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CN212730744U - Improved anti-migration radioactive particles - Google Patents

Improved anti-migration radioactive particles Download PDF

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Publication number
CN212730744U
CN212730744U CN202020646664.6U CN202020646664U CN212730744U CN 212730744 U CN212730744 U CN 212730744U CN 202020646664 U CN202020646664 U CN 202020646664U CN 212730744 U CN212730744 U CN 212730744U
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CN
China
Prior art keywords
wedge
shaped
shell
radioactive
anchoring piece
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Active
Application number
CN202020646664.6U
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Chinese (zh)
Inventor
曹振
张俊
沈九零
魏永长
谢丛华
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Zhongnan Hospital of Wuhan University
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Zhongnan Hospital of Wuhan University
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Priority to CN202020646664.6U priority Critical patent/CN212730744U/en
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  • Medicinal Preparation (AREA)

Abstract

The utility model relates to an improved anti-moving radioactive particle, which comprises a shell and a radioactive source sealed in the shell, wherein a wedge-shaped groove is obliquely and downwards cut on the outer surface of the shell, and a wedge-shaped anchoring part is formed above the wedge-shaped groove; one end of the wedge-shaped anchoring piece is a connecting end integrally connected with the shell, and the other end of the wedge-shaped anchoring piece is a suspended free end; from the connecting end to the free end, both the width and the thickness of the wedge-shaped anchor are gradually reduced. When the wedge-shaped anchoring piece is used, the wedge-shaped anchoring piece is implanted into tumor tissue, and the free end of the wedge-shaped anchoring piece is inserted into the tumor tissue, so that radioactive particles are fixed in the tumor tissue, and the movement and the falling of the radioactive particles are avoided. Although the wedge-shaped anchoring piece is cut on the outer surface of the particle shell, the appearance of the particles is not damaged, so that the matching of the radioactive particles and the particle injection gun is not influenced; the biodegradable layer does not need to be coated outside the shell, so that the increase of the frictional resistance between the particles and the particle injection gun is not caused. In addition, the wedge-shaped structure of the anchoring piece reduces the hidden trouble that the anchoring piece falls off.

Description

Improved anti-migration radioactive particles
Technical Field
The utility model relates to a radioactive particle for treating tumor, in particular to an improved anti-moving radioactive particle.
Background
The implantation of particles, all known as "radioactive particle implantation therapy", is a therapeutic method in which a radioactive source is implanted inside a tumor and continuously emits radiation to destroy the tumor. The seed implantation treatment technology relates to a radioactive source, and the core of the seed implantation treatment technology is a radioactive seed. A substance known as iodine 125 is now in clinical use. Each iodine 125 particle acts like a small sun with the strongest rays near its center, minimizing damage to normal tissues. The particle implantation is widely applied to oncology, surgery, internal medicine, ophthalmology, gynecology and the like, and becomes one of effective methods for treating solid tumors. Compared with external irradiation, the method has low cost and simple equipment, thereby having wide application in clinic. However, the particles implanted in the tumor tissue are often shifted in position due to muscle movement, resulting in the change of the dose distribution, which not only results in the insufficient dose at the target area of the tumor, but also results in the excessive dose of the normal tissue. Moreover, some radioactive seeds implanted in the body automatically creep out of the body due to muscle movement before the radioactivity activity is completely lost, thereby causing radioactive pollution to the environment.
Chinese utility model patent No. CN 207085069U discloses a radioactive particle capable of fixing position by itself, wherein a plurality of elastic legs are provided on the outer surface of the shell of the radioactive particle, one end of each elastic leg is fixed on the shell, and the other end is a free end; the shell is externally coated with a biodegradable layer so as to apply external force to the elastic supporting leg to press the free end of the elastic supporting leg to the shell; when the external force exerted on the elastic supporting leg is eliminated, the free end of the elastic supporting leg is bounced. When in use, the radioactive particles are implanted into tumor tissues, and the biodegradable layer is gradually degraded. When the biodegradable layer is completely degraded, the elastic legs are bounced and opened, and the free ends of the elastic legs are inserted into tumor tissues, so that the radioactive particles are fixed, and the movement and falling off of the radioactive particles are avoided. Because the shell of the particle is wrapped by the biodegradable film, when the particle is loaded in the particle injection gun for injection, the existence of the biodegradable film can increase the friction resistance of the particle and the gun barrel. And the elastic legs also have the potential to fall off the particles.
Disclosure of Invention
In view of the problems identified in the background, the present invention provides an improved anti-migration radioactive seed.
The utility model discloses a movement-proof radioactive particle, which comprises a shell and a radioactive source sealed in the shell, wherein a wedge-shaped groove is obliquely and downwards cut on the outer surface of the shell, and a wedge-shaped anchoring part is formed above the wedge-shaped groove; one end of the wedge-shaped anchoring piece is a connecting end integrally connected with the shell, and the other end of the wedge-shaped anchoring piece is a suspended free end; from the connecting end to the free end, both the width and the thickness of the wedge-shaped anchor are gradually reduced.
Preferably, two symmetrical wedge-shaped anchoring parts are arranged at two ends of the outer surface of the shell.
Preferably, a plurality of groups of wedge-shaped anchoring pieces are arranged on the outer surface of the shell, and one group of wedge-shaped anchoring pieces are two symmetrical wedge-shaped anchoring pieces which are respectively arranged at two ends of the outer surface of the shell.
Preferably, the free end of the wedge-shaped anchor is pointed.
During the use, will the utility model discloses in the radioactive particle implantation tumor tissue, the tumor tissue is inserted to wedge anchor assembly's free end to make in the radioactive particle is fixed in tumor tissue, avoid its removal and drop.
Compared with the prior art, the utility model has the advantages of as follows and beneficial effect:
(1) although the wedge-shaped anchoring piece is cut on the outer surface of the particle shell, the appearance of the particles is not damaged, so that the matching of the radioactive particles and the particle injection gun is not influenced; the biodegradable layer does not need to be coated outside the shell, so that the increase of the frictional resistance between the particles and the particle injection gun is not caused.
(2) The wedge-shaped structure of the anchoring piece enables the possibility that the anchoring piece falls off from the radioactive particles to be extremely low, reduces the hidden danger that the anchoring piece falls off, and improves the safety of the use of the particles.
(3) The device has the advantages of low cost, simple structure, easy processing and suitability for industrialization.
Drawings
FIG. 1 is a perspective view of an active particle in the example;
FIG. 2 is a front view of the radioactive seeds in the example;
FIG. 3 is a side view of the radioactive seeds in the examples.
In the figure, 1-radioactive source, 2-shell, 3-wedge-shaped groove, 4-wedge-shaped anchoring piece and 4 a-free end.
Detailed Description
The following will explain in detail embodiments of the radioactive particles of the present invention with reference to the accompanying drawings.
Referring to fig. 1 to 3, it should be noted that the dotted lines in fig. 1 to 3 all represent the projection positions of the radiation sources. The radioactive particles of the present embodiment include a radioactive source 1 and a housing 2, and the radioactive source 1 is sealed in the housing 2. The housing 2 is made of titanium alloy, the radioactive source 1 is wrapped in powder or small particles in the titanium alloy housing for generating radiation, and the radioactive source can be iodine 125, palladium 103, iridium 192, etc., but is not limited thereto.
In order to stably fix the radioactive seeds in the tumor tissue, an anchor is provided on the outer surface of the housing 2. The wedge-shaped groove 3 is obliquely and downwardly cut on the outer surface of the shell 2, and the bottom surface of the wedge-shaped groove 3 is obliquely and downwardly arranged. A wedge-shaped anchoring piece 4 is formed above the wedge-shaped groove 3, one end of the wedge-shaped anchoring piece 4 is a connecting end integrally connected with the shell 2, and the other end is a suspended free end 4 a. The wedge-shaped anchor 4 has a width and a thickness that decrease from the connecting end towards the free end 4 a.
Preferably, two symmetrical wedge-shaped anchors are respectively arranged at two ends of the outer surface of the shell 2, and the two symmetrical wedge-shaped anchors are marked as a group of anchors. In order to further enhance the anchoring effect, a plurality of groups of anchoring elements can be arranged on the surface of the shell 2. In the embodiment, two groups of anchoring parts are arranged, as shown in fig. 1 to 3, only one of the anchoring parts is marked, and the structures and the sizes of all wedge-shaped anchoring parts are consistent.
When the radioactive seeds are implanted in the tumour tissue, the narrow free end 4a of the wedge-shaped anchor 4 is inserted into the tumour tissue, thus avoiding the migration and the shedding of the seeds. To obtain a more stable fixing effect, the free end 4a may be cut to a tip.
The utility model discloses in, the wedge groove 3 as long as satisfy the bottom along the decurrent condition of cutting direction slope can, the degree of depth of wedge groove 3 increases progressively along the cutting direction promptly, though the width of wedge groove 3 also increases progressively along with the cutting direction in this embodiment, nevertheless the utility model discloses do not require the change of 3 widths in wedge groove.
The utility model discloses radioactive particle, though cut out anchor assembly at its casing surface, nevertheless do not destroy radioactive particle's outward appearance, so can not influence the matching of radioactive particle and particle injection rifle, can not arouse frictional resistance's increase yet. Moreover, the anchoring piece is simple to process; in addition, due to the wedge-shaped structure of the anchor, the possibility of the anchor falling off from the radioactive particles is extremely low.

Claims (4)

1. Improved anti-moving radioactive particles comprise a shell and a radioactive source sealed in the shell, and are characterized in that:
a wedge-shaped groove is obliquely and downwards cut on the outer surface of the shell, and a wedge-shaped anchoring piece is formed above the wedge-shaped groove;
one end of the wedge-shaped anchoring piece is a connecting end integrally connected with the shell, and the other end of the wedge-shaped anchoring piece is a suspended free end;
from the connecting end to the free end, both the width and the thickness of the wedge-shaped anchor are gradually reduced.
2. The improved anti-migration radioactive seeds of claim 1, wherein:
two symmetrical wedge-shaped anchoring parts are arranged at two ends of the outer surface of the shell.
3. The improved anti-migration radioactive seeds of claim 1, wherein:
the outer surface of the shell is provided with a plurality of groups of wedge-shaped anchoring parts, and the group of wedge-shaped anchoring parts refer to two symmetrical wedge-shaped anchoring parts which are respectively arranged at two ends of the outer surface of the shell.
4. The improved anti-migration radioactive seeds of claim 1, wherein:
the free end of the wedge-shaped anchor is pointed.
CN202020646664.6U 2020-04-26 2020-04-26 Improved anti-migration radioactive particles Active CN212730744U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202020646664.6U CN212730744U (en) 2020-04-26 2020-04-26 Improved anti-migration radioactive particles

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202020646664.6U CN212730744U (en) 2020-04-26 2020-04-26 Improved anti-migration radioactive particles

Publications (1)

Publication Number Publication Date
CN212730744U true CN212730744U (en) 2021-03-19

Family

ID=75003130

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202020646664.6U Active CN212730744U (en) 2020-04-26 2020-04-26 Improved anti-migration radioactive particles

Country Status (1)

Country Link
CN (1) CN212730744U (en)

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