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CR10712A - Derivados de quinazolinona 5-sustituidos como agentes antitumorales - Google Patents

Derivados de quinazolinona 5-sustituidos como agentes antitumorales

Info

Publication number
CR10712A
CR10712A CR10712A CR10712A CR10712A CR 10712 A CR10712 A CR 10712A CR 10712 A CR10712 A CR 10712A CR 10712 A CR10712 A CR 10712A CR 10712 A CR10712 A CR 10712A
Authority
CR
Costa Rica
Prior art keywords
substituted
quinazolinona
derivatives
antitumor agents
compounds
Prior art date
Application number
CR10712A
Other languages
English (en)
Inventor
George W Muller
Hong Wah Man
Original Assignee
Celgene Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Celgene Corp filed Critical Celgene Corp
Publication of CR10712A publication Critical patent/CR10712A/es

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    • C07—ORGANIC CHEMISTRY
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    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
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Abstract

Se proveen compuestos de quinazolinona 5-sustituidos y sales, solvatos, clatratos, estereoisomeros y profarmacos farmaceuticamente aceptables de los mismos. Se describen metodos de uso y composiciones farmaceuticas de estos compuestos.
CR10712A 2006-09-26 2009-04-14 Derivados de quinazolinona 5-sustituidos como agentes antitumorales CR10712A (es)

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