CN1403103A - Arthralgia pain treating bolus and its prepn - Google Patents
Arthralgia pain treating bolus and its prepn Download PDFInfo
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- Medicines Containing Plant Substances (AREA)
Abstract
The arthralgia pain treating bolus of the present invention is one kind of plant medicine for treating rheumatism. The medicine has high curative effect, less toxic side effect and low cost. The medicine is prepared with pubescent angelica root, parasitic loranthus, largeleaf gentian root, ledebouriella root, asarum herb and other 19 kinds of Chinese medicinal materials and through grinding, mixing, stoving and other steps. It has the functions of invigorating vital energy and blood, nourishing liver and kidney, expelling wind and wetness, tranquilizing and stopping pain. It is used in treating arthralgia, liver and kidney deficiency and other diseases.
Description
Technical field belongs to the rheumatismal medicine preparation technique of the treatment that is made of vegetable material field.
Background technology applicant thinks that rheumatism or rheumatoid also are commonly encountered diseases, frequently-occurring disease, and at present roughly the same medicine is quite a lot on the drug market, but these medicine partial heats or cold partially, toxic and side effects greatly, medicine strength is single.In order to verify the application's novelty, the applicant had once carried out the Searches of Patent Literature, a piece of writing surplus the associated documents of tentatively finding existing ten, as " the rheumatoid medicine of a kind of treatment " (application number: 96122290), " rheumatism capsule " (application number: 98111602), " the arthritic specific drug of a kind of treatment rheumatic and rheumatoid " (application number: 97104088), " plaster for treating arthralgia-syndrome " (application number: 96121445), " liniment Tongbining for cold-type arthralgia " (application number: 97107971) or the like, the applicant thinks that these treat rheumatism, though rheumatoid medicine is being consistent with the application's case aspect therapeutic purposes and the curative effect, but prescription and preparation method are inequality, and mostly be unguentum or wash liniment in these disclosed medicines, these are to constitute the foundation that the application has the patent probability.Before this, the applicant once proposed the patent application of " rheumatism treating nux vomica medicine powder ", (application number: 01114363.0, the applying date: 2001.7.19), but this case and the former are fully inequality at aspects such as component, production technology, dosage forms.In addition, also carry out market survey, found no identical therewith medicine public offering, also do not obtained the disclosed information of identical pharmaceutical formulation and technology of preparing.
Summary of the invention technical problem to be solved by this invention is, be the rheumatisant, comprise rheumatism cold (muscle) arthralgia, diseases such as rheumatic arthritis, rheumatoid arthritis and ankylosing spondylitis provide a kind of and can overcome property of medicine partial heat or cold partially, medicine strength is single, toxic and side effects is bigger, the medicine of the defective that can not take into account, it should have curative effect preferably, and is easy to use, be easy to carry about with one, toxic and side effects is little, price is low.This is a starting point of developing arthralgia pain treating bolus.
For this reason, the technical solution adopted in the present invention is as follows:
Arthralgia pain treating bolus is made up of the plant material of following weight ratio: Radix Angelicae Pubescentis 20 weight portions, parasitic 14 weight portions, Radix Gentianae Macrophyllae 14 weight portions, Radix Saposhnikoviae 14 weight portions, Herba Asari 14 weight portions, Rhizoma Chuanxiong 14 weight portions, Radix Angelicae Sinensis 14 weight portions, the Radix Rehmanniae 8 weight portions, Radix Rehmanniae Preparata 8 weight portions, Radix Paeoniae Rubra 8 weight portions, the Radix Paeoniae Alba 8 weight portions, Ramulus Cinnamomi 12 weight portions, Poria 14 weight portions, Cortex Eucommiae (processed with salt) 14 weight portions, Radix Cyathulae (processed with wine) 14 weight portions, Radix Codonopsis 14 weight portions, Radix Glycyrrhizae Preparata 14 weight portions, six dawn 14 weight portions, the Radix Astragali 14 weight portions, Caulis Spatholobi 14 weight portions, Radix Salviae Miltiorrhizae 14 weight portions, the Rhizoma Atractylodis Macrocephalae 14 weight portions, Cortex Phellodendri 14 weight portions, Cortex Cinnamomi 3 weight portions.
Arthralgia pain treating bolus is prepared according to following technological process:
(1) raw material gives processing, screen fresh, do not have go mouldy, the plant material of free from insect pests, the weight ratio of getting each raw material composition is: Radix Angelicae Pubescentis 20 weight portions, parasitism, Radix Gentianae Macrophyllae, Radix Saposhnikoviae, Herba Asari, Rhizoma Chuanxiong, Radix Angelicae Sinensis, Poria, processed with salt Cortex Eucommiae, processed with wine Radix Cyathulae, Radix Codonopsis, Radix Glycyrrhizae Preparata, six dawn, the Radix Astragali, Caulis Spatholobi, Radix Salviae Miltiorrhizae, the Rhizoma Atractylodis Macrocephalae, each 14 weight portion of Cortex Phellodendri, Ramulus Cinnamomi 12 weight portions, the Radix Rehmanniae, Radix Rehmanniae Preparata, Radix Paeoniae Rubra, each 8 weight portion of the Radix Paeoniae Alba, Cortex Cinnamomi 3 weight portions;
(2) the processed with salt Cortex Eucommiae is made, with Cortex Eucommiae remove residual, stay rough bark, clean shredding, be 100: 2 by its ratio with salt, salt is soluble in water, and salt is 1: 5 with the ratio of water, mixes thoroughly, run through, place again in the pot and fry to old brown, when silk is easily broken with oil-sand, take out, cool, shakeout is pulverized, sieve through 80 orders, standby;
(3) Radix Glycyrrhizae (processed with honey), selecting the Radix Glycyrrhizae tabellae and the ratio of refined honey for use is 100: 25, and refined honey is diluted with certain amount of boiling water, adds Radix Glycyrrhizae tabellae again and mixes thoroughly, and moistening places in the pot again and fries to tack-free being advisable of surperficial pale brown color with slow fire, and taking-up cools, and pulverizes, and sieves through 80 orders, and is standby;
(4) processed with wine Radix Cyathulae is got Radix Cyathulae and removes reed head, impurity, cleans, and runs through, and is cut into oblique sheet, and it is placed yellow wine, and ratio between two is 100: 10, mixes thoroughly, and moistening is saturating, place again pot with slow fire fry in, taking-up cools, and pulverizes, sieves through 80 orders, and is standby;
(5) Radix Angelicae Pubescentis, parasitism, Radix Gentianae Macrophyllae, Radix Saposhnikoviae, Herba Asari, Rhizoma Chuanxiong, Radix Angelicae Sinensis, Poria, Radix Codonopsis, six dawn, the Radix Astragali, Caulis Spatholobi, Radix Salviae Miltiorrhizae, the Rhizoma Atractylodis Macrocephalae, Cortex Phellodendri, Ramulus Cinnamomi, the Radix Rehmanniae, Radix Rehmanniae Preparata, Radix Paeoniae Rubra, the Radix Paeoniae Alba and Cortex Cinnamomi powder system, can concoct respectively with reference to the standard of one one of country's " pharmacopeia " (version in 2000), promptly pulverize, sieve with 80 orders, be powdery, divide and deposit, standby;
(6) take by weighing every flavor raw material with the equivalent incremental method, mixing again, sieve the mixing fine powders shape;
(7) wet-pill making is used purified water, even deionized water, or distilled water mixes well mutually with mixing fine powders shape raw material, and the ratio of the two is 1: 2, it is inserted in the coating pan again, presses the wet-milling modulus method of having granulated, and makes it constantly to increase to be shaped, and makes wet ball by 6 of every grams;
(8) oven dry, the wet ball of the screening of learning from else's experience places the heated air circulation type baking oven, and the stand is even, dries under 58 ℃ condition, and constantly stirs, and takes out after oven dry in 6～8 hours;
(9) quality inspection packing, every bottle 120 gram.
Pharmacological evaluation proves: the Radix Astragali, Rhizoma Atractylodis Macrocephalae QI invigorating are set upright in this pill prescription, invigorating the spleen to clear away damp pathogen is monarch, Radix Angelicae Pubescentis, the wind-cold damp pathogen between volt wind and the part of the body cavity below the umbilicus, housing the bladder, kidneys and bowels and muscles and bones of dispelling, Radix Saposhnikoviae, tea Macrophylla expelling wind and dampness Shujin, Herba Asari disperses yin channel wind and cold and rheumatism of muscles and bones and pain relieving is a minister, parasitism, Radix Cyathulae, Cortex Eucommiae, the liver and kidney tonifying wind-damp dispelling of holding concurrently, Radix Angelicae Sinensis, Rhizoma Chuanxiong, Radix Paeoniae, Radix Rehmanniae are nourished blood and blood, Radix Salviae Miltiorrhizae, the current blood vessels of Caulis Spatholobi are assistant, and the Radix Glycyrrhizae coordinating the actions of various ingredients in a prescription is for making.
In order to ensure the quality of this product, the inventor had once carried out microscopical identification.Get this product, put microscopically and observe: needle-like calcium oxalate crystal is tiny, long 10-32um, be gathered in brokenly in the parenchyma cell, contain inulin in the parenchyma cell, the surface shows to put to thank shape texture, fiber bunchy or loose has longitudinal crack from, wall thickness, surface, the two ends normal off is cleaved into the palpus shape, or more truncate; The parenchyma cell similar round includes the similar round nucleus, contains prism of calcium oxalate in the parenchyma cell, forms crystalline cellulose, parietal cell similar round or spindle, and what have is branch-like, wall thickness, laminated striation is obvious; Rubber thread slivering or twist agglomeratingly, the surface is graininess.
In preparation, should follow the standard of an appendix IA of Pharmacopoeia of the People's Republic of China version in 2000 defined.
This product is the tan watered pill, feeble QI, the flavor little sweet.
Function with cure mainly: compensate qi and blood, nourishing the liver and kidney, expelling wind and dampness, mind tranquilizing and the heart calming, migratory arthralgia pain relieving.Arthromyodynia with the passing of time, caused by liver and kidney deficiency, the lumbago and skelalgia of insufficiency of vital energy and blood, the soft unable myopathy of flaccidity, diseases such as podomere joint stuffiness, apathy, fear of cold aversion to wind, shortness of breath and palpitation.
Usage and consumption: the secondary of swallowing every day, each 6 grams or follow the doctor's advice, but sugaring sooner or later or Mel warm boiled water.
Attention: avoid cold and uncooked food.
Specification: 120g/ bottle.
Storage: airtight, protection against the tide.
In order to verify curative effect of the present invention, the applicant carries out clinical trial in three batches to 360 routine patients, now its result is summarized as follows:
First test is treatment rheumatic arthritis patient 120 examples, belong to traditional Chinese medical science arthromyodynia category, its disease divides the generic Liver and kidney empty type, and promptly the patient can not support essence because of deficiency of the liver, and suffering from a deficiency of the kidney can not main bone, the hepatic and renal function degradation, insufficiency of vital energy and blood, meridians lose supports, and the damp of having a cold again invasion and attack cause meridians, numbness resistance in muscles and bones joint is obstructed and show the arthralgia of slower development, swelling, stiff, deformity and dysfunction, the touching difficulty of the course of disease more is main clinical manifestation, alternative matched group 88 examples, and two groups of courses of disease reach 20 years most, the shortest 4 months, take medicine every day three times, the morning, noon and afternoon each once, dosage 4-10g/ time, decide on state of an illness weight, have no adverse reaction after taking medicine.This test is decided to be three courses of treatment, and be 20 days each course of treatment, criterion of therapeutical effect: clinical cure, transference cure, movable function recover normal.Produce effects is that arthralgia is clearly better, and it is normal that functional activity recovers substantially.Effectively for arthralgia alleviates, range of activity increases.Invalid do not have change for the joint symptom of getting involved, by above-mentioned standard rating, clinical cure 40 examples in 120 examples account for 33.33% as a result after three courses of treatment, produce effects 68 examples account for 56.66%, effective 12 examples account for 10%, and total effective rate 100%, matched group are taken NSAID (non-steroidal anti-inflammatory drug), indometacin, dosage is 2mg/kg/d every day 2 times, effective 70 examples of 88 examples account for 79.43%, total effective rate 79.43% as a result.
Second batch of test is treatment ankylosing spondylitis 120 examples, patient's polyphyly and heredoimmunity infect, environmental factorss etc. are relevant, belong to rheumatism involving the bone category in the traditional Chinese medical science arthromyodynia, the traditional Chinese medical science thinks that the polyphyly kidney-jing deficiency is few, be difficult the skeleton of supplementing nutrition, waist is shown by the yang-energy weakened defensive QI of suffering from a deficiency of the kidney simultaneously, the wind-cold damp pathogen institute that takes advantage of a weak point, arm, hip pain and inconvenient activity, waist deadlock etc. is a main clinic symptoms, decide patient 120 example and be the treatment group, alternative 90 examples be matched group, and the patient does not wait to rigid spine or the lopsided fixedly state of an illness weight of hunchback so that the dorsal column movable function is limited, comprise early, in, three phases of evening, two groups of courses of disease the longest are 10 years, and the shortest is 3 months, and the treatment group is taken medicine three times every day, early, in, evening respectively once, dosage 4-10g/ time is decided on state of an illness weight, has no adverse reaction after taking medicine.This test was a course of treatment in fixed 20 days, treated three courses of treatment.The scorching anti-inflammatory drug indometacin of matched group 90 example clothes non-steroidals 2mg/kg/d divides the secondary administration, and treatment group effective percentage is 90% after three courses of treatment, and the matched group effective percentage is 44.44%.
The 3rd batch of test is treatment myasthenia patient 120 examples, belongs to the sick category of traditional Chinese medical science flaccidity, and its card belongs to the caused by liver and kidney deficiency type, relax and do not receive with brothers' weakness, muscle arteries and veins, amyotrophy is a main clinical manifestation, decides patient's 120 examples and is the treatment group, alternative 68 examples are matched group, two groups of courses of disease are the longest to be 12 years, the shortlyest is 3 months, the oldest 82 years old, minimum 54 years old, muscular strength is 0-II, and muscular tension has weakening in various degree, simultaneously with in various degree amyotrophy.The treatment group is obeyed arthralgia pain treating bolus three times every day, early, middle and late each once, taking medicine after meal, dosage 4-10g/ time is decided on state of an illness weight, has no adverse reaction after taking medicine.This test was a course of treatment in fixed 30 days, treat three courses of treatment, and matched group 68 example usefulness western medicines are after three courses of treatment, and treatment group effective percentage is 93.33%, and the matched group effective percentage is 58.82%.
The applicant thinks: the beneficial effect that contrasts existing similar medicine arthralgia pain treating bolus is:
(1) have compensate qi and blood, nourishing the liver and kidney, expelling wind and dampness, the migratory arthralgia pain relieving improves the human body immunity, treating both the principal and secondary aspects of a disease.
(2) preparation method is simple, and medicine is easy to apolegamy.
(3) course of treatment is shorter, evident in efficacy.
(4) easy to use, mouthfeel is good, has no side effect and untoward reaction.
Description of drawings is according to technique scheme, and preparation technology's flow process of arthralgia pain treating bolus as shown in drawings.Now each link restock among this figure is described as follows:
(1) raw material gives processing, screen fresh, do not have go mouldy, the plant material of free from insect pests, take by weighing its weight portion by the weight ratio of each component.
(2) the processed with salt Cortex Eucommiae is made, and removes that it is residual, stay rough bark, clean shredding, and it is 100: 2 with the ratio of salt; Salt is 1: 5 with the ratio of water, and salt is soluble in water, and itself and the Cortex Eucommiae are mixed thoroughly, runs through; Place again in the pot and fry to old brown with oil-sand, when silk evening is disconnected, taking-up; Cool shakeout; Pulverize, sieve, standby.
(3) Radix Glycyrrhizae (processed with honey), Radix Glycyrrhizae tabellae is 100: 25 with the ratio of refined honey, and refined honey is diluted with certain amount of boiling water; The adding Radix Glycyrrhizae tabellae is mixed thoroughly with it, moistening; Place again in the pot and fry to tack-free being advisable of surperficial pale brown color with slow fire; Taking-up cools, pulverizes, 80 orders sieve, and are standby.
(4) processed with wine Radix Cyathulae removes raw material reed head, impurity, cleans, runs through, cuts into slices; Place that yellow wine is mixed thoroughly, moistening is to saturating, Radix Cyathulae is 100: 10 with the ratio of yellow wine; Place in the pot fry with slow fire do, cool, pulverize, 80 orders sieve, and are standby.
(5) the powder system of 21 flavor vegetable materials such as Radix Angelicae Pubescentis is all concocted with reference to the standard of one one of national " pharmacopeia " (200 years version), and pulverize separately sieves through 80 orders, is powdery, and branch is deposited, and is standby.
(6) take by weighing every flavor vegetable material with the equivalent incremental method, mixing sieves again.
(7) wet-pill making is used purified water, and promptly deionized water or distilled water are mixed well mutually with mixing fine powders shape raw material, and the ratio of the two is it to be inserted in coating pan at 1: 2 again, presses the wet-milling modulus method of having granulated, and makes it constantly to increase to be shaped, and makes wet ball by 6 of every grams.
(8) oven dry, the wet ball of the screening of learning from else's experience places the heated air circulation type baking oven, and the stand is even, dries under 58 ℃ condition, and constantly stirs, and takes out after oven dry in 6～8 hours.
(9) quality inspection packing, every bottle 120 gram, i.e. making finishes.
The specific embodiment: the applicant think above-mentioned each given material component, weight portion when the technological process of production be and realize a kind of typical module of the present invention.
Claims (2)
1. arthralgia pain treating bolus is characterized in that being made up of the plant material of following weight ratio:
Parasitic 14 weight portions of Radix Angelicae Pubescentis 20 weight portions
Radix Gentianae Macrophyllae 14 weight portion Radix Saposhnikoviaes 14 weight portions
Herba Asari 14 weight portion Rhizoma Chuanxiongs 14 weight portions
The Radix Angelicae Sinensis 14 weight portion Radix Rehmanniae 8 weight portions
Radix Rehmanniae Preparata 8 weight portion Radix Paeoniae Rubra 8 weight portions
The Radix Paeoniae Alba 8 weight portion Ramulus Cinnamomi 12 weight portions
Poria 14 weight portion Cortex Eucommiaes (processed with salt) 14 weight portions
Radix Cyathulae (processed with wine) 14 weight portion Radix Codonopsis 14 weight portions
Radix Glycyrrhizae Preparata 14 weight portions six dawn 14 weight portion
The Radix Astragali 14 weight portion Caulis Spatholobis 14 weight portions
The Radix Salviae Miltiorrhizae 14 weight portion Rhizoma Atractylodis Macrocephalaes 14 weight portions
Cortex Phellodendri 14 weight portion Cortex Cinnamomis 3 weight portions
2. the preparation method of an arthralgia pain treating bolus is characterized in that being prepared according to following technological process:
(1) raw material gives processing, screen fresh, do not have go mouldy, the plant material of free from insect pests, the weight ratio of getting each raw material composition is: Radix Angelicae Pubescentis 20 weight portions, parasitism, Radix Gentianae Macrophyllae, Radix Saposhnikoviae, Herba Asari, Rhizoma Chuanxiong, Radix Angelicae Sinensis, Poria, processed with salt Cortex Eucommiae, processed with wine Radix Cyathulae, Radix Codonopsis, Radix Glycyrrhizae Preparata, six dawn, the Radix Astragali, Caulis Spatholobi, Radix Salviae Miltiorrhizae, the Rhizoma Atractylodis Macrocephalae, each 14 weight portion of Cortex Phellodendri, Ramulus Cinnamomi 12 weight portions, the Radix Rehmanniae, Radix Rehmanniae Preparata, Radix Paeoniae Rubra, each 8 weight portion of the Radix Paeoniae Alba, Cortex Cinnamomi 3 weight portions;
(2) the processed with salt Cortex Eucommiae is made, with Cortex Eucommiae remove residual, stay rough bark, clean shredding, be 100: 2 by its ratio with salt, salt is soluble in water, and salt is 1: 5 with the ratio of water, mixes thoroughly, runs through; Place again in the pot and fry to old brown, when silk is easily broken, take out, cool with oil-sand; Shakeout is pulverized, and sieves through 80 orders, and is standby;
(3) Radix Glycyrrhizae (processed with honey), selecting the Radix Glycyrrhizae tabellae and the ratio of refined honey for use is 100: 25, and refined honey is diluted with certain amount of boiling water, adds Radix Glycyrrhizae tabellae again and mixes thoroughly, and moistening places in the pot again and fries to tack-free being advisable of surperficial pale brown color with slow fire, and taking-up cools, and pulverizes, and sieves through 80 orders, and is standby;
(4) processed with wine Radix Cyathulae is got Radix Cyathulae and removes reed head, impurity, cleans, and runs through, and is cut into oblique sheet, and it is placed yellow wine, and ratio between two is 100: 10, mixes thoroughly, and moistening is saturating; Place pot to fry with slow fire again and do, taking-up cools; Pulverize, sieve through 80 orders, standby;
(5) Radix Angelicae Pubescentis, parasitism, Radix Gentianae Macrophyllae, Radix Saposhnikoviae, Herba Asari, Rhizoma Chuanxiong, Radix Angelicae Sinensis, Poria, Radix Codonopsis, six dawn, the Radix Astragali, Caulis Spatholobi, Radix Salviae Miltiorrhizae, the Rhizoma Atractylodis Macrocephalae, Cortex Phellodendri, Ramulus Cinnamomi, the Radix Rehmanniae, Radix Rehmanniae Preparata, Radix Paeoniae Rubra, the Radix Paeoniae Alba and Cortex Cinnamomi powder system, can concoct respectively with reference to the standard of one one of country's " pharmacopeia " (version in 2000), promptly pulverize, sieve with 80 orders, be powdery, divide and deposit, standby;
(6) take by weighing every flavor raw material with the equivalent incremental method, through the mixing that sieves, after the sieve the mixing fine powders shape;
(7) wet-pill making is used purified water, even deionized water, or distilled water mixes well mutually with mixing fine powders shape raw material, and the ratio of the two is 1: 2; Again it is inserted in the coating pan, press the wet-milling modulus method of having granulated, make it constantly to increase to be shaped, make wet ball by 6 of every grams;
(8) oven dry, the wet ball of the screening of learning from else's experience places the heated air circulation type baking oven, and the stand is even, dries under 58 ℃ condition, and constantly stirs, and takes out after oven dry in 6～8 hours;
(9) quality inspection packing, every bottle 120 gram.
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| CN 01128388 CN1289114C (en) | 2001-08-30 | 2001-08-30 | Arthralgia pain treating bolus and its prepn |
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| CN 01128388 CN1289114C (en) | 2001-08-30 | 2001-08-30 | Arthralgia pain treating bolus and its prepn |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102406752A (en) * | 2011-11-25 | 2012-04-11 | 荣成市交通诊所 | Chinese medicinal composition for treating arthralgia |
| CN102716262A (en) * | 2012-06-29 | 2012-10-10 | 隋孝忠 | Traditional Chinese medicine formula for curing ankylosing spondylitis |
| CN102861307A (en) * | 2012-09-06 | 2013-01-09 | 李承平 | Group of wild ginger pain-relieving combined tablets |
| CN103735725A (en) * | 2014-01-27 | 2014-04-23 | 山东新希望六和集团有限公司 | Medicament for treating pig rheumatism and preparation method thereof |
| CN103933353A (en) * | 2014-04-24 | 2014-07-23 | 周云飞 | Medicament for treating rheumatism and gout |
| CN105168445A (en) * | 2015-10-12 | 2015-12-23 | 新乡医学院 | Traditional Chinese medicine composition for treating rheumatic arthritis |
| CN105250887A (en) * | 2015-11-27 | 2016-01-20 | 刘艳丽 | Traditional Chinese medicine electuary for treatment and nursing of ICU myasthenia gravis and preparation method |
| CN105878689A (en) * | 2016-06-02 | 2016-08-24 | 迟涛胜 | Traditional Chinese medicine for treating ankylosing spondylitis |
| CN107137556A (en) * | 2016-03-01 | 2017-09-08 | 梁冬喜 | Stupid numbness 'Tongluowan ' |
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| CN100520931C (en) * | 2005-10-25 | 2009-07-29 | 普诚科技股份有限公司 | Method for starting data phase-locked loop when track following and correlation device |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102406752A (en) * | 2011-11-25 | 2012-04-11 | 荣成市交通诊所 | Chinese medicinal composition for treating arthralgia |
| CN102716262A (en) * | 2012-06-29 | 2012-10-10 | 隋孝忠 | Traditional Chinese medicine formula for curing ankylosing spondylitis |
| CN102861307A (en) * | 2012-09-06 | 2013-01-09 | 李承平 | Group of wild ginger pain-relieving combined tablets |
| CN103735725A (en) * | 2014-01-27 | 2014-04-23 | 山东新希望六和集团有限公司 | Medicament for treating pig rheumatism and preparation method thereof |
| CN103735725B (en) * | 2014-01-27 | 2016-09-21 | 山东新希望六和集团有限公司 | For treating rheumatismal medicine of pig and preparation method thereof |
| CN103933353A (en) * | 2014-04-24 | 2014-07-23 | 周云飞 | Medicament for treating rheumatism and gout |
| CN103933353B (en) * | 2014-04-24 | 2016-05-04 | 周云飞 | A kind of medicine for the treatment of rheumatism, gout |
| CN105168445A (en) * | 2015-10-12 | 2015-12-23 | 新乡医学院 | Traditional Chinese medicine composition for treating rheumatic arthritis |
| CN105250887A (en) * | 2015-11-27 | 2016-01-20 | 刘艳丽 | Traditional Chinese medicine electuary for treatment and nursing of ICU myasthenia gravis and preparation method |
| CN107137556A (en) * | 2016-03-01 | 2017-09-08 | 梁冬喜 | Stupid numbness 'Tongluowan ' |
| CN105878689A (en) * | 2016-06-02 | 2016-08-24 | 迟涛胜 | Traditional Chinese medicine for treating ankylosing spondylitis |
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| CN1289114C (en) | 2006-12-13 |
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Effective date of registration: 20180808 Address after: 437201 Xianning Matang Rheumatism Hospital, Xianning, Hubei 2 Patentee after: Xianning Matang Rheumatism Hospital Limited Address before: 437021 rheumatology specialist hospital, 5 Zeng Pu street, Ma Tang, Xianning, Hubei Patentee before: Zhen Shuiqing |
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