CN1911366A - Traditional Chinese medicine composition for treating hysteromyoma - Google Patents

Abstract

A Chinese medicine for treating hysteromyoma, weakness, abdominal pain with straining, abdominal distension, menoxenia, menalgia, etc and its preparing process are disclosed.

Description

A kind of Chinese medicine composition that is used for hysteromyoma

Technical field:

The present invention relates to a kind of Chinese medicine composition and preparation technology thereof, particularly a kind of to be used for limbs weak, and the soreness of waist is weighed down heavy, disease such as menoxenia due to the hysteromyoma, dysmenorrhea and to the prescription and the preparation technology thereof of climacteric, deficiency of spleen-YANG and kidneyYANG finding excessive menstruation.

Background technology:

Limbs are weak, and the soreness of waist is weighed down heavy, disease such as menoxenia due to the hysteromyoma, dysmenorrhea and be clinically to see that symptom, the traditional Chinese medical science often take the means of warming and recuperating the kidney-YANG, the broken knot of eliminate indigestion that it is treated to climacteric, deficiency of spleen-YANG and kidneyYANG finding excessive menstruation more, and evident in efficacy.But shortcomings such as in the practice, onset is slow because many Chinese medicines have, the course of treatment is long have a strong impact on its clinical practice.

Chinese medicine composition of the present invention can collect the elite and thick the putting of medicine, is easy to dissolving and absorption, and curative effect is fast, and administration time is short, and therefore, curative effect is better.

The purpose of this invention is to provide that a kind of to be used for limbs weak, the soreness of waist is weighed down heavy, disease such as menoxenia, dysmenorrhea reaches pure Chinese medicine composition and the multiple appropriate formulation thereof to climacteric, deficiency of spleen-YANG and kidneyYANG finding excessive menstruation due to the hysteromyoma, and said preparation is rapid-action, evident in efficacy, is worthy of popularization.

Summary of the invention:

The present invention relates to a kind of prescription and preparation technology thereof of Chinese medicine preparation, it is characterized in that, the preparation of per 1000 dosage units in basic side is prepared from by following proportion raw material:

50～200 parts of 100～400 parts of Radix Morindae Officinaliss of 100～400 parts of Herba Epimedii of the Radix Astragali

25～100 parts of 50～200 parts of Bulbus Fritillariae Thunbergiis of 25～100 portions of Rhizoma Cyperis of Rhizoma Curculiginis

25～100 parts of 50～200 parts of stir-baked SQUAMA MANITISs of Radix Angelicae Sinensis.

Preferably:

100 parts of 200 parts of Radix Morindae Officinaliss of 200 parts of Herba Epimedii of the Radix Astragali

50 parts of 100 parts of Bulbus Fritillariae Thunbergiis of 50 portions of Rhizoma Cyperis of Rhizoma Curculiginis

50 parts of 100 parts of stir-baked SQUAMA MANITISs of Radix Angelicae Sinensis.

The preparation of per 1000 dosage units of the present invention side of deriving a is prepared from by following proportion raw material:

50～200 parts of 100～400 parts of Radix Morindae Officinaliss of 100～400 parts of Herba Epimedii of the Radix Astragali

25～100 parts of 50～200 parts of Bulbus Fritillariae Thunbergiis of 25～100 portions of Rhizoma Cyperis of Rhizoma Curculiginis

50～200 parts of 25～100 parts of Radixs Linderae of 50～200 parts of stir-baked SQUAMA MANITISs of Radix Angelicae Sinensis

25～100 parts of the Radixs Angelicae Dahuricae.

Preferably:

100 parts of 200 parts of Radix Morindae Officinaliss of 200 parts of Herba Epimedii of the Radix Astragali

50 parts of 100 parts of Bulbus Fritillariae Thunbergiis of 50 portions of Rhizoma Cyperis of Rhizoma Curculiginis

100 parts of 50 parts of Radixs Linderae of 100 parts of stir-baked SQUAMA MANITISs of Radix Angelicae Sinensis

50 parts of the Radixs Angelicae Dahuricae.

The preparation of per 1000 dosage units of the present invention side of deriving b is prepared from by following proportion raw material:

50～200 parts of 100～400 parts of Radix Morindae Officinaliss of 100～400 parts of Herba Epimedii of the Radix Astragali

25～100 parts of 50～200 parts of Bulbus Fritillariae Thunbergiis of 25～100 portions of Rhizoma Cyperis of Rhizoma Curculiginis

56～224 parts of 25～100 parts of Semen Litchis of 50～200 parts of stir-baked SQUAMA MANITISs of Radix Angelicae Sinensis

8.5～34 parts of Herba Asaris.

Preferably:

100 parts of 200 parts of Radix Morindae Officinaliss of 200 parts of Herba Epimedii of the Radix Astragali

50 parts of 100 parts of Bulbus Fritillariae Thunbergiis of 50 portions of Rhizoma Cyperis of Rhizoma Curculiginis

112 parts of 50 parts of Semen Litchis of 100 parts of stir-baked SQUAMA MANITISs of Radix Angelicae Sinensis

17 parts of Herba Asaris.

In more than forming, the weight of medicine is calculated with crude drug, and per 1 part can be 1 gram, also can be kilogram or ton, if be unit with gram, this prescription composition can be made into 1000 doses of pharmaceutical preparatioies.Described 1000 doses of fingers, the final drug preparation of making, as make granule 1000g etc., also can make big packing as granule, as 100～500 bags, specifically can be 100 bags, 125 bags, 200 bags, 250 bags, 500 bags etc., every bag can be used as taking dose 1 time.

More than form, can be made into the preparation of 50～1000 taking doses,, make 125 bags, take 1～2 bag at every turn, can take altogether 62.5～125 times as granule.

More than form to be by weight as proportioning, when producing, can increase or reduce according to corresponding proportion, as large-scale production can be unit with the kilogram, or be unit with the ton, small-scale production can be unit with the milligram also, weight can increase or reduce, but the constant rate of the raw medicinal herbs weight proportion between each composition.

The raw material of Chinese medicine of said ratio extracts processing through new technology of the present invention, obtain the active constituents of medicine of preparation of the present invention, add suitable excipient as required and make suitable medicinal any dosage form, said preparation can be multiple suitable dosage forms such as capsule, granule, tablet, powder.

The specific embodiment:

Further specify the present invention by the following examples, include but not limited to the following example.

Embodiment 1:

The preparation method of granule of the present invention:

Prescription:

Radix Astragali 200g Herba Epimedii 200g Radix Morindae Officinalis 100g

Rhizoma Curculiginis 50g Rhizoma Cyperi 100g Bulbus Fritillariae Thunbergii 50g

Radix Angelicae Sinensis 100g stir-baked SQUAMA MANITIS 50g

Make 1000g

Preparation method:

(1) get stir-baked SQUAMA MANITIS, the Radix Angelicae Dahuricae, Bulbus Fritillariae Thunbergii medical material and directly be ground into fine powder, standby;

(2) get the residue medical material, extracting in water 2 times, amount of water are 8 times, each extraction time is 1.5 hours, and merge extractive liquid, filters, filtrate decompression is concentrated into the clear paste of relative density 1.18～1.22 (50 ℃ of surveys), put coldly, add ethanol and make and contain alcohol amount and reach 50～80%, stir evenly, left standstill 24 hours, get supernatant and reclaim ethanol to be concentrated into relative density be 1.15～1.30 (50), drying, water extract;

(3) above active component is merged mixing, add aspartame 5.0g, dextrin 200.0g, granulate, drying sprays into essence 5.0g, promptly gets granule 1000g.

Embodiment 2:

The preparation method of capsule of the present invention:

Prescription:

Radix Astragali 200g Herba Epimedii 200g Radix Morindae Officinalis 100g

Rhizoma Curculiginis 50g Rhizoma Cyperi 100g Bulbus Fritillariae Thunbergii 50g

Radix Angelicae Sinensis 100g stir-baked SQUAMA MANITIS 50g

Make 1000

Preparation method:

(1) get stir-baked SQUAMA MANITIS, the Radix Angelicae Dahuricae, Bulbus Fritillariae Thunbergii medical material and directly be ground into fine powder, standby;

(2) get the residue medical material, extracting in water 2 times, amount of water are 8 times, each extraction time is 1.5 hours, and merge extractive liquid, filters, filtrate decompression is concentrated into the clear paste of relative density 1.18～1.22 (50 ℃ of surveys), put coldly, add ethanol and make and contain alcohol amount and reach 50～80%, stir evenly, left standstill 24 hours, get supernatant and reclaim ethanol to be concentrated into relative density be 1.15～1.30 (50), drying, water extract;

(3) above active component is merged mixing, dry, be made into 1000 of capsules according to the pharmaceutics routine techniques.

Embodiment 3:

The preparation method of tablet of the present invention:

Prescription:

Radix Astragali 200g Herba Epimedii 200g Radix Morindae Officinalis 100g

Rhizoma Curculiginis 50g Rhizoma Cyperi 100g Bulbus Fritillariae Thunbergii 50g

Radix Angelicae Sinensis 100g stir-baked SQUAMA MANITIS 50g

Make 1000

Preparation method:

(1) get stir-baked SQUAMA MANITIS, the Radix Angelicae Dahuricae, Bulbus Fritillariae Thunbergii medical material and directly be ground into fine powder, standby;

(2) get the residue medical material, extracting in water 2 times, amount of water are 8 times, each extraction time is 1.5 hours, and merge extractive liquid, filters, filtrate decompression is concentrated into the clear paste of relative density 1.18～1.22 (50 ℃ of surveys), put coldly, add ethanol and make and contain alcohol amount and reach 50～80%, stir evenly, left standstill 24 hours, get supernatant and reclaim ethanol to be concentrated into relative density be 1.15～1.30 (50), drying, water extract;

(3) above active component is merged mixing, dry, be made into 1000 in tablet according to the pharmaceutics routine techniques.

Claims (8)

1, a kind of Chinese medicine preparation for the treatment of hysteromyoma is characterized in that: according to weight proportion, it is by the Radix Astragali 100～400, Herba Epimedii 100～400, Radix Morindae Officinalis 50～200, Rhizoma Curculiginis 25～100, Rhizoma Cyperi 50～200, Bulbus Fritillariae Thunbergii 25～100, Radix Angelicae Sinensis 50～200, stir-baked SQUAMA MANITIS 25～100 is for square substantially; Or be equipped with 50～200 parts of the Radixs Linderae, 25～100 parts of the Radixs Angelicae Dahuricae; Or being equipped with 56～224 parts of Semen Litchis, 8.5～34 parts of generation sides of deriving of Herba Asari are made.

2, the Chinese medicine preparation of claim 1 is characterized in that, described basic side's proportioning is: 200 parts of the Radixs Astragali, 200 parts of Herba Epimedii, 100 parts of Radix Morindae Officinaliss, 50 parts of Rhizoma Curculiginises, 100 parts of Rhizoma Cyperis, 50 parts of Bulbus Fritillariae Thunbergiis, 100 parts of Radix Angelicae Sinensis, 50 parts of stir-baked SQUAMA MANITISs.

3, the Chinese medicine preparation of claim 1 is characterized in that, the proportioning of the described side of deriving is:

The basic side of A adds the Radix Linderae, the Radix Angelicae Dahuricae;

The basic side of B adds Semen Litchi, Herba Asari.

4, the Chinese medicine preparation of claim 1 is characterized in that, is described raw material of Chinese medicine is extracted processing, obtains active component, adds suitable adjuvant as required, makes clinical needed dosage form with the galenic pharmacy routine techniques.

5, the Chinese medicine preparation of claim 4 is characterized in that:

The preparation process of described granule is as follows: with above-mentioned extract obtained, add a certain amount of filler, correctives, lubricant, granulate, promptly get granule;

The preparation method of tablet is as follows: with above-mentioned extract obtained, adds a certain amount of filler, correctives, lubricant, disintegrating agent, granulates, and drying, tabletting promptly gets tablet.

6, the Chinese medicine preparation of claim 5 is characterized in that:

Described filler is selected from one or more the mixture in lactose, sucrose, dextrin, starch, microcrystalline Cellulose, mannitol, pregelatinized Starch, sorbitol, the xylitol etc.;

Described correctives one of is selected from Rhizoma et radix valerianae, Fructus Pruni pseudocerasi, Fructus Vitis viniferae, Fructus Citri tangerinae, Fructus Citri Limoniae, Herba Menthae, Fructus Fragariae Ananssae, Fructus Musae, Fructus Ananadis comosi, honey peach essence, maltose alcohol, saccharin sodium, protein sugar, sucrose, aspartame, the stevioside or wherein several mixture;

Suitable lubricant comprises wherein one or more such as magnesium stearate, Pulvis Talci, micropowder silica gel.

7, the preparation method of claim 6 is characterized in that: the prescription of the preparation of making is respectively:

The a Radix Astragali, Herba Epimedii, Radix Morindae Officinalis, Rhizoma Curculiginis, Rhizoma Cyperi, Bulbus Fritillariae Thunbergii, Radix Angelicae Sinensis, stir-baked SQUAMA MANITIS;

The b Radix Astragali, Herba Epimedii, Radix Morindae Officinalis, Rhizoma Curculiginis, Rhizoma Cyperi, Bulbus Fritillariae Thunbergii, Radix Angelicae Sinensis, stir-baked SQUAMA MANITIS, the Radix Linderae, the Radix Angelicae Dahuricae;

The c Radix Astragali, Herba Epimedii, Radix Morindae Officinalis, Rhizoma Curculiginis, Rhizoma Cyperi, Bulbus Fritillariae Thunbergii, Radix Angelicae Sinensis, stir-baked SQUAMA MANITIS, Semen Litchi, Herba Asari.

8, the Chinese medicine preparation of claim 1 is weak at preparation treatment limbs, and the soreness of waist is weighed down heavy, disease such as menoxenia due to the hysteromyoma, dysmenorrhea and to the application in the medicine of climacteric, deficiency of spleen-YANG and kidneyYANG finding excessive menstruation.