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CO5040091A1 - UREA DERIVATIVES - Google Patents

UREA DERIVATIVES

Info

Publication number
CO5040091A1
CO5040091A1 CO96050316A CO96050316A CO5040091A1 CO 5040091 A1 CO5040091 A1 CO 5040091A1 CO 96050316 A CO96050316 A CO 96050316A CO 96050316 A CO96050316 A CO 96050316A CO 5040091 A1 CO5040091 A1 CO 5040091A1
Authority
CO
Colombia
Prior art keywords
urea derivatives
alkyl
hydrogen
trifluoromethyl
alkoxy
Prior art date
Application number
CO96050316A
Other languages
Spanish (es)
Inventor
Christopher Simon John Walpole
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Ag filed Critical Sandoz Ag
Publication of CO5040091A1 publication Critical patent/CO5040091A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C275/28—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C275/32—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by singly-bound oxygen atoms
    • C07C275/34—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by singly-bound oxygen atoms having nitrogen atoms of urea groups and singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C275/04—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms
    • C07C275/20—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms of an unsaturated carbon skeleton
    • C07C275/24—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C275/28—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C275/28—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C275/30—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by halogen atoms, or by nitro or nitroso groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Un compuesto de fórmula Icaracterizada porqueR1 es alquilo de C1-4 , alcoxi de C1-4 , halógeno o trifluorometilo,R2 es hidrógeno o tiene cualquiera de los significados indicados para R1 R3 es hidrógeno o alquilo de C1-4 , yn es cero, 1 ó 2o una amida o sal del mismo fisiológicamente hidrolizable y aceptable.A compound of formula I characterized in that R1 is C1-4 alkyl, C1-4 alkoxy, halogen or trifluoromethyl, R2 is hydrogen or has any of the meanings indicated for R1 R3 is hydrogen or C1-4 alkyl, and n is zero, 1 or 2o a physiologically hydrolysable and acceptable amide or salt thereof.

CO96050316A 1995-09-21 1996-09-20 UREA DERIVATIVES CO5040091A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB9519270.4A GB9519270D0 (en) 1995-09-21 1995-09-21 Organic compounds

Publications (1)

Publication Number Publication Date
CO5040091A1 true CO5040091A1 (en) 2001-05-29

Family

ID=10781041

Family Applications (1)

Application Number Title Priority Date Filing Date
CO96050316A CO5040091A1 (en) 1995-09-21 1996-09-20 UREA DERIVATIVES

Country Status (5)

Country Link
AU (1) AU7131596A (en)
CO (1) CO5040091A1 (en)
GB (1) GB9519270D0 (en)
WO (1) WO1997011052A1 (en)
ZA (1) ZA967997B (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6255349B1 (en) 1998-12-09 2001-07-03 American Home Products Corporation Alph-methylbenzyl-containing thiourea inhibitors of herpes viruses containing a phenylenediamine group
KR20010089551A (en) * 1998-12-09 2001-10-06 이곤 이 버그 Alpha-methylbenzyl-containing thiourea inhibitors of herpes viruses containing a phenylenediamine group
US6207715B1 (en) 1998-12-09 2001-03-27 American Home Products Corporation Alpha-methylbenzyl-containing thiourea inhibitors of herpes viruses containing a substituted phenylene-diamine group
JP2002531545A (en) * 1998-12-09 2002-09-24 ワイス Herpesvirus thiourea inhibitors
GB0105895D0 (en) * 2001-03-09 2001-04-25 Smithkline Beecham Plc Novel compounds
EP1939173A1 (en) * 2006-12-21 2008-07-02 Pharmeste S.r.l. O-substituted-dibenzyl urea- or thiourea- derivatives as trpv1 receptor antagonists

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4460602A (en) * 1981-06-30 1984-07-17 The Procter & Gamble Company Urea derivatives
DE3887544T2 (en) * 1987-03-09 1994-06-01 Procter & Gamble Beta-aminoethyl-substituted phenyl compounds, anti-inflammatory or analgesic compositions containing them.
HU206082B (en) * 1988-12-23 1992-08-28 Sandoz Ag Process for producing capsaicin derivatives and pharmaceutical compositions comprising such compounds
HU210683B (en) * 1990-06-18 1995-06-28 Sandoz Ag Process for producing n-benzyl-n1-(phenyl-alkyl)-thiourea derivatives and pharmaceutical compositions containing the same

Also Published As

Publication number Publication date
GB9519270D0 (en) 1995-11-22
WO1997011052A1 (en) 1997-03-27
ZA967997B (en) 1998-03-20
AU7131596A (en) 1997-04-09

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