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CN202393731U - Portable non-invasive blood glucose monitor - Google Patents

Portable non-invasive blood glucose monitor Download PDF

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Publication number
CN202393731U
CN202393731U CN2011202977272U CN201120297727U CN202393731U CN 202393731 U CN202393731 U CN 202393731U CN 2011202977272 U CN2011202977272 U CN 2011202977272U CN 201120297727 U CN201120297727 U CN 201120297727U CN 202393731 U CN202393731 U CN 202393731U
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CN
China
Prior art keywords
blood glucose
electrochemical reaction
unit
saliva
collecting portion
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn - After Issue
Application number
CN2011202977272U
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Chinese (zh)
Inventor
鲍文生
张勐
张伟杰
柳月双
钟旻
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SUZHOU YUEAN MEDICAL ELECTRONICS CO Ltd
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SUZHOU YUEAN MEDICAL ELECTRONICS CO Ltd
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Priority to CN2011202977272U priority Critical patent/CN202393731U/en
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Publication of CN202393731U publication Critical patent/CN202393731U/en
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  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)

Abstract

The utility model discloses a portable non-invasive blood glucose monitor, which comprises a salivary glucose density obtaining device and a processing main machine. The salivary glucose density obtaining device is provided with a sample collection portion, an electrochemical reaction tank and an electric signal transmission wire. An insulation layer is arranged on the outer periphery of the electrochemical reaction tank. The processing main machine comprises a signal processing unit, a processor, a storage unit and a display unit with a control and input function. Food category, feeding number and feeding time are input in the display unit. The processor calculates feeding total glucose content according to glucose contained by various food recorded in a diet database, and detects time sections according to the feeding time and the blood glucose value obtained in the above step to obtain comprehensive blood glucose index and display the index on a displaying unit. The monitor enables a patient to interact with a detector main machine by use of a touch screen and simultaneously shows a visual blood glucose parameter in fixing mode according to the self built database, and the patient can intuitively learn self blood glucose conditions according to the parameter.

Description

A kind of portable non-invasive blood sugar monitoring instrument
Technical field
The utility model relates to a kind of portable blood sugar detector, relates in particular to a kind of portable non-invasive blood-sugar detecting instrument.
Background technology
Change along with remarkable decline of modern humans's labour intensity and eating habit; And the aggravation of aging population; The incidence of disease of diabetes rises rapidly, and the influence that diabetes and complication thereof caused has become one of the serious public health problem that must face countries in the world.Increasing diabetic need every day repeatedly blood sugar in the body is carried out timing or monitor at any time according to physical condition, general patient need detect 5-6 time blood sugar every day, and the blood glucose meter of being sold on the existing market is that wound is arranged mostly; Need acupuncture treatment to get blood,, will cause the needle stick injury about 2000 times in 1 year; So many wound not only brings very big inconvenience to the patient, makes the patient suffer misery; But also might cause wound infection, be unfavorable for the frequent detection of blood sugar.Blood sugar does not have the focus that wound detects becomes domestic and international blood sugar test research.
To the major defect that the wound blood sugar test is arranged, people begin diversion to efficient, on Woundless blood sugar detects easily.The nothing wound detection method of now having come out a lot mainly is through scanning human body skin, hypodermis liquid or blood etc.But because disturbing factor is a lot of in the human body, blood sugar does not have single, special absorption peak yet, makes optical means accuracy in detection and sensitivity all not satisfactory.
The utility model content
The utility model is to the proposition of above problem, and a kind of portable non-invasive blood sugar monitoring instrument of development has: saliva sugar concentration deriving means and processing host;
Said saliva sugar concentration deriving means has:
Be configured for gathering the sample collecting portion of saliva sample by polyurethane foam;
Be filled with lactochrome adenylic acid complexing GDH, the saliva sample that is used to make sample collecting portion to gather carries out the electrochemical reaction groove of electrochemical reaction;
Be connected on the electrochemical reaction groove, be used for the electric signal transfer wire of the conduction of current that produces in the electrochemical reaction groove to the main frame;
Said sample collecting portion is fixed on the electrochemical reaction groove;
Said electrochemical reaction groove outside is provided with insulation course.
Said processing host comprises:
The physics and chemistry conversion of signals that said saliva sugar concentration deriving means is obtained is the signal processing unit of electric signal;
Be pre-stored with the patient individual blood glucose level data storehouse that has the blood sugar secure threshold, the storage unit of healthy blood glucose level data storehouse and diet database;
The display unit that has control and input function; And
The electric signal that signal processing unit obtained is changed into blood glucose value; A plurality of blood glucose values of the former period of individual blood glucose level data storehouse record in this blood glucose value and the storage unit are interrelated, draw individual blood glucose curve, and call the blood glucose level data of corresponding period in the said healthy blood glucose level data storehouse; Drafting is with reference to blood glucose curve; With said blood glucose value, blood glucose curve and be presented on the display unit, the processor of the correlation parameter of each database in the updated stored unit simultaneously with reference to blood glucose curve;
The lactochrome adenylic acid complexing GDH of filling in the said electrochemical reaction groove is wrapped on the glass nano microballoon.
Also comprise and be used to monitor the threshold alerts unit whether saliva that sample collecting portion gathers reaches collection capacity; Said threshold alerts unit comprises: be set in around the sample collecting portion humidity sensor that the humidity of sample collecting portion is detected;
Connect humidity sensor, the detected humidity value of humidity sensor is compared with preset threshold, after humidity value reaches setting threshold, send the single-chip microcomputer of alerting signal;
Connect single-chip microcomputer, the alerting signal that single-chip microcomputer sends is carried out corresponding alarm unit;
Be connected on the loop that humidity sensor, single-chip microcomputer and alarm unit constitute, to the unlatching of circuit or close the switch of controlling.
Also have: said processing host also has the wave point that links to each other with said processor.
The advantage of the said portable non-invasive blood sugar monitoring instrument of the utility model is: through the use of touch-screen; Can make patient and detector main frame interactive; According to the database of building in self, fixedly go out blood sugar parameter intuitively simultaneously, can get information about the blood glucose condition of self according to this parameter patient.In addition, this device also has simple in structure, is convenient to produce, and with low costly is suitable for extensive popularization.
Description of drawings
Fig. 1 is the structured flowchart of the utility model
Fig. 2 is the synoptic diagram I of the utility model display unit
Fig. 3 is the synoptic diagram II of the utility model display unit
Fig. 4 is the synoptic diagram of the saliva sugar concentration deriving means of the utility model
Fig. 5 is the structured flowchart of the saliva sugar concentration deriving means control gear of the utility model
Among the figure: 1. sample collecting portion, 2. electrochemical reaction groove, 3. electric signal transfer wire, 4. threshold alerts unit, 401. humidity sensors, 402. single-chip microcomputers, 403. alarm units, 404. switches, 5. signal processing unit, 6. processor, 7. storage unit, 8. display unit, 9. display unit.
Embodiment
Fig. 1 is the structured flowchart of the utility model; Fig. 4 is the synoptic diagram of the saliva sugar concentration deriving means of the utility model; Fig. 5 is the structured flowchart of the saliva sugar concentration deriving means control gear of the utility model; By Fig. 1, a kind of portable non-invasive blood sugar monitoring instrument shown in 4,5 mainly has saliva sugar concentration deriving means and the processing host that is used to obtain the saliva sugar content;
The described saliva sugar of preferred the utility model as shown in Figure 4 concentration deriving means; Comprise: the sample collecting portion 1 (the utility model adopts Soft PU foam, is because Soft PU foam has good bio-compatibility and high-speed and high-efficiency absorbability) that is configured for gathering saliva sample by polyurethane foam; (the utility model adopts lactochrome adenylic acid complexing GDH to be filled with lactochrome adenylic acid complexing GDH; Because of GDH has anti-oxidant; For the high characteristics of glucose selectivity, the false positive reaction of having avoided the interference because of maltose, galactose and wood sugar to cause.), the saliva sample that is used to make sample collecting portion 1 to gather carries out the electrochemical reaction groove 2 of electrochemical reaction; Be connected on the electrochemical reaction groove 2; Be used for the electric signal transfer wire 3 of the conduction of current that produce in the electrochemical reaction groove 2 to the main frame; Main frame can adopt a coulomb coulometry; I.e. reaction produces whole electric currents and all includes calculating in, ensures that the LG sample still can be by accurate detection, and calculates through related function saliva sugar concentration and blood sugar concentration are informed the user; Said sample collecting portion 1 is fixed on the electrochemical reaction groove 2; Said electrochemical reaction groove 2 outsides are provided with insulation course 201, ensure that all kinetic currents are all uploaded seizure; The lactochrome adenylic acid complexing GDH of filling in the said electrochemical reaction groove 2 is wrapped in (the Nano microsphere diameter is about 5-50nm) on the glass nano microballoon, can increase reaction area and glucose response efficient like this; Lactochrome adenylic acid complexing GDH in the said electrochemical reaction groove 2 or the glass nano microballoon that is enclosed with lactochrome adenylic acid complexing GDH are dissolved in the phosphate-buffered saline damping fluid of pH value 7.4.
Because of the result of the amount of gathering saliva and detection has direct relation (magnitude of current as the sample of same people microlitre saliva of same stages 100 produces is fixed); Therefore for obtaining testing result more accurately; After sample collecting portion collects the ormal weight saliva sample; Corresponding prompt must be arranged, and the amount of prompting collected specimens is enough.Therefore this device this device as shown in Figure 5 also comprises and is used to monitor the threshold alerts unit 4 whether saliva that sample collecting portion 1 gathers reaches collection capacity; Said threshold alerts unit 4 comprises: be set in around the sample collecting portion 1; The humidity sensor 401 that the humidity of sample collecting portion 1 is detected is according to the solubleness of collection portion absorption of water and saliva; The corresponding position of the harvester of same specification is the identical principle of its humidity under the identical situation of collection capacity; And the employing humidity sensor, present embodiment adopts capacitive humidity sensor; According to the sample collecting portion 1 of different model with sensor settings in corresponding position, this process need parameter testing, debug process is collection capacity with the signal of the conduction process to coupling, is techniques well known, is not elaborated here); Connect humidity sensor 401, humidity sensor 401 detected humidity values are compared with preset threshold, after humidity value reaches setting threshold, send the single-chip microcomputer 402 of alerting signal; Connect single-chip microcomputer 402, the alerting signal that single-chip microcomputer 402 sends is carried out corresponding alarm unit 403, said alarm unit 403 can also can be luminous warning for audible alarm, perhaps has the function of sound and light alarm simultaneously; Be connected on the loop that humidity sensor 401, single-chip microcomputer 402 and alarm unit 403 constitute, to the unlatching of circuit or close the switch of controlling 404.
Preferably; Processing host as shown in Figure 1 comprises: the physics and chemistry conversion of signals that said saliva sugar concentration deriving means is obtained is the signal processing unit 5 of electric signal; Because the electric conductivity of saliva (sugar juice) and saliva sugar concentration have certain relation; As a preferred implementation, said signal processing unit 5 mainly converts 6 electric signal that can discern of processor into getting the enclosed pasture electricity in the said sugar juice.
Because processor 6 need be born the signal conversion processing, work such as data base call modification, graphic interface demonstration and touch control, bearing of task is heavy; Current data traffic is big, and is so general single-chip microcomputer is not competent, preferred; Here select homemade ARM Cortex A8 architecture processor " auspicious core little 2918 ",, have enough powerful calculation process as the previous generation compacting instruction set processor; Simultaneously supporting development technique is ripe, and cost again can be not unattainable as ARM Cortex A9 dual core processor price of new generation.
Owing to need a large amount of patient's of storage blood glucose level data, normally according to the blood glucose level data storehouse, and be loaded with the diet database, memory space is bigger, so select popular on the market microSD card, promptly the mobile phone card is as the storage medium of storage unit 7.Simultaneously; Also store the blood sugar secure threshold that the patient doctor in charge sets in the said blood glucose level data storehouse; When patient's blood glucose value of measuring surpasses this threshold value; Processor 6 can be in display unit 8 display alarm information, and through sending alerting signal with alarm unit 9 and wireless transmission interface that processor 6 directly links to each other.
Preferably, the touch-screen of selecting to have control and input function can be made whole main frame and the similar volume of mobile phone size, to be convenient for carrying as display unit 8 like this.
When concrete the use; At first the patient is through display unit 8 input diet information; Comprise dietetic variety quantity, processor 6 receive this type of information after, call the data of the record of diet database in the storage unit 7; Can draw the sugar information of taking in through diet through calculating, comprise: the intake of the sugar of diet and time.Simultaneously, processor 6 obtains the electric signal of signal processing unit 5 transmission, changes into corresponding blood glucose value; And the blood glucose value of gained is presented on the display unit 8; A plurality of blood glucose values of the former period of individual blood glucose level data storehouse record in this blood glucose value and the storage unit 7 are interrelated, draw individual blood glucose curve, processor calls the blood glucose level data of corresponding period in the healthy blood glucose level data storehouse simultaneously; Drafting is with reference to blood glucose curve; With said blood glucose value, blood glucose curve and be presented on the display unit 8, the correlation parameter of each database in the updated stored unit 7 simultaneously with reference to blood glucose curve.
According to the intake and time of sugar of diet last time, draw one relatively with the blood glucose value that records through comparison, fixing voluntarily glycemic index; Value 1-100; 90-100 is a kilter, and this moment, the patient can not take any hypoglycemic measure, such as intravenous injection insulin etc.; 70-90 is for taking medicine state, and the patient gets final product according to the positive informal dress antidiabetic drug of doctor's advice.Be precarious position below 70, the prompting patient seeks medical advice immediately and sends information to family numbers of patients.
The above; Be merely the preferable embodiment of the utility model; But the protection domain of the utility model is not limited thereto; Any technician who is familiar with the present technique field is equal to replacement or changes according to the technical scheme of the utility model and utility model design thereof in the technical scope that the utility model discloses, and all should be encompassed within the protection domain of the utility model.

Claims (5)

1. a portable non-invasive blood sugar monitoring instrument is characterized in that having: saliva sugar concentration deriving means and processing host;
Said saliva sugar concentration deriving means has:
Be configured for gathering the sample collecting portion (1) of saliva sample by polyurethane foam;
Be filled with lactochrome adenylic acid complexing GDH, the saliva sample that is used to make sample collecting portion (1) to gather carries out the electrochemical reaction groove (2) of electrochemical reaction;
Be connected on the electrochemical reaction groove (2), be used for the electric signal transfer wire (3) of the conduction of current that produces in the electrochemical reaction groove (2) to the main frame;
Said sample collecting portion (1) is fixed on the electrochemical reaction groove (2);
Said electrochemical reaction groove (2) outside is provided with insulation course (201);
Said processing host comprises:
The physics and chemistry conversion of signals that said saliva sugar concentration deriving means is obtained is the signal processing unit (5) of electric signal;
Be pre-stored with the patient individual blood glucose level data storehouse that has the blood sugar secure threshold, the storage unit (7) of healthy blood glucose level data storehouse and diet database;
The display unit (8) that has control and input function; And
The electric signal of signal processing unit (5) conversion gained is changed into blood glucose value to be presented on the display unit (8); A plurality of blood glucose values of the former period of individual blood glucose level data storehouse record in this blood glucose value and the storage unit (7) are interrelated; Draw individual blood glucose curve; Processor calls the blood glucose level data of corresponding period in the healthy blood glucose level data storehouse simultaneously, draws with reference to blood glucose curve, with said blood glucose value; Blood glucose curve and be presented on the display unit (8), the processor (6) of the correlation parameter of each database in updated stored unit (7) simultaneously with reference to blood glucose curve.
2. portable non-invasive blood sugar monitoring instrument according to claim 1 is characterized in that the lactochrome adenylic acid complexing GDH of filling in the said electrochemical reaction groove (2) is wrapped on the glass nano microballoon.
3. portable non-invasive blood sugar monitoring instrument according to claim 1 and 2, the glass nano microballoon that it is characterized in that the lactochrome adenylic acid complexing GDH in the said electrochemical reaction groove (2) or be enclosed with lactochrome adenylic acid complexing GDH is dissolved in the phosphate-buffered saline damping fluid of pH value 7.4.
4. portable non-invasive blood sugar monitoring instrument according to claim 1 is characterized in that also comprising being used to monitor the threshold alerts unit (4) whether saliva that sample collecting portion (1) gathers reaches collection capacity; Said threshold alerts unit (4) comprising: be set in sample collecting portion (1) on every side, the humidity sensor (401) that the humidity of sample collecting portion (1) is detected;
Connect humidity sensor (401), the detected humidity value of humidity sensor (401) is compared with preset threshold, after humidity value reaches setting threshold, send the single-chip microcomputer (402) of alerting signal;
Connect single-chip microcomputer (402), the alerting signal that single-chip microcomputer (402) sends is carried out corresponding alarm unit (403);
Be connected on the loop that humidity sensor (401), single-chip microcomputer (402) and alarm unit (403) constitute, to the unlatching of circuit or close the switch of controlling (404).
5. portable non-invasive blood sugar monitoring instrument according to claim 1 is characterized in that also having: said processing host also has the wave point that links to each other with said processor (6).
CN2011202977272U 2011-08-16 2011-08-16 Portable non-invasive blood glucose monitor Withdrawn - After Issue CN202393731U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN2011202977272U CN202393731U (en) 2011-08-16 2011-08-16 Portable non-invasive blood glucose monitor

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN2011202977272U CN202393731U (en) 2011-08-16 2011-08-16 Portable non-invasive blood glucose monitor

Publications (1)

Publication Number Publication Date
CN202393731U true CN202393731U (en) 2012-08-22

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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102359984A (en) * 2011-08-16 2012-02-22 苏州悦安医疗电子有限公司 Portable noninvasive blood sugar monitor
CN103499621A (en) * 2013-10-22 2014-01-08 文加斌 Noninvasive blood glucose monitor
CN105615897A (en) * 2016-04-05 2016-06-01 京东方科技集团股份有限公司 Blood glucose monitoring device and blood glucose monitoring method
US20210183508A1 (en) * 2019-12-16 2021-06-17 Dexcom, Inc. Multi-state engagement with continuous glucose monitoring systems

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102359984A (en) * 2011-08-16 2012-02-22 苏州悦安医疗电子有限公司 Portable noninvasive blood sugar monitor
CN102359984B (en) * 2011-08-16 2013-10-09 苏州悦安医疗电子有限公司 Portable noninvasive blood sugar monitor
CN103499621A (en) * 2013-10-22 2014-01-08 文加斌 Noninvasive blood glucose monitor
CN105615897A (en) * 2016-04-05 2016-06-01 京东方科技集团股份有限公司 Blood glucose monitoring device and blood glucose monitoring method
WO2017173867A1 (en) * 2016-04-05 2017-10-12 京东方科技集团股份有限公司 Apparatus for monitoring blood glucose, and monitoring method therefor
CN105615897B (en) * 2016-04-05 2018-12-18 京东方科技集团股份有限公司 A kind of blood sugar monitor and its monitoring method
US20210183508A1 (en) * 2019-12-16 2021-06-17 Dexcom, Inc. Multi-state engagement with continuous glucose monitoring systems
US11696706B2 (en) * 2019-12-16 2023-07-11 Dexcom, Inc. Multi-state engagement with continuous glucose monitoring systems
US11712182B2 (en) 2019-12-16 2023-08-01 Dexcom, Inc. Multi-state engagement with continuous glucose monitoring systems

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C14 Grant of patent or utility model
GR01 Patent grant
AV01 Patent right actively abandoned

Granted publication date: 20120822

Effective date of abandoning: 20131009

RGAV Abandon patent right to avoid regrant