CN111686293A - Composite dressing and negative pressure drainage device prepared from same - Google Patents
Composite dressing and negative pressure drainage device prepared from same Download PDFInfo
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- CN111686293A CN111686293A CN202010561894.7A CN202010561894A CN111686293A CN 111686293 A CN111686293 A CN 111686293A CN 202010561894 A CN202010561894 A CN 202010561894A CN 111686293 A CN111686293 A CN 111686293A
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- negative pressure
- composite dressing
- drainage device
- dressing
- negative
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- 229920000728 polyester Polymers 0.000 claims description 28
- 238000007789 sealing Methods 0.000 claims description 22
- 239000004373 Pullulan Substances 0.000 claims description 20
- 229920001218 Pullulan Polymers 0.000 claims description 20
- 238000002156 mixing Methods 0.000 claims description 20
- 235000019423 pullulan Nutrition 0.000 claims description 20
- 239000004744 fabric Substances 0.000 claims description 19
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- 238000002844 melting Methods 0.000 claims description 15
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Images
Classifications
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- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/18—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing inorganic materials
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- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/22—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
- A61L15/26—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds; Derivatives thereof
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- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/22—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
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- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/42—Use of materials characterised by their function or physical properties
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- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
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- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/42—Use of materials characterised by their function or physical properties
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- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/10—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing inorganic materials
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- A61L2300/104—Silver, e.g. silver sulfadiazine
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- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
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- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/404—Biocides, antimicrobial agents, antiseptic agents
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- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
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- A61L2400/00—Materials characterised by their function or physical properties
- A61L2400/12—Nanosized materials, e.g. nanofibres, nanoparticles, nanowires, nanotubes; Nanostructured surfaces
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- General Health & Medical Sciences (AREA)
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- Chemical Kinetics & Catalysis (AREA)
- Nonwoven Fabrics (AREA)
Abstract
The invention relates to the field of medical instruments, and provides a composite dressing and a negative pressure drainage device prepared from the composite dressing. The drainage device can meet the requirements of different wound positions, is convenient to operate and low in cost, and the composite dressing has high biological safety, flexibility, high elasticity and excellent permeability and has the effect of promoting wound healing.
Description
Technical Field
The invention relates to the field of medical instruments, in particular to a composite dressing and a negative pressure drainage device prepared from the same.
Background
The closed negative pressure drainage technology adopts foam dressing with drainage tube to cover or fill the wound surface with skin and soft tissue defect, uses transparent sealing film to seal the dressing to make the whole system become closed space, finally uses flexible tube to connect the drainage tube outlet to negative pressure absorber, and can regulate negative pressure to promote wound surface healing.
The foam dressing needs to have good permeability so as to ensure that metabolites such as tissue exudate, purulent blood, protein and the like can be normally sucked out, and meanwhile, the foam dressing needs to have good biocompatibility when being in contact with a wound so as to promote the growth and healing of the granulation of the wound.
There are two types of foam dressings commonly used: the foam polyvinyl alcohol and the polyurethane foam materials are respectively used, the production cost of the foam polyvinyl alcohol is high, the process for manufacturing the porous structure is complex, China mainly depends on import, and in addition, the foam polyvinyl alcohol is easy to oxidize and harden to cause the foam to lose elasticity and be scrapped; the polyurethane foam material is a reticular open type hydrophilic polyurethane foam structure with the aperture range of 400-600 microns, a large number of holes are beneficial to drainage of a wound surface, but because the polyurethane foam material is a hidden trouble of certain toxic and side effects caused by solvent residues generated by foaming of chemical raw materials, the foam dressing also has the problems of yellowing and hardening in different degrees in a storage period. The negative pressure drainage device that importers produced is mostly fixed specification and model, hardly satisfies the needs and the price of different wound positions very expensive, consequently, develops a low-cost and convenient to use's negative pressure drainage device and is especially important.
Disclosure of Invention
In view of the defects in the prior art, a first object of the present invention is to provide a method for preparing a composite dressing, wherein the prepared composite dressing has the advantages of high biological safety, high elasticity, flexibility and excellent permeability, and the composite dressing has the advantage of promoting wound healing.
In order to achieve the purpose, the invention provides the following technical scheme:
a preparation method of the composite dressing comprises the following steps:
s1, compounding a nano-silver-containing solution on viscose fibers and elastic polyester staple fibers, mixing the viscose fibers and the elastic polyester staple fibers according to a mass ratio of 1: 1-2.5, and carding, unfolding and continuously lapping to form a fiber web;
s2, arranging low-melting polyester staple fibers on the fiber web, and folding the fiber web into an upright continuous superposed state through a cotton folding device to form a plurality of side-by-side 3D upright cotton units;
and S3, heating the obtained 3D upright cotton unit in a hot melting environment for 20-40 min at the baking temperature of 160-200 ℃, and cutting to obtain the composite dressing.
Further, in step S1, a pullulan solution is further added during the mixing process.
Furthermore, the mass concentration of the pullulan solution is 1-8 ug/ml.
Further, the composite dressing is obtained by pressurized water treatment and contains 30-40% of water by mass.
The inventor discovers that when the pullulan solution with the mass concentration of 1-8 ug/ml is added into the composite dressing, the wound healing can be promoted, the biological safety is good, the elasticity is good, the composite dressing is not hard easily, and the performance is softer; the inventor surprisingly discovers that when the pullulan solution is added into the preparation process of the composite dressing, the phenomenon of unstable structure of the composite dressing can be overcome, and the heat insulation performance of the composite dressing is improved.
The invention also provides a negative pressure drainage device, which comprises a composite dressing, a negative pressure sucker, a nano mesh and a drainage outlet pipe connected with a negative pressure absorber, wherein one end of the drainage outlet pipe is inserted into an outlet of the negative pressure sucker, a semi-permeable sealing film is attached to the surface of the composite dressing, the semi-permeable sealing film is in contact with the negative pressure sucker, and the nano mesh is attached to the composite dressing far away from the semi-permeable sealing film.
Furthermore, the drainage outlet pipe mouth is an L-shaped silica gel or polyethylene hose fitting.
Further, the negative pressure suction cup is an oval boss structure of 50mm x 40mm, a through hole has been seted up to negative pressure suction cup central authorities, the negative pressure suction cup bottom is equipped with 4 ~ 6 evenly distributed's recess, recess and through hole intercommunication, the size of recess is preferably 4mm x 3 mm.
Furthermore, the diameter of the through hole is 7-9 mm.
Further, the nano-mesh cloth comprises a medical nano-silver non-woven fabric.
Further, the semi-permeable sealing film is a pressure-sensitive adhesive film of polyurethane or polyethylene.
The composite dressing is produced by mode punching processing according to the requirements of the same wound surface, when the composite dressing contacts a wound surface, the medical nano-silver non-woven fabric is attached to the wound surface, so that silver ions are continuously released to perform antibiosis and promote wound healing, then a semi-permeable membrane which can cover the wound surface by about 2cm is selected for fixing and sealing, and then a drainage outlet pipe is connected with a negative pressure absorber or a negative pressure suction port on a hospital wall to generate continuous negative pressure suction to perform negative pressure absorption treatment.
Through communicating the through-hole in negative pressure sucking disc center with the recess, imbibition when being convenient for negative pressure to adsorb converges to the export, and the tissue metabolite that the surface of a wound produced is difficult for blockking up, convenient and fast. The negative pressure suction cup is a device for connecting the composite dressing, transferring negative pressure and leading wound exudate out of the composite dressing.
The semi-permeable sealing film has the function of sealing the composite dressing and the negative pressure sucker, so that the whole device forms a closed environment to generate negative pressure.
The negative pressure absorber can generate negative pressure of-10 to-30 kpa, the negative pressure of the contact surface of the composite dressing and the wound surface is 10 to 20kpa, the generation of the negative pressure can reduce the surface oxygen partial pressure of the wound surface, so that bacteria are not easy to grow under the condition of low oxygen, and the bacterial cell wall is damaged by the partial vacuum effect generated by the negative pressure, so that the bacteria die.
Compared with the prior art, the invention has the following beneficial effects:
1. the composite dressing prepared by the preparation method has the advantages of high biological safety, high elasticity, softness and excellent permeability, can promote wound healing, and can be produced in batches;
2. according to the preparation method of the composite dressing, the pullulan solution is added in the preparation process of the composite dressing, so that the phenomenon of unstable structure of the composite dressing can be overcome, and the heat-insulating property of the composite dressing is improved;
3. the negative pressure drainage device provided by the invention is low in cost and convenient to use, and can meet the requirements of different wound positions.
Drawings
FIG. 1 is a schematic structural view of a negative pressure drainage device according to the present invention;
fig. 2 is a schematic top view of the negative pressure drainage device of the present invention.
In the figure: 1. a drainage outlet pipe; 2. a negative pressure sucker; 3. a composite dressing; 4. a semi-permeable sealing film; 5. and (4) nano mesh cloth.
Detailed Description
The present invention will be described in further detail with reference to the accompanying drawings and examples.
In the following examples, the viscose, elastic polyester staple and low-melting polyester staple fibers referred to are commercially available, unless otherwise specified.
Example 1
S1, compounding a nano-silver-containing solution on viscose fibers and elastic polyester staple fibers, mixing the viscose fibers and the elastic polyester staple fibers according to a mass ratio of 1:1, putting the mixture into a cotton mixer, adding 10ml of pullulan solution with the mass concentration of 1g/ml, fully mixing for 30min, uniformly mixing, then putting the mixture into a double-cylinder carding machine for carding, controlling the carding speed to be 20m/min and the interval of cylinders to be 25mm, and then spreading and continuously lapping to form a fiber web;
s2, arranging low-melting polyester short fibers on the fiber web, enabling the low-melting polyester short fibers to enter a vertical cotton swing head, controlling the swing speed for 40 times/min, folding the fiber web into a vertical continuous superposed state to form a plurality of 3D vertical cotton units which are abutted in parallel, and controlling the 3D vertical cotton units to be 10 cm;
s3, heating the obtained 3D upright cotton unit in an oven for heating and forming, wherein the heating time is 20min, the baking temperature is 160 ℃, cutting to obtain a composite dressing, and performing water pressing treatment to obtain the composite dressing with the water content of 30% by mass;
s4, during the use, as shown in fig. 1 and 2, compound dressing 3 and the laminating of nanometer screen cloth 5, nanometer screen cloth 5 covers or fills at the wound surface, 3 surperficial subsides of compound dressing have semi-permeable sealing membrane 4, negative sucker 2 is placed to 3 central points of compound dressing, the semi-permeable sealing membrane 4 forms the closed system with the lower bottom surface disc contact of negative sucker 2, negative sucker 2 is 50mm 40 mm's circular boss structure, the size has been seted up to sucker central department and has been offered the size and be 7mm through-hole, the size that negative sucker 2 bottom was equipped with 4 evenly distributed is 4mm 3mm recesses, recess and through-hole intercommunication, the imbibition collects to the export when being convenient for negative pressure adsorb, negative pressure drainage device still includes drainage outlet pipe 1, drainage outlet pipe 1 one end inserts negative sucker 2 exports, the other end passes through the flexible coupling negative pressure absorber, produce and last negative.
Example 2
S1, compounding a nano-silver-containing solution on viscose fibers and elastic polyester staple fibers, mixing the viscose fibers and the elastic polyester staple fibers according to a mass ratio of 1:1.5, putting the mixture into a cotton mixer, adding 10ml of pullulan solution with the mass concentration of 1.5g/ml, fully mixing the solution for 30min, uniformly mixing the solution, putting the solution into a double-cylinder carding machine for carding, controlling the carding speed to be 25m/min and the interval between cylinders to be 30mm, and then spreading and continuously lapping to form a fiber web;
s2, arranging low-melting polyester short fibers on the fiber web, enabling the low-melting polyester short fibers to enter a vertical cotton swing head, controlling the swing speed for 40 times/min, folding the fiber web into a vertical continuous superposed state to form a plurality of 3D vertical cotton units which are abutted in parallel, and controlling the 3D vertical cotton units to be 10 cm;
s3, heating the obtained 3D upright cotton unit in an oven for 25min, wherein the baking temperature is 170 ℃, cutting to obtain a composite dressing, and performing pressurized water treatment to obtain the composite dressing with the water content of 35% by mass;
s4, during the use, as shown in fig. 1 and 2, compound dressing 3 and the laminating of nanometer screen cloth 5, nanometer screen cloth 5 covers or fills at the wound surface, 3 surperficial subsides of compound dressing have semi-permeable sealing membrane 4, negative sucker 2 is placed to 3 central points of compound dressing, the semi-permeable sealing membrane 4 forms the closed system with the lower bottom surface disc contact of negative sucker 2, negative sucker 2 is 50mm 40 mm's circular boss structure, the size has been seted up to sucker central department and has been offered the size and be 7mm through-hole, the size that the negative sucker 2 bottom was equipped with 5 evenly distributed is 4mm 3mm recesses, recess and through-hole intercommunication, the imbibition collects to the export when being convenient for negative pressure adsorb, negative pressure drainage device still includes drainage outlet pipe 1, drainage outlet pipe 1 one end inserts negative sucker 2 exports, the other end passes through the flexible coupling negative pressure absorber, produce and last.
Example 3
S1, compounding a nano-silver-containing solution on viscose fibers and elastic polyester staple fibers, mixing the viscose fibers and the elastic polyester staple fibers according to a mass ratio of 1:20, putting the mixture into a cotton mixing machine, adding 10ml of pullulan solution with the mass concentration of 2g/ml, fully mixing for 30min, uniformly mixing, then putting the mixture into a double-cylinder carding machine for carding, controlling the carding speed to be 25m/min and the interval of cylinders to be 30mm, and then spreading and continuously lapping to form a fiber web;
s2, arranging low-melting polyester short fibers on the fiber web, enabling the low-melting polyester short fibers to enter a vertical cotton swing head, controlling the swing speed for 40 times/min, folding the fiber web into a vertical continuous superposed state to form a plurality of 3D vertical cotton units which are abutted in parallel, and controlling the 3D vertical cotton units to be 10 cm;
s3, heating the obtained 3D upright cotton unit in an oven for molding, wherein the heating time is 35min, the baking temperature is 185 ℃, cutting to obtain a composite dressing, and performing pressurized water treatment to obtain the composite dressing with the water content of 40% by mass;
s4, during the use, as shown in fig. 1 and 2, compound dressing 3 and the laminating of nanometer screen cloth 5, nanometer screen cloth 5 covers or fills at the wound surface, 3 surperficial subsides of compound dressing have semi-permeable sealing membrane 4, negative sucker 2 is placed to 3 central points of compound dressing, the semi-permeable sealing membrane 4 forms the closed system with the lower bottom surface disc contact of negative sucker 2, negative sucker 2 is 50mm 40 mm's circular boss structure, the size has been seted up at the sucking sucker central point and has been offered 8mm through-hole, the size that the negative sucker 2 bottom was equipped with 5 evenly distributed is 4mm 3mm recesses, recess and through-hole intercommunication, imbibition when being convenient for negative pressure adsorb collects to the export, negative pressure drainage device still includes drainage outlet pipe 1, drainage outlet pipe 1 one end inserts negative sucker 2 exports, the other end passes through the flexible coupling negative pressure absorber, produce and last negative pressure.
Example 4
S1, compounding a nano-silver-containing solution on viscose fibers and elastic polyester staple fibers, mixing the viscose fibers and the elastic polyester staple fibers according to a mass ratio of 1:2.5, putting the mixture into a cotton mixer, adding 10ml of pullulan solution with the mass concentration of 3g/ml, fully mixing for 40min, uniformly mixing, then putting the mixture into a double-cylinder carding machine for carding, controlling the carding speed to be 30m/min and the interval of cylinders to be 30mm, and then spreading and continuously lapping to form a fiber web;
s2, arranging low-melting polyester short fibers on the fiber web, enabling the low-melting polyester short fibers to enter a vertical cotton swing head, controlling the swing speed for 40 times/min, folding the fiber web into a vertical continuous superposed state to form a plurality of 3D vertical cotton units which are abutted in parallel, and controlling the 3D vertical cotton units to be 10 cm;
s3, heating the obtained 3D upright cotton unit in an oven for 40min, baking at 200 ℃, cutting to obtain a composite dressing, and performing pressurized water treatment to obtain the composite dressing with the water content of 40% by mass;
s4, during the use, as shown in fig. 1 and 2, compound dressing 3 and the laminating of nanometer screen cloth 5, nanometer screen cloth 5 covers or fills at the wound surface, 3 surperficial subsides of compound dressing have semi-permeable sealing membrane 4, negative sucker 2 is placed to 3 central points of compound dressing, the semi-permeable sealing membrane 4 forms the closed system with the lower bottom surface disc contact of negative sucker 2, negative sucker 2 is 50mm 40 mm's circular boss structure, the size has been seted up to sucker central department and has been offered the size and be 8mm through-hole, the size that negative sucker 2 bottom was equipped with 6 evenly distributed is 4mm 3mm recess, recess and through-hole intercommunication, imbibition when being convenient for negative pressure adsorb collects to the export, negative pressure drainage device still includes drainage outlet pipe 1, drainage outlet pipe 1 one end inserts negative sucker 2 exports, the other end passes through the flexible coupling negative pressure absorber, produce and last negative pressure.
Example 5
S1, compounding a nano-silver-containing solution on viscose fibers and elastic polyester staple fibers, mixing the viscose fibers and the elastic polyester staple fibers according to a mass ratio of 1:1.7, putting the mixture into a cotton mixer, adding 10ml of pullulan solution with the mass concentration of 2.6g/ml, fully mixing for 40min, uniformly mixing, then putting the mixture into a double-cylinder carding machine for carding, controlling the carding speed to be 30m/min and the intervals of cylinders to be 30mm, and then spreading and continuously lapping to form a fiber web;
s2, arranging low-melting polyester short fibers on the fiber web, enabling the low-melting polyester short fibers to enter a vertical cotton swing head, controlling the swing speed for 40 times/min, folding the fiber web into a vertical continuous superposed state to form a plurality of 3D vertical cotton units which are abutted in parallel, and controlling the 3D vertical cotton units to be 10 cm;
s3, heating the obtained 3D upright cotton unit in an oven for molding, wherein the heating time is 35min, the baking temperature is 180 ℃, cutting to obtain a composite dressing, and performing pressurized water treatment to obtain the composite dressing with the water content of 40% by mass;
s4, during the use, as shown in fig. 1 and 2, compound dressing 3 and the laminating of nanometer screen cloth 5, nanometer screen cloth 5 covers or fills at the wound surface, 3 surperficial subsides of compound dressing have semi-permeable sealing membrane 4, negative sucker 2 is placed to 3 central points of compound dressing, the semi-permeable sealing membrane 4 forms the closed system with the lower bottom surface disc contact of negative sucker 2, negative sucker 2 is 50mm 40 mm's circular boss structure, the size has been seted up to sucker central department and has been offered the size and be 8mm through-hole, the size that negative sucker 2 bottom was equipped with 6 evenly distributed is 4mm 3mm recess, recess and through-hole intercommunication, imbibition when being convenient for negative pressure adsorb collects to the export, negative pressure drainage device still includes drainage outlet pipe 1, drainage outlet pipe 1 one end inserts negative sucker 2 exports, the other end passes through the flexible coupling negative pressure absorber, produce and last negative pressure.
Comparative example 1
As in example 5, the only difference is: in step S1, no pullulan solution was added, and the remaining parameters were the same as in example 5.
Comparative example 2
As in example 5, the only difference is: the mass concentration of the pullulan solution added in the step S1 is 0.5g/ml, and the rest parameters are the same as those in the example 5.
Comparative example 3
As in example 5, the only difference is: the mass concentration of the pullulan solution added in the step S1 is 10g/ml, and the rest parameters are the same as those in the example 5.
In the above examples and comparative examples, the drainage spout is an "L" shaped silicone or polyethylene hose, and in other embodiments the drainage spout may be of other shapes or made of other materials.
In the above examples and comparative examples, the nano mesh fabric is a medical nano silver non-woven fabric, and in other examples, other nano mesh fabrics may be used.
In the above examples and comparative examples, the semipermeable sealing film was a pressure-sensitive adhesive film of polyurethane or polyethylene.
Test example I, Performance test
1.1 Heat insulation Performance test
According to an ASTM D1518-2014 textile material heat transfer test method, the composite dressing prepared in the embodiments 1-5 and the comparative examples 1-3 is covered on a test board, the test board, a bottom board and a surrounding protection board are controlled to have the same temperature through electric heating, and are kept to have constant temperature in a power-on and power-off mode, so that the heat of the test board can be dissipated only in the direction of a sample, the heating time required for keeping the test board at constant temperature within a certain time is measured, the heat preservation rate of the sample is calculated, the test is carried out for 5 times, and the average value is obtained.
1.2 test of air permeability
According to the test method for testing the air permeability of the GB/T5453-1997 textile fabric, the air permeability is calculated by measuring the airflow which vertically passes through a given area of a sample in a certain time under the specified pressure difference condition. The air flow rate can be directly measured, or obtained by measuring the flow aperture and converting the pressure difference between the two surfaces, and the average value is obtained after 5 times of testing.
1.3 test of elastic recovery Properties
The elastic recovery performance test is carried out by referring to the test method of GB/T18941-2003 high polymer porous elastic material constant load impact fatigue, the sample is placed at the central part under the pressure head, the impact position is adjusted to be equivalent to the thickness of the sample, the relative position of the pressure head and the platform is adjusted, the specified load of (75 +/-20) N is applied, the elastic recovery is determined by the change of the thickness after the test is continued for a period of time, the test is carried out for 5 times, and the average value is taken.
The test results are shown in Table 1.
TABLE 1
| Group of | Rate of heat preservation | Air permeability (mm/s) | Elastic recovery rate |
| Example 1 | 88.1％ | 120.5 | 54.5％ |
| Example 2 | 87.5％ | 127.5 | 55.2％ |
| Example 3 | 89.5％ | 136.1 | 57.9％ |
| Example 4 | 91.0％ | 130.3 | 60.7％ |
| Example 5 | 95.6％ | 146.7 | 68.5％ |
| Comparative example 1 | 65.4％ | 115.1 | 51.4％ |
| Comparative example 2 | 85.7％ | 118.2 | 52.5％ |
| Comparative example 3 | 82.1％ | 116.7 | 53.9％ |
As can be seen from the data in table 2, the composite dressings prepared in examples 1 to 5 have the characteristics of high elasticity, good air permeability and high heat preservation rate, and the structure of the dressing is stable, the composite dressing prepared in comparative example 1 (without adding pullulan solution) has poor heat preservation performance, the stability of the composite dressing is not good, and the air permeability and the elastic recovery rate of the composite dressing are not much different from those of the composite dressings prepared in examples 1 to 5, which indicates that the pullulan has little influence on the air permeability and the elastic recovery rate. The mass concentration of the pullulan solution is adjusted in the comparative examples 2 and 3, the stability of the composite dressing is inferior to that of the composite dressings prepared in the examples 1-5, the heat preservation performance is poor, when the mass concentration of the pullulan solution is large, the air permeability of the composite dressing is reduced, and the fact that the mass concentration of the pullulan solution is within a certain range is proved that the air permeability of the composite dressing can be improved.
Test example two, test comparison
The composite dressings prepared in examples 1 to 5 and the existing PVA dressings were used as a control group for experimental comparison, and the specific results are shown in Table 2.
The blood perfusion amount of the wound surface and the wound cavity is the amount (ml) of blood which can flow into the wound surface or the wound cavity wall of each square centimeter per 100g of blood per minute; the larger the perfusion amount of the wound surface cavity blood flow is, the more active the generation of capillary vessels in a unit area is, and the faster the growth rate of granulation tissue is. PU ═ ml.100 g-1·min-1。
Bacteria count, which is the number of viable bacteria in a unit volume; the greater the bacterial count, the greater the likelihood of infection.
TABLE 2
According to the data in table 3, the composite dressing prepared in the embodiments 1 to 5 of the present invention has a good antibacterial effect, a good effect of promoting wound healing, a high biological safety performance, and a low possibility of blocking tissue metabolites, and the negative pressure drainage device composed of the composite dressing, the drainage outlet pipe, the negative pressure suction cup, the semi-permeable sealing film and the nano mesh fabric is convenient to use, simple in structure and low in cost.
The embodiments of the present invention are preferred embodiments of the present invention, and the scope of the present invention is not limited by these embodiments, so: all equivalent changes made according to the structure, shape and principle of the invention are covered by the protection scope of the invention.
Claims (10)
1. The preparation method of the composite dressing is characterized by comprising the following steps:
s1, compounding a nano-silver-containing solution on viscose fibers and elastic polyester staple fibers, mixing the viscose fibers and the elastic polyester staple fibers according to a mass ratio of 1: 1-2.5, and carding, unfolding and continuously lapping to form a fiber web;
s2, arranging low-melting polyester staple fibers on the fiber web, and folding the fiber web into an upright continuous superposed state through a cotton folding device to form a plurality of side-by-side 3D upright cotton units;
and S3, heating the obtained 3D upright cotton unit in a hot melting environment for 20-40 min at the baking temperature of 160-200 ℃, and cutting to obtain the composite dressing.
2. The method for preparing a composite dressing according to claim 1, wherein in the step S1, a pullulan solution is further added in the mixing process.
3. The preparation method of the composite dressing according to claim 1, wherein the mass concentration of the pullulan solution is 1-3 g/ml.
4. The preparation method of the composite dressing according to claim 1, wherein the composite dressing is obtained by pressurized water treatment and contains 30-40% of water by mass.
5. The utility model provides a negative pressure drainage device, its characterized in that, includes composite dressing, negative sucker, nanometer screen cloth and connects the drainage outlet pipe of negative pressure absorber, negative sucker export is inserted to drainage outlet pipe one end, composite dressing surface subsides have the semi-permeable seal membrane, semi-permeable seal membrane contact negative sucker, composite dressing keeps away from the semi-permeable seal membrane and pastes the nanometer screen cloth.
6. The negative pressure drainage device according to claim 5, wherein the drainage outlet tube mouth is an "L" shaped silicone or polyethylene hose.
7. The negative pressure drainage device according to claim 5, wherein the negative pressure suction cup is of a 50mm x 40mm oval boss structure, a through hole is formed in the center of the negative pressure suction cup, 4-6 uniformly distributed grooves are formed in the bottom of the negative pressure suction cup, and the grooves are communicated with the through hole.
8. The negative pressure drainage device according to claim 7, wherein the diameter of the through hole is 7-9 mm.
9. The negative pressure drainage device according to claim 5, wherein the nano-mesh cloth comprises a medical nano-silver non-woven fabric.
10. The negative pressure drainage device according to claim 5, wherein the semi-permeable sealing film is a pressure-sensitive adhesive film of polyurethane or polyethylene.
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