CN217931701U - Multi-project body fluid analyzer - Google Patents

Abstract

The utility model discloses a multinomial mesh body fluid analysis appearance, the on-line screen storage device comprises a base, the base top is equipped with test-tube rack material loading module, a plurality of test tubes of test-tube rack inside installation side by side, test-tube rack movable mounting is to test-tube rack material loading module, test-tube rack module side is equipped with test-tube rack transport module, test-tube rack material loading module drive test-tube rack removes, and install its propelling movement to test-tube rack transport module, the base top is equipped with test paper strip partial shipment module and the concentrated module of cell centrifugation, test-tube rack transport module drives test tube in the test-tube rack corresponding with test paper strip partial shipment module in test paper strip partial shipment module, test paper strip detection module is located test paper strip partial shipment module top, the concentrated module outside of cell centrifugation is equipped with cell morphology scanning module, snatch the test-tube rack of transferring module on with test-tube rack transport module and snatch to the concentrated module of cell centrifugation in proper order, cell morphology scanning module. The instrument has a simple structure, adopts a liquid-free pipeline design, and can realize full-automatic detection of multiple specimens and multiple projects.

Description

Multi-project body fluid analyzer

Technical Field

The utility model relates to a medical treatment analytical instrument technical field, concretely relates to multinomial mesh body fluid analysis appearance.

Background

The analytical instrument and the main working flow adopted in the detection of urine, gynecological secretion (leucorrhea) and excrement in the current market are as follows:

a full-automatic urine production line (a production line consisting of 2 machines of a full-automatic urine dry chemical analyzer and a urinary sediment cell morphology analyzer): the urine dry chemical test paper utilizes a reflectivity principle, adopts a diode or an image sensor as a detection receiving device, and adopts a microscopic cell image recognition or flow cytometry principle for urinary sediment cell morphology. The main working flows of the 2 machine samples are as follows: the method comprises the steps of test tube rack feeding, needle suction and sample suction, silica gel pipeline conveying, pipeline cleaning, pipeline disinfection and the like. The chemical analyzer includes: the test strip selecting and feeding assembly, the needle tube liquid sucking and dropping assembly and the optical probe scanning assembly are arranged in the test strip box; the urinary sediment cell morphology analyzer comprises: liquid is pumped into a counting cell, scanned by a microscope or a flow cytometry probe, etc.

Gynecological secretion analysis system (comprising automatic vaginitis detection workstation (vaginitis joint test paper card), microscopic cell analyzer, etc.). The analysis method is similar to urine, but the sample treatment method is different, the cotton ball sample is sampled by adopting a cotton ball, diluted and washed, and then a glass slide is coated, the test paper is in a gold-labeled card type with a plastic plate, and the operation steps of sample suction by other suction needles, cleaning, liquid pipeline and the like are the same.

The sample processing method of the full-automatic excrement analyzer is similar to that of leucorrhea, a small spoon is used for sampling, a special excrement cup net is used for filtering and storing, a motor is used for stirring and mixing uniformly, and then a flowing counting cell or a disposable counting plate is used for photographing.

The above analytical instruments all have the following disadvantages when in use:

(1) A large number of complex liquid pipelines and liquid path controllers are adopted, and the problems of cross contamination, pipeline hole blockage, repeated washing after each sample adding, high cost, easy error and the like exist;

urine sediment cells, leucorrhea and excrement are high-viscosity samples, so that pipelines and a counting pool are easily blocked, cross contamination is easily caused, a large amount of waste liquid and reagent are easily consumed when disinfection pipelines and equipment are cleaned, the treatment process is time-consuming, particularly, urine sediment and the like need to be centrifuged to remove supernatant, the conventional layered sediment taking automatic instrument is difficult to realize, and meanwhile, the sample suction needle is difficult to suck due to high sediment viscosity, and the sample is difficult to convey to the flow counting pool through a silicone tube; in addition, the urinary sediment centrifugation cannot realize the effect of cell centrifugation concentration due to too great difficulty, and concentrated cells are not adopted, so that the detection positive rate is low, the detection is easy to miss, and the scanning pictures are many and time-consuming.

(2) The instrument uses each human specimen as a processing unit, and processes each specimen in a circulating way, thereby consuming time and labor, having slow specimen processing and detecting speed and having complex instrument structure.

(3) Urine, gynecological secretion, excrement and other samples are independent instruments, so that resource sharing among the instruments cannot be realized, and the development, production, after-sale maintenance and management costs are increased.

(4) The test strip partial shipment adopts the drum formula partial shipment mode, appears blocking easily, falls the strip phenomenon, and anti strip fault rate is high.

SUMMERY OF THE UTILITY MODEL

In order to solve the problem that exists among the above-mentioned background art, the utility model provides a multinomial project body fluid analysis appearance, it uses the test-tube rack as the operation unit to adopt no liquid pipeline design, only need remove test-tube rack to each detection module, can realize multiple sample and multinomial project in the full automated inspection of an organic whole, practiced thrift check-out time greatly, improved detection speed and detection precision, reduced the instrument complexity, this instrument operation is reliable and stable moreover.

In order to realize the purpose, the utility model adopts the following technical scheme:

the utility model provides a multi-project body fluid analyzer, which comprises a base, test tubes, a test tube rack feeding module, a test tube rack conveying module, a test strip split charging module, a test strip detection module, a cell centrifugal concentration module, a cell morphology scanning module and a grabbing and transferring module;

a plurality of test tubes are arranged in the test tube rack side by side,

the test tube rack feeding module is arranged at the top of the base, the test tube rack is movably mounted on the test tube rack feeding module, the test tube rack conveying module is arranged beside the test tube rack module, the test tube rack feeding module drives the test tube rack to move and pushes and mounts the test tube rack on the test tube rack conveying module,

the top of the base is provided with a test strip split charging module and a cell centrifugal concentration module along the conveying direction of the test tube rack conveying module,

the test tube rack conveying module drives the test tube rack to move and rotate, and controls test tubes in the test tube rack to correspond to test strips in the test strip sub-packaging module,

the test strip detection module is positioned on the base and above the test strip subpackaging module,

the cell morphology scanning module is arranged at the outer side of the cell centrifugal concentration module,

the grabbing and transferring module sequentially grabs the test tube racks on the test tube rack conveying module to the cell centrifugal concentration module and the cell morphology scanning module.

The improved test tube comprises a tube body, the tube body is of a hollow structure with two open ends, a cover plug is installed at the opening of one end of the tube body in a sliding and sealing mode, a liquid discharge tube is arranged at the opening of the other end of the tube body, a liquid discharge cap plug is arranged at the end of the liquid discharge tube in a covering mode, a liquid blocking plug is arranged inside the liquid discharge cap plug and is in movable sealing contact with the end of the liquid discharge tube, a liquid discharge hole is formed in the side face of the liquid discharge cap plug, the tube body is far away from an opening in the side face of one end of the cover plug to form a liquid guide groove, a cover body of a transparent structure is movably and hermetically installed at the position of the liquid guide groove, and an automatic separation assembly used for separating and covering the liquid discharge tube and the liquid blocking plug in the liquid discharge cap plug is arranged on the base.

The improved structure is characterized in that a liquid blocking part is arranged at the joint of the liquid guiding groove and the pipe body, a liquid flowing channel used for communicating the inside of the pipe body and the liquid guiding groove is arranged in the liquid blocking part, and the height of the liquid flowing channel close to the liquid guiding groove is lower than the height of the liquid flowing channel close to the pipe body.

The liquid baffle is characterized in that a filter screen slot is formed in the end part, close to the liquid guide slot, of the liquid baffle, and a filter screen is inserted into the filter screen slot.

The improved test tube rack is characterized in that the automatic separation assembly is fixedly installed on the test strip detection module through a fixing seat, the automatic separation assembly is located between the test tube rack conveying module and the test strip subpackaging module, the automatic separation assembly comprises a U-shaped installation part, a telescopic driving part, a sliding part, a connecting part, a first fixing plate, a pulling claw and a jacking column, the U-shaped installation part is fixedly installed at the bottom of the fixing seat, the sliding part is slidably installed inside the U-shaped installation part, the end part of the telescopic driving part is connected with one end of the sliding part to drive the sliding part to move back and forth inside the U-shaped installation part, the first fixing plate is connected with the sliding part through the connecting part, a plurality of jacking columns and pulling claws are installed on the first fixing plate, the jacking columns and the pulling claw are arranged in a staggered mode, the end part of the jacking columns can movably extend into the test tube rack, and correspond to the free end of a liquid drainage cap plug on the test tube, a plurality of insertion grooves are formed inside, and the insertion grooves can be movably inserted into the liquid drainage cap plug on the test tube.

The test tube rack is further improved in that the test tube rack conveying module comprises a first linear moving assembly, a sliding plate, a mounting seat, a rotating motor, a rotating rod, a connecting frame body, an oscillator, an electric heating thermostatic plate, a supporting plate and an elastic clamping fixing piece, wherein the first linear moving assembly is fixedly mounted at the top of the base, the first linear moving assembly is connected with the sliding plate located above the first linear moving assembly, the top of the sliding plate is symmetrically provided with two mounting seats, the two mounting seats are connected between the two mounting seats in a rotating mode, one end of the rotating rod is connected with the rotating motor in a driving mode, the connecting frame body is fixedly mounted on the rotating rod, the top end of the connecting frame body is sequentially connected with the oscillator and the electric heating thermostatic plate, the top end of the electric heating thermostatic plate is provided with the supporting plate used for placing the test tube rack, the elastic clamping fixing piece used for clamping fixing the outer side of the test tube rack is arranged on the supporting plate, the top end of the supporting plate is further provided with a liquid drainage pushing cylinder, the output end of the liquid drainage pushing cylinder is connected with a second fixing plate, a plurality of liquid drainage push rods are arranged on the second fixing plate side by side, and are in movable contact with a cap plug of the end portion of the test tube rack.

The test strip split charging module comprises a bottom plate, fixing columns, a table plate, a split charging manipulator, a second linear moving assembly, a mounting plate, a feeding plate, a test strip storage box and a test strip pushing cylinder, wherein the bottom plate is positioned on the base, the top of the bottom plate is fixedly provided with a plurality of fixing columns, the table plate and the mounting plate are fixedly mounted on the fixing columns respectively, a plurality of grooves for placing test strips are formed in the table plate side by side, the second linear moving assembly is positioned on the bottom plate and fixedly connected with the split charging manipulator positioned above the second linear moving assembly, the second linear moving assembly drives the split charging manipulator to move along the direction vertical to the length of the test strips in the grooves, a supporting groove is formed in the position, corresponding to the grooves, of the top of the split charging manipulator, and an opening for the split charging manipulator to pass through is formed in the table plate; the test paper strip feeding mechanism comprises a mounting plate, a feeding plate, a test paper strip storage box, a feeding plate and a feeding manipulator, wherein the feeding plate is movably arranged at the top of the mounting plate, a containing groove used for containing the test paper strip is formed in the top of the feeding plate, the length direction of the containing groove is consistent with the length direction of a groove in a platen, the test paper strip storage box is mounted on the mounting plate, the bottom of the test paper strip storage box is provided with an opening corresponding to the containing groove, the end part of the feeding plate is connected with the test paper strip pushing cylinder, the feeding plate moves towards or away from the platen and is located at the containing groove, and an opening for the split charging manipulator to pass through the feeding plate is formed in the containing groove.

The further improvement is that a third linear moving assembly is arranged on the top of the base and is in driving connection with the bottom plate, and the third linear moving assembly drives the bottom plate to move in the direction close to or far away from the test tube rack conveying module.

The improved structure is characterized in that one end, far away from the test tube rack conveying module, of the bottom plate is hinged to the top of the base, an electric push rod is hinged to the inside of the base, and the output end of the electric push rod penetrates through the base and is connected with the bottom of the bottom plate.

The cell centrifugal concentration module is further improved in that the cell centrifugal concentration module comprises a centrifugal container, the bottom of the centrifugal container is arranged on the base, a tray for fixedly mounting the test tube rack is arranged in the centrifugal container, a protective cover is arranged at an opening at the top of the centrifugal container in a movable mode, a centrifugal motor is arranged at the bottom of the centrifugal container, and a driving end of the centrifugal motor penetrates through the centrifugal container and is connected with the bottom of the tray;

the cell morphology scanning module includes the work platen, work platen below is equipped with the support, the support top is equipped with X axle moving module, X axle moving module is connected with the work platen bottom, the work platen top is equipped with Y axle moving module, be connected with the test-tube rack fixed plate on the Y axle moving module, test-tube rack fixed plate top is equipped with and is used for fixing spacing locating part to the test-tube rack, work platen top is equipped with high power objective and low power objective, the work platen side is equipped with the third fixed plate of vertical setting, be equipped with Z axle moving module on the third fixed plate, high power objective and low power objective outside are passed through the connecting seat and are linked to each other with Z axle moving module.

Compared with the prior art, the utility model discloses following beneficial effect has:

1. the instrument adopts a liquid-free pipeline, has simple structure and less faults, the existing instruments on the market all adopt a complex liquid pipeline consisting of a suction needle for sucking samples, a silica gel pipeline for conveying samples, dropping samples, a counting cell for filling samples, a flushing pipeline, a disinfection pipeline, an electromagnetic valve for controlling, a peristaltic pump and the like, the pipeline is complex to control, easy to block holes and cross contamination, high in fault and free of the liquid pipeline, and the instrument has the most outstanding advantages;

2. the instrument processes and detects a plurality of samples at one time by taking a plurality of test tube samples on the test tube rack as an operation unit, and can finish various detection items as long as the test tube rack is moved to each detection module, thereby greatly saving the detection time and reducing the complexity of the instrument;

3. each detection module of this instrument has simplified the instrument for the sharing of various specimens, practices thrift a large amount of costs, has realized that many samples multinomial detect as an organic whole: including urine, leucorrhea, stool and other body fluid samples; multiple chemical test paper and microscopic cell morphology multi-item detection;

4. the instrument is simplified: the instrument is simplified from the structure and principle, the work which can be completed by more than ten instruments of other companies in the market is simplified to one machine, and the instrument has the advantages of simple structure, low cost, more stability and reliability and extremely low failure rate;

5. the detection technology aspect is as follows: the test strip detection module adopts a mode of combining a CCD camera with a large-area light source and computer image analysis software innovatively, can detect a plurality of test strips and a plurality of samples simultaneously, greatly improves the analysis accuracy and improves the detection speed by dozens of times compared with the mode that a diode, an image sensor and a lower microcomputer chip are used as detection devices in the market;

6. the structure of the test tube in the instrument is improved, and all processes of sample taking, loading, mixing, filtering, centrifuging, liquid discharging and microscopic examination are completed in a sealed test tube cavity;

7. the cell morphology scanning module adopts a large object carrying platform and a fixed double-objective full-automatic microscope, the object carrying platform can be arranged in a test tube rack with 5-10 test tubes, the high-power objective and the low-power objective do not need to be switched, and the double-objective works simultaneously;

8. the test strip split charging module adopts a box-type cartridge clip to horizontally push and feed in the test strip feeding process, so that the phenomena of time consumption, askew running, reverse running, strip clamping, strip falling and the like of the test strip in the process of taking materials by adopting roller-type feeding in the market are avoided;

9. the cell centrifugal concentration module adopts unique frame type centrifugation, and a test tube rack provided with a plurality of test tubes is automatically placed in a centrifugal container through the grabbing and transferring module at one time without inserting one test tube into the centrifugal container;

10. full automation: all items of all specimens are automatic, an operator only needs to put test tubes with sample liquid into a test tube rack, the test tube rack is installed on a test tube rack feeding module, test strip storage boxes with 50-100 chemical test strips are loaded into a test strip subpackaging module, and other items are completed by an instrument in a full-automatic mode: automatic feeding, mixing, dropping liquid, constant temperature, test strip detection, centrifugation, microscopic cell morphology detection, waste material abandoning, realize unmanned on duty full automatization.

11. The instrument is a full-automatic instrument, and can be suitable for large 3A hospitals and small hospitals; urine, leucorrhea and excrement are 3 conventional items in hospitals, so the demand is particularly large; in addition, the instrument has a simple structure, all sample modules are shared, and the production cost is extremely low; and the instrument has the advantages of less stable faults, high detection speed and wide market prospect.

Drawings

The present invention will be described in further detail with reference to the accompanying drawings and specific embodiments.

FIG. 1 is a schematic view of the overall structure of a multi-item body fluid analyzer according to the present invention;

FIG. 2 is a schematic view of the structure of the test tube of the present invention;

FIG. 3 is a schematic view of the split structure of the test tube of the present invention;

FIG. 4 is a schematic structural view of the test tube and the test tube rack of the present invention when they are installed in a matching manner;

fig. 5 is a schematic structural diagram of a feeding module of the pilot scale rack of the present invention;

fig. 6 is a schematic structural view of the pilot scale rack conveying module of the present invention;

fig. 7 is a schematic view of a partial structure of the sliding plate according to the present invention;

fig. 8 is a schematic structural view of the pilot test paper strip split charging module of the present invention;

FIG. 9 is a schematic view of a partial structure of the feeding plate of the present invention;

fig. 10 is a schematic view of a partial structure of a pilot test paper strip detection module according to the present invention;

fig. 11 is a schematic structural view of the automatic separating assembly of the present invention;

FIG. 12 is a schematic structural view of a centrifugal cell concentrating module according to the present invention;

FIG. 13 is an enlarged view of the structure at A in FIG. 1;

wherein the specific reference numerals are: a base 1, a waste disposal port 2, a test tube 3, a tube body 301, a cover plug 302, a connecting column 303, a sampler 304, a liquid guiding groove 305, a cover body 306, a liquid blocking member 307, a filter screen slot 308, a filter screen 309, a liquid discharging pipe 310, a positioning boss 311, a liquid discharging cap plug 312, a liquid discharging hole 313, a test tube rack 4, a test tube rack feeding module 5, a linear driving assembly 501, a material rack 502, a guide rail 503, a feeding guide groove 504, a test tube rack pusher 505, a test tube rack conveying module 6, a first linear moving assembly 601, a sliding plate 602, a mounting seat 603, a rotating motor 604, a rotating rod 605, a connecting frame body 606, an oscillator 607, an electrothermal constant temperature plate 608, a supporting plate 609, an elastic clamping fixing member 610, a liquid discharging pushing cylinder 611, a second fixing plate 612, a liquid discharging push rod 613, a test strip sub-packaging module 7, a bottom plate 701, a fixing column 702, a platform plate 703, a groove 704, a sub-packaging manipulator and a supporting groove 706, a second linear moving assembly 707, a mounting plate 708, a guide bar 709, a feeding plate 710, a receiving groove 711, a test strip storage box 712, a test strip pushing cylinder 713, a third linear moving assembly 714, a test strip detection module 8, a support frame 801, a ccd detection device 802, an automatic separation assembly 9, a fixed seat 901, a u-shaped mounting member 902, a telescopic driving member 903, a sliding member 904, a connecting member 905, a first fixed plate 906, a pulling claw 907, a tightening column 908, a cytocentrifugal concentration module 10, a centrifugal container 1001, a tray 1002, a protective cover 1003, a sliding rail 1004, a protective cover pushing cylinder 1005, a cytomorphological scanning module 11, a workbench plate 1101, a support 1102, an x-axis moving module 1103, a y-axis moving module 1104, a test tube rack fixed plate 1105, a high power objective 1106, a low power objective 1107, a third fixed plate 1108, a z-axis moving module 1109, and a grasping and transferring module 12.

Detailed Description

The embodiment of the utility model discloses a multi-project body fluid analyzer, as shown in fig. 1 and 4, comprising a base 1, a test tube 3, a test tube rack 4, a test tube rack feeding module 5, a test tube rack conveying module 6, a test strip subpackaging module 7, a test strip detecting module 8, a cell centrifugal concentration module 10, a cell morphology scanning module 11 and a grabbing and transferring module 12;

inside a plurality of test tubes 3 of installing side by side of test-tube rack 4, 1 top of base is equipped with test-tube rack feeding module 5, 4 movable mounting of test-tube rack to test-tube rack feeding module 5, 4 module sides of test-tube rack are equipped with test-tube rack transport module 6, test-tube rack feeding module 5 drive test-tube rack 4 removes, and with test-tube rack 4 propelling movement installation to test-tube rack transport module 6 on, 1 top of base is equipped with test paper strip partial shipment module 7 and the concentrated module 10 of cell centrifugation along test-tube rack transport module 6's direction of transfer, test-tube rack transport module 6 drives test-tube rack 4 and removes and rotates, and test tube 3 in the control test-tube rack 4 is corresponding with the test paper strip in the test paper strip partial shipment module 7, test paper strip detection module 8 is located base 1, and be located test paper strip partial shipment module 7 top, the concentrated module 10 outside of cell centrifugation is equipped with cytomorphism scanning module 11, snatch test-tube rack 4 on transferring module 12 and carrying module 6 and snatch to the concentrated module 10 of cell centrifugation in proper order, cytomorphism scanning module 11.

As shown in fig. 2 and fig. 3, the test tube 3 includes a tube body 301, the tube body 301 has two open ends and is of an internal hollow structure, a cover plug 302 is slidably and hermetically installed at an opening at one end of the tube body 301, the cover plug 302 is connected to a sampler 304 (the sampler 304 may be a spoon, a cotton swab or a handle-like structure) through a connecting column 303, a drain tube 310 is installed at an opening at the other end of the tube body 301, a plurality of positioning bosses 311 are installed outside the drain tube 310, a drain cap plug 312 is installed at an end cap of the drain tube 310, a liquid blocking plug (not shown) is installed inside the drain cap plug 312, the liquid blocking plug is of a convex conical structure, the liquid blocking plug is in movable sealing contact with the end of the drain tube 310 to block liquid in the drain tube 310 from being discharged through the drain hole 313, the drain hole 313 is ensured to be vertically downward, a guide 305 is formed by an opening on a side of the tube body 301 far from one end of the cover plug 302, a drain groove 305 is movably and a transparent structure is installed at a movable sealing position of the drain cap plug 306 for separating the drain tube 1 from the drain groove 312, and the drain tube 310, and an automatic cap plug assembly for separating the drain tube 310. Specifically, draw liquid groove 305 and body 301 junction to be equipped with and keep off liquid piece 307, keep off that liquid piece 307 is inside to be offered and is used for communicating the inside liquid flow path who draws liquid groove 305 with body 301 inside, and the height that liquid flow path is close to and draws liquid groove 305 department is lower than the height that is close to near body 301 department. A filter screen slot 308 is formed at an end of the liquid blocking member 307 close to the liquid guiding groove 305, and a filter screen 309 is inserted into the filter screen slot 308.

Specifically, as shown in fig. 11, the autosegregation assembly 9 is fixedly mounted on the test strip detection module 8 through a fixing base 901, and the autosegregation assembly 9 is located between the test strip rack conveying module 6 and the test strip dispensing module 7, the autosegregation assembly 9 includes a U-shaped mounting member 902, a telescopic driving member 903, a sliding member 904, a connecting member 905, a first fixing plate 906, a pulling claw 907 and a tightening column 908, the U-shaped mounting member 902 is fixedly mounted at the bottom of the fixing base 901, the sliding member 904 is slidably mounted inside the U-shaped mounting member 902, an end of the telescopic driving member 903 is connected with one end of the sliding member 904, the sliding member 904 is driven to move back and forth inside the U-shaped mounting member 902, the first fixing plate 906 is connected with the sliding member 904 through the connecting member 905, a plurality of tightening columns 908 and pulling claws 907 are mounted on the first fixing plate 906, the tightening columns 908 and the pulling claw 907 are arranged in a left-right staggered manner, an end of the tightening column 908 movably extends into the test strip rack 4 and contacts with a free end of the corresponding cap plug 312 on the test strip 3, a plurality of movable insertion grooves are formed inside the insertion grooves, and the cap plug 312 is inserted into the two sides of the test strip 3.

As shown in fig. 5, the test tube rack feeding module 5 includes a linear driving assembly 501, a rack 502, guide rails 503, a feeding guide groove 504, a slider and a test tube rack pusher 505, the rack 502 is fixed on the base 1, the guide rails 503 are arranged on two opposite sides inside the rack 502 along the length direction, the feeding guide groove 504 is formed in the top of the guide rails 503, the test tube rack pusher 505 is respectively connected with the guide rails 503 in a sliding manner, the test tube rack 4 is movably arranged on the guide rails 503, the bottom end of the test tube rack 4 is connected with the feeding guide groove 504 in a sliding manner, and the bottom end of the test tube rack pusher 505 is connected with the linear driving assembly 501.

As shown in fig. 6 and 7, the test tube rack conveying module 6 includes a first linear moving assembly 601, a sliding plate 602, a mounting seat 603, a rotating motor 604, a rotating rod 605, a connecting frame 606, an oscillator 607, an electrothermal thermostatic plate 608, a supporting plate 609 and an elastic clamping fixing member 610, the first linear moving assembly 601 is fixedly mounted on the top of the base 1, the first linear moving assembly 601 is connected with the sliding plate 602 located above the first linear moving assembly 601, the top of the sliding plate 602 is symmetrically provided with two mounting seats 603, the rotating rod 605 is rotatably connected between the two mounting seats 603, one end of the rotating rod 605 is in driving connection with the rotating motor 604, the connecting frame 606 is fixedly mounted on the rotating rod 605, the oscillator 607 and the electrothermal thermostatic plate 608 are sequentially connected to the top of the connecting frame 606, the top of the electrothermal thermostatic plate 608 is provided with the supporting plate 609 for placing the test tube rack 4, and the elastic clamping fixing member 610 for clamping and fixing the outer side of the test tube rack 4 is provided on the supporting plate 609. The top end of the support plate 609 is further provided with a drainage pushing cylinder 611, the output end of the drainage pushing cylinder 611 is connected with a second fixing plate 612, a plurality of drainage push rods 613 are arranged on the second fixing plate 612 side by side, and the end parts of the drainage push rods 613 are in movable contact with the cover plugs 302 at the ends of the test tubes 3 in the test tube rack 4.

As shown in fig. 8 and 9, the test strip dispensing module 7 includes a bottom plate 701, a fixed column 702, a platen 703, a dispensing manipulator 705, a second linear moving assembly 707, a mounting plate 708, a feeding plate 710, a test strip storage box 712, and a test strip pushing cylinder 713, where the bottom plate 701 is located on the base 1, the top of the bottom plate 701 is fixed with a plurality of fixed columns 702, the fixed columns 702 are respectively fixed with the platen 703 and the mounting plate 708, a plurality of grooves 704 for placing test strips are formed in parallel on the platen 703, the second linear moving assembly 707 is located on the bottom plate 701, the second linear moving assembly 707 is fixedly connected with the dispensing manipulator 705 located above the second linear moving assembly 707, the second linear moving assembly 707 drives the dispensing manipulator 705 to move in a direction perpendicular to the length of the test strips in the grooves 704, a bracket 706 is formed at a position where the top of the dispensing manipulator 705 corresponds to the grooves 704, and an opening for the dispensing manipulator 705 to pass through is formed on the platen 703; the top symmetry of mounting panel 708 is provided with two gibs 709, the relative both sides of delivery sheet 710 respectively with gib 709 sliding connection, delivery sheet 710 top is offered the holding tank 711 that is used for holding the test paper strip, the degree of depth of holding tank 711 is the thickness of a test paper strip, and the length direction of holding tank 711 is unanimous with the length direction of slot 704 on platen 703, test paper strip storage box 712 movable mounting is at the gib 709 top at the guide, test paper strip storage box 712 is disposable consumables, after inside test paper strip is used up, can change, test paper strip storage box 712 bottom sets up with the corresponding department opening of holding tank 711, delivery sheet 710 tip is connected with test paper strip propelling movement jar 713, under test paper strip propelling movement jar 713 drives, delivery sheet 710 moves towards being close to or keeping away from platen 703 direction, the opening that supplies partial shipment manipulator 705 to go up to pass is offered to the department on the delivery sheet 710.

In one embodiment, the test strip dispensing module 7 is linearly moved, a third linear moving assembly 714 is disposed on the top of the base 1, the third linear moving assembly 714 is drivingly connected to the bottom plate 701, and the third linear moving assembly 714 drives the bottom plate 701 to move in a direction approaching to or away from the rack transport module 6.

In another embodiment, the test strip sub-packaging module 7 is turned over at a certain angle, one end of the bottom plate 701, which is far away from the test strip rack conveying module 6, is hinged to the top of the base 1, an electric push rod is hinged to the inside of the base 1, and the output end of the electric push rod penetrates through the base 1 and is connected with the bottom of the bottom plate 701.

When specifically using, also can control test paper strip partial shipment module 7 and carry out linear movement to installing linear movement subassembly and upset subassembly simultaneously, also can drive it and carry out the upset of certain angle simultaneously.

As shown in fig. 10, the test strip detection module 8 is a CCD detection device 802, which is fixedly mounted on the base 1 through a supporting frame 801, the CCD detection device 802 includes a top plate located at the top of the supporting frame, a large-area light source and a CCD camera are mounted at the bottom of the top plate, the CCD camera is electrically connected to image analysis software in an external computer, and the automatic separation assembly 9 is mounted on the supporting frame 801.

As shown in fig. 12, the cell centrifugation and concentration module 10 includes a centrifugation container 1001, the bottom of the centrifugation container 1001 is installed on the base 1, a tray 1002 for fixedly installing the test tube rack 4 is provided inside the centrifugation container 1001, a centrifugal motor is provided at the bottom of the centrifugation container 1001, a driving end of the centrifugal motor passes through the centrifugation container 1001 and is connected with the bottom of the tray 1002, a protective cover 1003 is provided at a top opening of the centrifugation container 1001, in this embodiment, slide rails 1004 are symmetrically provided at the top opening of the centrifugation container 1001, the bottom of the protective cover 1003 is slidably connected with the slide rails 1004 through slide blocks, a protective cover pushing cylinder 1005 is provided at the top of the centrifugation container 1001, an output end of the protective cover pushing cylinder 1005 is connected with the top of the protective cover 1003

As shown in fig. 13, the cytomorphological scanning module 11 includes a workbench plate 1101, a support 1102 is arranged below the workbench plate 1101, an X-axis moving module 1103 is arranged at the top of the support 1102, the X-axis moving module 1103 is connected with the bottom of the workbench plate 1101, a Y-axis moving module 1104 is arranged at the top end of the workbench plate 1101, a test tube rack fixing plate 1105 is connected to the Y-axis moving module 1104, a limiting member for fixing and limiting the test tube rack 4 is arranged at the top of the test tube rack fixing plate 1105, a high power objective 1106 and a low power objective 1107 are arranged above the workbench plate 1101, a vertically arranged third fixing plate 1108 is arranged at the side of the workbench plate 1101, a Z-axis moving module 1109 is arranged on the third fixing plate 1108, and the outer sides of the high power objective 1106 and the low power objective 1107 are connected with the Z-axis moving module 1109 through a connecting seat. A waste losing port 2 is formed in the base 1, and a discarding box is arranged below the waste losing port 2.

The grabbing and transferring module 12 may be of an existing manipulator structure having a moving function.

The specific working steps are as follows:

1. taking materials

1.1, a doctor or a patient pours urine into a test tube 3 (forming a urine specimen);

1.2, taking a sample of leucorrhea secretion by using a cover plug 302 with cotton fibers, and plugging the cover plug 302 with the cotton fibers into an opening at the end part of the test tube 3, so that the leucorrhea sample on the cotton fibers is soaked in a diluent inside the test tube 3 (to form a leucorrhea specimen);

1.3, the patient takes a sample of the excrement by using the cover plug 302 with the sampling spoon, and then the cover plug 302 is plugged into the mouth of the test tube 3, so that the excrement sample on the sampling spoon is soaked in the diluent of the test tube 3 (a excrement sample is formed).

2. Feeding material

2.1, an operator inserts the test tubes 3 into the test tube racks 4, one test tube rack 4 can be inserted with a plurality of test tubes 3, and then the test tube racks 4 are placed on the guide rails 503 in the test tube rack feeding module 5;

2.2, the test tube rack pusher 505 automatically pushes the test tube rack 4 forwards, and pushes the test tube rack to the front port of the rack 502 to stop for waiting;

2.3, after the first linear moving component 601 drives the upper part of the sliding plate 602 to move to the empty position of the instrument, the rotating rod 605 is controlled by the rotating motor 604 to rotate until the supporting plate 609 forms an angle of 90 degrees with the base 1, and then the first linear moving component 601 drives the upper part of the sliding plate 602 to move to just align with the test tube rack 4 and stop;

2.4 the test tube rack pusher 505 pushes the test tube rack 4 into the supporting plate 609, the test tube rack 4 is clamped and fixed through the elastic clamping fixing piece 610 on the supporting plate 609, the first linear moving component 601 drives the upper part of the sliding plate 602 to move to an instrument vacancy and then rotate until the supporting plate 609 is parallel to the base 1, and the first linear moving component 601 drives the upper part of the sliding plate 602 to move forwards to a station of the test strip sub-packaging module 7;

2.5 mix the sample in tube 3 by shaking with shaker 607.

3. Automatic subpackage of chemical test paper strips, automatic dropping liquid of test tubes and CCD photographing detection

3.1, the lowermost test strip in the test strip storage box 712 enters the accommodating groove 711 on the feeding plate 710, the test strip pushing cylinder 713 pushes out the feeding plate 710, at the moment, the test strip is taken out, the second linear moving assembly 707 drives the sub-packaging manipulator 705 to the position below the feeding plate 710, the first bracket 706 on the sub-packaging manipulator 705 is aligned to the test strip in the accommodating groove 711 on the feeding plate 710, then the sub-packaging manipulator 705 is lifted to support the test strip and then moves back, and the test strip is placed in the first groove 704 on the platen 703; repeating the previous steps to push out a test strip from the test strip and put the test strip into the first groove 704 on the platen 703, and the test strip in the first groove 704 on the original platen 703 is moved into the second groove 704 on the platen 703, and sequentially subpackaging until the grooves 704 on the platen 703 are filled with the test strip;

3.2, the first linear moving component 601 drives the sliding plate 602 to move to the automatic separation component 9, the rotating motor 604 drives the test tube 3 in the test tube rack 4 on the supporting plate 609 to slowly rotate upwards back and forth until the test tube 3 is correspondingly inserted into the insertion groove on the pull claw 907, and then the pull claw 907 is pulled backwards by the telescopic driving component 903, at this moment, the drain tube 310 is separated from the liquid stopper in the drain cap plug 312, the drain hole 313 is in an open state, the drain push rod 613 drives the cover plug 302 to extrude into the tank body, the sample liquid in the test tube 3 is rapidly dripped out from the drain hole 313 on the drain cap plug 312, and the test strip dripped onto the platen 703 by the sample liquid has the following two modes:

mode 1: the supporting plate 609 is driven to form a right angle with the base 1 through the rotating motor 604, the third linear moving assembly 714 drives the test strip sub-packaging module 7 to move one step each time, a detection item block on a test strip on the sub-packaging module 7 moves to the position below a liquid outlet of each test tube 3 on the supporting plate 609, a sample liquid in each test tube 3 drips out of a liquid outlet hole 313 on a liquid outlet cap plug 312 onto the detection item block on each test strip, the upper action is circulated until all the detection item blocks on the test strip are dripped with the sample liquid, and the purpose that a plurality of test tubes 3 drip the sample liquid to a plurality of test strips at the same time is achieved;

mode 2: one end of the test strip sub-packaging module 7 is jacked up through an electric push rod and is inclined to form an angle of about 45 degrees, meanwhile, the supporting plate 609 is driven to rotate through the rotating motor 604 until the liquid discharge hole 313 on the liquid discharge cap plug 312 of each test tube 3 is aligned with the upward end of the test strip on the supporting plate 609, and the sample liquid slowly flows downwards to each detection item block along one side of the test strip.

3.3 waiting for 1 minute after dropping the liquid, carrying out chemical reaction, then starting a large plane light source in the test strip detection module 8 for illumination, and scanning and photographing by a CCD camera and then transmitting the image into a computer for analysis;

3.4 after the test strip is analyzed, the dispensing manipulator 705 continues to jack up and put down to reciprocate to push the test strip on the platen 703 into the slope at the edge of the platen 703 in sequence, and the test strip slides into the waste box from the slope.

4. Centrifugation for cell concentration

After the dropping liquid goes up the chemical test paper strip, the test-tube rack conveying module 6 is leveled up and then moves forward to autosegregation subassembly 9 department, test tube 3 that will be located in test-tube rack 4 on layer board 609 corresponds with the tight post 908 in top, promote the tight post 908 in top forward through flexible driving piece 903, at this moment, the tight post 908 in top inserts inside test-tube rack 4 to with the contact of flowing back cap stopper 312 free end on the test tube 3 that corresponds, close drain pipe 310 tip and the fender liquid stopper contact lid in flowing back cap stopper 312, close outage 313.

The first linear moving component 601 drives the sliding plate 602 to move to the side of the cell centrifugal concentration module 10, the test tube rack 4 is grabbed by the grabbing and moving module 12 and placed on the tray 1002 in the centrifugal container 1001, the clamping and pressing structure on the tray 1002 clamps the test tube rack 4, the protective cover pushing cylinder 1005 drives the protective cover 1003 to be closed, and after centrifugal concentration is completed, the protective cover pushing cylinder 1005 drives the protective cover 1003 to be opened.

5. Microscopic analysis of cell morphology

Snatch and transfer module 12 and snatch test-tube rack 4 on the tray 1002 in the centrifugal vessel 1001, move to on the test-tube rack fixed plate 1105 in the cytomorphology scanning module 11, it is spacing with test-tube rack 4 is fixed through the locating part, cover 306 department in scanning test tube 3 through high power objective 1106 and low power objective 1107, Z axle removes module 1109 and drives objective and focuses on, the X axle, Y axle removes module 1104 and drives test tube 3 on test-tube rack fixed plate 1105 and remove and scan, the back is shot in the scanning and spreads into the computer and carry out cell identification analysis, after the analysis is accomplished, snatch and transfer module 12 and snatch test-tube rack 4, and remove test-tube rack fixed plate 1105, it loosens test-tube rack 4 to snatch test-tube rack 4, test-tube rack 4 gets into to abandoning the case through losing useless mouth 2 on the base 1.

To sum up, the multi-project body fluid analyzer of the utility model has the following characteristics:

3. the instrument is mainly characterized in that a suction-needle-free and liquid-pipeline-free technology is adopted, all test strip chemical examination and cytomorphological examination are automatically completed in one test tube, and the detection can be completed only by moving the test tube to different stations in the whole instrument processing process;

4. the instrument processes and detects a plurality of samples at one time by taking a plurality of test tube samples on the test tube rack as an operation unit, and can finish various detection items as long as the test tube rack is moved to each detection module, thereby greatly saving the detection time and reducing the complexity of the instrument;

3. each detection module of this instrument has simplified the instrument for the sharing of various specimens, practices thrift a large amount of costs, has realized that many samples multinomial detect as an organic whole: including body fluid samples such as urine, leucorrhea, stool and the like; multiple chemical test paper and microscopic cell morphology multi-item detection;

4. the detection technology aspect is as follows: the test strip detection module adopts a mode of combining a CCD camera with a large-area light source and computer image analysis software innovatively, can detect a plurality of test strips and a plurality of samples simultaneously, greatly improves the analysis accuracy and improves the detection speed by dozens of times compared with the mode that a diode, an image sensor and a lower microcomputer chip are used as detection devices in the market; the cell centrifugal concentration module adopts unique frame type centrifugation, a test tube rack provided with a plurality of test tubes is automatically placed in a centrifugal container through the grabbing and transferring module at one time without inserting one test tube into the centrifugal container, the examination of the centrifugal sediment cells of the whole urine is realized, and the accuracy of the detection is improved;

5. in the test strip split charging module test strip feeding process, a box-type cartridge clip is innovatively adopted for horizontally pushing and feeding, so that the phenomena of time consumption in material taking, askew moving, reverse moving, strip clamping, strip falling and the like caused by drum-type feeding in the market are avoided;

6. full automation: all items of all specimens are automatic, an operator only needs to put test tubes with sample liquid into a test tube rack, the test tube rack is installed on a test tube rack feeding module, test strip storage boxes with 50-100 chemical test strips are loaded into a test strip subpackaging module, and other items are completed by an instrument in a full-automatic mode: automatic feeding, mixing, dropping liquid, constant temperature, test strip detection, centrifugation, microscopic cell morphology detection, waste material abandoning, realize unmanned on duty full automatization.

The instrument is a full-automatic instrument, and can be suitable for large 3A hospitals and small hospitals; urine, leucorrhea and excrement are 3 conventional items in hospitals, so the demand is particularly large; in addition, the instrument has a simple structure, all the sample modules are shared, and the production cost is extremely low; and the instrument has the advantages of less stable faults, high detection speed and wide market prospect.

It is right to have used specific individual example above the utility model discloses expound, only be used for helping to understand the utility model discloses, not be used for the restriction the utility model discloses. To the technical field of the utility model technical personnel, the foundation the utility model discloses an idea can also be made a plurality of simple deductions, warp or replacement.

Claims (10)

1. A multi-project body fluid analyzer is characterized by comprising a base, test tubes, a test tube rack feeding module, a test tube rack conveying module, a test strip split charging module, a test strip detection module, a cell centrifugal concentration module, a cell morphology scanning module and a grabbing and transferring module;

the utility model discloses a cell test tube rack, including test-tube rack, base top, test-tube rack movable mounting, test-tube rack feeding module, test-tube rack module side is equipped with test-tube rack transport module, test-tube rack feeding module drive the test-tube rack removes, and will the test-tube rack propelling movement is installed extremely on the test-tube rack transport module, the base top is followed be equipped with test paper strip partial shipment module and the concentrated module of cell centrifugation in the direction of transfer of test-tube rack transport module, the test-tube rack transport module drives the test-tube rack removes and rotates, and control test tube in the test-tube rack with the test paper strip in the test paper strip partial shipment module is corresponding, test paper strip detection module is located on the base, and is located test paper strip partial shipment module top, the concentrated module outside of cell centrifugation is equipped with cell morphology scanning module, snatch the transfer module and carry the test-tube rack in the module to in proper order snatch to the concentrated module of cell centrifugation, cell morphology scanning module.

2. The multi-project body fluid analyzer as claimed in claim 1, wherein the test tube comprises a tube body, the tube body is a hollow structure with two open ends, a cap plug is slidably and sealingly mounted at the open end of one end of the tube body, a fluid discharge tube is disposed at the open end of the other end of the tube body, a fluid discharge cap plug is disposed at the end of the fluid discharge tube, a fluid blocking plug is disposed inside the fluid discharge cap plug, the fluid blocking plug is in movable and sealing contact with the end of the fluid discharge tube, a fluid discharge hole is disposed on the side surface of the fluid discharge cap plug, a fluid guide groove is formed at the open end of the tube body on the side surface away from the cap plug, a cover body in a transparent structure is movably and sealingly mounted at the fluid guide groove, and an automatic separation assembly for separating and closing the fluid discharge tube and the fluid blocking plug in the fluid discharge cap plug is disposed on the base.

3. The multi-project body fluid analyzer of claim 2 wherein a liquid blocking member is disposed at a connection between the liquid introducing tank and the tube, a liquid flow passage for communicating the interior of the tube with the liquid introducing tank is disposed in the liquid blocking member, and a height of the liquid flow passage near the liquid introducing tank is lower than a height near the tube.

4. The multi-project body fluid analyzer of claim 3, wherein the end of the fluid blocking member near the fluid-guiding groove is provided with a filter screen slot, and a filter screen is inserted into the filter screen slot.

5. The multi-project body fluid analyzer of any one of claims 2 to 4, wherein the autosegregation assembly is fixedly mounted on the test strip testing module through a fixing seat, and is located between the test strip rack conveying module and the test strip dispensing module, the autosegregation assembly comprises a U-shaped mounting member, a telescopic driving member, a sliding member, a connecting member, a first fixing plate, a pulling claw and a tightening pillar, the U-shaped mounting member is fixedly mounted at the bottom of the fixing seat, the sliding member is slidably mounted inside the U-shaped mounting member, an end of the telescopic driving member is connected with one end of the sliding member to drive the sliding member to move back and forth inside the U-shaped mounting member, the first fixing plate is connected with the sliding member through the connecting member, a plurality of tightening pillars and pulling claws are mounted on the first fixing plate, the tightening pillars and the pulling claw are staggered back and forth, an end of the tightening pillar can movably extend into the test strip rack and contact with a free end of a corresponding cap plug on the test tube, a plurality of movable insertion grooves are formed inside the pulling claw, and the liquid discharge plug on the test tube is inserted into the cap plug.

6. The multi-project body fluid analyzer according to claim 1, wherein the test tube rack conveying module comprises a first linear moving assembly, a sliding plate, a mounting seat, a rotating motor, a rotating rod, a connecting frame, an oscillator, an electrothermal thermostatic plate, a supporting plate and an elastic clamping fixing member, the first linear moving assembly is fixedly mounted on the top of the base, the first linear moving assembly is connected with the sliding plate above the first linear moving assembly, two mounting seats are symmetrically arranged on the top of the sliding plate, the rotating rod is rotatably connected between the two mounting seats, one end of the rotating rod is in driving connection with the rotating motor, the connecting frame is fixedly mounted on the rotating rod, the oscillator and the electrothermal thermostatic plate are sequentially connected to the top end of the connecting frame, the supporting plate for placing the test tube rack is arranged on the top end of the electrothermal thermostatic plate, the elastic clamping fixing member for clamping and fixing the outer side of the test tube rack is arranged on the supporting plate, a fluid discharging pushing cylinder is further arranged on the top end of the supporting plate, the output end of the fluid discharging pushing cylinder is connected with a second fixing plate, a plurality of push rods are arranged side by side, and the end of the push rods is movably contacted with the cover plug of the fluid discharging end of the test tube inside the test tube rack.

7. The multi-project body fluid analyzer as claimed in claim 1, wherein the test strip dispensing module includes a bottom plate, a fixed column, a platen, a dispensing manipulator, a second linear moving component, a mounting plate, a feeding plate, a test strip storage box and a test strip pushing cylinder, the bottom plate is located on the base, the top of the bottom plate is fixed with a plurality of the fixed columns, the platen and the mounting plate are respectively fixed on the fixed columns, a plurality of grooves for placing test strips are formed in the platen side by side, the second linear moving component is located on the bottom plate and is fixedly connected with the dispensing manipulator located above the second linear moving component, the second linear moving component drives the dispensing manipulator to move along a direction perpendicular to the length of the test strips in the grooves, a supporting groove is formed at a position of the top of the dispensing manipulator corresponding to the grooves, and an opening for the dispensing manipulator to pass through is formed in the platen; the test paper strip feeding mechanism comprises a mounting plate, a feeding plate, a test paper strip storage box, a feeding plate and a feeding manipulator, wherein the feeding plate is movably arranged at the top of the mounting plate, a containing groove used for containing the test paper strip is formed in the top of the feeding plate, the length direction of the containing groove is consistent with the length direction of a groove in a platen, the test paper strip storage box is mounted on the mounting plate, the bottom of the test paper strip storage box is provided with an opening corresponding to the containing groove, the end part of the feeding plate is connected with the test paper strip pushing cylinder, the feeding plate moves towards or away from the platen and is located at the containing groove, and an opening for the split charging manipulator to pass through the feeding plate is formed in the containing groove.

8. The multi-item bodily fluid analyzer of claim 7 wherein a third linear movement assembly is disposed on the top of the base, the third linear movement assembly being drivingly connected to the base plate, the third linear movement assembly moving the base plate toward or away from the tube rack transport module.

9. The multi-project body fluid analyzer of claim 7, wherein one end of the bottom plate, which is far away from the test tube rack delivery module, is hinged to the top of the base, an electric push rod is hinged to the inside of the base, and an output end of the electric push rod penetrates through the base and is connected to the bottom of the bottom plate.

10. The multi-project body fluid analyzer of claim 1, wherein the cytocentrifugal concentration module comprises a centrifugal container, the bottom of the centrifugal container is mounted on the base, a tray for fixedly mounting the test tube rack is arranged in the centrifugal container, a protective cover is arranged at the opening of the top of the centrifugal container, a centrifugal motor is arranged at the bottom of the centrifugal container, and the driving end of the centrifugal motor penetrates through the centrifugal container and is connected with the bottom of the tray

The cell morphology scanning module includes the work platen, work platen below is equipped with the support, the support top is equipped with X axle moving module, X axle moving module is connected with the work platen bottom, the work platen top is equipped with Y axle moving module, be connected with the test-tube rack fixed plate on the Y axle moving module, test-tube rack fixed plate top is equipped with and is used for fixing spacing locating part to the test-tube rack, work platen top is equipped with high power objective and low power objective, the work platen side is equipped with the third fixed plate of vertical setting, be equipped with Z axle moving module on the third fixed plate, high power objective and low power objective outside are passed through the connecting seat and are linked to each other with Z axle moving module.

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