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CO4910151A1 - A LONG-ACTING PARASITICIDE INJECTABLE COMPOSITION AND PROCEDURE FOR PREPARING IT - Google Patents

A LONG-ACTING PARASITICIDE INJECTABLE COMPOSITION AND PROCEDURE FOR PREPARING IT

Info

Publication number
CO4910151A1
CO4910151A1 CO97045239A CO97045239A CO4910151A1 CO 4910151 A1 CO4910151 A1 CO 4910151A1 CO 97045239 A CO97045239 A CO 97045239A CO 97045239 A CO97045239 A CO 97045239A CO 4910151 A1 CO4910151 A1 CO 4910151A1
Authority
CO
Colombia
Prior art keywords
preparing
procedure
long
invermectin
mixture
Prior art date
Application number
CO97045239A
Other languages
Spanish (es)
Inventor
Jorge Carlos Lamberti
Original Assignee
Biogenesis S A
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biogenesis S A filed Critical Biogenesis S A
Publication of CO4910151A1 publication Critical patent/CO4910151A1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

Una composición parasiticida inyectable larga accióncaracterizada porque comprende invermectina en una concentración del 1% (p/p), alcohol bencílico, polivinil pirrolidona, N-metil-2-pirrolidona en una proporción de entre 40-65% (v/p) del total de la formulación, adyuvantes y glicerina hasta alcanzar el 100% de peso final.Procedimiento para preparar una composición parasiticida inyectable de invermectina caracterizado porque comprende mezclar invermectina en cantidad suficiente para lograr una concentración final del 1% (p/p) con alcohol bencílico y polivinil pirrolidona, agregar a dicha mezcla adyuvantes, seguido de adición de la mezcla a N-metil-2-pirrolidona, este último en una proporción de entre 40-65% (v/p) del total de la formulación; se agita la mezcla hasta disolución total y se agrega glicerina hasta alcanzar el 100% de peso final.A long-acting injectable parasiticidal composition characterized in that it comprises invermectin in a concentration of 1% (w / w), benzyl alcohol, polyvinyl pyrrolidone, N-methyl-2-pyrrolidone in a proportion of between 40-65% (v / w) of the total of the formulation, adjuvants and glycerin until reaching 100% final weight.Procedure for preparing an injectable parasiticidal composition of invermectin characterized in that it comprises mixing invermectin in sufficient quantity to achieve a final concentration of 1% (w / w) with benzyl alcohol and polyvinyl pyrrolidone, add adjuvants to said mixture, followed by adding the mixture to N-methyl-2-pyrrolidone, the latter in a proportion of between 40-65% (v / w) of the total formulation; the mixture is stirred until complete dissolution and glycerin is added until reaching 100% of final weight.

CO97045239A 1997-03-21 1997-08-06 A LONG-ACTING PARASITICIDE INJECTABLE COMPOSITION AND PROCEDURE FOR PREPARING IT CO4910151A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ARP970107144 1997-03-21

Publications (1)

Publication Number Publication Date
CO4910151A1 true CO4910151A1 (en) 2000-04-24

Family

ID=40933913

Family Applications (1)

Application Number Title Priority Date Filing Date
CO97045239A CO4910151A1 (en) 1997-03-21 1997-08-06 A LONG-ACTING PARASITICIDE INJECTABLE COMPOSITION AND PROCEDURE FOR PREPARING IT

Country Status (3)

Country Link
BR (1) BR9705242B1 (en)
CO (1) CO4910151A1 (en)
UY (1) UY24620A1 (en)

Also Published As

Publication number Publication date
UY24620A1 (en) 1997-12-31
BR9705242B1 (en) 2011-05-31
BR9705242A (en) 2000-12-19

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