[go: up one dir, main page]
More Web Proxy on the site http://driver.im/

CO7210309A2 - Aerosol inhalation device - Google Patents

Aerosol inhalation device

Info

Publication number
CO7210309A2
CO7210309A2 CO15043974A CO15043974A CO7210309A2 CO 7210309 A2 CO7210309 A2 CO 7210309A2 CO 15043974 A CO15043974 A CO 15043974A CO 15043974 A CO15043974 A CO 15043974A CO 7210309 A2 CO7210309 A2 CO 7210309A2
Authority
CO
Colombia
Prior art keywords
hole
actuator
duct
opening
tubular element
Prior art date
Application number
CO15043974A
Other languages
Spanish (es)
Inventor
Gaetano Brambilla
Robert Johnson
David Andrew Lewis
Original Assignee
Chiesi Farma Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chiesi Farma Spa filed Critical Chiesi Farma Spa
Priority to CO15043974A priority Critical patent/CO7210309A2/en
Publication of CO7210309A2 publication Critical patent/CO7210309A2/en

Links

Landscapes

  • Containers And Packaging Bodies Having A Special Means To Remove Contents (AREA)

Abstract

Un actuador de un dispositivo de inhalación de aerosol que comprende un alojamiento que está adaptado para recibir un recipiente de aerosol que contiene una formulación de medicamento presurizada, una porción de conducto a través de la cual inhala el usuario, un conjunto de boquilla y un orificio que se caracteriza por la presencia de un elemento tubular que se extiende en la porción de conducto desde la abertura del orificio en un eje longitudinal que está alineado con un eje longitudinal de la porción de conducto. En particular, dicho elemento tubular está posicionado para encerrar la abertura del orificio dentro de una cavidad. El elemento tubular está configurado de modo tal que una de sus aberturas terminales puede tener un ajuste apretado con la superficie externa del conjunto de boquilla alrededor de la abertura del orificio para poder estar en una trayectoria de flujo continuo con el orificio. Entre las ventajas del actuador de la invención está la reducción significativa de la fracción gruesa no respirable del medicamento emitido de aerosol por medio del impacto inercial y la retención en el actuador más que en la orofaringe con los consiguientes menores efectos laterales asociados y candidiasis oral en el paciente. Además, la presencia del elemento tubular tiene un impacto mínimo y despreciable en la dosis de partículas finas y en la distribución del tamaño de partícula (PSD) de las partículas administradas que tienen un diámetro aerodinámico menor que 9 um.An actuator of an aerosol inhalation device comprising a housing that is in use; adapted to receive an aerosol container containing a pressurized drug formulation, a portion of the duct through which the user inhales, a mouthpiece assembly and a hole characterized by the presence of an element tubular that extends into the portion of the duct from the opening of the hole in a longitudinal axis that is located; aligned with a longitudinal axis of the duct portion. In particular, said tubular element is positioned to enclose the opening of the hole inside a cavity. The tubular element is configured such that one of its terminal openings can have a tight fit with the outer surface of the nozzle assembly around the opening of the hole so that it can be in a continuous flow path with the hole. Among the advantages of the actuator of the invention are: the significant reduction of the non-respirable thick fraction of the aerosol-emitted medication through inertial impact and retention in the actuator more than in the oropharynx with the consequent lower associated side effects and oral candidiasis in the patient. In addition, the presence of the tubular element has a minimal and negligible impact on the dose of fine particles and on the distribution of the particle size (PSD) of the particles administered which have an aerodynamic meter smaller than 9 um.

CO15043974A 2015-02-26 2015-02-26 Aerosol inhalation device CO7210309A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CO15043974A CO7210309A2 (en) 2015-02-26 2015-02-26 Aerosol inhalation device

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CO15043974A CO7210309A2 (en) 2015-02-26 2015-02-26 Aerosol inhalation device

Publications (1)

Publication Number Publication Date
CO7210309A2 true CO7210309A2 (en) 2015-03-09

Family

ID=53189520

Family Applications (1)

Application Number Title Priority Date Filing Date
CO15043974A CO7210309A2 (en) 2015-02-26 2015-02-26 Aerosol inhalation device

Country Status (1)

Country Link
CO (1) CO7210309A2 (en)

Similar Documents

Publication Publication Date Title
AR092274A1 (en) ACTUATOR OF AN AEROSOL AND INHALER INHALATION DEVICE
JP2014526447A5 (en)
JP2014509313A5 (en)
UY28908A1 (en) INHALING DRUG DEVICE
JP2013544781A5 (en)
BR112015001876A2 (en) space filler
MX2016015179A (en) A liquid formulation comprising nicotine for aerosol administration.
CO5060522A1 (en) ADMINISTRATION OF AN ACTIVE AGENT IN AEROSOL
AR102838A1 (en) DRY POWDER INHALER
CR20130262A (en) INHALER
AR092261A1 (en) NICOTINE COMPOSITIONS
BR112017021784A2 (en) inhalation device, inhalation device assembly and nozzle plate therefor
PE20150604A1 (en) SYSTEM FOR THE ADMINISTRATION OF A PULMONARY SURFACTANT BY ATOMIZATION
JP2013534227A5 (en)
BR112018010063A2 (en) porous structures for extended release drug delivery devices
JP2015505541A5 (en)
AR093382A1 (en) DRUG ADMINISTRATION DEVICE FOR THE TREATMENT OF PATIENTS WITH RESPIRATORY DISEASES
AR095547A1 (en) NEBULIZER FOR BABIES AND PATIENTS WITH RESPIRATORY COMMITMENT
AR067768A1 (en) INHALER
MA40374A1 (en) Unit dose powder inhaler and its method of manufacture
AR099364A1 (en) MEDICATION INHALER
EA201190182A1 (en) COUNTER INHALER DRY POWDER
AR098146A1 (en) IMPROVED METHOD AND SYSTEM TO ADMINISTER BY PULMONARY TENSIOACTIVE AGENT BY ATOMIZATION
CO2021007141A2 (en) Inhalable compositions for use in the treatment of lung diseases
CO2020006951A2 (en) Fulvestrant formulations and methods of their use