CN209286170U - A kind of high quality medicinal granule granulation device - Google Patents
A kind of high quality medicinal granule granulation device Download PDFInfo
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- CN209286170U CN209286170U CN201821092016.XU CN201821092016U CN209286170U CN 209286170 U CN209286170 U CN 209286170U CN 201821092016 U CN201821092016 U CN 201821092016U CN 209286170 U CN209286170 U CN 209286170U
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- granulation
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- medicinal granule
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Abstract
The utility model discloses a kind of high quality medicinal granule granulation devices, it includes granulation device and drying device, and granulation device is connected with drying device by conveying pipeline；The granulation device includes driving base and granulation case；The granulation case includes chassis, and cabinet is equipped with above chassis, and cabinet side is equipped with feed opening, is equipped with stirring top cap above cabinet；The drying device includes drying cylinder, and drying cylinder one end is connected with whirlwind blower, and the other end is connected with dehumidifier；Feeding inlet is equipped with above drying cylinder one end；The dehumidifier includes the dehumidification cylinder being connected to drying cylinder, and dehumidification cylinder is equipped with steam discharge sieve pore, and dehumidification cylinder is externally provided with pumping air duct；Described conveying pipeline one end is connected to feed opening, and the conveying pipeline other end is connected to feeding inlet.The utility model granulation and drying effect are preferable, and manufactured granule uniform particle sizes not only meet the requirement of wet granulation, also improve the efficiency that wet granulation prepares medicinal granule, improve the drug quality of manufactured granule.
Description
Technical field
The utility model relates to a kind of pharmaceutical process plant, especially a kind of high quality medicinal granule granulation device.
Background technique
Wet granulation is that adhesive is added in drug powder, and the gantry or cohesive action by adhesive are flocked on powder
The method of particle is prepared together.Particle made of wet process passes through moistened surface, has granular mass good, good appearance, wear-resisting
Property compared with the advantages that strong, compact property is good, be most widely used in medical industry.The pelletization of wet granulation is broadly divided into
Two parts, first is that medicinal powder and adhesive mixing make grain forming, second is that forming firm drying to the dry coalescence of shaped granule
Granule.Currently used wet granulation equipment be usually pass through air-flow or agitating paddle agitation medicinal powder move medicinal powder, and
Scraper or cutter is fixedly installed in one side wall in granulation storehouse, makes the bonding granulation that contacts with adhesive in medicinal powder motion process；But
Since conventional wet granulation equipment is usually from top to bottom spray adhesive water mist, and when stirring granulation at spray head
The adhesive of powder contacts is more, and the adhesive far from the powder contacts at spray head is less, causes the partial size of granule uneven；
And since scraper or cutter are fixed on granulation storehouse inner sidewall, need the medicinal powder by contacting adhesive in agitation
Scraper is touched in punching or cutter can be only achieved the effect of single-size agent partial size, but in actual production, due to medicinal powder and adhesive
The grain diameter formed after contact is different, and inertia and suffered gravity size are also different, act on the position on scraper or cutter
Also different, be difficult to achieve the purpose that uniformly to pelletize in stirring, process velocity is also relatively slow, at the same when using cabinet shake also compared with
Greatly, manufactured granule quality is bad.Currently used wet process system granulation drying equipment is benefit during granule is dry
Moisture is evaporated with to granule heating, achievees the purpose that dry, but since disposably dry granule is more, is easy to produce
Non-uniform problem is heated, leads to moisture evaporation not exclusively, and is difficult to since granule accumulation moisture is evaporated rear vapor
Discharge in time, vapor easily cooling are adsorbed again by granule, and drying effect is bad, causes drug quality poor.Therefore, existing
Wet granulation equipment in granulation, that there are granulation efficiencies is lower, granulating efficiency is poor, and manufactured granule partial size is uneven,
The second-rate problem of granula；It is poor that there are drying effects when dry, and granule is difficult to the problem of being completely dried, and leads to drying
Granular pesticide amount of substance afterwards is bad.
Utility model content
The purpose of the utility model is to provide a kind of high quality medicinal granule granulation devices.The utility model granulation
Preferable with drying effect, manufactured granule uniform particle sizes not only meet the requirement of wet granulation, also improve wet granulation system
The efficiency of standby medicinal granule improves the drug quality of manufactured granule.
The technical solution of the utility model includes: a kind of high quality medicinal granule granulation device, including granulation device and drying
Device, granulation device and drying device are connected by conveying pipeline；The granulation device includes driving base and granulation case；The drive
Engine-bed center is equipped with rotating electric machine, and granulation case is located above driving base and connect with rotating electric machine；The granulation luggage
Chassis is included, cabinet is equipped with above chassis, cabinet side is equipped with feed opening, stirring top cap is equipped with above cabinet, is set on stirring top cap
There is agitating paddle；The drying device includes drying cylinder, and drying cylinder one end is connected with whirlwind blower, and the other end is connected with dehumidifier；
The drying cylinder is column sky cylinder, is equipped with feeding inlet above drying cylinder one end；The dehumidifier includes removing of being connected to drying cylinder
Wet cylinder, dehumidification cylinder are equipped with steam discharge sieve pore, and dehumidification cylinder is externally provided with pumping air duct；Described conveying pipeline one end is connected to feed opening, defeated
The expects pipe other end is connected to feeding inlet.
In a kind of high quality medicinal granule granulation device above-mentioned, the driving base includes pedestal, and base center is set
There is infundibulate to place groove, the rotating electric machine is located in pedestal, and rotating electric machine rotary shaft is located at placement bottom portion of groove, case of pelletizing
It is located at and places in groove.
In a kind of high quality medicinal granule granulation device above-mentioned, the chassis includes positioning disk, is set above positioning disk
There is granulation to stir disk, granulation, which is stirred, is connected with drive shaft on disk, positioning disk and granulation stir disk and pass through driving axis connection；On the positioning disk
Equipped with rotary steering groove, granulation, which is stirred, is equipped with guide rod below disk, guide rod is located in rotary steering groove, and guide rod includes connecting rod,
Connecting rod one end is equipped with pulley.
In a kind of high quality medicinal granule granulation device above-mentioned, the granulation stirs disk center location equipped with water mist spraying head
A, water mist spraying head A are connected to the water-supply-pipe being located in drive shaft.
In a kind of high quality medicinal granule granulation device above-mentioned, the cabinet inner sidewall is equipped with spiral lamination.
In a kind of high quality medicinal granule granulation device above-mentioned, the stirring top cap includes lid, and agitating paddle is located at
Below lid, agitating paddle includes the rotation arbor connecting with lid, and rotation arbor lower end is equipped with stirring blade, and rotation arbor is set
There is water mist spraying head B；The stirring blade is equipped with stirring sieve pore.
In a kind of high quality medicinal granule granulation device above-mentioned, the whirlwind blower and drying cylinder junction are equipped with electricity
Heated filament.
In a kind of high quality medicinal granule granulation device above-mentioned, thread drum, screw thread rolling are equipped in the dehumidification cylinder
Cylinder surface is equipped with thread groove；The steam discharge sieve pore is located at dehumidification cylinder upper end, and steam discharge screen-aperture is less than granulation partial size.
In a kind of high quality medicinal granule granulation device above-mentioned, described pumping air duct one end dehumidification cylinder is fixedly connected,
It is evacuated the air duct other end and is equipped with opening, pumping air duct upper end is connect with extraction line.
In a kind of high quality medicinal granule granulation device above-mentioned, support leg is equipped with below drying cylinder, support leg passes through
Fixed ring is connect with drying cylinder.
Compared with prior art, the utility model has the advantage that
1, granulating efficiency is good, granule uniform particle sizes；By the way that powdered drug to be put into granulation case, using in driving base
Rotating electric machine drive drive shaft rotation, thus make granulation stir disc spins, by pelletize case in powdered drug raise, utilize simultaneously
The agitating paddle being located on stirring top cap stirs disk in the same direction with granulation or counter-rotating generates air-flow and further raises powdered drug, benefit
The powder contacts raised in misty adhesive and case of pelletizing are sprayed simultaneously with water mist spraying head A and water mist spraying head B, due to water mist spraying head
A and water mist spraying head B sprays misty adhesive from above and below simultaneously, mixes powdered drug with adhesive more uniform, greatly
Width improves granulation efficiency, and improves granule quality；By the way that spiral lamination is arranged in granulation punch-out equipment box inner wall, make powdery
Drug is stirred disk by granulation and agitating paddle rotates after raising in the shape of a spiral；By the way that stirring sieve pore is arranged on stirring blade, make mist
The granule for forming uniform particle sizes after adhesive and powdered drug mixing by stirring sieve pore, improves granulating efficiency.
2, granulation is stablized, and granulation efficiency is higher；By the way that guide groove is arranged on positioning disk, and stirs below disk and be arranged in granulation
Guide rod, stirring granulation, disk is more stable when rotating electric machine drives rotation, reduces the shaking that disc spins generation is stirred in granulation, work
It is more stable to make process.
3, drying efficiency is higher；By whirlwind blower air blast, make to generate cyclonic air flow in drying cylinder, in addition drying cylinder
Wet granulate agent be dried, granule is promoted after entering in drying cylinder by air-flow, carries out mobile drying, and whirlwind
Air-flow generates the effect that stirring is stirred to it, makes granule uniform drying, significantly reduces the dry required time.
4, granule is dry abundant；By whirlwind blower air blast, cyclonic air flow forms stream of hot air after electric-heating-wire-heating,
Two necessary factors (surface temperature and air-flow velocity) for meeting moisture evaporation accelerate moisture evaporation, while passing through whirlwind gas
Stream stirs granule stirring, and vapor can separate in time, and dry particle is avoided to adsorb vapor again.It is dehumidified by setting
Machine extracts the vapor in dehumidification cylinder out separation using pumping air duct in time, and granule is dry sufficiently, furthermore sets in dehumidification cylinder
Set thread drum, granule can be moved in the thread groove on thread drum surface by airflow function, increase it is mobile away from
From vapor being sufficiently discharged by pumping air duct in the process, further improve the drying effect of granule.
5, Granular pesticide amount of substance is improved；The utility model is dry using flow-type, and granule is pushed by air-flow, particle
Agent is stirred heating evaporation moisture drying by airflow stirring in drying cylinder, caused by avoiding granule excessively heated and uneven heating
Effective ingredient is lost, and effectively raises Granular pesticide amount of substance.
In conclusion the utility model granulation and drying effect are preferable, manufactured granule uniform particle sizes not only meet wet
The requirement of method granulation, also improves the efficiency that wet granulation prepares medicinal granule, improves the medicinal substances of manufactured granule
Amount.
Detailed description of the invention
Fig. 1 is the structural schematic diagram of the utility model；
Fig. 2 is the separated structure schematic diagram of granulation device；
Fig. 3 is the separated structure schematic diagram of drying device；
Fig. 4 is the structural schematic diagram of agitating paddle.
The label in accompanying drawing is: 1- conveying pipeline, 2- drives base, 3- rotating electric machine, the chassis 4-, 5- cabinet, 6- blanking
Mouthful, 7- stirring top cap, 8- agitating paddle, 9- drying cylinder, 10- whirlwind blower, 11- dehumidifier, 12- feeding inlet, 13- dehumidification cylinder, 14-
Steam discharge sieve pore, 15- are evacuated air duct, 16- pedestal, and 17- places groove, 18- positioning disk, and disk, 20- drive shaft, 21- are stirred in 19- granulation
Rotary steering groove, 22- guide rod, 23- water mist spraying head A, 24- rotate arbor, 25- stirring blade, 26- water mist spraying head B, 27- spiral shell
Line roller, 28- extraction line.
Specific embodiment
The utility model is further described with reference to the accompanying drawings and examples, but is not intended as to the utility model
The foundation of limitation.
Embodiment.A kind of high quality medicinal granule granulation device, as shown in Figures 1 to 4, including granulation device and drying
Device, granulation device and drying device are connected by conveying pipeline 1；The granulation device includes driving base 2 and granulation case；It is described
2 center of base is driven to be equipped with rotating electric machine 3, granulation case is located at 2 top of driving base and connect with rotating electric machine 3；The system
Grain case includes chassis 4, and cabinet 5 is equipped with above chassis 4, and 5 side of cabinet is equipped with feed opening 6, is equipped with stirring top cap 7 above cabinet 5,
Stirring top cap 7 is equipped with agitating paddle 8；The drying device includes drying cylinder 9, and 9 one end of drying cylinder is connected with whirlwind blower 10, separately
One end is connected with dehumidifier 11；The drying cylinder 9 is column sky cylinder, is equipped with feeding inlet 12 above 9 one end of drying cylinder；The dehumidifying
Machine 11 includes the dehumidification cylinder 13 being connected to drying cylinder 9, and dehumidification cylinder 13 is equipped with steam discharge sieve pore 14, and dehumidification cylinder 13 is externally provided with pumping wind
Cylinder 15；Described 1 one end of conveying pipeline is connected to feed opening 6, and 1 other end of conveying pipeline is connected to feeding inlet 12.
The driving base 2 includes pedestal 16, and 16 center of pedestal is equipped with infundibulate and places groove 17, the rotating electric machine 3
It is located in pedestal 16,3 rotary shaft of rotating electric machine, which is located at, places 17 bottom of groove, and granulation case, which is located at, to be placed in groove 17；The bottom
Disk 4 includes positioning disk 18, and granulation is equipped with above positioning disk 18 and stirs disk 19, granulation, which is stirred on disk 19, is connected with drive shaft 20, positioning disk
18 stir disk 19 with granulation is connect by drive shaft 20；The positioning disk 18 is equipped with rotary steering groove 21, and 19 lower section of disk is stirred in granulation
Equipped with guide rod 22, guide rod 22 is located in rotary steering groove 21, and guide rod 22 includes connecting rod, and connecting rod one end is equipped with pulley；Institute
It states granulation and stirs 19 center location of disk equipped with water mist spraying head A23, water mist spraying head A23 is connected to the water-supply-pipe being located in drive shaft 20；
5 inner sidewall of cabinet is equipped with spiral lamination；The stirring top cap 7 includes lid, and agitating paddle 8 is located at below lid, agitating paddle 8
Including the rotation arbor 24 being connect with lid, rotates 24 lower end of arbor and be equipped with stirring blade 25, rotation arbor 24 is equipped with water mist
Spray head B26；The stirring blade 25 is equipped with stirring sieve pore；The whirlwind blower 10 is equipped with heating wire with 9 junction of drying cylinder；Institute
It states and is equipped with thread drum 27 in dehumidification cylinder 13,27 surface of thread drum is equipped with thread groove；The steam discharge sieve pore 14 is located at dehumidifying
13 upper ends of cylinder, 14 aperture of steam discharge sieve pore are less than granulation partial size；15 one end dehumidification cylinder 13 of pumping air duct is fixedly connected, pumping
15 other end of air duct is equipped with opening, and pumping 15 upper end of air duct is connect with extraction line 28；Support leg is equipped with below drying cylinder 9,
Support leg is connect by fixed ring with drying cylinder 9.
Working principle: when wet granulation, powdered drug is put into granulation case, utilizes the rotating electric machine 3 in driving base 2
It drives drive shaft 20 to rotate, so that granulation be made to stir the rotation of disk 19, the powdered drug pelletized in case is raised, while being stirred using being located at
It mixes that agitating paddle 8 on top cover 7 stirs disk 19 in the same direction with granulation or counter-rotating generates air-flow and further raises powdered drug, utilizes
Water mist spraying head A23 and water mist spraying head B26 sprays the powder contacts raised in misty adhesive and granulation case simultaneously, since water mist sprays
Head A23 and water mist spraying head B26 sprays misty adhesive from above and below simultaneously, mixes powdered drug with adhesive more equal
It is even；By granulation 5 inner sidewall of punch-out equipment case on spiral lamination is set, make powdered drug by granulation stir disk 19 and agitating paddle 8 rotation raise
After rising in the shape of a spiral；By the way that stirring sieve pore is arranged on stirring blade 25, pass through after mixing misty adhesive and powdered drug
The granule that sieve pore forms uniform particle sizes is stirred, by the way that guide groove is arranged on positioning disk 18, and stirs below disk 19 and sets in granulation
Set guide rod 22, make granulation stir disk 19 rotating electric machine 3 drive rotate when it is more stable, reduce granulation stir disk 19 rotation generate
Shaking, the course of work is more stable.
When discharging, feed opening 6 is opened, using the centripetal force centrifugal force of manufactured granule when rotated, is passing through blanking
Discharge granulation case when mouth 6, manufactured granule are put into drying cylinder 9 by conveying pipeline 1 through feeding inlet 12, and granule enters drying
After in cylinder 9, the whirlwind effect stirring generated by 10 air blast of whirlwind blower is stirred, and the cyclonic air flow that whirlwind blower 10 generates is through electric heating
Stream of hot air is formed after silk heating, meets the two necessary factor surface temperatures and air-flow velocity of moisture evaporation, accelerates moisture
Evaporation, vapor can separate in time, and by the way that dehumidifier 11 is arranged, extraction line 28 is connect with pumping blower, pumping air duct 15
The air-breathing that is open generates negative pressure gas flow, makes the vapor in dehumidification cylinder 13 through the extraction separation in time of steam discharge sieve pore 14, granule is dry
Sufficiently, thread drum 27 is set in dehumidification cylinder 13, granule can screw thread by airflow function on 27 surface of thread drum it is recessed
It is moved in slot, increases mobile distance, vapor can be sufficiently discharged by pumping air duct 15, further be mentioned in the process
The high drying effect of granule.
Claims (10)
1. a kind of high quality medicinal granule granulation device, it is characterised in that: including granulation device and drying device, granulation device
It is connected with drying device by conveying pipeline (1)；The granulation device includes driving base (2) and granulation case；The driving base
(2) center is equipped with rotating electric machine (3), and granulation case is located above driving base (2) and connect with rotating electric machine (3)；The system
Grain case includes chassis (4), is equipped with cabinet (5) above chassis (4), and cabinet (5) side is equipped with feed opening (6), is set above cabinet (5)
Have stirring top cap (7), stirring top cap (7) is equipped with agitating paddle (8)；The drying device includes drying cylinder (9), drying cylinder (9)
One end is connected with whirlwind blower (10), and the other end is connected with dehumidifier (11)；The drying cylinder (9) is column sky cylinder, drying cylinder
(9) feeding inlet (12) are equipped with above one end；The dehumidifier (11) includes the dehumidification cylinder (13) being connected to drying cylinder (9), dehumidifying
Cylinder (13) is equipped with steam discharge sieve pore (14), and dehumidification cylinder (13) is externally provided with pumping air duct (15)；Described conveying pipeline (1) one end and blanking
Mouth (6) connection, conveying pipeline (1) other end are connected to feeding inlet (12).
2. a kind of high quality medicinal granule granulation device according to claim 1, it is characterised in that: the driving base
It (2) include pedestal (16), pedestal (16) center is equipped with infundibulate and places groove (17), and the rotating electric machine (3) is located at pedestal
(16) in, rotating electric machine (3) rotary shaft, which is located at, places groove (17) bottom, and granulation case, which is located at, to be placed in groove (17).
3. a kind of high quality medicinal granule granulation device according to claim 1, it is characterised in that: the chassis (4)
Granulation being equipped with including positioning disk (18), above positioning disk (18) to stir disk (19), granulation, which is stirred on disk (19), is connected with drive shaft (20),
Positioning disk (18) stirs disk (19) with granulation and is connect by drive shaft (20)；The positioning disk (18) is equipped with rotary steering groove
(21), granulation stirs below disk (19) and is equipped with guide rod (22), and guide rod (22) is located in rotary steering groove (21), guide rod (22)
Including connecting rod, connecting rod one end is equipped with pulley.
4. a kind of high quality medicinal granule granulation device according to claim 3, it is characterised in that: disk is stirred in the granulation
(19) center location is equipped with water mist spraying head A(23), water mist spraying head A(23) it is connected to the water-supply-pipe being located in drive shaft (20).
5. a kind of high quality medicinal granule granulation device according to claim 1, it is characterised in that: the cabinet (5)
Inner sidewall is equipped with spiral lamination.
6. a kind of high quality medicinal granule granulation device according to claim 1, it is characterised in that: the stirring top cap
It (7) include lid, agitating paddle (8) is located at below lid, and agitating paddle (8) includes the rotation arbor (24) connecting with lid, rotation
Arbor (24) lower end is equipped with stirring blade (25), and rotation arbor (24) is equipped with water mist spraying head B(26)；The stirring blade (25)
Equipped with stirring sieve pore.
7. a kind of high quality medicinal granule granulation device according to claim 1, it is characterised in that: the whirlwind blower
(10) heating wire is equipped with drying cylinder (9) junction.
8. a kind of high quality medicinal granule granulation device according to claim 1, it is characterised in that: the dehumidification cylinder
(13) thread drum (27) are equipped in, thread drum (27) surface is equipped with thread groove；The steam discharge sieve pore (14) is located at dehumidifying
Cylinder (13) upper end, steam discharge sieve pore (14) aperture are less than granulation partial size.
9. a kind of high quality medicinal granule granulation device according to claim 1, it is characterised in that: the pumping air duct
(15) one end dehumidification cylinder (13) is fixedly connected, and pumping air duct (15) other end is equipped with opening, is evacuated air duct (15) upper end and is taken out
Steam pipe road (28) connection.
10. a kind of high quality medicinal granule granulation device according to claim 1, it is characterised in that: under drying cylinder (9)
Side is equipped with support leg, and support leg is connect by fixed ring with drying cylinder (9).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201821092016.XU CN209286170U (en) | 2018-07-11 | 2018-07-11 | A kind of high quality medicinal granule granulation device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201821092016.XU CN209286170U (en) | 2018-07-11 | 2018-07-11 | A kind of high quality medicinal granule granulation device |
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| Publication Number | Publication Date |
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| CN209286170U true CN209286170U (en) | 2019-08-23 |
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ID=67651529
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| Application Number | Title | Priority Date | Filing Date |
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| CN201821092016.XU Active CN209286170U (en) | 2018-07-11 | 2018-07-11 | A kind of high quality medicinal granule granulation device |
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| Country | Link |
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| CN (1) | CN209286170U (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111606740A (en) * | 2020-06-16 | 2020-09-01 | 民乐县锦世建材新材料有限责任公司 | Industrial production method of drying-free calcium superphosphate granulation |
-
2018
- 2018-07-11 CN CN201821092016.XU patent/CN209286170U/en active Active
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111606740A (en) * | 2020-06-16 | 2020-09-01 | 民乐县锦世建材新材料有限责任公司 | Industrial production method of drying-free calcium superphosphate granulation |
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