CY2016005I1 - Αλκαλικη φωσφαταση στοχευμενη στα οστα, κιτ και μεθοδοι χρησης αυτων - Google Patents

Αλκαλικη φωσφαταση στοχευμενη στα οστα, κιτ και μεθοδοι χρησης αυτων

Info

Publication number: CY2016005I1
Authority: CY; Cyprus
Prior art keywords: kits; bone; methods; alkaline phosphatase; targeted alkaline
Prior art date: 2007-05-11

Application number

CY2016005C

Other languages

English (en)

Other versions

CY2016005I2 (el

Original Assignee

Alexion Pharmaceuticals, Inc.

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2007-05-11

Filing date

2016-02-23

Publication date

2016-08-31

2016-02-23 Application filed by Alexion Pharmaceuticals, Inc. filed Critical Alexion Pharmaceuticals, Inc.

2016-08-31 Publication of CY2016005I1 publication Critical patent/CY2016005I1/el

2016-08-31 Publication of CY2016005I2 publication Critical patent/CY2016005I2/el

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y301/00—Hydrolases acting on ester bonds (3.1)
- C12Y301/03—Phosphoric monoester hydrolases (3.1.3)
- C12Y301/03001—Alkaline phosphatase (3.1.3.1)
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/33—Fusion polypeptide fusions for targeting to specific cell types, e.g. tissue specific targeting, targeting of a bacterial subspecies
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2799/00—Uses of viruses
- C12N2799/02—Uses of viruses as vector
- C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
- C12N2799/025—Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from a parvovirus

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
General Health & Medical Sciences (AREA)
Wood Science & Technology (AREA)
Zoology (AREA)
Genetics & Genomics (AREA)
Medicinal Chemistry (AREA)
General Engineering & Computer Science (AREA)
Biochemistry (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Physical Education & Sports Medicine (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Molecular Biology (AREA)
Microbiology (AREA)
Biotechnology (AREA)
Biomedical Technology (AREA)
Rheumatology (AREA)
Orthopedic Medicine & Surgery (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Peptides Or Proteins (AREA)
Materials For Medical Uses (AREA)
Enzymes And Modification Thereof (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Adornments (AREA)
Cereal-Derived Products (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Immobilizing And Processing Of Enzymes And Microorganisms (AREA)

CY2016005C 2007-05-11 2016-02-23 Αλκαλικη φωσφαταση στοχευμενη στα οστα, κιτ και μεθοδοι χρησης αυτων CY2016005I2 (el)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US91758907P	2007-05-11	2007-05-11
EP08757088A EP2158319B1 (en)	2007-05-11	2008-05-12	Bone targeted alkaline phosphatase, kits and methods of use thereof

Publications (2)

Publication Number	Publication Date
CY2016005I1 true CY2016005I1 (el)	2016-08-31
CY2016005I2 CY2016005I2 (el)	2016-08-31

Family

ID=40001639

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
CY2016005C CY2016005I2 (el)	2007-05-11	2016-02-23	Αλκαλικη φωσφαταση στοχευμενη στα οστα, κιτ και μεθοδοι χρησης αυτων

Country Status (25)

Country	Link
US (1)	US20100297119A1 (el)
EP (3)	EP2158319B1 (el)
JP (1)	JP5732603B2 (el)
AT (1)	ATE536413T1 (el)
AU (1)	AU2008250945B2 (el)
BR (2)	BR122019000505B1 (el)
CA (1)	CA2687001C (el)
CY (1)	CY2016005I2 (el)
DE (1)	DE202008018131U1 (el)
DK (3)	DK2158319T3 (el)
ES (3)	ES2380546T3 (el)
HK (3)	HK1141047A1 (el)
HR (1)	HRP20140416T1 (el)
HU (2)	HUE031655T2 (el)
IL (1)	IL202057A0 (el)
LT (1)	LTC2368999I2 (el)
LU (1)	LU92976I2 (el)
ME (1)	ME01828B (el)
NL (1)	NL300798I2 (el)
NO (1)	NO2016002I2 (el)
PL (3)	PL2158319T4 (el)
PT (3)	PT2368999E (el)
RS (1)	RS53302B (el)
SI (2)	SI2662448T1 (el)
WO (1)	WO2008138131A1 (el)

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WO2005103263A1 (en)	2004-04-21	2005-11-03	Enobia Pharma Inc.	Bone delivery conjugates and method of using same to target proteins to bone
US20070081984A1 (en)	2005-10-11	2007-04-12	Shunji Tomatsu	Compositions and methods for treating hypophosphatasia
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SI2185589T1 (sl)	2007-06-01	2016-04-29	University Of Maryland Baltimore	Vezavna sredstva za Fc receptor konstantne regije imunoglobulina
US8846603B2 (en)	2010-03-12	2014-09-30	Synageva Biopharma Corp.	NPP1 fusion proteins
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CN105820256A (zh)	2010-07-28	2016-08-03	格利克尼克股份有限公司	天然人蛋白片段的融合蛋白以产生有序多聚化免疫球蛋白fc组合物
CA2823066A1 (en)	2010-12-27	2012-07-05	Alexion Pharma International Sarl	Compositions comprising natriuretic peptides and methods of use thereof
WO2013058833A1 (en) *	2011-10-19	2013-04-25	Enobia Canada Limited Partnership	Compositions comprising alkaline phosphatase and/or natriuretic peptide and methods of use thereof
US10052366B2 (en)	2012-05-21	2018-08-21	Alexion Pharmaceuticsl, Inc.	Compositions comprising alkaline phosphatase and/or natriuretic peptide and methods of use thereof
KR20150058236A (ko)	2012-08-20	2015-05-28	글리크닉 인코포레이티드	항원 결합 및 다가 fc 감마 수용체 결합 활성을 가진 분자
CN106164262B (zh) *	2014-01-24	2020-08-07	安-法玛公司	嵌合型碱性磷酸酶样蛋白
WO2016007873A1 (en) *	2014-07-11	2016-01-14	The Regents Of The University Of Michigan	Compositions and methods for treating craniosynostosis
US10449236B2 (en)	2014-12-05	2019-10-22	Alexion Pharmaceuticals, Inc.	Treating seizure with recombinant alkaline phosphatase
AU2016211447B2 (en)	2015-01-28	2021-09-23	Alexion Pharmaceuticals, Inc.	Methods of treating a subject with an alkaline phosphatase deficiency
PT3325011T (pt)	2015-07-24	2021-01-27	Gliknik Inc	Proteínas de fusão de fragmentos de proteína humana para criar composições de fc de imunoglobulina multimerizadas ordenadamente com ligação a complemento melhorada
CA2993358A1 (en) *	2015-08-17	2017-02-23	Alexion Pharmaceuticals, Inc.	Manufacturing of alkaline phosphatases
WO2017058822A1 (en) *	2015-09-28	2017-04-06	Alexion Pharmaceuticals, Inc.	Identifying effective dosage regimens for tissue non-specific alkaline phosphatase (tnsalp)-enzyme replacement therapy of hypophosphatasia
WO2017074466A1 (en)	2015-10-30	2017-05-04	Alexion Pharmaceuticals, Inc.	Methods for treating craniosynostosis in a patient
US11065306B2 (en) *	2016-03-08	2021-07-20	Alexion Pharmaceuticals, Inc.	Methods for treating hypophosphatasia in children
WO2017171871A1 (en) *	2016-04-01	2017-10-05	Alexion Pharmaceuticals, Inc.	Methods for treating hypophosphatasia in adolescents and adults
JP2019513711A (ja) *	2016-04-01	2019-05-30	アレクシオンファーマシューティカルズ，インコーポレイテッド	アルカリホスファターゼによって筋力低下を治療すること
WO2017173395A1 (en) *	2016-04-01	2017-10-05	Alexion Pharmaceuticals, Inc.	Methods for treating hypophosphatasia in adolescents and adults
US10988744B2 (en)	2016-06-06	2021-04-27	Alexion Pharmaceuticals, Inc.	Method of producing alkaline phosphatase
WO2017214321A1 (en)	2016-06-07	2017-12-14	Gliknik Inc.	Cysteine-optimized stradomers
WO2018004517A1 (en)	2016-06-27	2018-01-04	Alexion Pharmaceuticals, Inc.	Methods for treating hypophosphatasia in children and adolescents
JP7018933B2 (ja)	2016-08-18	2022-02-14	アレクシオンファーマシューティカルズ，インコーポレイテッド	気管気管支軟化症の治療方法
JP2020500871A (ja) *	2016-11-30	2020-01-16	パーデューリサーチファウンデーション	副甲状腺ホルモン受容体刺激を介する、骨折をターゲティングした骨再生
MX2019006573A (es)	2016-12-09	2019-11-18	Gliknik Inc	Optimizacion de fabricacion de gl-2045 un stradomer multimerizante.
WO2018164995A1 (en) *	2017-03-09	2018-09-13	Alexion Pharmaceuticals, Inc .	Glycoprotein manufacturing process
EP3600383A4 (en)	2017-03-31	2020-10-28	Alexion Pharmaceuticals, Inc.	METHODS FOR TREATMENT OF HYPOPHOSPHATASIA (HPP) IN ADULTS AND ADOLESCENTS
CA3096821A1 (en)	2017-09-27	2019-04-04	Inozyme Pharma, Inc.	Methods of improving cardiovascular function and treating cardiovascular disease using a recombinant ectonucleotide pyrophosphatase phosphodiesterase (npp1)
WO2019139891A1 (en)	2018-01-09	2019-07-18	Synthetic Biologics, Inc.	Alkaline phosphatase agents for treatment of neurodevelopmental disorders
JP7214962B2 (ja) *	2018-01-17	2023-01-31	東ソー株式会社	アルカリホスファターゼ高発現動物細胞
WO2019183209A1 (en)	2018-03-20	2019-09-26	Synthetic Biologics, Inc.	Alkaline phosphatase agents for treatment of radiation disorders
EP3768302A4 (en)	2018-03-20	2021-12-15	Synthetic Biologics, Inc.	INTESTINAL ALKALINE PHOSPHATASE FORMULATIONS
EP3773684A1 (en) *	2018-03-30	2021-02-17	Alexion Pharmaceuticals, Inc.	Manufacturing of glycoproteins
CN110499285A (zh) *	2018-05-17	2019-11-26	西安组织工程与再生医学研究所	Alpl基因在制备预防和/或治疗低碱性磷酸酶症的产品中的应用
WO2021119218A1 (en) *	2019-12-09	2021-06-17	Alexion Pharmaceuticals, Inc.	Alkaline phosphatase polypeptides and methods of use thereof
EP4203989A2 (en) *	2020-09-03	2023-07-05	Rampart Bioscience, Inc.	Soluble alkaline phosphatase constructs and expression vectors including a polynucleotide encoding for soluble alkaline phosphatase constructs
KR102571967B1 (ko) *	2021-01-21	2023-08-30	주식회사 마라나노텍코리아	Alp 측정용 바이오 센서
US12083169B2 (en)	2021-02-12	2024-09-10	Alexion Pharmaceuticals, Inc.	Alkaline phosphatase polypeptides and methods of use thereof
WO2024050464A2 (en) *	2022-08-31	2024-03-07	University Of Utah Research Foundation	Gja1-20k compositions and methods for mitigating ischemia-reperfusion injury

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2008
- 2008-05-12 CA CA2687001A patent/CA2687001C/en active Active
- 2008-05-12 ES ES08757088T patent/ES2380546T3/es active Active
- 2008-05-12 ES ES11004496.3T patent/ES2471915T3/es active Active
- 2008-05-12 PT PT110044963T patent/PT2368999E/pt unknown
- 2008-05-12 PT PT130023278T patent/PT2662448T/pt unknown
- 2008-05-12 EP EP08757088A patent/EP2158319B1/en active Active
- 2008-05-12 DK DK08757088.3T patent/DK2158319T3/da active
- 2008-05-12 EP EP11004496.3A patent/EP2368999B1/en active Active
- 2008-05-12 EP EP13002327.8A patent/EP2662448B1/en active Active
- 2008-05-12 AT AT08757088T patent/ATE536413T1/de active
- 2008-05-12 US US12/599,679 patent/US20100297119A1/en not_active Abandoned
- 2008-05-12 PL PL08757088T patent/PL2158319T4/pl unknown
- 2008-05-12 SI SI200831780A patent/SI2662448T1/sl unknown
- 2008-05-12 BR BR122019000505-2A patent/BR122019000505B1/pt active Search and Examination
- 2008-05-12 RS RS20140237A patent/RS53302B/en unknown
- 2008-05-12 PT PT08757088T patent/PT2158319E/pt unknown
- 2008-05-12 JP JP2010507770A patent/JP5732603B2/ja active Active
- 2008-05-12 BR BRPI0811198A patent/BRPI0811198B8/pt active IP Right Grant
- 2008-05-12 PL PL11004496T patent/PL2368999T3/pl unknown
- 2008-05-12 ME MEP-2014-48A patent/ME01828B/me unknown
- 2008-05-12 DK DK11004496.3T patent/DK2368999T3/da active
- 2008-05-12 WO PCT/CA2008/000923 patent/WO2008138131A1/en active Application Filing
- 2008-05-12 DK DK13002327.8T patent/DK2662448T3/en active
- 2008-05-12 PL PL13002327T patent/PL2662448T3/pl unknown
- 2008-05-12 DE DE202008018131U patent/DE202008018131U1/de not_active Expired - Lifetime
- 2008-05-12 HU HUE13002327A patent/HUE031655T2/hu unknown
- 2008-05-12 AU AU2008250945A patent/AU2008250945B2/en active Active
- 2008-05-12 SI SI200831200T patent/SI2368999T1/sl unknown
- 2008-05-12 ES ES13002327T patent/ES2619332T3/es active Active
2009
- 2009-11-11 IL IL202057A patent/IL202057A0/en unknown
2010
- 2010-08-03 HK HK10107384.7A patent/HK1141047A1/xx unknown
- 2010-08-03 HK HK12102957.3A patent/HK1162589A1/xx unknown
2014
- 2014-05-08 HR HRP20140416AT patent/HRP20140416T1/hr unknown
- 2014-05-13 HK HK14104506.3A patent/HK1191372A1/zh unknown
2016
- 2016-01-15 HU HUS1600005C patent/HUS1600005I1/hu unknown
- 2016-01-28 LT LTPA2016004C patent/LTC2368999I2/lt unknown
- 2016-02-02 NO NO2016002C patent/NO2016002I2/no not_active IP Right Cessation
- 2016-02-10 LU LU92976C patent/LU92976I2/xx unknown
- 2016-02-23 CY CY2016005C patent/CY2016005I2/el unknown
- 2016-02-26 NL NL300798C patent/NL300798I2/nl unknown

Also Published As

Publication number	Publication date
PT2158319E (pt)	2012-03-06
WO2008138131A4 (en)	2008-12-31
PL2158319T4 (pl)	2016-04-29
JP2010526543A (ja)	2010-08-05
SI2368999T1 (sl)	2014-07-31
DK2662448T3 (en)	2017-03-20
BRPI0811198A8 (pt)	2018-07-31
AU2008250945B2 (en)	2013-12-12
PT2368999E (pt)	2014-05-26
SI2662448T1 (sl)	2017-05-31
RS53302B (en)	2014-08-29
HUS1600005I1 (hu)	2016-02-29
PL2158319T3 (pl)	2012-05-31
CA2687001C (en)	2019-02-12
EP2368999A1 (en)	2011-09-28
HK1191372A1 (zh)	2014-07-25
JP5732603B2 (ja)	2015-06-10
HK1141047A1 (en)	2010-10-29
LTC2368999I2 (lt)	2017-09-25
AU2008250945A2 (en)	2009-12-24
AU2008250945A1 (en)	2008-11-20
ES2619332T3 (es)	2017-06-26
CA2687001A1 (en)	2008-11-20
IL202057A0 (en)	2011-08-01
DK2158319T3 (da)	2012-03-19
BRPI0811198B1 (pt)	2021-03-09
EP2368999B1 (en)	2014-03-12
ES2471915T3 (es)	2014-06-27
EP2158319A1 (en)	2010-03-03
LTPA2016004I1 (lt)	2016-02-25
BR122019000505A2 (pt)	2021-12-14
LU92976I2 (en)	2016-04-11
HK1162589A1 (en)	2012-08-31
BRPI0811198A2 (pt)	2014-10-21
WO2008138131A1 (en)	2008-11-20
BRPI0811198B8 (pt)	2021-05-25
ME01828B (me)	2014-12-20
DK2368999T3 (da)	2014-05-26
NO2016002I1 (el)	2016-02-02
PT2662448T (pt)	2017-03-29
EP2158319B1 (en)	2011-12-07
WO2008138131A9 (en)	2009-08-06
NO2016002I2 (no)	2016-02-02
CY2016005I2 (el)	2016-08-31
ATE536413T1 (de)	2011-12-15
US20100297119A1 (en)	2010-11-25
HRP20140416T1 (hr)	2014-06-20
EP2158319A4 (en)	2010-07-21
NL300798I1 (el)	2016-03-16
BR122019000505B1 (pt)	2022-01-18
EP2662448B1 (en)	2016-12-21
ES2380546T3 (es)	2012-05-16
DE202008018131U1 (de)	2011-12-30
EP2662448A1 (en)	2013-11-13
HUE031655T2 (hu)	2017-07-28
NL300798I2 (el)	2016-03-16
PL2662448T3 (pl)	2017-07-31
PL2368999T3 (pl)	2014-08-29

Publication	Publication Date	Title
CY2016005I1 (el)	2016-08-31	Αλκαλικη φωσφαταση στοχευμενη στα οστα, κιτ και μεθοδοι χρησης αυτων
CY2020021I2 (el)	2020-11-25	Αντισωματα και ανοσοσυζευγματα αντι-cd79b και μεθοδοι χρησης
BRPI0814330A2 (pt)	2017-05-23	métodos e kits cirúrgicos
CY2015013I2 (el)	2016-04-13	Αντι-μολυσματικες πυραμιδινες και χρησεις αυτων
BR112012000735A2 (pt)	2016-11-16	"métodos, kits e conjuntos de compostos"
BRPI0819338A2 (pt)	2015-05-19	Preparações, métodos e kits úteis para o tratamento de tosse
BRPI0819980A2 (pt)	2015-06-16	Conjunto e método de sutura
FI20075978A0 (fi)	2007-12-31	Järjestely ja menetelmä
BRPI0809573A8 (pt)	2016-10-11	composição, e, método
DE602009000202D1 (de)	2010-11-04	Positive Resistzusammensetzung und Strukturierungsverfahren
BRPI0716291A2 (pt)	2013-12-24	Método de contracepção e kits farmacêuticos
BRPI0813627A2 (pt)	2014-12-23	Peptídio antimicrobiano, composições e métodos de uso
BRPI0812176A2 (pt)	2014-12-02	Método de cimentar poço
BRPI0814167A2 (pt)	2015-01-20	Composição, e, método
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