CN207163992U - High-precision liquid chromatograph - Google Patents
High-precision liquid chromatograph Download PDFInfo
- Publication number
- CN207163992U CN207163992U CN201721140546.2U CN201721140546U CN207163992U CN 207163992 U CN207163992 U CN 207163992U CN 201721140546 U CN201721140546 U CN 201721140546U CN 207163992 U CN207163992 U CN 207163992U
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- Prior art keywords
- chromatograph
- main body
- chromatograph main
- internally provided
- main part
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- 239000007788 liquid Substances 0.000 title claims abstract description 38
- 230000007246 mechanism Effects 0.000 claims abstract description 20
- 238000003860 storage Methods 0.000 claims abstract description 14
- 238000005406 washing Methods 0.000 claims description 15
- 238000012360 testing method Methods 0.000 claims description 10
- 230000005540 biological transmission Effects 0.000 claims description 8
- 238000009849 vacuum degassing Methods 0.000 claims description 8
- 230000008520 organization Effects 0.000 claims description 7
- 239000000203 mixture Substances 0.000 claims description 6
- 238000013461 design Methods 0.000 abstract description 4
- 239000002904 solvent Substances 0.000 abstract description 3
- 238000001514 detection method Methods 0.000 abstract description 2
- 239000011550 stock solution Substances 0.000 abstract 3
- 230000007306 turnover Effects 0.000 abstract 1
- 238000004140 cleaning Methods 0.000 description 8
- 238000004458 analytical method Methods 0.000 description 6
- 238000010586 diagram Methods 0.000 description 3
- 230000000694 effects Effects 0.000 description 3
- 230000009286 beneficial effect Effects 0.000 description 2
- 239000003814 drug Substances 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 238000000506 liquid--solid chromatography Methods 0.000 description 2
- 239000007787 solid Substances 0.000 description 2
- 238000006467 substitution reaction Methods 0.000 description 2
- 239000012498 ultrapure water Substances 0.000 description 2
- 230000005526 G1 to G0 transition Effects 0.000 description 1
- OAICVXFJPJFONN-UHFFFAOYSA-N Phosphorus Chemical compound [P] OAICVXFJPJFONN-UHFFFAOYSA-N 0.000 description 1
- 230000033228 biological regulation Effects 0.000 description 1
- 238000004587 chromatography analysis Methods 0.000 description 1
- 238000013016 damping Methods 0.000 description 1
- 238000007872 degassing Methods 0.000 description 1
- 238000009826 distribution Methods 0.000 description 1
- 238000010828 elution Methods 0.000 description 1
- 238000003891 environmental analysis Methods 0.000 description 1
- 238000011010 flushing procedure Methods 0.000 description 1
- 238000004128 high performance liquid chromatography Methods 0.000 description 1
- 238000001802 infusion Methods 0.000 description 1
- 238000004811 liquid chromatography Methods 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 239000003960 organic solvent Substances 0.000 description 1
- 229910052698 phosphorus Inorganic materials 0.000 description 1
- 239000011574 phosphorus Substances 0.000 description 1
- 230000000704 physical effect Effects 0.000 description 1
- 238000010926 purge Methods 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 210000003296 saliva Anatomy 0.000 description 1
- 238000005070 sampling Methods 0.000 description 1
- 230000007704 transition Effects 0.000 description 1
Landscapes
- Sampling And Sample Adjustment (AREA)
Abstract
The utility model discloses a high accuracy liquid chromatograph, including the chromatograph main part, the top of chromatograph main part is provided with vacuum degasser, vacuum degasser's top is provided with stock solution mechanism, the inside of stock solution mechanism is provided with the stock solution bottle, the inside of chromatograph main part is provided with control mechanism, control mechanism's surface is provided with the display screen, adjust knob and switch, the bottom of display screen is provided with a plurality of selection button, the inside of chromatograph main part is provided with the sample cabinet, the inside of chromatograph main part is provided with puts the thing structure, the inside of chromatograph main part is provided with chromatogram detection mechanism. Through setting up supersonic generator and impeller, be convenient for wash and form smooth even oxide film at the internal surface of chromatogram pump solvent filter head, business turn over mouth valve and pipeline, the storage space has been increased to the inside thing space of putting of liquid chromatograph moreover, and the design is simple reasonable, has improved the precision of chromatograph.
Description
Technical field
Biochemical field is the utility model is related to, more particularly to a kind of high-precision liquid chromatograph.
Background technology
Liquid chromatograph is a kind of difference using mixture distribution ratio between liquid-solid or immiscible two kinds of liquid,
Mixture is first separated, the instrument then analyzed and identified.Liquid chromatograph is liquid or solid according to stationary phase, is divided again
For LLC (LLC) and liquid-solid chromatography (LSC).Modern liquid chromatography instrument is by high pressure pump, sampling system, temperature control
The part such as system, chromatographic column, detector, signal recording system forms.Liquid chromatograph is widely applied to biochemistry, food
The various fields such as analysis, medical research, environmental analysis, inorganic analysis, liquid chromatograph have height compared with classical chromatograph
The advantages that imitating, be quick, sensitive.
But present liquid chromatograph still has the problem of many.Existing liquid chromatograph typically all simply by
One infusion pump, a detector composition, and also complete cleaning difficulty is bigger after use, and not depth cleaning can influence liquid
The precision of chromatography, existing technology are difficult to solve problem above.
Utility model content
The technical problems to be solved in the utility model is to overcome existing liquid chromatograph typically all simply by a transfusion
Pump, a detector composition, and also cleaning difficulty is bigger after use, and not depth cleaning can influence the essence of liquid chromatograph
A kind of the problem of spending, there is provided high-precision liquid chromatograph.
In order to solve the above-mentioned technical problem, the utility model provides following technical scheme：
A kind of high-precision liquid chromatograph of the utility model, including chromatograph main body, the top of the chromatograph main body are set
Vacuum degassing machine is equipped with, the top of the vacuum degassing machine is provided with liquid storage mechanism, and the liquid storage mechanism is internally provided with storage
Liquid bottle, the chromatograph main body are internally provided with controlling organization, and the surface of the controlling organization is provided with display screen, regulation rotation
Button and switch, the bottom of the display screen are provided with some select buttons, and the chromatograph main body is internally provided with sample
Cabinet, the chromatograph main body are internally provided with containing structure, and the chromatograph main body is internally provided with chromatogram testing agency,
The chromatogram testing agency is internally provided with temperature management system, and the chromatogram testing agency is internally provided with some chromatograms
Post, the surface of some chromatographic columns are provided with switching valve, and the top of some chromatographic columns is provided with connector, described
Chromatograph main body is internally provided with transmission mechanism, and the top of the chromatograph main body is provided with analytical instrument, the chromatogram
The side of instrument main body is provided with high-efficiency washing device, and the bottom of the high-efficiency washing device is provided with some fixed seats, the height
Effect cleaning device is internally provided with supersonic generator, and the top of the supersonic generator is provided with agitator arm, described
The top of agitator arm is provided with fixed support.
As a kind of optimal technical scheme of the present utility model, the transmission mechanism by threeway, pump head, plunger, driven pulley,
Cam and camshaft composition.
As a kind of optimal technical scheme of the present utility model, the chromatograph main body is fixed with the analytical instrument to be connected
Connect.
As a kind of optimal technical scheme of the present utility model, the high-efficiency washing device passes through with the chromatograph main body
Screw connection.
As a kind of optimal technical scheme of the present utility model, some fixed seats are made by rubber.
The beneficial effect that the utility model is reached is：The utility model is by setting supersonic generator and paddle
Wheel, it is easy to form smooth even in the cleaning of chromatogram pump solvent filter head, terminal valve and pipeline and in its inner surface
Oxide-film, and the material-putting space inside liquid chromatograph, memory space is added, design advantages of simple, improve chromatograph
Precision.
Brief description of the drawings
Accompanying drawing is used for providing further understanding to of the present utility model, and a part for constitution instruction, with this practicality
New embodiment is used to explain the utility model together, does not form to limitation of the present utility model.In the accompanying drawings：
Fig. 1 is overall structure diagram of the present utility model；
Fig. 2 is one of partial structural diagram of the present utility model；
Fig. 3 is the two of partial structural diagram of the present utility model；
In figure：1st, chromatograph main body；2nd, vacuum degassing machine；3rd, liquid storage mechanism；4th, liquid storage bottle；5th, controlling organization；6th, sample
Cabinet；7th, high-efficiency washing device；8th, containing structure；9th, temperature management system；10th, chromatographic column；11st, switching valve；12nd, connector；13、
Chromatogram testing agency；14th, analytical instrument；15th, transmission mechanism；16th, display screen；17th, select button；18th, adjusting knob；19、
Switch；20th, supersonic generator；21st, fixed support；22nd, fixed seat；23rd, agitator arm.
Embodiment
Preferred embodiment of the present utility model is illustrated below in conjunction with accompanying drawing, it will be appreciated that described herein excellent
Select embodiment to be merely to illustrate and explain the utility model, be not used to limit the utility model.
Embodiment 1
As Figure 1-3, the utility model provides a kind of high-precision liquid chromatograph, including chromatograph main body 1, chromatograph
The top of main body 1 is provided with vacuum degassing machine 2, and the top of vacuum degassing machine 2 is provided with liquid storage mechanism 3, the inside of liquid storage mechanism 3
Be provided with liquid storage bottle 4, chromatograph main body 1 is internally provided with controlling organization 5, the surface of controlling organization 5 be provided with display screen 16,
Adjusting knob 18 and switch 19, the bottom of display screen 16 are provided with some select buttons 17, and the inside of chromatograph main body 1 is set
There is sample cabinet 6, chromatograph main body 1 is internally provided with containing structure 8, and chromatograph main body 1 is internally provided with chromatogram detection machine
Structure 13, chromatogram testing agency 13 is internally provided with temperature management system 9, if chromatogram testing agency 13 is internally provided with dry color
Post 10 is composed, the surface of some chromatographic columns 10 is provided with switching valve 11, and the top of some chromatographic columns 10 is provided with connector 12,
Chromatograph main body 1 is internally provided with transmission mechanism 15, and the top of chromatograph main body 1 is provided with analytical instrument 14, chromatograph
The side of main body 1 is provided with high-efficiency washing device 7, and the bottom of high-efficiency washing device 7 is provided with some fixed seats 22, high-efficiency washing
Device 7 is internally provided with supersonic generator 20, and the top of supersonic generator 20 is provided with agitator arm 23, agitator arm
23 top is provided with fixed support 21.
Transmission mechanism 15 is made up of threeway, pump head, plunger, driven pulley, cam and camshaft, adds the biography of the device
Dynamic effect, and design advantages of simple.
Chromatograph main body 1 is fixedly connected with analytical instrument 14, and a stable job is provided for analytical instrument 14
Environment.
High-efficiency washing device 7, by screw connection, high-efficiency washing device 7 and chromatograph main body 1 is consolidated with chromatograph main body 1
It is scheduled on the stability that together, ensure that high-efficiency washing device 7 works.
Some fixed seats 22 are made by rubber, and physical property is good, and have good damping effect.
Specifically, when this apparatus is used, medicament being imported by liquid storage bottle 4, entered back into vacuum degassing machine 2, carry out
Degassing process, subsequent medicament by transmission mechanism 15, operate in the pipeline of equipment again, are carried out in incoming chromatographic column 10 first
Analysis, chromatogram testing agency 13 is internally provided with temperature management system 9, and the temperature around chromatographic column 10 can be controlled
System, avoids high temperature from having an impact the analysis result of chromatographic column 10, the switching valve 11 in chromatographic column 10 can quickly realize chromatogram
Selection between post 10, so as to which the exploitation of unserviced HPLC methods can be realized, enter back into analytical instrument 14 carry out it is secondary
Analysis, the result of analysis can be reflected on the display screen 16 of controlling organization 5, meanwhile, the sample analyzed can be placed on sample slot
Observed, the containing structure 8 inside chromatograph main body 1 may be used as storage article, and after use, chromatographic column 10 is taken
Under, led to two and connect injector and detector, all suction strainer heads are put into inside high-efficiency washing device 7, while open ultrasonic wave
Generator 20, with 1.0ml/min flow velocity transition, treating that organic solvent elution is clean in pipeline in high purity water；Use 30% phosphorus instead again
Sour purging system, then high purity water flushing is changed, until it is about 6~7 to go out saliva pH value, cleaning is completed.
The beneficial effect that the utility model is reached is：The utility model is by setting supersonic generator and paddle
Wheel, it is easy to form smooth even in the cleaning of chromatogram pump solvent filter head, terminal valve and pipeline and in its inner surface
Oxide-film, and the material-putting space inside liquid chromatograph, memory space is added, design advantages of simple, improve chromatograph
Precision.
Finally it should be noted that：Preferred embodiment of the present utility model is the foregoing is only, is not limited to this
Utility model, although the utility model is described in detail with reference to the foregoing embodiments, for those skilled in the art
For, it can still modify to the technical scheme described in foregoing embodiments, or to which part technical characteristic
Carry out equivalent substitution.All any modification, equivalent substitution and improvements within the spirit and principles of the utility model, made etc.,
It should be included within the scope of protection of the utility model.
Claims (5)
1. a kind of high-precision liquid chromatograph, including chromatograph main body (1), it is characterised in that the top of the chromatograph main body (1)
End is provided with vacuum degassing machine (2), and the top of the vacuum degassing machine (2) is provided with liquid storage mechanism (3), the liquid storage mechanism
(3) be internally provided with liquid storage bottle (4), the chromatograph main body (1) is internally provided with controlling organization (5), the control machine
The surface of structure (5) is provided with display screen (16), adjusting knob (18) and switch (19), and the bottom of the display screen (16) is set
There are some select buttons (17), the chromatograph main body (1) is internally provided with sample cabinet (6), the chromatograph main body (1)
Containing structure (8) is internally provided with, the chromatograph main body (1) is internally provided with chromatogram testing agency (13), the chromatogram
Testing agency (13) is internally provided with temperature management system (9), and being internally provided with for the chromatogram testing agency (13) is some
Chromatographic column (10), the surface of some chromatographic columns (10) are provided with switching valve (11), the top of some chromatographic columns (10)
End is provided with connector (12), and the chromatograph main body (1) is internally provided with transmission mechanism (15), the chromatograph main body
(1) top is provided with analytical instrument (14), and the side of the chromatograph main body (1) is provided with high-efficiency washing device (7), institute
The bottom for stating high-efficiency washing device (7) is provided with some fixed seats (22), and being internally provided with for the high-efficiency washing device (7) is super
Sonic generator (20), the top of the supersonic generator (20) are provided with agitator arm (23), the agitator arm (23)
Top be provided with fixed support (21).
2. a kind of high-precision liquid chromatograph according to claim 1, it is characterised in that the transmission mechanism (15) is by three
Logical, pump head, plunger, driven pulley, cam and camshaft composition.
A kind of 3. high-precision liquid chromatograph according to claim 1, it is characterised in that the chromatograph main body (1) with
The analytical instrument (14) is fixedly connected.
A kind of 4. high-precision liquid chromatograph according to claim 1, it is characterised in that the high-efficiency washing device (7)
Pass through screw connection with the chromatograph main body (1).
5. a kind of high-precision liquid chromatograph according to claim 1, it is characterised in that some fixed seats (22) are equal
It is made up of rubber.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201721140546.2U CN207163992U (en) | 2017-09-07 | 2017-09-07 | High-precision liquid chromatograph |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201721140546.2U CN207163992U (en) | 2017-09-07 | 2017-09-07 | High-precision liquid chromatograph |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN207163992U true CN207163992U (en) | 2018-03-30 |
Family
ID=61720644
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201721140546.2U Expired - Fee Related CN207163992U (en) | 2017-09-07 | 2017-09-07 | High-precision liquid chromatograph |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN207163992U (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108398518A (en) * | 2018-05-03 | 2018-08-14 | 苏杰 | A kind of liquid chromatograph |
| CN108802224A (en) * | 2018-06-14 | 2018-11-13 | 潍坊学院 | A kind of high-precision traditional Chinese medicine ingredients liquid chromatography system |
-
2017
- 2017-09-07 CN CN201721140546.2U patent/CN207163992U/en not_active Expired - Fee Related
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108398518A (en) * | 2018-05-03 | 2018-08-14 | 苏杰 | A kind of liquid chromatograph |
| CN108802224A (en) * | 2018-06-14 | 2018-11-13 | 潍坊学院 | A kind of high-precision traditional Chinese medicine ingredients liquid chromatography system |
| CN108802224B (en) * | 2018-06-14 | 2021-07-02 | 肖飞 | High accuracy traditional chinese medicine composition liquid chromatography analytical equipment |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20180330 Termination date: 20200907 |
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| CF01 | Termination of patent right due to non-payment of annual fee |