CN110801268B

CN110801268B - Cancer embolus taking device

Info

Publication number: CN110801268B
Application number: CN201911095155.7A
Authority: CN
Inventors: 赵子粼
Original assignee: Guangzhou Huakeying Medical Technology Co ltd
Current assignee: Huakeying Medical Technology Guangzhou Co ltd
Priority date: 2019-11-11
Filing date: 2019-11-11
Publication date: 2021-05-25
Anticipated expiration: 2039-11-11
Also published as: CN110801268A

Abstract

The invention discloses a cancer embolus taking device which comprises an outer sheath tube; an inner sheath tube movably disposed within the outer sheath tube, and a moving unit movably disposed within the inner sheath tube; the thrombus taking device is arranged at the end part of the moving unit, which is positioned at the same side with the front end of the outer sheath tube; the embolectomy device is made of a memory material capable of generating deformation, so that the embolectomy device has an initial unfolding state of a basket-shaped structure corresponding to the embolectomy device when the embolectomy device is positioned outside the inner sheath tube and a contraction state corresponding to the embolectomy device when the embolectomy device is positioned inside the inner sheath tube, and the catcher is further arranged so that an opening of the basket-shaped structure faces the moving unit when the catcher is in the initial unfolding state and can sleeve the front end of the cancer embolus. When the thrombus taking device is positioned in the inner sheath tube, the outer diameter of the cancer thrombus taking device is smaller, so that the cancer thrombus is taken out by adopting a percutaneous transhepatic minimally invasive surgery instead of an operation and under the condition of positioning the cancer thrombus by B ultrasonic or X-ray.

Description

Cancer embolus taking device

Technical Field

The invention relates to the technical field of medical instruments, in particular to a cancer embolus taking device.

Background

The cancer embolus is one of the common complications of tumor patients, affects the life cycle and the life quality of the tumor patients, and can endanger the life of the tumor patients when the cancer embolus occurs in important tissues and organs of human bodies, so that the cancer embolus is taken out of the tumor patients, and is particularly important for delaying the progress of the disease conditions of the tumor patients and improving the survival rate and the life quality of the tumor patients. The existing thrombus taking method generally takes out a cancer thrombus from the body of a tumor patient by means of a cancer thrombus taking forceps under the condition of operation, for example, the cancer thrombus taking forceps with the notice number of CN208447718U and the medical bent type liver cancer portal vein cancer thrombus taking forceps with the notice number of CN206534679U both disclose a cancer thrombus taking forceps, and before taking out the thrombus, the operation of operation on the cancer thrombus patient is required to be carried out by the cancer thrombus taking forceps so that the cancer thrombus taking forceps can extend into the body of the tumor patient to take out the cancer thrombus. However, the use of forceps for removing the cancer embolus requires the use of the forceps in an operation, which is very harmful to the body of a patient with a tumor, and is not favorable for the recovery of the patient with the tumor.

Disclosure of Invention

In order to solve the problem that the cancer embolus removing forceps are used under the condition that a tumor patient is subjected to operation, so that the tumor patient is slow to recover, the invention provides a cancer embolus removing device.

The cancer embolus taking device comprises an outer sheath tube which is communicated with two ends and can be placed in a portal vein; the two ends of the inner sheath pipe are communicated and movably sleeved in the outer sheath pipe, and the length of the inner sheath pipe is greater than that of the outer sheath pipe; the moving unit is movably sleeved in the inner sheath tube, and the length of the moving unit is greater than that of the inner sheath tube; the thrombus taking device is arranged at the end part of the mobile unit and used for catching the cancer thrombus and is arranged at the end part of the mobile unit which is positioned at the same side with the front end of the sheath tube; the embolectomy device is characterized in that the embolectomy device is made of a memory material capable of generating deformation, the moving unit is arranged to drive the embolectomy device to reciprocate relative to the inner sheath tube along the axial direction of the inner sheath tube, so that when the embolectomy device moves from the outside to the inside of the inner sheath tube, the embolectomy device is changed to a contracted state from an initial expanded state, the initial expanded state of the embolectomy device is arranged to be in a basket-shaped structure, an opening of the basket-shaped structure faces the moving unit, and the embolectomy device is also arranged to be capable of sleeving the front end of the cancer embolus when the moving unit drives the embolectomy device to move towards the cancer embolus when the moving unit is in the initial expanded state, namely the opening of the embolectomy device is larger than the outer diameter of the front end of the cancer embolus. The front end of the outer sheath tube internally containing the inner sheath tube, the moving unit and the embolectomy device can extend into a blood vessel with the cancer embolus of a tumor patient from a wound and move along the pipeline of the blood vessel until the front end of the outer sheath tube moves to the rear end of the cancer embolus so as to facilitate the movement of the inner sheath tube and the embolectomy device; then, the inner sheath tube with the embolectomy device accommodated therein is moved towards one side of the cancer embolus, so that the inner sheath tube drives the moving unit and the embolectomy device to pass through the cancer embolus together; then, the moving unit drives the embolectomy device to move towards the end part of the inner sheath tube, which is the same as the front end of the outer sheath tube, until the embolectomy device is completely moved out of the inner sheath tube, at the moment, the embolectomy device is converted from a contraction state to an initial expansion state until the embolectomy device is expanded until the diameter of the opening of the embolectomy device is larger than that of the front end of the cancer embolus, and the expanded embolectomy device is positioned at the front end of the cancer embolus, so that the embolectomy device can sleeve the front end of the cancer embolus when the moving unit drives the embolectomy device to move towards one side of the cancer embolus; then, keeping the outer sheath pipe still, moving the moving unit and the inner sheath pipe towards one side where the outer sheath pipe is located, when the embolectomy device passes through the cancer embolus, sheathing the cancer embolus by the basket-shaped embolectomy device, and then driving the cancer embolus to move together by the embolectomy device; when the embolectomy device moves to the position that the opening of the embolectomy device is contacted with the front end of the outer sheath tube and continues to move towards the side where the outer sheath tube is positioned, the embolectomy device begins to shrink and deform under the action of the outer sheath tube, so that the thrombus taking device can move into the outer sheath tube when the thrombus taking device moves towards the side of the outer sheath tube, and the mouth part of the thrombus taking device moves into the outer sheath tube firstly, the cancer embolus can be cut through the contact of the mouth part of the embolus taking device and the front end of the outer sheath tube, and the cancer embolus can be wrapped by the embolus taking device when the embolus taking device is contracted and deformed, and can drive the cancer embolus wrapped in the embolus taking device to enter the outer sheath tube together in the process that the embolus taking device moves into the outer sheath tube, at the moment, because the diameter of the outer sheath is larger than that of the inner sheath, the embolectomy device which is positioned inside the outer sheath and outside the inner sheath is in the second contraction state, and the size of the embolectomy device at the moment is between the initial expansion state and the contraction state. Therefore, on one hand, the problem that the cancer embolus cannot be taken out when the cancer embolus taking device is taken out due to the fact that the cancer embolus is moved out of the opening of the embolus taking device to the outside of the embolus taking device when the embolus taking device is subjected to shrinkage deformation can be avoided; on the other hand, the cancer embolus taking device can also avoid that the cancer embolus in the embolus taking device is moved out of the embolus taking device in the moving process of the embolus taking device because the embolus taking device is not positioned in the outer sheath tube when the cancer embolus taking device is taken out, and the complete removal of the cancer embolus cannot be ensured.

In some embodiments, the cancer embolectomy device further comprises a wire-frame type snare disposed on the end of the mobile unit at which the embolectomy device is disposed; the snare device is made of a memory material capable of generating deformation, the moving unit is arranged to drive the snare device to reciprocate relative to the inner sheath tube along the axial direction of the inner sheath tube, so that when the snare device moves from the outside to the inside of the inner sheath tube, the snare device is changed to a contraction state from an initial expansion state, and when the snare device is in the initial expansion state, the snare device can sleeve the front end of the cancer embolus when the moving unit drives the snare device to move towards the cancer embolus, namely the inner diameter of the snare device is larger than the outer diameter of the front end of the cancer embolus at the moment. Therefore, when the inner sheath tube drives the moving unit, the embolectomy device and the snare device which are contained in the inner sheath tube to penetrate through the cancer embolus together, and the moving unit drives the embolectomy device and the snare device to move towards one end which is far away from the outer sheath tube relative to the inner sheath tube until the embolectomy device and the snare device are completely moved out of the inner sheath tube, at the moment, the embolectomy device and the snare device are changed from a contracted state to an initial expanded state until the embolectomy device is expanded to the state that the diameter of an opening of the embolectomy device is larger than that of the front end of the cancer embolus, and the snare device is expanded to the state that the inner diameter of the snare device is larger; when the inner sheath is moved, the embolectomy device and the loop device are driven by the moving unit to move towards the outer sheath, the head of the cancer embolus is firstly sheathed by the loop device, and when the loop device moves to be in contact with the front end of the outer sheath and continues to move towards one side where the outer sheath is located, the cancer embolus is cut by the contact of the loop device and the front end of the outer sheath; with the inner sheath and the moving unit moving continuously, the ferrule device moves into the outer sheath and is positioned outside the inner sheath, and at the moment, the ferrule device is also in a second contraction state, and the size of the ferrule device is between the initial expansion state and the contraction state; then, the moving unit drives the embolectomy device to move while the inner sheath tube continues to move, when the embolectomy device passes through the cancer embolus, the basket-shaped embolectomy device sleeves the cancer embolus, and then the embolectomy device drives the cancer embolus to move together; when the embolectomy device moves to the position that the opening of the embolectomy device is contacted with the front end of the outer sheath tube and continues to move towards one side where the outer sheath tube is located, the embolectomy device starts to shrink and deform under the action of the outer sheath tube, so that when the embolectomy device continues to move towards one side where the outer sheath tube is located, the embolectomy device can move into the inner part of the outer sheath tube, and when the opening of the embolectomy device moves into the outer sheath tube, a cancer embolus does not need to be cut, the cancer embolus is separated from the tube wall of a patient, on which the cancer embolus is grown.

In some embodiments, two groups of inner sheath tubes are provided, the moving unit comprises a first driving rod and a second driving rod which are both long-strip-shaped, the first driving rod and the second driving rod can be movably sleeved inside one group of inner sheath tubes independently, and the length of the first driving rod and the length of the second driving rod are both greater than the length of the inner sheath tubes sleeved outside the first driving rod and the second driving rod; the front end of the first transmission rod and the front end of the outer sheath tube are located on the same side, and the ferrule device is arranged on the end of the second transmission rod and the front end of the outer sheath tube are located on the same side. Therefore, after the inner sheath tube passes through the cancer embolus, the embolectomy device can be driven by the first transmission rod to move out of the inner sheath tube from the end part of the inner sheath tube, which is on the same side with the front end of the outer sheath tube, and the snare device can be driven by the second transmission rod to move out of the inner sheath tube from the end part of the inner sheath tube, which is on the same side with the front end of the outer sheath tube, and the movement time of the first transmission rod and the second transmission rod can be the same or different; then, when the inner sheath tube moves towards one side of the outer sheath tube, the loop device is driven by the second transmission rod to move towards one side of the outer sheath tube until the loop device moves into the outer sheath tube, so that the cancer embolus is separated from the wall of the patient, on which the cancer embolus is grown, through the contact between the loop device and the outer sheath tube; then, the inner sheath tube sleeved outside the first transmission rod moves towards one side where the outer sheath tube is located, meanwhile, the first transmission rod drives the embolectomy device to move towards one side where the outer sheath tube is located, the cancer embolus separated from the tube wall is sleeved, and the cancer embolus is moved into the outer sheath tube together when the embolectomy device moves into the outer sheath tube; finally, the outer sheath containing the inner sheath, the embolectomy device, the snare device and the cancer embolus is removed out of the body of the patient together, and the cancer embolus is taken out. Because this cancer embolus device of getting gets when stretching into the patient in and taking out from the patient, interior sheath pipe, get the embolus ware and lasso ware all are located the inside of outer sheath pipe to guarantee that whole cancer embolus gets the external diameter of embolus device less, be applicable to the minimal access surgery, be convenient for patient's recovery with the wound that reduces the patient.

In some embodiments, the snare is hexagonal and one of the sharp corners of the hexagon is connected to the second drive link. Thereby, on one hand, the snare is convenient to restore the initial unfolding state when the inner sheath is removed; on the other hand, because the sharp corner of the hexagon is connected with the end part of the second transmission rod, when the hexagon ferrule device is driven by the second transmission rod to move towards the outer sheath tube to be contacted with the front end of the outer sheath tube, the front end of the outer sheath tube applies pressure to two adjacent edges of the ferrule device adjacent to the sharp corner connected to the second transmission rod, so that the shrinkage deformation of the ferrule device is realized by reducing the included angle between the two adjacent edges, and the ferrule device is in a second shrinkage state; the ferrule device can be conveniently moved into the inner sheath tube to recover the contraction state.

In some embodiments, the angle between the plane of the hexagon of the ferrule holder and the second drive rod is in the range of 135 ° ± 15 °. Thereby, the snare is convenient to be sleeved outside the cancer bolt from the head of the cancer bolt.

In some embodiments, the front end of the outer sheath is sleeved with a foil used for cutting the cancer plug from the wall of the tumor patient where the cancer plug is grown. Thereby facilitating the embolectomy device or snare to cut the wall of the canceration embolus tumor patient when the embolectomy device or snare is contacted with the metal sheet.

In some embodiments, the snare is made of a titanium-nickel alloy, and the embolectomy device is an umbrella-shaped basket woven from titanium-nickel wires. Therefore, the snare and the embolectomy device have shape memory function, so that the snare and the embolectomy device automatically recover the unfolding state when being removed from the inner sheath tube, and the excision and the extraction of the cancer embolus are assisted.

In some embodiments, the diameter of the deployed state of the embolectomy device and snare device ranges from 8mm to 20 mm. Thus, even if a cancer embolus grows in a blood vessel having a small diameter such as a portal vein, the cancer embolus can be positioned by means of B-ultrasonic or X-ray without being operated, and the cancer embolus in the portal vein can be removed by a minimally invasive surgery using the cancer embolus removing device.

In some embodiments, the inner side of the wire frame-type snare is provided with a cutting portion for cutting the cancer plug. After the ferrule device is contacted with the metal sheet, the cancer embolus can be separated from the tube wall through the combined action of the cutting part arranged on the ferrule device and the metal sheet, so that the cancer embolus can be smoothly cut off from the tube wall, and the residual quantity of the cancer embolus on the tube wall is reduced; and because the cutting part is arranged at the inner side of the snare, when the cutter moves outside the sheath tube, the vessel wall of a patient with a cancer embolus can not be damaged.

In some embodiments, the front end of the sheath is curved so that the sheath is "J" shaped. Thus, when the embolectomy device is moved into the sheath, the opening at the distal end of the sheath can be directed toward the cancer embolus so that the cancer embolus can enter the sheath.

Drawings

FIG. 1 is a schematic structural view of a cancer embolectomy device according to an embodiment of the present invention;

FIG. 2 is a schematic view of the cancer embolectomy device of FIG. 1 from another perspective;

FIG. 3 is a schematic cross-sectional view taken along A-A of the cancer embolectomy device of FIG. 2;

FIG. 4 is a schematic structural view of a cancer embolectomy device according to another embodiment of the present invention;

FIG. 5 is a schematic view of the cancer embolectomy device of FIG. 4 from another perspective;

FIG. 6 is a schematic cross-sectional view taken along line B-B of the cancer embolectomy device of FIG. 5;

FIG. 7 is a schematic structural view of a cancer embolectomy device according to yet another embodiment of the present invention;

FIG. 8 is a schematic structural view of the cancer embolectomy device of FIG. 7 from another perspective;

FIG. 9 is a schematic cross-sectional view of the cancer embolectomy device of FIG. 8, taken along line C-C;

FIG. 10 is an enlarged schematic view of the cancer embolectomy device of FIG. 8 at D;

FIG. 11 is a schematic view of the second drive link and the ferrule holder of FIG. 7;

FIG. 12 is a schematic view of a first step of the method of operating the cancer embolectomy device of FIG. 7;

FIG. 13 is a second state diagram of the method of operation of the cancer embolectomy device of FIG. 7;

FIG. 14 is a third stage schematic view of the method of operating the cancer embolectomy device of FIG. 7;

FIG. 15 is a fourth stage of the method of operation of the cancer embolectomy device of FIG. 7;

FIG. 16 is a schematic view of the fifth step of the method of operating the cancer embolectomy device of FIG. 7;

FIG. 17 is a schematic view of a sixth step of the method of operating the cancer embolectomy device of FIG. 7;

FIG. 18 is a seventh stage of the method of operating the cancer embolectomy device of FIG. 7;

FIG. 19 is a schematic view of the embolectomy device positioned within the inner sheath;

fig. 20 is a schematic view of the configuration of the snare device within the inner sheath.

Detailed Description

The present invention will be described in further detail with reference to the accompanying drawings.

Fig. 1 to 3 schematically show a cancer embolectomy device according to a first embodiment of the present invention.

As shown in fig. 1 to 5, the cancer embolus removing device comprises an outer sheath 20, an inner sheath 70, a moving unit 50 and an embolectomy device 30; the outer sheath 20 is integrally formed or processed with an accommodating cavity 23, two ends of the outer sheath 20 communicate the accommodating cavity 23 with the outside, one end of the outer sheath 20 is a front end 21, the other end is a rear end 22, the outer sheath 20 can be arranged inside a portal vein, specifically, the diameter of the outer sheath 20 is set to be smaller than the inner diameter of a conduit (such as a blood vessel) of a tumor patient, which is long with a cancer plug 60, specifically, the diameter can be set to be 8mm-20mm according to needs, the outer sheath 20 has certain strength and cannot deform, the outer sheath 20 can be made of plastic which has certain strength and is not easy to deform according to needs, for example, the outer sheath can be made of tpe (thermoplastic elastomer) materials; the inner sheath 70 is movably sleeved in the accommodating cavity 23 of the outer sheath (movable along direction E as shown in fig. 1), and can extend out of the outer sheath 20 from the front end 21 and/or the rear end 22 of the outer sheath 20, the length of the inner sheath 70 is greater than that of the outer sheath 20, a second accommodating cavity is integrally formed or machined on the inner sheath 70, the second accommodating cavity can be used for accommodating the embolectomy device 30, and the outer diameter of the inner sheath 70 is much smaller than the inner diameter of the outer sheath 20; the moving unit 50 is movably sleeved in the second accommodating cavity of the inner sheath 70 (as shown in fig. 1, the moving unit can move along the direction F), and can extend out of the inner sheath 70 from the front end and/or the rear end of the inner sheath 70, the length of the moving unit 50 is greater than that of the inner sheath 70, specifically, when the moving unit 50 has a control part capable of controlling the moving unit 50 to move relative to the inner sheath 70, the position of the control part on the moving unit 50 is set such that, when the control part is located outside the rear end of the inner sheath 70, one end of the moving unit 50 is located outside the front end of the inner sheath 70; the embolectomy device 30 is arranged at the end of the moving unit 50, the embolectomy device 30 is positioned at the same side of the end of the moving unit 50 and the front end 21 of the outer sheath 20, and the embolectomy device 30 can capture a cancer embolus 60; the moving unit 50 is configured to drive the embolectomy device 30 to reciprocate relative to the inner sheath tube 70 along the axial direction of the inner sheath tube 70, and the embolectomy device 30 is made of a memory material capable of generating deformation, so that when the embolectomy device 30 moves from the outside of the inner sheath tube 70 to the inside of the inner sheath tube 70, the embolectomy device 30 is changed from the initial expanded state to the contracted state, namely, when the embolectomy device 30 is positioned outside the inner sheath tube 70, the embolectomy device 30 is in an initial unfolding state, the initial unfolding state of the embolectomy device 30 is arranged in a basket-shaped structure, and the basket-like structure opening 301 is directed toward the moving unit 50, the bolt remover 30 is further provided, when the embolectomy device 30 is in the initial, deployed state, the inner diameter of the opening 301 of the embolectomy device 30 is larger than the outer diameter of the leading end of the cancer embolus 60, so that when the embolectomy device 30 is driven by the moving unit 50 to move towards the side where the cancer embolus 60 is located, the embolectomy device 30 can cover the front end of the cancer embolus 60; when the embolectomy device 30 is in the contracted state, the outer wall of the embolectomy device 30 abuts against the inner wall of the second accommodating cavity of the inner sheath 70, i.e., the embolectomy device 30 is kept in the contracted state under the pressure of the inner wall of the inner sheath 70. In addition, the cancer embolus taking device can also avoid the cancer embolus 60 metastasis caused by the fact that the cancer embolus 60 is broken by laser when the embolus is taken by adopting modes of suction, grinding and the like, and fragments of the cancer embolus 60 are transferred along with blood. Preferably, all the transitions of the embolectomy device 30 with the basket-shaped structure are circular arc transitions, so as to avoid damage to the tube wall 61 of the tumor patient when the embolectomy device 30 moves relative to the tube wall 61 where the cancer embolus 60 is grown. Preferably, the outer diameter of the embolectomy device 30 in the deployed state is slightly larger than the inner diameter of the outer sheath 20, so as to avoid the embolectomy device 30 located outside the inner sheath 70 from wobbling when located inside the inner sheath 20.

When the cancer embolus taking device is used, firstly, the cancer embolus 60 can be positioned by B ultrasonic or X ray, then, in the process of minimally invasive surgery, the front end 21 of the outer sheath tube 20 which internally contains the inner sheath tube 70, the moving unit 50 and the embolus taking device 30 is extended into a blood vessel of a tumor patient where the cancer embolus 60 is grown from a wound and moves along the pipeline of the blood vessel until the front end 21 of the outer sheath tube 20 moves to the rear end of the cancer embolus 60, so as to reduce the resistance of the movement of the inner sheath tube 70 and the embolus taking device 30 (as shown in figure 12); then, the inner sheath 70 with the embolectomy device 30 accommodated therein is moved towards the side of the cancer embolus 60, so that the inner sheath 70 drives the moving unit 50 and the embolectomy device 30 to pass through the cancer embolus 60 together, at this time, the embolectomy device 30 is accommodated in the inner sheath 70, the embolus taking device 30 is in a contracted state, the shape is small, the outer diameter of the inner sheath 70 is also small, the cancer embolus 60 is not damaged when the inner sheath 70 passes through the cancer embolus, and the cancer embolus 60 is separated from the tube wall 61 with the cancer embolus 60 (as shown in fig. 13); then, the moving unit 50 drives the embolectomy device 30 to move towards the same end of the inner sheath 70 as the front end 21 of the outer sheath 20 until the embolectomy device 30 is completely removed from the inner sheath 70, at this time, the embolectomy device 30 is changed from the contracted state to the initial expanded state until the embolectomy device 30 is expanded until the inner diameter of the opening 301 of the embolectomy device 30 is larger than the diameter of the front end of the cancer embolus 60, and the expanded embolectomy device 30 is located at the front end of the cancer embolus 60 (as shown in fig. 14), so that the embolectomy device 30 can cover the front end of the cancer embolus 60 when moving towards the side of the cancer embolus 60 under the driving of the moving unit 50; then, the outer sheath 20 is kept still, the moving unit 50 and the inner sheath 70 are moved together toward the side of the outer sheath 20, when the embolectomy device 30 passes through the cancer embolus 60, the basket-shaped embolectomy device 30 sleeves the cancer embolus 60, and then the cancer embolus 60 is moved together by the embolectomy device 30 (as shown in fig. 17); when the embolectomy device 30 moves to the side where the opening 301 of the embolectomy device is in contact with the front end 21 of the outer sheath 20 and continues to move towards the side where the outer sheath 20 is located, the embolectomy device 30 starts to contract and deform under the action of the outer sheath 20, so that when the embolectomy device 30 continues to move towards the side where the outer sheath 20 is located, the embolectomy device 30 can move into the inside of the outer sheath 20, and since the mouth of the embolectomy device 30 moves into the outer sheath 20 first, the cancer embolus 60 can be cut through the contact between the mouth of the embolectomy device 30 and the front end 21 of the outer sheath 20, and the embolectomy device 30 can wrap the cancer embolus 60 when the embolectomy device contracts and can drive the cancer embolus 60 wrapped in the embolectomy device 30 into the outer sheath 20 during the process that the embolectomy device 30 moves into the outer sheath 20, at this time, since the diameter of the outer sheath 20 is larger than the diameter of the inner sheath 70, the embolectomy device 30 located inside of the outer sheath 20 and outside of the inner sheath 70 is in a second contracted state, the size of the embolectomy device 30 at this time is between the initial deployed state and the contracted state; finally, the outer sheath 20, which contains the inner sheath 70, the embolectomy device 30, and the cancer embolus 60 inside, is removed from the patient's body, thereby completing the removal of the cancer embolus 60 (see fig. 18). When the outer sheath tube 20 is placed in and taken out, the inner sheath tube 70 is positioned in the accommodating cavity 23 of the outer sheath tube 20, the embolectomy device 30 is positioned in the second accommodating cavity of the inner sheath tube 70, the outer diameter of the whole cancer embolectomy device is small, embolectomy can be completed by the cancer embolectomy device in the process of minimally invasive surgery without opening a tumor patient, and the recovery of the tumor patient is facilitated because a wound formed on the tumor patient by the minimally invasive surgery is small; moreover, since the mouth of the embolectomy device 30 faces the moving unit 50, when the embolectomy device 30 is moved from the front end 21 of the outer sheath 20 into the accommodating cavity 23 of the outer sheath 20 under the driving of the moving unit 50, the mouth of the embolectomy device 30 is moved into the accommodating cavity 23 of the outer sheath 20 first, so that the problem that the cancer embolus 60 cannot be taken out when the cancer embolus 60 is taken out of the embolectomy device 30 from the opening 301 of the embolectomy device 30 when the embolectomy device 30 is deformed due to shrinkage can be avoided; meanwhile, when the cancer embolus taking device is taken out of the body of a tumor patient, the embolus taking device 30 is positioned in the accommodating cavity 23 of the sheath tube 20, so that the situation that the cancer embolus 60 in the embolus taking device 30 is moved out of the embolus taking device 30 in the moving process of the embolus taking device 30 because the embolus taking device 30 is not positioned in the sheath tube 20 when the cancer embolus taking device is taken out can be avoided, and the complete taking out of the cancer embolus 60 cannot be ensured.

Preferably, in order to reduce the risk of the cancer embolus being detached from the wall of the canula 70 when the canula 70 passes through the cancer embolus while maintaining the strength of the canula 70, the canula 70 is made of a material similar to that of the outer canula 20, or a material made of a relatively soft PVC material, and the outer diameter of the canula 70 is in the range of 2mm to 5 mm.

Further, in order to facilitate the removal of the embolectomy device 30 and the cancer embolectomy device 60 in the embolectomy device 30 from the distal end 21 of the outer sheath 20 into the accommodating chamber 23 of the outer sheath 20, as shown in fig. 1 and 2, the outer sheath 20 is substantially straight, and only the distal end 21 of the outer sheath 20 is bent to form the outer sheath 20 into a "J" shape. Thus, when the embolectomy device 30 is moved into the outer sheath 20, the opening of the distal end 21 of the outer sheath 20 can be directed toward the cancer embolus 60 so that the cancer embolus 60 can enter the inside of the outer sheath 20.

Fig. 4 to 20 schematically show a cancer embolectomy device according to a second embodiment of the present invention.

The cancer embolus removing device in the present embodiment is different from the first cancer embolus removing device in that: as shown in fig. 4 to 9, the cancer embolus removing device further comprises a snare device 40, the snare device 40 is of a wire frame type, the snare device 40 is provided on an end portion of the moving unit 50 where the embolus removing device 30 is provided, the moving unit 50 is provided so as to be able to drive the snare device 40 to reciprocate relative to the inner sheath 70 along an axial direction of the inner sheath 70, and the snare device 40 is made of a memory material capable of generating deformation, such that, upon movement of snare 40 from the exterior to the interior of inner sheath tube 70, snare 40 transitions from the initial deployed state to a collapsed state (as shown in figure 20), i.e., the snare 40 is outside the inner sheath 70, the snare 40 is in an initial deployed state, the snare 40 is also arranged, when the snare 40 is in the initial deployment state, the snare 40 can be capable of moving the moving unit 50 toward the side of the cancer plug 60, and the snare 40 can be capable of sheathing the front end of the cancer plug 60, that is, the inner diameter of the snare 40 is larger than the outer diameter of the front end of the cancer plug 60; when the snare 40 is in the contracted state, the outer wall of the snare 40 abuts against the inner wall of the second accommodation chamber of the inner sheath 70, that is, the snare 40 is kept in the contracted state by the pressure of the inner wall of the outer sheath 20. Thus, when the inner sheath 70 carries the moving unit 50, the embolectomy device 30 and the snare 40 accommodated therein together to pass through the cancer embolus 60, and the moving unit 50 carries the embolectomy device 30 and the snare 40 to move relative to the inner sheath 70 toward the end away from the outer sheath 20 until the embolectomy device 30 and the snare 40 are completely removed from the inner sheath 70, at which time the embolectomy device 30 and the snare 40 are shifted from the contracted state to the initial expanded state (in which the embolectomy device 30 located in the second accommodation chamber 71 of the inner sheath 70 is in the contracted state, as shown in fig. 19, the embolectomy device 30 is similar to an umbrella, and when the embolectomy device 30 is accommodated in the inner sheath 70, it is similar to an umbrella accommodated in the umbrella housing), until the embolectomy device 30 is expanded to have an inner diameter of its opening larger than the diameter of the front end of the cancer embolus 60, and the snare 40 is expanded to have an inner diameter larger than the diameter of the front end of the cancer embolus 60 (as shown in fig. 14); while moving the inner sheath 70, the moving unit 50 drives the embolectomy device 30 and the snare device 40 to move towards the outer sheath 20, the head of the cancer embolus 60 is firstly sheathed by the snare device 40, and when the snare device 40 moves to contact with the front end 21 of the outer sheath 20 and continues to move towards the side of the outer sheath 20, the cancer embolus 60 is cut by the contact of the snare device 40 and the front end 21 of the outer sheath 20 (as shown in fig. 15 and 16); with the inner sheath 70 and the moving unit 50 moving further, the snare 40 moves into the outer sheath 20 and is located outside the inner sheath 70, and at this time, the snare 40 is also in the second contracted state, and the size thereof is between the initial expanded state and the contracted state (i.e. the exterior of the snare 40 is between the exterior of the snare 40 shown in fig. 8 and the exterior of the snare 40 shown in fig. 20); then, the moving unit 50 drives the embolectomy device 30 to move while continuing to move the inner sheath 70, when the embolectomy device 30 passes through the cancer embolus 60, the basket-shaped embolectomy device 30 sleeves the cancer embolus 60, and then the embolectomy device 30 drives the cancer embolus 60 to move together (as shown in fig. 17); when the embolectomy device 30 moves to the position where the opening 301 of the embolectomy device is contacted with the front end 21 of the outer sheath 20 and continues to move towards the side where the outer sheath 20 is located, the embolectomy device 30 starts to shrink and deform under the action of the outer sheath 20, so that when the embolectomy device 30 continues to move towards the side where the outer sheath 20 is located, the embolectomy device 30 can move into the inner part of the outer sheath 20, and when the mouth part of the embolectomy device 30 moves into the outer sheath 20, the cancer embolus 60 does not need to be cut, the cancer embolus 60 is separated from the tube wall 61 of the patient where the cancer embolus 60 is grown, and because the embolectomy device 30 does not need to be cut when being deformed, the embolectomy device 30 is guaranteed to be uniformly deformed, so that the embolectomy device 30 can smoothly move the cancer embolus 60 wrapped in the embolus device 30 into the outer sheath 20 together. Preferably, the outer diameter of the snare 40 in the expanded state is slightly larger than the inner diameter of the outer sheath 20 to avoid shaking of the snare 40 located outside the inner sheath 70 when located inside the inner sheath 20.

In order to facilitate the cutting of the cancer embolus 60 from the tube wall 61 of the tumor patient with the cancer embolus 60, and reduce the problem that the cancer embolus 60 cannot be completely removed and the cancer embolus 60 remains because the embolus remover 30 tears the cancer embolus 60 from the tube wall 61 of the tumor patient with the cancer embolus 60, as shown in fig. 4 to 9, a cutting unit for cutting the cancer embolus 60 from the tube wall 61 of the tumor patient with the cancer embolus 60 is sleeved at the front end 21 of the outer sheath tube 20. The specific cutting unit is a metal sheet 24 sleeved on the outer diameter or the inner diameter of the front end 21 of the outer sheath tube 20, and the metal sheet 24 is fixedly connected to the front end 21 of the outer sheath tube 20; or the foil 24 is attached directly to the front end 21 of the sheath 20. Thereby facilitating the removal of the cancer embolus 60 from the wall 61 of the tumor patient with the cancer embolus 60 by the embolus remover 30 or snare 40 when in contact with the foil 24; moreover, the metal sheet 24 arranged at the front end 21 of the sheath tube 20 can also provide support for deformation of the embolectomy device 30 and the snare device 40 when the embolectomy device 30 and the snare device 40 are moved into the accommodating chamber 23 of the sheath tube 20, on the one hand, the embolectomy device 30 and the snare device 40 are conveniently and incidentally transformed to the second contracted state; on the other hand, the front end 21 of the sheath 20 can be prevented from being worn by friction with the embolectomy device 30 and the snare device 40. Specifically, the metal thin plate 24 is wound around the distal end 21 of the sheath tube 20.

Specifically, the memory material of the embolectomy device 30 and the snare device 40 is titanium-nickel alloy, so that the snare device 40 and the embolectomy device 30 have a shape memory function, so that the snare device 40 and the embolectomy device 30 automatically recover a deployed state when being removed from the inner sheath 70, thereby assisting in the excision and extraction of the cancer embolus 60. More specifically, as shown in fig. 4 to 9, the embolectomy device 30 is woven by using titanium-nickel wires to form a basket shape, i.e., an umbrella shape, and specifically includes longitudinal connecting wires 31 and transverse connecting wires 32 which are both titanium-nickel wires and are woven with each other. Preferably, at least three longitudinal connecting wires 31 are provided, and one end of each of the three longitudinal connecting wires 31 is connected to the moving unit 50, so that when the moving unit 50 drives the embolectomy device 30 to move into the accommodating cavity 23 of the outer sheath 20 or into the second accommodating cavity of the inner sheath 70, the front end 21 of the outer sheath 20 or the front end of the inner sheath 70 can be uniformly deformed by pressing the longitudinal connecting wires 31. Preferably, the transverse connecting lines 32 are fixedly connected with the longitudinal connecting lines 31. More preferably, as shown in fig. 4, 6, 7 and 9, the embolectomy device 30 is configured such that, when it is in the initial expanded state, the maximum diameter of the basket shape is not at the opening 301, i.e., the opening 301 of the embolectomy device 30 is slightly contracted, so that the embolectomy device 30 is contracted and deformed under the pressure of the outer sheath 20 or the inner sheath 70.

Preferably, the diameter of the embolectomy device 30 and snare device 40 in the expanded state ranges from 8mm to 20 mm. Thus, even if the cancer plug 60 grows in a blood vessel having a small diameter such as a portal vein, the cancer plug 60 can be positioned by B-ultrasonic or X-ray without being operated, and the cancer plug 60 in the portal vein can be removed by a minimally invasive surgery using the cancer plug removal device. Preferably, the embolectomy device 30 and the snare device 40 are configured to have a size of 8mm, 10mm, 12mm, 14mm, 16mm, 20mm, etc. to accommodate the different diameters of the vessel wall 61 of the patient, or may be configured to have other sizes as desired.

Further, as shown in fig. 10, the inside of the wire frame type snare 40 is provided with a cutting portion 401 for cutting the cancer plug 60. After the ferrule device 40 contacts the metal sheet 24, the cancer embolus 60 can be separated from the tube wall 61 through the combined action of the cutting part 401 arranged on the ferrule device 40 and the metal sheet 24, so that the cancer embolus 60 can be smoothly cut from the tube wall 61, and the residual quantity of the cancer embolus 60 on the tube wall 61 is reduced; and because the cutting portion 401 is provided inside the snare unit 40, the wall 61 of the patient, on which the cancer plug 60 is grown, is not damaged when the cutter moves outside the sheath tube 20. Preferably, as shown with continued reference to fig. 10, the cutting portion 401 is formed by braiding a wire 402 made of metal to spirally wind the wire frame-shaped snare 40, and since the wire is spirally braided on the surface of the wire frame-shaped snare 40, the friction force between the snare 40 and the patient's tubular wall 61 is increased, so as to more thoroughly cut the cancer plug 60 from the patient's tubular wall 61. More preferably, the metal wire braided on the snare unit 40 is made of a titanium-nickel alloy having a shape memory function, so that the cutting portion 401 is deformed together when the snare unit 40 is moved into the accommodating chamber 23 of the sheath tube 20, and the cutting portion 401 is prevented from falling off from the snare unit 40 due to the deformation of the snare unit 40. Specifically, in order to facilitate the cutting portion 401 to cut the root of the cancer plug 60, the cutting portion 401 is provided in a nail shape.

In some embodiments, the moving unit 50 is an elongated rod, the rod is movably sleeved in the inner sheath 70, and the length of the rod is longer than that of the inner sheath 70, the snare device 40 and the embolectomy device 30 are fixedly connected to the end of the rod on the same side as the front end of the inner sheath 70, and the embolectomy device 30 is arranged on the rod at a position farther from the rear end of the inner sheath 70 than the position of the snare device 40 on the rod; or the moving unit 50 is an elongated rod, one end of the snare device 40 is fixedly connected to the end of the rod on the same side as the front end 21 of the inner sheath tube 70, and the embolectomy device 30 is fixedly connected to the other end of the snare device 40 (as shown in fig. 4 to 6). So that the cancer embolus 60 is separated from the tube wall 61 of the tumor patient with the cancer embolus 60 by the snare 40, and then the cancer embolus 60 is carried into the inner sheath 70 by the embolectomy device 30.

In other embodiments, as shown in fig. 7 to 9, there are two groups of inner sheath tubes 70, the moving unit 50 includes a first driving rod 51 and a second driving rod 52, both of which are elongated, the first driving rod 51 and the second driving rod 52 are movably and separately sleeved inside one group of inner sheath tubes 70, and both of which have a length greater than that of the inner sheath tubes 70; the embolectomy device 30 is fixedly connected to the end of the first transmission rod 51 located on the same side as the front end 21 of the sheath tube 20, and the snare device 40 is fixedly connected to the end of the second transmission rod 52 located on the same side as the front end 21 of the sheath tube 20. Therefore, when the front end of the inner sheath 70 passes through the cancer embolus 60 (as shown in fig. 13), the embolectomy device 30 can be driven by the first transmission rod 51 to move out of the inner sheath 70 from the end of the inner sheath 70 on the same side as the front end 21 of the outer sheath 20, and the snare device 40 can be driven by the second transmission rod 52 to move out of the inner sheath 70 from the end of the inner sheath 70 on the same side as the front end 21 of the outer sheath 20, and the movement time of the first transmission rod 51 and the second transmission rod 52 can be the same or different (as shown in fig. 14); then, while moving the inner sheath 70 toward the side of the outer sheath 20, the snare unit 40 is moved toward the side of the outer sheath 20 by the second drive rod 52 (as shown in fig. 15) until the snare unit 40 moves into the outer sheath 20, so that the cancer embolus 60 is separated from the wall 61 of the patient on which the cancer embolus 60 is grown by the contact of the snare unit 40 with the outer sheath 20 (as shown in fig. 16); then, the inner sheath 70 sleeved outside the first transmission rod 51 is moved towards the side where the outer sheath 20 is located, and at the same time, the first transmission rod 51 drives the embolectomy device 30 to move towards the side where the outer sheath 20 is located, so as to sleeve the cancer embolus 60 separated from the tube wall 61 (as shown in fig. 17), and move the cancer embolus 60 into the outer sheath 20 together while the embolectomy device 30 moves into the outer sheath 20 (as shown in fig. 18); finally, the outer sheath 20 containing the inner sheath 70, the embolectomy device 30, the snare device 40, and the cancer embolus 60 is removed from the patient, i.e., removal of the cancer embolus 60 is achieved. When the cancer embolus taking device extends into a patient body and is taken out from the patient body, the inner sheath tube 70, the embolus taking device 30 and the loop device 40 are all positioned inside the outer sheath tube 20, so that the outer diameter of the whole cancer embolus taking device is ensured to be smaller, the cancer embolus taking device is suitable for minimally invasive surgery, the wound of the patient is reduced, and the recovery of the patient is facilitated.

Preferably, in order to make the first transmission rod 51 and the second transmission rod 52 have certain strength and are not easy to deform, and can drive the bolt remover 30 and the snare device 40 to move relative to the inner sheath 70, the first transmission rod 51 and the second transmission rod 52 are made of metal, such as stainless steel; the diameter ranges from 1.5mm to 2 mm.

Preferably, as shown in fig. 7 and 8, the snare 40 is hexagonal, and one of the sharp corners of the hexagon is connected to the second transmission rod 52. Thereby, on the one hand, facilitating the snare 40 to return to the initial deployed state when removing the inner sheath 70; on the other hand, since the sharp corner of the hexagon is connected to the end of the second transmission rod 52, when the hexagonal snare device 40 is moved toward the sheath 20 by the second transmission rod 52 to contact the front end 21 of the sheath 20, the front end 21 of the sheath 20 applies pressure to two adjacent sides of the snare device 40 adjacent to the sharp corner connected to the second transmission rod 52 to achieve the contraction deformation of the snare device 40 by reducing the included angle between the two adjacent sides, so that the snare device 40 is in the second contracted state; the snare device 40 can move into the inner sheath 70 to recover the contracted state, so that the damage to the tube wall 61 of the patient caused by the contraction deformation of the hexagonal snare device 40 is small.

More preferably, as shown in fig. 11, the hexagonal shape of the ferrule holder 40 is formed in a plane that is inclined with respect to the second driving rod 52 by an angle ranging from 135 ° ± 15 °. Thereby facilitating the snare 40 to telescope from the head of the cancer plug 60 to the exterior of the cancer plug 60.

The connection mode in the invention is fixed connection, and can adopt non-detachable connection modes such as welding or gluing, and the like, and also can adopt detachable connection modes.

What has been described above are merely some embodiments of the present invention. It will be apparent to those skilled in the art that various changes and modifications can be made without departing from the inventive concept thereof, and these changes and modifications can be made without departing from the spirit and scope of the invention.

Claims

1. A cancer embolus removing device is characterized by comprising:

an outer sheath (20) which is capable of being placed in the portal vein and has two ends communicated with each other;

the two ends of the inner sheath tube (70) are communicated and movably sleeved in the outer sheath tube (20), and the length of the inner sheath tube (70) is greater than that of the outer sheath tube (20);

a moving unit (50) movably sleeved inside the inner sheath tube (70), wherein the length of the moving unit (50) is greater than that of the inner sheath tube (70);

a embolectomy device (30) provided at an end of the moving unit (50) for capturing a cancer embolus, the embolectomy device (30) being provided at an end of the moving unit (50) on the same side as a front end (21) of the sheath tube (20);

the embolectomy device (30) is made of a memory material capable of generating deformation, the moving unit (50) is arranged to drive the embolectomy device (30) to move back and forth relative to the inner sheath tube (70) along the axial direction of the inner sheath tube (70), so that when the embolectomy device (30) moves from the outside to the inside of the inner sheath tube (70), the embolectomy device (30) is changed from an initial expanded state to a contracted state, the initial expanded state of the embolectomy device (30) is arranged to be in a basket-shaped structure, an opening (301) of the basket-shaped structure faces the moving unit (50), and the embolectomy device (30) is further arranged to be capable of sleeving the front end of a cancer embolus (60) when in the initial expanded state;

a wire-frame-type snare (40) provided on the end of the moving unit (50) where the thrombectomy device (30) is provided.

2. The cancer embolectomy device of claim 1, wherein the snare device (40) is made of a memory material capable of generating a deformation, the moving unit (50) is configured to reciprocally move the snare device (40) relative to the inner sheath (70) along the axial direction of the inner sheath (70) so that the snare device (40) is transformed from an initial expanded state to a contracted state when the snare device (40) moves from the outside to the inside of the inner sheath (70), and the snare device (40) is further configured to be capable of sheathing the head of the cancer embolus (60) when the snare device is in the initial expanded state.

3. The cancer embolectomy device of claim 2, wherein the inner sheath tubes (70) are provided in two sets, the moving unit (50) comprises a first driving rod (51) and a second driving rod (52) which are both long-strip-shaped, the first driving rod (51) and the second driving rod (52) are both movably and separately sleeved inside one set of the inner sheath tubes (70), and the lengths of the first driving rod and the second driving rod are both longer than the length of the inner sheath tubes (70) sleeved outside the inner sheath tubes; wherein,

the bolt taking device (30) is arranged at the end part of the first transmission rod (51) which is positioned at the same side as the front end (21) of the sheath tube (20), and the ferrule device (40) is arranged at the end part of the second transmission rod (52) which is positioned at the same side as the front end (21) of the sheath tube (20).

4. The cancer embolectomy device of claim 3, wherein the snare (40) is hexagonal and one of the corners of the hexagon is connected to the second drive rod (52).

5. The cancer embolectomy device of claim 4, wherein the plane of the hexagon of the snare (40) is at an angle in the range of 135 ° ± 15 ° to the second drive rod (52).

6. The cancer embolus removing device of any one of claims 2 to 5, wherein the front end (21) of the sheath tube (20) is sleeved with a metal sheet (24) for cutting the cancer embolus (60) from the tube wall (61) of the tumor patient where the cancer embolus (60) is grown.

7. The cancer embolectomy device of claim 6, wherein the snare (40) is made of a titanium-nickel alloy, and the embolectomy device (30) is an umbrella-shaped basket woven from titanium-nickel wires.

8. The cancer embolectomy device of claim 7, wherein the diameter of the embolectomy device (30) and snare (40) in the expanded state is in the range of 8mm to 20 mm.

9. The cancer embolus removal device of claim 8, wherein the inside of the wire frame type snare (40) is provided with a cutting portion (401) for cutting a cancer embolus.

10. The cancer embolectomy device of claim 1, wherein the distal end (21) of the sheath (20) is curved to present the sheath (20) in a "J" shape.