CN1839981A - Gynecological inflammation resisting dispersion tablet and its preparation method - Google Patents
Gynecological inflammation resisting dispersion tablet and its preparation method Download PDFInfo
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- CN1839981A CN1839981A CN 200610032657 CN200610032657A CN1839981A CN 1839981 A CN1839981 A CN 1839981A CN 200610032657 CN200610032657 CN 200610032657 CN 200610032657 A CN200610032657 A CN 200610032657A CN 1839981 A CN1839981 A CN 1839981A
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- gynecological inflammation
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Abstract
Disclosed is a dispersible tablet for treating pelvic inflammation and is preparing process, wherein the tablet is prepared from right amount of flavescent sophora root, corktree bark, adzuki bean, capsule of weeping forsythia and motherwort through the steps of water boiling, condensating to thick grease, and charging right amount of auxiliary materials.
Description
Affiliated technical field:
The invention belongs to pharmaceutical, it has blood circulation promoting and blood stasis dispelling, the effect of heat clearing and damp drying, and clinical damp heat downward flowing type pelvic inflammatory disease, vaginitis, the chronic cervicitis of being used for the treatment of, disease is seen diseases such as leucorrhea with red and white discharge, pudendal pruritus, hemorrhage, dysmenorrhea.Be a kind of gynecological inflammation resisting dispersion tablet and preparation method specifically.
Background technology:
At present, also do not find to have similar products and preparation method thereof on the market.
Summary of the invention:
The technical solution used in the present invention is: gynecological inflammation resisting dispersion tablet of the present invention and preparation method, it is characterized in that: gynecological inflammation resisting dispersion tablet method for making, the main component of gynecological inflammation resisting dispersion tablet is by Radix Sophorae Flavescentis, Herba Polygoni cymosi, Cortex Phellodendri, Fructus Forsythiae, Herba Leonuri, Semen Phaseoli, Folium Artemisiae Argyi, Radix Angelicae Sinensis, the Radix Linderae.More than nine the flavor, get part Radix Sophorae Flavescentis, Cortex Phellodendri, Semen Phaseoli, Fructus Forsythiae, be ground into fine powder, sieve, standby.The five tastes such as residue decoct with water secondary, 2 hours for the first time, 1 hour for the second time, collecting decoction filtered, filtrate is concentrated into the thick paste that relative density is 1.31～1.35 (60～80 ℃), add above-mentioned fine powder, mixing, drying, be ground into fine powder, the direct compression of full-powder or the back tabletting of granulating add appropriate amount of auxiliary materials etc. and make, and it is characterized in that:
1. gynecological inflammation resisting dispersion tablet is that five kinds of Chinese medicine such as part Radix Sophorae Flavescentis, Cortex Phellodendri, Semen Phaseoli, Fructus Forsythiae and Herba Leonuri are decocted with water secondary, 2 hours for the first time, 1 hour for the second time, collecting decoction, filter, filtrate is concentrated into the thick paste that relative density is 1.31～1.35 (60～80 ℃).The doubly amount that adds water is 4-12 times.
2. gynecological inflammation resisting dispersion tablet is with dried cream powder and right amount of auxiliary materials mixing, the direct compression or the back tabletting of granulating.
3. added adjuvant is in the following adjuvant one or more in the technology: microcrystalline Cellulose, low-substituted hydroxypropyl cellulose, carboxymethyl starch sodium, polyvinylpolypyrrolidone, cross-linking sodium carboxymethyl cellulose, Pulvis Talci, starch, magnesium stearate etc.
4. added supplementary product consumption is in the technology: 5-50% microcrystalline Cellulose, 3-30% low-substituted hydroxypropyl cellulose, 3-30% carboxymethyl starch sodium, 3-30% polyvinylpolypyrrolidone, 3-30% cross-linking sodium carboxymethyl cellulose, Pulvis Talci, starch, magnesium stearate etc. are an amount of.
Formula constituent of the present invention is: Radix Sophorae Flavescentis 250g, Herba Polygoni cymosi 250g, Cortex Phellodendri 150g, Fructus Forsythiae 50g, Herba Leonuri 30g, Semen Phaseoli 30g, Folium Artemisiae Argyi 30g, Radix Angelicae Sinensis 30g, Radix Linderae 30g.
More than nine the flavor, get Radix Sophorae Flavescentis 160g, Cortex Phellodendri 90g, Semen Phaseoli 15g, Fructus Forsythiae 15g, be ground into fine powder, sieve, standby.The five tastes such as residue Radix Sophorae Flavescentis, Cortex Phellodendri, Semen Phaseoli, Fructus Forsythiae and Herba Leonuri decoct with water secondary, 2 hours for the first time, 1 hour for the second time, collecting decoction filters, and filtrate is concentrated into the thick paste that relative density is 1.31～1.35 (60～80 ℃), add above-mentioned fine powder and right amount of auxiliary materials, mixing, drying is ground into fine powder, tabletting, promptly.
In gynecological inflammation resisting dispersion tablet agent and the preparation method, quantitatively Radix Sophorae Flavescentis, Cortex Phellodendri, Semen Phaseoli, that Fructus Forsythiae powder is broken into fine powder is standby; Quantitatively Radix Sophorae Flavescentis, Cortex Phellodendri, Semen Phaseoli, Fructus Forsythiae and Herba Leonuri, the above five tastes, decocting boil that to be concentrated into thick paste standby; Then with above-mentioned standby material, make dispersible tablet and finish a whole set of manufacture method by national standard prescription the requirements adding appropriate amount of auxiliary materials that feeds intake.This medicine is dosage form technological innovation on existing capsular basis, and agent changes into takes more conveniently, and the dispersible tablet that onset is more fast is benefited the common people.This medical instrument has blood circulation promoting and blood stasis dispelling, the effect of heat clearing and damp drying, and clinical damp heat downward flowing type pelvic inflammatory disease, vaginitis, the chronic cervicitis of being used for the treatment of, disease is seen diseases such as leucorrhea with red and white discharge, pudendal pruritus, hemorrhage, dysmenorrhea.Dispersible tablet is met water disintegrate fast, and is more easy for patients to accept and be ready to take.And carry, easy to use, be clinical welcome and safe, stable, effective medicine, be the ideal product of modern pharmaceutical enterprise.
Embodiment:
Gynecological inflammation resisting dispersion tablet of the present invention and preparation method is characterized in that:
Gynecological inflammation resisting dispersion tablet method for making, the main component of gynecological inflammation resisting dispersion tablet is by Radix Sophorae Flavescentis, Herba Polygoni cymosi, Cortex Phellodendri, Fructus Forsythiae, Herba Leonuri, Semen Phaseoli, Folium Artemisiae Argyi, Radix Angelicae Sinensis, the Radix Linderae.More than nine the flavor, get part Radix Sophorae Flavescentis, Cortex Phellodendri, Semen Phaseoli, Fructus Forsythiae, be ground into fine powder, sieve, standby.The five tastes such as residue decoct with water secondary, 2 hours for the first time, 1 hour for the second time, collecting decoction filtered, filtrate is concentrated into the thick paste that relative density is 1.31～1.35 (60～80 ℃), add above-mentioned fine powder, mixing, drying, be ground into fine powder, the direct compression of full-powder or the back tabletting of granulating add appropriate amount of auxiliary materials etc. and make, and it is characterized in that:
1, the scorching dispersible tablet of woman is that five kinds of Chinese medicine such as part Radix Sophorae Flavescentis, Cortex Phellodendri, Semen Phaseoli, Fructus Forsythiae and Herba Leonuri are decocted with water secondary, and 2 hours for the first time, 1 hour for the second time, collecting decoction filtered, and filtrate is concentrated into the thick paste that relative density is 1.31～1.35 (60～80 ℃).The doubly amount that adds water is 4-12 times.
2, gynecological inflammation resisting dispersion tablet is with dried cream powder and right amount of auxiliary materials mixing, the direct compression or the back tabletting of granulating.
3, added adjuvant is in the following adjuvant one or more in the technology: microcrystalline Cellulose, low-substituted hydroxypropyl cellulose, carboxymethyl starch sodium, polyvinylpolypyrrolidone, cross-linking sodium carboxymethyl cellulose, Pulvis Talci, starch, magnesium stearate etc.
4, added supplementary product consumption is in the technology: 5-50% microcrystalline Cellulose, 3-30% low-substituted hydroxypropyl cellulose, 3-30% carboxymethyl starch sodium, 3-30% polyvinylpolypyrrolidone, 3-30% cross-linking sodium carboxymethyl cellulose, Pulvis Talci, starch, magnesium stearate etc. are an amount of.
Formula constituent of the present invention is: Radix Sophorae Flavescentis 250g, Herba Polygoni cymosi 250g, Cortex Phellodendri 150g, Fructus Forsythiae 50g, Herba Leonuri 30g, Semen Phaseoli 30g, Folium Artemisiae Argyi 30g, Radix Angelicae Sinensis 30g, Radix Linderae 30g.
More than nine the flavor, get Radix Sophorae Flavescentis 160g, Cortex Phellodendri 90g, Semen Phaseoli 15g, Fructus Forsythiae 15g, be ground into fine powder, sieve, standby.The five tastes such as residue Radix Sophorae Flavescentis, Cortex Phellodendri, Semen Phaseoli, Fructus Forsythiae and Herba Leonuri decoct with water secondary, 2 hours for the first time, 1 hour for the second time, collecting decoction filters, and filtrate is concentrated into the thick paste that relative density is 1.31～1.35 (60～80 ℃), add above-mentioned fine powder and right amount of auxiliary materials, mixing, drying is ground into fine powder, tabletting, promptly.
In gynecological inflammation resisting dispersion tablet agent and the preparation method, quantitatively Radix Sophorae Flavescentis, Cortex Phellodendri, Semen Phaseoli, that Fructus Forsythiae powder is broken into fine powder is standby; Quantitatively Radix Sophorae Flavescentis, Cortex Phellodendri, Semen Phaseoli, Fructus Forsythiae and Herba Leonuri, the above five tastes, decocting boil that to be concentrated into thick paste standby; Then with above-mentioned standby material, make dispersible tablet and finish a whole set of manufacture method by national standard prescription the requirements adding appropriate amount of auxiliary materials that feeds intake.This medicine is dosage form technological innovation on existing capsular basis, and agent changes into takes more conveniently, and the dispersible tablet that onset is more fast is benefited the common people.This medical instrument has blood circulation promoting and blood stasis dispelling, the effect of heat clearing and damp drying, and clinical damp heat downward flowing type pelvic inflammatory disease, vaginitis, the chronic cervicitis of being used for the treatment of, disease is seen diseases such as leucorrhea with red and white discharge, pudendal pruritus, hemorrhage, dysmenorrhea.Dispersible tablet is met water disintegrate fast, and is more easy for patients to accept and be ready to take.And carry, easy to use, be clinical welcome and safe, stable, effective medicine, be the ideal product of modern pharmaceutical enterprise.
Claims (7)
1, a kind of gynecological inflammation resisting dispersion tablet and preparation method is characterized in that: formula constituent of the present invention is:
Radix Sophorae Flavescentis 250g, Herba Polygoni cymosi 250g, Cortex Phellodendri 150g, Fructus Forsythiae 50g, Herba Leonuri 30g, Semen Phaseoli 30g, Folium Artemisiae Argyi 30g, Radix Angelicae Sinensis 30g, Radix Linderae 30g.
2, gynecological inflammation resisting dispersion tablet according to claim 1 and preparation method, its manufacture method is characterised in that: gets Radix Sophorae Flavescentis 160g, Cortex Phellodendri 90g, Semen Phaseoli 15g, Fructus Forsythiae 15g, is ground into fine powder, sieve, standby.The five tastes such as residue Radix Sophorae Flavescentis, Cortex Phellodendri, Semen Phaseoli, Fructus Forsythiae and Herba Leonuri decoct with water secondary, 2 hours for the first time, 1 hour for the second time, collecting decoction filters, and filtrate is concentrated into the thick paste that relative density is 1.31～1.35 (60～80 ℃), add above-mentioned fine powder and right amount of auxiliary materials, mixing, drying is ground into fine powder, tabletting, promptly.
3, gynecological inflammation resisting dispersion tablet according to claim 1 and preparation method, its manufacture method is characterised in that: gynecological inflammation resisting dispersion tablet method for making, the main component of gynecological inflammation resisting dispersion tablet is by Radix Sophorae Flavescentis, Herba Polygoni cymosi, Cortex Phellodendri, Fructus Forsythiae, Herba Leonuri, Semen Phaseoli, Folium Artemisiae Argyi, Radix Angelicae Sinensis, the Radix Linderae.More than nine the flavor, get part Radix Sophorae Flavescentis, Cortex Phellodendri, Semen Phaseoli, Fructus Forsythiae, be ground into fine powder, sieve, standby.The five tastes such as residue decoct with water secondary, 2 hours for the first time, 1 hour for the second time, collecting decoction filters, and filtrate is concentrated into the thick paste that relative density is 1.31～1.35 (60～80 ℃), add above-mentioned fine powder, mixing, drying is ground into fine powder, the direct compression of full-powder or the back tabletting of granulating add appropriate amount of auxiliary materials etc. and make.
4, gynecological inflammation resisting dispersion tablet according to claim 1 and preparation method, its manufacture method is characterised in that: gynecological inflammation resisting dispersion tablet is that five kinds of Chinese medicine such as part Radix Sophorae Flavescentis, Cortex Phellodendri, Semen Phaseoli, Fructus Forsythiae and Herba Leonuri are decocted with water secondary, 2 hours for the first time, 1 hour for the second time, collecting decoction, filter, filtrate is concentrated into the thick paste that relative density is 1.31～1.35 (60～80 ℃).The doubly amount that adds water is 4-12 times.
5, gynecological inflammation resisting dispersion tablet according to claim 1 and preparation method, its manufacture method is characterised in that: gynecological inflammation resisting dispersion tablet is with dried cream powder and right amount of auxiliary materials mixing, the direct compression or the back tabletting of granulating.
6, gynecological inflammation resisting dispersion tablet according to claim 1 and preparation method, its manufacture method is characterised in that: added adjuvant is one or more in the following adjuvant in the technology: microcrystalline Cellulose, low-substituted hydroxypropyl cellulose, carboxymethyl starch sodium, polyvinylpolypyrrolidone, cross-linking sodium carboxymethyl cellulose, Pulvis Talci, starch, magnesium stearate etc.
7, gynecological inflammation resisting dispersion tablet according to claim 1 and preparation method, its manufacture method is characterised in that: added supplementary product consumption is in the technology: 5-50% microcrystalline Cellulose, 3-30% low-substituted hydroxypropyl cellulose, 3-30% carboxymethyl starch sodium, 3-30% polyvinylpolypyrrolidone, 3-30% cross-linking sodium carboxymethyl cellulose, Pulvis Talci, starch, magnesium stearate etc. are an amount of.
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| CN 200610032657 CN1839981A (en) | 2006-01-05 | 2006-01-05 | Gynecological inflammation resisting dispersion tablet and its preparation method |
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| CN 200610032657 CN1839981A (en) | 2006-01-05 | 2006-01-05 | Gynecological inflammation resisting dispersion tablet and its preparation method |
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Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101966300A (en) * | 2010-07-12 | 2011-02-09 | 泰一和浦（北京）中医药研究院有限公司 | Chinese medicinal composition for treating leucorrhoea hemorrhage and preparation method thereof |
| CN102028794A (en) * | 2010-12-01 | 2011-04-27 | 贵州远程制药有限责任公司 | Gynecological disease resisting gel for treating gynecological disease and preparation method thereof |
| EP2343065A1 (en) * | 2008-09-11 | 2011-07-13 | Qingdao Qiyuan Bio-technologies Co., Ltd. | The pharmaceutical composition containing ferulic acid and matrine compounds, the preparation and the use thereof |
| CN102526342A (en) * | 2012-02-02 | 2012-07-04 | 李坤 | Traditional Chinese medicine preparation for treating chronic cervicitis |
| CN103800860A (en) * | 2012-11-14 | 2014-05-21 | 董根荣 | Medicine for treating wind-cold type common cold and preparation method thereof |
-
2006
- 2006-01-05 CN CN 200610032657 patent/CN1839981A/en active Pending
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2343065A1 (en) * | 2008-09-11 | 2011-07-13 | Qingdao Qiyuan Bio-technologies Co., Ltd. | The pharmaceutical composition containing ferulic acid and matrine compounds, the preparation and the use thereof |
| EP2343065A4 (en) * | 2008-09-11 | 2012-09-19 | Qingdao Qiyuan Bio Technologies Co Ltd | The pharmaceutical composition containing ferulic acid and matrine compounds, the preparation and the use thereof |
| CN101966300A (en) * | 2010-07-12 | 2011-02-09 | 泰一和浦（北京）中医药研究院有限公司 | Chinese medicinal composition for treating leucorrhoea hemorrhage and preparation method thereof |
| CN101966300B (en) * | 2010-07-12 | 2011-12-28 | 泰一和浦（北京）中医药研究院有限公司 | Chinese medicinal composition for treating leucorrhoea hemorrhage and preparation method thereof |
| CN102028794A (en) * | 2010-12-01 | 2011-04-27 | 贵州远程制药有限责任公司 | Gynecological disease resisting gel for treating gynecological disease and preparation method thereof |
| CN102526342A (en) * | 2012-02-02 | 2012-07-04 | 李坤 | Traditional Chinese medicine preparation for treating chronic cervicitis |
| CN103800860A (en) * | 2012-11-14 | 2014-05-21 | 董根荣 | Medicine for treating wind-cold type common cold and preparation method thereof |
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