CN216677078U - Consumable material for PRP preparation with adjustable boundary liquid level - Google Patents

Abstract

The utility model discloses a consumable material for PRP preparation with an adjustable boundary liquid level, which comprises an outer tube body and a bottom cover, wherein the bottom end of the outer tube body is open and movably matched with the bottom cover through a thread pair, and a bottom sealing ring is arranged between the outer tube body and the bottom cover. The utility model can realize the adjustment of the liquid level at the throat bin by matching the bottom cover with the bottom sealing ring, namely realize the adjustment of the position of each component layered interface after the whole blood centrifugation, has few accessories, simple structure and good sealing performance, thereby reducing the cost of consumable materials for PRP preparation.

Description

Consumable material for PRP preparation with adjustable boundary liquid level

Technical Field

The utility model relates to the technical field of biomedicine and medical instruments, in particular to a consumable material for preparing a PRP (platelet-rich plasma) with an adjustable boundary liquid level.

Background

Platelet-rich plasma (PRP) is rich in various bioactive substances such as growth factors, cytokines and antibacterial peptides, has the effects of promoting cell proliferation, differentiation, matrix synthesis, tissue regeneration and repair and the like, and plays an important role in regenerative medicine. The preparation methods of PRP are more, and at present, there is no unified standard, and the following mature methods are introduced in the literature, "expert consensus on autologous platelet-rich plasma preparation technology" (single Guiqiu, etc.): (1) the method comprises the following steps of (1) collecting and preparing PRP by a blood component single collector, (2) collecting and preparing PRP by a blood bag, (3) preparing PRP by a PRP special separation set, and (4) manually collecting whole blood by a test tube method to prepare PRP.

Wherein, the separation operation is carried out to the third method adopts the secondary gradient centrifugation method more, and its main defect is, twice centrifugal operation respectively needs one set of centrifuging tube as the preparation consumptive material, and is with high costs, and the medical waste that produces is many, and move the liquid process moreover troublesome, and more serious has increased the pollution risk.

Patent document (CN 203609925U, closed platelet concentrator) discloses a closed platelet concentrator, which is designed skillfully to complete two times of centrifugation in one set of consumable. Particularly, the lower bottle body of the concentrator has the function of adjusting a liquid level interface, and the concrete structure is as follows: "a screw cap, which is sleeved on the lower part of the lower bottle body and can rotate freely relative to the lower bottle body, a screw body is arranged in the center of the inner part of the screw cap in a protruding way, a suspension plug made of rubber material is sleeved in the screw cap in a screw way by utilizing the screw body, the size of the suspension plug is almost consistent with the inner diameter of the lower bottle body, so that the level of the suspension plug can be changed by the screw control of the screw cap, and the suspension plug can form an upward pushing effect on the blood in the lower bottle body in the upward lifting process. Obviously, the structure is complex, the sealing structure also needs to be simple, and a precise process is needed to ensure the sealing performance, so the cost is high.

SUMMERY OF THE UTILITY MODEL

In order to overcome the defects of the closed platelet concentrator, the utility model provides a consumable material with adjustable boundary liquid level for preparing PRP.

The technical scheme adopted by the utility model is as follows: the PRP consumable with the adjustable boundary liquid level comprises an outer pipe body and a bottom cover, wherein the bottom end of the outer pipe body is open and is movably matched with the bottom cover through a thread pair, and a bottom sealing ring is arranged between the outer pipe body and the bottom cover.

Preferably, the following components: the bottom cover is an external screw cover, and the bottom sealing ring is arranged between the outer peripheral wall of the outer tube body and the inner peripheral fold of the bottom cover.

Preferably: the bottom sealing ring is close to the pipe orifice of the outer pipe body, and the bottom sealing ring is arranged below the thread pair.

Preferably: the section of the sealing ring is dumbbell-shaped.

Preferably: the peripheral wall of the bottom cover is provided with at least two clamping surfaces.

Preferably: the outer tube body is provided with a window for photoelectric detection.

Preferably: the end wall of the bottom cover is an inner concave surface.

The utility model has the following beneficial effects: the utility model can realize the adjustment of the liquid level at the throat bin by matching one bottom cover with the bottom sealing ring, namely, the adjustment of the position of the interface of each component layer after whole blood centrifugation, has few accessories, simple structure and good sealing performance, thereby reducing the cost of consumable materials for PRP preparation.

Drawings

FIG. 1 is a perspective view of a consumable for a centrifuge tube according to an embodiment of the present invention.

FIG. 2 is a schematic front view of a consumable for a centrifuge tube according to an embodiment of the present invention.

FIG. 3 is a cross-sectional view of the consumable A-A of the centrifuge tube according to the embodiment of the present invention.

FIG. 4 is a cross-sectional view of consumable B-B of a centrifuge tube according to an embodiment of the present invention.

FIG. 5 is an enlarged view of the consumable part at C in the centrifuge tube according to the embodiment of the present invention.

An outer tube body 1, an upper chamber body 101, a lower chamber body 102, a throat chamber 103, an injection port 104, a vent 105, a rubber plug 106, a bacteria-blocking film 107, a suction port 108, a diaphragm 109 and a window 110; a central liquid taking pipe 2 and a liquid taking pipe opening 201; a bottom cover 3; and a bottom seal ring 4.

Detailed Description

The present invention will be further explained with reference to the following examples and the accompanying drawings.

As shown in figures 1-5, an outer tube body 1 of the centrifuge tube consumable is divided into an upper bin body 101 and a lower bin body 102, and the upper bin body 101 and the lower bin body 102 are communicated into a whole through a throat bin 103. The built-in central liquid intaking pipe 2 that has of outer tube shaft 1, the lower extreme of central liquid intaking pipe 2 is for getting liquid mouth of pipe 201, is located the throat storehouse 103, and the upper end of central liquid intaking pipe 2 welds or bonds fixedly with the roof of last storehouse body 101 to with suction port 108 intercommunication on the roof. The lower part of the lower bin body 102 is open and is provided with a bottom cover 3 in threaded connection, and a bottom sealing ring 4 is arranged between the bottom cover 3 and the lower bin body 102. The volume of the outer tube body 1, namely the position of the interface of the platelet concentrate and the red blood cells can be adjusted by rotating the screw cap 3. Therefore, after the whole blood from different sources is centrifuged, the liquid taking pipe port 201 of the central liquid taking pipe 2 is just 1-2 mm above the interface of the platelet concentrate and the red blood cells. It should be noted that in some cases, a certain amount of red blood cells may be contained in the platelet rich plasma, and the port 201 of the central liquid withdrawal tube 2 may be located about 1mm below this interface.

As shown in fig. 5, the bottom sealing ring 4 between the bottom cover 3 and the lower chamber body 102 has a dumbbell-shaped cross section and a large sealing area. The sealing structure has two advantages, namely, good sealing performance is provided, leakage and pollution are avoided, a certain friction force is kept, the bottom cover 3 cannot rotate easily, the volume of the outer tube body 1 is stable, and the stability and the reliability of the device are guaranteed.

As shown in fig. 1, the circumferential wall of the bottom cover 3 has a plurality of planes, which facilitates the automatic rotation after the mechanical clamping. Correspondingly, as shown in fig. 1, a window 110 corresponding to the liquid taking nozzle 201 is arranged on the throat bin 103, the photoelectric sensor detects through the window 110, and recognizes red blood cells on the lower layer by using the light transmittance, so as to distinguish the interface between the platelet concentrate and the red blood cells, and further control the mechanical device to drive the bottom cover 3, thereby completing the adjustment of the liquid level, and enabling the interface and the liquid taking nozzle 201 at the lower end of the central liquid taking tube 2 to be at a specific position. The inner diameter of the throat chamber 103 is generally 1/3 of the inner diameters of the upper chamber body 101 and the lower chamber body 102, so that the platelet concentrate can show a higher height for detection and operation.

As shown in FIGS. 1 to 5, an injection port 104 and a vent 105 are formed on the top of the peripheral wall of the upper chamber body 101. The injection port 104 is provided with a rubber plug 106, the rubber plug 106 is fastened through a compression ring, and the compression ring is fixed with the upper bin body 101 into a whole by ultrasonic welding or gluing. The air vent 105 is provided with a bacteria-blocking film 107 to make the air vent 105 play a role in inhibiting bacteria and ventilating. A diaphragm 109 is arranged at the suction port 108 and is formed by injection molding. The rubber plug 106, the diaphragm 109 and the bacteria-blocking film 107 respectively play a role in sealing and bacteria-blocking. The rubber stopper 106 can be pierced by a needle when whole blood is injected, the sealing can be kept during centrifugation, the diaphragm 109 is kept sealed before suction, and the diaphragm is broken once when platelet rich plasma is sucked.

As shown in figures 3-4, the liquid taking pipe opening 201 at the lower end of the central liquid taking pipe 2 is attached to the inner wall of the throat bin 103, and the structure utilizes the cohesion and the adsorbability of liquid, so that the suction effect can be improved, and the platelet concentrate is prevented from remaining in the outer pipe body 1.

In addition, the centrifuge tube consumable of the embodiment is manufactured by adopting the process of injection molding and ultrasonic welding/bonding, and has the advantages of simple and reliable process; the material is medical grade transparent material, such as PVC, PC, ABS, etc.

Similarly, the bottom cap 3 of the present embodiment may be applied to the closed platelet concentrator disclosed in patent document 1 or other type of consumable for PRP preparation.

It should be understood that the above-described embodiments of the present invention are merely examples for illustrating the present invention, and are not intended to limit the embodiments of the present invention. Other obvious changes or modifications which are obvious to be covered by the spirit of the utility model are also covered by the protection scope of the utility model.

Claims (7)

1. The consumable for PRP preparation with adjustable boundary liquid level is characterized by comprising an outer tube body (1) and a bottom cover (3), wherein the bottom end of the outer tube body (1) is open and is movably matched with the bottom cover (3) through a thread pair, and a bottom sealing ring (4) is arranged between the outer tube body (1) and the bottom cover (3).

2. The consumable for PRP preparation with adjustable boundary liquid level according to claim 1, wherein: the bottom cover (3) is an external screw cover, and the bottom sealing ring (4) is arranged between the outer peripheral wall of the outer tube body (1) and the inner peripheral folds of the bottom cover (3).

3. The consumable for PRP preparation with adjustable boundary liquid level according to claim 2, which is characterized in that: the bottom sealing ring (4) is close to the pipe orifice of the outer pipe body (1), and the bottom sealing ring (4) is arranged below the thread pair.

4. The consumable for PRP preparation with adjustable boundary liquid level according to claim 2, comprising: the section of the sealing ring (4) is dumbbell-shaped.

5. The consumable for PRP preparation with adjustable boundary liquid level according to claim 2, which is characterized in that: the peripheral wall of the bottom cover (3) is provided with at least two clamping surfaces.

6. The consumable for PRP preparation with adjustable boundary liquid level according to claim 5, which is characterized in that: the outer tube body (1) is provided with a window (110) for photoelectric detection.

7. The consumable for PRP preparation with adjustable boundary liquid level according to claim 1, which is characterized in that: the end wall of the bottom cover (3) is an inner concave surface.

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