CN2347170Y - General two-dimensional chromatography interface device - Google Patents
General two-dimensional chromatography interface device Download PDFInfo
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- CN2347170Y CN2347170Y CN 98239123 CN98239123U CN2347170Y CN 2347170 Y CN2347170 Y CN 2347170Y CN 98239123 CN98239123 CN 98239123 CN 98239123 U CN98239123 U CN 98239123U CN 2347170 Y CN2347170 Y CN 2347170Y
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- valve
- interface
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- gas chromatography
- chromatography
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Abstract
The utility model belongs to a material sample analyzing device which is an interface device between a liquid chromatography and a gas chromatography. The interface device is composed of an electromagnetic valve, a pressure regulating valve and a flow regulating valve, wherein, the control ends of the electromagnetic valve are connected with a controller, a precision pressure gauge is arranged between the electromagnetic valve and the pressure regulating valve whose back face is connected with the flow regulating valve, and finally, the output end of the flow regulating valve is connected with the gas chromatography. The utility model has the advantages that a general interface suitable for a two-dimensional chromatography has optional use modes and uses the combination of a conventional high efficiency liquid chromatography and a capillary gas chromatography as a main point, the interface can be used for the combination of a capillary liquid chromatography and the capillary gas chromatography, and meanwhile, the interface can realize the cutting and reverse blowing application of the two-dimensional gas chromatography and directly carry out the separating measurement of the gas chromatography with two columns connected in series.
Description
The utility model belongs to a kind of material sample analytical equipment.
Chromatogram is important compartment analysis means, in environmental science, natural products, has the effect that is difficult to substitute in the field such as petrochemical complex and biomedicine, particularly the development of capillary gas chromatography makes the analysis of complicated organic mixture that revolutionary variation take place, however, for complex mixture and have the sample of complicated substrate, sometimes only still can not reach well and separate with single-column list clastotype, automatic sampler is arranged at present, eluent sample introduction and gas mode transmission interface, they or service routine intensification injector, or use the retention gap technology to evaporate a large amount of solvents, make troubles for like this analysis of complex material.
For solving above deficiency, the purpose of this utility model provides a kind of Versatile two-dimension chromatogram interface arrangement, utilizes this interface can realize the two-dimensional gas chromatography separation determination, and can be advantageously used in the twin columns series connection gas chromatography.
Design proposal of the present utility model is achieved in that this interface is based on conventional high performance liquid chromatography and capillary gas chromatography coupling, also can be used for capillary liquid chromatography and capillary gas chromatography coupling, its interface arrangement is connected between liquid chromatography and the gas chromatography, detailed structure is that the top of liquid chromatography is a liquid chromatography pump, be gas admittance valve below, connect liquid-phase chromatographic column below the gas admittance valve, the bottom is the UV detecting device, detecting device output connects with intermediary interface, transfer valve is housed in interface, transfer valve connects with solenoid valve and column sample injection mouth respectively again, the solenoid control end connects with programming controller, solenoid valve connects with precision pressure gauge simultaneously, the back is connected in series pressure regulator valve again, flow regulating valve, another way solenoid valve back connects precision pressure gauge and pressure regulator valve, pressure regulator valve output connects flow regulating valve again respectively, solenoid valve is passed through in flow regulating valve output again, its output connects with gas chromatography, the solenoid control end connects with controller, the column sample injection mouth of intermediary interface, two solenoid valves output respectively with the retention gap post of form and aspect chromatogram, two zero volume threeways link, as shown in the figure, a is a liquid chromatography, b is an intermediary interface, and c is a gas chromatography, because intermediary interface organically connects liquid chromatography and gas chromatography.
The advantage of the utility model: the general-purpose interface of the two-dimentional chromatogram of a kind of suitable son, the use pattern of this interface can be selected, this interface is based on conventional high performance liquid chromatography and capillary gas chromatography coupling, and can be used for kapillary liquid phase look and become and the capillary gas chromatography coupling; Having used cutting that this interface can realize two-dimensional gas chromatography and blowback operation simultaneously and can directly carry out the twin columns string related phase chromatographic resolution measures, in this interface, designed a large amount of solvent emptying and solvent and purged cleaning function, can reduce in liquid chromatography and gas chromatography coupling solvent peak and trail and avoid a large amount of solvents to enter analytical column and detecting device and the drawback brought.
The detailed structure following examples and the accompanying drawing of the utility model provide.
Fig. 1 is a Versatile two-dimension chromatogram interface arrangement structure principle chart.
Its structure as shown in drawings, a. liquid chromatogram; B. interface; C. gas-chromatography; 1. liquid chromatography pump; 2. sample introduction Valve; 3. liquid-phase chromatographic column; 4.UV detector; 5. transfer valve; 6,9,16,21,22. magnetic valves; 7,10,15,20. essences Close Pressure gauge; 8,11,14,19. pressure regulator valves; 12,13,23. flow regulating valves; 17. column sample injection mouth; 24. cyclelog; 25. gas chromatographic sample introduction mouth; 26.FID; 27. retaining space post; 28. reservation guard column; 29. gas chromatographic column; 30,31. zero volume threeways. Fig. 1 illustrates liquid chromatogram and gas-chromatography to utilize flow process, if 28 become the another gas phase The chromatography post and will be connected in 30 one terminate to gas chromatographic sample introduction mouth 25, sample introduction just can carry out pair from here The post series connection is analyzed. By regulating the pressure that 19 and 23 valves just can whole 31 places, thereby the reservation that changes on two posts is big Little and regulate selectively, be changed to gas chromatographic column with 27,28 are changed to resisting force column and 27 entrances are connected to 25; Logical Cross 14,19 and regulate 30,31 pressure, switch with blowback through 21,16 controls and just can carry out two-dimensional gas chromatography Mensuration.
Embodiment
The two-dimentional chromatogram interface that utilizes us to develop selects liquid chromatography and gas chromatography to utilize operator scheme.The evaporating temperature of system, the factors such as pressure of retention gap post are being optimized on the basis, by the aftermentioned condition a kind of diesel oil is analyzed, sample introduction 5 μ L after former state is diluted 100 times with normal hexane make moving phase with hexane and separate through silicagel column, flow velocity 0.3mL/min, detection wavelength 254nm.Under following condition, carry out gas chromatographic analysis, 70 ℃ of solvent evaporation temperature, retention gap column pressure 0.2MPa; The column temperature program of analyzing fraction A for (time by the LC sample introduction time count) is: 70 ℃ keep 15min, rise to 250 ℃ of also maintenances with 15 ℃/min then; B and C cut then rise to 180 ℃ with 10 ℃/min and keep 5min behind 70 ℃ of maintenance 15min, rise to 250 ℃ and maintenance with 3 ℃/min again, we know, be difficult to directly measure micro-aromatic hydrocarbons in the n-alkane with GC, and just can easily this be analyzed with said system, this system of coupling to AN32 lubricating oil analysis result is: non-aromatics 92.6%, aromatic hydrocarbons 7.4%; And by ASTM D2549-81 measurement result be: non-aromatics 92.9%, aromatic hydrocarbons 7.1%.Therefore visible the two is very consistent, saves time manyly but this method is easy, in addition, utilizes this interface to carry out two peacekeeping twin columns series connection gas chromatographic analysis and VOC ' s in many complex samples such as the environment is measured its result can improve greatly.
Claims (1)
1. Versatile two-dimension chromatogram interface arrangement, it is characterized in that this installs its structure is that the top of liquid chromatography is liquid chromatography pump (1), be gas admittance valve (2) below, connect liquid-phase chromatographic column (3) below the gas admittance valve, the bottom is UV detecting device (4), detecting device output connects with intermediary interface, transfer valve (5) is housed in interface, transfer valve (5) connects with solenoid valve (9) and column sample injection mouth (17) respectively again, solenoid valve (9) control end connects with programming controller (25), solenoid valve connects with precision pressure gauge (10) simultaneously, the back is connected in series pressure regulator valve (11) again, flow regulating valve (12), another way solenoid valve back connects precision pressure gauge (7) and pressure regulator valve (8), pressure regulator valve output connects flow regulating valve (13) (18) again respectively, solenoid valve (16) is passed through in flow regulating valve output again, its output connects with gas chromatography, solenoid control end (16) (21) connects with controller (25), the column sample injection mouth of intermediary interface, two solenoid valves output respectively with the retention gap post (27) of form and aspect chromatogram, two zero volume threeways (30) (31) link.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 98239123 CN2347170Y (en) | 1998-10-21 | 1998-10-21 | General two-dimensional chromatography interface device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 98239123 CN2347170Y (en) | 1998-10-21 | 1998-10-21 | General two-dimensional chromatography interface device |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN2347170Y true CN2347170Y (en) | 1999-11-03 |
Family
ID=33986557
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 98239123 Expired - Fee Related CN2347170Y (en) | 1998-10-21 | 1998-10-21 | General two-dimensional chromatography interface device |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN2347170Y (en) |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101169391B (en) * | 2006-10-25 | 2011-01-19 | 中国科学院大连化学物理研究所 | Two-dimensional highly effective liquid phase chromatographic system and its uses |
| CN101271094B (en) * | 2008-05-15 | 2011-06-01 | 宁波科宁达工业有限公司 | Zwitterion analysis system of ion chromatographic instrument |
| CN101218505B (en) * | 2005-05-20 | 2012-08-08 | 卡斯蒂利亚-拉曼查大学 | Interphase injector device for the direct coupling of liquid chromatography and gas chromatography |
| CN103189119A (en) * | 2010-10-29 | 2013-07-03 | 赛默菲尼根有限责任公司 | Method and system for liquid chromatograph with compressibility and viscosity monitoring to identify fluids |
| CN106872623A (en) * | 2015-12-11 | 2017-06-20 | 中国科学院大连化学物理研究所 | A kind of two-dimensional gas chromatography interface |
-
1998
- 1998-10-21 CN CN 98239123 patent/CN2347170Y/en not_active Expired - Fee Related
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101218505B (en) * | 2005-05-20 | 2012-08-08 | 卡斯蒂利亚-拉曼查大学 | Interphase injector device for the direct coupling of liquid chromatography and gas chromatography |
| CN101169391B (en) * | 2006-10-25 | 2011-01-19 | 中国科学院大连化学物理研究所 | Two-dimensional highly effective liquid phase chromatographic system and its uses |
| CN101271094B (en) * | 2008-05-15 | 2011-06-01 | 宁波科宁达工业有限公司 | Zwitterion analysis system of ion chromatographic instrument |
| CN103189119A (en) * | 2010-10-29 | 2013-07-03 | 赛默菲尼根有限责任公司 | Method and system for liquid chromatograph with compressibility and viscosity monitoring to identify fluids |
| CN103189119B (en) * | 2010-10-29 | 2015-05-27 | 赛默菲尼根有限责任公司 | Method and system for liquid chromatograph with compressibility and viscosity monitoring to identify fluids |
| CN106872623A (en) * | 2015-12-11 | 2017-06-20 | 中国科学院大连化学物理研究所 | A kind of two-dimensional gas chromatography interface |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| C19 | Lapse of patent right due to non-payment of the annual fee | ||
| CF01 | Termination of patent right due to non-payment of annual fee |