CU20090048A7 - Nuevos derivados de diosmetina, su procedimiento de preparación y las composiciones farmacéuticas que los contienen - Google Patents
Nuevos derivados de diosmetina, su procedimiento de preparación y las composiciones farmacéuticas que los contienenInfo
- Publication number
- CU20090048A7 CU20090048A7 CU20090048A CU20090048A CU20090048A7 CU 20090048 A7 CU20090048 A7 CU 20090048A7 CU 20090048 A CU20090048 A CU 20090048A CU 20090048 A CU20090048 A CU 20090048A CU 20090048 A7 CU20090048 A7 CU 20090048A7
- Authority
- CU
- Cuba
- Prior art keywords
- diosmetine
- pharmaceutical compositions
- compositions containing
- preparation procedure
- new derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
- C07D311/26—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3
- C07D311/28—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 2 only
- C07D311/30—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 2 only not hydrogenated in the hetero ring, e.g. flavones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
- C07D311/26—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3
- C07D311/28—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 2 only
- C07D311/32—2,3-Dihydro derivatives, e.g. flavanones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/06—Free radical scavengers or antioxidants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
- C07D311/26—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3
- C07D311/28—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 2 only
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
- C07D407/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/203—Monocyclic carbocyclic rings other than cyclohexane rings; Bicyclic carbocyclic ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
- C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
- C07H17/06—Benzopyran radicals
- C07H17/065—Benzo[b]pyrans
- C07H17/07—Benzo[b]pyran-4-ones
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Obesity (AREA)
- Heart & Thoracic Surgery (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Cardiology (AREA)
- Vascular Medicine (AREA)
- Child & Adolescent Psychology (AREA)
- Urology & Nephrology (AREA)
- Rheumatology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Endocrinology (AREA)
- Dermatology (AREA)
- Emergency Medicine (AREA)
- Pain & Pain Management (AREA)
- Toxicology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Saccharide Compounds (AREA)
Abstract
Compuesto de fórmula (I) ESPACIO PARA FÓRMULA I en la que R1, R2 y R3, idénticos o diferentes, presentan cada uno un átomo de hidrógeno o el grupo de fórmula (A): ESPACIO PARA FÓRMULA A
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0801779A FR2929276B1 (fr) | 2008-04-01 | 2008-04-01 | Nouveaux derives de diosmetine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CU20090048A7 true CU20090048A7 (es) | 2011-03-21 |
| CU23761B7 CU23761B7 (es) | 2012-01-31 |
Family
ID=39809617
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CU20090048A CU23761B7 (es) | 2008-04-01 | 2009-03-26 | Nuevos derivados de diosmetina, su procedimiento de preparación y las composiciones farmacéuticas que los contienen |
Country Status (48)
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2002835A1 (en) | 2007-06-04 | 2008-12-17 | GenKyo Tex | Pyrazolo pyridine derivatives as NADPH oxidase inhibitors |
| EP2166010A1 (en) | 2008-09-23 | 2010-03-24 | Genkyo Tex Sa | Pyrazolo pyridine derivatives as NADPH oxidase inhibitors |
| EP2165707A1 (en) | 2008-09-23 | 2010-03-24 | Genkyo Tex Sa | Pyrazolo pyridine derivatives as NADPH oxidase inhibitors |
| EP2166009A1 (en) | 2008-09-23 | 2010-03-24 | Genkyo Tex Sa | Pyrazolo pyridine derivatives as nadph oxidase inhibitors |
| EP2305679A1 (en) | 2009-09-28 | 2011-04-06 | GenKyoTex SA | Pyrazoline dione derivatives as nadph oxidase inhibitors |
| FR3002543A1 (fr) * | 2013-02-28 | 2014-08-29 | Servier Lab | Procede de synthese enzymatique de flavonoides, et application a la synthese de derives de diosmetine |
| CN106031723A (zh) * | 2015-09-29 | 2016-10-19 | 西南大学 | 香叶木素的抗炎活性及其制剂应用 |
| CN106822087A (zh) * | 2017-01-12 | 2017-06-13 | 西南大学 | 香叶木素在制备治疗ⅱ型糖尿病的药物中的应用 |
| CA3062185A1 (en) * | 2017-05-04 | 2018-11-08 | Glenmark Pharmaceuticals S.A. | Substituted bicyclic heterocyclic compounds as nadph oxidase inhibitors |
| HRP20231517T1 (hr) | 2017-07-19 | 2024-03-01 | Primus Pharmaceuticals, Inc. | Postupci liječenja autoimunih mikrovaskularnih poremećaja |
| CN109280067B (zh) * | 2017-07-21 | 2022-07-05 | 南京正大天晴制药有限公司 | 香叶木苷衍生物、其制备方法以及医药用途 |
| EP3700334A4 (en) * | 2017-10-27 | 2021-07-21 | Transfusion Health, LLC | COMPOSITIONS AND PROCESSES FOR THE PRODUCTION OF EXPANDED HEMATOPOIETIC STEM CELLS USING FLUORENE DERIVATIVES |
| EP3479843A1 (en) | 2017-11-01 | 2019-05-08 | GenKyoTex Suisse SA | Use of nox inhibitors for treatment of cancer |
| CN109394753B (zh) * | 2018-12-24 | 2020-10-02 | 武汉轻工大学 | 香叶木素在制备预防和/或治疗高尿酸血症肾病的药物中的应用 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2701261B1 (fr) * | 1993-02-05 | 1995-03-31 | Adir | Nouveaux composés glucuronides de la diosmétine, leur procédé de préparation et les compositions pharmaceutiques les renfermant. |
| FR2726273B1 (fr) * | 1994-10-26 | 1996-12-06 | Adir | Nouveaux derives de la diosmetine, leur procede de preparation et les compositions pharmaceutiques les contenant |
| FR2748025B1 (fr) * | 1996-04-25 | 1998-10-30 | Adir | Nouveaux acides et esters de la diosmetine, et les compositions pharmaceutiques les contenant |
| PL343419A1 (en) * | 1998-03-12 | 2001-08-13 | Microbial Chem Res Found | Benzofurylpyrone derivatives |
| GB9920912D0 (en) * | 1999-09-03 | 1999-11-10 | Indena Spa | Novel derivatives of flavones,xanthones and coumarins |
| FR2882654B1 (fr) * | 2005-03-01 | 2007-04-27 | Servier Lab | Utilisation de derives de la diosmetine pour le traitement et la prevention des pathologies thrombotiques |
-
2008
- 2008-04-01 FR FR0801779A patent/FR2929276B1/fr not_active Expired - Fee Related
-
2009
- 2009-03-12 PE PE2009000365A patent/PE20091692A1/es active IP Right Grant
- 2009-03-12 SG SG200901706-2A patent/SG155849A1/en unknown
- 2009-03-13 UY UY31712A patent/UY31712A1/es active IP Right Grant
- 2009-03-13 MY MYPI20091038A patent/MY144726A/en unknown
- 2009-03-17 JO JO2009107A patent/JO2673B1/en active
- 2009-03-17 IL IL197638A patent/IL197638A/en active IP Right Grant
- 2009-03-17 AU AU2009201068A patent/AU2009201068B2/en active Active
- 2009-03-17 CR CR10665A patent/CR10665A/es unknown
- 2009-03-18 GT GT200900062A patent/GT200900062A/es unknown
- 2009-03-19 ZA ZA2009/01947A patent/ZA200901947B/en unknown
- 2009-03-20 CO CO09029385A patent/CO6150038A1/es active IP Right Grant
- 2009-03-23 AP AP2009004810A patent/AP3024A/xx active
- 2009-03-25 GE GEAP200911185A patent/GEP20115342B/en unknown
- 2009-03-26 CU CU20090048A patent/CU23761B7/es active IP Right Grant
- 2009-03-27 CN CN2009101324295A patent/CN101550124B/zh active Active
- 2009-03-27 CL CL2009000757A patent/CL2009000757A1/es unknown
- 2009-03-27 UA UAA200902916A patent/UA98623C2/ru unknown
- 2009-03-30 MA MA31742A patent/MA31413B1/fr unknown
- 2009-03-30 SA SA109300201A patent/SA109300201B1/ar unknown
- 2009-03-30 US US12/383,888 patent/US8138223B2/en active Active
- 2009-03-30 HN HN2009000566A patent/HN2009000566A/es unknown
- 2009-03-30 EC EC2009009216A patent/ECSP099216A/es unknown
- 2009-03-30 NZ NZ575902A patent/NZ575902A/en unknown
- 2009-03-30 MX MX2009003383A patent/MX2009003383A/es active IP Right Grant
- 2009-03-30 SV SV2009003199A patent/SV2009003199A/es unknown
- 2009-03-31 WO PCT/FR2009/000371 patent/WO2009133269A1/fr active Application Filing
- 2009-03-31 PT PT09290237T patent/PT2107055E/pt unknown
- 2009-03-31 DE DE602009000873T patent/DE602009000873D1/de active Active
- 2009-03-31 NI NI200900042A patent/NI200900042A/es unknown
- 2009-03-31 ES ES09290237T patent/ES2363196T3/es active Active
- 2009-03-31 DK DK09290237.8T patent/DK2107055T3/da active
- 2009-03-31 JP JP2009084080A patent/JP5047211B2/ja active Active
- 2009-03-31 PL PL09290237T patent/PL2107055T3/pl unknown
- 2009-03-31 CA CA2659947A patent/CA2659947C/fr active Active
- 2009-03-31 TW TW098110698A patent/TWI385178B/zh not_active IP Right Cessation
- 2009-03-31 AR ARP090101138A patent/AR071120A1/es active IP Right Grant
- 2009-03-31 EA EA200900397A patent/EA015424B1/ru unknown
- 2009-03-31 BR BRPI0900983A patent/BRPI0900983B8/pt active IP Right Grant
- 2009-03-31 EP EP09290237A patent/EP2107055B1/fr active Active
- 2009-03-31 ME MEP-2009-109A patent/ME00680B/me unknown
- 2009-03-31 RS RS20110142A patent/RS51661B/en unknown
- 2009-03-31 AT AT09290237T patent/ATE502024T1/de active
- 2009-03-31 SI SI200930019T patent/SI2107055T1/sl unknown
-
2010
- 2010-03-29 HK HK10103244.6A patent/HK1136291A1/xx not_active IP Right Cessation
-
2011
- 2011-03-22 CY CY20111100344T patent/CY1111367T1/el unknown
- 2011-05-16 HR HR20110361T patent/HRP20110361T1/hr unknown
-
2012
- 2012-02-14 US US13/372,811 patent/US8404742B2/en active Active
- 2012-04-16 KR KR1020120039373A patent/KR20120049855A/ko not_active Application Discontinuation
-
2017
- 2017-09-28 AR ARP170102686A patent/AR109739A2/es not_active Application Discontinuation
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CU20090048A7 (es) | Nuevos derivados de diosmetina, su procedimiento de preparación y las composiciones farmacéuticas que los contienen | |
| CO6321282A2 (es) | Derivados de piperidinilindol como inhibidores de aldosterona sintasa | |
| CU20110204A7 (es) | Compuestos 1-cianoetilheterociclilcarboxamida sustituidos 750 | |
| ECSP12011910A (es) | Derivados de imidazopiridina como inhibidores de jak | |
| ECSP12011867A (es) | Derivados bencimidazol-imidazol | |
| CR20110028A (es) | Derivados de pirimidina como inhibidores de cinasa | |
| CR20110484A (es) | Nuevos derivados de benzotiazepinas su procedimiento de preparacion y composiciones farmaceuticas que los contienen | |
| CR11857A (es) | Compuestos pirazolicos 436 | |
| BR112014006660A2 (pt) | novos derivados de dihidroquinolina-2-ona bicíclicos | |
| UY31481A1 (es) | Nuevos derivados de pirimidina, procesos de preparacion, composiciones farmacéuticas conteniéndolos y aplicaciones | |
| ECSP14013245A (es) | Nuevos derivados dihidroquinolina-2-ona | |
| AR088226A1 (es) | Derivados piperidinicos heterociclicos, composiciones farmaceuticas que los contienen y uso de los mismos para el tratamiento de enfermedades neurodegenerativas | |
| UY31906A (es) | Derivados de n-cicloalquil-3-fenilnicotinamida que inhiben pgds, sus composiciones, su uso para el tratamiento por ejemplo de afecciones alérgicas y respiratorias. | |
| CR20140135A (es) | Nuevos derivados de aril-quinolina | |
| CU20100157A7 (es) | Nuevos derivados dihidroindolonas, su procedimiento de preparación y las composiciones farmacéuticas que los contienen | |
| UY31905A (es) | Derivados de benzoxazinona, procesos de preparación, composiciones farmacéuticas conteniéndolos y aplicaciones. | |
| UY32635A (es) | Derivados de bis-(sulfonilamino) en terapia 735 | |
| ECSP099679A (es) | Nuevos compuestos y sus usos 707 | |
| CU20120041A7 (es) | Nuevos derivados dihidro-oxazolobenzodiazepinonas, su procedimiento de preparación y las composiciones farmacéuticas que los contienen | |
| CU20130037A7 (es) | Nuevos derivados dihidrobenzoxatiazepinas, su procedimiento de preparación y las composiciones farmacéuticas que los contienen | |
| UY32702A (es) | Nuevos derivados de ácido 2-mercaptociclopentanocarboxílico, su procedimiento de preparación y las composiciones farmacéuticas que los contienen. | |
| SV2010003626A (es) | Nuevos compuestos piperidinicos, su procedimiento de preparacion y las composiciones farmaceuticas que los contienen | |
| UY30343A1 (es) | Derivados de 1,2,3,4-tetrahidro-quinolina como inhibidores de cetp | |
| CU20100250A7 (es) | Compuestos pirazólicos 436 | |
| CU23617A3 (es) | Nuevos derivados de quinolina |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant of patent |