CN110672861A - Multichannel glycosylated hemoglobin detector - Google Patents
Multichannel glycosylated hemoglobin detector Download PDFInfo
- Publication number
- CN110672861A CN110672861A CN201911067800.4A CN201911067800A CN110672861A CN 110672861 A CN110672861 A CN 110672861A CN 201911067800 A CN201911067800 A CN 201911067800A CN 110672861 A CN110672861 A CN 110672861A
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- liquid
- test
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- peristaltic pump
- controller
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- 102000017011 Glycated Hemoglobin A Human genes 0.000 title claims abstract description 21
- 108010014663 Glycated Hemoglobin A Proteins 0.000 title abstract description 7
- 238000012360 testing method Methods 0.000 claims abstract description 56
- 239000007788 liquid Substances 0.000 claims abstract description 52
- 238000001514 detection method Methods 0.000 claims abstract description 24
- 230000002572 peristaltic effect Effects 0.000 claims abstract description 19
- 239000012295 chemical reaction liquid Substances 0.000 claims abstract description 6
- 230000003287 optical effect Effects 0.000 claims abstract description 5
- 239000002699 waste material Substances 0.000 claims description 19
- 108091005995 glycated hemoglobin Proteins 0.000 claims description 14
- 230000005540 biological transmission Effects 0.000 claims description 12
- 230000002452 interceptive effect Effects 0.000 claims description 4
- 238000007599 discharging Methods 0.000 claims description 3
- 230000003993 interaction Effects 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 230000009286 beneficial effect Effects 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 238000009534 blood test Methods 0.000 description 1
- 238000004140 cleaning Methods 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 238000001802 infusion Methods 0.000 description 1
- 238000005342 ion exchange Methods 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/72—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood pigments, e.g. haemoglobin, bilirubin or other porphyrins; involving occult blood
- G01N33/721—Haemoglobin
- G01N33/723—Glycosylated haemoglobin
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/00584—Control arrangements for automatic analysers
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Hematology (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Pathology (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- General Physics & Mathematics (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Physics & Mathematics (AREA)
- Medicinal Chemistry (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Abstract
The invention discloses a multi-channel glycosylated hemoglobin detector, which comprises a detector body, wherein the detector body comprises a controller, a bracket and a detection mechanism supported by the bracket, the liquid path system, detection mechanism include the test tray and be used for driving the rotatory drive assembly of test tray, drive assembly by controller control, test tray include the disk body, and it has a plurality of notches that are used for bearing the test card to open on the disk body, lie in on the disk body notch department is provided with the clamp plate that is used for compressing tightly the test card, and the equipartition of circumferencial direction is followed to a plurality of notches, and the disk internal fixation is provided with the pick-up plate that is used for detecting test card optical value in the notch, and liquid path system includes peristaltic pump, liquid bottle and is used for adding the liquid feeding needle of reaction liquid to the test card in the notch, the peristaltic pump with controller electric connection, the liquid outlet of liquid bottle with the one end of peristaltic pump links to each other, the other end of peristaltic. The invention can realize multi-channel detection and has the characteristics of simple structure, low cost and high detection efficiency.
Description
Technical Field
The invention relates to the technical field of medical detection equipment, in particular to a multi-channel glycosylated hemoglobin detector.
Background
Currently, in the medical industry, the detection of glycated hemoglobin is classified into the following two categories:
1) in the case of a large test quantity, an automated instrument is generally adopted; the instrument usually adopts an ion exchange mode for detection and a whole blood test, has high speed and accurate result, but has larger volume, complex assembly, high cost and greatly limited application range;
2) under the condition of unstable test quantity, a handheld or small-sized detector is usually adopted, the instrument is usually detected by combining a test card with the instrument, the instrument is small in size, simple in structure and low in cost, and although the detection speed is low, the application range is wider.
However, the above-mentioned hand-held or small-sized detectors are generally single-channel detectors, and must wait for the previous test to complete before performing the next round of test, so the application range of the detector is still limited, and thus, the problem is urgently needed to be solved.
Disclosure of Invention
The invention aims to solve the problems that the conventional handheld or small-sized detector is used for single-channel detection, the next round of detection can be performed only after the previous detection is finished, and the application range of the detector is limited.
The purpose of the invention is realized by the following technical scheme:
a multi-channel glycosylated hemoglobin detector comprises a detector body, wherein the detector body comprises a controller, a support, a detection mechanism and a liquid path system, the detection mechanism and the liquid path system are supported by the support, the detection mechanism comprises a test disc and a driving assembly, the driving assembly is used for driving the test disc to rotate, the driving assembly is controlled by the controller, the test disc comprises a disc body, a plurality of notches for bearing test cards are formed in the disc body, pressing plates for pressing the test cards are arranged at the notches on the disc body, the notches are uniformly distributed along the circumferential direction, a detection plate for detecting the optical values of the test cards in the notches is fixedly arranged in the disc body, the liquid path system comprises a peristaltic pump, a liquid bottle and a liquid adding needle for adding reaction liquid to the test cards in the notches, the peristaltic pump is electrically connected with the controller, and the liquid outlet of the liquid bottle is connected with one end of the peristaltic pump, the other end of the peristaltic pump is connected with the liquid adding needle.
As a preferable scheme of the invention, the test disc is provided with a waste liquid through hole, and the support is provided with a waste liquid groove at a position corresponding to the waste liquid through hole.
In a preferred embodiment of the present invention, a waste liquid pipe for discharging waste liquid is connected to the waste liquid tank.
As a preferable scheme of the present invention, a photoelectric coupler for zeroing is fixedly disposed on an upper end surface of the bracket, and a zeroing block is disposed on a lower end surface of the test tray.
As a preferable scheme of the present invention, the detector body further includes an interactive system, the interactive system includes a touch screen and a printer, and the touch screen is electrically connected to the controller.
As a preferred scheme of the invention, the controller is a single chip microcomputer.
As a preferable scheme of the present invention, the driving assembly includes a driving motor, a driving wheel, a driven wheel, a belt, and a transmission shaft, the driving wheel is fixed on an output shaft of the driving motor, and the driving wheel is in transmission connection with the driven wheel through the belt, the driven wheel is fixedly mounted on the transmission shaft, and the test tray is fixed on the transmission shaft.
In a preferred embodiment of the present invention, the driving motor is a stepping motor with an encoder.
The multichannel glycosylated hemoglobin detector has the beneficial effects that the multichannel glycosylated hemoglobin detector can realize multichannel detection and has the characteristics of simple structure, low cost and high detection efficiency.
Drawings
FIG. 1 is a schematic view showing a configuration of a multi-channel glycated hemoglobin meter according to the present invention;
FIG. 2 is a sectional view of a multi-channel glycated hemoglobin meter according to the present invention.
Detailed Description
The technical scheme of the invention is further explained by the specific implementation mode in combination with the attached drawings. It is to be understood that the embodiments described herein are illustrative only and are not limiting upon the present invention.
Referring to fig. 1 and 2, fig. 1 is a schematic structural diagram of a multi-channel glycated hemoglobin detector according to the present invention; FIG. 2 is a sectional view of a multi-channel glycated hemoglobin meter according to the present invention.
In this embodiment, a multi-channel glycated hemoglobin detector includes a detector body, the detector body includes a controller, a bracket 1, and a detection mechanism, a liquid path system and an interaction system supported by the bracket 1, the interaction system includes a touch screen 2 and a printer 3, the touch screen 2 is electrically connected to the controller, the controller is a single chip microcomputer, the detection mechanism includes a test tray 4 and a driving component for driving the test tray 4 to rotate, the driving component includes a driving motor 15, a driving wheel 16, a driven wheel 17, a belt and a transmission shaft 18, the driving wheel 16 is fixed on an output shaft of the driving motor 15, the driving wheel 16 is in transmission connection with the driven wheel 17 through the belt, the driven wheel 17 is fixedly mounted on the transmission shaft 18, the test tray 4 is fixed on the transmission shaft 18, the driving motor 15 is a stepping motor with an encoder, just driving motor 15 with controller electric connection, test tray 4 includes disk body 19, it has 4 notches that are used for bearing test card 5 to open on the disk body 19, just lie in on the disk body 19 notch department is provided with the clamp plate 21 that is used for compressing tightly test card 5, 4 notch along the circumferencial direction equipartition, disk body 19 internal fixation is provided with the pick-up plate 20 that is used for detecting 5 optical value of test card in the notch, liquid route system includes peristaltic pump 6, liquid bottle 7 and is used for adding the liquid feeding needle 8 of reaction liquid to test card 5 in the notch, peristaltic pump 6 with controller electric connection, the liquid outlet of liquid bottle 7 through advance liquid pipeline 9 with peristaltic pump 6's one end links to each other, peristaltic pump 6's the other end through infusion pipeline 10 with add liquid needle 8 and link to each other.
In order to clean the pipeline conveniently, in this embodiment, the test tray 4 is provided with a waste liquid through hole 11, a waste liquid tank 12 is provided at a position corresponding to the waste liquid through hole 11 on the bracket 1, and a waste liquid pipe 13 for discharging waste liquid is connected to the waste liquid tank 12.
In order to ensure the smooth operation of the test, a photoelectric coupler 14 for zeroing is fixedly arranged on the upper end face of the bracket 1, and a zeroing block 22 is arranged on the lower end face of the test disc 4.
It should be noted that although the driving motor 15 is a stepping motor with an encoder in the embodiment, the present invention is not limited thereto, and the driving motor 15 may also be a servo motor or a dc motor with an encoder.
1) Starting up, the test disc 4 carries out self-checking and triggers the photoelectric coupler 14 to confirm the normal position through the zeroing block 22;
2) clicking a button for inserting the test card 5 on the touch screen 2;
3) the test disc 4 rotates until the pressure plate 21 samples the sample, and the test card 5 is inserted;
4) clicking a test button on the touch screen 2;
5) the test disc 4 rotates to enable the waste liquid through hole 11 to align with the position of the liquid adding needle 8, and at the moment, the peristaltic pump 6 is started to clean the pipeline;
6) after the cleaning is finished, the peristaltic pump 6 is closed, then the test disc 4 rotates until the pressure plate 21 is aligned with the position of the liquid adding needle 8, at the moment, the peristaltic pump 6 is opened, and reaction liquid is added to the test card 5;
7) the test disc 4 rotates until the pressure plate 21 loads the sample position, and the blood sample is loaded;
8) then, the test disc 4 rotates until the pressing plate 21 is aligned with the position of the liquid adding needle 8, and reaction liquid is continuously added;
9) finally, the detection board 20 detects the optical value of the test card 5, calculates the result and outputs the result to the touch screen 2;
10) and clicking the touch screen 2 to take out the test card 5, and completing the test.
The foregoing embodiments are merely illustrative of the principles and features of this invention, which is not limited to the above-described embodiments, but rather is susceptible to various changes and modifications without departing from the spirit and scope of the invention, which changes and modifications are within the scope of the invention as claimed. The scope of the invention is defined by the appended claims.
Claims (8)
1. The utility model provides a multichannel glycated hemoglobin detector, includes the detector body, its characterized in that: the detector body comprises a controller, a bracket, a detection mechanism and a liquid path system, wherein the detection mechanism and the liquid path system are supported by the bracket, the detection mechanism comprises a test disc and a driving component for driving the test disc to rotate, the driving component is controlled by the controller, the test tray comprises a tray body, a plurality of notches for bearing test cards are arranged on the tray body, a pressing plate for pressing the test card is arranged at the notch on the tray body, the notches are uniformly distributed along the circumferential direction, a detection plate for detecting the optical value of the test card in the notch is fixedly arranged in the disc body, the liquid path system comprises a peristaltic pump, a liquid bottle and a liquid adding needle for adding reaction liquid to the test card in the notch, the peristaltic pump is electrically connected with the controller, a liquid outlet of the liquid bottle is connected with one end of the peristaltic pump, and the other end of the peristaltic pump is connected with the liquid feeding needle.
2. The multi-channel glycated hemoglobin meter according to claim 1, wherein: the test disc is provided with a waste liquid through hole, and the support is provided with a waste liquid groove at a position corresponding to the waste liquid through hole.
3. The multi-channel glycated hemoglobin meter according to claim 2, wherein: and the waste liquid tank is connected with a waste liquid pipe for discharging waste liquid.
4. The multi-channel glycated hemoglobin meter according to claim 3, wherein: the upper end face of the support is fixedly provided with a photoelectric coupler for zeroing, and the lower end face of the test disc is provided with a zeroing block.
5. The multichannel glycated hemoglobin meter according to any one of claims 1 to 4, wherein: the detector body still includes interactive system, interactive system includes touch-sensitive screen and printer, the touch-sensitive screen with controller electric connection.
6. The multi-channel glycated hemoglobin meter according to claim 5, wherein: the controller is a single chip microcomputer.
7. The multi-channel glycated hemoglobin meter according to claim 6, wherein: the driving assembly comprises a driving motor, a driving wheel, a driven wheel, a belt and a transmission shaft, the driving wheel is fixed on an output shaft of the driving motor, the driving wheel is in transmission connection with the driven wheel through the belt, the driven wheel is fixedly installed on the transmission shaft, and the test disc is fixed on the transmission shaft.
8. The multi-channel glycated hemoglobin meter according to claim 7, wherein: the driving motor is a stepping motor with an encoder.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201911067800.4A CN110672861B (en) | 2019-11-04 | 2019-11-04 | Multichannel glycosylated hemoglobin detector |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201911067800.4A CN110672861B (en) | 2019-11-04 | 2019-11-04 | Multichannel glycosylated hemoglobin detector |
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| Publication Number | Publication Date |
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| CN110672861A true CN110672861A (en) | 2020-01-10 |
| CN110672861B CN110672861B (en) | 2023-11-07 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201911067800.4A Active CN110672861B (en) | 2019-11-04 | 2019-11-04 | Multichannel glycosylated hemoglobin detector |
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| CN (1) | CN110672861B (en) |
Cited By (4)
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| CN112213301A (en) * | 2020-09-15 | 2021-01-12 | 四川行之智汇知识产权运营有限公司 | Collecting and detecting device for hemoglobin in blood |
| CN112684124A (en) * | 2021-01-13 | 2021-04-20 | 六角体科技（天津）有限公司 | Many calories of food safety inspection equipment sampling device of high flux |
| CN113841054A (en) * | 2020-04-20 | 2021-12-24 | 利奥碧欧株式会社 | Glycated hemoglobin measurement apparatus and method |
| CN114371137A (en) * | 2022-01-12 | 2022-04-19 | 厦门大学 | Mark-free tumor marker detection system and method based on micro-nano structure optical chip |
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Cited By (5)
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| CN113841054A (en) * | 2020-04-20 | 2021-12-24 | 利奥碧欧株式会社 | Glycated hemoglobin measurement apparatus and method |
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| CN112684124A (en) * | 2021-01-13 | 2021-04-20 | 六角体科技（天津）有限公司 | Many calories of food safety inspection equipment sampling device of high flux |
| CN114371137A (en) * | 2022-01-12 | 2022-04-19 | 厦门大学 | Mark-free tumor marker detection system and method based on micro-nano structure optical chip |
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| Publication number | Publication date |
|---|---|
| CN110672861B (en) | 2023-11-07 |
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