CS221405B1 - Method of hygienically harmless stabilization of the polyolefine against degradation by ionizing radiation - Google Patents
Method of hygienically harmless stabilization of the polyolefine against degradation by ionizing radiation Download PDFInfo
- Publication number
- CS221405B1 CS221405B1 CS973881A CS973881A CS221405B1 CS 221405 B1 CS221405 B1 CS 221405B1 CS 973881 A CS973881 A CS 973881A CS 973881 A CS973881 A CS 973881A CS 221405 B1 CS221405 B1 CS 221405B1
- Authority
- CS
- Czechoslovakia
- Prior art keywords
- tocopherol
- ionizing radiation
- against degradation
- polyolefine
- stabilization
- Prior art date
Links
Landscapes
- Compositions Of Macromolecular Compounds (AREA)
Abstract
Způsob zdravotně nezávadné stabilizace polyolefinů proti degradaci ionizujícím- zářením, při kterém se jako stabilizátoru použije alfa-tokoferolu, beta-tokofe-rolu, gama- -tokoferolu, delta-tokoferolu nebo- j-ejich směsi.A method of health stabilization polyolefins against degradation by ionizing radiation, in which it is used as a stabilizer alpha-tocopherol, beta-tocopherol, gamma- tocopherol, delta-tocopherol or mixtures thereof.
Description
Způsob zdravotně nezávadné stabilizace polyolefinů proti degradaci ionizujícím- zářením, při kterém se jako stabilizátoru použije alfa-tokoferolu, beta-tokofe-rolu, gama-tokoferolu, delta-tokoferolu nebo- j-e jich směsi.Process for the stabilization of polyolefins against ionizing radiation degradation, wherein alpha-tocopherol, beta-tocopherol, gamma-tocopherol, delta-tocopherol or mixtures thereof are used as stabilizers.
Vynález se týká způsobu stabilizace polyolefinů, kterým se dosahuje zvýšená, odolnost proti degradaci ionizujícím zářením, přičemž polyolefiny stabilizované podle vynálezu jsou zdravotně nezávadné.The present invention relates to a process for stabilizing polyolefins which provides improved resistance to ionizing radiation degradation, wherein the polyolefins stabilized according to the invention are harmless to health.
Dosavadní způsob stabilizace polyolefinů proti degradaci ionizujícím zářením se provádí aplikací dterivátů fenolů, derivátů aromatických aminů- organických fosfitů, případně organických sirných sloučenin. Tyto látky jsou zdravotně závadné a ve styku s tkáněmi organismu vyvolávají nežádoucí zánětlivé procesy. U některých z těchto sloučenin byl zjištěn karcinogenní účinek (například u fenyl-beta-naftylaminuj.The present method of stabilizing polyolefins against degradation by ionizing radiation is carried out by applying phenol derivatives, aromatic amine derivatives - organic phosphites, or organic sulfur compounds. These substances are harmful to health and cause unwanted inflammatory processes in contact with the tissues of the organism. Some of these compounds have been found to be carcinogenic (e.g., phenyl-beta-naphthylamine).
Výše uvedené nedostatky jsou odstraněny stabilizací polyolfefinů podle vynálezu, jejíž podstatou je aplikace 0,01 až 5 % alfa-tokoferolu, beta-tokoferolu, gama-tokofero1lu, delta-tokoferolu nebo jejich směsí do polyolefihů.The above drawbacks are removed polyolfefinů stabilization according to the invention, the essence of the application is 0.01 to 5% of alpha-tocopherol, beta-tocopherol, gamma-tocopherol 1 IU, delta-tocopherol or mixtures thereof into polyolefihů.
Polyolefiny stabilizované tokoferolem mají stejnou-nebo vyšší odolnosti proti degradac ci ionizujícím zářením. Jsou z-drav-otně nezávadné. Nevyvolávají dráždění živé tkáně organismu -a příznivě působí na vhoj-ovací procesy. Jsou zvláště vhodné na zho-tov-ení výrobků určených pro Implantace d-o organismu, které je nutné sterilizovat gama zářením. Přítomnost tokoferolu v implantátech z polyolefinů podporuje hojení a zmírňuje zánětlivé procesy. Polyolefiny stabilizované tok-oferoiem mají také vyšší odolnost proti tepelné a termooxidační degradaci.The tocopherol-stabilized polyolefins have the same or higher resistance to degradation or ionizing radiation. They are health-friendly. They do not induce irritation of the living tissue of the organism and have a beneficial effect on the healing processes. They are particularly suitable for the manufacture of d-o implantation products which need to be sterilized by gamma irradiation. The presence of tocopherol in polyolefin implants promotes healing and alleviates inflammatory processes. Also, the polyolefins stabilized by the flux-oerium have higher resistance to thermal and thermo-oxidative degradation.
Způsob -stabilizace polyolefinů vyplývá z těchto příkladů.The method for stabilizing polyolefins follows from these examples.
Příklad liExample li
100 hmot. dílů polyethylenu se smísí s 0,1 hmot., díly, alfiat-tokofarolu. Po dokonalé homogenizaci' s-a: dále zpracovává technologiemi obvyklými· pro· zpracování plastů.100 wt. parts of polyethylene are mixed with 0.1 parts by weight of alpha-tocophorol. After perfect homogenization, it is further processed by conventional plastics processing technologies.
P ř í k 1 a d 2Example 1 a d 2
100 hmot. dílů polybutenu se smís-í- s 0,5 0,4 hmot. díly ste-arátů vápenatého· a s 1 hmot. dílem garna-tokoforolu. PO dokonalé homogenizaci se směs dále zpracovává technologiemi obvyklými pro zpracování plastů.100 wt. 0.5 parts by weight of polybutene are mixed with 0.5 wt. parts of calcium stearates and with 1 wt. by garna-tocophorol. After perfect homogenization, the mixture is further processed by technologies common for plastics processing.
Příklad 3·Example 3 ·
100 hmot. dílů -polybutenu se smísí s 0,5 díly alf-a-tokoferolu. Po dokonalé homogenizaci se směs dále zpracovává technologiemi obvyklými pro zpracování plastů.100 wt. 0.5 parts of polybutene are mixed with 0.5 parts of alpha-tocopherol. After perfect homogenization, the mixture is further processed by technologies common for plastics processing.
P ř í k l,a d. 4Ex. 4
100 hmot. dílů polymethylpentenu se smísí s 1,5 díly alfa-tokof-erolu. Po dokonalé -homogenizaci se směs dále zpracovává technologiemi obvyklými pro zpracování plastů.100 wt. parts of polymethylpentene are mixed with 1.5 parts of alpha-tocopherol. After perfect homogenization, the mixture is further processed by the techniques customary for plastics processing.
Při sterilizaci těchto směsí gama zářením dávkou 2,,5 Mrad nedošlo ke změně jeji-ch vlastností, kdežto u polyolefinů nestabilizovaných, například u polypropylenu, došlo k výraznému křehnu-tí, které znemožnilo další aplikace těchto- materiálů.The sterilization of these mixtures by gamma radiation at a dose of 2.5 Mrad did not alter its properties, while polyolefins unstabilized, for example polypropylene, exhibited significant embrittlement which prevented further application of these materials.
Claims (2)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CS973881A CS221405B1 (en) | 1981-12-23 | 1981-12-23 | Method of hygienically harmless stabilization of the polyolefine against degradation by ionizing radiation |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CS973881A CS221405B1 (en) | 1981-12-23 | 1981-12-23 | Method of hygienically harmless stabilization of the polyolefine against degradation by ionizing radiation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CS221405B1 true CS221405B1 (en) | 1983-04-29 |
Family
ID=5446310
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CS973881A CS221405B1 (en) | 1981-12-23 | 1981-12-23 | Method of hygienically harmless stabilization of the polyolefine against degradation by ionizing radiation |
Country Status (1)
| Country | Link |
|---|---|
| CS (1) | CS221405B1 (en) |
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8178594B2 (en) | 2007-04-10 | 2012-05-15 | Zimmer, Inc. | Antioxidant stabilized crosslinked ultra-high molecular weight polyethylene for medical device applications |
| US8470903B2 (en) | 2005-08-18 | 2013-06-25 | Zimmer Gmbh | Ultra high molecular weight polyethylene articles and methods of forming ultra high molecular weight polyethylene articles |
| US9708467B2 (en) | 2013-10-01 | 2017-07-18 | Zimmer, Inc. | Polymer compositions comprising one or more protected antioxidants |
| US9718241B2 (en) | 2008-01-30 | 2017-08-01 | Zimmer, Inc. | Method of manufacturing an acetabular component |
| US9822224B2 (en) | 2007-04-10 | 2017-11-21 | Zimmer, Inc. | Antioxidant stabilized crosslinked ultra high molecular weight polyethylene for medical device applications |
| US10184031B2 (en) | 2014-03-12 | 2019-01-22 | Zimmer, Inc. | Melt-stabilized ultra high molecular weight polyethylene and method of making the same |
| US10265891B2 (en) | 2014-12-03 | 2019-04-23 | Zimmer, Inc. | Antioxidant-infused ultra high molecular weight polyethylene |
-
1981
- 1981-12-23 CS CS973881A patent/CS221405B1/en unknown
Cited By (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8470903B2 (en) | 2005-08-18 | 2013-06-25 | Zimmer Gmbh | Ultra high molecular weight polyethylene articles and methods of forming ultra high molecular weight polyethylene articles |
| US8673202B2 (en) | 2005-08-18 | 2014-03-18 | Zimmer, Gmbh | Ultra high molecular weight polyethylene articles and methods of forming ultra high molecular weight polyethylene articles |
| US11001680B2 (en) | 2005-08-18 | 2021-05-11 | Zimmer Gmbh | Ultra high molecular weight polyethylene articles and methods of forming ultra high molecular weight polyethylene articles |
| US11015030B2 (en) | 2005-08-18 | 2021-05-25 | Zimmer Gmbh | Ultra high molecular weight polyethylene articles and methods of forming ultra high molecular weight polyethylene articles |
| US8178594B2 (en) | 2007-04-10 | 2012-05-15 | Zimmer, Inc. | Antioxidant stabilized crosslinked ultra-high molecular weight polyethylene for medical device applications |
| US9822224B2 (en) | 2007-04-10 | 2017-11-21 | Zimmer, Inc. | Antioxidant stabilized crosslinked ultra high molecular weight polyethylene for medical device applications |
| US9926432B2 (en) | 2007-04-10 | 2018-03-27 | Zimmer, Inc. | Antioxidant stabilized crosslinked ultra-high molecular weight polyethylene for medical device applications |
| US10556998B2 (en) | 2007-04-10 | 2020-02-11 | Zimmer, Inc. | Antioxidant stabilized crosslinked ultra high molecular weight polyethylene for medical device applications |
| US9718241B2 (en) | 2008-01-30 | 2017-08-01 | Zimmer, Inc. | Method of manufacturing an acetabular component |
| US9708467B2 (en) | 2013-10-01 | 2017-07-18 | Zimmer, Inc. | Polymer compositions comprising one or more protected antioxidants |
| US10184031B2 (en) | 2014-03-12 | 2019-01-22 | Zimmer, Inc. | Melt-stabilized ultra high molecular weight polyethylene and method of making the same |
| US10265891B2 (en) | 2014-12-03 | 2019-04-23 | Zimmer, Inc. | Antioxidant-infused ultra high molecular weight polyethylene |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US9971267B2 (en) | Synergistic effects on blending multiple additives in UHMWPE | |
| Hoburg et al. | Fractionation of high-dose electron beam irradiation of BPTB grafts provides significantly improved viscoelastic and structural properties compared to standard gamma irradiation | |
| ES2095889T3 (en) | POLYMERIC COMPOSITION OF A LUBRICANT CHARACTER STABLE TO RADIATION AND ARTICLES MADE FROM THEM. | |
| EP0401772A3 (en) | High clarity radiation stable polymeric composition and articles therefrom | |
| CS221405B1 (en) | Method of hygienically harmless stabilization of the polyolefine against degradation by ionizing radiation | |
| CS221403B1 (en) | Method of hygienic faultless stabilization of the polyolefine against thermooxidation and photooxidation degradation | |
| BR0010257A (en) | Compound, process for the preparation of a compound, pharmaceutical formulation, use of a compound, method for treatment or prophylaxis of conditions associated with the inhibition of carboxypeptidase u, kits of parts, and method of treating a patient suffering from or susceptible to a condition where inhibition of carboxypeptidase and a different antithrombotic mechanism are needed or desired | |
| ES2106042T3 (en) | CALCIUM INCORPORATION INHIBITORS. | |
| Allaveisi et al. | Radioprotective effect of N-acetyl-L-cysteine free radical scavenger on compressive mechanical properties of the gamma sterilized cortical bone of bovine femur | |
| BR9406059A (en) | Pharmaceutical composition and method for treating helminth infection in an animal | |
| ES2196049T3 (en) | USE OF 2- (2-ALQUILFENILAMINO) OXAZOLINAS AND -TIAZOLINAS FOR THE MANUFACTURE OF A MEDICINAL WITH ALFA 2 ADRENERGIC EFFECT. | |
| YU51588A (en) | Process for obtaining healing grease for burns and other injuries | |
| Reich et al. | Sporicidal efficacy of genipin: a potential theoretical alternative for biomaterial and tissue graft sterilization | |
| JPS6094438A (en) | Stabilization of semi-crystalline polymer against high energy radiation | |
| US4533351A (en) | Foam rubber insoles containing Ottacide-P | |
| ES2074037T1 (en) | DIMERO OF THE LISOZIMA AND COMPOSITIONS THAT CONTAIN IT. | |
| MX9704485A (en) | Embrittlement-resistant polyolefin composition and flexible articles therefrom. | |
| Chanway et al. | Effect of ethylene diurea (EDU) on ozone tolerance and superoxide dismutase activity in bush bean | |
| BR0311384A (en) | Compound, process for preparing same, pharmaceutical formulation, use of a compound, and method for treating or prophylaxis of conditions wherein inhibition of carboxypeptidase u is beneficial | |
| CS221404B1 (en) | Method of stabilization of polyolefine for attaining the increased resistance against biological degradation of the organism | |
| FI101849B1 (en) | Antimicrobial compositions and their use for preserving ophthalmic drugs and treating contact lenses | |
| GB2093463A (en) | Radiation-resistant Olefin Polymer | |
| DE3751974D1 (en) | Serotonin antagonists used to treat wounds | |
| FI914408A (en) | CALCIUMUPPTAGANDE INHIBITORER. | |
| HUT62474A (en) | Process for producing veterinary composition with antiparasitic effect |