A kind of ischemic preconditioning therapeutic instrument with vascular health arbitration functions
Technical field
This utility model relates to cardiovascular and cerebrovascular disease prophylactic treatment technical field, particularly relates to a kind of ischemic preconditioning therapeutic instrument with vascular health arbitration functions.
Background technology
The people such as the applicant Ji Xunming of this patent have applied for that in 2007 name is called the patent (application number is 200720173945.9,200710176701.0) of " cerebrovascular and cardiovascular health care therapeutic instrument ".2011, when applicant applies for this type of instrument classification to State Food and Drug Administration, will the instrument called after " ischemic preconditioning training for treatment instrument " of this object be used for, be adopted by State Food and Drug Administration.After this on market like product carrying out applying for the registration of, commercial propaganda, all carry out with this " ischemic preconditioning training for treatment instrument " title.But be through long-term clinical practice and patient's follow-up service discovery, ischemic preconditioning training also has some problems to need perfect.Existing patent and product also solve completely to these problems, are described as follows:
CN202335859U discloses a kind of remote ischemic pre-adaptation instrument, and its technical scheme adopted is in the main body of electric sphygmomanometer, increase by one repeatedly repeatedly timing continue cuff inflation and air releasing device, can short time sustained blockade LBF repeatedly.CN202505429U increases by an induction installation to measure pulse oxygen value on the basis of CN202335859U, until can not record the moment of pulse oxygen value, continue pressurization 200mmHg, inflator pump quits work, and this force value is the pressure set by blocking blood flow.The method in actual use, due to pulse oxygen value be beat according to Ink vessel transfusing at every turn time blood in oxygen content measure oxygen content value, it is approved for not being subject to measured value when vascular compression does not block to normal condition lower arms.When arm straps starts inflation, produce pulse oxygen value when vascular compression is obstructed to arm and can be reduced to zero rapidly, the force value now in arm straps is uncertain, and this pressure-based pressurizes again 200mmHg, the pressure requirements of pre-adaptation training can not be reached, training arm distending pain in practice, can be caused.
The patent documentation of CN203263775U, CN203315307U is pointed out " adopt said structure; this utility model sums up following advantage through repeated tests: the upper limb or the lower limb that repeatedly extrude, loosen human body; promote user blood circulation, produce stress because blocking-up limbs are subject to Brief Ischemic Preconditioning stimulation " in the text.Such design can not meet the requirement of pre-adaptation training method, namely intercepts rapidly the requirement of upper arm blood vessel.Because execute in stressed process to upper arm airbag aeration in pre-adaptation training, putting on pressure on arm first can blocker arm shallow-layer vein blood vessel, namely occlude blood flows back to heart, and arteries does not block in arm deep layer and still continues to arm pumping blood, if larger pressure can not be applied rapidly, to be there is swelling and congestion in finger position, so therapeutic instrument can not be repeatedly extrude.Mentioning air bag in patent can to the training of lower limb, can it is clear that can not implement pre-adaptation training, because this measure can cause lower limb vein thrombus to come off become Great possibility to lower limb from existing document.
CN202801711U discloses a kind of remote ischemic pre-adaptation exercise equipment, the first pressure transducer that this equipment comprises in air pressure adjustment part feeds back air pressure in real time, the contact portion of arm straps and user is provided with the second pressure transducer simultaneously, real-time detection arm straps is to the pressure of user arm, by the dynamic extruding to user arm, user is helped to carry out the instrument of training.This design, not for ischemic preconditioning training method main points, may cause pre-adaptation to train uncomfortable or potential danger.
Applicant Zheng just second-class people and affiliated enterprise thereof has applied for the patent (CN203138608U, CN203139071U, CN102895013A and CN203169547U) of more than one piece about ischemic preconditioning therapeutic instrument successively in 2012; Record in its patent text " Xuanwu Hospital of Capital University of Medical Science adopts a kind of external secured physical non-invasive methods, is exactly distal ischemia pre-adaptation Therapeutic Method ", its utility model object is exactly for ischemic preconditioning training uses; Mention again in patent " industry does not utilize this principle to carry out the research and development of medical apparatus and instruments at present, how to make full use of this principle and studies corresponding medical apparatus and instruments and become the problem of pendulum in face of people " simultaneously.In fact, the domestic initiation research team that Xuanwu Hospital of Capital University of Medical Science is trained as ischemic preconditioning, the pre-adaptation therapeutic instrument successfully developed in 2008, and through continual research for many years, through the improvement of number for product, serve thousands so far.The weak point of the ischemic preconditioning therapeutic instrument involved by above-mentioned patent is its Shortcomings in clinical practice, existing defects in structure, cause patient to occur the senses of discomfort such as finger position swelling and congestion in pre-adaptation training process, the reason caused is that inner air path structural design is unreasonable; In addition, also incomplete place is there is in inflator pump setting, patient's experience, not for the adjustment that ischemic preconditioning training method main points are carried out functionally, be only used to the function simply realizing ischemic preconditioning treatment, and the object reaching ischemic preconditioning treatment that can not be real.
To sum up, existing distal ischemia pre-adaptation therapeutic equipments mostly is the improvement carried out on sphygomanometer basis, although its technical scheme provided can realize this function substantially according to the requirement of remote ischemic pre-adaptation training.But it is take patient at least to adhere to just having therapeutic effect in more than three months that ischemic preconditioning training really realizes therapeutic effect, and user adheres to training the object that just can reach prevention for a long time.Part instrument is accuracy when realizing blood pressure measurement in addition, limits the power of air pump, although such structure causes instrument can realize pre-adaptation training function, can not realize the training of effective pre-adaptation, more cannot reach good therapeutic effect.
At present, between upper arm difference of blood pressure (inter-arm blood pressure difference, IAD) diagnostic criteria: IAD >=10mmHg as the standard of exception.But systolic pressure IAD (sIAD) is divided into two-stage by some researchs: one-level sIAD >=10mmHg, secondary sIAD >=20mmHg.And diastolic pressure IAD (dIAD) >=10mmHg.If high IAD appears in patient, being then prompted its peripheral vascular disease (peripheral vascular disease, PVD) is exist.
Current achievement in research shows, in the 386 routine patients suspecting coronary heart disease, 27 examples (7%) the patient myocardial ischemia-area of sIAD >=15mmHg is larger.The IAD patient of 63% is diagnosable is coronary heart disease, and 83% is wherein multi-vessel lesion.Therefore IAD can accusing of as Coronary Artery Lesions.
At present, external most scholar uses the title of difference of blood pressure between upper arm (inter-arm blood pressure difference, IAD).It is generally acknowledged that the IAD of normal person's systolic pressure and diastolic pressure all should be less than 10mmHg at present.Only there are 2 correlational studyes abroad at present.A research observation 83 example follows up a case by regular visits to 5.6 years; Show, the average Event-free survival of dIAD person (mean event-free survival) is 3.3 years, but not dIAD group is 5.0 years (P<0.0001).Another observes 421 routine patient 7 years.Two researchs confirm that IAD patient's cardiovascular and cerebrovascular disease event increases.After correcting the factor such as average systolic and chronic kidney disease, sIAD often differs 10mmHg, and mortality risk ratio is 1.24 (95% credibility interval is 1.01-1.52).U.S.'s perspective study shows, if the blood pressure difference >=20/10mmHg between patient's both arms, the sickness rate of cardiovascular diseases and mortality rate will significantly increase.
The people such as Clark CE have delivered paper on famous medical journals " lancet ", by the analysis to medical literature in the past, display Inter arm difference can to a certain extent can the risk of predicting cardiovascular disease, and relevant research report enumerates 28 sections of relevant papers.According to this report, evidence suggests, if IAD reaches 10mmHg, peripheral vascular disease to be suffered from; If IAD is at more than 15mmHg, just have the risk of very large trouble peripheral vascular disease (i.e. narrowed blood vessels and sclerosis), also can represent that someone suffers from the cerebrovascular disease be pre-existing in addition.This is because IAD is excessive, the risk that the blood flowing to both legs both feet is reduced increases by 2.5 times, make the risk flowing the minimizing of cerebripetal blood increase by 1.6 times, the risk from cardiovascular disease death improves 70%, and the risk of other reasons disease death improves 60%.If can judge vascular health situation according to the numerical value of the IAD measured, and early point discovery peripheral vascular disease carry out blood pressure lowering and cholesterol and smoking cessation, contribute to reducing dead risk.
Utility model content
The purpose of this utility model is the technological deficiency for existing in prior art, and provides a kind of ischemic preconditioning therapeutic instrument with vascular health arbitration functions, and it has the several functions that the judgement of vascular health situation, both arms measuring blood pressure and ischemic preconditioning are trained.
The technical scheme adopted for realizing the purpose of this utility model is: a kind of ischemic preconditioning therapeutic instrument with vascular health arbitration functions, comprise housing, arm straps, the button be arranged on housing, display screen and control circuit, it is characterized in that: the left and right sides of described housing is respectively arranged with two for connecting the arm straps jack of arm straps; Gas circuit structure is provided with in described housing; Described gas circuit structure comprises five-way device, and described five-way device is connected to left air pump, right air pump, left electromagnetic valve, right electromagnetic valve and gas bleeder valve; Described left electromagnetic valve is connected with left arm and ushers to seat, and is provided with left pressure transducer between the two; Described right electromagnetic valve is connected with right arm and ushers to seat, and is provided with right pressure transducer between the two; Described left arm is usherd to seat, right arm is usherd to seat is connected with the arm straps jack of described housing both sides respectively.
Described control circuit comprises microprocessor, A/D conversion chip, clock/calendar chip, memory chip and power circuit; Described microprocessor is connected with GPRS module.
Concrete, described GPRS module comprises GPRS transceiving chip, sim card slot, power amplifier chip and antenna; Described GPRS transceiving chip is provided with RxD port and TxD port, and is connected with described microprocessor by both; Described GPRS transceiving chip is also connected with described sim card slot and power amplifier chip respectively, and described power amplifier chip is connected with described antenna.
GPRS transceiving chip is connected with the serial communication interface of microprocessor by RxD with TxD port, reads the data in described memory chip, after completing training or blood pressure measurement, data is sent it back background server at every turn.For avoiding transceiving data to lose, after data signal being amplified by described power amplification circuit, then through antenna transmission and reception, repeating the data before sending shutdown last time during each start, doing contrast verification.
Above-mentioned ischemic preconditioning training for treatment instrument carries out the method for vascular health situation judgement, comprises the following steps:
(1) two arm straps are worn on left and right arm by user respectively, usherd to seat respectively by the jack of two arm straps, right arm ushers to seat and be connected with left arm;
(2) start ischemic preconditioning training for treatment instrument, first first time blood pressure measurement is started to left arm pressurization, according to oscillographic method principle, calculate systolic pressure, diastolic pressure and pulse that left arm is measured, measure and terminate rear first time measurement result and will be stored by automatic Memory; Speak in measuring process, that the abnormal measurement result that all will cause occurs for action and arm straps is abnormal, abnormal data will not remembered, and measures and will restart, until obtain correct measurement result;
(3) then Automatic Program carries out first time blood pressure measurement to right arm, calculates systolic pressure that left arm measures, diastolic pressure and pulse, measures to terminate rear first time measurement result and will be stored by automatic Memory;
(4), after effectively measuring in triplicate, screen is by the difference of the left and right arm measure systolic pressure of display, diastolic pressure meansigma methods;
(5) difference recorded by step (4) carries out the judgement of vascular health situation.
Data shows, and it is generally acknowledged that the systolic pressure difference of normal person's both arms and diastolic pressure difference all should be less than 10mmHg.If difference of blood pressure (inter-arm blood pressure difference, IAD) reaches 10mmHg between upper arm, peripheral vascular disease may be suffered from.
Compared with prior art, the beneficial effects of the utility model are:
(1) pressure of arm straps air bag can be reached setup pressure value by gas circuit structure of the present utility model at short notice rapidly, makes patient effectively alleviate sense of discomfort and pain sensation in use, is applicable to carrying out training for a long time and uses;
(2) this utility model not only achieve any switching laws left and right arms carry out separately ischemic preconditioning training and both arms carry out pre-adaptation training simultaneously, meet clinical to ischemic preconditioning training requirement, but also have vascular health situation judgement function; The vascular health degree of the ischemic preconditioning therapeutic instrument that patient can be provided by this utility model to self judges.
Accompanying drawing explanation
Figure 1 shows that the surface structure schematic diagram of ischemic preconditioning training for treatment instrument;
Figure 2 shows that the gas circuit structure schematic diagram of ischemic preconditioning training for treatment instrument;
Figure 3 shows that ischemic preconditioning training for treatment instrument internal circuit configuration connection layout.
Detailed description of the invention
Below in conjunction with specific embodiment, this utility model is described in further detail.Should be appreciated that specific embodiment described herein only in order to explain this utility model, and be not used in restriction this utility model.
Embodiment:
Be illustrated in figure 1 a kind of ischemic preconditioning therapeutic instrument with vascular health arbitration functions, comprise housing 1, arm straps, the button be arranged on housing, display screen 2 and control circuit; The left and right sides of described housing 1 is respectively arranged with two for connecting the arm straps jack 3 of arm straps.
Gas circuit structure 4 is provided with, as shown in Figure 2 in described housing 1; Described gas circuit structure 4 comprises five-way device 43, and described five-way device is connected to left air pump 41, right air pump 42, left electromagnetic valve 44, right electromagnetic valve 45 and gas bleeder valve 48; Described left electromagnetic valve 44 is connected with left arm and ushers to seat 46, is provided with left pressure transducer 491 between the two; Described right electromagnetic valve 45 is connected with right arm and ushers to seat 47, is provided with right pressure transducer 492 between the two; Described left arm ushers to seat 46, right arm is usherd to seat 47 is connected with the arm straps jack 3 of described housing 1 both sides respectively.
The pressure of arm straps air bag can be reached setup pressure value by above-mentioned gas circuit structure at short notice rapidly; Ischemic preconditioning therapeutic instruments more of the prior art are what to improve on the basis of sphygomanometer mostly, even for realizing accuracy during blood pressure measurement, one definite limitation is made to the power of air pump, although so just cause it to meet the function of pre-adaptation training, effective pre-adaptation training effect can not be reached.
As shown in Figure 3, described control circuit comprises microprocessor, A/D conversion chip, clock/calendar chip, memory chip and power circuit; Described microprocessor is also connected with GPRS module.
Concrete, described GPRS module comprises GPRS transceiving chip, sim card slot, power amplifier chip and antenna; Described GPRS transceiving chip is provided with RxD port and TxD port, and is connected with described microprocessor by both; Described GPRS transceiving chip is also connected with described sim card slot and power amplifier chip respectively, and described power amplifier chip is connected with described antenna.
GPRS transceiving chip is provided with RxD port and TxD port; Be connected with the serial communication interface of microprocessor by RxD with TxD port, read the data in described memory chip, after completing training or blood pressure measurement, send it back background server at every turn.For avoiding transceiving data to lose, after data signal is amplified by described power amplification circuit, then through antenna assembly transmission and reception, during each start, repeating the data before sending shutdown last time, doing the contrast verification of transceiving data.
Integrated GPRS module, makes measurement, training and fault data can be transferred to server database by real-time radio; The effect of carrying out pre-adaptation training clinically depends on the training adhered to for a long time, depends on the collection of long term data, and GPRS module, by attenuating loss of data or invalid probability, improves effectiveness and the success rate of ischemic preconditioning training; In addition, doctor can also carry out information pushing by GPRS module and patient, better carries out training and treating to instruct patient.
Above-mentioned ischemic preconditioning training for treatment instrument carries out the method for vascular health situation judgement, comprises the following steps:
(1) two arm straps are worn on left and right arm by user respectively, the jack of two arm straps is usherd to seat respectively 46 with left arm, right arm ushers to seat and 47 to be connected;
(2) start ischemic preconditioning training for treatment instrument, first first time blood pressure measurement is started to left arm pressurization, according to oscillographic method principle, calculate systolic pressure, diastolic pressure and pulse that left arm is measured, measure and terminate rear first time measurement result and will be stored by automatic Memory; Speak in measuring process, that the abnormal measurement result that all will cause occurs for action and arm straps is abnormal, abnormal data will not remembered, and measures and will restart, until obtain correct measurement result;
(3) then Automatic Program carries out first time blood pressure measurement to right arm, calculates systolic pressure that left arm measures, diastolic pressure and pulse, measures to terminate rear first time measurement result and will be stored by automatic Memory;
(4), after effectively measuring in triplicate, screen is by the difference of the left and right arm measure systolic pressure of display, diastolic pressure meansigma methods;
(5) difference recorded by step (4) carries out the judgement of vascular health situation.Data shows, and it is generally acknowledged that the systolic pressure difference of normal person's both arms and diastolic pressure difference all should be less than 10mmHg.If difference of blood pressure (inter-arm blood pressure difference, IAD) reaches 10mmHg between upper arm, peripheral vascular disease may be suffered from.
In conjunction with content above, this utility model not only achieve any switching laws left and right arms carry out separately ischemic preconditioning training and both arms carry out pre-adaptation training simultaneously, meet the clinical requirement to ischemic preconditioning training, but also there is the function of vascular health situation judgement.
In addition, can also carry out blood pressure measurement by above-mentioned ischemic preconditioning training for treatment instrument, concrete comprises the following steps:
(1) when left arm Measure blood pressure, be first worn on left arm by arm straps, left air pump 41 starts inflation, and open left electromagnetic valve 44 to left arm airbag aeration, right electromagnetic valve 45 cuts out right arm band gas circuit simultaneously; When adopting oscillographic method to measure user blood pressure in real time, gas bleeder valve 48 is at the uniform velocity exitted, and the pressure oscillation ripple that left pressure transducer 491 detects gas in arm straps is in real time converted to the signal of telecommunication, calculates systolic pressure, diastolic pressure and pulse after filtering by control circuit; After measurement completes, gas bleeder valve 48 will open venting, and blood pressure,left arm is measured and terminated;
(2) when right arm Measure blood pressure, left air pump 41 starts inflation, and right electromagnetic valve 45 is opened to right arm airbag aeration, and left electromagnetic valve 44 cuts out left arm band gas circuit simultaneously; When adopting oscillographic method to measure user blood pressure in real time, gas bleeder valve 48 is at the uniform velocity exitted, and the pressure oscillation ripple that right pressure transducer 492 detects gas in arm straps is in real time converted to the signal of telecommunication, calculates systolic pressure, diastolic pressure and pulse after filtering by control circuit; After measurement completes, gas bleeder valve 48 will open venting, and blood pressure,right arm is measured and terminated;
In addition, ischemic preconditioning training can also be carried out by above-mentioned ischemic preconditioning training for treatment instrument.The mechanism of ischemic preconditioning training, it is exactly the upper limbs blood flow being blocked patient by recurrence interval, thus excite when injected organism tissue cell anti-/ resistance to ischemia ability, transfer body, organ or tissue survive and ability to work under anoxic conditions, for the prevention and therapy of cardiovascular and cerebrovascular disease, reduce altitude sickness, promote memory, improve sleep quality.Concrete, carry out pre-adaptation training by above-mentioned ischemic preconditioning training for treatment instrument and comprise the following steps:
(1) when doing pre-adaptation training to left arm, left air pump 41 and right air pump 42 start simultaneously, and right electromagnetic valve 45 cuts out to block right arm gas circuit, and gas bleeder valve 48 cuts out; Left electromagnetic valve 44 is opened, the rapid inflating pressure of left arm arm straps air bag, and left pressure transducer 491 detects that pressure signal feeds back to control circuit in real time, and after in arm straps, pressure arrives setup pressure value, control circuit closes down left air pump 41 and right air pump 42 simultaneously.
In gas replenishment process, control circuit will calculate the time arrived needed for setting pressure, if ischemic preconditioning instruction treats instrument inflationtime exceeded the time arrived needed for setting pressure, stopping is inflated by left air pump 41 and right air pump 42, gas bleeder valve 48 is by automatic deflation to zero pressure simultaneously, then restarts air-pump inflating; In the training process, when intracapsular pressure drops to the low limit value of ischemic preconditioning training for treatment instrument, control circuit starts left air pump 41 and supplements air pressure.In whole training process, left pressure transducer 491 will monitor the pressure change of gas circuit all the time, and feed back to control circuit in time, make adjustment in time.Control circuit will do corresponding control according to preset program to pressing time, release time, frequency of training.
(2) when doing pre-adaptation training to right arm, left air pump 41 and right air pump 42 start simultaneously, and left electromagnetic valve 44 cuts out, and block left arm gas circuit, gas bleeder valve 48 cuts out; Right electromagnetic valve 45 is opened, the rapid inflating pressure of right arm arm straps air bag, and right pressure transducer 492 detects that pressure signal feeds back to control circuit in real time, and after in arm straps, pressure arrives setup pressure value, control circuit closes down left air pump 41 and right air pump 42 simultaneously;
In gas replenishment process control circuit by calculate arrive needed for setting pressure time, if ischemic preconditioning therapeutic instrument inflationtime has exceeded the time arrived needed for setting pressure, stopping is inflated by left air pump 41 and right air pump 42, gas bleeder valve 48 is by automatic deflation to zero pressure simultaneously, then restarts air-pump inflating; In the training process, when intracapsular pressure drops to the low limit value of ischemic preconditioning training for treatment instrument, control circuit starts left air pump 41 and supplements air pressure.In whole training process, right pressure transducer 492 will monitor the pressure change of gas circuit all the time, and feed back to control circuit in time, make adjustment in time.Control circuit will do corresponding control according to preset program to pressing time, release time, frequency of training.
(3) when both arms do pre-adaptation training simultaneously, left air pump 41 and right air pump 42 start simultaneously, and left electromagnetic valve 44 and right electromagnetic valve 45 are opened simultaneously, and gas bleeder valve 48 cuts out, and gas circuit closes; The rapid inflating pressure of both arms arm straps air bag, in arm straps, pressure arrives after setup pressure value, and control circuit closes down left air pump 41 and right air pump 42 simultaneously, and constant voltage keeps after 3-5 minute, automatic deflation rest 3-5 minute, then inflating pressure again.Repeat aforesaid operations 5 times, namely complete pre-adaptation training.
The above is only preferred implementation of the present utility model; it should be noted that; for those skilled in the art; under the prerequisite not departing from this utility model principle; can also make some improvements and modifications, these improvements and modifications also should be considered as protection domain of the present utility model.