CN206330984U - A kind of preoperative four measurement systems of full-automatic fluorescent immune method - Google Patents
A kind of preoperative four measurement systems of full-automatic fluorescent immune method Download PDFInfo
- Publication number
- CN206330984U CN206330984U CN201621135595.2U CN201621135595U CN206330984U CN 206330984 U CN206330984 U CN 206330984U CN 201621135595 U CN201621135595 U CN 201621135595U CN 206330984 U CN206330984 U CN 206330984U
- Authority
- CN
- China
- Prior art keywords
- antibody
- automatic
- sample
- preoperative
- detection
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Landscapes
- Sampling And Sample Adjustment (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
Abstract
The utility model discloses a kind of full-automatic preoperative four measurement systems of fluorescent immune method, including for detecting the automatic tester of sample and kit for containing test paper piece, automatic tester passes through automatic sampling, dilution mixing, and detected by the test paper piece in kit, the use of fluorescent immune method than the advantage that traditional enzyme process luminescence method is determined is economic low consumption, it is quick timely, high degree of automation, medical treatment pollution is small, qualitative, quantitative all may be used, meet the quick detection requirement of clinical patient, detected while realizing preoperative four, improve the precision of test, improve the efficiency of detection.
Description
Technical field
The utility model is related to medical inspection field, specifically a kind of preoperative four measure of full-automatic fluorescent immune method
System.
Background technology
Fluorescence immunoassay technology is to carry out a kind of of antigen-antibody positioning and quantitative measure according to labelled antibody to examine skill
Art, claims fluorescence anti-body method with the method for fluorescence antibody spike or inspection corresponding antigens；With known fluorescent antigen label spike
Or check the method fluorescent antigen method of corresponding antibodies；Both approaches general name immunofluorescence technique.Because fluorchrome not only can
Combined, for detecting or positioning various antigens, can also be combined with other globulin, for detecting or positioning with antibody globulin
Various antigens, can also with other protein bindings, for checking or positioning antibody.
The detection of preoperative four in the past is constantly in qualitative or sxemiquantitative state by hand, in actually detected, traditional enzyme
The finding speed of method luminescence method is slow, and operating process is cumbersome, and detection time is long, inefficiency, and high cost adds testing staff's
Burden, it is impossible to meet the quick detection requirement of clinical patient.
Chinese patent CN104535782A discloses a kind of full-automatic fluorescence immunoassay quantitative analysis device and implementation method, should
Immune quantitative analytical equipment includes support baseboard, reagent strip storage and automatic load-on module, reaction disk module, detection module, sample
This module, sample-adding module, wash module and control system, reagent strip storage and automatic load-on module, reaction disk module, detection mould
Block, sample module, sample-adding module, wash module are sequentially arranged on support baseboard, and the reagent strip stores and loaded automatically mould
Block provides reagent strip for reaction disk module, and the sample in sample module is added in reaction disk module and carried out instead by sample-adding module
Should, complete to enter detection module completion detection after reaction, the utility model solves in-vitro diagnosis product and is difficult to automation
Problem, reduce human error, improve the precision of test, improve detection efficiency, but fail to realize preoperative four
Detect simultaneously, status requirement high precision, the dilution liquid bath arrangement mixed in box is close, and status requirement is very strict, machinery such as occurs
Failure, easily error causes diagnosis to malfunction.
Chinese patent CN102087215A discloses a kind of fluorescent quantitative detector, and it includes excitation source module, photoelectricity
Modular converter, control analysis module and software systems, the excitation source module include first laser modular assembly and second and swashed
Optical mode block assembly；First laser modular assembly is used into the detection zone of reagent strip launch excitation beam A；Second laser module group
Part is used to launch excitation beam B to the code area on reagent strip；The photoelectric conversion module is used for the fluorescence signal C for receiving reflection
With laser signal D and carry out photoelectric signal transformation；The control analysis module includes main circuit, motor, display screen, control analysis
Module is used to handle the electric signal for receiving photoelectric conversion module output, and the utility model fluorescent quantitative detector uses particular design
Optical system and compensation circuit, make immunofluorescence quantify detection it is sensitiveer and accurate, but can only quantitatively use, can not determine
Property is used.
Utility model content
Problem to be solved in the utility model is to realize preoperative four surveys of fluorescent immune method using fluorescence immunoassay technology
Fixed qualitative and quantitative detection automatically, meets clinical quick detection, and improving detection efficiency, there is provided a kind of quick timely, automation
Degree is high, preoperative four measurement systems of full-automatic fluorescent immune method of low cost.
In order to solve the above problems, the utility model uses following technical scheme：
A kind of preoperative four measurement systems of full-automatic fluorescent immune method, including for detecting the automatic tester and use of sample
In the kit for containing test paper piece, automatic tester mixes by automatic sampling, dilution, and passes through the test in kit
Test-paper is detected that test paper piece can be respectively used to detect hepatitis b virus s antigen according to detection project
（HBsAg）, surface antibody（HBsAb）, e antigens（HBeAg）, e antibody（HBeAb）, core antibody（HBcAb）, hepatitis C virus
Malicious antibody（HCVAb）, syphilis helicoid antibody（TPAb）And human immune defect virus antibody（HIVAb）；Test paper piece bag
Include on the filter paper for being arranged on two ends, test paper piece wherein one end and the position of filter paper is provided with the plain film of glass fibre, glass
Cellulose membrane is located at the lower section of filter paper close to one end of filter paper, and the other end of glass fibre element film is connected with nitrocellulose filter,
The other end of nitrocellulose filter is connected with the filter paper of the other end on test paper piece.
Further optimization the following is the utility model to such scheme：
Kit be set to eight dress charta boxes, three installed reagents boxes, five installed reagents boxes or single installed reagents box one of which or
Two kinds of combinations, eight dress charta boxes can be respectively used to detect hepatitis b virus s antigen simultaneously（HBsAg）, surface antibody
（HBsAb）, e antigens（HBeAg）, e antibody（HBeAb）, core antibody（HBcAb）, antibody of HCV（HCVAb）, plum
Malicious helicoid antibody（TPAb）, human immune defect virus antibody（HIVAb）Eight.
Further optimization：When kit is three installed reagents boxes and five installed reagents boxes, while coordinating into automatic tester
Using eight detections are completed, three installed reagents boxes are used to detect antibody of HCV simultaneously（HCVAb）, syphilis helicoid antibody
（TPAb）, human immune defect virus antibody（HIVAb）Three, five installed reagents boxes 14 are used to detect hepatitis type B virus table simultaneously
Face antigen（HBsAg）, surface antibody（HBsAb）, e antigens（HBeAg）, e antibody（HBeAb）, core antibody（HBcAb）Five.
Further optimization：When kit is single installed reagents box, single installed reagents box contains the test for detecting eight respectively
Test-paper is detected.
Further optimization：Use is respectively arranged with single installed reagents box, three installed reagents boxes, five installed reagents boxes or eight dress charta boxes
In mixed diluting liquid and the dilution liquid bath of sample.
Further optimization：Detection line and control line are provided with the nitrocellulose filter.
Further optimization：Be provided with the sample module for placing sample in automatic tester, sample module one end it is upper
Side is provided with the dilution for diluted sample, and the position of dilution side is provided with the disposable tip for placing disposable tip
Position on the upside of module, disposable tip module is provided with the diluted cup area for diluted sample.
Further optimization：Position in automatic tester close to sample module one end is provided with the survey for placing kit
The mechanical arm that position in test piece detection module, automatic tester positioned at diluted cup area is provided with for gripping sample presss from both sides original mold
Block.
The utility model is economic low consumption than the advantage that traditional enzyme process luminescence method is determined using fluorescent immune method, it is quick and
When, high degree of automation, medical treatment pollution it is small, qualitative, quantitative all can, meet clinical patient quick detection requirement, realize art
Detected while first four, improve the precision of test, improve the efficiency of detection.
The utility model is described in further detail with reference to the accompanying drawings and examples.
Brief description of the drawings
Accompanying drawing 1 is the structure diagram of the utility model embodiment detection means；
Accompanying drawing 2 is the structural representation of the utility model embodiment test paper piece；
Accompanying drawing 3 is the structural representation that the utility model embodiment list fills test piece；
Accompanying drawing 4 is the structural representation that the utility model embodiment three fills the scraps of paper；
Accompanying drawing 5 is the structural representation that the utility model embodiment five fills the scraps of paper；
Accompanying drawing 6 is the structural representation that the utility model embodiment eight fills the scraps of paper；
Accompanying drawing 7 is the utility model embodiment hepatitis b virus s antigen（HBsAg）Cleaning Principle structural representation；
Accompanying drawing 8 is the utility model embodiment anti-HBs（HBsAb）Cleaning Principle structural representation；
Accompanying drawing 9 is the utility model embodiment anti-HBs（HBsAb）Cleaning Principle structural representation；
Accompanying drawing 10 is the utility model embodiment hepatitis B virus e antigen（HBeAg）Cleaning Principle structural representation；
Accompanying drawing 11 is the utility model embodiment antihepatitis b e antibody（HBeAb）Cleaning Principle structural representation；
Accompanying drawing 12 is the utility model embodiment antihepatitis b e antibody（HBeAb）Cleaning Principle structural representation；
Accompanying drawing 13 is the utility model embodiment anti-HBc（HBcAb）Cleaning Principle structural representation
Figure；
Accompanying drawing 14 is the utility model embodiment antibody of HCV（HCVAb）Cleaning Principle structural representation；
Accompanying drawing 15 is the utility model embodiment syphilis helicoid antibody（TPAb）Cleaning Principle structural representation；
Accompanying drawing 16 is the utility model embodiment human immune defect virus antibody（HIVAb）Cleaning Principle structural representation
Figure；
Accompanying drawing 17 is the structure diagram of embodiment of the present invention detection means；
Accompanying drawing 18 is the structural representation of embodiment of the present invention kit.
In figure：1- automatic testers；2- sample modules；3- dilutions；4- disposable tip modules；5- test piece detection moulds
Block；6- diluted cups area；7- mechanical arms press from both sides egf block；8- test paper pieces；9- filter paper；10- glass fibres element film；11- nitric acid is fine
The plain film of dimension；The mono- installed reagents boxes of 12-；The installed reagents boxes of 13- tri-；The installed reagents boxes of 14- five；15- eight fills charta box；16- dilutes liquid bath.
Embodiment
Embodiment 1, as shown in Figure 1, Figure 2, Figure 6 shows, a kind of full-automatic preoperative four measurement systems of fluorescent immune method, including with
In the automatic tester 1 and kit for containing test paper piece 8 of detection sample, automatic tester 1 by automatic sampling,
Dilution mixing, and detected by the test paper piece 8 in kit, test paper piece 8 can respectively be used according to detection project
In detection hepatitis b virus s antigen（HBsAg）, surface antibody（HBsAb）, e antigens（HBeAg）, e antibody（HBeAb）、
Core antibody（HBcAb）, antibody of HCV（HCVAb）, syphilis helicoid antibody（TPAb）, human immunodeficiency virus
Antibody（HIVAb）；Wherein one end is close to filter paper 9 on filter paper 9 of the test paper piece 8 including being arranged on two ends, test paper piece 8
Position is provided with the plain film 10 of glass fibre, and glass fibre element film 10 is located at the lower section of filter paper 9, glass fibers close to one end of filter paper 9
The other end of the plain film 10 of dimension is connected with nitrocellulose filter 11, another on the other end and test paper piece 8 of nitrocellulose filter 11
The filter paper 9 of one end is connected.
The kit is set to eight dress charta boxes 15, and eight dress charta boxes 15 can be used to detect hepatitis type B virus table simultaneously
Face antigen（HBsAg）, surface antibody（HBsAb）, e antigens（HBeAg）, e antibody（HBeAb）, core antibody（HBcAb）, the third type
Hepatitis virus antibody（HCVAb）, syphilis helicoid antibody（TPAb）, human immune defect virus antibody（HIVAb）Eight.
Detection line and control line are provided with the nitrocellulose filter 11.
The sample module 2 for placing sample is provided with the automatic tester 1, the upside of the one end of sample module 2
The dilution 3 for diluted sample is provided with, the position of the side of dilution 3 is provided with the disposable tip for placing disposable tip
Module 4.
Position in the automatic tester 1 positioned at the upside of disposable tip module 4 is provided with for the dilute of diluted sample
Being provided with Shi Bei areas 6, diluted cup area 6 is used for the mixed uniformly dilution liquid bath 16 of sample and dilution 3.
Position in the automatic tester 1 close to the one end of sample module 2 is provided with the test piece for placing kit
The mechanical arm being provided with detection module 5, automatic tester 1 positioned at the position of disposable tip module 4 for gripping sample is pressed from both sides
Egf block 7, in use, mechanical arm folder egf block 7 is automatically moved to gripping disposable tip at disposable tip module 4, then
Absorption dilution 3 at dilution 3 is moved to, absorption sample at sample module 2 is then moved to, then by the dilution 3 of absorption
It is moved in dilution liquid bath 16, is well mixed with sample, the sample mixed is then drawn by disposable tip and is moved
Drip on the test paper piece 8 in kit, detected simultaneously respectively to test piece detection module 5.
The detection method of preoperative four measurement systems of full-automatic fluorescent immune method, comprises the following steps：
A, as shown in fig. 7, when detection hepatitis b virus s antigen（HBsAg）When, it is pre- on the plain film 10 of glass fibre
It is coated with mouse anti-HBsAg fluorescence monoclonal antibody（HBsAb1）, it is coated with mouse respectively at the detection line and control line of nitrocellulose filter 11 and resists
HBsAg monoclonal antibodies（HBsAb2）And sheep anti-mouse igg；
When the sample is positive, HBsAg and fluorescence monoclonal antibody in sample（HBsAb1）Compound is combined to form, is made in chromatography
Moved forward with lower compound along film strips, by combining to form sandwich complex with pre-coated antibody HBsAb2 during detection line
HBsAb1-HBsAg- HBsAb2, free fluorescence antibody is then combined at control line with sheep anti-mouse igg.
B, as shown in figure 8, when detection anti-HBs（HBsAb）When, detection method 1, in glass fibre
Pre-coated mouse anti-human igg fluorescence antibody on plain film 10, is coated with respectively at the detection line and control line of nitrocellulose filter 11
HBsAg antigens and human IgG antibody；
When the sample is positive, HBsAb combines to form compound with mouse anti-human igg fluorescence antibody in serum, due to layer
The lower compound of analysis effect is moved forward along film strips, by forming mouse anti-human igg fluorescence with pre-coated antigen binding during detection line
Antibody-HBsAb-HBsAg compounds, free mouse anti-human igg fluorescence antibody is combined at control with IgG antibody, is examined by fluorescence
Survey, determine HBsAb contents；
As shown in figure 9, anti-HBs（HBsAb）Detection method 2, it is pre- on the plain film 10 of glass fibre
It is coated with surface antigen（HBsAg）And mouse anti-HBsAg fluorescence antibody（HBsAb2）, the detection line coating on nitrocellulose filter 11
Mouse anti-HBsAg monoclonal antibody（HBsAb1）, sheep anti-mouse igg is coated with control line；
When the sample is positive, the HBsAb in sample can be with HBsAg antigens and mouse anti-HBsAg fluorescence antibody
（HBsAb2）Compound is combined to form, compound is moved forward along film strips under chromatography effect, and during by detection line, compound is not
Can be with mouse anti-HBsAg monoclonal antibody（HBsAb1）With reference to detection line fluorescence intensity is inversely proportional with HBsAb contents；If sample is negative
When, then centre-fills HBsAb1-HBsAg-HBsAb2 fluorescence antibody compounds are formed at detection line.
C, as shown in Figure 10, when detection hepatitis B virus e antigen（HBeAg）When, wrapped in advance on the plain film 10 of glass fibre
By the anti-HBeAg fluorescence antibodies of mouse（HBeAb1）, it is coated with mouse respectively at the detection line and control line of nitrocellulose filter 11 and resists
HBeAg monoclonal antibodies（HBeAb2）And sheep anti-mouse igg；
When the sample is positive, HBeAg and fluorescence monoclonal antibody in sample（HBeAb1）Compound is combined to form, is made in chromatography
Moved forward with lower compound along film strips, by during detection line with pre-coated antibody（HBeAb2）Combine to form sandwich complex
HBeAb1-HBeAg- HBeAb2, free fluorescence antibody is then combined at control line with sheep anti-mouse igg, by fluoroscopic examination, is surveyed
Determine HBeAg contents.
D, as shown in figure 11, when detection antihepatitis b e antibody（HBeAb）When, detection method 1, in glass fibre element
Pre-coated mouse anti-human igg fluorescence antibody on film 10, HBeAg is coated with the detection line and control line of nitrocellulose filter 11 respectively
Antigen and human IgG；
When the sample is positive, HBeAb combines to form compound with mouse anti-human igg fluorescence antibody in serum, in chromatography
The lower compound of effect is moved forward along film strips, is resisted by forming mouse anti-human igg fluorescence with pre-coated antigen binding during detection line
Body-HBeAb- HBeAg compounds, free mouse anti-human igg fluorescence antibody is combined at control line with human IgG antibody, passes through fluorescence
Detection, determines HBeAb contents；
As shown in figure 12, antihepatitis b e antibody（HBeAb）Detection method 2, wrapped in advance on the plain film 10 of glass fibre
By e antigens（HBeAg）And the anti-HBeAg fluorescence antibodies of mouse（HBeAb2）, at the detection line and control line of nitrocellulose filter 11
The anti-HBeAg monoclonal antibodies of mouse are coated with respectively（HBeAb1）And sheep anti-mouse igg；
When the sample is positive, the HBeAb in sample can be with HBeAg antigens and the anti-HBeAg fluorescence antibodies of mouse
（HBeAb2）Compound is combined to form, compound is moved forward along film strips under chromatography effect, and during by detection line, compound is not
It can be combined with detection line HBeAb1, detection line fluorescence intensity is inversely proportional with HBeAb contents；If sample is negative, in detection
Pay rise compound HBeAb1-HBeAg- HBeAb2 fluorescence antibody compounds are formed at line.
E, as shown in figure 13, when detection anti-HBc（HBcAb）When, it is pre- on the plain film 10 of glass fibre
Mouse anti-human igg fluorescence antibody is coated with, cAg is coated with respectively at the detection line and control line of nitrocellulose filter 11
（HBcAg）And human IgG antibody；
When the sample is positive, the HBcAb in serum combines to form compound with mouse anti-human igg fluorescence antibody, in layer
The lower compound of analysis effect is moved forward along film strips, by forming mouse anti-human igg fluorescence with pre-coated antigen binding during detection line
Antibody-HBcAb-HBcAg compounds, free mouse anti-human igg fluorescence antibody is combined at control line with human IgG antibody, by glimmering
Light is detected, determines HBcAb contents.
F, as shown in figure 14, when detection antibody of HCV（HCVAb）When, it is pre-coated on the plain film 10 of glass fibre
Mouse anti-human igg fluorescence antibody, hepatitis C virus antigen is coated with the detection line and control line of nitrocellulose filter 11 respectively
（HCVAg）And human IgG antibody；
When the sample is positive, the HCVAb in serum combines to form compound with mouse anti-human igg fluorescence antibody, in layer
The lower compound of analysis effect is moved forward along film strips, is resisted by forming mouse anti-human igg fluorescence with coated antigen binding during detection line
Body-HCVAb-HCVAg compounds, free mouse anti-human igg fluorescence antibody is combined at control line with human IgG antibody, passes through fluorescence
Detection, determines HCVAb contents.
G, as shown in figure 15, when detection syphilis helicoid antibody（TPAb）When, the pre-coated mouse on the plain film 10 of glass fibre
Anti-human igg fluorescence antibody, Treponema pallidum antigen is coated with the detection line and control line of nitrocellulose filter 11 respectively（TPAg）And people
IgG antibody；
When the sample is positive, the TPAb in serum combines to form immune complex with mouse anti-human igg fluorescence antibody,
The lower compound of chromatography effect is moved forward along film strips, by forming mouse anti-human igg fluorescence with coated antigen binding during detection line
Antibody-TPAb-TPAg compounds, free mouse anti-human igg fluorescence antibody is combined at control line with human IgG antibody, passes through fluorescence
Detection, determines TPAb contents.
H, as shown in figure 16, when detection human immune defect virus antibody（HIVAb）When, it is pre- on the plain film 10 of glass fibre
Mouse anti-human igg fluorescence antibody is coated with, HIV is coated with respectively at the detection line and control line of nitrocellulose filter 11（1+2）Ag and
Human IgG antibody；
When the sample is positive, the HIVAb in serum combines to form compound with mouse anti-human igg fluorescence antibody, in layer
The lower compound of analysis effect is moved forward along film strips, is resisted by forming mouse anti-human igg fluorescence with coated antigen binding during detection line
Body-HIVAb-HIV（1+2）Ag compounds, free mouse anti-human igg fluorescence antibody is combined at control line with human IgG antibody, is passed through
By fluoroscopic examination, HIVAb contents are determined.
Embodiment 2, as shown in Figure 4, Figure 5, in embodiment 1, described kit is three installed reagents boxes 13 and five dress examinations
Agent box 14, and enter simultaneously in automatic tester 1 with the use of eight detections of completion.
The three installed reagents box 13 is used to detect antibody of HCV simultaneously（HCVAb）, syphilis helicoid antibody
（TPAb）, human immune defect virus antibody（HIVAb）Three, five installed reagents boxes 14 are used to detect hepatitis type B virus table simultaneously
Face antigen（HBsAg）, surface antibody（HBsAb）, e antigens（HBeAg）, e antibody（HBeAb）, core antibody（HBcAb）Five.
Embodiment 3, as shown in figure 3, in embodiment 1, described kit is single installed reagents box 12, single installed reagents box 12
The test paper piece 8 for detecting eight is contained respectively, while being detected into automatic tester 1 is interior, detects B-mode respectively
Hepatitis virus surface antigen（HBsAg）, surface antibody（HBsAb）, e antigens（HBeAg）, e antibody（HBeAb）, core antibody
（HBcAb）, antibody of HCV（HCVAb）, syphilis helicoid antibody（TPAb）, human immune defect virus antibody
（HIVAb）.
Embodiment 4, as shown in Figure 17, Figure 18, described a kind of full-automatic preoperative four of fluorescent immune method in embodiment 1
In measurement system, be provided with the sample module 2 for placing sample in the automatic tester 1, one end of sample module 2 it is upper
Side is provided with the dilution 3 for diluted sample, and the position of the upside of dilution 3 is provided with the disposable suction for placing disposable tip
The test piece that position in head module 4, automatic tester 1 close to the one end of sample module 2 is provided with for placing kit is detected
Module 5.
The kit is single installed reagents box 12, three installed reagents boxes 13, five installed reagents boxes 14 or eight dress charta boxes 15, reagent
On box and the dilution liquid bath 16 of mixed diluting liquid 3 and sample is separately provided for, in use, by the dilution 3 and sample of absorption
Originally be moved to dilution liquid bath 16 in, be well mixed, mechanical arm press from both sides egf block 7 drawn by disposable tip dilution 3,
Sample is moved directly at test piece detection module 5, is mixed in the dilution liquid bath 16 on kit, then be drawn to kit
On interior test paper piece 8, detected.
The utility model is economic low consumption than the advantage that traditional enzyme process luminescence method is determined using fluorescent immune method, it is quick and
When, high degree of automation, medical treatment pollution it is small, qualitative, quantitative all can, meet clinical patient quick detection requirement, realize art
Detected while first four, improve the precision of test, improve the efficiency of detection.
Claims (8)
1. a kind of preoperative four measurement systems of full-automatic fluorescent immune method, including for detecting the automatic tester of sample（1）With
For containing test paper piece（8）Kit, it is characterised in that：Automatic tester（1）By automatic sampling, dilution mixing,
And pass through the test paper piece in kit（8）Detected, test paper piece（8）Detection can be respectively used to according to detection project
Hepatitis b virus s antigen（HBsAg）, surface antibody（HBsAb）, e antigens（HBeAg）, e antibody（HBeAb）, core resist
Body（HBcAb）, antibody of HCV（HCVAb）, syphilis helicoid antibody（TPAb）And human immune defect virus antibody
（HIVAb）；Test paper piece（8）Filter paper including being arranged on two ends（9）, test paper piece（8）On wherein one end close to filter paper
（9）Position be provided with the plain film of glass fibre（10）, glass fibre element film（10）Close to filter paper（9）One end be located at filter paper（9）
Lower section, glass fibre element film（10）The other end and nitrocellulose filter（11）Connection, nitrocellulose filter（11）It is another
End and test paper piece（8）The filter paper of the upper other end（9）Connection.
2. a kind of full-automatic preoperative four measurement systems of fluorescent immune method according to claim 1, it is characterised in that：Reagent
Box is set to eight dress charta boxes（15）, can be respectively used to detect hepatitis b virus s antigen simultaneously（HBsAg）, antibody
（HBsAb）, e antigens（HBeAg）, e antibody（HBeAb）, core antibody（HBcAb）, antibody of HCV（HCVAb）, plum
Malicious helicoid antibody（TPAb）, human immune defect virus antibody（HIVAb）Eight.
3. a kind of full-automatic preoperative four measurement systems of fluorescent immune method according to claim 1, it is characterised in that：Reagent
Box is three installed reagents boxes（13）With five installed reagents boxes（14）, and enter automatic tester simultaneously（1）Interior use cooperatively completes eight
Detection, three installed reagents boxes（13）For detecting antibody of HCV simultaneously（HCVAb）, syphilis helicoid antibody（TPAb）、
Human immune defect virus antibody（HIVAb）Three, five installed reagents boxes 14 are used to detect hepatitis b virus s antigen simultaneously
（HBsAg）, surface antibody（HBsAb）, e antigens（HBeAg）, e antibody（HBeAb）, core antibody（HBcAb）Five.
4. a kind of full-automatic preoperative four measurement systems of fluorescent immune method according to claim 1, it is characterised in that：Reagent
Box is single installed reagents box（12）, single installed reagents box（12）The test paper piece for detecting eight is contained respectively（8）, while into
Automatic tester（1）It is interior to be detected.
5. according to a kind of any described full-automatic preoperative four measurement systems of fluorescent immune method of claim 2-4, its feature exists
In：Single installed reagents box（12）, three installed reagents boxes（13）, five installed reagents boxes（14）Or eight dress charta box（15）On be respectively arranged with use
In mixed diluting liquid（3）With the dilution liquid bath of sample（16）.
6. a kind of full-automatic preoperative four measurement systems of fluorescent immune method according to claim 1, it is characterised in that：It is described
Nitrocellulose filter（11）On be provided with detection line and control line.
7. a kind of full-automatic preoperative four measurement systems of fluorescent immune method according to claim 1, it is characterised in that：Automatically
Detector（1）Inside it is provided with the sample module for placing sample（2）, sample module（2）It is provided with the upside of one end for dilute
Release the dilution of sample（3）, dilution（3）The position of side is provided with the disposable tip module for placing disposable tip（4）,
Disposable tip module（4）The position of upside is provided with the diluted cup area for diluted sample（6）.
8. a kind of full-automatic preoperative four measurement systems of fluorescent immune method according to claim 1, it is characterised in that：Automatically
Detector（1）Interior close sample module（2）The position of one end is provided with the test piece detection module for placing kit（5）,
Automatic tester（1）It is interior to be located at disposable tip module（4）The mechanical arm that the position of upside is provided with for gripping sample presss from both sides sample
Module（7）.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201621135595.2U CN206330984U (en) | 2016-10-18 | 2016-10-18 | A kind of preoperative four measurement systems of full-automatic fluorescent immune method |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201621135595.2U CN206330984U (en) | 2016-10-18 | 2016-10-18 | A kind of preoperative four measurement systems of full-automatic fluorescent immune method |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN206330984U true CN206330984U (en) | 2017-07-14 |
Family
ID=59287125
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201621135595.2U Expired - Fee Related CN206330984U (en) | 2016-10-18 | 2016-10-18 | A kind of preoperative four measurement systems of full-automatic fluorescent immune method |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN206330984U (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106596984A (en) * | 2016-10-18 | 2017-04-26 | 秦明 | Full-auto fluorescence immune pre-operation four item assay system and detection method thereof |
-
2016
- 2016-10-18 CN CN201621135595.2U patent/CN206330984U/en not_active Expired - Fee Related
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106596984A (en) * | 2016-10-18 | 2017-04-26 | 秦明 | Full-auto fluorescence immune pre-operation four item assay system and detection method thereof |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN105758835B (en) | A kind of homogeneous immunoassay POCT detection methods and the system using the detection method | |
| CN1161611C (en) | Biosensor | |
| JP2731613B2 (en) | Cartridge for enzyme immunoassay, measuring method and measuring apparatus using the same | |
| JPH07506184A (en) | Automatic continuous random access analysis system | |
| DK151398B (en) | DEVICE FOR IMMUNOLOGICAL DETERMINATION OF ANTIGEN OR ANTIBODIES AND USE OF THIS DEVICE | |
| JPH04501612A (en) | Optical analysis methods, devices for use therein, and assay methods | |
| JP7267211B2 (en) | Sandwich-type assays using the decreasing signal portion of the dose-response curve to measure analytes, such as high-concentration analytes | |
| CN205229167U (en) | Quick quantitative detection AMH's test paper | |
| CN108918865A (en) | Fluorescence immune chromatography test paper bar and reagent card | |
| CN206330984U (en) | A kind of preoperative four measurement systems of full-automatic fluorescent immune method | |
| CN103185797B (en) | Reagent device and method for detecting anti-myeloperoxidase antibody | |
| CN106596984A (en) | Full-auto fluorescence immune pre-operation four item assay system and detection method thereof | |
| US20140011190A1 (en) | Method for performing a rapid test | |
| US20100297778A1 (en) | Conjugate Having Cleavable Linking Agent | |
| CN103185782B (en) | Reagent device and method for detecting anti-mitochondrial antibodies type M2 antibody | |
| CN103185795B (en) | Reagent device and method for detecting EB virus antibody | |
| CN116413444A (en) | Kit for detecting total triiodothyronine content and detection method thereof | |
| CN103185777B (en) | Reagent device and method for detecting anti-Jo-1 antibody | |
| CN103185784B (en) | Reagent device and method for detecting mycoplasma pneumonia antibody | |
| CN206740785U (en) | A kind of quantitative blood and haemocyte filtering sample-adding is used to detect syphilis antibody device | |
| CN103185779A (en) | Reagent device for detecting antinuclear antibody and method thereof | |
| WO2018056700A1 (en) | High-sensitivity rapid diagnostic method of single diagnostic chip including reaction and analysis | |
| CN103185786B (en) | Reagent device and method for detecting anti-double-stranded-DNA antibody | |
| US20220258155A1 (en) | Lateral flow assay with sample adequacy line | |
| JPH01274066A (en) | Enzyme immunoassay method |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20170714 Termination date: 20191018 |
|
| CF01 | Termination of patent right due to non-payment of annual fee |