CO2018002428A2 - Amida seleccionada de ácido gamma-hidroxiburico y usos de la misma en el tratamiento de abuso de alcohol - Google Patents
Amida seleccionada de ácido gamma-hidroxiburico y usos de la misma en el tratamiento de abuso de alcoholInfo
- Publication number
- CO2018002428A2 CO2018002428A2 CONC2018/0002428A CO2018002428A CO2018002428A2 CO 2018002428 A2 CO2018002428 A2 CO 2018002428A2 CO 2018002428 A CO2018002428 A CO 2018002428A CO 2018002428 A2 CO2018002428 A2 CO 2018002428A2
- Authority
- CO
- Colombia
- Prior art keywords
- treatment
- alcohol abuse
- hydroxyiburic
- gamma
- acid
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/32—Alcohol-abuse
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C231/00—Preparation of carboxylic acid amides
- C07C231/02—Preparation of carboxylic acid amides from carboxylic acids or from esters, anhydrides, or halides thereof by reaction with ammonia or amines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
- C07C235/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton
- C07C235/04—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C235/06—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
- C07C235/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton
- C07C235/32—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton containing six-membered aromatic rings
- C07C235/34—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton containing six-membered aromatic rings having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Engineering & Computer Science (AREA)
- Neurosurgery (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Addiction (AREA)
- Psychiatry (AREA)
- Epidemiology (AREA)
- Anesthesiology (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
La presente invención se relaciona con una amida seleccionada de ácido y-hidroxibutírico, un proceso de elaboración y usos de los mismos. La invención también incluye una composición farmacéutica que comprende una cantidad eficaz del compuesto seleccionado de la invención para usarse en la prevención o tratamiento de adicción a drogas, especialmente abuso o dependencia al alcohol.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ITUB2015A002860A ITUB20152860A1 (it) | 2015-08-04 | 2015-08-04 | Selezionata amide dell?acido ?-idrossibutirrico e suoi usi nel trattamento dell?abuso da alcool |
| PCT/EP2016/068517 WO2017021438A1 (en) | 2015-08-04 | 2016-08-03 | SELECTED AMIDE OF γ -HYDROXYBUTYRIC ACID AND USES THEREOF IN THE TREATMENT OF ALCOHOL MISUSE |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CO2018002428A2 true CO2018002428A2 (es) | 2018-07-10 |
Family
ID=54542363
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CONC2018/0002428A CO2018002428A2 (es) | 2015-08-04 | 2018-03-02 | Amida seleccionada de ácido gamma-hidroxiburico y usos de la misma en el tratamiento de abuso de alcohol |
Country Status (23)
| Country | Link |
|---|---|
| US (1) | US10336687B2 (es) |
| EP (1) | EP3331853B1 (es) |
| JP (1) | JP6832336B2 (es) |
| KR (1) | KR20180066033A (es) |
| CN (1) | CN108026029B (es) |
| AU (1) | AU2016302869B2 (es) |
| CA (1) | CA2994599C (es) |
| CL (1) | CL2018000282A1 (es) |
| CO (1) | CO2018002428A2 (es) |
| DK (1) | DK3331853T3 (es) |
| EA (1) | EA033769B9 (es) |
| ES (1) | ES2776628T3 (es) |
| GE (1) | GEP20207107B (es) |
| IL (1) | IL257314B (es) |
| IT (1) | ITUB20152860A1 (es) |
| MX (1) | MX2018001239A (es) |
| MY (1) | MY185942A (es) |
| PH (1) | PH12018550008A1 (es) |
| PL (1) | PL3331853T3 (es) |
| PT (1) | PT3331853T (es) |
| UA (1) | UA121994C2 (es) |
| WO (1) | WO2017021438A1 (es) |
| ZA (1) | ZA201801402B (es) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2019025932A1 (en) * | 2017-07-31 | 2019-02-07 | Novartis Ag | USE OF MUSSELUROUS IN REDUCING THE USE OF ALCOHOL OR IN THE PREVENTION OF RECHUTE IN THE USE OF ALCOHOL |
| US11878001B2 (en) | 2017-07-31 | 2024-01-23 | Novartis Ag | Use of mavoglurant in the reduction of cocaine use or in preventing relapse into cocaine use |
| CN113185403A (zh) * | 2021-07-02 | 2021-07-30 | 山东国邦药业有限公司 | 一种甲醚制备环丙胺中间体环丙甲酸甲酯的方法 |
| WO2023126076A1 (en) * | 2022-01-03 | 2023-07-06 | Laboratorio Farmaceutico C.T. S.R.L. | Medical use of an amide of y-hydroxybutyric acid in the treatment of fragile x syndrome |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1283782B1 (it) * | 1996-08-09 | 1998-04-30 | Ct Lab Farm Srl | Uso di ammidi dell'acido gamma-idrossibutirrico nel trattamento di tossicodipendenze,ed in particolare sell'alcolismo |
-
2015
- 2015-08-04 IT ITUB2015A002860A patent/ITUB20152860A1/it unknown
-
2016
- 2016-08-03 WO PCT/EP2016/068517 patent/WO2017021438A1/en active Application Filing
- 2016-08-03 CA CA2994599A patent/CA2994599C/en active Active
- 2016-08-03 AU AU2016302869A patent/AU2016302869B2/en active Active
- 2016-08-03 DK DK16791313.6T patent/DK3331853T3/da active
- 2016-08-03 ES ES16791313T patent/ES2776628T3/es active Active
- 2016-08-03 UA UAA201801726A patent/UA121994C2/uk unknown
- 2016-08-03 EP EP16791313.6A patent/EP3331853B1/en active Active
- 2016-08-03 CN CN201680045364.9A patent/CN108026029B/zh active Active
- 2016-08-03 EA EA201890419A patent/EA033769B9/ru not_active IP Right Cessation
- 2016-08-03 US US15/750,047 patent/US10336687B2/en active Active
- 2016-08-03 PT PT167913136T patent/PT3331853T/pt unknown
- 2016-08-03 KR KR1020187006231A patent/KR20180066033A/ko active IP Right Grant
- 2016-08-03 JP JP2018502356A patent/JP6832336B2/ja active Active
- 2016-08-03 MX MX2018001239A patent/MX2018001239A/es active IP Right Grant
- 2016-08-03 GE GEAP201614717A patent/GEP20207107B/en unknown
- 2016-08-03 MY MYPI2018700405A patent/MY185942A/en unknown
- 2016-08-03 PL PL16791313T patent/PL3331853T3/pl unknown
-
2018
- 2018-01-31 CL CL2018000282A patent/CL2018000282A1/es unknown
- 2018-02-01 IL IL257314A patent/IL257314B/en active IP Right Grant
- 2018-02-02 PH PH12018550008A patent/PH12018550008A1/en unknown
- 2018-02-28 ZA ZA2018/01402A patent/ZA201801402B/en unknown
- 2018-03-02 CO CONC2018/0002428A patent/CO2018002428A2/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP3331853A1 (en) | 2018-06-13 |
| MX2018001239A (es) | 2018-07-06 |
| AU2016302869B2 (en) | 2020-10-22 |
| EA201890419A1 (ru) | 2018-07-31 |
| PL3331853T3 (pl) | 2020-06-15 |
| EA033769B9 (ru) | 2020-04-10 |
| CN108026029A (zh) | 2018-05-11 |
| ES2776628T3 (es) | 2020-07-31 |
| EA033769B1 (ru) | 2019-11-22 |
| JP6832336B2 (ja) | 2021-02-24 |
| BR112018002245A2 (pt) | 2018-09-18 |
| CA2994599A1 (en) | 2017-02-09 |
| CN108026029B (zh) | 2020-12-04 |
| WO2017021438A1 (en) | 2017-02-09 |
| ZA201801402B (en) | 2019-01-30 |
| KR20180066033A (ko) | 2018-06-18 |
| GEAP202014717A (en) | 2020-01-27 |
| PH12018550008A1 (en) | 2018-07-09 |
| UA121994C2 (uk) | 2020-08-25 |
| IL257314B (en) | 2020-04-30 |
| JP2018523644A (ja) | 2018-08-23 |
| GEP20207107B (en) | 2020-05-11 |
| IL257314A (en) | 2018-03-29 |
| US20180230086A1 (en) | 2018-08-16 |
| AU2016302869A1 (en) | 2018-03-15 |
| CL2018000282A1 (es) | 2018-07-13 |
| MY185942A (en) | 2021-06-14 |
| US10336687B2 (en) | 2019-07-02 |
| DK3331853T3 (da) | 2020-03-16 |
| PT3331853T (pt) | 2020-02-25 |
| CA2994599C (en) | 2023-08-29 |
| EP3331853B1 (en) | 2019-12-11 |
| ITUB20152860A1 (it) | 2017-02-04 |
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