CY1112116T1 - Μεθοδος θεραπειας ασθενων με ηπατιτιδα c - Google Patents
Μεθοδος θεραπειας ασθενων με ηπατιτιδα cInfo
- Publication number
- CY1112116T1 CY1112116T1 CY20111101045T CY111101045T CY1112116T1 CY 1112116 T1 CY1112116 T1 CY 1112116T1 CY 20111101045 T CY20111101045 T CY 20111101045T CY 111101045 T CY111101045 T CY 111101045T CY 1112116 T1 CY1112116 T1 CY 1112116T1
- Authority
- CY
- Cyprus
- Prior art keywords
- patients
- treatment
- relapsed
- hepatitis
- infection
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/4965—Non-condensed pyrazines
- A61K31/497—Non-condensed pyrazines containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/21—Interferons [IFN]
- A61K38/212—IFN-alpha
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/576—Immunoassay; Biospecific binding assay; Materials therefor for hepatitis
- G01N33/5767—Immunoassay; Biospecific binding assay; Materials therefor for hepatitis non-A, non-B hepatitis
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Communicable Diseases (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Virology (AREA)
- Hematology (AREA)
- Biotechnology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Organic Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Gastroenterology & Hepatology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Pathology (AREA)
- Cell Biology (AREA)
- Zoology (AREA)
- Food Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Steroid Compounds (AREA)
Abstract
Η εφαρμογή αυτή αποκαλύπτει νέα μέθοδο αναγνώρισης ασθενών μεταξύ πρωτοθεραπευόμενων ασθενών που πάσχουν από μόλυνση HCV οι οποίοι είναι επιδεκτικοί σε θεραπευτική αγωγή με αναστολέα πρωτεάσης. Η αίτηση επίσης αποκαλύπτει μέθοδο θεραπευτικής αγωγής πρωτοθεραπευόμενων, μη αποκρινόμενων και υποτροπιαζόντων ασθενών που πάσχουν από μόλυνση Ηπατίτιδας HCV.
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US99375307P | 2007-09-14 | 2007-09-14 | |
US99876207P | 2007-10-12 | 2007-10-12 | |
US149407P | 2007-10-30 | 2007-10-30 | |
EP08831728A EP2061513B1 (en) | 2007-09-14 | 2008-09-11 | Method of treating hepatitis c patients |
Publications (1)
Publication Number | Publication Date |
---|---|
CY1112116T1 true CY1112116T1 (el) | 2015-11-04 |
Family
ID=40262964
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CY20111101045T CY1112116T1 (el) | 2007-09-14 | 2011-11-01 | Μεθοδος θεραπειας ασθενων με ηπατιτιδα c |
Country Status (18)
Country | Link |
---|---|
US (1) | US20100226885A1 (el) |
EP (2) | EP2489369A1 (el) |
JP (1) | JP2010539165A (el) |
CN (1) | CN101883590A (el) |
AT (1) | ATE519503T1 (el) |
AU (1) | AU2008301981A1 (el) |
CA (1) | CA2699280A1 (el) |
CY (1) | CY1112116T1 (el) |
DK (1) | DK2061513T3 (el) |
ES (1) | ES2369321T3 (el) |
HK (1) | HK1129315A1 (el) |
HR (1) | HRP20110637T1 (el) |
MX (1) | MX2010002909A (el) |
NZ (1) | NZ583825A (el) |
PL (1) | PL2061513T3 (el) |
PT (1) | PT2061513E (el) |
SI (1) | SI2061513T1 (el) |
WO (1) | WO2009038663A1 (el) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2818853A1 (en) | 2010-11-30 | 2012-06-07 | Gilead Pharmasset Llc | 2'-spirocyclo-nucleosides for use in therapy of hcv or dengue virus |
EP2704570A4 (en) * | 2011-05-04 | 2015-02-18 | Merck Sharp & Dohme | ACTIVE SUBSTANCES, PHARMACEUTICAL COMPOSITIONS AND METHOD FOR THE PRODUCTION THEREOF |
ES2659216T5 (es) | 2011-09-16 | 2021-06-09 | Gilead Pharmasset Llc | Métodos para el tratamiento del VHC |
US8492386B2 (en) | 2011-10-21 | 2013-07-23 | Abbvie Inc. | Methods for treating HCV |
US8853176B2 (en) | 2011-10-21 | 2014-10-07 | Abbvie Inc. | Methods for treating HCV |
PT107925A (pt) | 2011-10-21 | 2014-12-03 | Abbvie Inc | Tratamento de combinação de daa (eg. com abt-072 ou abt-333) para utilização no tratamento de hcv |
US8466159B2 (en) | 2011-10-21 | 2013-06-18 | Abbvie Inc. | Methods for treating HCV |
AU2012332827A1 (en) | 2011-10-31 | 2014-05-15 | Gilead Pharmasset Llc | Methods and compositions for treating hepatitis C virus |
BR112014012739A8 (pt) * | 2011-11-29 | 2017-06-20 | Gilead Pharmasset Llc | composições e métodos para o tratamento do vírus da hepatite c |
US8889159B2 (en) | 2011-11-29 | 2014-11-18 | Gilead Pharmasset Llc | Compositions and methods for treating hepatitis C virus |
EP2809334A4 (en) | 2012-02-01 | 2015-06-24 | Abbvie Inc | ONCE DAILY TREATMENT OF HEPATITIS C WITH RIBAVIRIN AND TARIBAVIRIN |
CN105748499B (zh) | 2013-01-31 | 2018-12-28 | 吉利德制药有限责任公司 | 两个抗病毒化合物的联用制剂 |
CN109689063A (zh) | 2016-04-28 | 2019-04-26 | 埃默里大学 | 含有炔烃的核苷酸和核苷治疗组合物及其相关用途 |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU2157000A (en) * | 1998-12-18 | 2000-07-12 | Schering Corporation | Ribavirin-pegylated interferon alfa induction hcv combination therapy |
US6824768B2 (en) * | 1998-12-18 | 2004-11-30 | Schering Corporation | Ribavirin-pegylated interferon alfa induction HCV combination therapy |
PE20001548A1 (es) * | 1999-03-02 | 2001-01-16 | Schering Corp | Uso de interferon alfa pegilado para el tratamiento de vih-1 |
KR100939155B1 (ko) * | 2000-07-21 | 2010-01-28 | 쉐링 코포레이션 | C형 간염 바이러스의 ns3-세린 프로테아제 억제제로서의신규한 펩티드 |
SV2003000617A (es) | 2000-08-31 | 2003-01-13 | Lilly Co Eli | Inhibidores de la proteasa peptidomimetica ref. x-14912m |
CN101076516A (zh) * | 2004-02-27 | 2007-11-21 | 先灵公司 | 作为丙型肝炎病毒ns3丝氨酸蛋白酶抑制剂的硫化合物 |
WO2006016930A2 (en) * | 2004-05-14 | 2006-02-16 | Intermune, Inc. | Methods for treating hcv infection |
WO2006130553A2 (en) * | 2005-06-02 | 2006-12-07 | Schering Corporation | Hcv protease inhibitors |
EP1981524A2 (en) * | 2006-02-09 | 2008-10-22 | Schering Corporation | Combinations comprising hcv protease inhibitor(s) and hcv polymerase inhibitor(s), and methods of treatment related thereto |
AU2009256623A1 (en) * | 2008-06-10 | 2009-12-17 | Janssen Pharmaceutica Nv | Telaprevir dosing regimen |
-
2008
- 2008-09-11 MX MX2010002909A patent/MX2010002909A/es not_active Application Discontinuation
- 2008-09-11 WO PCT/US2008/010626 patent/WO2009038663A1/en active Application Filing
- 2008-09-11 DK DK08831728.4T patent/DK2061513T3/da active
- 2008-09-11 AU AU2008301981A patent/AU2008301981A1/en not_active Abandoned
- 2008-09-11 US US12/376,180 patent/US20100226885A1/en not_active Abandoned
- 2008-09-11 ES ES08831728T patent/ES2369321T3/es active Active
- 2008-09-11 JP JP2010524864A patent/JP2010539165A/ja active Pending
- 2008-09-11 PT PT08831728T patent/PT2061513E/pt unknown
- 2008-09-11 AT AT08831728T patent/ATE519503T1/de active
- 2008-09-11 CN CN200880116595XA patent/CN101883590A/zh active Pending
- 2008-09-11 NZ NZ583825A patent/NZ583825A/en not_active IP Right Cessation
- 2008-09-11 CA CA2699280A patent/CA2699280A1/en not_active Abandoned
- 2008-09-11 EP EP11176964A patent/EP2489369A1/en not_active Withdrawn
- 2008-09-11 EP EP08831728A patent/EP2061513B1/en not_active Revoked
- 2008-09-11 PL PL08831728T patent/PL2061513T3/pl unknown
- 2008-09-11 SI SI200830406T patent/SI2061513T1/sl unknown
-
2009
- 2009-09-14 HK HK09108390.0A patent/HK1129315A1/xx not_active IP Right Cessation
-
2011
- 2011-09-07 HR HR20110637T patent/HRP20110637T1/hr unknown
- 2011-11-01 CY CY20111101045T patent/CY1112116T1/el unknown
Also Published As
Publication number | Publication date |
---|---|
WO2009038663A1 (en) | 2009-03-26 |
DK2061513T3 (da) | 2011-11-21 |
CA2699280A1 (en) | 2009-03-26 |
PT2061513E (pt) | 2011-10-17 |
MX2010002909A (es) | 2010-03-30 |
ATE519503T1 (de) | 2011-08-15 |
HK1129315A1 (en) | 2009-11-27 |
ES2369321T3 (es) | 2011-11-29 |
NZ583825A (en) | 2012-06-29 |
CN101883590A (zh) | 2010-11-10 |
US20100226885A1 (en) | 2010-09-09 |
EP2061513B1 (en) | 2011-08-10 |
PL2061513T3 (pl) | 2011-12-30 |
EP2489369A1 (en) | 2012-08-22 |
SI2061513T1 (sl) | 2011-11-30 |
AU2008301981A1 (en) | 2009-03-26 |
JP2010539165A (ja) | 2010-12-16 |
HRP20110637T1 (hr) | 2011-10-31 |
EP2061513A1 (en) | 2009-05-27 |
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