CN207845533U - A kind of chondroitin sulfate production line - Google Patents
A kind of chondroitin sulfate production line Download PDFInfo
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- CN207845533U CN207845533U CN201721758711.0U CN201721758711U CN207845533U CN 207845533 U CN207845533 U CN 207845533U CN 201721758711 U CN201721758711 U CN 201721758711U CN 207845533 U CN207845533 U CN 207845533U
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- filter
- paddle
- chondroitin sulfate
- autoclave body
- agitating shaft
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Abstract
A kind of chondroitin sulfate production line, including the reaction kettle to connect successively, filter plant, concentrator, oxidation tank, Alcohol-settling tank, centrifuge and drying machine, the reaction kettle includes autoclave body, rabbling mechanism is equipped in autoclave body, rabbling mechanism includes blender and supporting rack, blender includes agitating shaft, agitating shaft extends downwardly into autoclave body, agitating shaft is equipped with upper agitating paddle and lower stirring paddle, upper agitating paddle is vertically arranged with agitating shaft with lower stirring paddle, and the blade of upper agitating paddle and the blade crossings of lower stirring paddle are arranged, supporting rack is fixed in autoclave body, the rotary drive mechanism of driving agitating shaft rotation is equipped on supporting rack, it is equipped with to help in autoclave body between the upper agitating paddle and lower stirring paddle and stirs plate, the one end for stirring plate and autoclave body is helped to be detachably connected, the other end for stirring plate is helped to be arranged towards agitating shaft.The utility model is easy to operate, shortens the production cycle of chondroitin sulfate, improves product purity.
Description
Technical field
The utility model belongs to chondroitin production equipment technology, and in particular to a kind of chondroitin sulfate production line.
Background technology
Currently, chondroitin sulfate（CS）Mainly it is prepared by the heavy technique of alkali carries-enzymolysis -ol.The raw material for producing CS is more
For animal cartilage, gristle, sea urchin, cuttlefish etc., CS exists in animal tissue in the form of proteoglycan, polysaccharide chain and core
Heart protein needs alkali carries, enzymolysis step to destroy the covalent bond between polysaccharide chain and protein, keeps albumen more by being covalently keyed
The sugar of sugar-peptide bond fracture, to release CS.Therefore the reaction kettle that alkali carries, enzymolysis use is very crucial.It is existing anti-
It answers kettle mixing effect poor, the alkali of raw material and addition, enzyme can not be made to be sufficiently mixed, alkaline hydrolysis and enzyme digestion reaction are insufficient.Moreover, common
Chondroitin sulfate production line it is long there are the production cycle, ineffective phenomenon, simultaneously as the filter plant used cannot
It is enough that contaminant filter in feed liquid is complete, cause chondroitin sulfate product purity low.
Invention content
The technical problems to be solved in the utility model is in view of the deficiencies of the prior art, it is proposed that a kind of mixing effect is good,
Chondroitin sulfate production line with short production cycle.
The technical problems to be solved in the utility model is achieved through the following technical solutions, a kind of chondroitin sulfate life
Producing line, its main feature is that, including the reaction kettle, filter plant, concentrator, oxidation tank, Alcohol-settling tank, the centrifuge and dry that connect successively
Dry machine, the reaction kettle include autoclave body, and rabbling mechanism is equipped in autoclave body, and rabbling mechanism includes blender and supporting rack, described
Blender includes agitating shaft, and agitating shaft extends downwardly into autoclave body, and agitating shaft is equipped with upper agitating paddle and lower stirring paddle, upper agitating paddle
It is vertically arranged with agitating shaft with lower stirring paddle, and the paddle of upper agitating paddle and the paddle of lower stirring paddle are staggered, the branch
Support is fixed in autoclave body, on supporting rack be equipped with driving agitating shaft rotation rotary drive mechanism, the upper agitating paddle with
It is equipped with to help in autoclave body between lower stirring paddle and stirs plate, help the one end for stirring plate and autoclave body to be detachably connected, help the other end court for stirring plate
It is arranged to agitating shaft.
Further, the rotary drive mechanism is driving motor.
Further, the filter plant includes the filter pipeline to connect with the discharge port of reaction kettle, in filter pipeline
On successively be equipped with the first security filter, feed pump, storage tank, inlet valve, the second security filter and postposition film filter,
Filter pipeline between storage tank and inlet valve is equipped with waste-solution line, and waste-solution line is equipped with waist valve, the filtering of the second security
Filter pipeline between device and postposition film filter is equipped with charging pump, and postposition film filter includes exhaust end and waste discharge
The exhaust end at end, postposition film filter is equipped with marker pipe, and marker pipe is equipped with blow-off valve, the row of postposition film filter
Useless end is connected by return line with storage tank.
Further, the postposition film filter includes at least two wound membrane filtration components being connected in parallel, often
A wound membrane filtration component includes two wound membrane filtration elements being connected in parallel.
Further, the wound membrane filtration element is roll-to-roll ultrafiltration membrane component.
Further, the molecular cut off of the ultrafiltration membrane is 7kD-13 kD.
Further, the marker pipe between the blow-off valve and the exhaust end of postposition film filter is equipped with and storage
The circulation line of filter pipeline connection between batch can and preposition prefilter, circulation line are equipped with circulating valve.
Further, the concentrator is double effect evaporator or ultra low temperature vacuum thickener.
Further, the drying machine is vacuum freeze drier.
The utility model puts into reaction kettle compared with prior art, by well-done raw material, and the feed liquid through alkaline hydrolysis, enzymolysis is logical
Cross filter device filtering, the concentrated equipment concentration of filtered liquid, oxidation tank oxidative decoloration, Alcohol-settling tank settle, centrifuge,
It takes the precipitation after centrifugation to be sent into drying machine to dry to get chondroitin sulfate.Wherein, helping of being arranged in autoclave body, which stirs plate, can make reaction
Material in kettle mixes more uniform, improves reaction efficiency, shortens the reaction time；Meanwhile hydrolyzate is followed by filter plant
Ring is filtered for multiple times, and very big the impurity reduced in solution adsorbs without resin column, simplifies technique, with short production cycle.This reality
It is convenient with novel operating, the production cycle of chondroitin sulfate is shortened, product purity is improved.
Description of the drawings
Fig. 1 is the overall structure diagram of the utility model；
Fig. 2 is the structural schematic diagram of the utility model filter plant；
Fig. 3 is the structural schematic diagram of the utility model postposition film filter.
Specific implementation mode
With reference to specific embodiment and its attached drawing, the utility model is described in further detail, but this practicality is new
The embodiment of type is not limited only to this.
Embodiment 1, a kind of chondroitin sulfate production line, referring to Fig.1-3, including the reaction kettle 1, the filter plant that connect successively
2, concentrator 3, oxidation tank 4, Alcohol-settling tank 5, centrifuge 6 and drying machine 7, the reaction kettle 1 includes autoclave body 12, in autoclave body 12
Equipped with rabbling mechanism, rabbling mechanism includes blender and supporting rack 16, and the blender includes agitating shaft 15, and agitating shaft 15 is downward
Stretch into autoclave body 12, agitating shaft 15 is equipped with upper agitating paddle 14 and lower stirring paddle 11, upper agitating paddle 14 and lower stirring paddle 11 with
Agitating shaft 15 is vertically arranged, and the paddle of upper agitating paddle 14 and the paddle of lower stirring paddle 11 are staggered, and support frame as described above 16 is solid
It is scheduled in autoclave body 12, the rotary drive mechanism 17 that driving agitating shaft 15 rotates, the upper agitating paddle 14 is equipped on supporting rack 16
It is equipped with to help in autoclave body 12 between lower stirring paddle 11 and stirs plate 13, help the one end for stirring plate 13 and autoclave body 12 to be detachably connected, help and stir
The other end of plate 13 is arranged towards agitating shaft 15, and described helping stir plate 13 and be detachably arranged on autoclave body 12, be conducive to its into
Row maintenance and cleaning.
Embodiment 2, in chondroitin sulfate production line described in embodiment 1, the rotary drive mechanism 17 is driving electricity
Machine.
Embodiment 3, in chondroitin sulfate production line described in embodiment 1, the filter plant 2 includes and reaction kettle 1
The filter pipeline 21 that connects of discharge port, be equipped with the first security filter 22, feed pump 23, storing successively on filter pipeline 21
Tank 24, inlet valve 214, the second security filter 212 and postposition film filter 29, between storage tank 24 and inlet valve 214
Filter pipeline 21 is equipped with waste-solution line 217, and waste-solution line 217 is equipped with waist valve 216, and the second security filter 212 is with after
It sets the filter pipeline 21 between film filter 29 and is equipped with charging pump 210, postposition film filter 29 includes 292 He of exhaust end
The exhaust end 292 at waste discharge end 291, postposition film filter 29 is equipped with marker pipe 27, and marker pipe 27 is equipped with blow-off valve 28,
The waste discharge end 291 of postposition film filter 29 is connected by return line 26 with storage tank 24, the first security filter
22 and second security filter 212 be conducive to treat larger impurity in filtering feed liquid and carry out pre-filtering, to remove 1 degree of turbidity or more
Fine particles, avoid postposition film filter 29 from being blocked in use, then by postposition film filter 29 to it
Refined filtration is carried out, the purity of product is improved.
Embodiment 4, in chondroitin sulfate production line described in embodiment 3, the postposition film filter 29 includes extremely
Few two wound membrane filtration components 293 being connected in parallel, each wound membrane filtration component 293 include two volumes being connected in parallel
Formula film filtering element 2931.
Embodiment 5, in the chondroitin sulfate production line described in embodiment 4, the wound membrane filtration element 2931 is volume
Formula ultrafiltration membrane elements.
Embodiment 6, in the chondroitin sulfate production line described in embodiment 5, the molecular cut off of the ultrafiltration membrane is
7kD-13 kD。
Embodiment 7, in chondroitin sulfate production line described in embodiment 3, the blow-off valve 28 and postposition membrane filtration dress
Set the filtering that the marker pipe 27 between 29 exhaust end 292 is equipped between storage tank 24 and the second security filter 212
The circulation line 25 that pipeline 21 is connected to, circulation line 25 are equipped with circulating valve 213, observation are equipped on the circulation line 25
Mouth 215；Increased circulation line 25 be conducive to it is for re-filtering to the filtered solution containing chondroitin sulfate, directly
It is more clarified to obtained solution, the clarification degree of solution can be observed by the observation panel 215 on circulation line 25.
Embodiment 8, in chondroitin sulfate production line described in embodiment 1, the concentrator 3 be double effect evaporator or
Ultra low temperature vacuum thickener.
Embodiment 9, in chondroitin sulfate production line described in embodiment 1, the drying machine 7 is vacuum freeze drying
Machine can avoid chondroitin sulfate destructurized in the drying process.
When the utility model is used, the producer can also be according to needs of production, such as a large amount of or a small amount of production, to rolling
The quantity of membrane component 2931 is increased and decreased.
Claims (9)
1. a kind of chondroitin sulfate production line, it is characterised in that：Including connect successively reaction kettle, filter plant, concentrator,
Oxidation tank, Alcohol-settling tank, centrifuge and drying machine, the reaction kettle include autoclave body, and rabbling mechanism, rabbling mechanism are equipped in autoclave body
Including blender and supporting rack, the blender includes agitating shaft, and agitating shaft extends downwardly into autoclave body, and agitating shaft is equipped with and above stirs
Paddle and lower stirring paddle are mixed, upper agitating paddle is vertically arranged with agitating shaft with lower stirring paddle, and the paddle blade of upper agitating paddle is stirred under
The paddle blade crossings setting of paddle is mixed, support frame as described above is fixed in autoclave body, and the rotation of driving agitating shaft rotation is equipped on supporting rack
Turn driving mechanism, is equipped with to help in the autoclave body between the upper agitating paddle and lower stirring paddle and stirs plate, help the one end for stirring plate and autoclave body
It is detachably connected, the other end for stirring plate is helped to be arranged towards agitating shaft.
2. chondroitin sulfate production line according to claim 1, it is characterised in that：The rotary drive mechanism is driving
Motor.
3. chondroitin sulfate production line according to claim 1, it is characterised in that：The filter plant includes and reacts
The filter pipeline that the discharge port of kettle connects is equipped with the first security filter, feed pump, storage tank, confession successively on filter pipeline
Expect valve, the second security filter and postposition film filter, the filter pipeline between storage tank and inlet valve is equipped with sewer pipe
Road, waste-solution line are equipped with waist valve, and the filter pipeline between the second security filter and postposition film filter, which is equipped with, to be supplied
Material pump, postposition film filter include exhaust end and waste discharge end, and the exhaust end of postposition film filter is equipped with marker pipe, discharge
Pipeline is equipped with blow-off valve, and the waste discharge end of postposition film filter is connected by return line with storage tank.
4. chondroitin sulfate production line according to claim 3, it is characterised in that：The postposition film filter includes
At least two wound membrane filtration components being connected in parallel, each wound membrane filtration component include two rolled films being connected in parallel
Filter element.
5. chondroitin sulfate production line according to claim 4, it is characterised in that：The wound membrane filtration element is volume
Formula ultrafiltration membrane elements.
6. chondroitin sulfate production line according to claim 5, it is characterised in that：The molecular cut off of the ultrafiltration membrane
For 7kD-13 kD.
7. chondroitin sulfate production line according to claim 3, it is characterised in that：The blow-off valve and postposition membrane filtration
Marker pipe between the exhaust end of device is equipped with what the filter pipeline between storage tank and the second security filter was connected to
Circulation line, circulation line are equipped with circulating valve.
8. chondroitin sulfate production line according to claim 1, it is characterised in that：The concentrator is double-effect evaporation
Device or ultra low temperature vacuum thickener.
9. chondroitin sulfate production line according to claim 1, it is characterised in that：The drying machine is dry for vacuum refrigeration
Dry machine.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201721758711.0U CN207845533U (en) | 2017-12-16 | 2017-12-16 | A kind of chondroitin sulfate production line |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201721758711.0U CN207845533U (en) | 2017-12-16 | 2017-12-16 | A kind of chondroitin sulfate production line |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN207845533U true CN207845533U (en) | 2018-09-11 |
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ID=63420919
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201721758711.0U Active CN207845533U (en) | 2017-12-16 | 2017-12-16 | A kind of chondroitin sulfate production line |
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| CN (1) | CN207845533U (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111704681A (en) * | 2020-07-03 | 2020-09-25 | 山东冰文生物技术有限公司 | Intelligent chondroitin sulfate production line |
-
2017
- 2017-12-16 CN CN201721758711.0U patent/CN207845533U/en active Active
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111704681A (en) * | 2020-07-03 | 2020-09-25 | 山东冰文生物技术有限公司 | Intelligent chondroitin sulfate production line |
| CN111704681B (en) * | 2020-07-03 | 2022-02-08 | 山东海钰生物技术股份有限公司 | Intelligent chondroitin sulfate production line |
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