CN209474880U - A kind of oesophagus overlay film memory bracket suitable for treating without narrow or obstruction esophageal injury - Google Patents
A kind of oesophagus overlay film memory bracket suitable for treating without narrow or obstruction esophageal injury Download PDFInfo
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- CN209474880U CN209474880U CN201821433003.4U CN201821433003U CN209474880U CN 209474880 U CN209474880 U CN 209474880U CN 201821433003 U CN201821433003 U CN 201821433003U CN 209474880 U CN209474880 U CN 209474880U
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- oesophagus
- fixing end
- overlay film
- diaphragm
- rack body
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Abstract
The utility model relates to a kind of oesophagus overlay film memory brackets for treating without narrow or obstruction esophageal injury.The both ends of the bracket are respectively the first fixing end and the second fixing end, and centre is rack body;The rack body is woven by memory wire, is in cylindrical tube, outer diameter 40-50mm;Second fixing end is woven by memory wire, in horn-like;The entire outer wall of second fixing end and rack body coats film containing growth factor;First fixing end is made of several diaphragms with tension, and the lower edge of diaphragm is connected to the upper limb of rack body, these diaphragms round along the upper limb of rack body, and the diaphragm is in tight shape under use state.The utility model is provides a kind of new method without narrow or obstruction esophageal injury treatment, and the Esophageal Stent of the utility model can remarkably promote esophageal injury reparation, be not easy to shift, and be avoided that and cause new damage to oesophagus.
Description
Technical field
The utility model relates to the field of medical instrument technology, specifically, being related to a kind of suitable for treating without narrow or stalk
The oesophagus overlay film memory bracket of resistance but esophageal injury.
Background technique
Esophageal Stent is most common tool in various good pernicious esophagel disease treatments, and effect includes inner support, can be had
Effect releases thoracic choke, prevents the generation of lemostenosis, is conducive to feed nutrition, helps physical strength functional rehabilitation.Esophageal Stent is conventional
Patient's body certain time need to be retained in.These Esophageal Stents put universal principle, after bracket is put, because itself remembers
Expansive force makes the bracket clamp after expansion in stenosis, not easily shifted position.
And some has no obvious stenosis or obstruction patient, their oesophagus other parts are normal, and oesophagus only occurs
Oesophagus breakage caused by mucous membrane interruption and interior arthroscopic diagnosis is not repaired, it is often necessary to which open chest surgery, clinic lack effective food
Pipe holder is to help mucous membrane of esophagus reparation.
Generally speaking, at present clinically used Esophageal Stent be mostly release lemostenosis, obstruction and design, be not particularly suited for
Above-mentioned oesophagus is without narrow or obstruction patient.For this some patients, due to the similar bracket that not can be placed under scope, usually only
Energy surgical operation or conservative therapy, and these are treated, and the disease therapeuticing effect and life matter of patient are largely influenced
Amount.
Patent document CN201879873U, day for announcing 2011.06.29, to overcome conventional Recyclable Anti-reflux Esophageal Stents
Radial support power is small, the defects of granulation hyperplasia easily occur in both ends, and it is recyclable to provide a kind of super mouth of full overlay film of Ultimum Ti
Esophageal Stent, rack body both ends bulge, rack body are cylindrical body, and 40~160mm of total stent length is nickel-titanium shape memory
The reticular structure that alloy is woven into, bracket are integrally coated silica gel thin film, and the diameter of section of the rack body is 10~26mm, institute
The silica gel thin film stated forms skirt border structure beyond 5~10mm of collar extension of rack body upper end bulge.The Esophageal Stent is less prone to
The problems such as stent migration falls off, restenosis, bracket are difficult to take out, easy bleeding.
Patent document CN101984940A, publication date 2011.03.16, for solve traditional Esophageal Stent do not have prevention and
The problem for the treatment of esophageal fistula, disclose it is a kind of can load drug cover capsule Esophageal Stent, which is by inner support
Pipe and anther sac two parts composition, the inner support tube be bellows, bellows both ends respectively extend one have determine compared with Large Diameter Pipeline
Position is managed, and the bellows between two positioning pipes is active component, and the length of active component is greater than the length of diseased region;The anther sac
Cavity made of the one layer of elastomer seal wrapped up for the active component of bellows and its outside, on bellows active component
The drug-feeding tube communicated with anther sac is fixed at end pipe wall.The invention advantage is: bracket has certain axial bending benefit
In the placement of bracket, while again there is good radial strength can keep good channel, the bracket has better after powder charge
Elasticity, flexibility and good adhesion, can reduce damage of the bracket to diseased region, and it can be prevented to be subjected to displacement;It should
Bracket can also achieve the purpose that prevent and treat esophageal fistula, to mitigate the pain of patient.When selecting the bracket, it should make to prop up
The upper and lower mouth of frame exceeds narrow section (or diseased region) 10~20mm.
It can be seen that both the above Esophageal Stent is still all only applicable to the case where there are lemostenosis or obstructions, therefore
Oesophagus can effectively be treated without narrow or obstruction by needing one kind at present, but be occurred caused by mucous membrane of esophagus interruption or interior arthroscopic diagnosis
Oesophagus breakage such as does not repair at the new method or device of situations.
Summary of the invention
The purpose of this utility model is that aiming at the shortcomings in the prior art, oesophagus can effectively be treated without narrow by providing one kind
Or obstruction, but occur mucous membrane of esophagus interrupt or interior arthroscopic diagnosis caused by oesophagus breakage the oesophagus overlay film memories of situations such as do not repair
Bracket.
To achieve the above object, the technical scheme adopted by the utility model is that:
A kind of oesophagus overlay film memory bracket suitable for treating without narrow or obstruction esophageal injury, the oesophagus overlay film
Memory bracket both ends are respectively the first fixing end and the second fixing end, are branch between first fixing end and the second fixing end
Frame body;The rack body is woven by memory wire, is in cylindrical tube, outer diameter 40-50mm;Described second is solid
Fixed end is woven by memory wire, in horn-like;The entire outer wall cladding of second fixing end and rack body contains
Growth factor film;First fixing end is made of several diaphragms with tension, and the lower edge of diaphragm is connected to rack body
Upper limb, these diaphragms round along the upper limb of rack body, and the diaphragm is in tight shape under use state.
As a preference, the outer diameter of the second fixing end lower edge is 55-60mm.
As another preference, the memory wire of second fixing end and rack body is integrated.
As another preference, the diaphragm is half elliptic, semicircle or trapezoidal.
As another preference, the diaphragm lower edge be it is linear, be connected to the upper limb of rack body.
As another preference, the diaphragm thickness is 50-200nm.
As another preference, the diaphragm quantity is 4-10 piece.
As another preference, the rack body upper limb is waveform, several grooves is equipped with, under the diaphragm
Inserted type is corrected to be connected in groove.
As another preference, the diaphragm is ellipse, round or trapezoidal.
As another preference, the upper limb of the diaphragm exceeds the upper limb of rack body.
The present invention also provides another oesophagus overlay film memory bracket, it is equally applicable to treat without narrow or obstruction oesophagus
Damage, the oesophagus overlay film memory bracket both ends are respectively the first fixing end and the second fixing end, first fixing end
And second be rack body between fixing end;The rack body is woven by memory wire, is in cylindrical tube, outer diameter
40-50mm;Second fixing end is woven by memory wire, in horn-like;Second fixing end and bracket
The entire outer wall of main body is coated with film;First fixing end is made of several diaphragms with tension, and the lower edge of diaphragm connects
The upper limb in rack body is connect, these diaphragms round along the upper limb of rack body, and the diaphragm is under use state
Tight shape.
As a preference, the outer diameter of the second fixing end lower edge is 55-60mm.
As another preference, the memory wire of second fixing end and rack body is integrated.
As another preference, the diaphragm is half elliptic, semicircle or trapezoidal.
As another preference, the diaphragm lower edge be it is linear, be connected to the upper limb of rack body.
As another preference, the diaphragm thickness is 50-200nm.
As another preference, the diaphragm quantity is 4-10 piece.
As another preference, the rack body upper limb is waveform, several grooves is equipped with, under the diaphragm
Inserted type is corrected to be connected in groove.
As another preference, the diaphragm is ellipse, round or trapezoidal.
As another preference, the upper limb of the diaphragm exceeds the upper limb of rack body.
The utility model advantage is:
1, present inventor is based on clinical experience abundant, without narrow or obstruction but occurs in mucous membrane of esophagus for oesophagus
Oesophagus breakage caused by disconnected or interior arthroscopic diagnosis such as does not repair at the situations, proposes the new method of Esophageal Stent treatment, and be based on this
The oesophagus overlay film memory bracket of the utility model is devised, the main part outer diameter of the oesophagus overlay film memory bracket is larger, makes
The method for placing Esophageal Stent can also be used without narrow or obstruction esophageal injury treatment in oesophagus, effectively overcomes outside taking at present
The drawbacks of section's operation or conservative therapy.
2, the oesophagus overlay film memory bracket outer wall of the utility model is equipped with film containing growth factor, and growth factor is loaded into film
Portion can promote the reparation of mucous membrane with the sustained release growth factor, and can also be effectively isolated outside oesophagus and extraneous oesophagus and organize.
3, the upper end of the oesophagus overlay film memory bracket of the utility model is made of several diaphragms with tension, use state
Lower diaphragm is bonded in tight state and by expansion with mucous membrane of esophagus inner wall, is provided biggish frictional force, can be played fixed function,
Prevent stent migration from falling off;The especially whole tension from the bottom to top of diaphragm gradually reduces, therefore to the oesophagus at this position
Mucous membrane has gradually decreased expansionary force, plays good mucosa.
4, the lower end of the oesophagus overlay film memory bracket of the utility model is in horn-like, and diameter is greater than rack body, therefore can
To support oesophagus inner wall, Esophageal Stent is effectively prevent to shift.
Detailed description of the invention
Attached drawing 1 is the oesophagus overlay film memory bracket main view of embodiment 1 (under complete release conditions).
Attached drawing 2 is the oesophagus overlay film memory bracket main view of embodiment 1 (under limit state).
Attached drawing 3 is the oesophagus overlay film memory bracket main view of embodiment 2 (under complete release conditions).
Specific embodiment
It elaborates with reference to the accompanying drawing to specific embodiment provided by the utility model.
Appended drawing reference involved in attached drawing and component part are as follows:
1. 2. second fixing end of the first fixing end
3. 4. film containing growth factor of rack body
5. 6. groove of diaphragm
The oesophagus overlay film memory bracket (one) of 1 the utility model of embodiment
Referring to Figure 1, Fig. 1 is the oesophagus overlay film memory bracket main view of embodiment 1 (under complete release conditions).Described
The both ends of oesophagus overlay film memory bracket are respectively the first fixing end 1 and the second fixing end 2, first fixing end 1 and second
It is rack body 3 between fixing end 2.The rack body 3 is woven by memory wire, is in cylindrical tube, outer diameter 40-
50mm.Second fixing end 2 is also to be woven by memory wire, and in horn-like, the outer diameter of lower edge is 52-56mm.
The memory wire of second fixing end 2 and rack body 3 is integrated.Second fixing end 2 and bracket
The entire outer wall of main body 3 coats film containing growth factor 4.First fixing end 1 is made of several diaphragms 5;The film
Piece 5 have tension, be half elliptic, the lower edge of diaphragm 5 be it is linear, be connected to the upper limb of rack body 3;These 5 edges of diaphragm
The upper limb of rack body 3 round.
The oesophagus overlay film memory bracket application method of the utility model are as follows:
It is the oesophagus overlay film memory bracket main view of embodiment 1 referring first to Fig. 2, Fig. 2 (under limit state).It is being not used
Under state, the oesophagus overlay film memory bracket is defined in the catheter, the memory metal of the second fixing end 2 and rack body 3
Silk is elongated, and is radially become smaller, and the diaphragm 5 is gathered to center, and the film containing growth factor 4 is in buckle condition.
Again referring to Figure 1, without narrow or obstruction but occur caused by mucous membrane of esophagus interruption or interior arthroscopic diagnosis for oesophagus
Oesophagus breakage such as does not repair at the situations, and under scope, patient will be equipped with conduit merging patient's food of the oesophagus overlay film memory bracket
In pipe, when the mucous membrane of esophagus position that need to be repaired is placed exactly in the section of rack body 3, the oesophagus overlay film memory branch is discharged
Frame, the outer wall of film containing growth factor 4 fits in mucous membrane of esophagus inner wall at this time, the mucous membrane of esophagus that need to be repaired and film containing growth factor 4
Contact, second fixing end 2 strut oesophagus, and the diaphragm 5 is also flared because of the expansion of memory wire radial direction in tight
Taut shape.Then these diaphragms 5 are separately fixed on mucous membrane of esophagus under scope with clip by patient, make the outer wall and food of diaphragm 5
The inner wall of pipe mucous membrane is bonded.
It should be noted that the oesophagus overlay film memory bracket of the utility model is suitable for oesophagus without narrow or obstruction but occurs
The situation that oesophagus breakage caused by mucous membrane of esophagus interruption or interior arthroscopic diagnosis is not repaired, therefore the outer diameter of rack body 3 is 40-
50mm can guarantee that film containing growth factor 4 fits in mucous membrane of esophagus inner wall substantially, this is designed as oesophagus without narrow or obstruction patient
Mucous membrane of esophagus reparation provide a kind of practicable new method.The film containing growth factor 4 is any containing growth
The factor and can the sustained release growth factor membrane material, such as can be prepared according to method disclosed in patent document CN101168073A,
It can also be prepared according to any method of this specification embodiment 3-7.Growth factor is loaded into film by film containing growth factor 4
Portion can promote the reparation of mucous membrane with the sustained release growth factor, and can also be effectively isolated outside oesophagus and extraneous oesophagus and organize.Contain
Growth factor film 4 can be placed directly against the outer wall of the second fixing end 2 and rack body 3.First fixing end 1 is had by several
The diaphragm 5 of tension forms, and diaphragm 5 is bonded in tight state and by expansion with mucous membrane of esophagus inner wall under use state, provides larger
Frictional force, fixed function can be played, prevent the utility model oesophagus overlay film memory bracket shift fall off.Especially diaphragm
5 whole tension from the bottom to top gradually reduce, therefore have gradually decreased expansionary force to the mucous membrane of esophagus at the position, rise
To good mucosa.The preferred 50-200nm of 5 thickness of diaphragm, quantity can be 4-10 piece, and shape can also be semicircle
Shape, trapezoidal or lower edge are the shape that straight line upper limb is any curve.In horn-like, diameter is greater than second fixing end 2
Rack body 3, therefore oesophagus inner wall can be supported, it effectively prevent Esophageal Stent to shift.
The oesophagus overlay film memory bracket (two) of 2 the utility model of embodiment
Referring to figure 3., Fig. 3 is the oesophagus overlay film memory bracket main view of embodiment 2 (under complete release conditions).Described
The both ends of oesophagus overlay film memory bracket are respectively the first fixing end 1 and the second fixing end 2, first fixing end 1 and second
It is rack body 3 between fixing end 2.The rack body 3 is woven by memory wire, is in cylindrical tube, outer diameter 40-
50mm, the upper limb of rack body 3 are waveform, are equipped with several grooves 6.Second fixing end 2 is also by memory wire
It weaves, in horn-like, the outer diameter of lower edge is 52-56mm.The memory metal of second fixing end 2 and rack body 3
Silk is integrated.The entire outer wall of second fixing end 2 and rack body 3 coats film containing growth factor 4.Described
First fixing end 1 is made of several diaphragms 5;The diaphragm 5 has tension, and for ellipse, the lower end of diaphragm 5 is placed exactly in
In groove 6, the upper end of diaphragm 5 exceeds the upper limb certain altitude of rack body 3.These diaphragms 5 along rack body 3 upper limb ring
Around one week.
The diaphragm 5 of the embodiment is just connect with groove 6 in inserted type, in a state of use, corrected under diaphragm 5 by
The stronger stretching expansion of the upper limb of rack body 3, stronger with oesophagus inner wall frictional force, fixed effect is stronger.The diaphragm 5
It can also be round, trapezoidal or other shapes.
The Electrospun nano-fibers film (one) of the invention of embodiment 3
(a) prepare Electrospun solution: shell solution is with polylactic acid that hexafluoroisopropanol (being purchased from Merck) is solvent in oneself
Ester copolymer (75:25) solution, concentration 0.08g/mL, for sandwich layer solution using ultrapure water as solvent, solute is recombined human EGF albumen
(being purchased from Gibco, article No. PHG0315), protein concentration 20ng/ml;
(b) Dispersion relation: being 18-20 DEG C, humidity 45-50% in environment temperature, shell and sandwich layer solution are completely dissolved
After uniformly, shell solution and sandwich layer solution are injected separately into coaxial electrostatic spinning equipment, and (SS-2535, Beijing Yongkang are worked in peace and contentment science and technology
Development Co., Ltd) two syringes in, spinning voltage 15kV, spray head to receiving device distance be 15cm, control shell
Stablize flow velocity 0.015mL/h with sandwich layer, when voltage is more than critical value, sandwich layer and shell solution are sprayed onto from inside and outside on the top of spray head
End, forms that superfine solution fluid flies to receiver and to be cured as diameter rapidly below ultra-fine in micron under the action of electric field
Fiber receives to form drug containing nano fibrous membrane at receiving device.
The Electrospun nano-fibers film (two) of the invention of embodiment 4
(a) prepare Electrospun solution: shell solution is with polylactic acid that hexafluoroisopropanol (being purchased from Merck) is solvent in oneself
Ester copolymer (75:25) solution, concentration 0.10g/mL, for sandwich layer solution using ultrapure water as solvent, solute is recombined human EGF albumen
(being purchased from Gibco, article No. PHG0315), protein concentration 15ng/ml;
(b) Dispersion relation: being 18-20 DEG C, humidity 45-50% in environment temperature, shell and sandwich layer solution are completely dissolved
After uniformly, shell solution and sandwich layer solution are injected separately into coaxial electrostatic spinning equipment, and (SS-2535, Beijing Yongkang are worked in peace and contentment science and technology
Development Co., Ltd) two syringes in, spinning voltage 14kV, spray head to receiving device distance be 14cm, control shell
Stablize flow velocity 0.017mL/h with sandwich layer, when voltage is more than critical value, sandwich layer and shell solution are sprayed onto from inside and outside on the top of spray head
End, forms that superfine solution fluid flies to receiver and to be cured as diameter rapidly below ultra-fine in micron under the action of electric field
Fiber receives to form drug containing nano fibrous membrane at receiving device.
The Electrospun nano-fibers film (three) of the invention of embodiment 5
(a) prepare Electrospun solution: shell solution is with polylactic acid that hexafluoroisopropanol (being purchased from Merck) is solvent in oneself
Ester copolymer (75:25) solution, concentration 0.06g/mL, for sandwich layer solution using ultrapure water as solvent, solute is recombined human EGF albumen
(being purchased from Gibco, article No. PHG0315), protein concentration 15ng/ml;
(b) Dispersion relation: being 18-20 DEG C, humidity 45-50% in environment temperature, shell and sandwich layer solution are completely dissolved
After uniformly, shell solution and sandwich layer solution are injected separately into coaxial electrostatic spinning equipment, and (SS-2535, Beijing Yongkang are worked in peace and contentment science and technology
Development Co., Ltd) two syringes in, spinning voltage 16kV, spray head to receiving device distance be 14cm, control shell
Stablize flow velocity 0.015mL/h with sandwich layer, when voltage is more than critical value, sandwich layer and shell solution are sprayed onto from inside and outside on the top of spray head
End, forms that superfine solution fluid flies to receiver and to be cured as diameter rapidly below ultra-fine in micron under the action of electric field
Fiber receives to form drug containing nano fibrous membrane at receiving device.
The Electrospun nano-fibers film (four) of the invention of embodiment 6
(a) prepare Electrospun solution: shell solution is with polylactic acid that hexafluoroisopropanol (being purchased from Merck) is solvent in oneself
Ester copolymer (75:25) solution, concentration 0.10g/mL, for sandwich layer solution using ultrapure water as solvent, solute is recombined human EGF albumen
(being purchased from Gibco, article No. PHG0315), protein concentration 25ng/ml;
(b) Dispersion relation: being 18-20 DEG C, humidity 45-50% in environment temperature, shell and sandwich layer solution are completely dissolved
After uniformly, shell solution and sandwich layer solution are injected separately into coaxial electrostatic spinning equipment, and (SS-2535, Beijing Yongkang are worked in peace and contentment science and technology
Development Co., Ltd) two syringes in, spinning voltage 16kV, spray head to receiving device distance be 16cm, control shell
Stablize flow velocity 0.013mL/h with sandwich layer, when voltage is more than critical value, sandwich layer and shell solution are sprayed onto from inside and outside on the top of spray head
End, forms that superfine solution fluid flies to receiver and to be cured as diameter rapidly below ultra-fine in micron under the action of electric field
Fiber receives to form drug containing nano fibrous membrane at receiving device.
The Electrospun nano-fibers film (five) of the invention of embodiment 7
(a) prepare Electrospun solution: shell solution is with polylactic acid that hexafluoroisopropanol (being purchased from Merck) is solvent in oneself
Ester copolymer (75:25) solution, concentration 0.08g/mL, for sandwich layer solution using ultrapure water as solvent, solute is recombined human EGF albumen
(being purchased from Gibco, article No. PHG0315), protein concentration 20ng/ml;
(b) Dispersion relation: being 18-20 DEG C, humidity 45-50% in environment temperature, shell and sandwich layer solution are completely dissolved
After uniformly, shell solution and sandwich layer solution are injected separately into coaxial electrostatic spinning equipment, and (SS-2535, Beijing Yongkang are worked in peace and contentment science and technology
Development Co., Ltd) two syringes in, spinning voltage 15kV, spray head to receiving device distance be 15cm, control shell
Stablize flow velocity 0.017mL/h with sandwich layer, when voltage is more than critical value, sandwich layer and shell solution are sprayed onto from inside and outside on the top of spray head
End, forms that superfine solution fluid flies to receiver and to be cured as diameter rapidly below ultra-fine in micron under the action of electric field
Fiber receives to form drug containing nano fibrous membrane at receiving device.
The above is only the preferred embodiment of the utility model, it is noted that for the common skill of the art
Art personnel can also make several improvement and supplement under the premise of not departing from the utility model method, these are improved and supplement
Also it should be regarded as the protection scope of the utility model.
Claims (10)
1. a kind of oesophagus overlay film memory bracket suitable for treating without narrow or obstruction esophageal injury, which is characterized in that described
Oesophagus overlay film memory bracket both ends be respectively the first fixing end and the second fixing end, first fixing end and second fixed
It is rack body between end;The rack body is woven by memory wire, is in cylindrical tube, outer diameter 40-50mm;Institute
The second fixing end stated is woven by memory wire, in horn-like;Second fixing end and rack body it is entire
Outer wall coats film containing growth factor;First fixing end is made of several diaphragms with tension, the lower edge connection of diaphragm
In the upper limb of rack body, these diaphragms round along the upper limb of rack body, and the diaphragm is in tight under use state
Taut shape.
2. oesophagus overlay film memory bracket according to claim 1, which is characterized in that outside the lower edge of second fixing end
Diameter is 52-56mm.
3. oesophagus overlay film memory bracket according to claim 1, which is characterized in that second fixing end and bracket master
The memory wire of body is integrated.
4. oesophagus overlay film memory bracket according to claim 1, which is characterized in that the diaphragm is half elliptic, partly
It is round or trapezoidal.
5. oesophagus overlay film memory bracket according to claim 4, which is characterized in that the diaphragm lower edge be it is linear,
It is connected to the upper limb of rack body.
6. oesophagus overlay film memory bracket according to claim 1, which is characterized in that the diaphragm thickness is 50-
200nm。
7. oesophagus overlay film memory bracket according to claim 1, which is characterized in that the diaphragm quantity is 4-10 piece.
8. oesophagus overlay film memory bracket according to claim 1, which is characterized in that the rack body upper limb is wave
Shape is equipped with several grooves, corrects inserted type under the diaphragm and be connected in groove.
9. oesophagus overlay film memory bracket according to claim 8, which is characterized in that the diaphragm is ellipse, round
Or it is trapezoidal.
10. oesophagus overlay film memory bracket according to claim 8, which is characterized in that the upper limb of the diaphragm is beyond branch
The upper limb of frame body.
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CN201821433003.4U CN209474880U (en) | 2018-09-03 | 2018-09-03 | A kind of oesophagus overlay film memory bracket suitable for treating without narrow or obstruction esophageal injury |
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Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN111544170A (en) * | 2020-05-13 | 2020-08-18 | 东华大学 | Anti-slip narrow-resistance esophageal stent with mesoporous structure |
CN109172073B (en) * | 2018-09-03 | 2023-11-21 | 上海市第一人民医院 | Electrostatic spinning nanofiber membrane for controlling release of growth factors and esophageal tectorial membrane memory stent |
-
2018
- 2018-09-03 CN CN201821433003.4U patent/CN209474880U/en active Active
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN109172073B (en) * | 2018-09-03 | 2023-11-21 | 上海市第一人民医院 | Electrostatic spinning nanofiber membrane for controlling release of growth factors and esophageal tectorial membrane memory stent |
CN111544170A (en) * | 2020-05-13 | 2020-08-18 | 东华大学 | Anti-slip narrow-resistance esophageal stent with mesoporous structure |
CN111544170B (en) * | 2020-05-13 | 2021-12-10 | 东华大学 | Anti-slip narrow-resistance esophageal stent with mesoporous structure |
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