CN110658102A - Brittle instrument - Google Patents
Brittle instrument Download PDFInfo
- Publication number
- CN110658102A CN110658102A CN201911047401.1A CN201911047401A CN110658102A CN 110658102 A CN110658102 A CN 110658102A CN 201911047401 A CN201911047401 A CN 201911047401A CN 110658102 A CN110658102 A CN 110658102A
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- Prior art keywords
- arc
- baffle
- cylinders
- cylinder
- hole
- Prior art date
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- Pending
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- 125000006850 spacer group Chemical group 0.000 claims abstract description 30
- 230000002093 peripheral effect Effects 0.000 claims abstract description 6
- 229920003023 plastic Polymers 0.000 claims description 6
- 239000000843 powder Substances 0.000 description 4
- 238000012360 testing method Methods 0.000 description 4
- 230000000694 effects Effects 0.000 description 2
- 238000002474 experimental method Methods 0.000 description 2
- 238000005192 partition Methods 0.000 description 2
- 239000004033 plastic Substances 0.000 description 2
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000000903 blocking effect Effects 0.000 description 1
- 238000005336 cracking Methods 0.000 description 1
- 238000012812 general test Methods 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000010298 pulverizing process Methods 0.000 description 1
- 238000004088 simulation Methods 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- 238000010998 test method Methods 0.000 description 1
- 230000004580 weight loss Effects 0.000 description 1
Images
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N5/00—Analysing materials by weighing, e.g. weighing small particles separated from a gas or liquid
- G01N5/04—Analysing materials by weighing, e.g. weighing small particles separated from a gas or liquid by removing a component, e.g. by evaporation, and weighing the remainder
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N19/00—Investigating materials by mechanical methods
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- Physics & Mathematics (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
Abstract
The invention discloses a friability instrument, which comprises a casing with a built-in rotating device, wherein cylinders driven by the rotating device are arranged on the left side and the right side of the casing, each cylinder is provided with an open outer side surface, an arc-shaped spacer is fixedly arranged on the inner side surface of each cylinder, each arc-shaped spacer extends to the inner peripheral wall of each cylinder from the circle center of each cylinder, and a plurality of mounting holes aligned with each other are formed in the arc-shaped spacers along the extending direction; the fragile instrument further comprises a baffle, the bottom of the baffle is provided with a connecting portion connected with the mounting hole in a matched mode, the baffle is detachably connected to the concave arc-shaped face of the arc-shaped spacer, and the width of the baffle is not smaller than the width of the arc-shaped spacer. Compared with the prior art, the falling height and the falling initial speed of the tablet can be changed by a user only by changing the position of the baffle, so that different transportation conditions of the tablet can be better simulated, and the applicability of the tablet is improved.
Description
Technical Field
The invention relates to the technical field of pharmaceutical equipment, in particular to a friability instrument.
Background
According to the chinese pharmacopoeia 2015 edition, the friability test method for tablets is used to test friability and other physical strengths of uncoated tablets and is a simulation of tablets during transport. The general test method is that a certain number of tablets are put on paper, then weighed and put into a cylinder of a friability apparatus, friability test is carried out, after the test is finished, the tablets and crumbled powder in the cylinder are poured on the paper, and sent to a sieve, crumbled powder is sieved, and the rest tablets are poured into the paper and weighed, and the weight loss of the tablets is not more than 1%, and the situation of fracture, cracking and pulverization is not caused.
Because the falling height and the falling initial speed of the tablets in the existing friability instrument are fixed, the prior art can not accurately simulate different transportation conditions of the tablets.
Disclosure of Invention
The invention aims to solve the technical problems that: provided is a friability apparatus capable of changing the drop height and initial drop speed of tablets.
The invention creates the solution for solving the technical problem that:
a fragile instrument comprises a machine shell internally provided with a rotating device, wherein cylinders driven by the rotating device are arranged on the left side and the right side of the machine shell, each cylinder is provided with an open outer side face, an arc-shaped spacer is fixedly arranged on the inner side face of each cylinder, the arc-shaped spacers extend to the inner peripheral wall of each cylinder from the circle center of each cylinder, and a plurality of mounting holes which are aligned with each other are formed in the arc-shaped spacers along the extending direction; the fragile instrument further comprises a baffle, the bottom of the baffle is provided with a connecting portion connected with the mounting hole in a matched mode, the baffle is detachably connected to the concave arc-shaped face of the arc-shaped spacer, and the width of the baffle is not smaller than the width of the arc-shaped spacer.
Furthermore, all vacant mounting holes are provided with first hole plugs.
Further, the connecting part comprises a screw and a nut matched with the screw for use, and the screw penetrates through the mounting hole.
Further, the cylinder, the arc-shaped spacer and the baffle are all made of transparent plastics.
Furthermore, the peripheral wall of the cylinder is provided with a through hole.
In addition, the through hole is positioned at the side of the convex arc surface of the arc-shaped spacer.
In addition, a second hole plug is arranged on the through hole.
Further, the left and right sides of casing all is equipped with two at least the drum, all drums that lie in same one side all set up side by side.
The beneficial effects of the invention are as follows: because the invention is provided with the baffle, when the cylinder filled with the tablets rotates, all the tablets are gathered outside the baffle when falling, compared with the prior art, a user can change the falling height and the falling initial speed of the tablets only by changing the position of the baffle, so that the invention can better simulate different transportation conditions of the tablets, and the applicability of the invention is improved. The invention is used for detecting the friability of tablets.
Drawings
In order to more clearly illustrate the technical solutions in the embodiments of the present invention, the drawings used in the description of the embodiments will be briefly described below. It is obvious that the described drawings are only a part of the embodiments of the invention, not all embodiments, and that a person skilled in the art will be able to derive other designs and drawings from these drawings without the exercise of inventive effort.
Fig. 1 is a schematic perspective view of an embodiment of a crisping instrument provided by the present invention;
FIG. 2 is another perspective view of an embodiment of the present invention;
FIG. 3 is a front view of one embodiment of the crisper provided by the present invention;
FIG. 4 is a left side view of one embodiment of the crisping instrument provided by the present invention;
fig. 5 is a front view of another embodiment of the crisping instrument provided by the invention.
In the drawings: 100-machine shell, 200-cylinder, 101-rotating shaft, 300-arc spacer, 210-central shaft, 310-mounting hole, 400-baffle, 410-connecting part, 110-switch, 120-control panel and 220-through hole.
Detailed Description
The conception, the specific structure and the technical effects of the present invention will be described clearly and completely with reference to the accompanying drawings and the embodiments, so that the objects, the features and the effects of the present invention can be fully understood. Obviously, the described embodiments are only a part of the embodiments of the present invention, and not all embodiments, and other embodiments obtained by those skilled in the art without any inventive work based on the embodiments of the present invention belong to the protection scope of the present invention. In addition, all the connection relations mentioned herein do not mean that the components are directly connected, but mean that a better connection structure can be formed by adding or reducing connection accessories according to the specific implementation situation. All technical characteristics in the invention can be interactively combined on the premise of not conflicting with each other. Finally, it should be noted that the terms "center, upper, lower, left, right, vertical, horizontal, inner, outer" and the like are used herein to indicate orientations or positional relationships based on the orientations or positional relationships shown in the drawings, and are only used for convenience of describing and simplifying the present invention, but do not indicate or imply that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and thus, should not be construed as limiting the present invention. Furthermore, the terms first, second and third as used herein are used for descriptive purposes only and are not to be construed as indicating or implying relative importance.
Fig. 1 to 4 show an embodiment of a crisper, comprising a housing 100 with a built-in rotating device (not shown in the drawings), which is not described in detail in the present invention since it is the same as the rotating device of the prior art; the left and right sides of the casing 100 are provided with cylinders 200 driven by the rotating device, and specifically, the rotating shaft 101 of the rotating device is fixedly connected with the cylinders 200, so that the cylinders 200 rotate along with the rotation of the rotating device. The cylinder 200 is provided with an open outer side surface, the inner side surface of the cylinder 200 is fixedly provided with an arc-shaped spacer 300, a user can directly place tablets on an inward concave arc-shaped surface of the arc-shaped spacer 300 from the outside, and the arc-shaped spacer 300 extends to the inner peripheral wall of the cylinder 200 from the center of the cylinder 200; specifically, a central shaft 210 located at the center of a circle is fixedly arranged on the inner side surface of the cylinder 200, one end of the arc-shaped spacer 300 is tangent to and fixedly connected with the central shaft 210, and the cylinder 200 is provided with a rotation direction which is turned from the concave arc-shaped surface to the convex arc-shaped surface of the arc-shaped spacer 300.
The arc-shaped spacer 300 is provided with a plurality of mounting holes 310 which are aligned with each other along the extending direction, the brittle failure instrument further comprises a baffle 400, the bottom of the baffle 400 is provided with a connecting part 410 which is matched and connected with the mounting holes 310, and the baffle 400 is detachably connected on the concave arc-shaped surface of the arc-shaped spacer 300; specifically, the connecting portion 410 includes a screw and a nut matched with the screw, the screw passes through the mounting hole 310, and a user only needs to screw the nut onto the screw to fixedly connect the baffle 400 to the arc-shaped spacer 300. In order to ensure that all tablets are gathered outside the baffle 400 when falling, the width of the baffle 400 is not less than the width of the arcuate partition 300, and in particular, the width of the baffle 400 is preferably identical to the width of the arcuate partition 300. In addition, the cylinder 200 and the arc-shaped spacers 300 are made of transparent plastic according to the requirements of the 'chinese pharmacopoeia' 2015 edition, but the baffle 400 is also made of transparent plastic including, but not limited to, transparent PVC, transparent PS, or transparent sub-force.
In addition, in order to prevent the tablet from passing through the mounting hole 310 or being stuck in the mounting hole 310, and thus blocking the mounting hole 310, all the empty mounting holes 310 are provided with a first hole plug (not shown in the drawings), which is specifically a plastic hole plug or a rubber hole plug.
It should be noted that the present invention is now applicable to conventional friability testing of tablets when a user removes the shield 400 and blocks all of the mounting holes 310.
In addition, a switch 110 and two control panels 120 arranged left and right are disposed on the front side of the housing 100, the control panels 120 are used for setting the rotation parameters of the cylinder 200, and the switch 110 is used for controlling the opening and closing of the rotating device.
In other embodiments, the circumferential wall of the cylinder 200 is provided with a through hole 220, the through hole 220 is used for pouring the tested tablets and crushed powder, and the through hole 220 is specifically located at the side of the outer convex arc surface of the arc-shaped spacer 300. In an actual experiment, since the tablets are not gathered at the position of the through hole 220, the user may not block the through hole 220 when the through hole 220 is used only to pour the tablets and the crushed powder after the experiment.
In other embodiments, as shown in fig. 5, in order to improve the working efficiency of the present invention, at least two cylinders 200 are disposed on both left and right sides of the casing 100, and all the cylinders 200 located on the same side are disposed side by side; all the cylinders 200 located on the same side are fixedly connected through respective central shafts 210, so that the rotating device can drive all the cylinders 200 on the left and right sides to rotate together. Although the number of the cylinders 200 is not limited by the invention, in order to ensure the stability of the invention, the number of the cylinders 200 is not more than six, and the left and right cylinders 200 are symmetrically arranged. In addition, when the number of the cylinders 200 on the same side is two or more, the through holes 220 may be used to insert tablets in order to facilitate the tablets to be placed into the cylinders 200; when the through hole 220 is used for placing tablets, a second hole plug (not shown in the drawings) is arranged on the through hole 220, and the second hole plug is specifically a plastic hole plug or a rubber hole plug.
While the preferred embodiments of the present invention have been described in detail, it will be understood by those skilled in the art that the invention is not limited to the details of the embodiments shown, but is capable of various modifications and substitutions without departing from the spirit of the invention.
Claims (8)
1. The utility model provides a fragile appearance which characterized in that: the device comprises a machine shell (100) with a built-in rotating device, wherein cylinders (200) driven by the rotating device are arranged on the left side and the right side of the machine shell (100), the cylinders (200) are provided with open outer side surfaces, arc-shaped spacers (300) are fixedly arranged on the inner side surfaces of the cylinders (200), the arc-shaped spacers (300) extend to the inner peripheral wall of the cylinders (200) from the circle centers of the cylinders (200), and a plurality of mutually aligned mounting holes (310) are formed in the arc-shaped spacers (300) in the extending direction; still include a baffle (400), the bottom of baffle (400) be equipped with mounting hole (310) accordant connection's connecting portion (410), baffle (400) releasable connection is on arc spacer (300) the indent arcwall face, the width of baffle (400) is not less than arc spacer (300) width.
2. A friability instrument according to claim 1, characterized in that: all the vacant mounting holes (310) are provided with first hole plugs.
3. A friability instrument according to claim 1, characterized in that: the connecting part (410) comprises a screw rod and a nut matched with the screw rod, and the screw rod penetrates through the mounting hole (310).
4. A friability instrument according to claim 1, characterized in that: the cylinder (200), the arc-shaped spacer (300) and the baffle (400) are all made of transparent plastics.
5. A friability instrument according to claim 1, characterized in that: the peripheral wall of the cylinder (200) is provided with a through hole (220).
6. A friability instrument according to claim 5, characterized in that: the through hole (220) is positioned at the side of the convex arc surface of the arc-shaped spacer (300).
7. A friability instrument according to claim 5, characterized in that: and a second hole plug is arranged on the through hole (220).
8. A friability instrument according to claim 1, characterized in that: the left side and the right side of the machine shell (100) are provided with at least two cylinders (200), and all the cylinders (200) positioned on the same side are arranged side by side.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201911047401.1A CN110658102A (en) | 2019-10-30 | 2019-10-30 | Brittle instrument |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201911047401.1A CN110658102A (en) | 2019-10-30 | 2019-10-30 | Brittle instrument |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN110658102A true CN110658102A (en) | 2020-01-07 |
Family
ID=69042422
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201911047401.1A Pending CN110658102A (en) | 2019-10-30 | 2019-10-30 | Brittle instrument |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN110658102A (en) |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3780994A (en) * | 1970-12-22 | 1973-12-25 | Sig Schweiz Industrieges | Method of and means for adjusting the flow of plastic material in an extruder cylinder |
| CN202281711U (en) * | 2011-05-04 | 2012-06-20 | 禄根仪器(镇江)有限公司 | Friability apparatus for tablet friability test |
| JP2015072211A (en) * | 2013-10-03 | 2015-04-16 | ダイヤリフォーム株式会社 | Concrete strength testing mold |
| CN105764492A (en) * | 2013-11-27 | 2016-07-13 | 维弗（国际）股份公司 | Pharmaceutical composition, comprising phosphate binder particles |
| CN211013908U (en) * | 2019-10-30 | 2020-07-14 | 佛山市第一人民医院（中山大学附属佛山医院） | Brittle instrument |
-
2019
- 2019-10-30 CN CN201911047401.1A patent/CN110658102A/en active Pending
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3780994A (en) * | 1970-12-22 | 1973-12-25 | Sig Schweiz Industrieges | Method of and means for adjusting the flow of plastic material in an extruder cylinder |
| CN202281711U (en) * | 2011-05-04 | 2012-06-20 | 禄根仪器(镇江)有限公司 | Friability apparatus for tablet friability test |
| JP2015072211A (en) * | 2013-10-03 | 2015-04-16 | ダイヤリフォーム株式会社 | Concrete strength testing mold |
| CN105764492A (en) * | 2013-11-27 | 2016-07-13 | 维弗（国际）股份公司 | Pharmaceutical composition, comprising phosphate binder particles |
| CN211013908U (en) * | 2019-10-30 | 2020-07-14 | 佛山市第一人民医院（中山大学附属佛山医院） | Brittle instrument |
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