CO6190539A2 - Composiciones de carbamato fenilalquilo - Google Patents
Composiciones de carbamato fenilalquiloInfo
- Publication number
- CO6190539A2 CO6190539A2 CO09037411A CO09037411A CO6190539A2 CO 6190539 A2 CO6190539 A2 CO 6190539A2 CO 09037411 A CO09037411 A CO 09037411A CO 09037411 A CO09037411 A CO 09037411A CO 6190539 A2 CO6190539 A2 CO 6190539A2
- Authority
- CO
- Colombia
- Prior art keywords
- approximately
- range
- compound
- composition
- phenyl
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/325—Carbamic acids; Thiocarbamic acids; Anhydrides or salts thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2009—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A61P25/10—Antiepileptics; Anticonvulsants for petit-mal
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A61P25/12—Antiepileptics; Anticonvulsants for grand-mal
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Pain & Pain Management (AREA)
- Epidemiology (AREA)
- Inorganic Chemistry (AREA)
- Psychiatry (AREA)
- Physical Education & Sports Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Vascular Medicine (AREA)
- Hospice & Palliative Care (AREA)
- Urology & Nephrology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
1.- Una composición de un compuesto de carbamato fenilalquilo que comprende una mezcla del compuesto con una cantidad efectiva de uno o más excipientes en donde por lo menos un excipiente es dihidrato de fosfato de calcio dibásico, por lo cual el dihidrato de fosfato de calcio dibásico reduce la degradación del compuesto carbamato fenilalquilo en la composición. 2.- La composición de la reivindicación 1, en donde el compuesto es un compuesto de fórmula (I):o su forma de éster en donde fenilo se sustituye en X con uno a cinco átomos de halógeno independientemente seleccionados del grupo que consiste de flúor, cloro, bromo y yodo; y, R1 y R2 se seleccionan independientemente del grupo que consiste de hidrógeno y alquilo C1-4; en donde alquilo C1-4 se sustituye opcionalmente con fenilo, en donde fenilo se sustituye opcionalmente con sustituyentes independientemente seleccionados del grupo que consiste de halógeno, alquilo C1-4, alcoxi C1-4, amino, nitro y ciano. 3.- La composición de la reivindicación 2, en donde dicho compuesto es éster de ácido 2-(2-cloro-fenil)-2-hidroxi- etil carbámico. 4.- La composición de la reivindicación 2, en donde dicho compuesto es éster de ácido (2R)2-(2-cloro-fenil)-2- hidroxi-etil carbámico. 5.- La composición de la reivindicación 4, en donde dicho compuesto predomina en un rango de aproximadamente 75% o mayor; o en un rango de aproximadamente 90% o mayor; o en un rango de aproximadamente 95% o mayor; o en un rango de aproximadamente 98% o mayor; o en un rango de aproximadamente 99% o mayor. 6.- La composición de la reivindicación 2, en donde dicho compuesto es éster de ácido (2S)-2-(2-cloro-fenil)-2- hidroxi-etil carbámico. 7.- La composición de la reivindicación 6, en donde dicho compuesto predomina en un rango de aproximadamente 75% o mayor; o en un rango de aproximadamente 90% o mayor; o en un rango de aproximadamente 95% o mayor; o en un rango de aproximadamente 98% o mayor; o en un rango de aproximadamente 99% o mayor.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US82935506P | 2006-10-13 | 2006-10-13 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CO6190539A2 true CO6190539A2 (es) | 2010-08-19 |
Family
ID=39111848
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CO09037411A CO6190539A2 (es) | 2006-10-13 | 2009-04-14 | Composiciones de carbamato fenilalquilo |
Country Status (23)
| Country | Link |
|---|---|
| US (1) | US20080090903A1 (es) |
| EP (1) | EP2089002A1 (es) |
| JP (1) | JP2010506846A (es) |
| KR (1) | KR20090067210A (es) |
| CN (1) | CN101663026A (es) |
| AR (1) | AR063294A1 (es) |
| AU (1) | AU2007313018A1 (es) |
| BR (1) | BRPI0719236A2 (es) |
| CA (1) | CA2673526A1 (es) |
| CL (1) | CL2007002943A1 (es) |
| CO (1) | CO6190539A2 (es) |
| CR (1) | CR10793A (es) |
| EA (1) | EA200970378A1 (es) |
| IL (1) | IL198144A0 (es) |
| MX (1) | MX2009003929A (es) |
| NI (1) | NI200900055A (es) |
| NO (1) | NO20091492L (es) |
| PE (1) | PE20080887A1 (es) |
| SV (1) | SV2009003222A (es) |
| TW (1) | TW200831134A (es) |
| UY (1) | UY30643A1 (es) |
| WO (1) | WO2008048802A1 (es) |
| ZA (1) | ZA200903284B (es) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8263652B2 (en) | 2007-10-31 | 2012-09-11 | Sk Biopharmaceuticals Co., Ltd. | Stabilized pediatric suspension of carisbamate |
| JP5774694B2 (ja) * | 2010-07-02 | 2015-09-09 | バイオ−ファーム ソリューションズ カンパニー リミテッド | フェニルカルバメート化合物およびこれを含む筋肉弛緩剤 |
| US9018253B2 (en) | 2010-07-02 | 2015-04-28 | Bio-Pharm Solutions Co., Ltd. | Phenylcarbamate compound and muscle relaxant containing the same |
| US8609849B1 (en) | 2010-11-30 | 2013-12-17 | Fox Chase Chemical Diversity Center, Inc. | Hydroxylated sulfamides exhibiting neuroprotective action and their method of use |
| EP2797880B1 (en) | 2011-12-27 | 2017-03-01 | Bio-Pharm Solutions Co., Ltd. | Phenyl carbamate compounds for use in preventing or treating epilepsy |
| WO2014097137A2 (en) * | 2012-12-18 | 2014-06-26 | Mahesh Kandula | Compositions and methods for the treatment of seizures and neurologic diseases |
| CN105228604A (zh) | 2013-03-12 | 2016-01-06 | 比皮艾思药物研发有限公司 | 用于预防或治疗小儿癫痫和癫痫相关综合征的苯基氨基甲酸酯化合物 |
| EP2970110A4 (en) * | 2013-03-12 | 2016-12-28 | Bio-Pharm Solutions Co Ltd | PHENYL CARBAMATE COMPOUND AND COMPOSITION FOR PREVENTING OR TREATING PSYCHIATRIC DISORDER COMPRISING SAME |
| US11168052B2 (en) | 2016-02-29 | 2021-11-09 | Bio-Pharm Solutions Co., Ltd. | Carbamate derivative compounds, processes for preparing them and their uses |
| CA3016253C (en) * | 2016-02-29 | 2020-12-29 | Bio-Pharm Solutions Co., Ltd. | Sulfamate derivative compounds, processes for preparing them and their uses |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3265728A (en) * | 1962-07-18 | 1966-08-09 | Armour Pharma | Substituted phenethyl carbamates |
| US20010034365A1 (en) * | 1996-01-16 | 2001-10-25 | Choi Yong Moon | Halogen substituted carbamate compounds from 2-phenyl-1,2-ethanediol |
| US5698588A (en) * | 1996-01-16 | 1997-12-16 | Yukong Limited | Halogen substituted carbamate compounds from 2-phenyl-1,2-ethanediol |
| FR2758459B1 (fr) * | 1997-01-17 | 1999-05-07 | Pharma Pass | Composition pharmaceutique de fenofibrate presentant une biodisponibilite elevee et son procede de preparation |
| US20020147229A1 (en) * | 2000-08-17 | 2002-10-10 | Allerton Charlotte Moira Norfor | Pharmaceuticals |
| EP1450783A1 (en) * | 2001-10-08 | 2004-09-01 | Sun Pharmaceuticals Industries Ltd. | New anti-asthmatic drug (asmakure) from indigenous herbs to cure the disease asthma |
-
2007
- 2007-10-08 EA EA200970378A patent/EA200970378A1/ru unknown
- 2007-10-08 KR KR1020097009746A patent/KR20090067210A/ko not_active Application Discontinuation
- 2007-10-08 AU AU2007313018A patent/AU2007313018A1/en not_active Abandoned
- 2007-10-08 JP JP2009532515A patent/JP2010506846A/ja active Pending
- 2007-10-08 CA CA002673526A patent/CA2673526A1/en not_active Abandoned
- 2007-10-08 WO PCT/US2007/080677 patent/WO2008048802A1/en active Application Filing
- 2007-10-08 MX MX2009003929A patent/MX2009003929A/es unknown
- 2007-10-08 CN CN200780045911A patent/CN101663026A/zh active Pending
- 2007-10-08 BR BRPI0719236-3A patent/BRPI0719236A2/pt not_active IP Right Cessation
- 2007-10-08 US US11/868,588 patent/US20080090903A1/en not_active Abandoned
- 2007-10-08 EP EP07843959A patent/EP2089002A1/en not_active Withdrawn
- 2007-10-12 AR ARP070104554A patent/AR063294A1/es not_active Application Discontinuation
- 2007-10-12 PE PE2007001383A patent/PE20080887A1/es not_active Application Discontinuation
- 2007-10-12 TW TW096138084A patent/TW200831134A/zh unknown
- 2007-10-12 UY UY30643A patent/UY30643A1/es unknown
- 2007-10-12 CL CL200702943A patent/CL2007002943A1/es unknown
-
2009
- 2009-04-13 NI NI200900055A patent/NI200900055A/es unknown
- 2009-04-14 SV SV2009003222A patent/SV2009003222A/es unknown
- 2009-04-14 CO CO09037411A patent/CO6190539A2/es not_active Application Discontinuation
- 2009-04-16 IL IL198144A patent/IL198144A0/en unknown
- 2009-04-16 NO NO20091492A patent/NO20091492L/no not_active Application Discontinuation
- 2009-05-12 ZA ZA200903284A patent/ZA200903284B/xx unknown
- 2009-05-13 CR CR10793A patent/CR10793A/es not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| WO2008048802A1 (en) | 2008-04-24 |
| NI200900055A (es) | 2010-02-01 |
| ZA200903284B (en) | 2010-07-28 |
| AU2007313018A1 (en) | 2008-04-24 |
| JP2010506846A (ja) | 2010-03-04 |
| CN101663026A (zh) | 2010-03-03 |
| CA2673526A1 (en) | 2008-04-24 |
| MX2009003929A (es) | 2009-06-26 |
| IL198144A0 (en) | 2009-12-24 |
| UY30643A1 (es) | 2008-05-02 |
| EP2089002A1 (en) | 2009-08-19 |
| SV2009003222A (es) | 2009-10-15 |
| CR10793A (es) | 2009-09-29 |
| EA200970378A1 (ru) | 2009-10-30 |
| BRPI0719236A2 (pt) | 2014-07-08 |
| TW200831134A (en) | 2008-08-01 |
| AR063294A1 (es) | 2009-01-21 |
| NO20091492L (no) | 2009-07-09 |
| US20080090903A1 (en) | 2008-04-17 |
| PE20080887A1 (es) | 2008-06-28 |
| KR20090067210A (ko) | 2009-06-24 |
| CL2007002943A1 (es) | 2008-04-18 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CO6190539A2 (es) | Composiciones de carbamato fenilalquilo | |
| CO6180500A2 (es) | Composiciones de fenilalquilamino-carbamato | |
| UY28877A1 (es) | Compuestos de metil-aril o heteroaril-amida sustituida y composiciones | |
| AR083542A1 (es) | Piperidin-4-il-azetidin diamidas como inhibidores de monoacilglicerol lipasa | |
| AR054551A1 (es) | Metodos para la neuroproteccion | |
| GT200500102A (es) | Compuestos de aril-o-heteroarilamida ortosustituidos | |
| AR036079A1 (es) | Compuestos de [n-benzoil]-fenilsulfonamida y de n-[fenilsulfonil]-benzamidina;metodos para tratar neoplasias en mamiferos susceptibles, utilizando dichos compuestos y composiciones formuladas con dichos compuestos aplicables en los metodos mencionados | |
| RS51210B (sr) | Dobijanje pregaballina i srodnih jedinjenja | |
| PE20090042A1 (es) | Analogos de ciclopamina | |
| UY25204A1 (es) | Agonistas de prostaglandinas útiles en el tratamiento de desórdenes óseos | |
| PE20000543A1 (es) | Composiciones estabilizadas de quinapril y procedimiento para prepararlas | |
| PE20081354A1 (es) | Compuestos de azaindolilo como inhibidores de mek | |
| PE20170247A1 (es) | Derivados de pirrolidina-2,5-diona, composiciones farmaceuticas y metodos para usar como inhibidores ido1 | |
| BRPI0518642A2 (pt) | anÁlogos de 12-aril prostaglandina | |
| PE20140918A1 (es) | Compuestos de benzoxepina inhibidores de la pi3k | |
| AR083180A1 (es) | Amidas de oxopiperazina-azetidina y amidas oxodiazepina-azetidina como inhibidores de monoacilglicerol lipasa | |
| JP2007535559A5 (es) | ||
| CO5601006A2 (es) | Procedimiento para la preparacion de esteres de escopina | |
| PE20070833A1 (es) | Compuestos de pirimidinil benzotiofeno | |
| EA200701536A1 (ru) | Способы контроля интервала qt | |
| NO20080739L (no) | Fremgangsmater for behandling av Epileptogenese | |
| NO20063662L (no) | Benzimidazolderivater | |
| AR033426A1 (es) | Uso de compuestos carbamatos en la prevencion o el tratamiento de trastornos de movimiento | |
| UY38941A (es) | Nuevas sulfiliminas o sulfoximinas que contienen compuestos heterocíclicos fungicidas | |
| JOP20220124A1 (ar) | مشتقات 1، 2، 4-أوكساديازول كناهضات مستقبلات الكبد x |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC | Application refused |