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CO2018012113A2 - Composiciones de múltiples dosis que contienen un conservador de poliamida antimicrobiana u octenidina - Google Patents

Composiciones de múltiples dosis que contienen un conservador de poliamida antimicrobiana u octenidina

Info

Publication number
CO2018012113A2
CO2018012113A2 CONC2018/0012113A CO2018012113A CO2018012113A2 CO 2018012113 A2 CO2018012113 A2 CO 2018012113A2 CO 2018012113 A CO2018012113 A CO 2018012113A CO 2018012113 A2 CO2018012113 A2 CO 2018012113A2
Authority
CO
Colombia
Prior art keywords
octenidine
preservative
compositions containing
dose compositions
antimicrobial polyamide
Prior art date
Application number
CONC2018/0012113A
Other languages
English (en)
Inventor
Guillaume Rigaut
Celine Loss-Dunod
Alexis Guy Andre Lucien Parisot
Pradeep K Dahl
Original Assignee
Genzyme Corp
Merial Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genzyme Corp, Merial Inc filed Critical Genzyme Corp
Publication of CO2018012113A2 publication Critical patent/CO2018012113A2/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/444—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/785—Polymers containing nitrogen
    • A61K31/787—Polymers containing nitrogen containing heterocyclic rings having nitrogen as a ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/04—Mycobacterium, e.g. Mycobacterium tuberculosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/186—Quaternary ammonium compounds, e.g. benzalkonium chloride or cetrimide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • A61K2039/552—Veterinary vaccine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55566—Emulsions, e.g. Freund's adjuvant, MF59
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/0241—Mollicutes, e.g. Mycoplasma, Erysipelothrix
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
    • C12N2750/00011—Details
    • C12N2750/10011—Circoviridae
    • C12N2750/10034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Mycology (AREA)
  • Virology (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Communicable Diseases (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Pulmonology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Inorganic Chemistry (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Medicinal Preparation (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Dermatology (AREA)

Abstract

RESUMEN DE LA INVENCIÓN La presente invención se relaciona a conservadores no mercuriales, que incluyen polímeros de poliamida antimicrobiana y octenidina, y a métodos de uso de los mismos para producir formulaciones de múltiples dosis que contienen conservador. Las formulaciones de múltiples dosis que contienen conservador exhiben resistencia a uno o más microorganismos contaminantes, y tienen propiedades ventajosas con respecto a la estabilidad a largo plazo de ingredientes activos biológicos y de molécula pequeña.
CONC2018/0012113A 2016-04-14 2018-11-09 Composiciones de múltiples dosis que contienen un conservador de poliamida antimicrobiana u octenidina CO2018012113A2 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201662322258P 2016-04-14 2016-04-14
PCT/US2017/027491 WO2017180916A1 (en) 2016-04-14 2017-04-13 Multi-dose compositions containing an antimicrobial polyamide or octenidine preservative

Publications (1)

Publication Number Publication Date
CO2018012113A2 true CO2018012113A2 (es) 2019-02-08

Family

ID=59215875

Family Applications (1)

Application Number Title Priority Date Filing Date
CONC2018/0012113A CO2018012113A2 (es) 2016-04-14 2018-11-09 Composiciones de múltiples dosis que contienen un conservador de poliamida antimicrobiana u octenidina

Country Status (14)

Country Link
US (1) US10583154B2 (es)
EP (1) EP3442587B1 (es)
JP (1) JP7089479B2 (es)
KR (1) KR20180129949A (es)
CN (1) CN109310776B (es)
AU (1) AU2017248674B2 (es)
BR (1) BR112018071125A8 (es)
CA (1) CA3020634A1 (es)
CL (1) CL2018002919A1 (es)
CO (1) CO2018012113A2 (es)
EA (1) EA039370B1 (es)
ES (1) ES2898798T3 (es)
MX (1) MX379091B (es)
WO (1) WO2017180916A1 (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20200383932A1 (en) * 2019-06-05 2020-12-10 The Florida International University Board Of Trustees Biotherapy for viral infections using biopolymer based micro/nanogels
US12263252B2 (en) 2019-06-05 2025-04-01 The Florida International University Board Of Trustees Biotherapy for viral infections using biopolymer based micro/nanogels

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK590288D0 (da) 1988-10-24 1988-10-24 Symbicom Ab Kemiske forbindelser
US2909462A (en) 1955-12-08 1959-10-20 Bristol Myers Co Acrylic acid polymer laxative compositions
US5777095A (en) 1988-10-24 1998-07-07 Symbicom Aktiebolag Osp A and B Sequence of Borrelia burgdonferi strains ACA1 and IP90
DE69733020T2 (de) 1996-10-11 2006-02-16 The Regents Of The University Of California, Oakland Immunostimulierende oligonucleotidekonjugate
ATE470434T1 (de) * 1997-02-06 2010-06-15 Merck Sharp & Dohme Thimerosal-freie konservierungsmittel für impfstoffe
US6368603B1 (en) 1997-03-05 2002-04-09 Merial Limited Lyme combination compositions and uses
AUPP584298A0 (en) * 1998-09-14 1998-10-08 Starpharma Limited Antimicrobial and antiparasitic agents
RU2195269C2 (ru) * 2001-02-14 2002-12-27 Общество с ограниченной ответственностью "МДТ" Витаминно-минеральный комплекс
DE10205883A1 (de) * 2002-02-13 2003-08-21 Schuelke & Mayr Gmbh Wässriges Antiseptikum auf Basis von Bispyridiniumalkanen
BRPI0412855B8 (pt) * 2003-07-24 2022-06-28 Merial Inc formulações de vacina
DE102005045145A1 (de) * 2005-09-15 2007-03-29 Schülke & Mayr GmbH Verwendung von Octenidindihydrochlorid in halbfesten Zubereitungen
CN101366945A (zh) * 2008-08-21 2009-02-18 浙江卫信生物药业有限公司 不含甲醛和硫柳汞的吸附白喉疫苗的配制方法
AU2011262309B2 (en) * 2010-06-01 2015-08-13 Seqirus UK Limited Concentration of influenza vaccine antigens without lyophilization
US9095567B2 (en) 2010-06-04 2015-08-04 Wyeth Llc Vaccine formulations
KR102233537B1 (ko) * 2013-03-15 2021-03-29 뵈링거 잉겔하임 애니멀 헬스 유에스에이 인코포레이티드 항균성 폴리아미드 조성물 및 유방염 치료

Also Published As

Publication number Publication date
BR112018071125A2 (pt) 2019-02-05
AU2017248674A1 (en) 2018-11-01
CN109310776A (zh) 2019-02-05
EA201892330A1 (ru) 2019-03-29
CA3020634A1 (en) 2017-10-19
CL2018002919A1 (es) 2019-01-18
KR20180129949A (ko) 2018-12-05
CN109310776B (zh) 2022-02-11
JP7089479B2 (ja) 2022-06-22
BR112018071125A8 (pt) 2022-06-28
US10583154B2 (en) 2020-03-10
WO2017180916A1 (en) 2017-10-19
US20170296577A1 (en) 2017-10-19
EP3442587A1 (en) 2019-02-20
JP2019513793A (ja) 2019-05-30
AU2017248674B2 (en) 2021-04-01
MX379091B (es) 2025-03-10
NZ747144A (en) 2024-12-20
EA039370B1 (ru) 2022-01-19
EP3442587B1 (en) 2021-08-18
ES2898798T3 (es) 2022-03-08
MX2018012477A (es) 2019-03-07

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