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CN110339281A - A kind of Chinese medicine hemostatic formulations and preparation method thereof - Google Patents

A kind of Chinese medicine hemostatic formulations and preparation method thereof Download PDF

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Publication number
CN110339281A
CN110339281A CN201910692539.0A CN201910692539A CN110339281A CN 110339281 A CN110339281 A CN 110339281A CN 201910692539 A CN201910692539 A CN 201910692539A CN 110339281 A CN110339281 A CN 110339281A
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chinese medicine
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radix
rhizoma
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李玉成
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/045Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/612Crustaceans, e.g. crabs, lobsters, shrimps, krill or crayfish; Barnacles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K35/56Materials from animals other than mammals
    • A61K35/63Arthropods
    • A61K35/64Insects, e.g. bees, wasps or fleas
    • AHUMAN NECESSITIES
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232Angelica
    • AHUMAN NECESSITIES
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/237Notopterygium
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/238Saposhnikovia
    • AHUMAN NECESSITIES
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/25Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
    • A61K36/258Panax (ginseng)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/286Carthamus (distaff thistle)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/32Burseraceae (Frankincense family)
    • A61K36/324Boswellia, e.g. frankincense
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/32Burseraceae (Frankincense family)
    • A61K36/328Commiphora, e.g. mecca myrrh or balm of Gilead
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/33Cactaceae (Cactus family), e.g. pricklypear or Cereus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/56Loganiaceae (Logania family), e.g. trumpetflower or pinkroot
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
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    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/888Araceae (Arum family), e.g. caladium, calla lily or skunk cabbage
    • A61K36/8884Arisaema, e.g. Jack in the pulpit
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    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
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    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents

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Abstract

The invention discloses a kind of Chinese medicine hemostatic formulations and preparation method thereof, the Chinese medicine hemostatic formulations ingredient and consumption proportion are as follows: 3~4 parts of Rhizoma Chuanxiong, 1~3 part of Radix Angelicae Sinensis, 6~10 parts of frankincense, 6~8 parts of myrrh, 3~5 parts of arisaema cum bile, 1~3 part of ground beetle, 3~5 parts of dragon's blood, wild 3~5 parts of radix saposhnikoviae, 3~5 parts of crab claw bone, 3~5 parts of safflower, 1~3 part of Rhizoma Et Radix Notopterygii, 0.5~1 part of Semen Strychni (processed), 6~9 parts of Radix Notoginseng, 3~5 parts of Paris polyphylla, 3~5 parts of cimicifugae foetidae, 0.3~0.5 part of borneol, 9~12 parts of rhizoma cibotii.The preparation method comprises the following steps: taking all kinds of Chinese medicine drying millings of aforementioned proportion, be sieved 80 mesh, is packed into No. 1 capsule;Take all kinds of Chinese medicines of aforementioned proportion, will three times decocting liquid mix after, alcohol precipitation alcohol takes, be added carbomer, gel is made;All kinds of Chinese medicine low-temperature extractions of aforementioned proportion are taken, medical fluid is obtained, is made into spray-type.Formula haemostatic effect of the present invention is obvious, and is configured by Chinese medicine, and pharmacological property is mild, Small side effects.

Description

A kind of Chinese medicine hemostatic formulations and preparation method thereof
Technical field
The present invention relates to Chinese medicine preparation and preparation method thereof, a kind of Chinese medicine hemostatic formulations and preparation method thereof are specifically referred to.
Background technique
All drugs that can promote blood clotting and make stopped bleeding, referred to as hemostatic.Hemostatic mainly passes through in reinforcement Coagulation factor inhibits anticoagulant factor, promotes blood coagulation, to reach hemostasis purpose.Blood is in heart and Endovascular recycle stream A kind of dynamic tissue, the disease of all bleedings, especially Venous Arterial are bled profusely, such as effective not in time to prevent, and blood is caused to consume Damage, and cause body weak or even threat to life.So the application of hemostatic is of great significance.
Summary of the invention
The technical problem to be solved in the present invention is that providing a kind of Chinese medicine hemostatic formulations and preparation method thereof, haemostatic effect Obviously, and by Chinese medicine it configures, pharmacological property is mild, Small side effects.
The used technical solution is as follows:
A kind of Chinese medicine hemostatic formulations and preparation method thereof,
The Chinese medicine hemostatic formulations ingredient and consumption proportion are as follows: 3~4 parts of Rhizoma Chuanxiong, 1~3 part of Radix Angelicae Sinensis, 6~10 parts of frankincense, 6~8 parts of myrrh, 3~5 parts of arisaema cum bile, 1~3 part of ground beetle, 3~5 parts of dragon's blood, wild 3~5 parts of radix saposhnikoviae, 3~5 parts of crab claw bone, 3~5 parts of safflower, 1~3 part of Rhizoma Et Radix Notopterygii, 0.5~1 part of Semen Strychni (processed), 6~9 parts of Radix Notoginseng, 3~5 parts of Paris polyphylla, 3~5 parts of cimicifugae foetidae, borneol 0.3~0.5 part, 9~12 parts of rhizoma cibotii.
As further explanation,
The Chinese medicine hemostatic formulations ingredient and consumption proportion are as follows: 3 parts of Rhizoma Chuanxiong, 1 part of Radix Angelicae Sinensis, 6 parts of frankincense, myrrh 6 Part, 3 parts of arisaema cum bile, 1 part of ground beetle, 3 parts of dragon's blood, wild 3 parts of radix saposhnikoviae, 3 parts of crab claw bone, 3 parts of safflower, 1 part of Rhizoma Et Radix Notopterygii, Semen Strychni (processed) 0.5 part, 6 parts of Radix Notoginseng, 3 parts of Paris polyphylla, 3 parts of cimicifugae foetidae, 0.3 part of borneol, 9 parts of rhizoma cibotii.
As further explanation,
The Chinese medicine hemostatic formulations are milled the preparation method comprises the following steps: all kinds of Chinese medicines of aforementioned proportion is taken to dry, and be sieved 80 mesh, is packed into No. 1 capsule.
As further explanation,
The Chinese medicine hemostatic formulations the preparation method comprises the following steps: take all kinds of Chinese medicines of aforementioned proportion, will be after decocting liquid mixes three times, alcohol precipitation Alcohol takes, and carbomer is added, gel is made.
As further explanation,
The Chinese medicine hemostatic formulations the preparation method comprises the following steps: take all kinds of Chinese medicine low-temperature extractions of aforementioned proportion, obtain medical fluid, be made into Spray-type.
A kind of Chinese medicine hemostatic formulations of the present invention and preparation method thereof have the advantages that
1. formula of the present invention is used for palace blood, menorrhalgia, hemorrhoid blood, hematochezia, knife wound bleeding, bleeding from five sense organs or subcutaneous tissue, hemoptysis, alimentary canal Bleeding is intracranialed hemorrhage, the local application of soft tissue bruise and blood stasis and swelling pain, closed fracture and skin burn, scald.Match Rhizoma Chuanxiong, myrrh contained in side can stop blooding dissolving stasis, swelling and pain relieving;Frankincense can be with relaxing tendons and activating collaterals promoting the circulation of qi;Radix Notoginseng can be stopped Blood, blood-breaking dissipate the stasis of blood, anti-inflammatory analgesic therapy;Rhizoma cibotii can be used for rheumatic arthralgia, soreness and weakness of waist and knees.
It is small to injury of gastrointestinal tract 2. be formulated safety, Small side effects belonging to of the invention, can external application also oral administration, to liver kidney Dirty stimulation is small.
Specific embodiment
Technical solution of the present invention specifically, is completely illustrated below.
Embodiment 1:
Take 3 parts of Rhizoma Chuanxiong, it is 1 part of Radix Angelicae Sinensis, 6 parts of frankincense, 6 parts of myrrh, 3 parts of arisaema cum bile, 1 part of ground beetle, 3 parts of dragon's blood, wild 3 parts of radix saposhnikoviae, 3 parts of crab claw bone, 3 parts of safflower, 1 part of Rhizoma Et Radix Notopterygii, 0.5 part of Semen Strychni (processed), 6 parts of Radix Notoginseng, 3 parts of Paris polyphylla, 3 parts of cimicifugae foetidae, borneol 0.3 part, 9 parts of drying millings of rhizoma cibotii, be sieved 80 mesh, is packed into No. 1 capsule.
Embodiment 2:
Take 3 parts of Rhizoma Chuanxiong, it is 1 part of Radix Angelicae Sinensis, 6 parts of frankincense, 6 parts of myrrh, 3 parts of arisaema cum bile, 1 part of ground beetle, 3 parts of dragon's blood, wild 3 parts of radix saposhnikoviae, 3 parts of crab claw bone, 3 parts of safflower, 1 part of Rhizoma Et Radix Notopterygii, 0.5 part of Semen Strychni (processed), 6 parts of Radix Notoginseng, 3 parts of Paris polyphylla, 3 parts of cimicifugae foetidae, borneol 0.3 part, 9 parts of rhizoma cibotii will three times decocting liquid mix after, alcohol precipitation alcohol takes, be added carbomer, gel is made.
Embodiment 3:
Take 3 parts of Rhizoma Chuanxiong, it is 1 part of Radix Angelicae Sinensis, 6 parts of frankincense, 6 parts of myrrh, 3 parts of arisaema cum bile, 1 part of ground beetle, 3 parts of dragon's blood, wild 3 parts of radix saposhnikoviae, 3 parts of crab claw bone, 3 parts of safflower, 1 part of Rhizoma Et Radix Notopterygii, 0.5 part of Semen Strychni (processed), 6 parts of Radix Notoginseng, 3 parts of Paris polyphylla, 3 parts of cimicifugae foetidae, borneol 0.3 part, 9 parts of low-temperature extractions of rhizoma cibotii obtain medical fluid, are made into spray-type.
1. formula of the present invention is used for palace blood, menorrhalgia, hemorrhoid blood, hematochezia, knife wound bleeding, bleeding from five sense organs or subcutaneous tissue, hemoptysis, alimentary canal Bleeding is intracranialed hemorrhage, the local application of soft tissue bruise and blood stasis and swelling pain, closed fracture and skin burn, scald.Match Rhizoma Chuanxiong, myrrh contained in side can stop blooding dissolving stasis, swelling and pain relieving;Frankincense can be with relaxing tendons and activating collaterals promoting the circulation of qi;Radix Notoginseng can be stopped Blood, blood-breaking dissipate the stasis of blood, anti-inflammatory analgesic therapy;Rhizoma cibotii can be used for rheumatic arthralgia, soreness and weakness of waist and knees.
It is small to injury of gastrointestinal tract 2. be formulated safety, Small side effects belonging to of the invention, can external application also oral administration, to liver kidney Dirty stimulation is small.
The foregoing describe basic principles and main features of the invention, It should be understood by those skilled in the art that of the invention It is not restricted to the described embodiments, the above embodiments and description only illustrate the principle of the present invention, is not departing from Under the premise of spirit and scope of the invention, various changes and improvements may be made to the invention, these changes and improvements both fall within requirement In the scope of the invention of protection, invents claimed range and be defined by the appending claims and its equivalent thereof.

Claims (5)

1. a kind of Chinese medicine hemostatic formulations and preparation method thereof, which is characterized in that the Chinese medicine hemostatic formulations ingredient and consumption proportion Are as follows: 3~4 parts of Rhizoma Chuanxiong, 1~3 part of Radix Angelicae Sinensis, 6~10 parts of frankincense, 6~8 parts of myrrh, 3~5 parts of arisaema cum bile, ground beetle 1~3 Part, 3~5 parts of dragon's blood, wild 3~5 parts of radix saposhnikoviae, 3~5 parts of crab claw bone, 3~5 parts of safflower, 1~3 part of Rhizoma Et Radix Notopterygii, Semen Strychni (processed) 0.5~1 Part, 6~9 parts of Radix Notoginseng, 3~5 parts of Paris polyphylla, 3~5 parts of cimicifugae foetidae, 0.3~0.5 part of borneol, 9~12 parts of rhizoma cibotii.
2. a kind of Chinese medicine hemostatic formulations according to claim 1 and preparation method thereof, which is characterized in that the Chinese medicine stops Blood formula components and consumption proportion are as follows: 3 parts of Rhizoma Chuanxiong, 1 part of Radix Angelicae Sinensis, 6 parts of frankincense, 6 parts of myrrh, 3 parts of arisaema cum bile, ground beetle 1 Part, 3 parts of dragon's blood, wild 3 parts of radix saposhnikoviae, 3 parts of crab claw bone, 3 parts of safflower, 1 part of Rhizoma Et Radix Notopterygii, 0.5 part of Semen Strychni (processed), 6 parts of Radix Notoginseng, 3 parts of Paris polyphylla, 3 parts of cimicifugae foetidae, 0.3 part of borneol, 9 parts of rhizoma cibotii.
3. a kind of Chinese medicine hemostatic formulations according to claim 1 and preparation method thereof, which is characterized in that the Chinese medicine hemostasis Formula is milled the preparation method comprises the following steps: all kinds of Chinese medicines of aforementioned proportion is taken to dry, and be sieved 80 mesh, is packed into No. 1 capsule.
4. a kind of Chinese medicine hemostatic formulations according to claim 1 and preparation method thereof, which is characterized in that the Chinese medicine hemostasis Formula the preparation method comprises the following steps: take all kinds of Chinese medicines of aforementioned proportion, will be after decocting liquid mixes three times, alcohol precipitation alcohol takes, and carbomer is added, is made Gel.
5. a kind of Chinese medicine hemostatic formulations according to claim 1 and preparation method thereof, which is characterized in that the Chinese medicine hemostasis Formula the preparation method comprises the following steps: take all kinds of Chinese medicine low-temperature extractions of aforementioned proportion, obtain medical fluid, be made into spray-type.
CN201910692539.0A 2019-07-30 2019-07-30 A kind of Chinese medicine hemostatic formulations and preparation method thereof Pending CN110339281A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112089794A (en) * 2020-10-30 2020-12-18 广东宇通医药生物科技有限公司 Traditional Chinese medicine hemostatic formula and preparation method thereof

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1066783A (en) * 1991-05-13 1992-12-09 赵俊光 The preparation method of traumatic quick result medicine
CN101181526A (en) * 2007-11-26 2008-05-21 倪建忠 Medical hongshang hemostatic medicament and preparation method thereof
CN103989864A (en) * 2014-04-30 2014-08-20 烟台恒迪克能源科技有限公司 Externally-applied pain-relieving swelling-removing ointment for traumatic injuries and preparation method thereof

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1066783A (en) * 1991-05-13 1992-12-09 赵俊光 The preparation method of traumatic quick result medicine
CN101181526A (en) * 2007-11-26 2008-05-21 倪建忠 Medical hongshang hemostatic medicament and preparation method thereof
CN103989864A (en) * 2014-04-30 2014-08-20 烟台恒迪克能源科技有限公司 Externally-applied pain-relieving swelling-removing ointment for traumatic injuries and preparation method thereof

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112089794A (en) * 2020-10-30 2020-12-18 广东宇通医药生物科技有限公司 Traditional Chinese medicine hemostatic formula and preparation method thereof

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Application publication date: 20191018