CY1108133T1 - Σκευασμα αερολυματος για εισπνοη που περιεχει βρωμιουχο τιοτροπιο - Google Patents
Σκευασμα αερολυματος για εισπνοη που περιεχει βρωμιουχο τιοτροπιοInfo
- Publication number
- CY1108133T1 CY1108133T1 CY20081100623T CY081100623T CY1108133T1 CY 1108133 T1 CY1108133 T1 CY 1108133T1 CY 20081100623 T CY20081100623 T CY 20081100623T CY 081100623 T CY081100623 T CY 081100623T CY 1108133 T1 CY1108133 T1 CY 1108133T1
- Authority
- CY
- Cyprus
- Prior art keywords
- preparation
- tiotropio
- broom
- air
- inhalation containing
- Prior art date
Links
- 244000007853 Sarothamnus scoparius Species 0.000 title 1
- 239000013543 active substance Substances 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- 239000000443 aerosol Substances 0.000 abstract 1
- 208000006673 asthma Diseases 0.000 abstract 1
- 238000009472 formulation Methods 0.000 abstract 1
- 239000003380 propellant Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 238000005507 spraying Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0078—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/5386—1,4-Oxazines, e.g. morpholine spiro-condensed or forming part of bridged ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Pulmonology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Dispersion Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Otolaryngology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Cosmetics (AREA)
- Nozzles (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
Η παρούσα εφεύρεση αφορά ένα σκεύασμα αερολύματος χωρίς προωθητικό αέριο ενός διαλυμένου σε νερό φαρμακευτικά αποδεκτού άλατος του τιοτροπίου. Το σύμφωνα με την εφεύρεση σκεύασμα είναι ιδιαιτέρως κατάλληλο για την εκνέφωση της δραστικής ουσίας με έναν ψεκαστήρα, για τη χορήγηση της δραστικής ουσίας με εισπνοή, κατά προτίμηση όταν υπάρχουν ενδείξεις για άσθμα ή COPD.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10216036A DE10216036A1 (de) | 2002-04-11 | 2002-04-11 | Aerosolformulierung für die Inhalation enthaltend ein Tiotropiumsalz |
| EP03718724A EP1496876B1 (de) | 2002-04-11 | 2003-04-02 | Aerosolformulierung für die inhalation enthaltend tiotropiumbromid |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CY1108133T1 true CY1108133T1 (el) | 2014-02-12 |
Family
ID=28458728
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CY20081100623T CY1108133T1 (el) | 2002-04-11 | 2008-06-11 | Σκευασμα αερολυματος για εισπνοη που περιεχει βρωμιουχο τιοτροπιο |
Country Status (33)
| Country | Link |
|---|---|
| EP (2) | EP1496876B1 (el) |
| JP (1) | JP2005531528A (el) |
| KR (1) | KR100997219B1 (el) |
| CN (1) | CN1309378C (el) |
| AR (1) | AR039286A1 (el) |
| AT (1) | ATE389391T1 (el) |
| AU (1) | AU2003222791B2 (el) |
| BR (1) | BR0309080A (el) |
| CA (1) | CA2473815C (el) |
| CO (1) | CO5611150A2 (el) |
| CY (1) | CY1108133T1 (el) |
| DE (2) | DE10216036A1 (el) |
| DK (1) | DK1496876T3 (el) |
| EA (1) | EA007228B1 (el) |
| EC (1) | ECSP045358A (el) |
| ES (1) | ES2303897T3 (el) |
| HK (1) | HK1078793A1 (el) |
| HR (1) | HRP20040932B1 (el) |
| ME (1) | ME00359B (el) |
| MX (1) | MXPA04009818A (el) |
| MY (1) | MY137249A (el) |
| NO (1) | NO334915B1 (el) |
| PE (1) | PE20030970A1 (el) |
| PL (1) | PL371204A1 (el) |
| PT (1) | PT1496876E (el) |
| RS (1) | RS50923B (el) |
| SA (1) | SA03240192B1 (el) |
| SI (1) | SI1496876T1 (el) |
| TW (1) | TWI344851B (el) |
| UA (1) | UA78994C2 (el) |
| UY (1) | UY27754A1 (el) |
| WO (1) | WO2003084519A2 (el) |
| ZA (1) | ZA200405721B (el) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PT2067779E (pt) | 2003-11-03 | 2013-07-25 | Boehringer Ingelheim Int | Sais de tiotrópio, processo para a sua preparação e formulações de produtos farmacêuticos contendo os mesmos |
| EP1915158A1 (en) * | 2005-08-06 | 2008-04-30 | Boehringer Ingelheim International GmbH | Use of tiotropium salts in the treatment of severe persistant asthma |
| TWI389692B (zh) | 2005-10-10 | 2013-03-21 | Boehringer Ingelheim Int | 用以吸入β-共效劑的氣溶膠調配物 |
| EP1905440A1 (de) * | 2006-09-06 | 2008-04-02 | Boehringer Ingelheim Pharma GmbH & Co. KG | Verwendung einer pharmazeutischen Zusammensetzung enthaltend ein Anticholinergikum zur Abtötung von Mikroorganismen und zur Behandlung von Atemwegsinfektionen |
| EP2044967A1 (de) * | 2007-10-01 | 2009-04-08 | Boehringer Ingelheim Pharma GmbH & Co. KG | Zerstäuber |
| WO2013127738A1 (de) | 2012-02-28 | 2013-09-06 | Boehringer Ingelheim International Gmbh | Neue treibgashaltige tiotropium-formulierung |
| RU2493827C1 (ru) * | 2012-10-03 | 2013-09-27 | Шолекс Девелопмент Гмбх | Стабильный комбинированный раствор фенотерола гидробромида и ипратропия бромида |
| WO2015065223A1 (ru) * | 2013-10-28 | 2015-05-07 | Шолекс Девелопмент Гмбх | Стабильный раствор фенотерола гидробромида |
| WO2015065219A1 (ru) * | 2013-10-28 | 2015-05-07 | Шолекс Девелопмент Гмбх | Раствор ипратропия бромида |
| GB201507686D0 (en) * | 2015-05-05 | 2015-06-17 | Norton Healthcare Ltd | A stable tiotropium nebuliser solution |
| EA201990606A1 (ru) * | 2016-11-16 | 2019-10-31 | Распыляемый тиотропий | |
| CN115209872B (zh) * | 2020-03-19 | 2024-08-02 | 广州谷森制药有限公司 | 含有酒石酸左旋沙丁胺醇的可吸入制剂 |
| CN114259481A (zh) * | 2021-11-26 | 2022-04-01 | 南京华盖制药有限公司 | 一种奥达特罗复方吸入溶液 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3931041C2 (de) | 1989-09-16 | 2000-04-06 | Boehringer Ingelheim Kg | Ester von Thienylcarbonsäuren mit Aminoalkoholen, ihre Quaternierungsprodukte, Verfahren zu ihrer Herstellung und diese enthaltende Arzneimittel |
| SG45171A1 (en) | 1990-03-21 | 1998-01-16 | Boehringer Ingelheim Int | Atomising devices and methods |
| IL107120A (en) | 1992-09-29 | 1997-09-30 | Boehringer Ingelheim Int | Atomising nozzle and filter and spray generating device |
| DE19536903C2 (de) | 1995-10-04 | 1998-09-10 | Boehringer Ingelheim Int | Vorrichtung zum Haltern eines fluidischen Bauteils |
| DE19536902A1 (de) | 1995-10-04 | 1997-04-10 | Boehringer Ingelheim Int | Vorrichtung zur Hochdruckerzeugung in einem Fluid in Miniaturausführung |
| DE19545226C1 (de) | 1995-12-05 | 1997-06-19 | Boehringer Ingelheim Int | Sperrspannwerk für einen federbetätigten Abtrieb |
| DE19653969A1 (de) | 1996-12-20 | 1998-06-25 | Boehringer Ingelheim Kg | Neue wässrige Arzneimittelzubereitung zur Erzeugung treibgasfreier Aerosole |
| DE19742439C1 (de) | 1997-09-26 | 1998-10-22 | Boehringer Ingelheim Int | Mikrostrukturiertes Filter |
| DE19847968A1 (de) * | 1998-10-17 | 2000-04-20 | Boehringer Ingelheim Pharma | Verschlußkappe und Behälter als Zweikammer-Kartusche für Vernebler zur Erzeugung von Aerosolen |
| SI1333819T1 (sl) * | 2000-10-31 | 2007-12-31 | Boehringer Ingelheim Pharma | Inhalacijska formulacija v raztopini s tiotropijevo soljo |
-
2002
- 2002-04-11 DE DE10216036A patent/DE10216036A1/de not_active Withdrawn
-
2003
- 2003-02-04 UA UA20041109194A patent/UA78994C2/uk unknown
- 2003-04-02 DE DE50309414T patent/DE50309414D1/de not_active Expired - Lifetime
- 2003-04-02 ME MEP-2008-543A patent/ME00359B/me unknown
- 2003-04-02 DK DK03718724T patent/DK1496876T3/da active
- 2003-04-02 PT PT03718724T patent/PT1496876E/pt unknown
- 2003-04-02 AT AT03718724T patent/ATE389391T1/de active
- 2003-04-02 MX MXPA04009818A patent/MXPA04009818A/es active IP Right Grant
- 2003-04-02 SI SI200331206T patent/SI1496876T1/sl unknown
- 2003-04-02 ES ES03718724T patent/ES2303897T3/es not_active Expired - Lifetime
- 2003-04-02 EP EP03718724A patent/EP1496876B1/de not_active Expired - Lifetime
- 2003-04-02 EA EA200401305A patent/EA007228B1/ru not_active IP Right Cessation
- 2003-04-02 AU AU2003222791A patent/AU2003222791B2/en not_active Expired
- 2003-04-02 WO PCT/EP2003/003438 patent/WO2003084519A2/de active IP Right Grant
- 2003-04-02 CA CA2473815A patent/CA2473815C/en not_active Expired - Fee Related
- 2003-04-02 EP EP08152138A patent/EP1949892A1/de not_active Withdrawn
- 2003-04-02 CN CNB038082330A patent/CN1309378C/zh not_active Ceased
- 2003-04-02 JP JP2003581759A patent/JP2005531528A/ja active Pending
- 2003-04-02 RS YUP-879/04A patent/RS50923B/sr unknown
- 2003-04-02 BR BR0309080-9A patent/BR0309080A/pt active Pending
- 2003-04-02 KR KR1020047016052A patent/KR100997219B1/ko active IP Right Grant
- 2003-04-02 PL PL03371204A patent/PL371204A1/xx not_active Application Discontinuation
- 2003-04-09 MY MYPI20031314A patent/MY137249A/en unknown
- 2003-04-09 UY UY27754A patent/UY27754A1/es not_active Application Discontinuation
- 2003-04-09 PE PE2003000359A patent/PE20030970A1/es not_active Application Discontinuation
- 2003-04-10 TW TW092108240A patent/TWI344851B/zh not_active IP Right Cessation
- 2003-04-11 AR ARP030101267A patent/AR039286A1/es active Pending
- 2003-07-07 SA SA03240192A patent/SA03240192B1/ar unknown
-
2004
- 2004-07-19 ZA ZA200405721A patent/ZA200405721B/en unknown
- 2004-09-23 NO NO20044001A patent/NO334915B1/no not_active IP Right Cessation
- 2004-10-07 HR HRP20040932AA patent/HRP20040932B1/hr not_active IP Right Cessation
- 2004-10-08 CO CO04100971A patent/CO5611150A2/es active IP Right Grant
- 2004-10-11 EC EC2004005358A patent/ECSP045358A/es unknown
-
2005
- 2005-12-01 HK HK05110950A patent/HK1078793A1/xx not_active IP Right Cessation
-
2008
- 2008-06-11 CY CY20081100623T patent/CY1108133T1/el unknown
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