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CY1112874T1 - Φαρμακευτικες μορφες με βελτιωμενες φαρμακοκινητικες ιδιοτητες - Google Patents

Φαρμακευτικες μορφες με βελτιωμενες φαρμακοκινητικες ιδιοτητες

Info

Publication number
CY1112874T1
CY1112874T1 CY20121100558T CY121100558T CY1112874T1 CY 1112874 T1 CY1112874 T1 CY 1112874T1 CY 20121100558 T CY20121100558 T CY 20121100558T CY 121100558 T CY121100558 T CY 121100558T CY 1112874 T1 CY1112874 T1 CY 1112874T1
Authority
CY
Cyprus
Prior art keywords
pharmacokinetic properties
pharmaceutical forms
improved pharmacokinetic
vardenafil
plateau
Prior art date
Application number
CY20121100558T
Other languages
English (en)
Inventor
Peter Serno
Roland Heinig
Kerstin Pauli
Yutaka Hayauchi
Original Assignee
Bayer Pharma Aktiengesellschaft
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=36264023&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CY1112874(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Bayer Pharma Aktiengesellschaft filed Critical Bayer Pharma Aktiengesellschaft
Publication of CY1112874T1 publication Critical patent/CY1112874T1/el

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/53—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with three nitrogens as the only ring hetero atoms, e.g. chlorazanil, melamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Zoology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Reproductive Health (AREA)
  • Endocrinology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

Η παρούσα αίτηση αφορά νέες φαρμακευτικές χημικές συνθέσεις βαρντεναφίλης, οι οποίες διαλύονται ταχέως στο στόμα και οδηγούν σε μια αύξηση στη βιοδιαθεσιμότητα και σε μια καμπύλη συγκέντρωσης πλάσματος που μοιάζει με υψίπεδο, καθώς και μέθοδο για την παρασκευή τους.
CY20121100558T 2005-03-01 2012-06-20 Φαρμακευτικες μορφες με βελτιωμενες φαρμακοκινητικες ιδιοτητες CY1112874T1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102005009240A DE102005009240A1 (de) 2005-03-01 2005-03-01 Arzneiformen mit verbesserten pharmakokinetischen Eigenschaften
EP06706994A EP1858490B1 (de) 2005-03-01 2006-02-16 Arzneiformen mit verbesserten pharmakokinetischen eigenschaften

Publications (1)

Publication Number Publication Date
CY1112874T1 true CY1112874T1 (el) 2016-04-13

Family

ID=36264023

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20121100558T CY1112874T1 (el) 2005-03-01 2012-06-20 Φαρμακευτικες μορφες με βελτιωμενες φαρμακοκινητικες ιδιοτητες

Country Status (39)

Country Link
US (2) US8613950B2 (el)
EP (2) EP1858490B1 (el)
JP (1) JP5122984B2 (el)
KR (1) KR101360526B1 (el)
CN (2) CN101141950B (el)
AR (2) AR053552A1 (el)
AT (1) ATE552828T1 (el)
AU (1) AU2006220100B2 (el)
BR (1) BRPI0609375A2 (el)
CA (1) CA2599617C (el)
CR (2) CR9339A (el)
CY (1) CY1112874T1 (el)
DE (1) DE102005009240A1 (el)
DK (1) DK1858490T3 (el)
DO (1) DOP2006000049A (el)
ES (1) ES2384109T3 (el)
GT (1) GT200600097A (el)
HK (1) HK1118457A1 (el)
HN (1) HN2006009000A (el)
HR (1) HRP20120545T1 (el)
IL (2) IL185552A (el)
MA (1) MA29376B1 (el)
MX (1) MX2007010527A (el)
MY (2) MY177386A (el)
NO (2) NO332368B1 (el)
NZ (1) NZ561004A (el)
PE (2) PE20100740A1 (el)
PL (1) PL1858490T3 (el)
PT (1) PT1858490E (el)
RS (1) RS52374B (el)
RU (2) RU2423970C2 (el)
SG (1) SG160330A1 (el)
SI (1) SI1858490T1 (el)
TN (1) TNSN07336A1 (el)
TW (1) TWI387465B (el)
UA (1) UA93200C2 (el)
UY (1) UY29395A1 (el)
WO (1) WO2006092207A1 (el)
ZA (1) ZA200707320B (el)

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DE102005009241A1 (de) * 2005-03-01 2006-09-07 Bayer Healthcare Ag Arzneiformen mit kontrollierter Bioverfügbarkeit
FR2906140B1 (fr) * 2006-09-22 2008-12-05 Philippe Perovitch Forme galenique pour l'administration par voie trans-muqueuse de principes actifs
DE102007027067A1 (de) * 2007-06-12 2008-12-18 Ratiopharm Gmbh Verfahren zur Herstellung eines Arzneimittels enthaltend Vardenafil Hydrochlorid Trihydrat
DE102009020888A1 (de) * 2009-05-12 2010-11-18 Ratiopharm Gmbh Schmelztablette, enthaltend ein Vardenafil-Salz
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CN108272765B (zh) * 2018-04-26 2021-02-02 江西杏林白马药业股份有限公司 含盐酸伐地那非的药物组合物、口崩片及其制备、应用
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CN110840851A (zh) * 2019-08-16 2020-02-28 天津仁卫生物医药科技有限公司 一种盐酸伐地那非口腔崩解片及其制备方法
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JP2023513045A (ja) 2020-01-31 2023-03-30 ナノコピーア リミテッド ライアビリティ カンパニー 非晶質ニロチニブ微粒子及びその使用
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