CN112178974A - Refrigerator suitable for full-automatic biological medicine production based on semiconductor refrigeration piece - Google Patents
Refrigerator suitable for full-automatic biological medicine production based on semiconductor refrigeration piece Download PDFInfo
- Publication number
- CN112178974A CN112178974A CN202010925645.1A CN202010925645A CN112178974A CN 112178974 A CN112178974 A CN 112178974A CN 202010925645 A CN202010925645 A CN 202010925645A CN 112178974 A CN112178974 A CN 112178974A
- Authority
- CN
- China
- Prior art keywords
- refrigerator
- low
- cooling water
- microorganism
- heat
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000004065 semiconductor Substances 0.000 title claims abstract description 48
- 238000005057 refrigeration Methods 0.000 title claims abstract description 29
- 238000004519 manufacturing process Methods 0.000 title claims abstract description 18
- 239000003814 drug Substances 0.000 title claims abstract description 9
- 244000005700 microbiome Species 0.000 claims abstract description 70
- 239000000498 cooling water Substances 0.000 claims abstract description 51
- 238000001816 cooling Methods 0.000 claims abstract description 22
- 239000012774 insulation material Substances 0.000 claims abstract description 13
- 238000007789 sealing Methods 0.000 claims abstract description 12
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 11
- 238000010257 thawing Methods 0.000 claims abstract description 9
- 239000011810 insulating material Substances 0.000 claims description 12
- 238000004321 preservation Methods 0.000 claims description 12
- 239000000110 cooling liquid Substances 0.000 claims description 9
- 229960000074 biopharmaceutical Drugs 0.000 claims description 8
- 238000003384 imaging method Methods 0.000 claims description 7
- 238000009413 insulation Methods 0.000 claims description 7
- 239000000463 material Substances 0.000 claims description 6
- 230000017525 heat dissipation Effects 0.000 claims description 4
- 239000000126 substance Substances 0.000 claims description 4
- 230000007306 turnover Effects 0.000 claims description 3
- 230000005494 condensation Effects 0.000 abstract description 3
- 238000009833 condensation Methods 0.000 abstract description 3
- 230000010354 integration Effects 0.000 abstract description 3
- 230000001954 sterilising effect Effects 0.000 abstract description 3
- 238000004659 sterilization and disinfection Methods 0.000 abstract description 3
- 230000009286 beneficial effect Effects 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 230000008569 process Effects 0.000 description 2
- 238000013473 artificial intelligence Methods 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 230000002708 enhancing effect Effects 0.000 description 1
- 239000004519 grease Substances 0.000 description 1
- 230000000813 microbial effect Effects 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 229920001296 polysiloxane Polymers 0.000 description 1
Images
Classifications
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F25—REFRIGERATION OR COOLING; COMBINED HEATING AND REFRIGERATION SYSTEMS; HEAT PUMP SYSTEMS; MANUFACTURE OR STORAGE OF ICE; LIQUEFACTION SOLIDIFICATION OF GASES
- F25D—REFRIGERATORS; COLD ROOMS; ICE-BOXES; COOLING OR FREEZING APPARATUS NOT OTHERWISE PROVIDED FOR
- F25D11/00—Self-contained movable devices, e.g. domestic refrigerators
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
- F16J—PISTONS; CYLINDERS; SEALINGS
- F16J15/00—Sealings
- F16J15/02—Sealings between relatively-stationary surfaces
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F25—REFRIGERATION OR COOLING; COMBINED HEATING AND REFRIGERATION SYSTEMS; HEAT PUMP SYSTEMS; MANUFACTURE OR STORAGE OF ICE; LIQUEFACTION SOLIDIFICATION OF GASES
- F25B—REFRIGERATION MACHINES, PLANTS OR SYSTEMS; COMBINED HEATING AND REFRIGERATION SYSTEMS; HEAT PUMP SYSTEMS
- F25B21/00—Machines, plants or systems, using electric or magnetic effects
- F25B21/02—Machines, plants or systems, using electric or magnetic effects using Peltier effect; using Nernst-Ettinghausen effect
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F25—REFRIGERATION OR COOLING; COMBINED HEATING AND REFRIGERATION SYSTEMS; HEAT PUMP SYSTEMS; MANUFACTURE OR STORAGE OF ICE; LIQUEFACTION SOLIDIFICATION OF GASES
- F25D—REFRIGERATORS; COLD ROOMS; ICE-BOXES; COOLING OR FREEZING APPARATUS NOT OTHERWISE PROVIDED FOR
- F25D17/00—Arrangements for circulating cooling fluids; Arrangements for circulating gas, e.g. air, within refrigerated spaces
- F25D17/04—Arrangements for circulating cooling fluids; Arrangements for circulating gas, e.g. air, within refrigerated spaces for circulating air, e.g. by convection
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F25—REFRIGERATION OR COOLING; COMBINED HEATING AND REFRIGERATION SYSTEMS; HEAT PUMP SYSTEMS; MANUFACTURE OR STORAGE OF ICE; LIQUEFACTION SOLIDIFICATION OF GASES
- F25D—REFRIGERATORS; COLD ROOMS; ICE-BOXES; COOLING OR FREEZING APPARATUS NOT OTHERWISE PROVIDED FOR
- F25D19/00—Arrangement or mounting of refrigeration units with respect to devices or objects to be refrigerated, e.g. infrared detectors
- F25D19/003—Arrangement or mounting of refrigeration units with respect to devices or objects to be refrigerated, e.g. infrared detectors with respect to movable containers
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F25—REFRIGERATION OR COOLING; COMBINED HEATING AND REFRIGERATION SYSTEMS; HEAT PUMP SYSTEMS; MANUFACTURE OR STORAGE OF ICE; LIQUEFACTION SOLIDIFICATION OF GASES
- F25D—REFRIGERATORS; COLD ROOMS; ICE-BOXES; COOLING OR FREEZING APPARATUS NOT OTHERWISE PROVIDED FOR
- F25D21/00—Defrosting; Preventing frosting; Removing condensed or defrost water
- F25D21/06—Removing frost
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F25—REFRIGERATION OR COOLING; COMBINED HEATING AND REFRIGERATION SYSTEMS; HEAT PUMP SYSTEMS; MANUFACTURE OR STORAGE OF ICE; LIQUEFACTION SOLIDIFICATION OF GASES
- F25D—REFRIGERATORS; COLD ROOMS; ICE-BOXES; COOLING OR FREEZING APPARATUS NOT OTHERWISE PROVIDED FOR
- F25D21/00—Defrosting; Preventing frosting; Removing condensed or defrost water
- F25D21/14—Collecting or removing condensed and defrost water; Drip trays
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F25—REFRIGERATION OR COOLING; COMBINED HEATING AND REFRIGERATION SYSTEMS; HEAT PUMP SYSTEMS; MANUFACTURE OR STORAGE OF ICE; LIQUEFACTION SOLIDIFICATION OF GASES
- F25D—REFRIGERATORS; COLD ROOMS; ICE-BOXES; COOLING OR FREEZING APPARATUS NOT OTHERWISE PROVIDED FOR
- F25D23/00—General constructional features
- F25D23/02—Doors; Covers
- F25D23/028—Details
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F25—REFRIGERATION OR COOLING; COMBINED HEATING AND REFRIGERATION SYSTEMS; HEAT PUMP SYSTEMS; MANUFACTURE OR STORAGE OF ICE; LIQUEFACTION SOLIDIFICATION OF GASES
- F25D—REFRIGERATORS; COLD ROOMS; ICE-BOXES; COOLING OR FREEZING APPARATUS NOT OTHERWISE PROVIDED FOR
- F25D25/00—Charging, supporting, and discharging the articles to be cooled
- F25D25/02—Charging, supporting, and discharging the articles to be cooled by shelves
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F25—REFRIGERATION OR COOLING; COMBINED HEATING AND REFRIGERATION SYSTEMS; HEAT PUMP SYSTEMS; MANUFACTURE OR STORAGE OF ICE; LIQUEFACTION SOLIDIFICATION OF GASES
- F25D—REFRIGERATORS; COLD ROOMS; ICE-BOXES; COOLING OR FREEZING APPARATUS NOT OTHERWISE PROVIDED FOR
- F25D29/00—Arrangement or mounting of control or safety devices
- F25D29/003—Arrangement or mounting of control or safety devices for movable devices
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F25—REFRIGERATION OR COOLING; COMBINED HEATING AND REFRIGERATION SYSTEMS; HEAT PUMP SYSTEMS; MANUFACTURE OR STORAGE OF ICE; LIQUEFACTION SOLIDIFICATION OF GASES
- F25D—REFRIGERATORS; COLD ROOMS; ICE-BOXES; COOLING OR FREEZING APPARATUS NOT OTHERWISE PROVIDED FOR
- F25D29/00—Arrangement or mounting of control or safety devices
- F25D29/005—Mounting of control devices
Landscapes
- Engineering & Computer Science (AREA)
- General Engineering & Computer Science (AREA)
- Mechanical Engineering (AREA)
- Physics & Mathematics (AREA)
- Thermal Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Combustion & Propulsion (AREA)
- Devices That Are Associated With Refrigeration Equipment (AREA)
Abstract
The invention discloses a refrigerator suitable for full-automatic biological medicine production based on semiconductor refrigeration sheets, wherein a cooling water tank is arranged inside a heat insulation material, a cold and hot surface exchange semiconductor refrigeration sheet is arranged at the top end of the cooling water tank, a microorganism container storage support is arranged at the top end of the cold and hot surface exchange semiconductor refrigeration sheet, a low-temperature cavity is arranged at the top end of the microorganism container storage support, a plurality of microorganism storage containers are supported on the microorganism container storage support, an ice tank cover is arranged at the top end of each microorganism storage container, a motor is arranged on one side of the refrigerator, the motor is connected with the refrigerator cover through a rotating shaft, a radiator is connected to one side of the cooling water tank through a cooling water pipe, and a cooling fan is arranged at. Full-automatic operation, and integration in the full-automatic production process. The defrosting can be automated. The high-performance sealing structure can reduce the condensation of water vapor in air entering the low-temperature cavity as much as possible. The low-temperature cavity can form a completely closed space, and the sterile environment can be kept after sterilization.
Description
Technical Field
The invention relates to a full-automatic refrigerator for biological medicine production, which can fully automatically solve the problems of refrigeration, unfreezing, transportation, operation and the like of microorganisms in the production process, and can fully automatically defrost.
Background
Biopharmaceuticals are in a fast-growing phase, in which certain microorganisms need to be refrigerated at low temperatures and need to be thawed before being put into use formally. Due to the presence of water vapor in the low-temperature refrigeration environment, frost can form in the low-temperature refrigeration space, and storage, transportation and operation of microorganisms are affected. Meanwhile, artificial intelligence is widely applied to the bio-pharmaceuticals, and full automation of refrigeration, unfreezing, transportation, operation and the like of microorganisms in the bio-pharmaceuticals process is expected to be achieved, and manual participation is reduced.
Disclosure of Invention
The invention aims to provide a refrigerator based on a semiconductor refrigeration sheet and suitable for full-automatic biological medicine production, so as to solve the problems in the background technology.
In order to achieve the purpose, the invention provides the following technical scheme: a refrigerator suitable for full-automatic biological medicine production based on a semiconductor refrigerating sheet comprises a motor, a rotating shaft, a refrigerator cover shell, a sealing ring, a microorganism storage container, a low-temperature cavity, a microorganism container storage support, a cold and hot surface exchange semiconductor refrigerating sheet, a cooling water tank, a heat insulating material, a cooling water pipe, a cooling fan and a radiator, wherein the inside of the heat insulating material is provided with the cooling water tank, the top end of the cooling water tank is provided with the cold and hot surface exchange semiconductor refrigerating sheet, the top end of the cold and hot surface exchange semiconductor refrigerating sheet is provided with the microorganism container storage support, the top end of the microorganism container storage support is provided with the low-temperature cavity, the microorganism container storage support is supported with a plurality of microorganism storage containers, the top end of the microorganism storage container is provided with the refrigerator cover, one side of the refrigerator is provided with the motor, and the refrigerator cover are connected through, one side of the cooling water tank is connected with a radiator through a cooling water pipe, and the bottom of the radiator is provided with a cooling fan.
Further, the functions are as follows:
a motor: the motor drives the refrigerator cover to turn over through the rotating shaft, so that the automatic opening and closing of the refrigerator is realized;
rotating shaft: the rotating shaft transmits the power of the motor to the refrigerator cover;
a refrigerator cover: the refrigerator comprises a hard heat-insulating material, a refrigerator cover heat-insulating layer, a refrigerator cover shell and a heat-insulating material, wherein the heat insulation of a low-temperature cavity and the external environment is realized together with the heat-insulating material;
sealing rings: isolating the low temperature chamber from air exchange with the external environment;
a microorganism storage container: microorganisms are stored in a microorganism storage container, the microorganism storage container is provided with characteristics convenient for an imaging system to identify, is placed on a microorganism storage container bracket and is kept at a fixed position, and is convenient for a manipulator to identify and clamp;
a low-temperature cavity: a low temperature chamber of a refrigerator in which microorganisms are refrigerated;
microorganism storage container holder: a rack for holding a microorganism storage container;
cold and hot face exchange semiconductor refrigeration piece: the semiconductor refrigerating sheet can realize the exchange of cold and hot surfaces through the exchange of the anode and the cathode of the power supply;
a cooling water tank: when the cold and hot surfaces exchange the semiconductor refrigerating sheet for refrigeration, the hot surface is tightly attached to the cooling water tank, and the heat of the hot surface is transferred to the cooling water tank and is dissipated through the cooling water pipe, the radiator and the cooling fan;
thermal insulation material: the low-temperature cavity and the refrigerator cover are used for realizing heat insulation between the low-temperature cavity and the external environment;
cooling water pipes: a channel for connecting the cooling water tank and the radiator and circulating the cooling liquid;
a cooling fan: the heat sink is forced to convect, and the heat dissipation is accelerated;
a radiator: the cold and hot surfaces brought by the cooling liquid exchange the heat generated by the semiconductor refrigerating sheet.
Furthermore, the refrigerator cover shell is wrapped on the periphery of the refrigerator cover heat-insulating layer, and the hard heat-insulating material is arranged at the top end of the low-temperature cavity.
Furthermore, a sealing ring is arranged between the low-temperature cavity and the hard heat-insulating material.
Furthermore, the cooling water tank is communicated with the radiator through a cooling water pipe.
Further, the refrigerator has the following characteristics:
the switch of the refrigerator cover is driven by a motor, manual operation is not needed, and the refrigerator cover is suitable for robot operation;
the microorganism storage container is provided with characteristics convenient for the imaging system to identify, is placed on the microorganism storage container bracket and is kept at a fixed position, so that the manipulator can conveniently identify and clamp;
the refrigerator cover and the low-temperature cavity are sealed, so that when the low-temperature cavity is at low temperature during refrigeration of the cold and hot surface exchange semiconductor refrigerating sheet, water vapor in the outside air enters the low-temperature cavity to generate excessive condensed water or frost;
after the anode and the cathode of a power supply of the cold and hot surface exchange semiconductor refrigerating sheet are exchanged, the low-temperature cavity can be heated, so that the unfreezing of substances in the microorganism storage container and the defrosting of the low-temperature cavity are realized;
the low-temperature cavity is in the heat preservation of the hard heat preservation material, the refrigerator cover heat preservation layer and the heat preservation material and is insulated from the outside;
the heat generated by the semiconductor refrigerating sheet is transferred to the radiator through the cooling liquid circulation in the cooling water tank and the cooling water pipe, and the heat is dissipated by forced convection of the cooling fan.
Compared with the prior art, the invention has the beneficial effects that:
1. full-automatic operation, and integration in the full-automatic production process.
2. The defrosting can be automated.
3. The high-performance sealing structure can reduce the condensation of water vapor in air entering the low-temperature cavity as much as possible.
4. The low-temperature cavity can form a completely closed space, and the sterile environment can be kept after sterilization.
Drawings
Fig. 1 is a schematic diagram of a refrigerator based on semiconductor refrigeration sheets and suitable for full-automatic biological medicine production.
The reference numerals are explained below:
in the figure: 1. a motor; 2. a rotating shaft; 3.1, hard heat-insulating materials; 3.2, insulating layer of refrigerator cover; 3.3, refrigerator cover shell; 4. a seal ring; 5. a microorganism storage container; 6. a low temperature chamber; 7. a microbial storage container holder; 8. the cold and hot surfaces exchange semiconductor refrigerating sheets; 9. a cooling water tank; 10. a thermal insulation material; 11. a cooling water pipe; 12. a cooling fan; 13. a heat sink.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all embodiments, and all other embodiments obtained by a person of ordinary skill in the art without creative efforts based on the embodiments of the present invention belong to the protection scope of the present invention.
To facilitate an understanding of the invention, the invention will now be described more fully with reference to the accompanying drawings. Several embodiments of the invention are presented in the drawings. This invention may, however, be embodied in many different forms and should not be construed as limited to the embodiments set forth herein. Rather, these embodiments are provided so that this disclosure will be thorough and complete.
It will be understood that when an element is referred to as being "secured to" another element, it can be directly on the other element or intervening elements may also be present. When an element is referred to as being "connected" to another element, it can be directly connected to the other element or intervening elements may also be present. The terms "vertical," "horizontal," "left," "right," and the like as used herein are for illustrative purposes only.
Unless defined otherwise, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this invention belongs. The terminology used in the description of the invention herein is for the purpose of describing particular embodiments only and is not intended to be limiting of the invention. As used herein, the term "and/or" includes any and all combinations of one or more of the associated listed items.
Referring to fig. 1, the present invention provides a technical solution:
a refrigerator suitable for full-automatic biological medicine production based on semiconductor refrigeration sheets comprises a motor 1, a rotating shaft 2, a refrigerator cover shell 3.3, a sealing ring 4, a microorganism storage container 5, a low-temperature cavity 6, a microorganism container storage support 7, a cold and hot surface exchange semiconductor refrigeration sheet 8, a cooling water tank 9, a heat insulation material 10, a cooling water pipe 11, a cooling fan 12 and a radiator 13, wherein the cooling water tank 9 is arranged inside the heat insulation material 10, the top end of the cooling water tank 9 is provided with the cold and hot surface exchange semiconductor refrigeration sheet 8, the top end of the cold and hot surface exchange semiconductor refrigeration sheet 8 is provided with the microorganism container storage support 7, the top end of the microorganism container storage support 7 is provided with the low-temperature cavity 6, the microorganism container storage support 7 is supported with a plurality of microorganism storage containers 5, and the top end of the microorganism storage container 5 is provided with the refrigerator cover, the refrigerator is characterized in that a motor 1 is arranged on one side of the refrigerator, the motor 1 is connected with a refrigerator cover through a rotating shaft 2, a radiator 13 is connected to one side of a cooling water tank 9 through a cooling water pipe 11, and a cooling fan 12 is arranged at the bottom of the radiator 13.
In an embodiment, please refer to fig. 1, which has the following functions:
a motor 1: the motor 1 drives the refrigerator cover to turn over through the rotating shaft 2, so that the automatic opening and closing of the refrigerator is realized;
a rotating shaft 2: the rotating shaft 2 transmits the power of the motor 1 to the refrigerator cover;
a refrigerator cover: the refrigerator comprises a hard heat-insulation material 3.1, a refrigerator cover heat-insulation layer 3.2, a refrigerator cover shell 3.3 and a heat-insulation material 10, wherein the heat insulation of a low-temperature cavity 6 and the external environment is realized, when a manipulator needs to grab a microorganism storage container in the low- temperature cavity 6 or 5 people need to defrost, a motor 1 works, a refrigerator cover is opened, and after the grabbing or defrosting is finished, the refrigerator cover is closed;
and (4) sealing ring: isolating the low temperature chamber 6 from air exchange with the external environment;
microorganism storage container 5: microorganisms are stored in a microorganism storage container 5, the microorganism storage container 5 is provided with characteristics convenient for an imaging system to identify, is placed on a microorganism storage container bracket 7 and is kept at a fixed position, so that the microorganism storage container is convenient for a manipulator to identify and clamp;
the low-temperature cavity 6: a low temperature chamber 6 of the refrigerator in which microorganisms are refrigerated;
microorganism storage container holder 7: a rack for storing the microorganism storage containers 5;
cold and hot face exchange semiconductor refrigeration sheet 8: the semiconductor refrigerating sheet can realize the exchange of cold and hot surfaces through the exchange of the anode and the cathode of the power supply;
cooling water tank 9: when the cold and hot surface exchange semiconductor refrigerating sheet 8 is used for refrigerating, the hot surface of the semiconductor refrigerating sheet is tightly attached to the cooling water tank 9, and the heat of the hot surface is transferred to the cooling water tank 9 and is dissipated through the cooling water pipe 11, the radiator 13 and the cooling fan 12;
thermal insulation material 10: the low temperature cavity 6 and the external environment are insulated together by the refrigerator cover;
cooling water pipe 11: a passage for connecting the cooling water tank 9 and the radiator 13 and circulating the cooling liquid;
cooling fan 12: the heat radiator 13 is forced to convect to accelerate heat dissipation;
the radiator 13: the cold and hot surfaces brought by the cooling liquid exchange the heat generated by the semiconductor refrigerating sheet 8.
The refrigerator cover shell 3.3 is wrapped on the periphery of the refrigerator cover heat-insulating layer 3.2, and the hard heat-insulating material 3.1 is arranged at the top end of the low-temperature cavity 6.
And a sealing ring 4 is arranged between the low-temperature cavity 6 and the hard heat-insulating material 3.1.
The cooling water tank 9 and the radiator 13 are communicated with each other through a cooling water pipe 11.
Embodiment 2, referring to fig. 1, the refrigerator has the following features:
the switch of the refrigerator cover is driven by the motor 1, manual operation is not needed, and the refrigerator cover is suitable for robot operation;
the microorganism storage container 5 is provided with characteristics convenient for the imaging system to identify, is placed on a bracket of the microorganism storage container 5 and is kept at a fixed position, so that the manipulator can conveniently identify and clamp;
the refrigerator cover and the low-temperature cavity 6 are sealed, so that when the temperature in the low-temperature cavity 6 is low during refrigeration of the cold and hot surface exchange semiconductor refrigerating sheet 8, water vapor in the outside air enters the low-temperature cavity 6 to generate excessive condensed water or frost;
after the power supply anode and the power supply cathode of the cold and hot surface exchange semiconductor refrigerating sheet 8 are exchanged, the low-temperature cavity 6 can be heated, so that the unfreezing of substances in the microorganism storage container 5 and the defrosting of the low-temperature cavity 6 are realized;
the low-temperature cavity 6 is in the heat preservation of the hard heat preservation material 3.1, the refrigerator cover heat preservation layer 3.2 and the heat preservation material 10, and is insulated from the outside;
the heat generated by the cold and hot surface exchanging semiconductor refrigerating sheet 8 during refrigeration is transferred to the radiator 13 through the cooling liquid circulation in the cooling water tank 9 and the cooling water pipe 11, and is dissipated by forced convection by the cooling fan 12.
The form of the process seal ring 6 can be any shape or structure that can achieve a seal.
The refrigerator cover 3 can be in any structure capable of preserving heat.
The cooling fan 12 may not be used.
The features on the microbe storage container 5 that facilitate identification by the imaging system may be in any form.
The microorganism storage container holder 7 may be any structure capable of holding the microorganism storage container 5 in a fixed position, or may be integrated with the low temperature chamber 6.
The space between the cold and hot surface exchange semiconductor refrigerating sheet 8 and the cooling water tank 9 can be filled with heat-conducting silicone grease or other substances for enhancing heat conduction, or not.
The number of the microorganism storage containers 5 stored in the low temperature chamber 6 may be 1 or any other number.
The multiple groups of low-temperature cavities 6 can be used simultaneously, and the multiple groups of low-temperature cavities 6 used simultaneously can be mutually insulated or not insulated.
Compared with the prior art, the invention has the beneficial effects that:
1. full-automatic operation, and integration in the full-automatic production process.
2. The defrosting can be automated.
3. The high-performance sealing structure can reduce the condensation of water vapor in air entering the low-temperature cavity as much as possible.
4. The low-temperature cavity can form a completely closed space, and the sterile environment can be kept after sterilization.
The foregoing illustrates and describes the principles, general features, and advantages of the present invention. It will be understood by those skilled in the art that the present invention is not limited to the embodiments described above, which are described in the specification and illustrated only to illustrate the principle of the present invention, but that various changes and modifications may be made therein without departing from the spirit and scope of the present invention, which fall within the scope of the invention as claimed. The scope of the invention is defined by the appended claims and equivalents thereof.
Claims (6)
1. The utility model provides a be applicable to full-automatic refrigerator for biological medicine production based on semiconductor refrigeration piece, includes motor (1), pivot (2), refrigerator lid shell (3.3), sealing washer (4), microorganism storage container (5), low temperature chamber (6), microorganism container storage support (7), cold and hot face exchange semiconductor refrigeration piece (8), cooling trough (9), insulation material (10), cooling water pipe (11), cooling fan (12) and radiator (13), its characterized in that: the inside of insulation material (10) is equipped with cooling trough (9), the top of cooling trough (9) is equipped with cold and hot face exchange semiconductor refrigeration piece (8), the top of cold and hot face exchange semiconductor refrigeration piece (8) is equipped with the microorganism container and stores support (7), the top that the support (7) was stored to the microorganism container is equipped with low temperature chamber (6), it has a plurality of microorganism storage container (5) to support on support (7) to store the microorganism container, the top of microorganism storage container (5) is equipped with the refrigerator lid, one side of refrigerator is equipped with motor (1), be connected through pivot (2) between motor (1) and the refrigerator lid, one side of cooling trough (9) is connected with radiator (13) through cooling water pipe (11), the bottom of radiator (13) is equipped with cooling fan (12).
2. The refrigerator based on semiconductor chilling plates and suitable for full-automatic biopharmaceutical production of claim, wherein the functions of the refrigerator are as follows:
electric machine (1): the motor (1) drives the refrigerator cover to turn over through the rotating shaft (2), so that the automatic opening and closing of the refrigerator is realized;
a rotating shaft (2): the rotating shaft (2) transmits the power of the motor (1) to the refrigerator cover;
a refrigerator cover: the refrigerator comprises a hard heat-insulation material (3.1), a refrigerator cover heat-insulation layer (3.2), a refrigerator cover shell (3.3) and a heat-insulation material (10) which are used for realizing heat insulation of a low-temperature cavity (6) and the external environment, when a manipulator needs to grab a microorganism storage container in the low-temperature cavity (6) or defrost a person (5), a motor (1) works, a refrigerator cover is opened, and after grabbing or defrosting is finished, the refrigerator cover is closed;
sealing ring (4): separating the low-temperature cavity (6) from air exchange with the external environment;
microorganism storage container (5): microorganisms are stored in a microorganism storage container (5), and the microorganism storage container (5) is provided with characteristics convenient for an imaging system to identify, is placed on a microorganism storage container bracket (7), is kept at a fixed position and is convenient for a manipulator to identify and clamp;
low temperature chamber (6): a low temperature chamber (6) chamber of the refrigerator in which microorganisms are refrigerated;
microorganism storage container holder (7): a rack for storing the microorganism storage container (5);
cold and hot face exchange semiconductor refrigeration piece (8): the semiconductor refrigerating sheet can realize the exchange of cold and hot surfaces through the exchange of the anode and the cathode of the power supply;
cooling water tank (9): when the cold and hot surface exchange semiconductor refrigerating sheet (8) refrigerates, the hot surface is tightly attached to the cooling water tank (9), and the heat of the hot surface is transferred to the cooling water tank (9) and is dissipated through the cooling water pipe (11), the radiator (13) and the cooling fan (12);
thermal insulation material (10): the low-temperature cavity (6) and the refrigerator cover are used for realizing heat insulation between the low-temperature cavity and the external environment;
cooling water pipe (11): a channel for connecting the cooling water tank (9) and the radiator (13) and circulating the cooling liquid;
cooling fan (12): the heat radiator (13) is forced to convect to accelerate heat dissipation;
heat sink (13): the cold and hot surfaces brought by the cooling liquid exchange the heat generated by the semiconductor refrigerating sheet (8).
3. The refrigerator applicable to full-automatic biopharmaceutical production based on semiconductor chilling plates of claim, wherein: the refrigerator cover shell (3.3) is wrapped on the periphery of the refrigerator cover heat-insulating layer (3.2), and the hard heat-insulating material (3.1) is arranged at the top end of the low-temperature cavity (6).
4. The refrigerator applicable to full-automatic biopharmaceutical production based on semiconductor chilling plates of claim, wherein: and a sealing ring (4) is arranged between the low-temperature cavity (6) and the hard heat-insulating material (3.1).
5. The refrigerator applicable to full-automatic biopharmaceutical production based on semiconductor chilling plates of claim, wherein: the cooling water tank (9) is communicated with the radiator (13) through a cooling water pipe (11).
6. The refrigerator applicable to full-automatic biopharmaceutical production based on semiconductor chilling plates of claim, wherein the refrigerator has the following characteristics:
the switch of the refrigerator cover is driven by the motor (1), manual operation is not needed, and the refrigerator cover is suitable for robot operation;
the microorganism storage container (5) is provided with characteristics convenient for an imaging system to identify, is placed on a bracket of the microorganism storage container (5), and is kept at a fixed position so as to be convenient for a manipulator to identify and clamp;
the refrigerator cover and the low-temperature cavity (6) are sealed, so that when the temperature in the low-temperature cavity (6) is low during refrigeration of the cold and hot surface exchange semiconductor refrigeration sheet (8), water vapor in the outside air enters the low-temperature cavity (6) to generate excessive condensed water or frost;
after the positive and negative poles of the power supply of the cold and hot surface exchange semiconductor refrigerating sheet (8) are exchanged, the low-temperature cavity (6) can be heated, so that the thawing of substances in the microorganism storage container (5) and the defrosting of the low-temperature cavity (6) are realized;
the low-temperature cavity (6) is positioned in the heat preservation of the hard heat preservation material (3.1), the refrigerator cover heat preservation layer (3.2) and the heat preservation material (10) and is insulated from the outside;
the heat generated by the cold and hot surface exchanging semiconductor refrigerating sheet (8) during refrigeration is transferred to the radiator (13) through the circulation of cooling liquid in the cooling water tank (9) and the cooling water pipe (11), and forced convection heat dissipation is carried out by the cooling fan (12).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202010925645.1A CN112178974A (en) | 2020-09-07 | 2020-09-07 | Refrigerator suitable for full-automatic biological medicine production based on semiconductor refrigeration piece |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202010925645.1A CN112178974A (en) | 2020-09-07 | 2020-09-07 | Refrigerator suitable for full-automatic biological medicine production based on semiconductor refrigeration piece |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN112178974A true CN112178974A (en) | 2021-01-05 |
Family
ID=73925088
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202010925645.1A Pending CN112178974A (en) | 2020-09-07 | 2020-09-07 | Refrigerator suitable for full-automatic biological medicine production based on semiconductor refrigeration piece |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN112178974A (en) |
Citations (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH1068568A (en) * | 1996-08-27 | 1998-03-10 | Matsushita Electric Works Ltd | Electronic refrigerator |
| CN104697267A (en) * | 2015-03-26 | 2015-06-10 | 哈尔滨商业大学 | Water-cooled dual-refrigeration type semiconductor cold accumulation insulation box |
| CN104909058A (en) * | 2015-05-01 | 2015-09-16 | 大连华工创新科技股份有限公司 | Portable small or minitype constant-temperature box or refrigerator |
| CN205580059U (en) * | 2016-03-18 | 2016-09-14 | 西华大学 | Energy -saving on -vehicle mini -bar |
| CN108592476A (en) * | 2018-05-11 | 2018-09-28 | 南京工业大学 | Semiconductor refrigeration storage box comprising cold-end automatic defrosting device |
| CN208998402U (en) * | 2018-11-07 | 2019-06-18 | 青岛梅莱智能科技有限公司 | A kind of refrigerator of intelligence automatic open close lid |
| CN209165832U (en) * | 2018-11-09 | 2019-07-26 | 格罗贝尔机电(上海)有限公司 | A kind of Portable low-temp injection refrigerator |
| CN210399643U (en) * | 2019-09-19 | 2020-04-24 | 哈尔滨商业大学 | Insulin fridge of water-cooling heat radiation structure |
-
2020
- 2020-09-07 CN CN202010925645.1A patent/CN112178974A/en active Pending
Patent Citations (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH1068568A (en) * | 1996-08-27 | 1998-03-10 | Matsushita Electric Works Ltd | Electronic refrigerator |
| CN104697267A (en) * | 2015-03-26 | 2015-06-10 | 哈尔滨商业大学 | Water-cooled dual-refrigeration type semiconductor cold accumulation insulation box |
| CN104909058A (en) * | 2015-05-01 | 2015-09-16 | 大连华工创新科技股份有限公司 | Portable small or minitype constant-temperature box or refrigerator |
| CN205580059U (en) * | 2016-03-18 | 2016-09-14 | 西华大学 | Energy -saving on -vehicle mini -bar |
| CN108592476A (en) * | 2018-05-11 | 2018-09-28 | 南京工业大学 | Semiconductor refrigeration storage box comprising cold-end automatic defrosting device |
| CN208998402U (en) * | 2018-11-07 | 2019-06-18 | 青岛梅莱智能科技有限公司 | A kind of refrigerator of intelligence automatic open close lid |
| CN209165832U (en) * | 2018-11-09 | 2019-07-26 | 格罗贝尔机电(上海)有限公司 | A kind of Portable low-temp injection refrigerator |
| CN210399643U (en) * | 2019-09-19 | 2020-04-24 | 哈尔滨商业大学 | Insulin fridge of water-cooling heat radiation structure |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US10619916B2 (en) | Devices for use with refrigeration devices including temperature-controlled container systems | |
| KR20030081522A (en) | Use of heat in cold storage appliances | |
| CN214842083U (en) | Vacuum freeze drying equipment | |
| CN112178974A (en) | Refrigerator suitable for full-automatic biological medicine production based on semiconductor refrigeration piece | |
| CN114013827B (en) | Self-maintaining liquid nitrogen type biological preservation container | |
| CN202030171U (en) | Low-temperature turnover box | |
| CN217628422U (en) | Car-T cell culture case of adjustable temperature | |
| CN106766348A (en) | A kind of semiconductor freezer | |
| CN211625803U (en) | Thermal insulation collecting appliance and device | |
| CN215062877U (en) | Freezing and thawing tank for freezing and thawing biological pharmaceutical material | |
| CN210892385U (en) | Semiconductor refrigeration dryer | |
| CN220722086U (en) | Short-time refrigeration preservation box for probiotics | |
| CN213678096U (en) | Portable low-temperature box | |
| CN221586585U (en) | Portable refrigerator | |
| CN216953668U (en) | Freezing and thawing cabinet for freezing and thawing biological pharmaceutical material | |
| CN209355547U (en) | A kind of cold storage plant | |
| CN202598978U (en) | Simple cooling storage device | |
| CN212830342U (en) | Food detection sample save set | |
| CN207894087U (en) | Energy storage device and transport case with it | |
| CN216361461U (en) | Low temperature storage device is used in inactivated vaccine production | |
| CN221893688U (en) | Biological sample storage container of ultralow temperature biological storage device | |
| CN213841468U (en) | A economize on electricity environment-friendly freezer for adhesive raw materials storage | |
| JPH07500484A (en) | Methods and devices for storing foodstuffs, plants, meat and other organic substances | |
| CN216003485U (en) | Portable tissue sample cryopreservation transfer device | |
| JPH0544690Y2 (en) |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20210105 |
|
| RJ01 | Rejection of invention patent application after publication |