CN211934431U - Model of degradable zinc alloy pipe and mineralized collagen composite bone defect restoration - Google Patents
Model of degradable zinc alloy pipe and mineralized collagen composite bone defect restoration Download PDFInfo
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- CN211934431U CN211934431U CN201920995341.5U CN201920995341U CN211934431U CN 211934431 U CN211934431 U CN 211934431U CN 201920995341 U CN201920995341 U CN 201920995341U CN 211934431 U CN211934431 U CN 211934431U
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Abstract
The utility model discloses a model of compound bone defect restoration body of degradable zinc alloy pipe and mineralized collagen, including mould body, degradable zinc alloy pipe and mineralized collagen, the mould body with degradable zinc alloy pipe is the cylinder body, and the degradable zinc alloy pipe of cylinder body sets up in the mould body of cylinder body, and mineralized collagen is full of the cylinder body degradable zinc alloy pipe that has the distribution and arranges the hole and have micro arc oxidation coating inside and outside and inside, and freeze-drying shaping a model of compound bone defect restoration body of degradable zinc alloy pipe and mineralized collagen, simple structure, dependable performance, it is convenient to use. Aiming at the current clinical medical development trend, the model of the degradable zinc alloy pipe and mineralized collagen composite bone defect restoration combines the degradable zinc alloy pipe and mineralized collagen, and has wide application prospect.
Description
Technical Field
The utility model relates to the technical field of medical equipment design and production, concretely relates to a model design that is used for human bone defect to restore and rebuild the prosthesis that uses, especially relates to a model of degradable zinc alloy pipe and mineralize mineralization collagen composite bone defect prosthesis.
Background
Chinese utility model patent with publication number CN106388977A provides a defective bone restoration of facial bone, it includes bearing structure, osteogenesis structure and staple, bearing structure includes the structure roof beam, be provided with a plurality of fixed orifices along length direction on the structure roof beam, staple and fixed orifices swing joint, osteogenesis structure includes connecting hole and drainage hole, the connecting hole is located the upper end in drainage hole, bearing structure passes through connecting hole swing joint with osteogenesis structure, the type of free choice bearing structure and osteogenesis structure, size and matched stack mode, it is convenient to have the matched stack, conveniently cut out advantages such as, carry out the plasticity to bearing structure in the operation, then can carry out defective department with different osteogenesis structure and implant on installing bearing structure.
Bone repair materials, especially bone defect repair materials for large-section load-bearing parts, require materials with good mechanical properties, and traditional bone defect repair materials mainly comprise natural biological materials and artificial synthetic materials. The natural biological material is derived from autogenous bone, allogeneic bone and xenogeneic bone, and is only used for repairing small-volume defects due to the defects of limited material selection, immunological rejection reaction, infection risk and the like. For a part of bone defect with larger volume or needing to be weighed, the clinically adopted implant material with filling function, such as nano hydroxyapatite, mineralized collagen, polylactic acid, polyglycolic acid, lactic acid-glycolic acid copolymer, calcium phosphate, calcium sulfate, bioglass and the like, is characterized by light weight, good biocompatibility, easy molding and convenient postoperative examination, the size and character of the defect are not limited when being selected, but are crisp, the strength and toughness of the defect are limited, and the mechanical properties of tensile strength, compression strength and bending resistance of the bone defect can not achieve satisfactory effect; the bone fracture repairing material has the advantages that structural materials with repairing functions, such as titanium alloy plates, stainless steel meshes and zinc alloy bone nail bone plates, have excellent mechanical properties, but stress shielding can be generated due to large difference with the mechanical properties of autogenous bones, and the bone defect repairing and regeneration can not be completely realized due to direct contact of metal and tissues. Therefore, a material which has mechanical properties close to those of autogenous bone, has excellent biocompatibility and is used for large-size load-bearing bone defect repair and function reconstruction is urgently needed clinically. The degradable zinc alloy is protected by using the degradable metal as a mechanical support and fully utilizing the osteogenesis characteristic of mineralized collagen.
SUMMERY OF THE UTILITY MODEL
To the above-mentioned technical defect problem that exists among the prior art, in order to obtain above-mentioned anticipated degradable zinc alloy pipe and mineralized collagen complex bone defect restoration, the utility model provides a complex preparation model design that both can two kinds of completely different materials of full play the performance advantage separately, prepare moreover simply, convenient to use: a model of degradable zinc alloy pipe and mineralized collagen composite bone defect restoration.
In order to achieve the above purpose, the present invention adopts the following technical solution.
The model of the degradable zinc alloy tube and mineralized collagen composite bone defect restoration comprises a mould body, the degradable zinc alloy tube and mineralized collagen; the mould body with the degradable zinc alloy pipe is the cylinder body, and the degradable zinc alloy pipe of cylinder body sets up in the mould of cylinder body originally internally.
Preferably, the diameter of the degradable zinc alloy pipe of the cylindrical pipe body is smaller than that of the die body of the cylindrical pipe body.
In any of the above technical solutions, preferably, the degradable zinc alloy pipe of the cylindrical pipe body is fixed in the die body of the cylindrical pipe body, and the axes of the degradable zinc alloy pipe and the die body correspond to each other.
In any of the above technical solutions, preferably, the inner and outer surfaces of the degradable zinc alloy pipe of the cylindrical pipe body are both provided with micro-arc oxidation coatings.
In any of the above technical solutions, preferably, the degradable zinc alloy tube of the cylindrical tube body has holes distributed on the tube wall.
In any of the above technical solutions, preferably, the diameter range of the holes distributed and arranged on the tube wall of the degradable zinc alloy tube with the cylindrical tube body is 0.2 mm-2 mm.
In any of the above technical solutions, preferably, the mineralized collagen is filled inside and outside the cylindrical tube degradable zinc alloy tube with the distribution holes and the micro-arc oxidation coating inside and outside, and a model of the degradable zinc alloy tube and mineralized collagen composite bone defect restoration is formed by freeze drying.
In any of the above technical solutions, it is preferable that the cylindrical tube body degradable zinc alloy tube fixed in the cylindrical tube body mold body is injected with mineralized collagen, the mineralized collagen is extruded out of the tube through the distribution holes on the tube wall, and fills the gap between the outer wall of the degradable zinc alloy tube and the mold body, so as to form a solid cylindrical model of the degradable zinc alloy tube and mineralized collagen composite bone defect prosthesis.
In any of the above solutions, it is preferable that the solid cylinder model has a diameter of 10 mm.
In any of the above solutions, it is preferable that the solid cylinder model is mass-produced or personalized and customized according to the bone defect repair site.
Compared with the prior art, the above technical scheme of the utility model following beneficial effect has:
the application of mineralized collagen in bone defect repair is commercialized, and a plurality of related products imported and made in China in the market are widely used in medicine. Degradable metals have attracted much attention as biomedical materials newly developed in recent years, and related medical devices are gradually developed. But the application of combining the two is less involved in hunting and in the initial stage of research, and has wide application prospect.
The utility model discloses technical scheme the mould body adopts the mould body preparation that is applicable to degradable material, jointly mineralizes the collagen material with degradable zinc alloy and is used for preparing the bone defect restoration body, and the performance advantage of two kinds of materials of full play both can provide good mechanics supporting role in bone repair process, can reach the degradation and the bone repair regeneration process phase-match of material again, promotes the regeneration of restoration of bone tissue, provides the theoretical foundation for the research and development of novel biological bone grafting material and the joint application of different grade type bone grafting material.
Is right according to the shape of the bone defect of the patient the utility model discloses repair and carry out the secondary moulding in the temperature range that different materials are suitable for, solved the difficult problem of revising behind the plasticity. The doctor can use the device conveniently, thereby saving the operation time and reducing the pain of the patient and the medical cost.
Drawings
In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings needed to be used in the description of the embodiments or the prior art will be briefly described below, it is obvious that the drawings in the following description are only some embodiments of the present invention, and for those skilled in the art, other drawings can be obtained according to these drawings without inventive exercise.
Fig. 1 is a schematic view of a preferred embodiment of a model structure of a degradable zinc alloy tube and mineralized collagen composite bone defect prosthesis according to the present invention;
FIG. 2 is a schematic view of a preferred embodiment of a degradable zinc alloy tube structure of a model of a degradable zinc alloy tube and mineralized collagen composite bone defect prosthesis according to the present invention;
FIG. 3 is a schematic view of a preferred embodiment of a model profile structure of a degradable zinc alloy tube and mineralized collagen composite bone defect prosthesis according to the present invention;
reference numerals:
1. the mold comprises a mold body, 2, a degradable zinc alloy pipe, 3, mineralized collagen, 4, an axis, 5, zinc-calcium-strontium alloy, 6 and a coating.
Detailed Description
The technical solutions in the embodiments of the present invention will be described clearly and completely with reference to the accompanying drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only some embodiments of the present invention, not all embodiments. Based on the embodiments in the present invention, all other embodiments obtained by a person skilled in the art without creative work belong to the protection scope of the present invention.
In order to overcome the problems of the preparation of the bone defect restoration in the prior art, the embodiment of the utility model provides a model of the degradable zinc alloy tube and mineralized collagen composite bone defect restoration, which can not only give full play to the respective performance advantages of two completely different materials, but also has simple preparation and convenient use for preparing the model design of the composite body preparation, and can obtain the expected degradable zinc alloy tube and mineralized collagen composite bone defect restoration by using the model.
As shown in fig. 1, the model of the degradable zinc alloy tube and mineralized collagen composite bone defect prosthesis of the embodiment includes a mold body, a degradable zinc alloy tube and mineralized collagen; the mould body with the degradable zinc alloy pipe is the cylinder body, and the degradable zinc alloy pipe of cylinder body sets up in the mould of cylinder body originally internally.
In the model of the degradable zinc alloy tube and mineralized collagen composite bone defect restoration, the diameter of the degradable zinc alloy tube of the cylindrical tube body is smaller than that of the mold body of the cylindrical tube body.
In the model of the degradable zinc alloy tube and the mineralized collagen composite bone defect restoration, the degradable zinc alloy tube of the cylindrical tube body is fixed in the mold body of the cylindrical tube body, and the axes of the degradable zinc alloy tube and the mold body correspond to each other.
In the model of the degradable zinc alloy tube and mineralized collagen composite bone defect restoration, the inner surface and the outer surface of the degradable zinc alloy tube of the cylindrical tube body are both provided with micro-arc oxidation coatings.
In the model of the degradable zinc alloy tube and mineralized collagen composite bone defect restoration, the tube wall of the degradable zinc alloy tube of the cylindrical tube body is provided with the distribution holes.
In the model of the degradable zinc alloy tube and mineralized collagen composite bone defect restoration, the diameter range of the holes distributed and arranged on the tube wall of the degradable zinc alloy tube of the cylindrical tube body is 0.2 mm-2 mm.
In the model of the degradable zinc alloy tube and the mineralized collagen composite bone defect restoration, mineralized collagen is filled inside and outside the degradable zinc alloy tube with the cylindrical tube body which is provided with the distribution holes and the micro-arc oxidation coating inside and outside, and the model of the degradable zinc alloy tube and the mineralized collagen composite bone defect restoration is formed by freeze drying.
The model of the degradable zinc alloy tube and mineralized collagen composite bone defect restoration is a cylindrical tube degradable zinc alloy tube fixed in a cylindrical tube mould body, mineralized collagen is injected into the degradable zinc alloy tube, and the mineralized collagen is extruded out of the tube through distribution holes on the tube wall to fill a gap between the outer wall of the degradable zinc alloy tube and the mould body, so that the model of the degradable zinc alloy tube and mineralized collagen composite bone defect restoration with a solid cylinder is formed.
In the model of the degradable zinc alloy tube and mineralized collagen composite bone defect prosthesis, the diameter of the solid cylinder model is 10 mm.
In the model of the degradable zinc alloy tube and mineralized collagen composite bone defect restoration, the solid cylinder model is prepared in batch or customized according to the bone defect restoration position.
The model of the degradable zinc alloy tube and mineralized collagen composite bone defect restoration provided by the embodiment has the advantages that the degradable zinc alloy tube and mineralized collagen are effectively compounded to form a tubular structure, the degradable zinc alloy tube is punched to degrade a micro-arc oxidation coating on the surface of the zinc alloy, the composite body is fixed by using a mold, the inside and the outside of the tube are filled with mineralized collagen, and the model is formed in a freeze drying mode. The prosthesis model can be changed in size according to the repair part, and is prepared in batches or customized personally according to the bone defect repair position. The utility model discloses simple structure, the dependable performance, it is convenient to use, jointly mineralizes collagen material with degradable zinc alloy and is used for preparing the bone defect restoration, and the performance advantage of two kinds of materials of full play both can provide good mechanics supporting role in bone repair process, can reach the degradation and the bone repair regeneration process phase-match of material again, promotes the regeneration of restoration of bone tissue, reduces patient's misery and treatment cost.
Fig. 2 and 3 are schematic diagrams of the porous zinc alloy tube/mineralized collagen composite, wherein fig. 3 shows a cross-sectional structure. The principles and features of the present embodiment are further described below in conjunction with fig. 1-3.
The model of the degradable zinc alloy tube and mineralized collagen composite bone defect restoration is formed into a similar cylindrical model design structure by filling mineralized collagen inside and outside the zinc tube with the perforated degradable zinc alloy surface micro-arc oxidation coating. The whole model is a cylinder structure model, and the surface of the degradable zinc alloy pipe is provided with a micro-arc oxidation coating. Holes are distributed on the pipe wall of the degradable zinc alloy pipe, the diameter range of the holes is 0.2-2 mm, mineralized collagen liquid solution (similar to plasticine) is injected into the pipe, the degradable zinc alloy pipe is filled with the mineralized collagen liquid solution after the liquid solution is extruded from the hole of the degradable zinc alloy pipe, and the injection can be stopped. Mineralized collagen is filled between the degradable zinc alloy pipe and the mould body. The model of the degradable zinc alloy tube and mineralized collagen composite bone defect prosthesis of the embodiment is a solid cylinder with the diameter of 10mm, and the obvious layered structure can be seen from the sectional view of fig. 3. The composite model can be prepared in batch, and can also be customized according to individual requirements. The bone defect prosthesis models at different positions can be prepared, and the preparation process comprises the following steps: preparing a composite die for later use; preparing a degradable zinc alloy pipe and punching; fixing the degradable zinc alloy pipe in a mould body, firstly injecting mineralized collagen liquid solution (a substance similar to plasticine) into the degradable zinc alloy pipe, and stopping injection when the liquid solution is extruded from the degradable zinc alloy pipe hole and is full of the degradable zinc alloy pipe; continuously adding the mineralized collagen in the form of solution of injection liquid between the degradable zinc alloy pipe and the mould body until the gap between the mould body and the outer wall of the degradable zinc alloy pipe is completely filled; freeze-drying the model of the degradable zinc alloy tube and the mineralized collagen composite bone defect restoration; and taking out the degradable zinc alloy pipe and the mineralized collagen complex for later use.
The model of the embodiment can be used for obtaining the expected degradable zinc alloy tube and mineralized collagen composite bone defect restoration, the embodiment is a composite body preparation model design which gives full play to respective performance advantages of two completely different materials, is simple to prepare and convenient to use, can provide a good mechanical supporting effect in the bone repairing process, can achieve the matching of the degradation of the materials and the bone repairing and regenerating process, and promotes the repairing and regenerating of bone tissues. The model is characterized in that the tubular structure is similar to a solid cylinder, the degradable zinc tube part of the solid cylinder is provided with through holes and is filled with mineralized collagen, and the section of the solid cylinder is obviously layered. Compared with the prior art, the embodiment has the following outstanding beneficial effects:
1. the application of mineralized collagen in bone defect repair is commercialized, and a plurality of related products imported and made in China in the market are widely used in medicine. Degradable metals have attracted much attention as biomedical materials newly developed in recent years, and related medical devices are gradually developed. But the application of combining the two is less involved in hunting and in the initial stage of research, and has wide application prospect.
2. The preparation mold is suitable for degradable materials, the degradable zinc alloy combined mineralized collagen material is used for preparing the bone defect restoration body, the performance advantages of the two materials are fully exerted, a good mechanical supporting effect can be provided in the bone restoration process, the degradation of the materials can be matched with the bone restoration and regeneration process, the restoration and regeneration of bone tissues are promoted, and a theoretical basis is provided for the research and development of novel biological bone grafting materials and the combined application of different types of bone grafting materials.
3. Is right according to the shape of the bone defect of the patient the utility model discloses repair and carry out the secondary moulding in the temperature range that different materials are suitable for, solved the difficult problem of revising behind the plasticity. The doctor can use the device conveniently, thereby saving the operation time and reducing the pain of the patient and the medical cost.
The above description is only intended to describe the preferred embodiments of the present invention, and not to limit the scope of the present invention; the above description is only a specific embodiment of the present invention, and is not intended to limit the scope of the present invention; without departing from the spirit of the present invention, any modification, equivalent replacement, or improvement made by the technical solution of the present invention by those of ordinary skill in the art should fall within the protection scope defined by the claims of the present invention.
Claims (10)
1. A model of a degradable zinc alloy tube and mineralized collagen composite bone defect restoration comprises a mould body, a degradable zinc alloy tube and mineralized collagen, and is characterized in that: the mould body with the degradable zinc alloy pipe is the cylinder body, and the degradable zinc alloy pipe of cylinder body sets up in the mould of cylinder body originally internally.
2. The model of the degradable zinc alloy tube and mineralized collagen composite bone defect prosthesis according to claim 1, wherein: the diameter of the degradable zinc alloy pipe of the cylindrical pipe body is smaller than that of the mold body of the cylindrical pipe body.
3. The model of the degradable zinc alloy tube and mineralized collagen composite bone defect prosthesis according to claim 1, wherein: the degradable zinc alloy pipe of the cylindrical pipe body is fixed in the mould body of the cylindrical pipe body, and the axes of the degradable zinc alloy pipe and the mould body correspond.
4. The model of the degradable zinc alloy tube and mineralized collagen composite bone defect prosthesis according to claim 1, wherein: the inner surface and the outer surface of the degradable zinc alloy pipe of the cylindrical pipe body are both provided with micro-arc oxidation coatings.
5. The model of the degradable zinc alloy tube and mineralized collagen composite bone defect prosthesis according to claim 1, wherein: and the pipe wall of the degradable zinc alloy pipe of the cylindrical pipe body is provided with distribution holes.
6. The model of degradable zinc alloy tube and mineralized collagen composite bone defect restoration as set forth in claim 5, wherein: the diameter range of the holes distributed on the pipe wall of the degradable zinc alloy pipe of the cylindrical pipe body is 0.2 mm-2 mm.
7. The model of degradable zinc alloy tube and mineralized collagen composite bone defect prosthesis according to any one of claims 1 to 6, wherein: the mineralized collagen is filled inside and outside the degradable zinc alloy pipe with the cylindrical pipe body which is provided with the distribution holes and the micro-arc oxidation coating inside and outside, and a model of the degradable zinc alloy pipe and the mineralized collagen composite bone defect restoration body is formed by freeze drying.
8. The model of degradable zinc alloy tube and mineralized collagen composite bone defect prosthesis according to any one of claims 1 to 6, wherein: the degradable zinc alloy pipe is fixed in the cylindrical pipe body mould body, mineralized collagen is injected into the degradable zinc alloy pipe, the mineralized collagen is extruded out of the pipe through distribution holes on the pipe wall, and a gap between the outer wall of the degradable zinc alloy pipe and the mould body is filled, so that a model of a solid cylindrical degradable zinc alloy pipe and mineralized collagen composite bone defect restoration body is formed.
9. The model of degradable zinc alloy tube and mineralized collagen composite bone defect restoration as set forth in claim 8, wherein: the solid cylinder model has a diameter of 10 mm.
10. The model of degradable zinc alloy tube and mineralized collagen composite bone defect restoration as set forth in claim 8, wherein: the solid cylinder model is prepared in batches or customized according to the bone defect repair position.
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| CN201920995341.5U CN211934431U (en) | 2019-06-28 | 2019-06-28 | Model of degradable zinc alloy pipe and mineralized collagen composite bone defect restoration |
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| CN201920995341.5U CN211934431U (en) | 2019-06-28 | 2019-06-28 | Model of degradable zinc alloy pipe and mineralized collagen composite bone defect restoration |
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