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CN110903949A - Ventilation mechanism and biological fermentation device - Google Patents

Ventilation mechanism and biological fermentation device Download PDF

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Publication number
CN110903949A
CN110903949A CN201911400648.7A CN201911400648A CN110903949A CN 110903949 A CN110903949 A CN 110903949A CN 201911400648 A CN201911400648 A CN 201911400648A CN 110903949 A CN110903949 A CN 110903949A
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CN
China
Prior art keywords
air duct
bubble discharge
tube
vent
discharge section
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Pending
Application number
CN201911400648.7A
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Chinese (zh)
Inventor
陈曦
沈毅珺
吴劲松
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SHANGHAI FUDAN-ZHANGJIANG BIO-PHARMACEUTICAL CO LTD
Shanghai Fudan Zhangjiang Bio pharmaceutical Co Ltd
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SHANGHAI FUDAN-ZHANGJIANG BIO-PHARMACEUTICAL CO LTD
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Priority to CN201911400648.7A priority Critical patent/CN110903949A/en
Publication of CN110903949A publication Critical patent/CN110903949A/en
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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/06Nozzles; Sprayers; Spargers; Diffusers

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  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Sustainable Development (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)

Abstract

The invention discloses a ventilation mechanism and a biological fermentation device, which relate to the technical field of biological fermentation, wherein the ventilation mechanism comprises: an air duct; the air duct is provided with a bubble discharge section, and the side wall of the bubble discharge section of the air duct is provided with a plurality of first vent holes; the lower end of the air duct is provided with threads; the end opening of the lower end of the gas guide tube can be connected with the nut or the micro-bubble discharge tube through threads, a plurality of second vent holes are formed in the side wall of the micro-bubble discharge tube, and the aperture of each second vent hole is smaller than that of each first vent hole; the ventilation mechanism has at least two states, and in the first state, the port at the lower end of the air duct is connected with a nut through threads; in the second state, the port at the lower end of the air duct is connected with the micro-bubble discharge pipe through threads, and the first vent hole of the bubble discharge section is in a blocking state. This application can ventilate at the microbubble and switch between the atmospheric bubble is ventilated to can change the strategy of ventilating according to the demand of product.

Description

Ventilation mechanism and biological fermentation device
Technical Field
The invention relates to the technical field of biological fermentation, in particular to a ventilation mechanism and a biological fermentation device.
Background
Biological fermentation is an important component of bioengineering, and microorganisms utilize carbohydrate fermentation to produce various industrial solvents and chemical raw materials. Through research on the existing biological fermentation device, the problem that the yield and the quality of products are influenced along with the change of the products of the biological fermentation device is found, and the main reason is caused by an aeration mechanism in the biological fermentation device. In the actual use process, the aeration mechanism in the biological fermentation device has certain limitations, and the aeration strategy cannot be changed at will, so that the reaction process of the raw materials cannot be accurately controlled, and the finally obtained product is in the optimal quality and the optimal yield. Therefore, it is desirable to provide a new venting mechanism to solve the above problems.
Disclosure of Invention
In order to overcome the above-mentioned defects of the prior art, the technical problem to be solved by the embodiments of the present invention is to provide a ventilation mechanism and a biological fermentation device, which can switch between micro bubble ventilation and large bubble ventilation, so that the ventilation strategy can be changed according to the requirements of the product.
The specific technical scheme of the embodiment of the invention is as follows:
a vent mechanism, the vent mechanism comprising:
a gas-guide tube having a tendency to extend in a downward direction in a vertical direction; the air duct is provided with a bubble discharge section, the bubble discharge section is positioned at the lower end of the air duct, and the side wall of the bubble discharge section of the air duct is provided with a plurality of first vent holes; the port of the lower end of the air duct is provided with threads; the end opening of the lower end of the gas guide tube can be connected with the nut or the microbubble discharging tube through threads, a plurality of second vent holes are formed in the side wall of the microbubble discharging tube, and the aperture of each second vent hole is smaller than that of each first vent hole;
the ventilation mechanism has at least two states, and in the first state, the port at the lower end of the air duct is connected with the nut through threads; under the second state, the port department of the lower extreme of air duct is through threaded connection microbubble discharge pipe, the bubble discharge section first air vent is the shutoff state.
Preferably, the first vent holes are arranged in multiple rows, each row of the first vent holes is arranged along the extending direction of the bubble discharge section, and the multiple rows of the first vent holes are positioned on the left side wall or the right side wall of the air guide pipe.
Preferably, the aperture of first air vent is 200um, and each is arranged interval between the first air vent is 3mm, first air vent adopts laser drilling to process and forms.
Preferably, a sealing tube is sleeved on the bubble discharge section of the air guide tube, and the sealing tube and the air guide tube can slide; in a second state, the sealing tube covers the first vent hole of the air duct so as to enable the first vent hole to be in a blocking state.
Preferably, the sealing tube is a silicone tube.
Preferably, the inner wall of the lower end of the air duct is provided with an annular inner edge, and an O-shaped sealing ring is arranged between the tail part of the nut and the inner edge.
Preferably, a gasket is arranged between the head of the nut and the end face of the lower end of the gas guide tube, and the gasket is made of ultra-high molecular polyethylene.
Preferably, the air duct also has a horizontal section and an inclined section, the inclined section is located between the horizontal section and the bubble discharge section, and the height of the inclined section is reduced from the horizontal section to the bubble discharge section.
Preferably, a connecting mechanism is arranged on the horizontal section of the air duct, the connecting mechanism comprises a first connecting piece and a second connecting piece which can be connected with the first connecting piece, and the first connecting piece and the second connecting piece can rotate so as to change the angles of the inclined section and the air bubble discharge section.
A biological fermentation apparatus comprising an aeration mechanism as claimed in any one of the preceding claims.
The technical scheme of the invention has the following remarkable beneficial effects:
because the nut at the lower end of the air duct is detachably connected, the ventilation mechanism has at least two states. In the first state, the port at the lower end of the air duct is connected with the nut through threads. In the above state, relatively large bubbles can be discharged directly through the first vent hole of the bubble discharge section to meet the demand. Under the second state, the port department of the lower extreme of air duct is through threaded connection microbubble discharge pipe, the bubble discharge section first air vent is the shutoff state. In this state, the first vent hole of the air bubble discharge section is blocked, and the microbubble discharge tube is connected to the lower end of the airway tube, so that microbubbles are discharged directly through the second vent hole of the microbubble discharge tube to meet the requirement. Because the lower extreme and nut, the microbubble discharge pipe of air duct all are threaded connection, consequently, according to the needs of product, can switch at any time in order to change the strategy of ventilating.
Specific embodiments of the present invention are disclosed in detail with reference to the following description and drawings, indicating the manner in which the principles of the invention may be employed. It should be understood that the embodiments of the invention are not so limited in scope. The embodiments of the invention include many variations, modifications and equivalents within the spirit and scope of the appended claims. Features that are described and/or illustrated with respect to one embodiment may be used in the same way or in a similar way in one or more other embodiments, in combination with or instead of the features of the other embodiments.
Drawings
The drawings described herein are for illustration purposes only and are not intended to limit the scope of the present disclosure in any way. In addition, the shapes, the proportional sizes, and the like of the respective members in the drawings are merely schematic for facilitating the understanding of the present invention, and do not specifically limit the shapes, the proportional sizes, and the like of the respective members of the present invention. Those skilled in the art, having the benefit of the teachings of this invention, may choose from the various possible shapes and proportional sizes to implement the invention as a matter of case.
FIG. 1 is a left side view of a venting mechanism in an embodiment of the present application;
FIG. 2 is a front view of a venting mechanism in an embodiment of the present application;
FIG. 3 is a front view of a bubble discharge section in an embodiment of the present application;
fig. 4 is a cross-sectional view at a-a in fig. 3.
Reference numerals of the above figures:
1. an air duct; 11. a bubble discharge section; 111. a first vent hole; 12. an inclined section; 13. a horizontal segment; 14. a connecting section; 2. a nut; 3. an O-shaped sealing ring; 4. a gasket; 5. and a connecting mechanism.
Detailed Description
The details of the present invention can be more clearly understood in conjunction with the accompanying drawings and the description of the embodiments of the present invention. However, the specific embodiments of the present invention described herein are for the purpose of illustration only and are not to be construed as limiting the invention in any way. Any possible variations based on the present invention may be conceived by the skilled person in the light of the teachings of the present invention, and these should be considered to fall within the scope of the present invention. It will be understood that when an element is referred to as being "disposed on" another element, it can be directly on the other element or intervening elements may also be present. When an element is referred to as being "connected" to another element, it can be directly connected to the other element or intervening elements may also be present. The terms "mounted," "connected," and "connected" are to be construed broadly and may include, for example, mechanical or electrical connections, communications between two elements, direct connections, indirect connections through intermediaries, and the like. The terms "vertical," "horizontal," "upper," "lower," "left," "right," and the like as used herein are for illustrative purposes only and do not denote a unique embodiment.
Unless defined otherwise, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this application belongs. The terminology used herein in the description of the present application is for the purpose of describing particular embodiments only and is not intended to be limiting of the application. As used herein, the term "and/or" includes any and all combinations of one or more of the associated listed items.
In order to be able to switch between micro-bubble ventilation and large-bubble ventilation, so that the ventilation strategy can be changed according to the needs of the product, a ventilation mechanism is proposed in the present application, fig. 1 is a left side view of the ventilation mechanism in the embodiment of the present application, and fig. 2 is a front view of the ventilation mechanism in the embodiment of the present application, as shown in fig. 1 and 2, the ventilation mechanism may include: the gas guide pipe 1 has a trend of extending in a downward direction in the vertical direction; the air duct 1 is provided with a bubble discharge section 11, the bubble discharge section 11 is positioned at the lower end of the air duct 1, and the side wall of the bubble discharge section 11 of the air duct 1 is provided with a plurality of first vent holes 111; the port of the lower end of the gas guide tube 1 is provided with threads; the end opening of the lower end of the gas guide tube 1 can be connected with the nut 2 or the microbubble discharging tube through threads, a plurality of second vent holes are formed in the side wall of the microbubble discharging tube, and the aperture of each second vent hole is smaller than that of the corresponding first vent hole 111; the ventilation mechanism has at least two states, and in the first state, the port at the lower end of the air duct 1 is connected with the nut 2 through threads; in the second state, the port of the lower end of the airway tube 1 is connected with the microbubble discharging tube through threads, and the first vent hole 111 of the bubble discharging section 11 is in a blocking state.
In order to better understand the venting mechanism of the present application, it will be further explained and illustrated below. As shown in fig. 1, the airway tube 1 of the airway device may comprise a plurality of segments, each segment being angled with respect to the adjacent segment to achieve the purpose of bending. The gas-guiding tube 1 has a tendency to extend downward in the vertical direction as a whole, so that the gas is transported downward and discharged, and substances mixed into the gas-guiding tube 1 at the lower part, such as cell residues, cannot move upward and only deposit on the lower end of the lower gas-guiding tube 1. This may later facilitate cleaning of the entrained material for discharge from the airway tube 1.
As shown in fig. 1 and 2, the airway tube 1 may have a connecting section 14, a horizontal section 13, an inclined section 12, and a bubble discharging section 11, which are connected together in sequence. The inclined section 12 is located between the horizontal section 13 and the bubble discharging section 11, and the height of the inclined section 12 is reduced from the horizontal section 13 toward the bubble discharging section 11. The main purpose of the inclined section 12 is to create a height difference between different sections of the airway tube 1 so that any substance mixed into the airway tube 1 is deposited in the bubble discharge section 11 and cannot move upwards. In the above-mentioned air duct 1, as shown in fig. 2, there is no portion inclined upward from left to right, which can effectively avoid the dead angle formed in the air duct 1, and once the substance mixed in the air duct 1 falls into the dead angle, it is not convenient to clean the dead angle. The connecting section 14 of the gas guide tube 1 is used for air inlet, and the air flows through the horizontal section 13 and the inclined section 12 and can be discharged from the bubble discharge section 11.
In a possible embodiment, as shown in fig. 2, the horizontal section 13 of the airway tube 1 is provided with a connecting mechanism 5, and the connecting mechanism 5 comprises a first connecting piece and a second connecting piece which can be connected with the first connecting piece. And a first connecting piece and a second connecting piece are respectively arranged at two opposite ends of the horizontal section 13 of the air duct 1. The first connecting piece and the second connecting piece can rotate to change the angles of the inclined section 12 and the bubble discharge section 11, so that the positions of the inclined section 12 and the bubble discharge section 11 of the air guide pipe 1 can be adjusted.
As shown in fig. 2, the bubble discharge section 11 is located at the lower end of the airway tube 1. The side wall of the bubble discharge section 11 of the air duct 1 is provided with a plurality of first vent holes 111. When the gas in the gas guide tube 1 flows to the bubble discharge section 11, bubbles with proper size are formed through the first vent holes 111 on the side wall to be discharged to the outside, thereby improving the ventilation environment inside the biological fermentation device.
Fig. 3 is a front view of the bubble discharging section in the embodiment of the present application, and fig. 4 is a cross-sectional view taken along a-a in fig. 3, as shown in fig. 3 and 4, the first ventilation holes 111 are arranged in multiple rows, each row of the first ventilation holes 111 is arranged along the extending direction of the bubble discharging section 11, and the multiple rows of the first ventilation holes 111 are located on the left side wall or the right side wall of the gas-guide tube 1. In one specific embodiment, the number of rows of the first ventilation holes 111 is five, and the included angle between each row is 30 degrees. The aperture of the first vent holes 111 is preferably 200um, and the distance between the first vent holes 111 on each row is 3 mm. Since the first vent hole 111 has a small diameter, the first vent hole 111 needs to be formed by laser drilling. In the biological fermentation device, the outside of the first vent holes 111 is provided with reactants, the first vent holes 111 can discharge single bubbles with proper sizes under the aperture, the bubbles are relatively large, carbon dioxide generated in the reactants can be effectively driven, meanwhile, the influence of shearing force formed by the bubbles on the reactants can be reduced under the condition of meeting the requirement of dissolved oxygen, and the phenomenon that the form of the reactants is influenced under the shearing action of the bubbles to generate a certain degree of change is avoided.
As shown in fig. 2, in order to seal the lower end of the airway tube 1, a port at the lower end of the airway tube 1 is threaded, for example, it may be an internal thread. In a possible embodiment, the lower port of the airway tube 1 can be screwed with the nut 2 for occlusion purposes. In this kind of embodiment, for dismantling the connection between nut 2 and the air duct 1, consequently, mix the back in the air duct 1 after the material, the material all only can deposit in bubble discharge section 11, and at this moment, only need to dismantle nut 2 and just can clear up convenient and fast to the material of deposit in bubble discharge section 11.
As shown in fig. 2, in order to ensure the sealing degree between the gas-guide tube 1 and the nut 2, the inner wall of the lower end of the gas-guide tube 1 may have an annular inner edge, and an O-ring 3 may be disposed between the tail of the nut 2 and the inner edge. When the nut 2 is screwed up through the screw thread, the tail part of the nut 2 can press the O-shaped sealing ring 3, so that the sealing degree can be effectively improved.
As shown in fig. 2, a spacer 4 may be provided between the head of the nut 2 and the end surface of the lower end of the gas guide tube 1 in order to prevent the nut 2 and the gas guide tube 1 from being loosened after a long time. Meanwhile, the gasket 4 may be made of ultra-high molecular polyethylene, so that the gasket 4 has the advantages of impact resistance, wear resistance, good self-lubricating property, excellent low-temperature property and the like. In addition, the gasket 4 made of the material can prevent the material of the gasket 4 from influencing reactants in the biological fermentation device, and has no toxicity.
Because the nut 2 and the air duct 1 are detachably connected, after the nut 2 is detached, the port of the lower end of the air duct 1 can be connected with the microbubble discharging pipe through threads. The other end of the microbubble discharging pipe is closed, a plurality of second vent holes are formed in the side wall of the microbubble discharging pipe, and the aperture of each second vent hole is smaller than that of the corresponding first vent hole 111. The second vent holes on the microbubble discharging tube are mainly used for forming microbubbles, and the size of the microbubbles formed by the second vent holes is far smaller than that of the bubbles formed by the first vent holes 111. The main effect of microbubble is that contact takes place with biological fermentation device's reactant after the microbubble discharges, because its bubble size is very little, its dissolution efficiency that can increase the oxygen in the gas in the bubble by a wide margin. Therefore, when the type of product to be produced by the biological fermentation device is changed, the aeration strategy in the biological fermentation device may need to be changed to meet the requirements of different reactant reactions. For example, aeration may be for the purpose of driving off carbon dioxide, or to increase the rate of dissolution of oxygen. Therefore, the aeration mechanism in the bio-fermentation apparatus needs to switch between discharging relatively large bubbles through the first aeration hole 111 of the bubble discharge section 11 and discharging microbubbles through the microbubble discharge tube.
As shown in figure 2, the lower end of the air duct 1 is detachably connected with the nut 2, so that the ventilation mechanism has at least two states. In the first state, the port at the lower end of the air duct 1 is connected with the nut 2 through threads. In the above state, relatively large bubbles can be discharged directly through the first vent holes 111 of the bubble discharge section 11 to meet the demand. In the second state, the port of the lower end of the airway tube 1 is connected with the microbubble discharging tube through threads, and the first vent hole 111 of the bubble discharging section 11 is in a blocking state. In this state, the first vent hole 111 of the bubble discharge section 11 is blocked, and the microbubble releasing tube is connected to the lower end of the airway tube 1, so that microbubbles are directly discharged through the second vent hole of the microbubble releasing tube to meet the requirement. Because the lower extreme and nut 2 of air duct 1, microbubble discharge pipe all are threaded connection, consequently, according to the needs of product, can switch at any time in order to change the strategy of ventilating.
In order to realize the plugging of the first vent hole 111 of the bubble discharge section 11 in the second state, a sealing tube is sleeved on the bubble discharge section 11 of the air guide tube 1, and the sealing tube and the air guide tube 1 can slide. In the second state, the sealing tube covers the first vent hole 111 of the airway tube 1, so that the first vent hole 111 is in a blocking state. When it is necessary to shift to the first state, it is only necessary to slide the sealing tube so as to open the first vent hole 111.
In order to ensure the sealing degree when the sealing tube covers the first ventilation hole 111 of the airway tube 1 in the second state, the sealing tube is preferably selected to be a silicone tube. The silicone tube has certain elasticity, and it can effectively tighten up to compress tightly the first air vent 111 of air duct 1, so improved the leakproofness between the two greatly.
In a preferred embodiment, the ventilation mechanism may further have a third state in which the microbubble discharge tube is screwed to a port at the lower end of the airway tube 1, and the sealing tube is slid to cover at least a part of the first ventilation hole 111 of the airway tube 1. Can make the aeration system can enough discharge the microbubble through above-mentioned mode, can discharge great bubble again, reach the purpose of driving carbon dioxide and increasing the dissolution efficiency of oxygen simultaneously. In addition, the amount or degree of opening of the first vent holes 111 can be controlled at will by the degree of sliding the sealing tube, thereby achieving the purpose of controlling the amount of discharged large bubbles.
There is also provided in the present application a biological fermentation apparatus comprising an aeration mechanism as described in any one of the above.
All articles and references disclosed, including patent applications and publications, are hereby incorporated by reference for all purposes. The term "consisting essentially of …" describing a combination shall include the identified element, ingredient, component or step as well as other elements, ingredients, components or steps that do not materially affect the basic novel characteristics of the combination. The use of the terms "comprising" or "including" to describe combinations of elements, components, or steps herein also contemplates embodiments that consist essentially of such elements, components, or steps. By using the term "may" herein, it is intended to indicate that any of the described attributes that "may" include are optional. A plurality of elements, components, parts or steps can be provided by a single integrated element, component, part or step. Alternatively, a single integrated element, component, part or step may be divided into separate plural elements, components, parts or steps. The disclosure of "a" or "an" to describe an element, ingredient, component or step is not intended to foreclose other elements, ingredients, components or steps.
The embodiments in the present specification are described in a progressive manner, each embodiment focuses on differences from other embodiments, and the same and similar parts among the embodiments are referred to each other. The above embodiments are merely illustrative of the technical ideas and features of the present invention, and the purpose thereof is to enable those skilled in the art to understand the contents of the present invention and implement the present invention, and not to limit the protection scope of the present invention. All equivalent changes and modifications made according to the spirit of the present invention should be covered within the protection scope of the present invention.

Claims (10)

1. A vent mechanism, comprising:
a gas-guide tube having a tendency to extend in a downward direction in a vertical direction; the air duct is provided with a bubble discharge section, the bubble discharge section is positioned at the lower end of the air duct, and the side wall of the bubble discharge section of the air duct is provided with a plurality of first vent holes; the port of the lower end of the air duct is provided with threads; the end opening of the lower end of the gas guide tube can be connected with the nut or the microbubble discharging tube through threads, a plurality of second vent holes are formed in the side wall of the microbubble discharging tube, and the aperture of each second vent hole is smaller than that of each first vent hole;
the ventilation mechanism has at least two states, and in the first state, the port at the lower end of the air duct is connected with the nut through threads; under the second state, the port department of the lower extreme of air duct is through threaded connection microbubble discharge pipe, the bubble discharge section first air vent is the shutoff state.
2. The ventilation mechanism according to claim 1, wherein the first ventilation holes are arranged in a plurality of rows, each row of the first ventilation holes is arranged along the extending direction of the bubble discharge section, and the plurality of rows of the first ventilation holes are positioned on the left side wall or the right side wall of the air guide tube.
3. The vent mechanism according to claim 1, wherein the first vent holes have a diameter of 200um, and the first vent holes in each row are spaced at a distance of 3mm, and the first vent holes are formed by laser drilling.
4. The ventilation mechanism according to claim 1, wherein a sealing tube is sleeved on the bubble discharge section of the air guide tube, and the sealing tube and the air guide tube can slide; in a second state, the sealing tube covers the first vent hole of the air duct so as to enable the first vent hole to be in a blocking state.
5. The venting mechanism of claim 4, wherein the sealing tube is a silicone tube.
6. The ventilation mechanism according to claim 1, wherein the inner wall of the lower end of the air duct has an annular inner edge, and an O-ring is disposed between the tail of the nut and the inner edge.
7. The ventilation mechanism according to claim 1, wherein a gasket is arranged between the head of the nut and the end face of the lower end of the gas-guide tube, and the gasket is made of ultra-high molecular polyethylene.
8. The venting mechanism of claim 1, wherein the airway tube further comprises a horizontal segment and an inclined segment, the inclined segment is located between the horizontal segment and the bubble discharge segment, and the height of the inclined segment decreases from the horizontal segment to the bubble discharge segment.
9. The ventilation mechanism according to claim 8, wherein the horizontal section of the air duct is provided with a connecting mechanism, the connecting mechanism comprises a first connecting piece and a second connecting piece which can be connected with the first connecting piece, and the first connecting piece and the second connecting piece can rotate so as to change the angles of the inclined section and the air bubble discharge section.
10. A biological fermentation device, characterized in that it comprises an aeration means according to any one of claims 1 to 9.
CN201911400648.7A 2019-12-30 2019-12-30 Ventilation mechanism and biological fermentation device Pending CN110903949A (en)

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CN201911400648.7A CN110903949A (en) 2019-12-30 2019-12-30 Ventilation mechanism and biological fermentation device

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Application Number Priority Date Filing Date Title
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Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108034575A (en) * 2018-01-25 2018-05-15 吉林冠界生物技术有限公司 Microvesicle air-breather and system
EP3378520A1 (en) * 2017-03-24 2018-09-26 Besmed Health Business Corp. Bubble continuous positive airway pressure device
CN209722178U (en) * 2019-03-27 2019-12-03 厦门鹭港兆康生物科技有限公司 A kind of air-distributing device and the non-static bioreactor comprising it
CN212051377U (en) * 2019-12-30 2020-12-01 上海复旦张江生物医药股份有限公司 Ventilation mechanism and biological fermentation device

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3378520A1 (en) * 2017-03-24 2018-09-26 Besmed Health Business Corp. Bubble continuous positive airway pressure device
CN108034575A (en) * 2018-01-25 2018-05-15 吉林冠界生物技术有限公司 Microvesicle air-breather and system
CN209722178U (en) * 2019-03-27 2019-12-03 厦门鹭港兆康生物科技有限公司 A kind of air-distributing device and the non-static bioreactor comprising it
CN212051377U (en) * 2019-12-30 2020-12-01 上海复旦张江生物医药股份有限公司 Ventilation mechanism and biological fermentation device

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