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CN111700198A - Composition and beverage for regulating intestines and stomach and promoting appetite and preparation method thereof - Google Patents

Composition and beverage for regulating intestines and stomach and promoting appetite and preparation method thereof Download PDF

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Publication number
CN111700198A
CN111700198A CN202010735201.1A CN202010735201A CN111700198A CN 111700198 A CN111700198 A CN 111700198A CN 202010735201 A CN202010735201 A CN 202010735201A CN 111700198 A CN111700198 A CN 111700198A
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China
Prior art keywords
powder
parts
beverage
hawthorn
malt
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Pending
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CN202010735201.1A
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Chinese (zh)
Inventor
邱成飞
牟书才
吕凤菊
何珊
安珊珊
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Heilongjiang Renhetang Medicine Co ltd
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Heilongjiang Renhetang Medicine Co ltd
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Priority to CN202010735201.1A priority Critical patent/CN111700198A/en
Publication of CN111700198A publication Critical patent/CN111700198A/en
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    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L7/00—Cereal-derived products; Malt products; Preparation or treatment thereof
    • A23L7/20—Malt products
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L13/00—Meat products; Meat meal; Preparation or treatment thereof
    • A23L13/20—Meat products; Meat meal; Preparation or treatment thereof from offal, e.g. rinds, skins, marrow, tripes, feet, ears or snouts
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L19/00—Products from fruits or vegetables; Preparation or treatment thereof
    • A23L19/09—Mashed or comminuted products, e.g. pulp, purée, sauce, or products made therefrom, e.g. snacks
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L19/00—Products from fruits or vegetables; Preparation or treatment thereof
    • A23L19/10—Products from fruits or vegetables; Preparation or treatment thereof of tuberous or like starch containing root crops
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
    • A23L2/38—Other non-alcoholic beverages
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L31/00—Edible extracts or preparations of fungi; Preparation or treatment thereof
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    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/16—Inorganic salts, minerals or trace elements
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56—Materials from animals other than mammals
    • A61K35/57—Birds; Materials from birds, e.g. eggs, feathers, egg white, egg yolk or endothelium corneum gigeriae galli
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06—Fungi, e.g. yeasts
    • A61K36/07—Basidiomycota, e.g. Cryptococcus
    • A61K36/076—Poria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/31—Brassicaceae or Cruciferae (Mustard family), e.g. broccoli, cabbage or kohlrabi
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/734—Crataegus (hawthorn)
    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/75—Rutaceae (Rue family)
    • A61K36/752—Citrus, e.g. lime, orange or lemon
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/894—Dioscoreaceae (Yam family)
    • A61K36/8945—Dioscorea, e.g. yam, Chinese yam or water yam
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    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
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    • A61K36/88—Liliopsida (monocotyledons)
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    • A61K36/8998—Hordeum (barley)
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
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    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs

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Abstract

The invention discloses a composition for regulating intestines and stomach and promoting appetite, a beverage and a preparation method thereof, and relates to the technical field of functional foods. The composite material comprises the following raw materials in parts by weight: 10.8-14.8 parts of malt powder, 8.4-12.4 parts of hawthorn powder, 2.3-6.3 parts of endothelium corneum gigeriae galli powder, 7.3-11.3 parts of orange peel powder, 4.4-8.4 parts of radish seed powder, 1.2-5.2 parts of yam powder, 0.7-1.5 parts of poria cocos powder and 0.1-0.18 part of zinc gluconate. The hawthorn powder, the malt powder, the endothelium corneum gigeriae galli powder, the tangerine peel powder, the radish seed powder, the yam powder and the poria cocos powder are selected as main active substance sources, and the problems of anorexia and picky eating of children are solved in seven aspects of removing indigestion, strengthening the spleen, promoting digestion, stimulating the appetite, eliminating fullness, tonifying qi and promoting qi. The beverage for regulating intestines and stomach and promoting appetite provided by the invention can fundamentally solve the problem of insufficient gastrointestinal motility of children patients.

Description

Composition and beverage for regulating intestines and stomach and promoting appetite and preparation method thereof
Technical Field
The invention relates to the technical field of functional foods, in particular to a composition and a beverage for regulating intestines and stomach and promoting appetite and a preparation method thereof.
Background
The nutrition is the material basis of the growth and development of children, and any food cannot completely meet the requirements of the growth and development of children. The eating behaviors and habits of children not only influence the growth and development of the children, but also are closely related to the health of adults and the occurrence of various diseases. The study on Wangfang and the like on the eating behaviors of 180 children proves that 53.3 percent of children have the behavior of food selection, and 39.4 percent of children have 1 to 3 kinds of food which are not eaten; food is often uninteresting and anorexia in 28.9% of children.
Anorexia occurs mainly in the pediatric population of 1-6 years of age. The disease is mainly manifested by anorexia and food consumption reduction, which further cause malnutrition and deficiency of vitamins and trace elements, seriously affect growth and development and possibly cause other diseases, such as anemia, rickets, hypoevolutism and the like, and the clinical application of the disease is very important.
The disease has more causes, and the traditional Chinese medicine considers that the spleen is often insufficient in the period of children, and in addition, the food is not self-regulated, choking, monophagia, snacks are eaten well, and the hunger and satiety are caused by untimely eating; most parents lack children-care knowledge, excessively favor infants, and are not restricted in diet, so that the spleen and stomach are disarmed and abnormal in reception, so that the appetite is poor and anorexia is formed for a long time. Food retention in the body can injure the spleen and stomach, and the infant is weak and can cause other diseases. When the spleen and stomach are damaged and the original qi cannot be nourished by food essence, the disease will be caused by the deficiency of spleen and stomach, which leads to anorexia and anorexia of the infant patients. If anorexia is not cured for a long time and nutrition is insufficient, diseases such as malnutrition, anemia and the like can be generated.
Food stagnation, also known as impaired food and food retention, is one of the common spleen diseases in pediatrics, and is characterized by indigestion, abdominal distension, indigestion, eructation with fetid odor and acid regurgitation, stool odor or constipation. The western medicine does not clearly indicate which disease the food belongs to, and the medical profession is inconsistent at present, and the literature has some symptoms such as indigestion in children, anorexia or functional dyspepsia. The western medicine mainly treats the disease from the following aspects: (1) actively treating primary diseases; (2) correcting the deficiency of trace elements, such as zinc deficiency, and orally taking zinc gluconate; (3) digestive aids, such as gastric enzyme cocktail or yeast; (4) gastric motility agents such as morpholine and the like; (5) hormonal therapy, prednisone, small doses of insulin, and the like. The treatment methods mainly aim at symptomatic treatment and symptom improvement, and can not fundamentally treat the problem of insufficient gastrointestinal motility of children patients.
In view of this, the invention is particularly proposed.
Disclosure of Invention
The invention aims to provide a composition for regulating intestines and stomach and promoting appetite, a beverage and a preparation method thereof so as to solve the technical problems.
The invention is realized by the following steps:
the composition for regulating intestines and stomach and promoting appetite comprises the following raw materials in parts by weight: 10.8-14.8 parts of malt powder, 8.4-12.4 parts of hawthorn powder, 2.3-6.3 parts of endothelium corneum gigeriae galli powder, 7.3-11.3 parts of orange peel powder, 4.4-8.4 parts of radish seed powder, 1.2-5.2 parts of yam powder, 0.7-1.5 parts of poria cocos powder and 0.1-0.18 part of zinc gluconate.
The inventor creatively provides a composition for regulating intestines and stomach and promoting appetite, and the composition has the following functions and efficacies: promoting digestion, invigorating spleen, promoting appetite, promoting salivation, regulating spleen and stomach function, and improving appetite.
Wherein the malt flour and the hawthorn powder are monarch drugs, the malt can promote qi circulation and promote digestion, and the hawthorn is used for indigestion; orange peel and radish seed powder are used as ministerial drugs, and can eliminate food retention and eliminate fullness, promote digestion and eliminate stagnation, and strengthen stomach and promote digestion; the Chinese yam and the endothelium corneum gigeriae galli are adjuvant drugs, can tonify qi, nourish yin and invigorate spleen, and have the effects of assisting monarch and minister drugs. Rhizoma Dioscoreae for invigorating qi and yin is added for spleen qi weakness; poria is used as a messenger drug to invigorate the spleen and replenish qi, and orange peel is used as an assistant drug to enliven the spleen and harmonize the stomach, promote qi circulation and stagnation and assist qi circulation and transportation.
The formula raw materials provided by the invention are obtained through scientific and rigorous argumentation, and the active ingredients (total flavonoids) in the beverage are superior to common beverages on the market by accurately positioning the reasons of monophagia and anorexia of people.
The raw materials selected by the invention are all suitable for long-term taking and have the functions of promoting appetite, promoting the secretion of saliva or body fluid and regulating spleen and stomach, and are harmless to human body and have obvious effect.
The malt flour has the effects of promoting digestion, relieving flatulence, relieving epigastric distention, activating spleen, stimulating appetite, and invigorating qi and deficiency. The malt is also called malt, barley collection, wheat millet and barley hair, and is prepared by germinating and drying mature fruits of barley of Gramineae. It has effects in promoting qi circulation, resolving food stagnation, invigorating spleen, stimulating appetite, and relieving lactation. Can be used for treating dyspepsia, abdominal distention and pain, and anorexia due to spleen deficiency. The raw malt has the effects of strengthening spleen and stomach, and is used for treating spleen deficiency, anorexia and milk stagnation; stir-baked malt moves qi and eliminates food stagnation; the charred malt is used for promoting digestion and resolving stagnation, is used for indigestion and abdominal distension and pain, and is a common Chinese medicine for promoting digestion in clinic. The malt contains amylase, which can decompose starch into maltose for absorption by body. According to medical records, the pancreatic amylase activator is extracted from the water decoction of the roasted malt, and through identification and verification, the extract does not contain other components, is only a mixture of a large amount of calcium nitrate and a small amount of sodium chloride, and has a remarkable activation effect on the pancreatic amylase, so that the nitrate ions and the chloride ions are the main components contributing to digestion of the water decoction of the roasted malt.
The hawthorn powder is used for treating meat food stagnation, gastric cavity fullness and hyperlipidemia. The hawthorn powder has the following effects: promoting digestion and invigorating stomach, can be used for various food stagnation, especially for the treatment of greasy, soft and calculus stagnation, and can be used for treating abdominal distention, belch, acid regurgitation, abdominal pain and diarrhea due to food stagnation; promoting qi circulation and removing blood stasis: it can be used for diarrhea, dysentery, abdominal pain, hernia and abdominal pain after stir-baked into scorched powder. After the hawthorn is fried, the functions of promoting blood circulation and removing blood stasis are weakened, and the effects of invigorating stomach and promoting digestion are enhanced, but the fried hawthorn still has the effects of promoting blood circulation and removing blood stasis. The parched fructus crataegi has good digestion effect on meat. The parched fructus crataegi has effects of reducing blood lipid and cholesterol.
Endothelium corneum Gigeriae Galli powder can be used for treating dyspepsia, emesis, dysentery, infantile malnutrition, enuresis, nocturnal emission, stranguria with stone, pain, gallbladder distention, and hypochondriac pain. Modern researches show that the endothelium corneum gigeriae galli mainly contains proteins (pepsin, amylase, keratin and the like), polysaccharides, amino acids (the total amount of the amino acids is 86.924%, wherein the essential amino acids account for 30.264%, and the umami amino acids account for 43.018%) and the like, and has potential biological activity in the aspects of stimulating gastrointestinal movement, improving blood fat and hemorheology and protecting cardiac muscle. The endothelium corneum gigeriae galli powder can be orally taken clinically, can treat a plurality of diseases and symptoms, and particularly correct digestive system diseases of patients caused by weakness of spleen and stomach functions, such as inappetence, emaciation, constipation and even infantile malnutrition of children, and is suitable for being taken by mixing with endothelium corneum gigeriae galli powder.
Tangerine peel powder is used for treating abdominal distention, anorexia, vomiting and diarrhea, cough, excessive phlegm, etc. The orange peel contains rich effective components, mainly comprising flavonoids (hesperidin, tangerine peel polymethoxyflavone, nobiletin), volatile oils (limonene), alkaloids (synephrine), etc. Hesperidin, neohesperidin and naringin are contained in the peel of citrus plants at high content, polymethoxylated flavone is a special component of oranges, and the peel of the citrus plants also contains a small amount of carotenoid, vitamin C, trace elements and the like. The pericarpium Citri Tangerinae powder is helpful for digestion, and has effects of activating qi-flowing, invigorating spleen, eliminating dampness, eliminating phlegm, removing greasy, keeping fragrance, lowering adverse qi, relieving vomit, diminishing inflammation, and reducing urine volume.
The radish seed powder has the effects of promoting gastrointestinal motility, helping digestion, relieving dyspepsia, removing flatulence and activating stagnancy, particularly has the advantages of relieving food stagnation in area, and the active part of the radish seed powder for promoting gastrointestinal motility can increase the MTL content in the blood plasma of rats.
The rhizoma Dioscoreae powder is used for treating spleen deficiency, anorexia, chronic diarrhea, etc. The yam flour contains abundant proteins, amino acids essential to human bodies, various trace elements, polysaccharide, allantoin, saponin and other various nutritional ingredients and functional factors, and has the effects of reducing blood sugar, reducing blood fat, resisting oxidation, resisting aging, enhancing immunity, resisting tumors and the like.
Poria powder can be used for treating edema, oliguria, phlegm and fluid retention, dizziness, palpitation, spleen deficiency, anorexia, loose stool, and diarrhea. Pachyman has effects of enhancing organism immunity, inhibiting tumor growth, resisting spleen enlargement and thymus gland atrophy, and enhancing humoral immunity and cellular immunity.
The zinc gluconate is white crystalline or granular powder; no bad smell. Is suitable for treating zinc deficiency diseases such as infantile anorexia, various skin acne, recurrent aphthous ulcer, etc. Participate in the synthesis and activation of various zinc-containing enzymes and zinc-dependent enzymes, play an important physiological role in protein synthesis, nucleic acid synthesis and absorption and digestion of intestinal proteins, and can promote growth and development. The parakeratosis of buccal mucosa epithelial cell is prevented by synthesizing gustatory essence in taste bud to maintain normal appetite and taste.
Most of the raw materials provided by the invention are medicinal and edible raw materials, so that the supply dosage of effective functional components is ensured. The beverage is filled by mixing the zinc gluconate, so that the taste is ensured, the worry of gastrointestinal tract digestion problems caused by child anorexia and food accumulation is relieved, the nutrition requirement of children is ensured, and the children are healthily grown up to protect driving and navigation.
In a preferred embodiment of the present invention, the raw materials include: 11.8-13.8 parts of malt powder, 9.4-11.4 parts of hawthorn powder, 3.3-5.3 parts of endothelium corneum gigeriae galli powder, 8.3-10.3 parts of orange peel powder, 5.4-7.4 parts of radish seed powder, 2.2-4.2 parts of yam powder, 0.9-1.3 parts of poria cocos powder and 0.12-0.16 part of zinc gluconate.
In a preferred embodiment of the present invention, the raw materials include: 12.8 parts of malt powder, 10.4 parts of hawthorn powder, 4.3 parts of endothelium corneum gigeriae galli powder, 9.3 parts of orange peel powder, 6.4 parts of radish seed powder, 3.2 parts of yam powder, 1.1 parts of poria cocos powder and 0.14 part of zinc gluconate.
In the preferred embodiment of the invention, the raw materials further comprise 88.8-128.8 parts of white granulated sugar.
A beverage for regulating intestines and stomach and promoting appetite comprises the following raw materials in parts by weight: 10.8-14.8 parts of malt powder, 8.4-12.4 parts of hawthorn powder, 2.3-6.3 parts of endothelium corneum gigeriae galli powder, 7.3-11.3 parts of orange peel powder, 4.4-8.4 parts of radish seed powder, 1.2-5.2 parts of yam powder, 0.7-1.5 parts of tuckahoe powder, 0.1-0.18 part of zinc gluconate, 88.8-128.8 parts of white granulated sugar and water.
The raw material proportion of the beverage provided by the invention is based on Chinese pharmacopoeia and traditional ancient prescription, and through multiple experimental demonstration, hawthorn powder, malt powder, endothelium corneum gigeriae galli powder, orange peel powder, radish seed powder, yam powder and tuckahoe powder are selected as main active substance sources, so that the problem of anorexia and monophagia of children is solved in seven aspects of removing food retention, tonifying spleen, promoting digestion, stimulating appetite, eliminating fullness, tonifying qi and invigorating qi.
A method of preparing a beverage comprising: weighing malt flour, hawthorn powder, endothelium corneum gigeriae galli powder, orange peel powder, radish seed powder, Chinese yam powder, poria cocos powder and zinc gluconate according to a formula, placing the materials into a container, adding water and stirring to obtain a raw material pasty solution, weighing 88.8-128.8 parts of white granulated sugar, placing the white granulated sugar into 550 parts of 450-doped water for boiling, cooling, mixing the raw material pasty solution with the boiled white granulated sugar solution, and heating.
In a preferred embodiment of the invention, the preparation method comprises the steps of putting 88.8-128.8 parts of white granulated sugar into 550 parts of water, heating while stirring, wherein the boiling time is more than 30 minutes; preferably, cooling to 45. + -. 5 ℃.
In a preferred embodiment of the application of the invention, 21-41 parts of concentrated hawthorn juice is added when the raw material pasty solution is mixed with the boiled white granulated sugar solution; preferably, the heating temperature is 80-90 ℃ and the heating time is 8-12 minutes.
The heating temperature is too low, which can result in the reduction of the content of the obtained total flavonoids. Tests show that the taste is not obviously influenced by the temperature rise. And the increase of the temperature is beneficial to the improvement of the antioxidant activity of the flavone.
Adopts fried hawthorn to invigorate the spleen and dissolve food, and adds hawthorn concentrated juice at the same time. The functions of raw hawthorn for helping digestion and assisting stomach and strengthening digestion are utilized, and meanwhile, the hawthorn concentrated juice is sour in taste and sour and sweet in taste to transform yin, so that the hawthorn concentrated juice also has the effects of stimulating appetite and promoting the secretion of saliva or body fluid.
In a preferred embodiment of the invention, the concentrated hawthorn juice is added, heated and cooled, and then the hawthorn essence is added and the volume is fixed. The hawthorn juice and the hawthorn flavor essence are used as flavoring agents, are sour, sweet and delicious, and are widely popular among children.
Preferably, ultrafiltration is performed after constant volume. Filtering by ultrafiltration to remove impurities.
And (4) monitoring the content change of soluble solids of the sugar solution, the materials before and after filtration by using a saccharimeter, and supplementing sugar if the content change exceeds 0.2%.
The material is monitored by a pH meter before filtration, before homogenization and after sterilization, wherein the pH must be less than 4.0, preferably less than 3.5, and the shelf life of the material can be maintained for 15-30min at 100-121 ℃ under the above conditions. The content of total flavonoids in the beverage is controlled to be 1.024mg/ml-1.424 mg/ml.
In a preferred embodiment of the application of the invention, the constant volume process further comprises filling, sterilizing and packaging; preferably, the sterilization temperature is 100-121 ℃, and the sterilization time is 15-30 min.
Subpackaging by a filling machine, and then sterilizing. And packaging according to the packaging specification after sterilization, stacking, orderly boxing, sealing by using an adhesive tape, and preparing for warehousing. The quality inspector supervises the whole packaging process. The packaging quality of the product and the quality of the used packaging material must be checked at any time during the packaging process.
The invention has the following beneficial effects:
the invention provides a composition for regulating intestines and stomach and promoting appetite, a beverage and a preparation method thereof, wherein the raw material proportion provided by the invention is based on Chinese pharmacopoeia and traditional ancient prescription, and through multiple experimental demonstration, hawthorn powder, malt powder, endothelium corneum gigeriae galli powder, tangerine peel powder, radish seed powder, yam powder and tuckahoe powder are selected as main active substance sources, so that the problem of anorexia and monophagia of children is solved in seven aspects of removing food retention, strengthening spleen, promoting digestion, promoting appetite, eliminating fullness, tonifying qi and assisting qi. The beverage for regulating intestines and stomach and promoting appetite provided by the invention can fundamentally solve the problem of insufficient gastrointestinal motility of children patients, and the active ingredients (total flavonoids) in the beverage are superior to common beverages on the market.
Drawings
In order to more clearly illustrate the technical solutions of the embodiments of the present invention, the drawings needed to be used in the embodiments will be briefly described below, it should be understood that the following drawings only illustrate some embodiments of the present invention and therefore should not be considered as limiting the scope, and for those skilled in the art, other related drawings can be obtained according to the drawings without inventive efforts.
FIG. 1 is a graph comparing the digestion effects;
FIG. 2 is a graph showing the effect of ameliorating anorexia;
FIG. 3 is a graph comparing mouthfeel;
fig. 4 is a standard curve of rutin.
Detailed Description
In order to make the objects, technical solutions and advantages of the embodiments of the present invention clearer, the technical solutions in the embodiments of the present invention will be clearly and completely described below. The examples, in which specific conditions are not specified, were conducted under conventional conditions or conditions recommended by the manufacturer. The reagents or instruments used are not indicated by the manufacturer, and are all conventional products available commercially.
The features and properties of the present invention are described in further detail below with reference to examples.
Example 1
The embodiment provides a composition for regulating and promoting appetite of intestines and stomach, a beverage and a preparation method thereof, wherein the composition for regulating and promoting appetite of the intestines and stomach comprises the following raw materials in parts by weight: 12.8g of malt powder, 10.4g of hawthorn powder, 4.3g of endothelium corneum gigeriae galli powder, 9.3g of orange peel powder, 6.4g of radish seed powder, 3.2g of yam powder, 1.1g of poria cocos powder and 0.14g of zinc gluconate.
The preparation method of the beverage for regulating intestines and stomach and promoting appetite comprises the following steps:
respectively weighing malt flour, hawthorn powder, endothelium corneum gigeriae galli powder, tangerine peel powder, radish seed powder, yam powder, tuckahoe powder and zinc gluconate according to the formula, placing the materials into a container, adding a proper amount of purified water, and stirring the materials into paste to obtain a raw material paste solution.
Then, 108.8g of white granulated sugar is accurately weighed, 500g of purified water is added for boiling, the mixture is uniformly stirred while being heated, and after the mixture is boiled for 30 minutes, the mixture is cooled to 45 +/-5 ℃ for later use.
Then 21g of concentrated hawthorn juice and the raw material pasty solution are respectively added into the white granulated sugar solution and stirred uniformly. Heating to 85 deg.C, maintaining for 10min, cooling to room temperature, adding 0.8g fructus crataegi essence, adding purified water to a constant volume of 1000ml, stirring, and ultrafiltering with microporous membrane of 0.08 μm.
Finally, the beverage was dispensed into vials by a filling machine and sterilized at 100 ℃ for 30 min.
Example 2
The embodiment provides a beverage for regulating intestines and stomach and promoting appetite and a preparation method thereof, and the beverage comprises the following raw materials in parts by weight: 10.8 parts of malt powder, 8.4 parts of hawthorn powder, 2.3 parts of endothelium corneum gigeriae galli powder, 7.3 parts of orange peel powder, 4.4 parts of radish seed powder, 1.2 parts of yam powder, 0.7 part of poria cocos powder and 0.1 part of zinc gluconate. The preparation method comprises the following steps:
weighing malt flour, hawthorn powder, endothelium corneum gigeriae galli powder, tangerine peel powder, radish seed powder, yam powder, tuckahoe powder and zinc gluconate according to a formula, placing the materials into a container, adding a proper amount of purified water, and stirring the materials into paste to obtain a raw material paste solution.
Then, 88.8 parts of white granulated sugar is accurately weighed, 480 parts of purified water is added for boiling, the mixture is uniformly stirred while being heated, and after the mixture is boiled for 30 minutes, the mixture is cooled to 45 +/-5 ℃ for later use.
And respectively adding 25g of the concentrated hawthorn juice and the raw material pasty solution into the white granulated sugar solution, and uniformly stirring. Heating to 85 deg.C, maintaining for 10min, cooling to room temperature, adding fructus crataegi essence, adding purified water to desired volume, stirring, and ultrafiltering.
Finally, the beverage was subpackaged into vials by a filling machine and sterilized at 100 ℃ for 30 min.
Example 3
The embodiment provides a beverage for regulating intestines and stomach and promoting appetite and a preparation method thereof, and the beverage comprises the following raw materials in parts by weight: 14.8 parts of malt powder, 12.4 parts of hawthorn powder, 6.3 parts of endothelium corneum gigeriae galli powder, 11.3 parts of orange peel powder, 8.4 parts of radish seed powder, 5.2 parts of yam powder, 1.5 parts of poria cocos powder and 0.18 part of zinc gluconate. The preparation method of the beverage comprises the following steps:
weighing malt flour, hawthorn powder, endothelium corneum gigeriae galli powder, tangerine peel powder, radish seed powder, yam powder, poria cocos powder and zinc gluconate according to a formula, placing the mixture into a container, adding a proper amount of purified water, and stirring the mixture into paste to obtain a raw material paste solution.
Then, 108.8 parts of white granulated sugar is accurately weighed, 520 parts of purified water is added for boiling, the mixture is uniformly stirred while being heated, and after the mixture is boiled for 30 minutes, the mixture is cooled to 45 +/-5 ℃ for later use.
And respectively adding 35g of concentrated hawthorn juice and the raw material pasty solution into the white granulated sugar solution, and uniformly stirring. Heating to 85 deg.C, maintaining for 10min, cooling to room temperature, adding fructus crataegi essence, adding purified water to desired volume, stirring, and ultrafiltering.
Finally, the beverage was dispensed into small bottles by a filling machine and sterilized at 100 ℃ for 30 min.
Example 4
The embodiment provides a beverage for regulating intestines and stomach and promoting appetite and a preparation method thereof, and the beverage comprises the following raw materials in parts by weight: 12.8 parts of malt powder, 10.4 parts of hawthorn powder, 4.3 parts of endothelium corneum gigeriae galli powder, 9.3 parts of orange peel powder, 6.4 parts of radish seed powder, 3.2 parts of yam powder, 1.1 parts of poria cocos powder and 0.14 part of zinc gluconate. The preparation method comprises the following steps:
weighing malt flour, hawthorn powder, endothelium corneum gigeriae galli powder, tangerine peel powder, radish seed powder, yam powder, poria cocos powder and zinc gluconate according to a formula, placing the mixture into a container, adding a proper amount of purified water, and stirring the mixture into paste to obtain a raw material paste solution.
Then, 108.8 parts of white granulated sugar is accurately weighed, 500 parts of purified water is added for boiling, the mixture is uniformly stirred while being heated, and after the mixture is boiled for 30 minutes, the mixture is cooled to 45 +/-5 ℃ for later use.
And respectively adding the concentrated 27g of hawthorn juice and the raw material pasty solution into the white granulated sugar solution, and uniformly stirring. Heating to 80 deg.C, maintaining for 8 min, cooling to room temperature, adding fructus crataegi essence, adding purified water to desired volume, stirring, and ultrafiltering.
Finally, the beverage was dispensed into vials by a filling machine and sterilized at 100 ℃ for 30 min.
Example 5
The embodiment provides a beverage for regulating intestines and stomach and promoting appetite and a preparation method thereof, and the beverage comprises the following raw materials in parts by weight: 12.8 parts of malt powder, 10.4 parts of hawthorn powder, 4.3 parts of endothelium corneum gigeriae galli powder, 9.3 parts of orange peel powder, 6.4 parts of radish seed powder, 3.2 parts of yam powder, 1.1 parts of poria cocos powder and 0.14 part of zinc gluconate. The preparation method comprises the following steps:
weighing malt flour, hawthorn powder, endothelium corneum gigeriae galli powder, tangerine peel powder, radish seed powder, yam powder, tuckahoe powder and zinc gluconate according to a formula, placing the materials into a container, adding a proper amount of purified water, and stirring the materials into paste to obtain a raw material paste solution.
Then, 108.8 parts of white granulated sugar is accurately weighed, 500 parts of purified water is added for boiling, the mixture is uniformly stirred while being heated, and after the mixture is boiled for 30 minutes, the mixture is cooled to 45 +/-5 ℃ for later use.
And respectively adding 40g of concentrated hawthorn juice and the raw material pasty solution into the white granulated sugar solution, and uniformly stirring. Heating to 90 deg.C, maintaining for 12 min, cooling to room temperature, adding fructus crataegi essence, adding purified water to desired volume, stirring, and ultrafiltering.
Finally, the beverage was dispensed into vials by a filling machine and sterilized at 100 ℃ for 30 min.
The invention also provides a comparative example to further observe and verify the effects and efficacies of the invention.
Comparative example 1:
the raw material composition of the beverage for regulating intestines and stomach and promoting appetite is the same as that in the embodiment 1 of the invention, but the difference between the raw material composition and the raw material composition is that the radish seed powder in the embodiment 1 is replaced by the immature bitter orange powder, and the preparation method of the beverage is the same.
The experimental process comprises the following steps: in 2020, 4 days in month 5 to 18 days in month 5, the conditions of the selected experimental subjects are as follows: the staff of the enterprise, aged 22-55 years, had anorexia and food retention habits, and had 100 total numbers. The experimental subjects were randomly divided into two groups, namely a control group and an experimental group, wherein each group contains 50 patients, the control group takes the formula containing the immature bitter orange powder, and the experimental group takes the formula of the invention in example 1. In two groups of people, the beverage has the same dosage of 2 bottles/day and 50 mL/bottle, and the effect is observed after the beverage is continuously taken for 14 days.
The diet improvement effect of the experimental group and the control group was counted, and the statistical results are shown in fig. 1. The judgment standard of the curative effect is as follows:
remarkably: the symptoms completely disappeared;
the method has the following advantages: partial disappearance of symptoms;
and (4) invalidation: no improvement in symptoms.
And (5) performing curative effect feedback in a questionnaire survey mode.
As can be seen from fig. 1, the effect of the experimental group as a whole is better than that of the control group, and particularly, the effect of improving food retention is remarkably improved, the efficiency of improving food retention and anorexia is 90.91% and 88.24%, respectively, while the efficiency of improving food retention and anorexia is only 79.31% and 76.19% in the control group, and thus, the effect of promoting digestion of the beverage of example 1 of the present invention is better than that of comparative example 1.
Comparative example 2
The raw material composition of the beverage for regulating intestines and stomach and promoting appetite is similar to that of the beverage in the embodiment 1 of the invention, and the difference is only that the fructus amomi powder is adopted to replace the dried orange peel powder in the embodiment 1, and the preparation method of the beverage is the same.
The experimental process comprises the following steps: in 2020, 25 days in month 5 to 8 days in month 6, the conditions of the selected experimental objects are as follows: the staff of the enterprise, aged 22-55 years, had symptoms of anorexia, and the total number of the staff was 100. The subjects were randomly divided into two groups, a control group, which received a beverage made from a formula containing fructus amomi powder, and an experimental group, which received a beverage made from a formula according to example 1 of the present invention, with 50 individuals per group. In two groups, the beverage has the same dosage, and the effect is observed after continuously taking for 14 days.
The effect of the experimental group and the control group after being taken by people is shown in figure 2, and as can be seen from figure 2, the beverage containing the amomum powder and the beverage containing the tangerine peel powder can improve the symptom of inappetence, but the effect of the experimental group is better than that of the control group, and the improvement efficiency is respectively 96% and 90%.
Taste comparison fig. 3 shows that the taste of the experimental group is better and more acceptable to drinkers, as seen from the taste comparison fig. 3. It can be seen that the beverage prepared by the formulation provided in example 1 of the present invention has better digestion promoting effect and mouthfeel than those of the beverage prepared by the formulation in comparative example 2.
Comparative example 3: the invention discloses a beverage for regulating intestines and stomach and promoting appetite and a preparation method thereof, wherein the raw material composition is the same as that of the beverage in the embodiment 1, and the difference is that in the comparative example, concentrated hawthorn juice and raw material pasty solution are respectively added into white granulated sugar solution, the mixture is uniformly stirred and heated to 50 ℃ for 10 minutes, and other process steps are not changed.
The experimental process comprises the following steps: two experiments are carried out and respectively marked as an experimental group and a control group, the control group carries out beverage preparation according to the formula and the process of the comparative example 3, the experimental group carries out beverage preparation according to the formula and the preparation process of the example 1, and finally, the content of the total flavone in the two groups of beverages is measured.
The method for measuring the content of the total flavonoids in the beverage comprises the following steps:
preparing a standard solution: accurately weighing 20.8mg of rutin reference substance, placing in a 100mL volumetric flask, adding 70% ethanol to dissolve and dilute to scale, and shaking up.
Drawing a standard curve: accurately weighing 0, 1.0, 2.0, 3.0, 4.0 and 5.0mL of reference solution, respectively placing into 25mL colorimetric tubes, adding 0.7mL of 5% NaNO2Shaking, standing for 5min, adding 0.7mL 10% Al (NO)3)3Standing for 6min, adding 5mL of 1mol/LNaOH, shaking up, fixing the volume to the scale mark with 70% ethanol, (replacing distilled water as blank control), standing for 10min, measuring absorbance at 510nm, and drawing a standard curve with the absorbance as ordinate and the standard concentration as abscissa.
And (3) sample liquid determination: accurately weighing 5g of prepared finished beverage in a 50mL volumetric flask, adding 70% ethanol to a constant volume to a scale, preparing a sample solution with a concentration of 0.1g/mL for later use (whether dilution is needed or not and the dilution multiple is within a range of 0.2-0.8 according to the measured light absorption value), sucking 5mL of diluted sample solution in a 25mL colorimetric tube, adding 0.7mL of 5% NaNO into the colorimetric tube2Shaking, standing for 5min, adding 0.7mL 10% Al (NO)3)3Stand for 6mAfter in, 5mL of NaOH with the concentration of 1mol/L is added, the mixture is shaken up, the volume is determined to the scale mark by 70 percent ethanol, and the mixture is placed for 10min and then the absorbance is measured at 510 nm. The total flavone of the beverage is expressed by the relative amount of rutin, and the experiments are repeated for 3 times.
The standard curve obtained was Y-10.883X +0.00003, R2The standard curve is shown in fig. 4, 0.9962. The total flavonoids in the beverage were calculated by multiplying the beverage solution by the dilution factor.
After three repeated tests, the following results were obtained:
table 1 total flavone content.
Group of 1 2 3 Mean value (mg/ml)
Control group 1.188 1.187 1.19 1.188
Experimental group 1.223 1.224 1.225 1.224
The comparison results in table 1 show that the preparation process is more excellent when the flavone content in the experimental group is higher than that in the control group, and thus, the preparation process in example 1 of the present invention is more excellent than that in comparative example 3, and the obtained active ingredient has a higher content.
Through experimental demonstration of the above examples and comparative examples, it can be shown that the beverage for regulating intestines and stomach and promoting appetite provided by the invention has the advantages of high flavone content, obvious digestion promoting effect and good taste.
The above description is only a preferred embodiment of the present invention and is not intended to limit the present invention, and various modifications and changes may be made by those skilled in the art. Any modification, equivalent replacement, or improvement made within the spirit and principle of the present invention should be included in the protection scope of the present invention.

Claims (10)

1. The composition for regulating intestines and stomach and promoting appetite is characterized by comprising the following raw materials in parts by weight: 10.8-14.8 parts of malt powder, 8.4-12.4 parts of hawthorn powder, 2.3-6.3 parts of endothelium corneum gigeriae galli powder, 7.3-11.3 parts of orange peel powder, 4.4-8.4 parts of radish seed powder, 1.2-5.2 parts of yam powder, 0.7-1.5 parts of poria cocos powder and 0.1-0.18 part of zinc gluconate.
2. The composition of claim 1, wherein the starting material comprises: 11.8-13.8 parts of malt powder, 9.4-11.4 parts of hawthorn powder, 3.3-5.3 parts of endothelium corneum gigeriae galli powder, 8.3-10.3 parts of orange peel powder, 5.4-7.4 parts of radish seed powder, 2.2-4.2 parts of yam powder, 0.9-1.3 parts of poria cocos powder and 0.12-0.16 part of zinc gluconate.
3. The composition of claim 2, wherein the starting materials comprise: 12.8 parts of malt powder, 10.4 parts of hawthorn powder, 4.3 parts of endothelium corneum gigeriae galli powder, 9.3 parts of orange peel powder, 6.4 parts of radish seed powder, 3.2 parts of yam powder, 1.1 parts of poria cocos powder and 0.14 part of zinc gluconate.
4. The composition of claim 2, wherein the raw materials further comprise 88.8-128.8 parts of white granulated sugar.
5. The beverage for regulating intestines and stomach and promoting appetite is characterized by comprising the following raw materials in parts by weight: 10.8-14.8 parts of malt powder, 8.4-12.4 parts of hawthorn powder, 2.3-6.3 parts of endothelium corneum gigeriae galli powder, 7.3-11.3 parts of orange peel powder, 4.4-8.4 parts of radish seed powder, 1.2-5.2 parts of yam powder, 0.7-1.5 parts of tuckahoe powder, 0.1-0.18 part of zinc gluconate, 88.8-128.8 parts of white granulated sugar and water.
6. A method for preparing a beverage according to claim 5, characterized in that it comprises: weighing malt flour, hawthorn powder, endothelium corneum gigeriae galli powder, orange peel powder, radish seed powder, Chinese yam powder, poria cocos powder and zinc gluconate according to a formula, placing the materials into a container, adding water and stirring to obtain a raw material pasty solution, weighing 88.8-128.8 parts of white granulated sugar, placing the raw material pasty solution into water for boiling, mixing the raw material pasty solution with the boiled white granulated sugar solution, and heating.
7. The method for preparing the beverage as claimed in claim 6, wherein the method comprises boiling 88.8-128.8 parts of white granulated sugar in 550 parts of water of 450 parts, stirring while heating, wherein the boiling time is more than 30 minutes; preferably, the mixture is cooled to 45 +/-5 ℃ after being boiled.
8. The method for preparing a beverage according to claim 6, wherein 21-41 parts of concentrated hawthorn juice is added when the raw material pasty solution is mixed with the boiled white granulated sugar solution; preferably, the heating temperature is 80-90 ℃ and the heating time is 8-12 minutes.
9. The method for preparing a beverage according to claim 8, wherein the concentrated hawthorn juice is added, heated, cooled, added with the hawthorn-flavored essence and subjected to volume fixing;
preferably, ultrafiltration is performed after constant volume.
10. The method for preparing the beverage according to claim 9, wherein the steps of filling, sterilizing and packaging are further included after the volume fixing; preferably, the sterilization temperature is 100-121 ℃, and the sterilization time is 15-30 min.
CN202010735201.1A 2020-07-27 2020-07-27 Composition and beverage for regulating intestines and stomach and promoting appetite and preparation method thereof Pending CN111700198A (en)

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Application publication date: 20200925