CN209034981U - Cleaning device and pumping equipment - Google Patents
Cleaning device and pumping equipment Download PDFInfo
- Publication number
- CN209034981U CN209034981U CN201821202148.3U CN201821202148U CN209034981U CN 209034981 U CN209034981 U CN 209034981U CN 201821202148 U CN201821202148 U CN 201821202148U CN 209034981 U CN209034981 U CN 209034981U
- Authority
- CN
- China
- Prior art keywords
- drain
- needle
- solenoid valve
- pump
- opening
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Landscapes
- Water Treatment By Electricity Or Magnetism (AREA)
Abstract
This application discloses a kind of cleaning device and pumping equipment, which includes drain unit, with the waste liquid for being discharged in reaction vessel.The drain unit includes drain needle, for extracting waste liquid；Draw-off pump is connected, to provide extraction power for the drain needle with the drain needle by drain line；Isolation ward is arranged in the drain line between the drain needle and the draw-off pump, adjusts the extraction power for being supplied to the drain needle to cooperate with the draw-off pump.By the above-mentioned means, the application, which can simply and easily buffer adjusting, twitches power, lower magnetic bead loss late, and fluid path device convenient for safeguarding can be obtained.
Description
Technical field
This application involves fluid path technical fields, more particularly to a kind of cleaning device and pumping equipment.
Background technique
Immuno magnetic cell separation technology is combine immunologic high degree of specificity with the distinctive magnetic responsiveness of magnetic bead one
Kind new isolation technics is the immunological detection method and antigen purification means of a kind of high specificity, high sensitivity, this technology
Cell separation, Protein Detection, immunology detection and in terms of be used widely.
To separate object of the non-targeted object of free state in conjunction with magnetic bead, need to carry out reactant in magnetic field
Magneto separate and cleaning, cleaning process are then to refill cleaning solution, such as by supernatant waste liquid in abstraction reaction cup in magnetic field
This iterative cycles is completed, and is needed in cleaning process that by the loss late control of target magnetic bead, in a certain range, foot could be provided
The more than enough compound for meeting detection demand.During extracting supernatant waste liquid, it is typically due to negative pressure and crosses conference to take away target magnetic bead, shadow
Ring last test process.Extracting supernatant waste liquid at present, usually there are two types of modes: first is that controlling vacuum magnitude with syringe, passing through row
Supernatant waste liquid is drawn in corresponding sewer pipe by liquid needle；Second is that supernatant is directly evacuated to waste liquid pool with peristaltic pump connected drainage needle
In.
Present inventor has found that it is multiple that the first scheme control negative pressure sucts clear liquid process in long-term R&D process
It is miscellaneous, increase component mobile space；The pipe of second scheme peristaltic pump needs to be replaced frequently, and is unfavorable for safeguarding, influences user
Experience.
Utility model content
The application can simply and easily delay mainly solving the technical problems that provide a kind of cleaning device and pumping equipment
It reconstitutes section and twitches power, the magnetic bead loss late of attenuating, and fluid path device convenient for safeguarding can be obtained.
In order to solve the above technical problems, the technical solution that the application uses is: providing a kind of cleaning device, comprising:
Drain unit comprising: for extracting the drain needle of waste liquid；Draw-off pump is connected by drain line with the drain needle, from
And extraction power is provided for the drain needle；The drain line between the drain needle and the draw-off pump is arranged in isolation ward
On, the extraction power for being supplied to the drain needle is adjusted to cooperate with the draw-off pump.
In order to solve the above technical problems, another technical solution that the application uses is: pumping equipment, comprising: drain needle,
For extracting waste liquid；Draw-off pump is connected by drain line with the drain needle, dynamic to provide extraction for the drain needle
Power；Isolation ward is arranged in the drain line between the drain needle and the draw-off pump, is adjusted with cooperating with the draw-off pump
Section is supplied to the extraction power of the drain needle.
The beneficial effect of the application is: being in contrast to the prior art, above-mentioned cleaning device, pumping equipment can use
Isolation ward carries out buffering adjusting to negative pressure extracting power, so that the extraction force control of drain needle is in a certain range, with effectively
The generation for accidentally extracting target magnetic bead phenomenon is avoided, to guarantee that magnetic bead loss late meets performance test demand；Relative to wriggling
The power source as negative pressure extracting power is pumped, is facilitated simultaneously more preferably using diaphragm pump without often replacement pipeline, longer life expectancy
It goes to safeguard；It uses plunger pump as the input power source of cleaning solution, the cleaning solution in injection reaction cup can be accomplished accurately to control,
Plunger pump compact simultaneously is conducive to instrument and realizes modularization management.
Detailed description of the invention
In order to more clearly explain the technical solutions in the embodiments of the present application, make required in being described below to embodiment
Attached drawing is briefly described, it should be apparent that, the drawings in the following description are only some examples of the present application, for
For those of ordinary skill in the art, without creative efforts, it can also be obtained according to these attached drawings other
Attached drawing.Wherein:
Fig. 1 is the structural schematic diagram of one embodiment of the application pumping equipment；
Fig. 2 is the structural schematic diagram of one embodiment of the application cleaning device；
Fig. 3 is the flow diagram of one embodiment of the application cleaning method.
Specific embodiment
Below in conjunction with the attached drawing in the embodiment of the present application, technical solutions in the embodiments of the present application carries out clear, complete
Site preparation description, it is clear that described embodiments are only a part of embodiments of the present application, rather than whole embodiments.Based on this
Embodiment in application, those of ordinary skill in the art are obtained every other under the premise of not making creative labor
Embodiment shall fall in the protection scope of this application.
Refering to fig. 1, Fig. 1 is the structural schematic diagram of one embodiment of the application pumping equipment, and pumping equipment 100 is for being discharged
Waste liquid in reaction vessel, for example, for carrying out institute in Magneto separate and cleaning process to reactant in immuno magnetic cell separation technology
The supernatant in reaction cup used, pumping equipment 100 include drain needle 110, draw-off pump 120 and isolation ward 130.
In the present embodiment, pumping equipment 100 can be an independent fluid path device, be also possible to some equipment
In fluid path unit, such as can be a fluid path unit of the cleaning device in cellanalyzer, can be filled with cleaning
Other fluid path units in setting, such as cleaning unit for injecting cleaning solution are used cooperatively, to complete entire cleaning process.
Specifically, the drain needle 110 in pumping equipment 100 is for being inserted into reaction vessel in abstraction reaction container
Waste liquid, such as the supernatant in reaction cup.Draw-off pump 120 is connected by drain line 140 with drain needle 110, to be
Drain needle 110, which provides, extracts power, such as the extraction power of negative pressure.And isolation ward 130 is arranged in drain needle 110 and draw-off pump
In drain line 140 between 120, moved with cooperating with draw-off pump 120 to adjust and buffer the extraction for being supplied to drain needle 110
Power.
In the present embodiment, draw-off pump 120 can not need to be replaced as frequently as using diaphragm pump relative to peristaltic pump
Relevant pipeline, longer life expectancy help more preferably to go to safeguard simultaneously.The concrete structure design of drain line 140 can be according to reality
Using and determine, it is not limited here.Isolation ward 130 and diaphragm pump 120 are arranged in drain line 140, and isolation ward 130
It is connected with diaphragm pump 120, in this way when diaphragm pump 120 adjusts the extraction power of negative pressure, isolation ward 130 can play buffering negative pressure
Extract the effect of power.Diaphragm pump 120 can claim control to pump again, can receive the control of adjuster or computer in control process
Signal processed changes the flow of fluid, maintains adjusting parameter (for example, duty cycle parameters) in required range, to reach
To the automation of production process.
In addition, pumping equipment 100 may further include the first solenoid valve 150, such as two-bit triplet solenoid valve, inside set
It is equipped with closed chamber, is provided with through-hole in different location, it is piston among chamber that each hole, which connects different accesses, and two sides is two pieces
Which side the magnet coil energization valve body of electromagnet, which face will be attracted to, therefore, can by the movement of application valve body come
Open or close different through-holes.That is, two-bit triplet solenoid valve is twin coil control, closed after a coil moment energization
Power supply is closed, valve is opened, and corresponding access communicates with each other；Another coil moment closes power supply after being powered, and valve is closed, corresponding logical
Road communicates with each other.Two-bit triplet solenoid valve can remain turned-off for a long time or opening state, coil life can be made longer, in high temperature
Using best in pipeline.
In the present embodiment, as shown in Figure 1, isolation ward 130 is provided with the first opening 131, second opening 132 and third is opened
Mouth 133, wherein the sidewall upper of isolation ward 130 is arranged in the first opening 131, and isolation ward 130 is arranged in the second opening 132
Side wall lower ends, and the top of isolation ward 130 is arranged in third opening 133.The normally open end 150A of first solenoid valve 150 passes through drain
Pipeline 140 and be connected to isolation ward 130 first opening 131, the normal-closed end 150B of the first solenoid valve 150 passes through drain line
140 and be connected to isolation ward 130 second opening 132, the working end 150C of the first solenoid valve 150 passes through drain line 140
It is connected to draw-off pump 120；And the third opening 133 of isolation ward 130 is connected to drain needle 110 by drain line 140.
In the present embodiment, diaphragm pump 120 can cooperate with the first solenoid valve 150, be input to pumping equipment to adjust
Negative pressure draft in 100, when the first solenoid valve 150 switches in normally open end 150A and opens, diaphragm pump 120 and isolation ward 130
First opening 131 be connected to be supplied to drain needle 110 normal work extraction forces, with the supernatant in abstraction reaction cup；
And when the first solenoid valve 150 switches in normal-closed end 150B and opens, the second 132 phases of opening of diaphragm pump 120 and isolation ward 130
Even, then the waste liquid accumulated in isolation ward 130 can be extracted.In entire discharge opeing process, isolation ward 130 can be to being input to drain
Negative pressure extracting power in device 100 plays the role of buffering and adjusts, so that the extraction force in drain needle 110 be made to be unlikely to too
By force, while avoiding supernatant of the drain needle 110 in abstraction reaction cup, the target magnetic bead in reaction cup has been extracted together.
In addition, waste liquid barrel 160 is arranged in drain pipe as shown in Figure 1, pumping equipment 100 still further comprises waste liquid barrel 160
The end on road 140 is connect by drain line 140 with diaphragm pump 120.Therefore, pumping equipment 100 extracts the waste liquid of discharge
It can be injected into waste liquid barrel 160 by relevant access.
It is the structural schematic diagram of one embodiment of the application cleaning device please continue to refer to Fig. 2, Fig. 2.As shown in Fig. 2, this
The cleaning device 200 of embodiment includes drain unit 210 and cleaning unit 220.
Wherein, it will be appreciated by persons skilled in the art that drain unit 210 in present embodiment with it is shown in FIG. 1
Pumping equipment 100 is similar, also includes drain needle 211, draw-off pump 212, isolation ward 213, the first solenoid valve 214, waste liquid barrel 215
And the drain line 216 of the above-mentioned each element of connection.Each element and pumping equipment 100 shown in FIG. 1 in drain unit 210
It is similar, therefore details are not described herein.
Cleaning unit 220 is for providing new cleaning solution for reaction vessel.That is, when utilizing above-mentioned drain unit
It can be further that injection is new in reaction vessel using cleaning unit 220 after 210 have been discharged the waste liquid in reaction vessel (supernatant)
Cleaning solution, again to be cleaned to the object (e.g., target magnetic bead) in reaction vessel, after cleaning again utilize drain
Relevant waste liquid is discharged in unit 210, to achieve the purpose that object is cleaned multiple times.
Specifically, cleaning unit 220 includes cleaning solution power supply unit 221, injection needle 222, plunger pump 223.Wherein, cleaning solution
Power supply unit 221 is for accommodating and supplying cleaning solution；Injection needle 222 is connected by fluid injection pipeline 225 and cleaning solution power supply unit 221
It connects, to obtain cleaning solution from cleaning solution power supply unit 221, and provides cleaning solution into reaction vessel；The setting of plunger pump 223 is being infused
It is connected on liquid pipeline 225 and with cleaning solution power supply unit 221 and injection needle 222, it will be in cleaning solution power supply unit 221 to provide power source
Cleaning solution be delivered in injection needle 222.
In addition, cleaning unit 220 can further comprise second solenoid valve 224, for example, two-position three way magnetic valve.Wherein, second
The working end of solenoid valve 224 is connected with plunger pump 223, and the normally open end of second solenoid valve 224 is connected with fluid injection pipeline 225, and the
The normal-closed end of two solenoid valves 224 is connected with cleaning solution power supply unit 221.Therefore, second solenoid valve 224 and plunger pump 223 cooperate, with
The cleaning solution in cleaning solution power supply unit 221 is delivered in injection needle 222 using plunger pump 223 according to demand.
In addition, as shown in Fig. 2, in the present embodiment, the drain needle 211 in drain unit 210 may include setting side by side
The minute hand 2111 and hour hand 2112 set, wherein minute hand 2111 is connected to isolation ward 213 and draw-off pump by drain line 216
212 to extract waste liquid, that is, realize the function of drain.And hour hand 2112 close to minute hand 2111 be arranged, and with infused in cleaning unit 220
Liquid pipeline 225 is connected, to obtain cleaning solution from cleaning unit 220 to carry out outer wall washing to minute hand 2111.
Specifically, in present embodiment, cleaning unit 220 can further comprise third solenoid valve 226, be arranged second
In fluid injection pipeline 225 between solenoid valve 224 and injection needle 222.Third solenoid valve 226 can use two-bit triplet solenoid valve,
The working end of third solenoid valve 226 is connected with fluid injection pipeline 225, and the normally open end of third solenoid valve 226 is connected with injection needle 222,
And the normal-closed end of third solenoid valve 226 is connected with hour hand 2112.That is, can be controlled by third solenoid valve 226 clear
Washing lotion is to be injected into injection needle 222, and to add cleaning solution to reaction cup, or control cleaning solution injects hour hand 2112, thus right
Minute hand 2111 carries out outer wall washing.
It is the flow diagram of one embodiment of the application cleaning method referring to Fig. 3, Fig. 3, this method is suitable for such as figure 2 above
The detailed description of the cleaning device, related content refers to above-mentioned cleaning device, no longer superfluous herein to chat.This method packet
It includes:
Step S101: reaction vessel is placed under drain needle 211, and is controlled drain needle 211 and be displaced downwardly to the reaction
At the suitable position of container.
Step S102: opening diaphragm pump 212, the duty cycle parameters of diaphragm pump 212 is adjusted, so that the supernatant in reaction vessel
Liquid is discharged by drain needle 211, isolation ward 213 and diaphragm pump 212, and further drains into waste liquid barrel 215.
Step S103: the first solenoid valve 214 of switching is to normal-closed end, and full-load run separate pump 212 is with will be in isolation ward 213
Residual liquid evacuates；
Step S104: rotational response container to 222 lower section of injection needle, opening plunger pump 223, by cleaning solution power supply unit
Cleaning solution in 221 injects reaction vessel by injection needle 222.
Step S105: rotational response container to 211 lower section of drain needle, repeats the above steps, to complete pre-determined number again
Cleaning and discharge opeing process.
Step S106: after the completion of pre-determined number cleaning, opening plunger pumps 223, diaphragm pump 212, third solenoid valve 226, with
Complete the cleaning to drain needle 211.
In conclusion by above-mentioned cleaning device and pumping equipment, 1) can use isolation ward to negative pressure extracting power into
Row buffering is adjusted, so that the extraction force control of drain needle is in a certain range, accidentally extracts target magnetic bead phenomenon to be effectively prevented from
Generation, to guarantee that magnetic bead loss late meets performance test demand；2) relative to use peristaltic pump as negative pressure extracting power
Power source helps more preferably to go to safeguard simultaneously using diaphragm pump without often replacement pipeline, longer life expectancy；3) use plunger pump as
The input power source of cleaning solution can accomplish accurately to control to the cleaning solution in injection reaction cup, while plunger pump compact,
Be conducive to instrument and realize modularization management.
The foregoing is merely presently filed embodiments, are not intended to limit the scope of the patents of the application, all to utilize this
Equivalent structure or equivalent flow shift made by application specification and accompanying drawing content, it is relevant to be applied directly or indirectly in other
Technical field similarly includes in the scope of patent protection of the application.
Claims (10)
1. a kind of cleaning device characterized by comprising
Drain unit comprising:
For extracting the drain needle of waste liquid；
Draw-off pump is connected, to provide extraction power for the drain needle with the drain needle by drain line；
Isolation ward is arranged in the drain line between the drain needle and the draw-off pump, to cooperate with the draw-off pump
Adjust the extraction power for being supplied to the drain needle.
2. cleaning device according to claim 1, which is characterized in that the draw-off pump is diaphragm pump.
3. cleaning device according to claim 2, which is characterized in that the drain unit further comprises:
First solenoid valve is arranged in the drain line between the isolation ward and the diaphragm pump.
4. cleaning device according to claim 3, which is characterized in that first solenoid valve is two-position three way magnetic valve,
And the isolation ward is provided with the first opening, the second opening and third opening, wherein first opening is arranged in the isolation
The sidewall upper of room, the side wall lower ends of the isolation ward are arranged in second opening, and third opening is arranged described
The top of isolation ward, the normally open end of first solenoid valve are connected to the first opening of the isolation ward by drain line,
The normal-closed end of first solenoid valve is connected to the second opening of the isolation ward, first solenoid valve by drain line
Working end the draw-off pump is connected to by drain line；And the third opening of the isolation ward passes through drain line company
It is connected to the drain needle.
5. cleaning device according to claim 1, which is characterized in that further comprise:
Cleaning unit comprising:
For accommodating and providing the cleaning solution power supply unit of cleaning solution；
Injection needle is connect, to be cleaned from the cleaning solution power supply unit with the cleaning solution power supply unit by fluid injection pipeline
Liquid, and cleaning solution is provided into reaction vessel；
Plunger pump is arranged on the liquid injection pipe road and is connected with the cleaning solution power supply unit and the injection needle, dynamic to provide
Cleaning solution in the cleaning solution power supply unit is delivered in the injection needle by power source.
6. cleaning device according to claim 5, which is characterized in that the cleaning unit further comprises:
Second solenoid valve, wherein the working end of the second solenoid valve is connected with the plunger pump, the second solenoid valve it is normal
Beginning is connected with the fluid injection pipeline, and the normal-closed end of the second solenoid valve is connected with the cleaning solution power supply unit.
7. cleaning device according to claim 6, which is characterized in that the drain needle includes minute hand arranged side by side and short
Needle, wherein the minute hand is connected to the isolation ward and the draw-off pump as main drain needle, by drain line to extract
Waste liquid；And the hour hand is connected to obtain cleaning solution to the minute hand and clean with the fluid injection pipeline.
8. cleaning device according to claim 7, which is characterized in that the cleaning unit further comprises:
Third solenoid valve, wherein the working end of the third solenoid valve is connected with the fluid injection pipeline, the third solenoid valve
Normally open end is connected with the injection needle, and the normal-closed end of the third solenoid valve is connected with the hour hand.
9. a kind of pumping equipment characterized by comprising
Drain needle, for extracting waste liquid；
Draw-off pump is connected, to provide extraction power for the drain needle with the drain needle by drain line；
Isolation ward is arranged in the drain line between the drain needle and the draw-off pump, to cooperate with the draw-off pump
Adjust the extraction power for being supplied to the drain needle.
10. pumping equipment according to claim 9, which is characterized in that the draw-off pump is diaphragm pump, and the drain fills
Setting further comprises the first solenoid valve in the drain line being arranged between the isolation ward and the diaphragm pump, described first
Solenoid valve is two-position three way magnetic valve, and the isolation ward is provided with the first opening, the second opening and third opening, wherein institute
The sidewall upper that the isolation ward is arranged in the first opening is stated, the side wall lower ends of the isolation ward are arranged in second opening,
And the top of the isolation ward is arranged in the third opening, the normally open end of first solenoid valve is connected by drain line
To the first opening of the isolation ward, the normal-closed end of first solenoid valve is connected to the isolation ward by drain line
Second opening, the working end of first solenoid valve is connected to the draw-off pump by drain line；And the isolation ward
Third opening is connected to the drain needle by drain line.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201821202148.3U CN209034981U (en) | 2018-07-26 | 2018-07-26 | Cleaning device and pumping equipment |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201821202148.3U CN209034981U (en) | 2018-07-26 | 2018-07-26 | Cleaning device and pumping equipment |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN209034981U true CN209034981U (en) | 2019-06-28 |
Family
ID=67030020
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201821202148.3U Active CN209034981U (en) | 2018-07-26 | 2018-07-26 | Cleaning device and pumping equipment |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN209034981U (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110756499A (en) * | 2018-07-26 | 2020-02-07 | 深圳市帝迈生物技术有限公司 | Cleaning device, liquid discharge device and corresponding cleaning method |
-
2018
- 2018-07-26 CN CN201821202148.3U patent/CN209034981U/en active Active
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110756499A (en) * | 2018-07-26 | 2020-02-07 | 深圳市帝迈生物技术有限公司 | Cleaning device, liquid discharge device and corresponding cleaning method |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN209034981U (en) | Cleaning device and pumping equipment | |
| JP6427586B2 (en) | Water flow controller, water flow control method, water flow control device, program and recording medium | |
| CN109770437A (en) | A kind of electronic cigarette liquid Magnetic driving pumping installations and its electronics tobacco product | |
| CN103925186A (en) | Electromagnetic reciprocating pump | |
| CN209387380U (en) | A kind of magnetic separating device and device for analyzing samples | |
| CN204533741U (en) | A kind of self-holding electromagnetic valve | |
| CN209146387U (en) | A kind of low-power consumption self-holding electromagnetic valve | |
| CN108918901B (en) | Multichannel flow path structure of biochemical multi-component concentration online analyzer | |
| CN110756499A (en) | Cleaning device, liquid discharge device and corresponding cleaning method | |
| CN209687670U (en) | Continuous flow injection pump system | |
| CN102656365A (en) | Pump for a high pressure cleaning device | |
| CN110953383A (en) | Check valve of vacuum pump | |
| CN109826772A (en) | Continuous flow injection pump system and control method thereof | |
| CN106436186A (en) | Method and apparatus injecting washing assistant via water inlet valve of washing machine | |
| CN106149306A (en) | Washing machine inflow electromagnetic valve is utilized to inject the method and device of liquid washing assisant | |
| CN110873660A (en) | Magnetic separation device, magnetic separation method and sample analysis device | |
| CN210920273U (en) | Normally closed high-speed digital switch valve | |
| CN200995170Y (en) | Efficient magnetic concentrator with iron-removing function | |
| CN204201234U (en) | One is novel has single switch dual channel function electromagnetic water valve | |
| CN109356865A (en) | A kind of integrated form flow double-control apparatus for water pump | |
| CN209588267U (en) | Water tank and humidifier with dual water valve | |
| CN211900941U (en) | Stepless air volume adjusting air valve operation structure and hydraulic damping device thereof | |
| CN208415442U (en) | Toilet seat, flushing mechanism and hydraulic stroke switch | |
| CN209586646U (en) | A kind of split type flow double-control apparatus for water pump | |
| CN209800828U (en) | liquid-through electromagnetic valve |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| PP01 | Preservation of patent right |
Effective date of registration: 20200528 Granted publication date: 20190628 |
|
| PP01 | Preservation of patent right | ||
| PD01 | Discharge of preservation of patent |
Date of cancellation: 20220919 Granted publication date: 20190628 |
|
| PD01 | Discharge of preservation of patent |