CY1106180T1 - Σκευασματα διασπορας τα οποια πepιεχουν αναστολεις λιπασης - Google Patents
Σκευασματα διασπορας τα οποια πepιεχουν αναστολεις λιπασηςInfo
- Publication number
- CY1106180T1 CY1106180T1 CY20061101416T CY061101416T CY1106180T1 CY 1106180 T1 CY1106180 T1 CY 1106180T1 CY 20061101416 T CY20061101416 T CY 20061101416T CY 061101416 T CY061101416 T CY 061101416T CY 1106180 T1 CY1106180 T1 CY 1106180T1
- Authority
- CY
- Cyprus
- Prior art keywords
- inhibitors
- dispersions containing
- containing lipstick
- lipstick
- inhibitor
- Prior art date
Links
- 239000003112 inhibitor Substances 0.000 title abstract 2
- 239000006185 dispersion Substances 0.000 title 1
- 229940086609 Lipase inhibitor Drugs 0.000 abstract 1
- 102000019280 Pancreatic lipases Human genes 0.000 abstract 1
- 108050006759 Pancreatic lipases Proteins 0.000 abstract 1
- 239000002270 dispersing agent Substances 0.000 abstract 1
- 230000002496 gastric effect Effects 0.000 abstract 1
- AHLBNYSZXLDEJQ-FWEHEUNISA-N orlistat Chemical compound CCCCCCCCCCC[C@H](OC(=O)[C@H](CC(C)C)NC=O)C[C@@H]1OC(=O)[C@H]1CCCCCC AHLBNYSZXLDEJQ-FWEHEUNISA-N 0.000 abstract 1
- 229960001243 orlistat Drugs 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 239000004094 surface-active agent Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
- A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/485—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4858—Organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
- A61K9/0007—Effervescent
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Dispersion Chemistry (AREA)
- Diabetes (AREA)
- Obesity (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Hematology (AREA)
- Inorganic Chemistry (AREA)
- Child & Adolescent Psychology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
Η παρούσα εφεύρεση σχετίζεται με μία φαρμακευτική σύνθεση η οποία περιλαμβάνει τουλάχιστον έναν αναστολέα λιπασών, κατά προτίμηση έναν αναστολέα γαστρεντερικών και παγκρεατικών λιπασών, π.χ. ορλιστάτη, και τουλάχιστον ένα τασιενεργό και τουλάχιστον έναν παράγοντα διασποράς.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP99118180 | 1999-09-13 | ||
PCT/EP2000/008858 WO2001019340A1 (en) | 1999-09-13 | 2000-09-11 | Dispersion formulations containing lipase inhibitors |
EP00960643A EP1216025B1 (en) | 1999-09-13 | 2000-09-11 | Dispersion formulations containing lipase inhibitors |
Publications (1)
Publication Number | Publication Date |
---|---|
CY1106180T1 true CY1106180T1 (el) | 2011-06-08 |
Family
ID=8238990
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CY20061101416T CY1106180T1 (el) | 1999-09-13 | 2006-09-29 | Σκευασματα διασπορας τα οποια πepιεχουν αναστολεις λιπασης |
Country Status (39)
Country | Link |
---|---|
US (3) | US20030181512A1 (el) |
EP (1) | EP1216025B1 (el) |
JP (1) | JP4217016B2 (el) |
KR (1) | KR100572434B1 (el) |
CN (1) | CN1197551C (el) |
AR (1) | AR025587A1 (el) |
AT (1) | ATE333866T1 (el) |
AU (1) | AU769415B2 (el) |
BR (2) | BRPI0013939B1 (el) |
CA (1) | CA2383916C (el) |
CO (1) | CO5180587A1 (el) |
CY (1) | CY1106180T1 (el) |
CZ (1) | CZ301901B6 (el) |
DE (1) | DE60029602T2 (el) |
DK (1) | DK1216025T3 (el) |
EG (1) | EG24117A (el) |
ES (1) | ES2267563T3 (el) |
HK (1) | HK1049966A1 (el) |
HR (1) | HRP20020205B1 (el) |
HU (1) | HU228858B1 (el) |
IL (1) | IL148494A0 (el) |
JO (1) | JO2386B1 (el) |
MA (1) | MA26818A1 (el) |
ME (1) | MEP90808A (el) |
MX (1) | MXPA02002034A (el) |
MY (1) | MY130200A (el) |
NO (1) | NO331906B1 (el) |
NZ (1) | NZ517545A (el) |
PE (1) | PE20010595A1 (el) |
PL (1) | PL199870B1 (el) |
PT (1) | PT1216025E (el) |
RS (1) | RS50422B (el) |
RU (1) | RU2239428C2 (el) |
SI (1) | SI1216025T1 (el) |
TR (1) | TR200200606T2 (el) |
TW (1) | TWI243060B (el) |
UY (1) | UY26338A1 (el) |
WO (1) | WO2001019340A1 (el) |
ZA (1) | ZA200201518B (el) |
Families Citing this family (26)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
PL204443B1 (pl) * | 2000-07-28 | 2010-01-29 | Hoffmann La Roche | Kompozycja farmaceutyczna zawierająca inhibitor lipazy, sposób wytwarzania kompozycji farmaceutycznej, zestaw do leczenia otyłości, zastosowanie kompozycji farmaceutycznej oraz zastosowanie orlistatu i substancji wiążącej kwasy żółciowe |
US6730319B2 (en) * | 2001-06-06 | 2004-05-04 | Hoffmann-La Roche Inc. | Pharmaceutical compositions having depressed melting points |
US20030027786A1 (en) | 2001-06-06 | 2003-02-06 | Karsten Maeder | Lipase inhibiting composition |
US8372430B2 (en) * | 2002-12-17 | 2013-02-12 | The Procter & Gamble Company | Compositions, methods, and kits useful for the alleviation of gastrointestinal effects |
FI20045076A (fi) * | 2004-03-15 | 2005-09-16 | Bioferme Oy | Funktionaalinen elintarvike |
WO2006113505A2 (en) * | 2005-04-15 | 2006-10-26 | Clarus Therapeutics, Inc. | Pharmaceutical delivery systems for hydrophobic drugs and compositions comprising same |
KR100910000B1 (ko) * | 2005-05-13 | 2009-07-29 | 씨제이제일제당 (주) | 리파아제 저해제 함유 약학 조성물 |
PT1897558E (pt) * | 2005-06-09 | 2013-11-06 | Norgine Bv | Preparação sólida de 2-hexadeciloxi-6-metil-4h-3,1- benzoxazin-4-ona |
KR100669497B1 (ko) * | 2005-08-17 | 2007-01-16 | 보람제약주식회사 | 안정성과 용출률이 뛰어난 약리학적 조성물 및 그 제조방법 |
WO2007033522A1 (fr) * | 2005-09-21 | 2007-03-29 | Shenzhen Tys R & D Co., Ltd. | Formulation de gélule contenant de la moxifloxacine et son procédé de préparation |
KR101252635B1 (ko) * | 2006-04-20 | 2013-04-10 | (주)아모레퍼시픽 | 리파아제 저해제 및 친유성 오일흡수제를 포함하는 약학조성물 및 이로부터 제조된 경구 투여용 제제 |
TR200607613A2 (tr) * | 2006-12-29 | 2008-07-21 | NOBEL İLAÇ SAN.ve TiC.A.Ş. | Lipaz inhibitörü içeren farmasötik formülasyonlar |
EP1970051A1 (en) * | 2007-03-14 | 2008-09-17 | Merz Pharma GmbH & Co.KGaA | Use of an aqueous micro-emulsion for the preparation of a formulation for the treatment of adipose diseases |
KR101439470B1 (ko) * | 2007-05-22 | 2014-09-16 | 한미사이언스 주식회사 | 오를리스타트 및 대변 연화제를 포함하는 비만의 예방 또는치료용 조성물 |
ES2350798T3 (es) * | 2007-09-12 | 2011-01-27 | Mader S.R.L. | Composiciones farmacéuticas para uso oral para tratar a pacientes afectados por la obesidad. |
EP2044930A1 (en) * | 2007-10-01 | 2009-04-08 | Nestec S.A. | Composition for controlling lipase catalyzed reactions |
PL216542B1 (pl) | 2008-03-20 | 2014-04-30 | Zakłady Farmaceutyczne POLPHARMA Spółka Akcyjna | Sposób wytwarzania stabilnej kompozycji orlistatu w postaci kapsułkowanego proszku |
WO2010042499A1 (en) * | 2008-10-06 | 2010-04-15 | Banner Pharmacaps, Inc. | Stable solutions of orlistat for pharmaceutical dosage forms |
KR20100075260A (ko) * | 2008-12-24 | 2010-07-02 | 주식회사종근당 | 리파아제 저해제의 부작용 개선을 위한 신규한 약제학적 조성물 |
BRPI0901602B8 (pt) | 2009-04-03 | 2021-05-25 | Ems S/A | formulação farmacêuticas |
ITRM20120331A1 (it) | 2012-07-12 | 2014-01-13 | Guidotti & C Spa Labor | Composizioni pediatriche orali liquide contenenti nepadutant. |
BR112017021995A2 (pt) * | 2015-04-14 | 2018-07-10 | Zim Laboratories Ltd | formulação farmacêutica compreendendo drogas de baixa fusão e altamente lipofílicas e método de melhora da dissolução |
CN106310287B (zh) * | 2015-06-25 | 2019-03-19 | 山东省药学科学院 | 新利司他药用组合物及其制备方法 |
MY196635A (en) * | 2018-06-22 | 2023-04-25 | Sime Darby Plantation Intellectual Property Sdn Bhd | Method For Reducing Formation of Free Fatty Acids in Plants |
CN115105476B (zh) * | 2021-03-23 | 2023-11-14 | 山东新时代药业有限公司 | 一种奥利司他冻干口服制剂及其制备工艺 |
CN114983938A (zh) * | 2022-05-19 | 2022-09-02 | 广东嘉博制药有限公司 | 一种奥利司他口服复合乳液及其制备方法 |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA1247547A (en) * | 1983-06-22 | 1988-12-28 | Paul Hadvary | Leucine derivatives |
EP0281200B1 (en) * | 1987-03-02 | 1994-01-19 | Yamanouchi Europe B.V. | Pharmaceutical composition, pharmaceutical granulate and process for their preparation |
CA2128044C (en) * | 1993-08-05 | 2007-02-20 | Klaus-Dieter Bremer | Pharmaceutical compositions comprising a glucosidase and/or amylase inhibitor, and a lipase inhibitor |
IT1282673B1 (it) | 1996-02-23 | 1998-03-31 | Ist Naz Stud Cura Dei Tumori | Derivati della camptotecina e loro uso come agenti antitumorali |
CA2264718C (en) | 1996-09-01 | 2006-05-30 | Pharmos Corporation | Solid coprecipitates for enhanced bioavailability of lipophilic substances |
US5891469A (en) * | 1997-04-02 | 1999-04-06 | Pharmos Corporation | Solid Coprecipitates for enhanced bioavailability of lipophilic substances |
US6004996A (en) * | 1997-02-05 | 1999-12-21 | Hoffman-La Roche Inc. | Tetrahydrolipstatin containing compositions |
KR100479968B1 (ko) * | 1997-02-05 | 2005-03-30 | 에프. 호프만-라 로슈 아게 | 위장 리파아제 억제제의 용도 |
US6267952B1 (en) | 1998-01-09 | 2001-07-31 | Geltex Pharmaceuticals, Inc. | Lipase inhibiting polymers |
AU759388B2 (en) | 1998-08-14 | 2003-04-10 | Cheplapharm Arzneimittel Gmbh | Pharmaceutical compositions containing lipase inhibitors and chitosan |
KR20010079635A (ko) | 1998-08-14 | 2001-08-22 | 프리돌린 클라우스너, 롤란드 비. 보레르 | 리파아제 저해제를 함유하는 약학 조성물 |
US6368622B2 (en) * | 1999-01-29 | 2002-04-09 | Abbott Laboratories | Process for preparing solid formulations of lipid regulating agents with enhanced dissolution and absorption |
-
2000
- 2000-09-07 AR ARP000104679A patent/AR025587A1/es not_active Application Discontinuation
- 2000-09-11 MX MXPA02002034A patent/MXPA02002034A/es active IP Right Grant
- 2000-09-11 SI SI200030888T patent/SI1216025T1/sl unknown
- 2000-09-11 BR BRPI0013939-4A patent/BRPI0013939B1/pt unknown
- 2000-09-11 TR TR2002/00606T patent/TR200200606T2/xx unknown
- 2000-09-11 CN CNB008126801A patent/CN1197551C/zh not_active Expired - Lifetime
- 2000-09-11 CZ CZ20021276A patent/CZ301901B6/cs not_active IP Right Cessation
- 2000-09-11 CA CA002383916A patent/CA2383916C/en not_active Expired - Lifetime
- 2000-09-11 EP EP00960643A patent/EP1216025B1/en not_active Expired - Lifetime
- 2000-09-11 ES ES00960643T patent/ES2267563T3/es not_active Expired - Lifetime
- 2000-09-11 WO PCT/EP2000/008858 patent/WO2001019340A1/en active IP Right Grant
- 2000-09-11 HU HU0202737A patent/HU228858B1/hu unknown
- 2000-09-11 DK DK00960643T patent/DK1216025T3/da active
- 2000-09-11 DE DE60029602T patent/DE60029602T2/de not_active Expired - Lifetime
- 2000-09-11 NZ NZ517545A patent/NZ517545A/en not_active IP Right Cessation
- 2000-09-11 AU AU72863/00A patent/AU769415B2/en not_active Expired
- 2000-09-11 KR KR1020027003269A patent/KR100572434B1/ko active IP Right Grant
- 2000-09-11 AT AT00960643T patent/ATE333866T1/de active
- 2000-09-11 RS YUP-172/02A patent/RS50422B/sr unknown
- 2000-09-11 BR BR0013939-4A patent/BR0013939A/pt not_active IP Right Cessation
- 2000-09-11 IL IL14849400A patent/IL148494A0/xx active IP Right Grant
- 2000-09-11 PL PL356174A patent/PL199870B1/pl unknown
- 2000-09-11 RU RU2002107428/15A patent/RU2239428C2/ru active
- 2000-09-11 ME MEP-908/08A patent/MEP90808A/xx unknown
- 2000-09-11 JP JP2001522975A patent/JP4217016B2/ja not_active Expired - Lifetime
- 2000-09-11 PT PT00960643T patent/PT1216025E/pt unknown
- 2000-09-12 EG EG20001159A patent/EG24117A/xx active
- 2000-09-12 JO JO2000157A patent/JO2386B1/en active
- 2000-09-12 UY UY26338A patent/UY26338A1/es not_active Application Discontinuation
- 2000-09-12 CO CO00068859A patent/CO5180587A1/es active IP Right Grant
- 2000-09-13 PE PE2000000949A patent/PE20010595A1/es not_active IP Right Cessation
- 2000-09-13 MY MYPI20004253A patent/MY130200A/en unknown
- 2000-10-19 TW TW089121968A patent/TWI243060B/zh not_active IP Right Cessation
-
2002
- 2002-02-22 ZA ZA200201518A patent/ZA200201518B/xx unknown
- 2002-03-07 HR HR20020205A patent/HRP20020205B1/xx not_active IP Right Cessation
- 2002-03-11 MA MA26545A patent/MA26818A1/fr unknown
- 2002-03-12 NO NO20021204A patent/NO331906B1/no not_active IP Right Cessation
-
2003
- 2003-03-25 HK HK03102148A patent/HK1049966A1/xx not_active IP Right Cessation
- 2003-04-21 US US10/419,346 patent/US20030181512A1/en not_active Abandoned
-
2004
- 2004-03-05 US US10/794,123 patent/US8012494B2/en not_active Expired - Lifetime
-
2006
- 2006-09-29 CY CY20061101416T patent/CY1106180T1/el unknown
-
2011
- 2011-07-19 US US13/185,558 patent/US20110275706A1/en not_active Abandoned
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