one of the preceding claims, characterized in that it is followed by a closing device for the containers ( 74 ) filled with powder ( 32 ), such as in particular for the blisters ( 74 ), in the transport direction ( 72 ). 21. The apparatus according to claim 20, characterized in that
the containers ( 74 ), in particular the blisters, consist of plastic,
the filled containers ( 74 ) can be closed by a weldable flat material web made of plastic. 22. The apparatus according to claim 21, characterized in that the welding of the flat material web continuously, and thus more constant relative to each other Speed between closing device and Flat material web, is feasible. 23. Device according to one of the preceding claims, characterized in that the plunger ( 60 ) or the piston ( 92 ) of the hollow cylinder ( 90 ) is adjustable into the metering container ( 24 ) of the metering roller ( 16 ). 24. A method for filling micro-powder with a filling device according to one of the preceding claims, characterized in that
the plunger ( 60 ) or the hollow cylinder ( 90 ) is immersed in the powder ( 32 ) located in the powder chamber ( 26 ) in a first direction of movement, so that a pressure cone area ( 82 ) is located in front of the free end of the plunger ( 60 ) forms within which the powder ( 32 ) assumes a spatially constant distribution ( 32.1 ),
the metering roller ( 16 ) is rotated in such a rotational orientation that its metering container ( 24 ) is located in the area of this pressure cone area ( 82 ),
a suction vacuum is then generated inside ( 18 ) of the metering roller ( 16 ) and a certain amount of powder ( 32.1 ) is sucked into the metering container ( 24 ) from this pressure cone area ( 82 ) located in front of the metering container,
the metering roller ( 16 ) is then rotated about its axis of rotation ( 14 ) until the metering container ( 24 ) is in front of a container ( 74 ) to be filled,
an overpressure is then generated in the interior ( 18 ) of the metering roller ( 16 ) and the powder ( 32.1 ) in the metering container ( 24 ) is thereby brought into the container ( 74 ),
the rotary roller ( 16 ) is then rotated about its axis of rotation ( 14 ) until its metering container ( 24 ) is in front of the waste container ( 76 , 78 ),
an overpressure is then generated inside the metering roller ( 16 ) and air is blown through the emptied metering container ( 24 ),
the metering roller ( 16 ) is then rotated about its axis of rotation ( 14 ) until its metering container ( 24 ) is again within a pressure cone area ( 82 ) that is newly created or is still to be created. 25. The method according to claim 24, characterized in that
after the dosing container ( 24 ) has been filled, the punch ( 60 ) or the hollow cylinder ( 90 ) is withdrawn from the powder ( 32 , 32.1 ),
then the rake ( 38 ) is moved through the powder ( 32 , 32.1 ) in a first direction,
then the rake ( 38 ) is moved back in a second direction through the powder ( 32 , 32.1 ) and
the slider ( 46 ) is moved along the surface ( 44 ) of the powder ( 32 ) and then moved back again. 26. The method according to claim 24 or 25, characterized in that
the piston (92) of the hollow cylinder (90) when inserting dipped into the powder (32) first of all with respect to the hollow cylinder (90) does not move,
the hollow cylinder ( 90 ) is then immersed further into the bottom area ( 30 ) of the chamber ( 26 ) and is guided into the pressure cone area ( 82 ) formed or through this pressure cone area ( 82 ). 27) The method of claim 26, characterized in that the piston located in the hollow cylinder (90) (92) is advanced towards the end of the hollow cylinder (90), while this end of the hollow cylinder in the base region (30) the chamber ( 26 ), in front of the metering container ( 24 ).