[go: up one dir, main page]
More Web Proxy on the site http://driver.im/

CY2009011I2 - Αλατα προσθηκης οξεος παραγωγων υδροπυριδινης - Google Patents

Αλατα προσθηκης οξεος παραγωγων υδροπυριδινης

Info

Publication number
CY2009011I2
CY2009011I2 CY2009011C CY2009011C CY2009011I2 CY 2009011 I2 CY2009011 I2 CY 2009011I2 CY 2009011 C CY2009011 C CY 2009011C CY 2009011 C CY2009011 C CY 2009011C CY 2009011 I2 CY2009011 I2 CY 2009011I2
Authority
CY
Cyprus
Prior art keywords
acid addition
addition salts
hydropyridine derivatives
hydropyridine
derivatives
Prior art date
Application number
CY2009011C
Other languages
English (en)
Other versions
CY2009011I1 (el
Original Assignee
Daiichi Sankyo Company, Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26595526&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CY2009011(I2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Daiichi Sankyo Company, Limited filed Critical Daiichi Sankyo Company, Limited
Publication of CY2009011I1 publication Critical patent/CY2009011I1/el
Publication of CY2009011I2 publication Critical patent/CY2009011I2/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pyridine Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CY2009011C 2000-07-06 2009-08-03 Αλατα προσθηκης οξεος παραγωγων υδροπυριδινης CY2009011I2 (el)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2000205396 2000-07-06
JP2000266780 2000-09-04
PCT/JP2001/005764 WO2002004461A1 (fr) 2000-07-06 2001-07-03 Sels d'addition acides de dérivés hydropyridine

Publications (2)

Publication Number Publication Date
CY2009011I1 CY2009011I1 (el) 2010-07-28
CY2009011I2 true CY2009011I2 (el) 2010-07-28

Family

ID=26595526

Family Applications (3)

Application Number Title Priority Date Filing Date
CY20071100188T CY1107554T1 (el) 2000-07-06 2007-02-12 Αλατα προσθηκης οξεος παραγωγων υδροπυριδινης
CY20081100983T CY1110395T1 (el) 2000-07-06 2008-09-11 Αλατα προσθηκης οξεος παραγωγων υδροπυριδινης
CY2009011C CY2009011I2 (el) 2000-07-06 2009-08-03 Αλατα προσθηκης οξεος παραγωγων υδροπυριδινης

Family Applications Before (2)

Application Number Title Priority Date Filing Date
CY20071100188T CY1107554T1 (el) 2000-07-06 2007-02-12 Αλατα προσθηκης οξεος παραγωγων υδροπυριδινης
CY20081100983T CY1110395T1 (el) 2000-07-06 2008-09-11 Αλατα προσθηκης οξεος παραγωγων υδροπυριδινης

Country Status (24)

Country Link
US (1) US6693115B2 (el)
EP (2) EP1728794B1 (el)
KR (6) KR20120062906A (el)
CN (1) CN1214031C (el)
AT (2) ATE346071T1 (el)
AU (2) AU2001267916B2 (el)
BR (1) BR0112168A (el)
CA (2) CA2703697C (el)
CY (3) CY1107554T1 (el)
CZ (1) CZ302990B6 (el)
DE (2) DE60124712T2 (el)
DK (2) DK1298132T3 (el)
ES (2) ES2308633T3 (el)
HK (2) HK1051362A1 (el)
HU (2) HU230762B1 (el)
IL (2) IL153546A0 (el)
MX (1) MXPA03000031A (el)
NO (1) NO328651B1 (el)
NZ (1) NZ523416A (el)
PL (1) PL208386B1 (el)
PT (2) PT1728794E (el)
RU (1) RU2238275C1 (el)
TW (1) TWI290927B (el)
WO (1) WO2002004461A1 (el)

Families Citing this family (100)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT1350511E (pt) 2000-12-25 2008-10-28 Ube Industries Composições medicinais contendo aspirina
AU2003248077A1 (en) * 2002-07-18 2004-02-09 Sankyo Company, Limited Medicinal composition for treating arteriosclerosis
WO2004098713A2 (en) * 2003-05-05 2004-11-18 Eli Lilly And Company Treating cardiovascular diseases with a compound of formula (i) (cs 747 - prasugrel; rn 150322-43-4)
US20060099261A1 (en) * 2004-11-08 2006-05-11 Biokey, Inc. Methods and formulations for making controlled release oral dosage form
US8586085B2 (en) * 2004-11-08 2013-11-19 Biokey, Inc. Methods and formulations for making pharmaceutical compositions containing bupropion
US20060099262A1 (en) * 2004-11-08 2006-05-11 Biokey, Inc. Methods and formulations for making controlled release oral dosage form
CN1318428C (zh) * 2005-02-23 2007-05-30 天津药物研究院 噻吩并吡啶取代的乙酰肼衍生物
TWI318571B (en) * 2005-06-10 2009-12-21 Lilly Co Eli Formulation of a thienopyridine platelet aggregation inhibitor
EA200800075A1 (ru) * 2005-06-17 2008-04-28 Эли Лилли Энд Компани Схема дозирования для празугреля
EP1940399A2 (en) * 2005-08-19 2008-07-09 Eli Lilly & Company Use of par-i/par- 4 inhibitors for treating or preventing vascular diseases
US8056072B2 (en) 2005-10-31 2011-11-08 Microsoft Corporation Rebootless display driver upgrades
DK2007362T3 (en) 2006-04-04 2018-11-26 Kg Acquisition Llc ORAL DOSAGE FORMS, INCLUDING AN ANTITHROMOBOCYTY AGENT AND AN ACID INHIBITOR
TWI392681B (zh) 2006-04-06 2013-04-11 Daiichi Sankyo Co Ltd 高純度普拉格雷及其酸加成鹽之製法
PL2032521T3 (pl) * 2006-06-27 2010-05-31 Sandoz Ag Nowy sposób wytwarzania soli
WO2008060934A2 (en) * 2006-11-14 2008-05-22 Acusphere, Inc. Formulations of tetrahydropyridine antiplatelet agents for parenteral or oral administration
TWI405591B (zh) * 2006-12-07 2013-08-21 Daiichi Sankyo Co Ltd 固形製劑之製造方法
KR101506043B1 (ko) * 2006-12-07 2015-03-25 다이이찌 산쿄 가부시키가이샤 저치환도 히드록시프로필셀룰로오스를 함유하는 의약 조성물
WO2008072532A1 (ja) * 2006-12-07 2008-06-19 Daiichi Sankyo Company, Limited 貯蔵安定性が改善された医薬組成物
CN101594863B (zh) * 2006-12-07 2011-12-07 第一三共株式会社 具有改进稳定性的涂膜制剂
CN101600430A (zh) * 2006-12-07 2009-12-09 第一三共株式会社 含有甘露糖醇或乳糖的固体药物制剂
CN102424686A (zh) * 2007-03-02 2012-04-25 第一三共株式会社 用于制备高纯度普拉格雷盐酸盐的方法
US8343995B2 (en) 2007-04-27 2013-01-01 Cydex Pharmaceuticals, Inc. Formulations containing clopidogrel and sulfoalkyl ether cyclodextrin and methods of use
CZ302135B6 (cs) * 2007-07-09 2010-11-10 Zentiva, A. S. Zpusob výroby 5-[2-cyklopropyl-1-(2-fluorfenyl)-2-oxoethyl]-4, 5, 6, 7-tetrahydrothieno[3,2-c]pyridin-2-yl acetátu (prasugrelu)
US20100261908A1 (en) * 2007-11-09 2010-10-14 Dr. Reddy's Laboratories Ltd. Processes for the preparation of prasugrel , and its salts and polymorphs
HU230261B1 (hu) * 2007-11-27 2015-11-30 Egis Gyógyszergyár Nyilvánosan Működő Részvénytársaság Eljárás gyógyszeripari intermedierek előállítására
CN101177430A (zh) * 2007-12-11 2008-05-14 鲁南制药集团股份有限公司 氢化吡啶衍生物及其盐的制备方法
WO2009098142A1 (en) * 2008-02-06 2009-08-13 Helm Ag Prasugrel salts with improved properties
WO2009129983A1 (en) * 2008-04-21 2009-10-29 Ratiopharm Gmbh Acid addition salts of prasugrel and pharmaceutical compositions comprising the same
ES2353853T3 (es) * 2008-04-25 2011-03-07 Sandoz Ag SAL HIDROGENOSULFATO DE 2-ACETOXI-5-("ALFA"-CICLOPROPILCARBONIL-2-FLUORBENCIL)-4,5,6,7-TETRAHIDROTIENO[3,2-c]PIRIDINA Y SU PREPARACIÓN.
US20090281136A1 (en) * 2008-05-08 2009-11-12 Sandeep Mhetre Prasugrel pharmaceutical formulations
US9925265B2 (en) 2009-11-11 2018-03-27 Chiesi Farmaceutici S.P.A. Methods of treating or preventing stent thrombosis
US9427448B2 (en) 2009-11-11 2016-08-30 The Medicines Company Methods of treating, reducing the incidence of, and/or preventing ischemic events
US20130303477A1 (en) * 2008-05-13 2013-11-14 The Medicines Company Maintenance of Platelet Inhibition During Antiplatelet Therapy
US8759316B2 (en) * 2008-05-13 2014-06-24 The Medicines Company Maintenance of platelet inhibition during antiplatelet therapy
US20120141468A1 (en) 2008-05-13 2012-06-07 Lisa Ruderman Chen Maintenance of platelet inhibition during antiplatelet therapy
WO2009140092A1 (en) 2008-05-13 2009-11-19 The Medicines Company Maintenance of platelet inhibition during antiplatelet therapy
KR20110045034A (ko) * 2008-08-02 2011-05-03 루난 파마슈티컬 그룹 코퍼레이션 프라수그렐 황산수소염 및 이의 약제학적 조성물 및 용도
EP2398468B1 (en) 2009-02-17 2016-11-30 KRKA, D.D., Novo Mesto Pharmaceutical compositions comprising prasugrel base or its pharmaceutically acceptable acid addition salts and processes for their preparation
US8772488B2 (en) 2009-03-31 2014-07-08 Shanghai Institute Of Pharmaceutical Industry Crystals of prasugrel hydrobromate
EP2990051B1 (en) 2009-04-10 2016-10-26 Tufts Medical Center, Inc. Par-1 activation by metalloproteinase-1 (mmp-1)
KR101912709B1 (ko) 2009-05-13 2018-10-30 사이덱스 파마슈티칼스, 인크. 프라수그렐 및 사이클로덱스트린 유도체를 포함하는 약학 조성물 및 그의 제조 및 사용 방법
WO2011004392A1 (en) * 2009-07-06 2011-01-13 Glenmark Generics Limited Crystalline form of prasugrel hydrobromide, preparation and application thereof
DE102009036646A1 (de) 2009-08-07 2011-02-10 Ratiopharm Gmbh Prasugrel in nicht-kristalliner Form und pharmazeutische Zusammensetzung davon
CN101993447A (zh) 2009-08-26 2011-03-30 浙江华海药业股份有限公司 一种人工合成普拉格雷的方法
WO2011036533A1 (en) * 2009-09-23 2011-03-31 Glenmark Pharmaceuticals Limited Pharmaceutical composition comprising prasugrel and triflusal
US10376532B2 (en) 2009-11-11 2019-08-13 Chiesi Farmaceutici, S.P.A. Methods of treating, reducing the incidence of, and/or preventing ischemic events
CZ2009763A3 (cs) 2009-11-16 2011-05-25 Zentiva, K. S. Zpusob výroby vysoce cistého 5-[2-cyklopropyl-1-(2-fluorfenyl)-2-oxoethyl]-4,5,6,7-tetrahydrothieno[3,2-c]pyridin-2-yl acetátu známého pod nechráneným názvem prasugrel a jeho nových farmaceuticky prijatelných solí.
CZ2009762A3 (cs) 2009-11-16 2011-05-25 Zentiva, K. S. Nové soli 5-[2-cyklopropyl-1-(2-fluorfenyl)-2-oxoethyl]-4,5,6,7-tetrahydrothieno[3,2-c]pyridin-2-yl acetátu známého pod nechráneným názvem prasugrel a zpusob jejich výroby
CZ2009828A3 (cs) 2009-12-09 2011-06-22 Zentiva, K.S. Zpusob prípravy hydrochloridu 5-[2-cyklopropyl-1-(2-fluorfenyl)-2-oxoethyl]-4,5,6,7-tetrahydrothieno[3,2-c]pyridin-2-yl acetátu (prasugrelu hydrochloridu) v polymorfní forme B
HU229035B1 (en) * 2009-12-21 2013-07-29 Egis Gyogyszergyar Nyilvanosan Muekoedoe Reszvenytarsasag Process for producing prasurgel
WO2011092720A2 (en) * 2010-02-01 2011-08-04 Msn Laboratories Limited Pharmaceutical composition of prasugrel and its pharmaceutically acceptable salts
EP2360159A1 (de) * 2010-02-11 2011-08-24 Ratiopharm GmbH Prasugrel in mikronisierter, kristalliner Form und pharmazeutische Zusammensetzung davon
EP2545059A1 (en) 2010-03-09 2013-01-16 Synthon BV A process for making prasugrel
KR101184915B1 (ko) 2010-03-11 2012-09-21 한미사이언스 주식회사 고순도 프라수그렐의 제조방법
WO2011117782A1 (en) 2010-03-23 2011-09-29 Alembic Pharmaceuticals Limited A process for the preparation of prasugrel hcl salt
EP2377520A1 (de) 2010-03-24 2011-10-19 Ratiopharm GmbH Pharmazeutische Zusammensetzung des Prasugrels
CN102212068A (zh) * 2010-04-06 2011-10-12 刘桂坤 噻吩衍生物及其制备方法和在药物上的应用
CN102212071B (zh) * 2010-04-08 2014-03-26 上海医药工业研究院 普拉格雷盐酸盐乙酸溶剂合物及其结晶和制备方法
WO2011127300A1 (en) 2010-04-08 2011-10-13 Teva Pharmaceutical Industries Ltd. Crystalline forms of prasugrel salts
EP2560644B1 (en) 2010-04-19 2016-06-29 Cadila Healthcare Limited A pharmaceutical composition comprising antiplatelet agents and an erythropoiesis stimulating agent
WO2012001486A1 (en) * 2010-06-28 2012-01-05 Mayuka Labs Pvt. Ltd. An improved process for the preparation of prasugrel hydrochloride and its intermediates
TR201007926A1 (tr) 2010-07-19 2012-02-21 Sanovel İlaç San.Ve Ti̇c.A.Ş. Prasugrel tablet formülasyonları.
EP2409685A3 (en) 2010-07-19 2012-02-01 Sanovel Ilac Sanayi ve Ticaret A.S. Orally-disintegrating formulations of prasugrel
TR201006802A1 (tr) * 2010-08-17 2012-03-21 Sanovel İlaç San. Ve Ti̇c. A.Ş. Prasugrelin oral yolla dağılan formülasyonları.
TR201005900A1 (tr) 2010-07-19 2012-02-21 Sanovel İlaç San. Ve Ti̇c. A.Ş. Geliştirilmiş stabiliteye sahip prasugrel granülleri.
WO2012023145A2 (en) * 2010-08-18 2012-02-23 Hetero Research Foundation Prasugrel hydrochloride crystalline particles
HUP1000565A2 (en) 2010-10-22 2012-05-02 Egis Gyogyszergyar Nyrt Process for the preparation of pharmaceutically active compound and intermediers
CN101985450B (zh) * 2010-11-02 2012-07-11 北京赛科药业有限责任公司 普拉格雷盐及其制备方法
CN102532157A (zh) * 2010-12-16 2012-07-04 瑞阳制药有限公司 普拉格雷的可药用酸加成盐化合物及其制备方法
CZ305314B6 (cs) * 2010-12-30 2015-07-29 Zentiva, K.S. Nový hydrobromid formy C 5-[2-cyklopropyl-1-(2-fluorofenyl)-2-oxoethyl]-4,5,6,7-tetrahydrothieno[3,2-c]pyridin-2-yl acetátu známého pod nechráněným názvem prasugrel a způsob jeho výroby
CN102199163A (zh) * 2011-04-01 2011-09-28 中国药科大学 2-羟基四氢噻吩并吡啶衍生物及其制备方法与在制药中的用途
CN102746318A (zh) * 2011-04-20 2012-10-24 上海信谊药厂有限公司 用于制备普拉格雷盐酸盐的方法
US9788539B2 (en) 2011-05-17 2017-10-17 Velico Medical, Inc. Platelet protection solution having beta-galactosidase and sialidase inhibitors
US9609861B2 (en) 2011-05-17 2017-04-04 Velico Medical Inc. Platelet additive solution having a β-galactosidase inhibitor
EP2709446A2 (en) 2011-05-17 2014-03-26 Velico Medical, Inc. Platelet storage using a sialidase inhibitor
CN102838618A (zh) * 2011-06-22 2012-12-26 广东东阳光药业有限公司 一种制备普拉格雷的方法及普拉格雷盐酸盐新晶型
ES2557199T3 (es) 2011-07-28 2016-01-22 Laboratorios Lesvi, S.L. Procedimiento para la preparación de prasugrel
CN103102355A (zh) * 2011-11-09 2013-05-15 丁克 具有旋光性的四氢噻吩并吡啶化合物
CZ2011872A3 (cs) 2011-12-22 2013-07-03 Zentiva, K.S. Farmaceutická formulace prasugrelu hydrobromidu
US8603537B2 (en) 2012-04-02 2013-12-10 Egis Pharmaceuticals Plc Prasugrel containing quickly released stable oral pharmaceutical compositions
WO2014060560A1 (en) 2012-10-19 2014-04-24 Sanovel Ilac Sanayi Ve Ticaret A.S. Solid oral formulations of prasugrel
EP2722037A1 (en) 2012-10-19 2014-04-23 Sanovel Ilac Sanayi ve Ticaret A.S. Prasugrel formulations
PL402028A1 (pl) 2012-12-12 2014-06-23 Instytut Farmaceutyczny Sposób wytwarzania postaci polimorficznej B chlorowodorku prasugrelu o czystości farmaceutycznej
HU230649B1 (hu) 2013-01-24 2017-05-29 Egis Gyógyszergyár Nyilvánosan Működő Részvénytársaság Javított eljárás prasugrel gyógyszeripari hatóanyag és az 1-ciklopropil-2-(2-fluorofenil)-etanon intermedier előállítására
WO2014120886A1 (en) 2013-01-30 2014-08-07 Velico Medical, Inc. Platelet additive solution having a self-assembling hydrogel-forming peptide
KR102235732B1 (ko) 2013-12-26 2021-04-02 에스케이플래닛 주식회사 쿠폰 관리 시스템 및 방법, 그리고 이를 위한 장치 및 컴퓨터 프로그램이 기록된 기록매체
DE102014108210A1 (de) 2014-06-11 2015-12-17 Dietrich Gulba Rodentizid
EP2979693A1 (en) 2014-08-01 2016-02-03 Zaklady Farmaceutyczne Polpharma SA Pharmaceutical composition comprising prasugrel or pharmaceutically acceptable salt thereof and process for its preparation
CN104479502A (zh) * 2014-12-31 2015-04-01 江阴市天邦涂料股份有限公司 一种水性防腐涂料
WO2016122421A1 (en) 2015-01-29 2016-08-04 Pharmactive Ilaç Sanayi Ve Ticaret A.Ş. Stable pharmaceutical compositions containing prasugrel base
EP3106151A1 (en) 2015-06-19 2016-12-21 Sanovel Ilac Sanayi ve Ticaret A.S. Pharmaceutical compositions of prasugrel hydrobromide
EP3156049A1 (en) 2015-10-15 2017-04-19 Alembic Pharmaceuticals Limited Pharmaceutical composition of prasugrel
EP3158993A1 (en) 2015-10-22 2017-04-26 Zaklady Farmaceutyczne Polpharma SA Process for preparing a tablet comprising prasugrel or pharmaceutically acceptable salt thereof
HU231079B1 (hu) 2016-06-23 2020-06-29 Richter Gedeon Nyrt. Eljárás nagytisztaságú Prasugrel előállítására bromopentil szennyezés eltávolításával
EP3528790A1 (en) 2016-10-21 2019-08-28 Laboratorios Lesvi S.L. Pharmaceutical formulations of prasugrel and processes for the preparation thereof
CN106632391A (zh) * 2016-12-23 2017-05-10 山东鲁抗医药股份有限公司 一种盐酸普拉格雷化合物及其制备方法和含有盐酸普拉格雷的药物组合物
CA3060345A1 (en) 2017-06-23 2018-12-27 Chiesi Farmaceutici S.P.A. Method of preventing of systemic-to-pulmonary-artery shunt thrombosis
KR102063862B1 (ko) 2018-08-09 2020-01-08 한국기술교육대학교 산학협력단 Qr코드 기반의 공유시점관리 시스템
KR102491932B1 (ko) 2020-11-18 2023-01-27 현대엠시스템즈 주식회사 통신 방식 가변형 원격 모니터링 제어 시스템 및 방법
KR102485021B1 (ko) 2020-11-18 2023-01-05 효성중공업 주식회사 델타구조 반도체변압기 기반 에너지 저장장치의 SoC 균등제어 장치 및 방법

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4141894A (en) * 1976-11-02 1979-02-27 Eli Lilly And Company Trans-5a-aryl-decahydrobenzazepines
FR2576901B1 (fr) 1985-01-31 1987-03-20 Sanofi Sa Nouveaux derives de l'acide a-(oxo-2 hexahydro-2,4,5,6,7,7a thieno (3,2-c) pyridyl-5) phenyl acetique, leur procede de preparation et leur application therapeutique
JP2506376B2 (ja) * 1987-07-16 1996-06-12 三菱化学株式会社 ２−（４−メチルアミノブトキシ）ジフェニルメタン・塩酸塩の製造方法
FI101150B (fi) * 1991-09-09 1998-04-30 Sankyo Co Menetelmä lääkeaineina käyttökelpoisten tetrahydrotienopyridiinin johd annaisten valmistamiseksi
US5342851A (en) * 1992-10-07 1994-08-30 Mcneil-Ppc, Inc. Substituted thiazole derivatives useful as platelet aggregation inhibitors
JPH07188168A (ja) * 1993-12-28 1995-07-25 Fujisawa Pharmaceut Co Ltd ジヒドロピリジン化合物およびその製造方法
PT1350511E (pt) * 2000-12-25 2008-10-28 Ube Industries Composições medicinais contendo aspirina
CZ2009762A3 (cs) 2009-11-16 2011-05-25 Zentiva, K. S. Nové soli 5-[2-cyklopropyl-1-(2-fluorfenyl)-2-oxoethyl]-4,5,6,7-tetrahydrothieno[3,2-c]pyridin-2-yl acetátu známého pod nechráneným názvem prasugrel a zpusob jejich výroby
CZ305314B6 (cs) 2010-12-30 2015-07-29 Zentiva, K.S. Nový hydrobromid formy C 5-[2-cyklopropyl-1-(2-fluorofenyl)-2-oxoethyl]-4,5,6,7-tetrahydrothieno[3,2-c]pyridin-2-yl acetátu známého pod nechráněným názvem prasugrel a způsob jeho výroby

Also Published As

Publication number Publication date
EP1728794A1 (en) 2006-12-06
PL208386B1 (pl) 2011-04-29
KR20120062906A (ko) 2012-06-14
DE60124712D1 (de) 2007-01-04
PT1728794E (pt) 2008-07-15
IL153546A (en) 2007-03-08
CA2703697A1 (en) 2002-01-17
IL153546A0 (en) 2003-07-06
CZ302990B6 (cs) 2012-02-08
HUP0301645A2 (hu) 2003-09-29
ATE346071T1 (de) 2006-12-15
BR0112168A (pt) 2003-09-02
WO2002004461A1 (fr) 2002-01-17
ES2308633T3 (es) 2008-12-01
EP1728794B1 (en) 2008-06-18
ES2276801T3 (es) 2007-07-01
CY1107554T1 (el) 2010-07-28
CN1214031C (zh) 2005-08-10
KR20080021152A (ko) 2008-03-06
HK1096684A1 (en) 2007-07-20
DK1728794T3 (da) 2008-09-22
CY1110395T1 (el) 2015-04-29
KR20100105763A (ko) 2010-09-29
CY2009011I1 (el) 2010-07-28
KR20130118395A (ko) 2013-10-29
NO328651B1 (no) 2010-04-19
NO20030022L (no) 2003-03-05
AU2001267916B2 (en) 2004-09-09
HU230762B1 (hu) 2018-03-28
AU6791601A (en) 2002-01-21
PT1298132E (pt) 2007-01-31
ATE398624T1 (de) 2008-07-15
DE60134508D1 (de) 2008-07-31
NZ523416A (en) 2004-10-29
KR20090033917A (ko) 2009-04-06
EP1298132A4 (en) 2004-03-10
US6693115B2 (en) 2004-02-17
CA2415558A1 (en) 2002-01-17
NO20030022D0 (no) 2003-01-03
RU2238275C1 (ru) 2004-10-20
EP1298132B1 (en) 2006-11-22
CA2415558C (en) 2010-09-14
EP1298132A1 (en) 2003-04-02
CN1452624A (zh) 2003-10-29
DK1298132T3 (da) 2007-03-12
TWI290927B (en) 2007-12-11
CZ200318A3 (cs) 2003-05-14
PL359393A1 (en) 2004-08-23
HK1051362A1 (en) 2003-08-01
MXPA03000031A (es) 2003-10-15
DE60124712T2 (de) 2007-09-13
US20030134872A1 (en) 2003-07-17
HU227746B1 (en) 2012-02-28
HUP1100350A2 (en) 2003-09-29
CA2703697C (en) 2012-09-04
KR20030014294A (ko) 2003-02-15
HUP0301645A3 (en) 2006-05-29

Similar Documents

Publication Publication Date Title
CY2009011I2 (el) Αλατα προσθηκης οξεος παραγωγων υδροπυριδινης
AU2001267916A1 (en) Hydropyridine derivative acid addition salts
IS8231A (is) Lyfjafræðilega gagnleg sölt karboxýlsýruafleiða
ITMI20000092A0 (it) Sali di agenti antimicrobici
NO20031784D0 (no) Heteroarylalkylpiperazinderivater som fettsyre- oksydasjonsinhibitorer
AR028596A1 (es) Nuevos derivados de fenilglicina
DE50212761D1 (de) Neuartige aminodicarbonsäurederivate
ATE304997T1 (de) Derivate von beta-aminosäurenitrilen
ATE267592T1 (de) Klare wässrige anästhesierende zusammensetzung
EE200400023A (et) Uued sulfoonhappe derivaadid
IS8232A (is) Lyfjafræðilega gagnleg sölt karboxýlsýruafleiða
FI19991703A (fi) Menetelmä ammoniakkipitoisen vesiliuoksen haihduttamiseksi
PT1432685E (pt) Hidratos cristalinos de derivados de anilida do acido nicotinico e de benzoilanilida
DK1328499T3 (da) Fremgangsmåde til fremstilling af carboxylsyresalte
DE60043730D1 (de) Arylsulfonamid-substituierte hydroxamsäure-derivate
DK1254118T3 (da) Substituerede 1,2,3,4-tetrahudroquinolin-2-carboxylsyrederivater
NO20025542L (no) Kinolonkarboksylsyrederivater
PT1322592E (pt) Derivados substituidos de 1-aminobutan-3-ol
DE60132511D1 (de) E-isomeren von fullerenderivate
HK1073102A1 (en) Sulphonic acid salts of mandelic acid derivatives
ATE428691T1 (de) 3-phenyl-2-arylalkylthiopropionsäure-derivate als selektive agonisten von ppar-alpha
EE200100381A (et) Morfolinobensamiidi uued soolad
NO20030375D0 (no) N-substituerte 1-amino-1,1-dialkylkarboksylsyrederivater
DK1497290T3 (da) Fremgangsmåde til fremstilling af syresalte af gemifloxacin
NO20015042D0 (no) Fremgangsmåter for fremstilling av optisk aktive aminosyrederivater