CN110934145B - Insecticidal composition containing acetamiprid and dimehypo - Google Patents
Insecticidal composition containing acetamiprid and dimehypo Download PDFInfo
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- CN110934145B CN110934145B CN201911105466.7A CN201911105466A CN110934145B CN 110934145 B CN110934145 B CN 110934145B CN 201911105466 A CN201911105466 A CN 201911105466A CN 110934145 B CN110934145 B CN 110934145B
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- Prior art keywords
- dimehypo
- acetamiprid
- insecticidal composition
- spodoptera frugiperda
- insecticidal
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- 239000000203 mixture Substances 0.000 title claims abstract description 37
- WCXDHFDTOYPNIE-RIYZIHGNSA-N (E)-acetamiprid Chemical compound N#C/N=C(\C)N(C)CC1=CC=C(Cl)N=C1 WCXDHFDTOYPNIE-RIYZIHGNSA-N 0.000 title claims abstract description 24
- 239000005875 Acetamiprid Substances 0.000 title claims abstract description 24
- 230000000749 insecticidal effect Effects 0.000 title claims abstract description 24
- QSOHVSNIQHGFJU-UHFFFAOYSA-L thiosultap disodium Chemical compound [Na+].[Na+].[O-]S(=O)(=O)SCC(N(C)C)CSS([O-])(=O)=O QSOHVSNIQHGFJU-UHFFFAOYSA-L 0.000 title claims abstract description 24
- 241000256251 Spodoptera frugiperda Species 0.000 claims abstract description 18
- 241000607479 Yersinia pestis Species 0.000 claims description 5
- 239000004480 active ingredient Substances 0.000 claims description 4
- 239000004562 water dispersible granule Substances 0.000 claims description 3
- 239000004563 wettable powder Substances 0.000 claims description 3
- 239000002270 dispersing agent Substances 0.000 claims description 2
- 239000002552 dosage form Substances 0.000 claims description 2
- 239000003995 emulsifying agent Substances 0.000 claims description 2
- 239000000945 filler Substances 0.000 claims description 2
- 239000003381 stabilizer Substances 0.000 claims description 2
- 239000000080 wetting agent Substances 0.000 claims description 2
- 239000002671 adjuvant Substances 0.000 claims 2
- 239000007884 disintegrant Substances 0.000 claims 1
- 230000000361 pesticidal effect Effects 0.000 claims 1
- 239000003814 drug Substances 0.000 abstract description 16
- 230000009286 beneficial effect Effects 0.000 abstract description 4
- 230000006378 damage Effects 0.000 abstract description 4
- 230000002195 synergetic effect Effects 0.000 abstract description 4
- 206010059866 Drug resistance Diseases 0.000 abstract description 3
- 235000013601 eggs Nutrition 0.000 description 10
- 239000003795 chemical substances by application Substances 0.000 description 8
- 230000001018 virulence Effects 0.000 description 8
- 240000008042 Zea mays Species 0.000 description 6
- 235000005824 Zea mays ssp. parviglumis Nutrition 0.000 description 6
- 235000002017 Zea mays subsp mays Nutrition 0.000 description 6
- 235000005822 corn Nutrition 0.000 description 6
- 230000000694 effects Effects 0.000 description 6
- 239000000575 pesticide Substances 0.000 description 6
- 238000000034 method Methods 0.000 description 5
- 230000003151 ovacidal effect Effects 0.000 description 5
- 239000007788 liquid Substances 0.000 description 4
- 230000001988 toxicity Effects 0.000 description 4
- 231100000419 toxicity Toxicity 0.000 description 4
- 235000013339 cereals Nutrition 0.000 description 3
- 238000002791 soaking Methods 0.000 description 3
- 238000010998 test method Methods 0.000 description 3
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 3
- 241000238631 Hexapoda Species 0.000 description 2
- 238000004166 bioassay Methods 0.000 description 2
- 229940079593 drug Drugs 0.000 description 2
- 238000001035 drying Methods 0.000 description 2
- 231100000194 ovacidal Toxicity 0.000 description 2
- 238000002360 preparation method Methods 0.000 description 2
- 230000002265 prevention Effects 0.000 description 2
- 239000000243 solution Substances 0.000 description 2
- 230000004083 survival effect Effects 0.000 description 2
- 244000105624 Arachis hypogaea Species 0.000 description 1
- 229920000742 Cotton Polymers 0.000 description 1
- 241000196324 Embryophyta Species 0.000 description 1
- 240000007594 Oryza sativa Species 0.000 description 1
- 235000007164 Oryza sativa Nutrition 0.000 description 1
- 241000209140 Triticum Species 0.000 description 1
- 235000021307 Triticum Nutrition 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- 230000000996 additive effect Effects 0.000 description 1
- 239000002390 adhesive tape Substances 0.000 description 1
- 230000008485 antagonism Effects 0.000 description 1
- 238000003556 assay Methods 0.000 description 1
- 239000012752 auxiliary agent Substances 0.000 description 1
- 238000004364 calculation method Methods 0.000 description 1
- 238000012272 crop production Methods 0.000 description 1
- 238000005520 cutting process Methods 0.000 description 1
- 230000007423 decrease Effects 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 238000010790 dilution Methods 0.000 description 1
- 239000012895 dilution Substances 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 230000000857 drug effect Effects 0.000 description 1
- 235000013399 edible fruits Nutrition 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 238000003912 environmental pollution Methods 0.000 description 1
- 239000002360 explosive Substances 0.000 description 1
- 238000009472 formulation Methods 0.000 description 1
- 230000012447 hatching Effects 0.000 description 1
- 235000003642 hunger Nutrition 0.000 description 1
- 238000007654 immersion Methods 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 230000002401 inhibitory effect Effects 0.000 description 1
- 230000005764 inhibitory process Effects 0.000 description 1
- 230000007246 mechanism Effects 0.000 description 1
- 230000001617 migratory effect Effects 0.000 description 1
- 238000002156 mixing Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 235000020232 peanut Nutrition 0.000 description 1
- 230000000149 penetrating effect Effects 0.000 description 1
- 239000004033 plastic Substances 0.000 description 1
- 230000000644 propagated effect Effects 0.000 description 1
- 235000009566 rice Nutrition 0.000 description 1
- 238000005070 sampling Methods 0.000 description 1
- 238000005507 spraying Methods 0.000 description 1
- 230000037351 starvation Effects 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 230000009044 synergistic interaction Effects 0.000 description 1
- 238000002723 toxicity assay Methods 0.000 description 1
- 235000013311 vegetables Nutrition 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
- A01N47/40—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having a double or triple bond to nitrogen, e.g. cyanates, cyanamides
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N41/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a sulfur atom bound to a hetero atom
- A01N41/02—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a sulfur atom bound to a hetero atom containing a sulfur-to-oxygen double bond
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Agronomy & Crop Science (AREA)
- Pest Control & Pesticides (AREA)
- Plant Pathology (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Dentistry (AREA)
- General Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Environmental Sciences (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
The invention provides an insecticidal composition containing acetamiprid and dimehypo, wherein the weight ratio of the acetamiprid to the dimehypo is 30: 1-1: 15, preferably 1: 1 and 1: 15. The composition has obvious synergistic effect, can reduce the use amount of medicaments, reduce the cost, reduce the harm to the environment and is beneficial to delaying the generation of the drug resistance of the insect spodoptera frugiperda.
Description
Technical Field
The invention belongs to the field of agricultural chemistry, and particularly relates to an insecticidal composition containing acetamiprid and dimehypo.
Background
Spodoptera frugiperda is a typical long-distance migratory flying pest and can be harmful to more than 80 plants such as grain crops (corn, rice, wheat and the like), economic crops (fruit trees, vegetables, flowers, cotton, peanuts and the like) and the like. Spodoptera frugiperda has become an important harm factor of local corn after 1 month in 2019 and invades the western region of Yunnan in China, and poses a threat to crop production in various provinces in southern China. The chemical pesticide has the characteristics of high efficiency, quick effect and convenient use, and is a main means for emergent prevention and control of explosive and sudden crop diseases and insect pests.
In addition, in order to overcome the defects of large dosage of a single pesticide, serious environmental pollution, high generation speed of germ resistance and the like, the invention provides an efficient and safe insecticidal composition containing acetamiprid and dimehypo. Under the optimal proportion, the composition has obvious synergistic effect, reduces the dosage of the medicament under the condition of ensuring the optimal control effect, reduces the cost, reduces the harm to the environment and is beneficial to delaying the generation of drug resistance.
The prior art does not report the combination use of the acetamiprid and the dimehypo.
Disclosure of Invention
In order to solve the problems in the prior art, the invention provides the following technical scheme:
an insecticidal composition containing acetamiprid and dimehypo is characterized in that active ingredients comprise the acetamiprid and the dimehypo, and the weight ratio of the acetamiprid to the dimehypo is 30: 1-1: 15.
The insecticidal composition is characterized in that the weight ratio of the acetamiprid to the dimehypo is 1: 1 and 1: 15.
The insecticidal composition is characterized by further comprising agriculturally acceptable auxiliaries, wherein the weight percentage of the active ingredients is 1-50%.
The insecticidal composition is characterized in that the auxiliary agent comprises a dispersing agent, an emulsifying agent, a disintegrating agent, a stabilizing agent, a wetting agent, a synergist, a penetrating agent and a filler.
The insecticidal composition is characterized in that: the dosage form which can be prepared by the composition is wettable powder and water dispersible granules.
The invention also relates to the use of the insecticidal composition according to the invention for controlling crop pests. Preferably spodoptera frugiperda.
Compared with the prior art, the invention has the following beneficial effects:
the insecticidal composition of the invention consists of two effective components with different action mechanisms, has obvious synergistic interaction after mixing, improves the control effect, and is beneficial to overcoming and delaying the generation of drug resistance of pests.
The composition of the invention is mixed with pesticide to reduce the dosage, thereby reducing the cost and lightening the pollution to the environment, having good safety and meeting the safety requirement of pesticide preparations.
The composition has excellent insecticidal and ovicidal effects on spodoptera frugiperda, and improves the control effect of the spodoptera frugiperda.
Detailed Description
The following detailed description of specific embodiments of the present invention is provided in conjunction with examples, but it should be understood that the scope of the present invention is not limited to the specific embodiments.
Indoor bioassay 1: indoor insecticidal toxicity determination method of acetamiprid and bisultap on spodoptera frugiperda
Test subjects: the Spodoptera frugiperda collected in the field is bred and propagated indoors by using corn leaves, and F1 generation egg masses and hatched 2-instar larvae bred by using corn leaves are used as experimental insect sources.
The test method comprises the following steps: the insecticidal activity of the medicament is determined by adopting a leaf soaking method. Preparing a series of drug solutions to be tested with concentration, cutting corn leaves into 5cm leaves, soaking the leaves in the drug solution for 10s, naturally drying the leaves, and placing the leaves in a circular plastic box. And selecting 2-instar larvae, performing starvation treatment for 4 hours, and inoculating the treated leaves. Clear water was used as control. Larvae were treated 20 at a time, 3 replicates. And checking the survival state of the larvae 48h after treatment, judging the larvae to die by no reaction when the brush lightly touches the body surface of the larvae, recording the death number and survival number, and calculating and correcting the death rate.
The treatment-corrected mortality was converted to a probability value, the concentration was converted to a logarithmic value, and the virulence equation and the inhibitory median concentration LC50 were calculated by the least squares method. Calculating the virulence index and the cotoxicity coefficient (CTC) of the medicament according to the Sun Yunpei method.
When the CTC is less than or equal to 80, the composition shows antagonism, when the CTC is more than 80 and less than 120, the composition shows additive action, and when the CTC is more than or equal to 120, the composition shows synergistic action.
Measured virulence index (ATI) ═ standard medicament LC 50/test medicament LC50 × 100
Theoretical virulence index (TTI) ═ A agent virulence index x percent of A in the mixture + B agent virulence index x percent of B in the mixture
Co-toxicity coefficient (CTC) × 100 [ measured toxicity index (ATI) of the mixture)/Theoretical Toxicity Index (TTI) of the mixture ].
The results of the virulence determination are shown in table 1 below.
TABLE 1 acetamiprid and dimehypo indoor insecticidal virulence determination for Spodoptera frugiperda
As shown in Table 1, the weight ratio of the acetamiprid to the dimehypo in the insecticidal composition is in the range of 1: 30-30: 1, the composition can be used for preventing and controlling Spodoptera frugiperda, and has excellent insecticidal activity. The preferred weight ratio of the acetamiprid to the dimehypo is 1: 1 and 1: 15.
Indoor bioassay 2: indoor ovicidal toxicity determination of acetamiprid and dimehypo against spodoptera frugiperda
The test method comprises the following steps: the ovicidal activity of the agent was determined by egg immersion. Selecting light green egg masses which are originally laid in the current day, dispersing the egg masses into single egg grains by using a brush, and uniformly adhering the egg grains on a transparent adhesive tape to prepare egg cards; soaking the egg card in the liquid medicine for 10s, sucking the excessive liquid medicine by using filter paper, drying the liquid medicine, and then putting the liquid medicine into a 50mL centrifuge tube. Clear water was used as control. Each 20 eggs were treated, 3 replicates. After the treatment 1d, the number of hatched and unhatched eggs was checked using a split dissecting microscope, and the hatching inhibition rate was calculated and corrected. The co-toxicity coefficient calculation method is the same as above.
TABLE 2 indoor ovicidal toxicity assay for acetamiprid and dimehypo against Spodoptera frugiperda
As shown in Table 2, the weight ratio of the acetamiprid to the dimehypo in the insecticidal composition is in the range of 1: 30-30: 1, the composition can be used for preventing and controlling Spodoptera frugiperda, and the weight ratio of the acetamiprid to the dimehypo is preferably in the range of 30: 1-1: 15.
It is found from tables 1 and 2 that when the weight ratio of the acetamiprid to the dimehypo is 1: 1 and 1: 15, the composition has excellent insecticidal and ovicidal effects on spodoptera frugiperda, and shows remarkable synergistic effects.
Determination of field drug Effect 1
Test subjects: spodoptera frugiperda (Spodoptera frugiperda) in corn field
The test method comprises the following steps: test set 2 medicament treatment, using clear water as a control, repeating the treatment for 3 times, setting a protection row with the area of each cell being 25m2, and randomly arranging and combining the cells. The medicine is applied in a stem and leaf spraying mode and is uniformly sprayed. And (3) respectively surveying the population density of each cell by adopting a five-point sampling method 1d before pesticide application and 7d after pesticide application, surveying 1m2 per point, recording the population number and damage condition of each point, and respectively calculating the population decline rate and the control effect.
Test agents:
agent 1: 8% acetamiprid-dimehypo wettable powder (1: 1)
Medicament 2: 16% acetamiprid-dimehypo water dispersible granule (1: 15)
TABLE 3 field control assay results for acetamiprid and dimehypo against Spodoptera frugiperda
| Treatment of | Dilution factor | Prevention effect/%) |
| Agent 1 | 1200 | 90.15 |
| Medicament 2 | 300 | 82.70 |
| Control | - | - |
Any modification, equivalent replacement, and improvement made within the spirit and principle of the present invention should be included in the protection scope of the present invention. All percentages in the formulation are by weight. The processing technology of each preparation of the composition is the prior art, and can be changed according to different conditions.
Claims (6)
1. An insecticidal composition containing acetamiprid and dimehypo is characterized in that active ingredients comprise the acetamiprid and the dimehypo, and the weight ratio of the acetamiprid to the dimehypo is 1: 1 and 1: 15.
2. An insecticidal composition according to claim 1 further comprising agriculturally acceptable adjuvants, the active ingredients being present in an amount of from 1 to 50% by weight.
3. An insecticidal composition according to claim 2 wherein said adjuvants include dispersants, emulsifiers, disintegrants, stabilisers, wetting agents, synergists, penetrants or fillers.
4. The insecticidal composition of claim 3, wherein: the dosage form which can be prepared by the composition is wettable powder and water dispersible granules.
5. Use of the pesticidal composition according to any one of claims 1 to 4 for controlling crop pests.
6. Use according to claim 5, characterized in that it is used for the control of Spodoptera frugiperda.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201911105466.7A CN110934145B (en) | 2019-11-12 | 2019-11-12 | Insecticidal composition containing acetamiprid and dimehypo |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201911105466.7A CN110934145B (en) | 2019-11-12 | 2019-11-12 | Insecticidal composition containing acetamiprid and dimehypo |
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| Publication Number | Publication Date |
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| CN110934145A CN110934145A (en) | 2020-03-31 |
| CN110934145B true CN110934145B (en) | 2021-10-29 |
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| CN201911105466.7A Active CN110934145B (en) | 2019-11-12 | 2019-11-12 | Insecticidal composition containing acetamiprid and dimehypo |
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Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN111802400A (en) * | 2020-08-05 | 2020-10-23 | 山东京博石油化工有限公司 | Acetamiprid and dimehypo-containing insecticidal effervescent tablet applied to paddy field by broadcasting and preparation method and application thereof |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1991004965A1 (en) * | 1989-10-06 | 1991-04-18 | Nippon Soda Co., Ltd. | Amine derivatives |
| CN1064587A (en) * | 1991-03-14 | 1992-09-23 | 希巴-盖吉股份公司 | Pesticidal combination |
| CN1159142A (en) * | 1994-07-28 | 1997-09-10 | 拜尔公司 | Pesticide |
| CN102972425A (en) * | 2012-12-26 | 2013-03-20 | 江苏省农业科学院 | Monosultap and acetamiprid compounded insecticide |
| JP2018070560A (en) * | 2016-11-04 | 2018-05-10 | 住友化学株式会社 | Soybean rust controlling method |
-
2019
- 2019-11-12 CN CN201911105466.7A patent/CN110934145B/en active Active
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1991004965A1 (en) * | 1989-10-06 | 1991-04-18 | Nippon Soda Co., Ltd. | Amine derivatives |
| CN1064587A (en) * | 1991-03-14 | 1992-09-23 | 希巴-盖吉股份公司 | Pesticidal combination |
| CN1159142A (en) * | 1994-07-28 | 1997-09-10 | 拜尔公司 | Pesticide |
| CN102972425A (en) * | 2012-12-26 | 2013-03-20 | 江苏省农业科学院 | Monosultap and acetamiprid compounded insecticide |
| JP2018070560A (en) * | 2016-11-04 | 2018-05-10 | 住友化学株式会社 | Soybean rust controlling method |
Non-Patent Citations (1)
| Title |
|---|
| 常用化学杀虫剂对草地贪夜蛾防效的室内测定;赵胜园 等;《植物保护》;20190415;第45卷(第3期);第10-14页 * |
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| CN110934145A (en) | 2020-03-31 |
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