CN1239179C - Chinese medicine for treating diabetes and preparation method therefor - Google Patents
Chinese medicine for treating diabetes and preparation method therefor Download PDFInfo
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- CN1239179C CN1239179C CNB031582613A CN03158261A CN1239179C CN 1239179 C CN1239179 C CN 1239179C CN B031582613 A CNB031582613 A CN B031582613A CN 03158261 A CN03158261 A CN 03158261A CN 1239179 C CN1239179 C CN 1239179C
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Abstract
The present invention discloses a Chinese patent medicine for treating diabetes, which is prepared from raw materials such as ant, dragonfly, snakegourd root, milkvetch root, evonymus alata, faenum graecum, ginseng and rehmannia root according to a certain weight proportion. The present invention can be prepared into any general oral preparations. The Chinese patent medicine of the present invention has the advantages of exact compatibility, regulation of immunity of organism, kidney nourishment, yin nourishment, heat clearing, fluid production, moderate moistening tonification and high cure rate.
Description
Technical field
The present invention relates to a kind of Chinese patent medicine, especially for the Chinese patent medicine of treatment diabetes.
Background technology
Diabetes are to be difficult to one of frequently-occurring disease of curing clinically, and its clinical treatment method adopts insulin injection mostly or takes the Drug therapy blood sugar control and the urine sugar level of blood sugar lowering and so on; In case the drug withdrawal state of an illness can recur again, cure rate is lower, and some patient medication beyond the region of objective existence of taking off mourning clothes also will be kept on a diet.
Summary of the invention
Purpose of the present invention is the shortcoming and deficiency in order to overcome above-mentioned prior art existence just, and a kind of Chinese medicine ingredients that adopts fully is provided, and more effectively treats the Chinese patent medicine of diabetes,
Another object of the present invention has provided the preparation method of this Chinese medicinal capsule dosage form.
The object of the present invention is achieved like this: diabetes are the scope of " diabetes " in motherland's medical science, think that its morbidity is dirty for " lung ", " stomach ", " kidney " three.Main pathogenesis be that " kidney " deficiency of YIN is scorching with " lung " " stomach ", thus the pathological change emphasis of the deficiency of YIN at kidney, scorching pathological change emphasis is at lung, stomach.Deficiency of the kidney yin and lung stomach can influence each other, and deficiency of kidney yin can cause lung dryness of the stomach heat and consume body fluid; Otherwise lung dryness of the stomach heat increases the weight of deficiency of kidney yin again; With the passing of time the course of disease then can cause kidney insufficiency, symptom such as polydipsia, polyuria, polyphagia occur, become thin.
This medicament selection Formica fusca, Aeschna melanictera, Radix Trichosanthis, the Radix Astragali, Ramulus Euonymi, Semen Trigonellae, Radix Ginseng, the Radix Rehmanniae are raw material, these medicines are made up make each efficacy of drugs produce synergism, thereby can effectively treat diabetes.Wherein Formica fusca is a monarch drug, nourishing the liver and kidney and adjusting immunity; The Aeschna melanictera nature and flavor are sweet, but the adjusting of body autoimmunity is strengthened in the tonifying YANG of kidney tonifying reinforcing YIN-essence, has the effect of moisturizing simultaneously, and Radix Trichosanthis attaches to the lung and stomach meridians, the clearing away lung-heat and moistening for dryness of quenching one's thirst, and both are ministerial drug; The Radix Astragali, Radix Ginseng play promote the production of body fluid and heat-removing, ascending YANG and invigorating QI, and Ramulus Euonymi leads to stasis of blood removing blood stasis, and the Semen Trigonellae the kidney warming is by wet, and Radix Rehmanniae nourishing kidney clearing stomach makes for assistant altogether.
Each crude drug consumption of medicine of the present invention also carries out a large amount of clinically groping constantly to improve to sum up to draw through the inventor, and various crude drug consumptions all have better curative effect in the scope of following weight ratio:
Formica fusca 15-45%
Aeschna melanictera 15-25%
Radix Trichosanthis 10-15%
Radix Astragali 5-10%
Ramulus Euonymi 5-10%
Semen Trigonellae 5-10%
Radix Ginseng 5-10%
Radix Rehmanniae 5-10%
The preferred weight proportioning of said medicine is:
Formica fusca 40%
Aeschna melanictera 20%
Radix Trichosanthis 15%
The Radix Astragali 5%
Ramulus Euonymi 5%
Semen Trigonellae 5%
Radix Ginseng 5%
The Radix Rehmanniae 5%
Formica fusca of the present invention is a Polyhachis vicina Roger.
Chinese medicine of the present invention can adopt the conventional method of Chinese medicine preparation to be prepared into any conventional oral preparations.Most preferred scheme is that Formica fusca, Aeschna melanictera, Radix Trichosanthis are ground into powder, and with other crude drug decocting together, condensed water decocting liquid is then pulverized powder and concentrated decocting mixing after drying and made capsule.But these do not limit protection scope of the present invention.
Preferably, the preparation method of medicine of the present invention is as follows:
(1) in proportion weighting raw materials Formica fusca, Radix Trichosanthis, Radix Ginseng and its pulverize separately become in powder, it is standby to cross 70 mesh sieves:
(2) Aeschna melanictera, the Radix Astragali, Ramulus Euonymi, Semen Trigonellae, the Radix Rehmanniae five kinds of Chinese medicine with described weight proportion decocts with water twice, and each decocting time 2 hours filters to get filtrate, and merges filtrate twice;
(3) filtrate of step (2) gained being concentrated into relative density is 1.28 concentrated solution;
(4) with the middle powder mix homogeneously of step (3) gained concentrated solution and step (1);
(5) ℃ following drying in temperature≤80;
(6) dried medicine is ground into fine powder, has just made the active constituent of medicine of the present invention.
(7) with 70% alcohol granulation, with granule incapsulate capsule formulation;
Described (2) twice decocting time of boiling of step are 2 hours.
Required various conventional adjuvant when utilizing the active component of above-mentioned preparation method gained can also add the various different dosage form of preparation is prepared into any peroral dosage form commonly used with the method for Chinese medicinal of routine, as pill, powder, tablet etc.
Good effect of the present invention is: this medicine has regulates immunity of organism, nourishing kidney-YIN, clearing away heat and promoting production of body fluid, not only mends but also clear, benefit is and oiliness, and advantage clearly and only is the good medicine of treatment diabetes.
The specific embodiment
Below in conjunction with embodiment the present invention is described in further detail.
Embodiment 1
(1) with Formica fusca 240 gram, Aeschna melanictera 120 grams, Radix Trichosanthis 90 grams, respectively wear in powder to cross 70 mesh sieves standby;
(2) yellow late-maturing 30 grams, Ramulus Euonymi 30 grams, Semen Trigonellae 30 grams, Radix Ginseng 30 grams, the Radix Rehmanniae 30 grams are decocted with water 2 times, each decocting time 2 hours merges filtrate twice;
(3) filtrate of step (2) gained is concentrated into density 1.28 concentrated solution:
(4) with the middle powder mix homogeneously of step (3) gained concentrated solution and step (1);
(5) ℃ following drying in temperature≤80;
(6), wear into fine powder then and cross 100 mesh sieves and make with three kinds of mix homogeneously after drying of step (1);
(7) with 70% alcohol granulation, with granule make 1000 capsules specifications, 0.38 gram/
GrainCapsule.
Embodiment 2
(1) with Formica fusca 90 gram, Aeschna melanictera 120 grams, Radix Trichosanthis 90 grams, respectively wear in powder to cross 70 mesh sieves standby;
(2) Radix Astragali 60 grams, Ramulus Euonymi 60 grams, Semen Trigonellae 60 grams, Radix Ginseng 60 grams, the Radix Rehmanniae 60 grams are decocted with water 2 times, each decocting time 2 hours merges filtrate twice;
(3) filtrate of step (2) gained is concentrated into density 1.28 concentrated solution;
(4) with the middle powder mix homogeneously of step (3) gained concentrated solution and step (1);
(5) ℃ following drying in temperature≤80;
(6), wear into fine powder then and cross 100 mesh sieves and make with three kinds of mix homogeneously after drying of step (1):
(7) with 70% alcohol granulation, with granule make 1000 capsules specifications, 0.38 gram/
GrainCapsule.
Embodiment 3
(1) with Formica fusca 270 gram, Aeschna melanictera 95 grams, Radix Trichosanthis 110 grams, respectively wear in powder to cross 70 mesh sieves standby;
(2) yellow late-maturing 25 grams, Ramulus Euonymi 25 grams, Semen Trigonellae 25 grams, Radix Ginseng 25 grams, the Radix Rehmanniae 25 grams are decocted with water 2 times, each decocting time 2 hours merges filtrate twice;
(3) filtrate of step (2) gained is concentrated into density 1.28 concentrated solution;
(4) with the middle powder mix homogeneously of step (3) gained concentrated solution and step (1);
(5) ℃ following drying in temperature≤80;
(6), wear into fine powder then and cross 100 mesh sieves and make with three kinds of mix homogeneously after drying of step (1);
(7) with 70% alcohol granulation, with granule make 1000 capsules specifications, 0.38 gram/
GrainCapsule.Clinical efficacy:
Accept example surplus the patient 400 altogether for medical treatment.
Non-insulin-dependent diabetes mellitus (type ii diabetes), disease is seen: polyorexia, polyuria, the body volume etc. of becoming thin, breathe hard; Simultaneously insulin dependent diabetes mellitus (IDDM) (type i diabetes) also there is the auxiliary treatment effect.
(1) Therapeutic Method
Each 5, every day 2-3 time, serious symptom person doubles to take taking medicine after meal.3 months is a course of treatment, general 1 course of treatment.
(2) curative effect determinate standard
1, clinical cure: treat 1 course of treatment, clinical symptoms, sign disappear, and blood sugar detection is reduced to 3.9-6.1mmol/L, urinary glucose determination ():
2, take a turn for the better: treat 1 course of treatment, clinical symptoms, sign disappear substantially, and blood sugar detection is between 6.1-10mmol/L, and urinary glucose determination is below (++):
3, invalid: as not reach improvement standard person.
(3) therapeutic effect
Treat 400 examples, clinical cure 320 examples account for 80%; 75 examples that take a turn for the better account for 19%; Invalid 5 examples account for 1%, total effective rate 98%.
(4) model case
Open * *, man 54 years old, cadre, people from Maanshan City, Anhui Province.Be diagnosed as non-insulin-dependent diabetes mellitus through local hospital in 1996, and took the Western medicine blood sugar lowering for a long time, xerostomia, bitter taste, thirsty polydipsia, accompany weak, soreness of the waist and knees, tinnitus, the heating of brothers' heart, binocular blurred vision, skin pruritus, red tongue with thin fur, thready and rapid pulse, fasting glucose 12.6mmol/L, glucose in urine (++ ++) ketoboidies (-), doctor trained in Western medicine: type ii diabetes, the traditional Chinese medical science: diabetes, deficiency of both QI and YIN.Give clothes XUANJU glycosuria Yiganning capsule, each 5, every day 3 times, warm water delivery service, after taking traditional Chinese medicine 10 days, xerostomia is thirsty to be subtracted greatly, the sugared 9.8mmol/L that has a blood test after January, glucose in urine (+++) continue to take medicine, former blood sugar lowering thing slowly successively decreases.After March, transference cure, chemical examination blood glucose, glucose in urine is all normal, clinical cure.
Claims (4)
1, a kind of Chinese medicine for the treatment of diabetes is characterized in that it is made by the following raw materials by weight percent medicine:
Formica fusca 15-45%
Aeschna melanictera 15-25%
Radix Trichosanthis 10-15%
Radix Astragali 5-10%
Ramulus Euonymi 5-10%
Semen Trigonellae 5-10%
Radix Ginseng 5-10%
Radix Rehmanniae 5-10%.
2, the Chinese medicine of treatment diabetes according to claim 1 is characterized in that the consumption of above-mentioned raw materials medicine is: Formica fusca 40%, Aeschna melanictera 20%, Radix Trichosanthis 15%, the Radix Astragali 5%, Ramulus Euonymi 5%, Semen Trigonellae 5%, Radix Ginseng 5% and the Radix Rehmanniae 5%.
3, a kind of claim 1 or 2 described preparation method of Chinese medicine is characterized in that it comprises the following steps:
(1) weighting raw materials Formica fusca, Radix Trichosanthis, Radix Ginseng in proportion, and powder during its pulverize separately become, it is standby to cross 70 mesh sieves;
(2) Aeschna melanictera, the Radix Astragali, Ramulus Euonymi, Semen Trigonellae, the Radix Rehmanniae five kinds of Chinese medicine with described weight proportion decocts with water twice, and each decocting time 2 hours filters to get filtrate, and merges filtrate twice;
(3) filtrate of step (2) gained being concentrated into relative density is 1.28 concentrated solution;
(4) with the middle powder mix homogeneously of step (3) gained concentrated solution and step (1);
(5) ℃ following drying in temperature≤80;
(6) dried medicine is ground into fine powder, has just made the active constituent of medicine of the present invention.
(7) with 70% alcohol granulation, granule is incapsulated, capsule formulation;
4, preparation method according to claim 3 is characterized in that (2) twice decocting time of boiling of step are 2 hours.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB031582613A CN1239179C (en) | 2003-09-16 | 2003-09-16 | Chinese medicine for treating diabetes and preparation method therefor |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB031582613A CN1239179C (en) | 2003-09-16 | 2003-09-16 | Chinese medicine for treating diabetes and preparation method therefor |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1524570A CN1524570A (en) | 2004-09-01 |
| CN1239179C true CN1239179C (en) | 2006-02-01 |
Family
ID=34287203
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNB031582613A Expired - Fee Related CN1239179C (en) | 2003-09-16 | 2003-09-16 | Chinese medicine for treating diabetes and preparation method therefor |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1239179C (en) |
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2003
- 2003-09-16 CN CNB031582613A patent/CN1239179C/en not_active Expired - Fee Related
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| Publication number | Publication date |
|---|---|
| CN1524570A (en) | 2004-09-01 |
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