[go: up one dir, main page]
More Web Proxy on the site http://driver.im/

CR11267A - Preparacion solida que contiene alogliptina y clorhidrato de metformina - Google Patents

Preparacion solida que contiene alogliptina y clorhidrato de metformina

Info

Publication number
CR11267A
CR11267A CR11267A CR11267A CR11267A CR 11267 A CR11267 A CR 11267A CR 11267 A CR11267 A CR 11267A CR 11267 A CR11267 A CR 11267A CR 11267 A CR11267 A CR 11267A
Authority
CR
Costa Rica
Prior art keywords
alogliptine
chlorhydrate
metformin
preparation containing
solid preparation
Prior art date
Application number
CR11267A
Other languages
English (en)
Spanish (es)
Inventor
Kazumichi Yamamoto
Hiroyoshi Koyama
Original Assignee
Takeda Pharmaceutical
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39930391&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CR11267(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Takeda Pharmaceutical filed Critical Takeda Pharmaceutical
Publication of CR11267A publication Critical patent/CR11267A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/513—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim having oxo groups directly attached to the heterocyclic ring, e.g. cytosine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/2853—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers, poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
    • A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Vascular Medicine (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Child & Adolescent Psychology (AREA)
  • Urology & Nephrology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CR11267A 2007-07-19 2010-02-12 Preparacion solida que contiene alogliptina y clorhidrato de metformina CR11267A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2007188574 2007-07-19

Publications (1)

Publication Number Publication Date
CR11267A true CR11267A (es) 2010-05-03

Family

ID=39930391

Family Applications (1)

Application Number Title Priority Date Filing Date
CR11267A CR11267A (es) 2007-07-19 2010-02-12 Preparacion solida que contiene alogliptina y clorhidrato de metformina

Country Status (27)

Country Link
US (1) US8900638B2 (fr)
EP (1) EP2185138B1 (fr)
JP (2) JP5479318B2 (fr)
KR (1) KR101536786B1 (fr)
CN (1) CN101801351B (fr)
AR (1) AR067557A1 (fr)
AU (1) AU2008276842C9 (fr)
BR (1) BRPI0814299B8 (fr)
CA (1) CA2694620C (fr)
CO (1) CO6160301A2 (fr)
CR (1) CR11267A (fr)
DO (1) DOP2010000028A (fr)
EA (1) EA020870B1 (fr)
EC (1) ECSP109979A (fr)
ES (1) ES2603879T3 (fr)
GE (1) GEP20125672B (fr)
IL (1) IL203171A (fr)
JO (1) JO3272B1 (fr)
MA (1) MA31592B1 (fr)
MY (1) MY159203A (fr)
NZ (1) NZ583346A (fr)
PE (2) PE20140923A1 (fr)
TN (1) TN2010000019A1 (fr)
TW (1) TWI421102B (fr)
UA (1) UA98799C2 (fr)
WO (1) WO2009011451A1 (fr)
ZA (1) ZA201000831B (fr)

Families Citing this family (61)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7407955B2 (en) 2002-08-21 2008-08-05 Boehringer Ingelheim Pharma Gmbh & Co., Kg 8-[3-amino-piperidin-1-yl]-xanthines, the preparation thereof and their use as pharmaceutical compositions
US7501426B2 (en) 2004-02-18 2009-03-10 Boehringer Ingelheim International Gmbh 8-[3-amino-piperidin-1-yl]-xanthines, their preparation and their use as pharmaceutical compositions
DE102004054054A1 (de) 2004-11-05 2006-05-11 Boehringer Ingelheim Pharma Gmbh & Co. Kg Verfahren zur Herstellung chiraler 8-(3-Amino-piperidin-1-yl)-xanthine
DE102005035891A1 (de) 2005-07-30 2007-02-08 Boehringer Ingelheim Pharma Gmbh & Co. Kg 8-(3-Amino-piperidin-1-yl)-xanthine, deren Herstellung und deren Verwendung als Arzneimittel
PE20110235A1 (es) 2006-05-04 2011-04-14 Boehringer Ingelheim Int Combinaciones farmaceuticas que comprenden linagliptina y metmorfina
NO347644B1 (no) 2006-05-04 2024-02-12 Boehringer Ingelheim Int Polymorfer
EP1852108A1 (fr) 2006-05-04 2007-11-07 Boehringer Ingelheim Pharma GmbH & Co.KG Compositions d'inhibiteurs de la DPP IV
PE20140923A1 (es) * 2007-07-19 2014-08-11 Takeda Pharmaceutical Preparacion solida que comprende alogliptina y clorhidrato de metformina
CN102006861B (zh) 2008-02-13 2012-11-21 大日本住友制药株式会社 口腔崩解片
PE20091730A1 (es) 2008-04-03 2009-12-10 Boehringer Ingelheim Int Formulaciones que comprenden un inhibidor de dpp4
UY32030A (es) 2008-08-06 2010-03-26 Boehringer Ingelheim Int "tratamiento para diabetes en pacientes inapropiados para terapia con metformina"
KR20200118243A (ko) 2008-08-06 2020-10-14 베링거 인겔하임 인터내셔날 게엠베하 메트포르민 요법이 부적합한 환자에서의 당뇨병 치료
NZ604091A (en) 2008-08-15 2014-08-29 Boehringer Ingelheim Int Purin derivatives for use in the treatment of fab-related diseases
KR20110067096A (ko) 2008-09-10 2011-06-21 베링거 인겔하임 인터내셔날 게엠베하 당뇨병 및 관련 상태를 치료하기 위한 병용 요법
AR073380A1 (es) * 2008-09-25 2010-11-03 Takeda Pharmaceutical Composicion farmaceutica solida. comprimido multicapa
US20200155558A1 (en) 2018-11-20 2020-05-21 Boehringer Ingelheim International Gmbh Treatment for diabetes in patients with insufficient glycemic control despite therapy with an oral antidiabetic drug
NZ592924A (en) 2008-12-23 2014-05-30 Boehringer Ingelheim Int Salt forms of a xanthine derivative
AR074990A1 (es) 2009-01-07 2011-03-02 Boehringer Ingelheim Int Tratamiento de diabetes en pacientes con un control glucemico inadecuado a pesar de la terapia con metformina
TWI466672B (zh) 2009-01-29 2015-01-01 Boehringer Ingelheim Int 小兒科病人糖尿病之治療
CA2752437C (fr) 2009-02-13 2017-07-11 Boehringer Ingelheim International Gmbh Medicaments antidiabetiques
JP2012521411A (ja) 2009-03-26 2012-09-13 マピ ファーマ リミテッド アログリプチンの調製プロセス
TW201043640A (en) * 2009-05-13 2010-12-16 Wyeth Llc Method to stabilize a dietary supplement to facilitate joint health in humans
RU2558798C2 (ru) 2009-11-13 2015-08-10 Астразенека Аб Составы таблетки с немедленным высвобождением
LT2498758T (lt) 2009-11-13 2018-11-26 Astrazeneca Ab Dvisluoksnės tabletės formuluotės
EA034869B1 (ru) 2009-11-27 2020-03-31 Бёрингер Ингельхайм Интернациональ Гмбх Лечение генотипированных пациентов с диабетом ингибиторами дпп-4, такими как линаглиптин
JP2013522279A (ja) 2010-03-18 2013-06-13 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 糖尿病及び関連状態の治療で用いるｇｐｒ１１９作動薬とｄｄｐ−ｉｖ阻害薬リナグリプチンの組合せ
WO2011138421A1 (fr) 2010-05-05 2011-11-10 Boehringer Ingelheim International Gmbh Combinaison thérapeutique
US20130059872A1 (en) * 2010-05-12 2013-03-07 Mapi Pharma Limited Polymorphs of alogliptin benzoate
KR20130093012A (ko) 2010-06-24 2013-08-21 베링거 인겔하임 인터내셔날 게엠베하 당뇨병 요법
JP2012051832A (ja) * 2010-08-31 2012-03-15 Fancl Corp 顆粒組成物及びそれを含有する食品又は医薬品
US9034883B2 (en) 2010-11-15 2015-05-19 Boehringer Ingelheim International Gmbh Vasoprotective and cardioprotective antidiabetic therapy
EP3517539B1 (fr) 2011-07-15 2022-12-14 Boehringer Ingelheim International GmbH Dérivé de quinazoline dimère substitué, sa préparation et son utilisation dans des compositions pharmaceutiques pour le traitement du diabète de type i et ii
WO2013077825A1 (fr) * 2011-11-23 2013-05-30 Mahmut Bilgic Procédé de fabrication d'une préparation comprenant de la metformine
US9555001B2 (en) 2012-03-07 2017-01-31 Boehringer Ingelheim International Gmbh Pharmaceutical composition and uses thereof
JP6224084B2 (ja) 2012-05-14 2017-11-01 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 糸球体上皮細胞関連障害及び／又はネフローゼ症候群の治療に用いるｄｐｐ−４阻害薬としてのキサンチン誘導体
WO2013174767A1 (fr) 2012-05-24 2013-11-28 Boehringer Ingelheim International Gmbh Dérivé de xanthine en tant qu'inhibiteur de la dpp-4 à utiliser dans la modification de l'apport alimentaire et dans la régulation des préférences alimentaires
WO2014036528A2 (fr) 2012-08-31 2014-03-06 Ixchel Pharma, Llc Agents utiles pour le traitement de l'obésité, du diabète et de troubles associés
CN103877054B (zh) * 2012-12-21 2016-05-25 北大方正集团有限公司 一种苯甲酸阿格列汀片剂及其制备方法
EP2769712A1 (fr) * 2013-02-21 2014-08-27 Siegfried International AG Formulation pharmaceutique comportant des agglomérats d'inhibiteur DPP-IV et des particules d'inhibiteur DPP-IV
CN103353491B (zh) * 2013-06-29 2018-11-16 北京万全德众医药生物技术有限公司 一种用液相色谱法分离测定苯甲酸阿格列汀原料及其制剂的方法
JP5922310B2 (ja) * 2013-07-25 2016-05-24 株式会社三和化学研究所 医薬製剤
CN104749269B (zh) * 2013-12-31 2018-12-28 中美华世通生物医药科技（武汉）有限公司 一种利用hplc测定阿格列汀原料药及制剂中对映异构体杂质的方法
JP6615109B2 (ja) 2014-02-28 2019-12-04 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング Ｄｐｐ−４阻害薬の医学的使用
CN105527348B (zh) * 2014-09-28 2018-07-24 中美华世通生物医药科技（武汉）有限公司 分离分析苯甲酸阿格列汀制剂及其有关物质的方法
CN104569172A (zh) * 2014-11-05 2015-04-29 广东东阳光药业有限公司 一种用液相色谱检测苯甲酸阿格列汀片溶出度的方法
CN105675733B (zh) * 2014-11-17 2020-01-31 重庆医药工业研究院有限责任公司 一种用液相色谱法分离测定琥珀酸曲格列汀及其光学异构体的方法
CA2967210C (fr) * 2014-12-03 2023-06-13 Caffitaly System S.P.A. Corps de contenant pour realiser une capsule pour realiser des boissons, et procede pour realiser des capsules avec des quantites differentes de substance alimentaire en poudre a l'aide d'un type unique de corps de contenant
EP3310357A1 (fr) 2015-06-17 2018-04-25 H e x a l Aktiengesellschaft Formulation d'alogliptine
WO2017029609A1 (fr) * 2015-08-20 2017-02-23 Torrent Pharmaceuticals Limited Composition pharmaceutique d'alogliptine et de metformine
WO2017033115A1 (fr) * 2015-08-21 2017-03-02 Alembic Pharmaceuticals Limited Composition pharmaceutique stable d'une combinaison à dose fixée d'alogliptine et de metformine
BR112018008651A2 (pt) * 2015-10-30 2018-10-30 Cancer Prevention Pharmaceuticals Inc formulação de combinação de dose fixa de eflornitina e sulindaco
EP4233840A3 (fr) 2016-06-10 2023-10-18 Boehringer Ingelheim International GmbH Combinaisons de linagliptine et de metformine
CN106008277A (zh) * 2016-06-12 2016-10-12 聊城大学 一种新型二甲双胍盐酸盐及其制备方法
CN106421794A (zh) * 2016-09-27 2017-02-22 黑龙江珍宝岛药业股份有限公司 一种用于治疗ⅱ型糖尿病的药物组合物及其制备方法
CN108318610A (zh) * 2017-12-29 2018-07-24 合肥拓锐生物科技有限公司 一种苯甲酸阿格列汀原料及其制剂中有关物质的分析方法
EP3784672A4 (fr) 2018-04-27 2022-03-30 Sanovel Ilac Sanayi Ve Ticaret Anonim Sirketi Formulations de comprimés comprenant de la metformine et de la sitagliptine
CN108743611A (zh) * 2018-06-20 2018-11-06 常州制药厂有限公司 一种复方利血平片的制备方法
WO2020098904A1 (fr) 2018-11-12 2020-05-22 Pharmaceutical Oriented Services Ltd Forme posologique contenant de la metformine et un inhibiteur de la dipeptidyl peptidase iv
TR201907905A1 (tr) * 2019-05-24 2020-12-21 Sanovel Ilac Sanayi Ve Ticaret Anonim Sirketi Alogli̇pti̇n ve metformi̇n i̇çeren bi̇r kombi̇nasyon
CN111537622B (zh) * 2019-11-29 2021-11-26 杭州华东医药集团新药研究院有限公司 一种度格列汀及其盐的杂质的检测方法
TW202329921A (zh) 2021-10-08 2023-08-01 南韓商賽特瑞恩股份有限公司 具有經改善穩定性的用於治療糖尿病的醫藥組合物

Family Cites Families (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3174901A (en) * 1963-01-31 1965-03-23 Jan Marcel Didier Aron Samuel Process for the oral treatment of diabetes
JPS49110814A (fr) * 1973-03-02 1974-10-22
WO1997010224A1 (fr) 1995-09-13 1997-03-20 Takeda Chemical Industries, Ltd. Composes de benzoxazepine, leur production et leur utilisation en tant qu'agent d'abaissement des niveaux de lipides
EP2433623A1 (fr) 1998-02-02 2012-03-28 Trustees Of Tufts College Utilisation d'inhibiteurs de la dipeptidylpeptidase pour réguler le métabolisme du glucose
EP0974356B1 (fr) 1998-07-15 2003-09-24 Merck Sante Comprimés contenant une combinaison de glibenclamide et de metformine
AR035016A1 (es) 1999-08-25 2004-04-14 Takeda Chemical Industries Ltd Composicion de azol promotor de produccion/secrecion de neurotrofina, compuesto prodroga del mismo, composicion farmaceutica que lo comprende y uso del mismo para preparar esta ultima.
US6559188B1 (en) * 1999-09-17 2003-05-06 Novartis Ag Method of treating metabolic disorders especially diabetes, or a disease or condition associated with diabetes
RU2280447C2 (ru) 1999-09-17 2006-07-27 Новартис Аг Способ лечения нарушений метаболизма, прежде всего диабета или заболеваний или состояний, связанных с диабетом
IL149139A0 (en) 1999-11-03 2002-11-10 Bristol Myers Squibb Co Pharmaceutical compositions containing metformin and glyburide
PT1285651E (pt) 2000-04-28 2010-10-21 Takeda Pharmaceutical Antagonistas da hormona concentradora da melanina
US6403121B1 (en) * 2000-05-01 2002-06-11 Aeropharm Technology Incorporated Core formulation
US6780432B1 (en) 2000-05-01 2004-08-24 Aeropharm Technology, Inc. Core formulation
AU2001256733A1 (en) * 2000-05-16 2001-11-26 Takeda Chemical Industries Ltd. Melanin-concentrating hormone antagonist
GB0014969D0 (en) 2000-06-19 2000-08-09 Smithkline Beecham Plc Novel method of treatment
EP1363604A2 (fr) * 2001-02-14 2003-11-26 Glaxo Wellcome S.A. Composition pharmaceutique
US6524618B1 (en) * 2001-06-12 2003-02-25 Vijai Kumar Directly compressible extended-release matrix formulation for metformin hydrochloride
CA2452558C (fr) 2001-07-17 2009-12-22 N-Gene Research Laboratories Inc. Combinaison pharmaceutique synergique pour prevenir ou traiter le diabete
KR20040044992A (ko) 2001-09-28 2004-05-31 썬 파마슈티컬 인더스트리스 리미티드 당뇨병 치료용 투여형태
US20030187074A1 (en) * 2002-03-04 2003-10-02 Javed Hussain Oral compositions for treatment of diabetes
US20030224046A1 (en) * 2002-06-03 2003-12-04 Vinay Rao Unit-dose combination composition for the simultaneous delivery of a short-acting and a long-acting oral hypoglycemic agent
US20040125143A1 (en) 2002-07-22 2004-07-01 Kenneth Deaton Display system and method for displaying a multi-dimensional file visualizer and chooser
EP1543023B1 (fr) 2002-09-18 2010-03-17 Prosidion Limited Site secondaire de liaison de dipeptidyl peptidase (dp iv)
EP1557165A4 (fr) * 2002-09-26 2008-12-03 Eisai R&D Man Co Ltd Medicament combine
UA80991C2 (en) 2002-10-07 2007-11-26 Solid preparation containing an insulin resistance improving drug and an active ingredient useful as a remedy for diabetes
WO2004110375A2 (fr) 2003-06-06 2004-12-23 Merck & Co., Inc. Polytherapie permettant de traiter le diabete
AU2004265341A1 (en) 2003-08-13 2005-02-24 Takeda Pharmaceutical Company Limited 4-pyrimidone derivatives and their use as peptidyl peptidase inhibitors
TWI350751B (en) * 2003-12-19 2011-10-21 Omega Bio Pharma Ip3 Ltd Pharmaceutical compositions for treating diabetes
CN102127053A (zh) * 2004-03-15 2011-07-20 武田药品工业株式会社 二肽基肽酶抑制剂
KR100760430B1 (ko) * 2004-12-31 2007-10-04 한미약품 주식회사 당뇨병 치료제의 경구 투여용 서방성 복합 제제 및 이의제조 방법
MXPA05009633A (es) * 2005-09-08 2007-03-07 Silanes Sa De Cv Lab Composicion farmaceutica estable de glimepirida de liberacion inmediata y metformina de liberacion prolongada.
PT1931350E (pt) * 2005-09-14 2014-02-12 Takeda Pharmaceutical Administração de inibidores de dipeptidil peptidase
TW200745079A (en) * 2005-09-16 2007-12-16 Takeda Pharmaceuticals Co Polymorphs of benzoate salt of 2-[[6-[(3R)-3-amino-1-piperidinyl]-3,4-dihydro-3-methyl-2,4-dioxo-1(2H)-pyrimidinyl]methyl]-benzonitrile and methods of use therefor
EP1962827A4 (fr) 2005-12-16 2011-02-16 Merck Sharp & Dohme Compositions pharmaceutiques contenant des combinaisons d'inhibiteurs de la dipeptidylpeptidase 4 avec de la métformine
GB0526291D0 (en) 2005-12-23 2006-02-01 Prosidion Ltd Therapeutic method
CA2635777A1 (fr) 2005-12-28 2007-07-05 Takeda Pharmaceutical Company Limited Traitement combine du diabete
RU2333760C2 (ru) 2006-05-16 2008-09-20 Открытое акционерное общество "Химико-фармацевтический комбинат "АКРИХИН" (ОАО "АКРИХИН") Твердая дозированная лекарственная форма для лечения сахарного диабета
TW200826936A (en) * 2006-12-01 2008-07-01 Merck Frosst Canada Ltd Azacycloalkane derivatives as inhibitors of stearoyl-coenzyme a delta-9 desaturase
NZ579008A (en) * 2007-02-01 2012-02-24 Takeda Pharmaceutical Solid preparation comprising alogliptin and pioglitazone
CA2677193C (fr) 2007-02-01 2015-06-30 Takeda Pharmaceutical Company Limited Preparation de comprime ne provoquant pas de probleme de pastillage
PE20140923A1 (es) * 2007-07-19 2014-08-11 Takeda Pharmaceutical Preparacion solida que comprende alogliptina y clorhidrato de metformina
RU2380097C1 (ru) 2009-01-20 2010-01-27 Общество с ограниченной ответственностью "ИТЭРА" Твердая дозированная лекарственная форма для лечения сахарного диабета

Also Published As

Publication number Publication date
MY159203A (en) 2016-12-30
KR20100036367A (ko) 2010-04-07
ES2603879T3 (es) 2017-03-01
TW200914066A (en) 2009-04-01
CA2694620C (fr) 2016-05-31
CN101801351B (zh) 2012-12-12
PE20090882A1 (es) 2009-08-03
CO6160301A2 (es) 2010-05-20
CA2694620A1 (fr) 2009-01-22
TN2010000019A1 (en) 2011-09-26
CN101801351A (zh) 2010-08-11
EP2185138B1 (fr) 2016-09-07
BRPI0814299B8 (pt) 2021-05-25
EA020870B1 (ru) 2015-02-27
JP5479318B2 (ja) 2014-04-23
ZA201000831B (en) 2011-04-28
AU2008276842A1 (en) 2009-01-22
ECSP109979A (es) 2010-03-31
JO3272B1 (ar) 2018-09-16
GEP20125672B (en) 2012-10-25
DOP2010000028A (es) 2010-02-15
AU2008276842C9 (en) 2014-08-21
US20100136127A1 (en) 2010-06-03
EP2185138A1 (fr) 2010-05-19
AU2008276842B2 (en) 2013-07-04
PE20140923A1 (es) 2014-08-11
AU2008276842C1 (en) 2013-11-28
JP2010533643A (ja) 2010-10-28
US8900638B2 (en) 2014-12-02
IL203171A (en) 2016-11-30
WO2009011451A1 (fr) 2009-01-22
MA31592B1 (fr) 2010-08-02
KR101536786B1 (ko) 2015-07-14
US20110014299A2 (en) 2011-01-20
BRPI0814299B1 (pt) 2018-12-18
AR067557A1 (es) 2009-10-14
EA201070164A1 (ru) 2010-08-30
TWI421102B (zh) 2014-01-01
NZ583346A (en) 2012-02-24
BRPI0814299A2 (pt) 2015-02-03
UA98799C2 (ru) 2012-06-25
JP2014058547A (ja) 2014-04-03

Similar Documents

Publication Publication Date Title
CR11267A (es) Preparacion solida que contiene alogliptina y clorhidrato de metformina
UY31274A1 (es) Composiciones de recubrimiento electrodepositable que contiene una guanidina ciclica
HN2008000188A (es) 7- aza- indazoles sustituidos, composiciones que los contienen, procedimiento de fabricacion y su utilizacion
DE602008000754D1 (de) Tropanverbindungen
GT200800209A (es) Compuestos organicos
AR059194A1 (es) Formas de dosificacion resistentes a la manipulacion
CR9280S (es) Botella
CR10662A (es) Compuestos de metilpiridopirimidinona
CR10328A (es) Compuestos organicos
GT200700002S (es) Cubierta de recipiente
HN2006037713A (es) Compuestos utiles en terapia
CR11123A (es) Compuestos triciclicos que contienen nitrogeno como agentes antibacteriales
PA8671301A1 (es) Pirrolopiridinas sustituidas, composiciones que las contienen, proceso de fabricación y utilización
SV2011003853A (es) Compuestos organicos
GT200800276A (es) Composiciones farmaceuticas estabilizadas que comprenden fesoterodina
UY31563A1 (es) Azolilmetiloxiranos, su uso y agentes que los contienen
UY31562A1 (es) Azolilmetiloxiranos, su uso y agentes que los contienen
UY31560A1 (es) Azolilmetiloxiranos, su uso y agentes que los contienen
SV2011003800A (es) Derivados de piridino-piridinonas, su preparacion y su aplicacion en terapeutica
CR9344S (es) Regadera
HN2007016864A (es) Contenedor
UY31688A1 (es) Plaguicidas
SV2009003253A (es) Pirazoles sustituidos, composiciones que los contienen, procedimiento de fabricacion y utilizacion
ECSP099561A (es) Formulación de nevirapina de liberación prolongada
PA8846401A1 (es) Sinergismo antibiótico