CN110846159A - Antibacterial and bacteriostatic soap composition and prepared soap - Google Patents
Antibacterial and bacteriostatic soap composition and prepared soap Download PDFInfo
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- CN110846159A CN110846159A CN201911190245.4A CN201911190245A CN110846159A CN 110846159 A CN110846159 A CN 110846159A CN 201911190245 A CN201911190245 A CN 201911190245A CN 110846159 A CN110846159 A CN 110846159A
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- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D9/00—Compositions of detergents based essentially on soap
- C11D9/04—Compositions of detergents based essentially on soap containing compounding ingredients other than soaps
- C11D9/22—Organic compounds, e.g. vitamins
- C11D9/38—Products in which the composition is not well defined
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- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
- C11D3/48—Medical, disinfecting agents, disinfecting, antibacterial, germicidal or antimicrobial compositions
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- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D9/00—Compositions of detergents based essentially on soap
- C11D9/02—Compositions of detergents based essentially on soap on alkali or ammonium soaps
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Abstract
The invention relates to an antibacterial and bacteriostatic soap composition and a prepared soap, wherein the composition is called a skin caring formula and is prepared from ginseng, adenophora stricta, ampelopsis japonica and lotus leaves according to the proportion of (3-10): (5-15): (5-15): (7-15) by weight ratio and purifying to obtain the composition. Compared with the prior art, in the four medicines of the skin-nourishing formula, the ginseng is rich in ginsenoside, and the ginsenoside has the effects of improving the immunity of a human body, promoting substance metabolism, resisting tumors and fatigue, entering heart and lung channels, greatly tonifying primordial qi, tonifying spleen and lung, promoting the production of body fluid, soothing the nerves, resisting aging and the like. The root of straight ladybell belongs to a yin-nourishing traditional Chinese medicine and has a certain antifungal effect. The ampelopsis japonica has the effects of clearing heat and removing toxicity, eliminating carbuncle and dissipating stagnation, promoting granulation and healing sore, and resisting bacteria and diminishing inflammation, and the lotus leaf mainly has the effects of clearing summer heat and eliminating dampness. The prepared soap has good antibacterial and bacteriostatic effects.
Description
Technical Field
The invention relates to a soap, in particular to an antibacterial and bacteriostatic soap composition and a prepared soap.
Background
The soap is generally prepared from beef tallow, coconut oil or other grease, a small amount of foaming agent, caustic soda and other raw materials, and a certain amount of bactericide is added. The preparation process of the soap is the same as that of the washing soap.
The prior soap has the functions of cleaning and decontaminating, and generally has the function of sterilization.
The Chinese herbal medicine soap is prepared by adding soap base into Chinese herbal medicine extract and adding perfume. The Chinese herbal medicine soap has small irritation to skin, mild performance, auxiliary curative effect on partial skin diseases and no obvious side effect.
At present, common soap mainly has antibacterial and bacteriostatic functions, but at present, the requirements of people on soap products are not limited to cleaning and bacteriostatic, but people want to have more skin-care efficacy performance while cleaning skin. At present, more solid soap type face cleaning products appear on the market, and some products have better cleaning capability, but have stronger alkalinity and large irritation to skin, so that the skin can generate tight feeling after washing; some products have good cleaning effect, are mild and non-irritant, but have single function; some products are added with chemical components which are not beneficial to human bodies, such as synthetic perfume, silicon, viscous agent, foaming agent, emulsifier and the like, and are easy to cause damage to the skin.
Disclosure of Invention
The invention aims to overcome the defects of the prior art and provide an antibacterial and bacteriostatic soap composition and a prepared soap.
The purpose of the invention can be realized by the following technical scheme:
the invention provides a soap composition with antibacterial and bacteriostatic effects, which is called a skin caring formula and is prepared from ginseng, adenophora stricta, ampelopsis japonica and lotus leaves according to the proportion of (3-10): (5-15): (5-15): (7-15) by weight ratio and purifying to obtain the composition.
The extraction method of the composition comprises the following steps: mixing the following components in percentage by mass (3-10): (5-15): (5-15): (7-15) decocting the ginseng, the adenophora stricta, the ampelopsis japonica and the lotus leaves with water for 2 times, adding 8-12 times of water by mass of the ginseng, the adenophora stricta, the ampelopsis japonica and the lotus leaves for the first time, decocting for 0.5-2 hours, adding 6-10 times of water by mass of the ginseng, the adenophora stricta, the ampelopsis japonica and the lotus leaves for the second time, decocting for 0.1-1 hour, filtering, combining the filtrates, and concentrating under normal pressure to obtain a water extraction concentrated solution for later use.
The water extraction concentrated solution is further subjected to purification treatment to obtain the soap composition, and the purification treatment method comprises the following steps: adding ethanol with the volume of 1-3 times of that of the water extraction concentrated solution, stirring while adding, standing for 10-15 hours, separating supernatant, concentrating under reduced pressure until no alcohol smell exists, and concentrating under reduced pressure at 50-80 ℃ to obtain the soap composition.
Ginseng radix is dried root and rhizome of Panax ginseng C.A.Mey.of Araliaceae, radix Adenophorae is dried root of Glehnia littoralis Fr.Schmidtex Miq.of Umbelliferae, radix Ampelopsis japonica is dried root tuber of Ampelopsis japonica of Vitaceae, and folium Nelumbinis is dried leaf of Nelumbonaceae.
In one embodiment of the present invention, the soap composition is a concentrated solution having a concentration of 0.5 to 2g crude drug/ml.
In one embodiment of the present invention, the soap composition is a powder obtained by spray-drying a concentrated solution.
The invention also provides soap prepared from the soap composition, wherein the soap base of the soap contains the soap composition.
In one embodiment of the present invention, the soap base contains the soap composition in a proportion of 0.5 to 3.0% by weight.
In one embodiment of the present invention, the soap base is a sodium salt composed of the following fatty acids with different carbon chains in parts by weight:
fatty acids | FAC (%) incenseSoap index |
Dodecanoic acid | 5-8 |
Myristic acid | 4-6 |
Hexadecanoic acid | 38-43 |
Octadecaenoic acid | 36-41 |
Stearic acid | 5-8 |
The physical and chemical indexes of the soap base are as follows: the content of fatty acid is more than or equal to 78 percent, the content of free acid (calculated by oleic acid) is less than or equal to 0.8 percent, the content of chloride (calculated by NaCl) is less than or equal to 0.7 percent, the content of ethanol insoluble substance is less than or equal to 2 percent, and the content of water and volatile substance is less than or equal to 14 percent; the fatty acid solidification point is 39-43 ℃.
The invention also provides a preparation method of the soap, and the antibacterial soap is prepared by adding the soap composition into a soap base.
In the invention, the main functions and effects of the ginseng, the adenophora stricta, the ampelopsis japonica and the lotus leaf are as follows:
ginseng radix is dried root and rhizome of Panax ginseng C.A.Mey. Collected in autumn, washed, dried in the sun or oven-dried to obtain the raw material.
Ginseng contains mainly saponin, saccharide, protein, polypeptide, amino acid, organic acid, vitamin, liposoluble component and other components, and ginsenoside belongs to tetracyclic triterpene compounds, which can be classified into three types according to the structure of aglycon part, i.e. protopanaxadiol type saponin, such as ginsenoside Ra1, Ra2, Rb1, Rb2, Rc and Rd; protopanaxatriol type saponins such as ginsenoside Re, Rg1, Rf, Rg2 and Rh 1; oleanolic acid, such as ginsenoside Ro.
Ginsenoside has effects in improving immunity, promoting metabolism, resisting tumor, relieving fatigue, and resisting aging. D-pantethine, D-2-vitamin E and their mixture in Ginseng radix extract can regulate central nervous system, and the Ginseng radix can excite M-receptor to make Ginseng radix have peripheral cholinergic effect. In addition, ginseng can improve the contractility and frequency of the heart, excite the heart, accelerate blood flow, promote metabolism in vivo, further adjust the nutritional status of the organism and slow down physical decline. Ginsenoside has exciting effect on pituitary adrenal cortex system, and can protect adrenal cortex from function attenuation under strong stimulation condition, and also has stimulating effect on lipid and sugar metabolism. The ginseng root, ginseng stem and leaf and ginseng fruit extracts have the protein, RNA and DNA updating rate on animal liver, kidney, myocardial cell and bone marrow cell.
The Adenophora stricta is dried root of Glehnia littoralis Fr Schmidtex Miq.
The radix adenophorae medicinal material mainly contains volatile oil, glucoside, coumarins and the like, and also contains starch, triterpenic acid, stigmasterol, phospholipid, amino acid and other components.
The coumarins comprise a plurality of coumarin compounds such as imperatorin, isoimperatorin, allo-imperatorin, anabolin, xanthotoxin and bergapten, polyacetylenes mainly comprise panaxynol, farcaline diol, (8E) heptadeca-1, 8-diene-4, 6-diene-3, l0, diol and the like, phenolic acids mainly comprise vanillic acid, salicylic acid, ferulic acid, caffeic acid, chlorogenic acid, syringin and vanillic acid 4-O- β -D-pyranoside, phenolic acids mainly comprise alkylated glycosides such as n-butyl alcohol α -D-fructofuranoside, sterols such as stigmasterol, stigmasterol 3-O- β -D-pyranoside, and fatty acids such as linolenic acid, adenosine, uridine and the like.
The stem and leaf of Adenophora stricta has effects of inhibiting decrease of cyclophosphamide peripheral blood leukocyte and thymus index, and enhancing phagocytic function of hypoimmunity reticuloendothelial system. The radix Adenophorae can increase T lymphocyte subgroup and corresponding lymphocyte number, and enhance cellular immunity. Experiments show that 600 mg/(kg. d) radix glehniae crude polysaccharide and 800 mg/(kg. d) radix glehniae crude polysaccharide have obvious promotion effects on delayed type hypersensitivity and spleen B cell generation.
The water extract of radix Adenophorae can enhance myocardial contraction at low concentration, and inhibit myocardial contraction with increased concentration. The intravenous injection for the anesthetized rabbits can cause the blood pressure to rise, the respiration to strengthen and the vagus nerve to be cut off, and the effect still exists. In addition, the radix glehniae has the functions of nourishing yin, promoting the production of body fluid and tonifying qi, and has obvious curative effects on tumor patients with blood depletion, yin deficiency, cough due to yin deficiency and the like in combination with radiotherapy and chemotherapy.
The radix Ampelopsis refers to dry root tuber of Ampelopsis japonica (lour.) Merr. et Burk.) Makino of Vitaceae.
The ampelopsis japonica contains phenolic acid, anthraquinone, flavone, saponin and volatile oil components.
Wherein the flavonoids include uridine (uridine, 1), adenosine (adenosin, 2), ferulic acid (ferulic acid, 3), protocatechuic acid (protocatechoate, 4), gallic acid (gallicacid, 5), emodin-8-0- β -D-glucopyranoside (emodin-8-0- β -D-glucopyranoside, 6), caffeic acid (caffeicid, 7), β -sitosterol (β -sitosterol, 8), 7 β -hydroxy- β -sitosterol (7 β -hydroxy- β -sitosterol, 9).
The ampelopsis japonica has the main effect of inhibiting bacteria, and the water infusion (1: 3) of the ampelopsis japonica has different degrees of inhibiting effects on dermatophytes such as trichophyton concentrically, ozocerite ringworm, epidermophyton abdominalis and epidermophyton rubrum in a test tube. The methanol extract of Ampelopsis japonica and momordin extracted and purified from Ampelopsis japonica have inhibitory effect on activin (AP-1) activity and tumor cell proliferation. The momordin has the strongest inhibitory activity on tumor cells.
Animal experiments show that 3 kinds of Ampelopsis japonica extracts (5, 10, 20g/kg) with different dosages have promotion effects on mouse peripheral blood lymphocyte ANAE positive rate, T cell proliferation capacity and macrophage phagocytic function, and the effects increase along with the increase of the dosages, and the dosage effects are in positive correlation. In addition, the ampelopsis japonica decoction has a certain excitation effect on mice and an obvious inhibition effect on hair follicles.
The folium Nelumbinis is dried leaf of Nelumbo nucifera Gaertn of Nymphaeaceae. The folium Nelumbinis mainly contains alkaloids, flavonoids, organic acids, volatile oils, etc. Wherein, the content of the flavonoid compounds: quercetin (Querce2tin), Isoquercitrin (Isoquercitrin), and nelumboside. Organic acid compounds: tartaric acid (Tartaric acid), citric acid (Citricacid), malic acid (Malicic acid) and oxalic acid (Oxalicacid), gluconic acid (Maltonic acid), succinic acid (Amberacid), gallic acid (Gallicacid), n-Octacosane (Octacosane), n-octadecanoic acid (Stearic acid), benzoic acid (Benzoinic acid), O-hydroxybenzoic acid (O2hydroxybenzoic acid), and the like.
The lotus leaf alkaloid and flavone have lipid regulating effect, and small dose of lotus leaf flavone has inhibition tendency on in vitro liver cell synthesis of cholesterol, and has effects of reducing blood fat and reducing weight. The lotus leaf capsule capable of reducing blood fat is used for clinical patients with hyperlipidemia, and the results show that the lotus leaf capsule has the effects of reducing TC, regulating the metabolic level of a human body, and eliminating in-vivo metabolic products so as to reduce blood fat. The lotus leaf granule can reduce TC and TG contents in experimental hyperlipemia of rabbits, and has inhibitory effect on lipid precipitation and atherosclerosis in animal tissues. The lotus leaf mixture, lotus leaf beverage (composed of Chinese medicines such as rhizoma atractylodis, polygonum multiflorum and lotus leaf) and the like can reduce the specific viscosity of whole blood and the hematocrit, thereby improving the thick and viscous state of blood and inhibiting the occurrence of fatty liver. The activity test of the ethanol extract of the lotus leaves on 7 common food spoilage bacteria and pathogenic bacteria shows that the ethanol extract has obvious bacteriostatic action, particularly has the most obvious effect of inhibiting microorganisms mainly propagating by asexual fission, such as escherichia coli, staphylococcus aureus, saccharomycetes and the like, and the minimum bacteriostatic concentration of most of test bacteria is less than or equal to 80 percent. The folium Nelumbinis alkaloid component has antiviral, antiinflammatory and antiallergic effects. The n-butanol soluble fraction of folium Nelumbinis methanol extractive solution can inhibit muscle contraction caused by 52 hydroxytryptamine.
In the present invention, the quantitative analysis method of the main components in the herb extracts refers to the prior art method.
Compared with the prior art, the four medicines of ginseng, adenophora stricta, ampelopsis japonica and lotus leaves form a skin caring formula, and the skin caring formula is added into the conventional soap base to prepare the soap containing the traditional Chinese medicine components. The root of straight ladybell belongs to a yin-nourishing traditional Chinese medicine and has a certain antifungal effect. The ampelopsis japonica has the effects of clearing heat and removing toxicity, eliminating carbuncle and dissipating stagnation, promoting granulation and healing sore, and resisting bacteria and diminishing inflammation, and the lotus leaf mainly has the effects of clearing summer heat and eliminating dampness. The skin-caring formula prepared from the four medicines has good antibacterial, bacteriostatic, anti-inflammatory and antioxidant effects.
Detailed Description
The present invention will be described in detail with reference to specific examples.
The soap base used in the following examples is a commercially available soap base. The content of fatty acid in the soap base is more than or equal to 78 percent, the content of free acid (calculated by oleic acid) is less than or equal to 0.8 percent, the content of chloride (calculated by NaCL) is less than or equal to 0.7 percent, the content of ethanol insoluble substances is less than or equal to 2 percent, and the content of water and volatile substances is less than or equal to 14 percent; the fatty acid solidification point is 39-43 ℃.
Example 1
A soap composition with antibacterial and bacteriostatic effects is called a skin caring formula and is prepared from ginseng, adenophora stricta, ampelopsis japonica and lotus leaves according to the weight ratio of 6: 10: 10:10 by weight ratio and purifying the obtained composition.
Mixing the following components in percentage by mass 6: 10: 10:10, decocting the ginseng, the adenophora stricta, the ampelopsis japonica and the lotus leaves in water for 2 times, adding 8 times of water by mass of the ginseng, the adenophora stricta, the ampelopsis japonica and the lotus leaves for the first time, decocting for 1 hour, adding 8 times of water by mass of the ginseng, the adenophora stricta, the ampelopsis japonica and the lotus leaves for the second time, decocting for 0.5 hour, filtering, combining filtrates, and concentrating under normal pressure to obtain a water extraction concentrated solution for later use. The water extraction concentrated solution is further subjected to purification treatment to obtain the soap composition, and the purification treatment method comprises the following steps: adding 2 times volume of ethanol into the concentrated water extract, stirring, standing for 12 hr, separating supernatant, concentrating under reduced pressure until no alcohol smell is produced, and concentrating under reduced pressure at 60 deg.C to obtain the soap composition, i.e. concentrated solution with concentration of 1g crude drug/ml. And spray drying the concentrated solution to obtain medicinal powder.
This example also provides a soap prepared from the soap composition, wherein the soap base of the soap contains the soap composition in an amount of 2.0% by weight.
Example 2
A soap composition with antibacterial and bacteriostatic effects is called a skin caring formula and is prepared from ginseng, adenophora stricta, ampelopsis japonica and lotus leaves according to the weight ratio of 3: 5: 5: 7 by weight ratio and purifying the obtained composition.
Mixing the following components in a mass ratio of 3: 5: 5: 7 decocting the ginseng, the adenophora stricta, the ampelopsis japonica and the lotus leaves in water for 2 times, adding 8 times of water by mass of the ginseng, the adenophora stricta, the ampelopsis japonica and the lotus leaves for the first time, decocting for 0.5 hour, adding 6 times of water by mass of the ginseng, the adenophora stricta, the ampelopsis japonica and the lotus leaves for the second time, decocting for 0.1 hour, filtering, combining the filtrates, and concentrating under normal pressure to obtain a water extraction concentrated solution for later use. The water extraction concentrated solution is further subjected to purification treatment to obtain the soap composition, and the purification treatment method comprises the following steps: adding 1 volume of ethanol into the concentrated water extract, stirring, standing for 10 hr, separating supernatant, concentrating under reduced pressure until no alcohol smell is produced, and concentrating under reduced pressure at 50 deg.C to obtain the soap composition, i.e. concentrated solution with concentration of 1g crude drug/ml. And spray drying the concentrated solution to obtain medicinal powder.
This example also provides a soap prepared from the soap composition, wherein the soap base of the soap contains 2% by weight of the soap composition.
Example 3
A soap composition with antibacterial and bacteriostatic effects is called a skin caring formula and is prepared from ginseng, adenophora stricta, ampelopsis japonica and lotus leaves according to the weight ratio of 10: 15: 15: 15 by weight ratio and purifying the obtained composition.
Mixing the following components in a mass ratio of 10: 15: 15: 15 decocting the ginseng, the adenophora stricta, the ampelopsis japonica and the lotus leaves in water for 2 times, adding 12 times of water by mass of the ginseng, the adenophora stricta, the ampelopsis japonica and the lotus leaves for 2 hours for the first time, adding 10 times of water by mass of the ginseng, the adenophora stricta, the ampelopsis japonica and the lotus leaves for the second time, decocting for 1 hour, filtering, combining the filtrates, and concentrating under normal pressure to obtain a water extraction concentrated solution for later use. The water extraction concentrated solution is further subjected to purification treatment to obtain the soap composition, and the purification treatment method comprises the following steps: adding 3 times volume of ethanol into the concentrated water extract, stirring, standing for 15 hr, separating supernatant, concentrating under reduced pressure until no alcohol smell is produced, and concentrating under reduced pressure at 80 deg.C to obtain the soap composition, i.e. concentrated solution with concentration of 1g crude drug/ml. And spray drying the concentrated solution to obtain medicinal powder.
This example also provides a soap prepared from the soap composition, wherein the soap base of the soap contains 2% by weight of the soap composition.
Example 4
A soap composition with antibacterial and bacteriostatic effects is called a skin caring formula and is prepared by extracting and purifying ginseng, radix adenophorae, radix ampelopsis and lotus leaves according to a weight ratio of 9:12:10: 10.
Decocting ginseng, radix adenophorae, radix ampelopsis and lotus leaves in a mass ratio of 9:12:10:10 in water for 2 times, adding water in an amount which is 12 times that of the sum of the ginseng, the radix adenophorae, the radix ampelopsis and the lotus leaves for the first time, decocting for 2 hours, adding water in an amount which is 10 times that of the sum of the ginseng, the radix adenophorae, the radix ampelopsis and the lotus leaves for the second time, decocting for 1 hour, filtering, combining filtrates, and concentrating under normal pressure to obtain a water extraction concentrated solution for later use. The water extraction concentrated solution is further subjected to purification treatment to obtain the soap composition, and the purification treatment method comprises the following steps: adding 3 times volume of ethanol into the concentrated water extract, stirring, standing for 15 hr, separating supernatant, concentrating under reduced pressure until no alcohol smell is produced, and concentrating under reduced pressure at 80 deg.C to obtain the soap composition, i.e. concentrated solution with concentration of 1g crude drug/ml. And spray drying the concentrated solution to obtain medicinal powder.
This example also provides a soap prepared from the soap composition, wherein the soap base of the soap contains 2% by weight of the soap composition.
Comparative example 1
Unlike example 1, in this example, a composition was obtained by extracting and purifying only ginseng, and the composition was prepared into a soap. The soap base contains 2% of the composition by weight.
Comparative example 2
Unlike example 1, in this example, a composition was obtained by extracting only adenophora stricta and purifying the extract, and the composition was prepared into a soap. The soap base contains 2% of the composition by weight.
Comparative example 3
Unlike example 1, in this example, a composition was obtained by extracting and purifying only ampelopsis japonica, and the composition was prepared into a soap. The soap base contains 2% of the composition by weight.
Comparative example 4
Unlike example 1, in this example, a composition was obtained by extracting only lotus leaves and purifying, and the composition was prepared into a soap. The soap base contains 2% of the composition by weight.
Comparative example 5
Unlike example 1, in this example, a composition was obtained by extracting and purifying only ginseng and ampelopsis japonica, and the composition was prepared into a soap. The soap base contains 2% of the composition by weight.
Comparative example 6
Unlike example 1, in this example, a composition was obtained by extracting and purifying only adenophora stricta and lotus leaves, and the composition was prepared into a soap. The soap base contains 2% of the composition by weight.
In the above examples, the soap obtained in the comparative example is subjected to tests of antibacterial and bacteriostatic effects, and compared according to the tests of bacteriostatic performance of standard QB/T2738-2012, and specific detection data are shown in table 1.
It can be seen that the soap obtained in example 1 has the best antibacterial and bacteriostatic properties, and the tests of examples 2, 3 and 4 for antibacterial and bacteriostatic properties were performed in the same manner, wherein the antibacterial and bacteriostatic rates of example 2 were 83% and 84%, respectively, the antibacterial and bacteriostatic rates of example 3 were 86% and 82%, respectively, and the antibacterial and bacteriostatic rates of example 4 were 85% and 86%, respectively.
The embodiments described above are described to facilitate an understanding and use of the invention by those skilled in the art. It will be readily apparent to those skilled in the art that various modifications to these embodiments may be made, and the generic principles described herein may be applied to other embodiments without the use of the inventive faculty. Therefore, the present invention is not limited to the above embodiments, and those skilled in the art should make improvements and modifications within the scope of the present invention based on the disclosure of the present invention.
Claims (9)
1. A soap composition with antibacterial and bacteriostatic effects is characterized by being called a skin-caring formula and prepared from ginseng, adenophora stricta, ampelopsis japonica and lotus leaves according to the proportion of (3-10): (5-15): (5-15): (7-15) by weight ratio and purifying to obtain the composition.
2. The composition for soap having antibacterial and bacteriostatic effects according to claim 1, wherein the composition is extracted by a method comprising: mixing the following components in percentage by mass (3-10): (5-15): (5-15): (7-15) decocting the ginseng, the adenophora stricta, the ampelopsis japonica and the lotus leaves with water for 2 times, adding 8-12 times of water by mass of the ginseng, the adenophora stricta, the ampelopsis japonica and the lotus leaves for the first time, decocting for 0.5-2 hours, adding 6-10 times of water by mass of the ginseng, the adenophora stricta, the ampelopsis japonica and the lotus leaves for the second time, decocting for 0.1-1 hour, filtering, combining the filtrates, and concentrating under normal pressure to obtain a water extraction concentrated solution for later use.
3. The soap composition with antibacterial and bacteriostatic effects according to claim 2, wherein the water extract concentrate is further subjected to purification treatment to obtain the soap composition, and the purification treatment method comprises the following steps: adding ethanol with the volume of 1-3 times of that of the water extraction concentrated solution, stirring while adding, standing for 10-15 hours, separating supernatant, concentrating under reduced pressure until no alcohol smell exists, and concentrating under reduced pressure at 50-80 ℃ to obtain the soap composition.
4. The soap composition having antibacterial and bacteriostatic effects according to claim 1, wherein the ginseng is dried root and rhizome of Panax ginseng C.A.Mey. belonging to Araliaceae, the Adenophora stricta Fr.Schmidtex Miq. belonging to Umbelliferae, the Ampelopsis japonica dried root tuber of Ampelopsis japonica (Ampelopsis japonica) Makino belonging to Vitaceae, and the Nelumbo nucifera Gaertn. belonging to Nymphaeaceae.
5. The soap composition having antibacterial and bacteriostatic effects according to claim 1, wherein the soap composition is a concentrated solution having a concentration of 0.5 to 2g crude drug/ml.
6. The composition for soap having antibacterial and bacteriostatic effects according to claim 1, wherein the composition for soap is a powder obtained by spray-drying a concentrated solution.
7. A soap prepared from the composition for soap of any one of claims 1 to 6, wherein the soap base of the soap contains the composition for soap.
8. The soap of claim 7, wherein said soap base comprises said soap composition in a proportion of 0.5 to 3.0% by weight.
9. The soap of claim 7, wherein the physicochemical indices of the soap base are: the content of fatty acid is more than or equal to 78 percent, the content of free acid (calculated by oleic acid) is less than or equal to 0.8 percent, the content of chloride (calculated by NaCl) is less than or equal to 0.7 percent, the content of ethanol insoluble substance is less than or equal to 2 percent, and the content of water and volatile substance is less than or equal to 14 percent; the fatty acid solidification point is 39-43 ℃.
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CN116650583A (en) * | 2023-06-14 | 2023-08-29 | 哈尔滨田美药业股份有限公司 | Solid antibacterial gel and preparation method and application thereof |
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2019
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