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CY1116189T1 - Σταθερη υγρη φαρμακευτικη συνθεση με βαση την τραζοδονη - Google Patents

Σταθερη υγρη φαρμακευτικη συνθεση με βαση την τραζοδονη

Info

Publication number
CY1116189T1
CY1116189T1 CY20151100342T CY151100342T CY1116189T1 CY 1116189 T1 CY1116189 T1 CY 1116189T1 CY 20151100342 T CY20151100342 T CY 20151100342T CY 151100342 T CY151100342 T CY 151100342T CY 1116189 T1 CY1116189 T1 CY 1116189T1
Authority
CY
Cyprus
Prior art keywords
pharmaceutical composition
stable liquid
liquid pharmaceutical
treasury
based stable
Prior art date
Application number
CY20151100342T
Other languages
English (en)
Inventor
Marcello Marchetti
Original Assignee
Aziende Chimiche Riunite Angelini Francesco A.C.R.A.F. S.P.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aziende Chimiche Riunite Angelini Francesco A.C.R.A.F. S.P.A. filed Critical Aziende Chimiche Riunite Angelini Francesco A.C.R.A.F. S.P.A.
Publication of CY1116189T1 publication Critical patent/CY1116189T1/el

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0087Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Neurology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

Μια σταθερή υγρή φαρμακευτική σύνθεση που περιλαμβάνει ένα υδατικό διάλυμα ενός φαρμακευτικά αποδεκτού άλατος προσθήκης οξέος της τραζοδόνης, που χαρακτηρίζεται από το ότι η αναφερθείσα φαρμακευτική σύνθεση έχει τιμή pΗ μεταξύ 5.0 και 6.0, και περιλαμβάνει τουλάχιστον δύο συνδιαλύτες που επιλέγονται από την ομάδα που περιλαμβάνει τις γλυκόλες και τις πολυγλυκόλες.
CY20151100342T 2007-07-31 2015-04-09 Σταθερη υγρη φαρμακευτικη συνθεση με βαση την τραζοδονη CY1116189T1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT001573A ITMI20071573A1 (it) 2007-07-31 2007-07-31 Composizione farmaceutica liquida stabile a base di trazodone
EP12170235.1A EP2494955B1 (en) 2007-07-31 2008-07-22 Stable liquid pharmaceutical composition based on trazodone

Publications (1)

Publication Number Publication Date
CY1116189T1 true CY1116189T1 (el) 2017-02-08

Family

ID=38858941

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20151100342T CY1116189T1 (el) 2007-07-31 2015-04-09 Σταθερη υγρη φαρμακευτικη συνθεση με βαση την τραζοδονη

Country Status (25)

Country Link
US (1) US10292931B2 (el)
EP (2) EP2182920B1 (el)
JP (1) JP5426548B2 (el)
KR (1) KR101493370B1 (el)
CN (1) CN101784257B (el)
AR (1) AR068327A1 (el)
AU (1) AU2008281858B2 (el)
BR (1) BRPI0814658A2 (el)
CA (1) CA2692975C (el)
CY (1) CY1116189T1 (el)
DK (2) DK2494955T3 (el)
EA (1) EA016822B1 (el)
ES (2) ES2531241T3 (el)
GE (1) GEP20125525B (el)
HK (2) HK1138207A1 (el)
HR (1) HRP20150349T1 (el)
IL (1) IL203167A (el)
IT (1) ITMI20071573A1 (el)
MX (1) MX2010001092A (el)
PL (2) PL2182920T3 (el)
PT (2) PT2182920E (el)
SG (1) SG183659A1 (el)
SI (2) SI2494955T1 (el)
UA (1) UA102376C2 (el)
WO (1) WO2009016069A2 (el)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ITMI20071603A1 (it) 2007-08-03 2009-02-04 Acraf Trazodone e trazodone cloridrato in forma purificata
WO2012072665A1 (en) 2010-11-30 2012-06-07 Pharmaneuroboost N.V. Compositions comprising pipamperone and serotonin antagonist reuptake inhibitors
RU2706700C1 (ru) * 2019-09-24 2019-11-20 Общество с ограниченной ответственностью "Научно-производственная компания "СКиФФ" Фармацевтическая композиция для коррекции поведения кошек и собак в стрессовых ситуациях
US20220331312A1 (en) * 2019-09-26 2022-10-20 Angelini S.P.A. Pediatric trazodone compositions and method of treatment thereof
CN111568861A (zh) * 2020-05-25 2020-08-25 河北科星药业有限公司 畜禽用盐酸溴己新口服液及其制备方法和应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4154832A (en) * 1974-08-26 1979-05-15 Bruno Silvestrini Novel treatment for acute organic cerebral syndromes (strokes)
IT1233412B (it) * 1987-12-02 1992-03-30 Acraf Uso del trazodone
EP1113785B1 (en) * 1998-07-24 2005-04-13 Seo Hong Yoo Clear aqueous solutions of bile acids
AU2003903597A0 (en) * 2003-07-11 2003-07-24 Jakov Vaisman Treatment of premature ejaculation
ITMI20071603A1 (it) 2007-08-03 2009-02-04 Acraf Trazodone e trazodone cloridrato in forma purificata

Also Published As

Publication number Publication date
MX2010001092A (es) 2010-03-01
CA2692975C (en) 2016-01-12
EP2494955B1 (en) 2015-01-21
US20100256159A1 (en) 2010-10-07
SI2182920T1 (sl) 2013-04-30
IL203167A (en) 2017-08-31
WO2009016069A3 (en) 2009-03-19
PT2182920E (pt) 2013-03-07
JP2010534703A (ja) 2010-11-11
UA102376C2 (ru) 2013-07-10
AU2008281858A1 (en) 2009-02-05
HK1138207A1 (en) 2010-08-20
BRPI0814658A2 (pt) 2015-02-18
EA201070194A1 (ru) 2010-06-30
HRP20150349T1 (hr) 2015-05-22
KR20100038112A (ko) 2010-04-12
WO2009016069A2 (en) 2009-02-05
EP2182920A2 (en) 2010-05-12
ES2399569T3 (es) 2013-04-02
AU2008281858B2 (en) 2014-02-27
DK2182920T3 (da) 2013-03-04
PT2494955E (pt) 2015-03-04
JP5426548B2 (ja) 2014-02-26
CN101784257A (zh) 2010-07-21
ES2531241T3 (es) 2015-03-12
US10292931B2 (en) 2019-05-21
EP2182920B1 (en) 2012-12-26
CN101784257B (zh) 2012-11-28
EP2494955A2 (en) 2012-09-05
ITMI20071573A1 (it) 2009-02-01
PL2182920T3 (pl) 2013-05-31
CA2692975A1 (en) 2009-02-05
WO2009016069A4 (en) 2009-05-14
EP2494955A3 (en) 2012-10-03
DK2494955T3 (en) 2015-04-13
SG183659A1 (en) 2012-09-27
PL2494955T3 (pl) 2015-06-30
HK1176280A1 (en) 2013-07-26
KR101493370B1 (ko) 2015-02-13
SI2494955T1 (sl) 2015-04-30
GEP20125525B (en) 2012-05-25
EA016822B1 (ru) 2012-07-30
AR068327A1 (es) 2009-11-11

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