CY1116189T1 - Σταθερη υγρη φαρμακευτικη συνθεση με βαση την τραζοδονη - Google Patents
Σταθερη υγρη φαρμακευτικη συνθεση με βαση την τραζοδονηInfo
- Publication number
- CY1116189T1 CY1116189T1 CY20151100342T CY151100342T CY1116189T1 CY 1116189 T1 CY1116189 T1 CY 1116189T1 CY 20151100342 T CY20151100342 T CY 20151100342T CY 151100342 T CY151100342 T CY 151100342T CY 1116189 T1 CY1116189 T1 CY 1116189T1
- Authority
- CY
- Cyprus
- Prior art keywords
- pharmaceutical composition
- stable liquid
- liquid pharmaceutical
- treasury
- based stable
- Prior art date
Links
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 3
- 239000007788 liquid Substances 0.000 title abstract 2
- 239000002253 acid Substances 0.000 abstract 1
- 239000007864 aqueous solution Substances 0.000 abstract 1
- 150000002334 glycols Chemical class 0.000 abstract 1
- 229920000151 polyglycol Polymers 0.000 abstract 1
- 239000010695 polyglycol Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
- PHLBKPHSAVXXEF-UHFFFAOYSA-N trazodone Chemical compound ClC1=CC=CC(N2CCN(CCCN3C(N4C=CC=CC4=N3)=O)CC2)=C1 PHLBKPHSAVXXEF-UHFFFAOYSA-N 0.000 abstract 1
- 229960003991 trazodone Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Dermatology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Physiology (AREA)
- Nutrition Science (AREA)
- Neurology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Abstract
Μια σταθερή υγρή φαρμακευτική σύνθεση που περιλαμβάνει ένα υδατικό διάλυμα ενός φαρμακευτικά αποδεκτού άλατος προσθήκης οξέος της τραζοδόνης, που χαρακτηρίζεται από το ότι η αναφερθείσα φαρμακευτική σύνθεση έχει τιμή pΗ μεταξύ 5.0 και 6.0, και περιλαμβάνει τουλάχιστον δύο συνδιαλύτες που επιλέγονται από την ομάδα που περιλαμβάνει τις γλυκόλες και τις πολυγλυκόλες.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT001573A ITMI20071573A1 (it) | 2007-07-31 | 2007-07-31 | Composizione farmaceutica liquida stabile a base di trazodone |
EP12170235.1A EP2494955B1 (en) | 2007-07-31 | 2008-07-22 | Stable liquid pharmaceutical composition based on trazodone |
Publications (1)
Publication Number | Publication Date |
---|---|
CY1116189T1 true CY1116189T1 (el) | 2017-02-08 |
Family
ID=38858941
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CY20151100342T CY1116189T1 (el) | 2007-07-31 | 2015-04-09 | Σταθερη υγρη φαρμακευτικη συνθεση με βαση την τραζοδονη |
Country Status (25)
Country | Link |
---|---|
US (1) | US10292931B2 (el) |
EP (2) | EP2182920B1 (el) |
JP (1) | JP5426548B2 (el) |
KR (1) | KR101493370B1 (el) |
CN (1) | CN101784257B (el) |
AR (1) | AR068327A1 (el) |
AU (1) | AU2008281858B2 (el) |
BR (1) | BRPI0814658A2 (el) |
CA (1) | CA2692975C (el) |
CY (1) | CY1116189T1 (el) |
DK (2) | DK2494955T3 (el) |
EA (1) | EA016822B1 (el) |
ES (2) | ES2531241T3 (el) |
GE (1) | GEP20125525B (el) |
HK (2) | HK1138207A1 (el) |
HR (1) | HRP20150349T1 (el) |
IL (1) | IL203167A (el) |
IT (1) | ITMI20071573A1 (el) |
MX (1) | MX2010001092A (el) |
PL (2) | PL2182920T3 (el) |
PT (2) | PT2182920E (el) |
SG (1) | SG183659A1 (el) |
SI (2) | SI2494955T1 (el) |
UA (1) | UA102376C2 (el) |
WO (1) | WO2009016069A2 (el) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ITMI20071603A1 (it) | 2007-08-03 | 2009-02-04 | Acraf | Trazodone e trazodone cloridrato in forma purificata |
WO2012072665A1 (en) | 2010-11-30 | 2012-06-07 | Pharmaneuroboost N.V. | Compositions comprising pipamperone and serotonin antagonist reuptake inhibitors |
RU2706700C1 (ru) * | 2019-09-24 | 2019-11-20 | Общество с ограниченной ответственностью "Научно-производственная компания "СКиФФ" | Фармацевтическая композиция для коррекции поведения кошек и собак в стрессовых ситуациях |
US20220331312A1 (en) * | 2019-09-26 | 2022-10-20 | Angelini S.P.A. | Pediatric trazodone compositions and method of treatment thereof |
CN111568861A (zh) * | 2020-05-25 | 2020-08-25 | 河北科星药业有限公司 | 畜禽用盐酸溴己新口服液及其制备方法和应用 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4154832A (en) * | 1974-08-26 | 1979-05-15 | Bruno Silvestrini | Novel treatment for acute organic cerebral syndromes (strokes) |
IT1233412B (it) * | 1987-12-02 | 1992-03-30 | Acraf | Uso del trazodone |
EP1113785B1 (en) * | 1998-07-24 | 2005-04-13 | Seo Hong Yoo | Clear aqueous solutions of bile acids |
AU2003903597A0 (en) * | 2003-07-11 | 2003-07-24 | Jakov Vaisman | Treatment of premature ejaculation |
ITMI20071603A1 (it) | 2007-08-03 | 2009-02-04 | Acraf | Trazodone e trazodone cloridrato in forma purificata |
-
2007
- 2007-07-31 IT IT001573A patent/ITMI20071573A1/it unknown
-
2008
- 2008-07-22 EA EA201070194A patent/EA016822B1/ru not_active IP Right Cessation
- 2008-07-22 US US12/667,694 patent/US10292931B2/en active Active
- 2008-07-22 PT PT87752788T patent/PT2182920E/pt unknown
- 2008-07-22 CA CA2692975A patent/CA2692975C/en active Active
- 2008-07-22 JP JP2010518618A patent/JP5426548B2/ja active Active
- 2008-07-22 PL PL08775278T patent/PL2182920T3/pl unknown
- 2008-07-22 PL PL12170235T patent/PL2494955T3/pl unknown
- 2008-07-22 BR BRPI0814658-6A2A patent/BRPI0814658A2/pt not_active Application Discontinuation
- 2008-07-22 DK DK12170235T patent/DK2494955T3/en active
- 2008-07-22 SG SG2012055679A patent/SG183659A1/en unknown
- 2008-07-22 EP EP08775278A patent/EP2182920B1/en active Active
- 2008-07-22 PT PT12170235T patent/PT2494955E/pt unknown
- 2008-07-22 EP EP12170235.1A patent/EP2494955B1/en active Active
- 2008-07-22 DK DK08775278.8T patent/DK2182920T3/da active
- 2008-07-22 UA UAA201000864A patent/UA102376C2/ru unknown
- 2008-07-22 GE GEAP200811704A patent/GEP20125525B/en unknown
- 2008-07-22 SI SI200831393T patent/SI2494955T1/sl unknown
- 2008-07-22 AU AU2008281858A patent/AU2008281858B2/en active Active
- 2008-07-22 ES ES12170235T patent/ES2531241T3/es active Active
- 2008-07-22 MX MX2010001092A patent/MX2010001092A/es active IP Right Grant
- 2008-07-22 ES ES08775278T patent/ES2399569T3/es active Active
- 2008-07-22 WO PCT/EP2008/059605 patent/WO2009016069A2/en active Application Filing
- 2008-07-22 CN CN2008801012992A patent/CN101784257B/zh active Active
- 2008-07-22 KR KR1020107002151A patent/KR101493370B1/ko active IP Right Grant
- 2008-07-22 SI SI200830897T patent/SI2182920T1/sl unknown
- 2008-07-30 AR ARP080103285A patent/AR068327A1/es not_active Application Discontinuation
-
2010
- 2010-01-06 IL IL203167A patent/IL203167A/en active IP Right Grant
- 2010-05-19 HK HK10104941.0A patent/HK1138207A1/xx unknown
- 2010-05-19 HK HK13102337.3A patent/HK1176280A1/xx unknown
-
2015
- 2015-03-27 HR HRP20150349TT patent/HRP20150349T1/hr unknown
- 2015-04-09 CY CY20151100342T patent/CY1116189T1/el unknown
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