CO5251435A1 - Composicion orales estables de liberacion extendida que comprenden un nucleo de pseudoefedrina, una capa de separacion y una capa de desloratadina - Google Patents
Composicion orales estables de liberacion extendida que comprenden un nucleo de pseudoefedrina, una capa de separacion y una capa de desloratadinaInfo
- Publication number
- CO5251435A1 CO5251435A1 CO00096727A CO00096727A CO5251435A1 CO 5251435 A1 CO5251435 A1 CO 5251435A1 CO 00096727 A CO00096727 A CO 00096727A CO 00096727 A CO00096727 A CO 00096727A CO 5251435 A1 CO5251435 A1 CO 5251435A1
- Authority
- CO
- Colombia
- Prior art keywords
- desloratadine
- layer
- hours
- extended release
- pseudoefedrine
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
- A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/04—Antipruritics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/14—Decongestants or antiallergics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Pulmonology (AREA)
- Dermatology (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Ophthalmology & Optometry (AREA)
- Toxicology (AREA)
- Otolaryngology (AREA)
- Immunology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Cosmetics (AREA)
- Toys (AREA)
Abstract
Se describe una composición para dosis oral sólida de liberación extendida revestida con un película que contiene un descongestivo nasal, pseudoefedrina o su sal, por ejemplo, sulfato de pseudoefedrina en un núcleo efectivo como para proporcionar una concentración en plasma máxima geométrica de pseudoefedrina entre alrededor de 345 ng/ml y alrededor de 365 ng/ml en un tiempo entre alrededor de 7,60 horas y alrededor de 8,40 horas y que tiene dos o tres revestimientos de película sobre el núcleo, el segundo contiene una cantidad de antihistamina, no sedativa, desloratadina, efectiva como para proporcionar una concentración en plasma máximo geométrica de desloratadina entre alrededor de 2,15 ng/ml y alrededor de 2,45 ng/ml en un tiempo entre alrededor de 4,0 horas y alrededor de 4,5 horas, y el uso de la composición para tratar pacientes que muestran signos y síntomas asociados con las condiciones alérgicas y/o inflamatorias de la piel y de las vías aéreas.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US17283699P | 1999-12-20 | 1999-12-20 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CO5251435A1 true CO5251435A1 (es) | 2003-02-28 |
Family
ID=22629437
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CO00096727A CO5251435A1 (es) | 1999-12-20 | 2000-12-20 | Composicion orales estables de liberacion extendida que comprenden un nucleo de pseudoefedrina, una capa de separacion y una capa de desloratadina |
Country Status (38)
| Country | Link |
|---|---|
| US (2) | US6979463B2 (es) |
| EP (2) | EP2196195A3 (es) |
| JP (3) | JP5042403B2 (es) |
| KR (2) | KR100936572B1 (es) |
| CN (3) | CN1211079C (es) |
| AR (1) | AR027033A1 (es) |
| AT (1) | ATE463240T1 (es) |
| AU (4) | AU2277101A (es) |
| BR (1) | BR0006403A (es) |
| CA (1) | CA2329217C (es) |
| CO (1) | CO5251435A1 (es) |
| CY (1) | CY1110693T1 (es) |
| CZ (1) | CZ302860B6 (es) |
| DE (1) | DE60044117D1 (es) |
| DK (1) | DK1112738T3 (es) |
| EC (1) | ECSP003836A (es) |
| EG (1) | EG23759A (es) |
| ES (1) | ES2341751T3 (es) |
| HK (1) | HK1034453A1 (es) |
| HU (1) | HUP0004988A3 (es) |
| ID (1) | ID28675A (es) |
| IL (1) | IL140450A (es) |
| MX (1) | MXPA00013037A (es) |
| MY (1) | MY130773A (es) |
| NO (1) | NO331645B1 (es) |
| NZ (1) | NZ509028A (es) |
| PE (1) | PE20010982A1 (es) |
| PL (1) | PL211573B1 (es) |
| PT (1) | PT1112738E (es) |
| RU (2) | RU2303440C2 (es) |
| SA (2) | SA01210741B1 (es) |
| SG (1) | SG109438A1 (es) |
| SI (1) | SI1112738T1 (es) |
| SK (1) | SK287684B6 (es) |
| TR (1) | TR200003787A3 (es) |
| TW (1) | TWI225414B (es) |
| WO (1) | WO2001045668A2 (es) |
| ZA (1) | ZA200007715B (es) |
Families Citing this family (38)
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| WO2001045668A2 (en) | 1999-12-20 | 2001-06-28 | Schering Corporation | Stable extended release oral dosage composition comprising pseudoephedrine and desloratadine |
| WO2001045676A2 (en) | 1999-12-20 | 2001-06-28 | Schering Corporation | Extended release oral dosage composition |
| US7405223B2 (en) | 2000-02-03 | 2008-07-29 | Schering Corporation | Treating allergic and inflammatory conditions |
| US20030070584A1 (en) | 2001-05-15 | 2003-04-17 | Cynthia Gulian | Dip coating compositions containing cellulose ethers |
| HUP0401630A2 (hu) * | 2001-06-20 | 2004-12-28 | Schering Corp. | Antihisztaminok alkalmazása nazális vérbőség és orrdugulás kezelésére szolgáló gyógyszerkészítmény előállítására |
| US8309118B2 (en) | 2001-09-28 | 2012-11-13 | Mcneil-Ppc, Inc. | Film forming compositions containing sucralose |
| US8323692B2 (en) | 2002-02-21 | 2012-12-04 | Valeant International Bermuda | Controlled release dosage forms |
| US7780987B2 (en) * | 2002-02-21 | 2010-08-24 | Biovail Laboratories International Srl | Controlled release dosage forms |
| ATE352305T1 (de) * | 2003-03-12 | 2007-02-15 | Teva Pharma | Stabile pharmazeutische zusammensetzungen mit desloratadine |
| US20050013863A1 (en) | 2003-07-18 | 2005-01-20 | Depomed, Inc., A Corporation Of The State Of California | Dual drug dosage forms with improved separation of drugs |
| WO2005053599A1 (ja) * | 2003-12-01 | 2005-06-16 | Takeda Pharmaceutical Company Limited | 固形製剤の印刷前処理方法及び印刷前処理方法が施された固形製剤 |
| WO2006047427A1 (en) * | 2004-10-25 | 2006-05-04 | Schering Corporation | M1 and/or m3 receptor antagonists in combination with other actives for treating respiratory disorders |
| US20060252830A1 (en) * | 2005-05-06 | 2006-11-09 | Brandon Stephen F | Method for the treatment of magnesium and potassium deficiencies |
| US20060252831A1 (en) * | 2005-05-06 | 2006-11-09 | Christopher Offen | Method for the treatment of magnesium and potassium deficiencies |
| US20070014855A1 (en) * | 2005-07-12 | 2007-01-18 | Rahul Gawande S | Stable desloratadine compositions |
| US20070036859A1 (en) * | 2005-08-11 | 2007-02-15 | Perry Ronald L | Sustained release antihistamine and decongestant composition |
| US8000981B2 (en) | 2005-11-30 | 2011-08-16 | The Invention Science Fund I, Llc | Methods and systems related to receiving nutraceutical associated information |
| US7974856B2 (en) | 2005-11-30 | 2011-07-05 | The Invention Science Fund I, Llc | Computational systems and methods related to nutraceuticals |
| US7927787B2 (en) | 2006-06-28 | 2011-04-19 | The Invention Science Fund I, Llc | Methods and systems for analysis of nutraceutical associated components |
| US20080103746A1 (en) | 2005-11-30 | 2008-05-01 | Searete Llc, A Limited Liability Corporation | Systems and methods for pathogen detection and response |
| US10296720B2 (en) | 2005-11-30 | 2019-05-21 | Gearbox Llc | Computational systems and methods related to nutraceuticals |
| US7827042B2 (en) | 2005-11-30 | 2010-11-02 | The Invention Science Fund I, Inc | Methods and systems related to transmission of nutraceutical associated information |
| US8297028B2 (en) | 2006-06-14 | 2012-10-30 | The Invention Science Fund I, Llc | Individualized pharmaceutical selection and packaging |
| US8340944B2 (en) | 2005-11-30 | 2012-12-25 | The Invention Science Fund I, Llc | Computational and/or control systems and methods related to nutraceutical agent selection and dosing |
| FR2894143B1 (fr) | 2005-12-01 | 2008-05-02 | Pierre Fabre Medicament Sa | Composition a liberation prolongee de l'actif, son procede de preparation et son utilisation. |
| CL2007001584A1 (es) * | 2006-06-01 | 2008-01-25 | Msd Consumer Care Inc | Composicion farmaceutica que comprende: un nucleo con fenilefrina en forma de liberacion inmediata y una capa erosionable que comprende fenilefrina y una matriz de liberacion sostenida; util para tratar los sintomas del resfriado, influenza, alergias o rinitis no alergicas. |
| NZ573174A (en) * | 2006-06-01 | 2012-01-12 | Msd Consumer Care Inc | Sustained release pharmaceutical dosage form containing phenylephrine |
| MX2008015357A (es) * | 2006-06-01 | 2009-03-06 | Schering Corp | Formulaciones de liberacion pulsada de fenilefrina y composiciones farmaceuticas. |
| EP2029114B1 (en) * | 2006-06-01 | 2014-09-24 | Merck Sharp & Dohme Corp. | Pharmaceutical compositions for sustained release of phenylephrine |
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| US7405223B2 (en) | 2000-02-03 | 2008-07-29 | Schering Corporation | Treating allergic and inflammatory conditions |
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-
2000
- 2000-12-19 WO PCT/US2000/034412 patent/WO2001045668A2/en active Application Filing
- 2000-12-19 SK SK1967-2000A patent/SK287684B6/sk not_active IP Right Cessation
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