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CN111000592A - Tissue biopsy cutting device for bile duct stenosis diseases - Google Patents

Tissue biopsy cutting device for bile duct stenosis diseases Download PDF

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Publication number
CN111000592A
CN111000592A CN201910981247.9A CN201910981247A CN111000592A CN 111000592 A CN111000592 A CN 111000592A CN 201910981247 A CN201910981247 A CN 201910981247A CN 111000592 A CN111000592 A CN 111000592A
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China
Prior art keywords
cutting device
outer tube
biopsy
operating handle
rod
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Pending
Application number
CN201910981247.9A
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Chinese (zh)
Inventor
孟文勃
王煜栋
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First Hospital of Lanzhou University
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First Hospital of Lanzhou University
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Priority to CN201910981247.9A priority Critical patent/CN111000592A/en
Publication of CN111000592A publication Critical patent/CN111000592A/en
Pending legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
    • A61B10/02Instruments for taking cell samples or for biopsy
    • A61B10/0233Pointed or sharp biopsy instruments
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
    • A61B10/02Instruments for taking cell samples or for biopsy
    • A61B10/0233Pointed or sharp biopsy instruments
    • A61B10/0266Pointed or sharp biopsy instruments means for severing sample

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medical Informatics (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pathology (AREA)
  • Molecular Biology (AREA)
  • Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Surgical Instruments (AREA)

Abstract

The invention relates to the technical field of medical instruments, in particular to a tissue biopsy cutting device for bile duct stenosis diseases, which comprises an operating handle, a luer connector, an outer tube and a transmission wire, wherein the outer tube is hollow, one end of the outer tube is connected with the operating handle, and the transmission wire is arranged in the outer tube and the operating handle; the luer joint is arranged at one end of the side wall of the outer tube close to the operating handle; the biopsy cutting device further comprises a cutting device, the cutting device is hollow cylindrical, the cutting device is detachably arranged at the tail end of the transmission wire, and at least two barbs are arranged on the side wall of the cutting device. The barb of the invention can accurately position and cut pathological tissues, the cutting process is simple, the wound to the tissues is small, the sample storage amount of the metal tube is large, the sample is not lost in the taking process, the positive detection rate of the obtained sample is high, and the barb can be clinically popularized and applied.

Description

Tissue biopsy cutting device for bile duct stenosis diseases
Technical Field
The invention relates to the technical field of medical instruments, in particular to a tissue biopsy cutting device for bile duct stenosis diseases.
Background
Biliary stricture is a common clinical disease and is caused by benign stricture or malignant tumor, the benign biliary stricture is caused by injury of bile duct or inflammatory change of bile duct, or scar constriction of bile duct cavity caused after biliary tract operation, and the malignant biliary stricture is mainly caused by tumor compression. The judgment of benign and malignant properties of biliary stricture is very important for the selection of a treatment mode of a patient and the prognosis of a disease, but clinical differential diagnosis is very difficult, particularly malignant biliary stricture, the patient belongs to middle and late stages when obvious clinical manifestations appear due to atypical early symptoms, the radical surgical resection rate and survival rate are low, and the prognosis is very poor.
Endoscopic Retrograde Cholangiopancreatography (ERCP) is an important means for diagnosing and treating diseases of the pancreatic-biliary system. The ERCP can display the complete appearance of the bile ducts inside and outside the liver, but the sensitivity, specificity and accuracy of the qualitative diagnosis of the bile duct stenosis are not high enough; ultrasonic (IDUS) in the bile duct cavity under the duodenoscope can directly carry out ultrasonic in the bile duct, is closer to pathological tissues, still belongs to imaging diagnosis and cannot obtain pathological bases.
At present, the histopathological examination methods of bile duct stenosis diseases mainly include cell brushing examination under ERCP, bile drainage cytology examination, biopsy forceps examination and the like. Cytology samples can only be obtained by cell brushing examination and bile drainage cytology examination under ERCP, the positive rate is low (only 20-30%), the accuracy is poor, and the clinical diagnosis is greatly limited; the biopsy forceps inspection is a method for entering a focus of a human body through an endoscope, sampling pathological tissues and then judging the state of an illness through detecting the pathological tissues, and has high accuracy, but the biopsy forceps inspection has large wound on a patient, the sampling amount of samples is small, and the sample tissues are possibly lost in the taking process, so that larger wound is caused. Other methods such as the high cost of the oral son-mother choledochoscope, time-consuming operation, fragile and easily damaged choledochoscope body, great trauma of percutaneous transhepatic biliary biopsy, difficult operation, biliary hemorrhage and perforation, easy tumor dissemination and other risks, which cause the clinical application to be limited. In the existing clinical treatment process, a biopsy sampling device which is accurate in sampling position, large in sampling amount and small in wound of a patient does not exist all the time.
The utility model discloses "biopsy forceps with guide wire channel" (201620656702.X) discloses a biopsy forceps with guide wire channel, can high efficiency get rid of pancreas bile duct support and can get into pancreas bile duct pathological change department biopsy sample, and the inventor has carried out comprehensive research to this equipment, finds that it passes through the jaw sample of alligator profile, but because the biliary tract is longer, and each section narrow degree is inconsistent, this equipment still has following a great deal of problems: 1. in order to avoid great trauma and medical accidents of a patient in the biopsy sampling process, small operation force is required to be ensured, so that the alligator-shaped forceps heads cannot be fully contacted, the scraped tissue amount is insufficient, multiple sampling is required to meet the requirement, and the injury of the patient is actually aggravated; 2. in order to ensure enough tissue scraping amount, the crocodile-shaped forceps head and the bile duct are required to be inclined at a large angle to sample, but the inclination angle and the sampling force between the forceps head and the bile duct cannot be accurately judged and controlled, so that a patient is greatly injured in the sampling process, and the instrument even penetrates through the bile duct, so that the life safety of the patient is endangered.
In order to solve the technical problems, the invention discloses a tissue biopsy cutting device for bile duct stenosis diseases, which is accurate in sampling position, large in sampling amount and small in wound to a patient compared with biopsy forceps disclosed in the prior art.
Disclosure of Invention
A tissue biopsy cutting device for bile duct stenosis diseases comprises an operating handle, a Ruhr joint 6, an outer tube 7 and a transmission wire 9, wherein the operating handle consists of a core rod 1, a sliding block 2 and an auxiliary push rod 3, the core rod 1 is in a hollow rod shape, one end of the core rod is provided with internal threads, the other end of the core rod is provided with a handle ring, and the side wall of the core rod is provided with an opening; the push-assisted rod 3 is arranged inside the core rod 1, and the slide block 2 is nested on the core rod 1 and can slide relative to the core rod 1; one end of the boosting rod 3 is connected to the sliding block 2, and the other end of the boosting rod 3 is connected with the transmission wire 9; the outer tube 7 is hollow, one end of the outer tube is connected with the operating handle, and the transmission wire 9 is arranged in the outer tube 7 and the operating handle; the luer joint 6 is arranged at one end of the side wall of the outer tube 7 close to the operating handle; biopsy surely get device still including surely getting device 8, surely get device 8 be hollow circular cylinder, detachable sets up in the end of driving silk 9, surely get 8 lateral walls of device and be equipped with two at least barbs 10, 10 openings of barb and surely get the inside of device 8 and communicate with each other, be convenient for with surely get the sample tissue that obtains store in surely get 8 inside, prevent to lose sample tissue because of surely getting the removal of device 8, and the most advanced of barb 10 can hang sample tissue and prevent that the tissue from losing, carry out the secondary sampling and cause the injury to the patient.
Preferably, the cutting device 8 is made of metal, ceramic, rigid plastic or other material that can be used to achieve the present invention, and the barbs 10 are made of metal, alloy or other material that can be used to achieve the present invention, wherein the rigid, sharp material is more conducive to tissue sampling.
Preferably, the cutting device 8 and barbs 10 are made of metal steel.
Preferably, the direction of the barbs 10 can be the same as and/or opposite to the direction of pushing the cutting device 8, so that the biopsy tissue can be collected when the cutting device 8 is pushed or pulled, the operation times are reduced, the sampling amount is increased, and the harm to the patient is reduced.
Preferably, the cutting device 8 is provided with two barbs 10 in opposite directions to facilitate collection of the biopsy tissue.
Preferably, the included angle between the barb 10 and the wall of the cutting device 8 is 0-10 degrees, and the inclined angle is more favorable for the contact between the barb 10 and the wall of the bile duct so as to collect biopsy tissues from the wall of the bile duct.
Preferably, the included angle between the barbs 10 and the pipe wall of the cutting device 8 is 3-6 degrees.
Preferably, outer tube 7 on be equipped with the external screw thread, outer tube 7 and core bar 1 pass through threaded connection, outer tube 7 inside be equipped with two chambeies, be first chamber 12 and second chamber 13 respectively, drive wire 9 sets up in second chamber 13, promotes slider 2, drives and helps push rod 3 and drive wire 9 to slide in second chamber 13, core bar 1 on be equipped with the scale, medical personnel can adjust the position of slider 2 according to the scale.
Preferably, one end of the outer tube 7 close to the operating handle is provided with a protecting sleeve 5, and the protecting sleeve 5 is sleeved on the outer surface of the outer tube 7.
Preferably, the cross section of the outer tube 7 is circular, oval or any other shape that can realize the technical solution.
The invention has the beneficial effects that: medical personnel will surely get the device according to the appointed position of seal wire, when advancing appointed position, through constantly pushing and pulling slider 2, make 9 terminal surely get device 8 and the pathological tissue contact of transmission silk, surely get the barb 10 of 8 lateral walls of device and surely get pathological tissue, and constantly store the tissue of surely getting in the inside of surely getting device 8, lose pathological tissue when preventing taking out sampling device, and the most advanced of barb 10 can be hung the sample tissue and prevent that the tissue from losing, carry out the secondary sample and cause the injury to the patient. The invention can accurately position and cut pathological tissues, has simple cutting process, small wound to the tissues, large sample storage amount, no loss of samples in the taking process and high positive detection rate of the obtained samples, and can be clinically popularized and applied.
Drawings
FIG. 1 a front view of a biopsy incision device for biliary stricture diseases
1. A core bar; 2. a slider; 3. a push-aid rod; 5. sheathing a pipe; 6. a luer fitting; 7. an outer tube; 8. a cutting device; 9. a drive wire; 10. a barb; 12. a first chamber; 13. second chamber
FIG. 2 a cross-sectional view of a biopsy cutting device for biliary stricture diseases
Figure 3 different states of the barb 10
Cross section 1 of outer tube 7 in fig. 4
Cross section 2 of the outer tube 7 in fig. 5
Detailed Description
The technical solutions of the present invention are described below with reference to specific examples, but the technical solutions of the present invention are not limited to the following examples, and those skilled in the art can easily modify, replace or change the technical solutions without changing the spirit of the technical solutions of the present invention, and thus the technical solutions of the present invention are within the scope of protection.
Example 1 tissue biopsy incision device for biliary stenosis
A tissue biopsy cutting device for bile duct stenosis diseases comprises an operating handle, a luer connector 6, an outer tube 7 and a transmission wire 9, wherein the outer tube 7 is hollow, one end of the outer tube 7 is connected with the operating handle, and the transmission wire 9 is arranged in the outer tube 7 and the operating handle; the luer joint 6 is arranged at one end of the side wall of the outer tube 7 close to the operating handle; biopsy surely get device still including surely getting device 8, surely get device 8 be hollow circular cylinder, detachable sets up in the end of driving silk 9, surely get 8 lateral walls of device and be equipped with two opposite direction's barb 10, surely get device 8 and barb 10 and make by the metal steel. Be convenient for collect biopsy tissue, barb 10 be 5 with the contained angle of cutting 8 pipe walls of getting the device, the angle of slope more is favorable to the contact of barb 10 and courage pipe wall, collects biopsy tissue from the courage pipe wall. The operating handle consists of a core bar 1, a sliding block 2 and an auxiliary push rod 3, the core bar 1 is in a hollow rod shape, one end of the core bar is provided with internal threads, the other end of the core bar is provided with a handle ring, and the side wall of the core bar is provided with an opening; the push-assisted rod 3 is arranged inside the core rod 1, and the slide block 2 is nested on the core rod 1 and can slide relative to the core rod 1; one end of the boosting rod 3 is connected to the sliding block 2, and the other end of the boosting rod 3 is connected with the transmission wire 9; the outer tube 7 is provided with external threads, the outer tube 7 is in threaded connection with the core rod 1, two cavities are arranged inside the outer tube 7 and are respectively a first cavity 12 and a second cavity 13, the transmission wire 9 is arranged in the second cavity 13, the sliding block 2 is pushed to drive the push-aid rod 3 and the transmission wire 9 to slide in the second cavity 13, and the core rod 1 is provided with scales. One end of the outer tube 7 close to the operating handle is provided with a protecting tube 5, and the protecting tube 5 is sleeved on the outer surface of the outer tube 7. The cross section of the outer tube 7 is circular.
EXAMPLE 2 method of Using a biopsy excision device for biliary stenosis
(1) In the operation process, medical staff firstly put the guide wire into the biliary-pancreatic tract of a patient, then the guide wire is inserted along the first cavity 12 of the outer tube 7 and is penetrated out through the luer connector 6, and then the outer tube 7 enters along the guide wire and reaches the appointed position of the biliary-pancreatic tract;
(2) the slide block 2 is pushed, the transmission wire 9 connected with the slide block 2 is pushed out of the second cavity 13, and the cutting device 8 is exposed in the gallbladder-pancreas cavity;
(3) confirm the tissue that needs to be excised, promote slider 2 and make surely get device 8 and paste the tissue tightly, barb 10 is under the effect of thrust or pulling force, and the continuous tissue of cutting is stored in surely getting device 8, and after the sample was ended, take out biopsy and surely get the device and handle the sample of getting.

Claims (10)

1. A tissue biopsy cutting device for bile duct stenosis diseases comprises an operating handle, a luer connector (6), an outer tube (7) and a transmission wire (9), wherein the outer tube (7) is hollow, one end of the outer tube is connected with the operating handle, and the transmission wire (9) is arranged in the outer tube (7) and the operating handle; the luer connector (6) is arranged at one end of the side wall of the outer tube (7) close to the operating handle; the method is characterized in that:
the biopsy cutting device further comprises a cutting device (8), the cutting device (8) is in a hollow cylindrical shape and is arranged at the tail end of the transmission wire (9), and at least two barbs (10) are arranged on the side wall of the cutting device (8).
2. The biopsy extraction device of claim 1, wherein: the operating handle consists of a core bar (1), a sliding block (2) and a boosting rod (3), the core bar (1) is in a hollow rod shape, one end of the core bar is provided with internal threads, the other end of the core bar is provided with a handle ring, and the side wall of the core bar is provided with an opening; the push-aid rod (3) is arranged inside the core rod (1), and the sliding block (2) is nested on the core rod (1) and can slide relative to the core rod (1); one end of the push-aid rod (3) is connected to the sliding block (2), and the other end of the push-aid rod (3) is connected with a transmission wire (9); the outer pipe (7) is provided with external threads, and the outer pipe (7) is connected with the core rod (1) through threads.
3. The biopsy extraction device of claim 1, wherein: the cutting device (8) is detachably arranged at the tail end of the transmission wire (9).
4. The biopsy extraction device of claim 3, wherein: the cutting device (8) is made of metal, alloy, ceramic, rigid plastic or other materials capable of realizing the technical scheme, and the barbs (10) are made of metal, alloy materials or other materials capable of realizing the technical scheme.
5. The biopsy cutting device according to any one of claims 1-4, wherein: the direction of the barbs (10) can be the same as and/or opposite to the direction of pushing by the cutting device (8).
6. The biopsy extraction device of claim 5, wherein: the included angle between the barb (10) and the pipe wall of the cutting device (8) is 0-10 degrees.
7. The biopsy extraction device of claim 6, wherein: the included angle between the barb (10) and the pipe wall of the cutting device (8) is 3-6 degrees.
8. The biopsy cutting device according to claim 2, wherein the outer tube (7) has two cavities inside, a first cavity (12) and a second cavity (13), and the driving wire (9) is disposed in the second cavity (13) to push the slider (2) and drive the push-aid rod (3) and the driving wire (9) to slide in the second cavity (13).
9. The biopsy extraction device of claim 8, wherein: the cross section of the outer tube (7) is circular, oval or any other shape capable of realizing the technical scheme.
10. The biopsy extraction device of claim 8, wherein: one end of the outer tube (7) close to the operating handle is provided with a protective sleeve (5), and the protective sleeve (5) is sleeved on the outer tube (7).
CN201910981247.9A 2019-10-16 2019-10-16 Tissue biopsy cutting device for bile duct stenosis diseases Pending CN111000592A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201910981247.9A CN111000592A (en) 2019-10-16 2019-10-16 Tissue biopsy cutting device for bile duct stenosis diseases

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Application Number Priority Date Filing Date Title
CN201910981247.9A CN111000592A (en) 2019-10-16 2019-10-16 Tissue biopsy cutting device for bile duct stenosis diseases

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CN111000592A true CN111000592A (en) 2020-04-14

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113331881A (en) * 2021-06-07 2021-09-03 苏州法兰克曼医疗器械有限公司 Biopsy forceps capable of sampling continuously

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CN108271527A (en) * 2018-03-07 2018-07-13 宜春学院 A kind of envelop-type fruit picker
CN209004071U (en) * 2018-09-06 2019-06-21 北京爱琳医疗科技有限公司 A kind of puncture sampling instrument
CN111000593A (en) * 2019-10-16 2020-04-14 兰州大学第一医院 Tissue biopsy negative pressure cutting device for bile duct stenosis diseases
CN211749750U (en) * 2019-10-16 2020-10-27 兰州大学第一医院 Tissue biopsy cutting device for bile duct stenosis diseases
CN211749751U (en) * 2019-10-16 2020-10-27 兰州大学第一医院 Tissue biopsy negative pressure cutting device for bile duct stenosis diseases

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN201624008U (en) * 2010-01-05 2010-11-10 成都峻峰科技开发有限公司 High-altitude fruit picker
CN202222170U (en) * 2011-07-29 2012-05-23 李静菱 Retractable fruit picker
CN202960597U (en) * 2012-12-18 2013-06-05 南京微创医学科技有限公司 Biliary cytological brush
CN105377148A (en) * 2013-05-03 2016-03-02 费玛塞斯公司 Methods and devices for endometrial cell and tissue sampling
CN203555796U (en) * 2013-11-07 2014-04-23 王东 Sampling device under endoscope
CN103947377A (en) * 2014-05-12 2014-07-30 云南盛禾生态农业科技发展有限公司 Device for picking fruits from trees
CN204147061U (en) * 2014-11-12 2015-02-11 王俊英 End separate type Urology Department puncture needle
CN105557197A (en) * 2015-12-15 2016-05-11 桐城市神墩环卫保洁有限公司 Fruit picker
CN106073831A (en) * 2016-06-01 2016-11-09 南京法迈特科技发展有限公司 A kind of through scope aspiration biopsy, surface mucous movable detecting apparatus
CN206026366U (en) * 2016-06-29 2017-03-22 广州高志恒达科技有限公司 Subsidiary filament guiding channel's biopsy forceps
CN108271527A (en) * 2018-03-07 2018-07-13 宜春学院 A kind of envelop-type fruit picker
CN209004071U (en) * 2018-09-06 2019-06-21 北京爱琳医疗科技有限公司 A kind of puncture sampling instrument
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CN211749750U (en) * 2019-10-16 2020-10-27 兰州大学第一医院 Tissue biopsy cutting device for bile duct stenosis diseases
CN211749751U (en) * 2019-10-16 2020-10-27 兰州大学第一医院 Tissue biopsy negative pressure cutting device for bile duct stenosis diseases

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113331881A (en) * 2021-06-07 2021-09-03 苏州法兰克曼医疗器械有限公司 Biopsy forceps capable of sampling continuously
CN113331881B (en) * 2021-06-07 2022-09-02 苏州法兰克曼医疗器械有限公司 Biopsy forceps capable of sampling continuously

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