CN110239804B - Piercing device and microfluidic device - Google Patents
Piercing device and microfluidic device Download PDFInfo
- Publication number
- CN110239804B CN110239804B CN201910649387.6A CN201910649387A CN110239804B CN 110239804 B CN110239804 B CN 110239804B CN 201910649387 A CN201910649387 A CN 201910649387A CN 110239804 B CN110239804 B CN 110239804B
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- assembly
- connecting block
- fluid bag
- puncturing
- pressure lever
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- 239000012530 fluid Substances 0.000 claims abstract description 43
- 238000006243 chemical reaction Methods 0.000 claims abstract description 16
- 238000007789 sealing Methods 0.000 claims abstract description 16
- 239000007788 liquid Substances 0.000 claims abstract description 12
- 230000005540 biological transmission Effects 0.000 claims description 16
- 230000006835 compression Effects 0.000 claims description 12
- 238000007906 compression Methods 0.000 claims description 12
- 230000007246 mechanism Effects 0.000 claims description 10
- 239000012528 membrane Substances 0.000 claims description 7
- 229920001296 polysiloxane Polymers 0.000 claims description 7
- 238000001514 detection method Methods 0.000 abstract description 2
- 238000000034 method Methods 0.000 description 7
- 230000008569 process Effects 0.000 description 5
- 230000033001 locomotion Effects 0.000 description 4
- 239000002994 raw material Substances 0.000 description 3
- 230000009471 action Effects 0.000 description 2
- 230000009286 beneficial effect Effects 0.000 description 2
- 230000000994 depressogenic effect Effects 0.000 description 2
- 238000002955 isolation Methods 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 238000004891 communication Methods 0.000 description 1
- 238000001125 extrusion Methods 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 238000009434 installation Methods 0.000 description 1
- 238000002156 mixing Methods 0.000 description 1
Classifications
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
- B65B69/00—Unpacking of articles or materials, not otherwise provided for
- B65B69/0033—Unpacking of articles or materials, not otherwise provided for by cutting
- B65B69/0041—Unpacking of articles or materials, not otherwise provided for by cutting by puncturing
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/10—Integrating sample preparation and analysis in single entity, e.g. lab-on-a-chip concept
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- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Dispersion Chemistry (AREA)
- Analytical Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Hematology (AREA)
- Clinical Laboratory Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Mechanical Engineering (AREA)
- Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
Abstract
The application relates to the field of biological detection, in particular to a puncturing device and microfluidic equipment. The puncture device is used for sealing chemical reaction and comprises a puncture assembly, a sealing assembly and a driving assembly; the driving assembly is connected with the puncturing assembly and can drive the working end of the puncturing assembly to move towards or away from the fluid bag; the sealing assembly is arranged between the puncturing assembly and the fluid bag and is used for keeping the puncturing assembly isolated from liquid flowing out of the fluid bag when the puncturing assembly punctures the fluid bag and is far away from the fluid bag. The valve and pipeline type valve solves the problems that in the prior art, difficulties in product assembly and design are high, and therefore the price of products is high and popularization and application are not facilitated.
Description
Technical Field
The application relates to the field of biological detection, in particular to a puncturing device and microfluidic equipment.
Background
For the chemical reaction of a closed system, the reaction environment is isolated from the outside, the added reaction raw materials can only be stored in the reactor in a space isolated manner, and then released to form contact and mixing when needed to react.
The key requirement for the mode is that the method can safely and stably store various raw materials and conveniently and quickly eliminate space isolation. The valve and the pipeline are designed to realize the addition of the reaction raw materials in the reaction of the sealing body, but the valve and the pipeline are difficult to assemble and design the product, so that the price of the product is high and the popularization and the application are not facilitated.
Disclosure of Invention
The embodiment of the application aims to provide a puncturing device which has a simple structure, is convenient to assemble and operate, and is beneficial to popularization and application.
In a first aspect, embodiments of the present invention provide a lancing device for use in sealing a chemical reaction, comprising a lancing assembly, a sealing assembly and a driving assembly;
the driving assembly is connected with the puncturing assembly and can drive the working end of the puncturing assembly to move towards or away from the fluid bag;
The sealing assembly is arranged between the puncturing assembly and the fluid bag and is used for keeping the puncturing assembly isolated from liquid flowing out of the fluid bag when the puncturing assembly punctures the fluid bag and is far away from the fluid bag.
In an alternative embodiment, the lancing assembly further includes a plurality of lever arms;
each pressure lever arm is provided with at least one working end, one side of each pressure lever arm is provided with at least one connecting piece used for being abutted with the driving component, the other side of each pressure lever arm is provided with a reset spring, and the driving component can extrude the connecting piece and compress the reset spring so that the pressure lever arms reciprocate up and down.
In an alternative embodiment, the drive assembly includes a drive mechanism and a slider;
The slider is located the one end of depression bar arm, be equipped with the depressed part on the slider, when the connecting piece with the depressed part cooperates, reset spring resets.
In an alternative embodiment, the driving mechanism comprises a driving motor, a transmission piece, a screw rod and a linkage seat;
one end of the transmission piece is connected with the output end of the driving motor, the other end of the transmission piece is connected with the screw rod, the linkage seat is arranged on the screw rod, and the linkage seat can reciprocate along the extending direction of the screw rod;
the linkage seat is connected with the sliding block.
In an alternative embodiment, the driving mechanism further comprises a supporting seat, the supporting seat is arranged at one end close to the transmission piece, and the screw rod penetrates through the supporting seat to be connected with the linkage seat.
In an alternative embodiment, the lancing assembly further comprises a shaft;
The three pressure lever arms are arranged at intervals in parallel, one ends of the three pressure lever arms are rotationally connected with the rotating shaft, at least one working end is arranged at the other ends of the three pressure lever arms, and connecting lines of connecting pieces at the upper ends of the adjacent two pressure lever arms are not on the same straight line.
In an alternative embodiment, the puncture device further comprises a base, three positioning grooves for being matched with the compression bar arms are formed in the base, the rotation shaft penetrates through the three positioning grooves to fix the three compression bar arms, at least one guide rail connected with the sliding block is arranged above the positioning grooves, and the extending direction of the guide rail is the same as that of the positioning grooves.
In an alternative embodiment, the slider includes a body, a first connection block, a second connection block, and a third connection block;
The first connecting block, the second connecting block and the third connecting block are arranged at intervals, the main body is close to one end of the pressure lever arm, the first connecting block, the second connecting block and one end of the third connecting block are arranged at the end part of the main body, the first connecting block, the second connecting block and the other end of the third connecting block are all inclined planes, two first grooves matched with connecting pieces on the pressure lever arm are formed in the extending direction of the first connecting block, and one second groove matched with the connecting pieces on the pressure lever arm is formed in the second connecting block.
In an alternative embodiment, a reset sensor is arranged on the base, the reset sensor is arranged on one side of the base, and the reset sensor is used for resetting the linkage seat.
In an alternative embodiment, the seal assembly is a silicone membrane.
It is a further object of the present invention to provide a microfluidic device having a lancing device as described above.
Through above-mentioned technical scheme, drive assembly can drive the motion of the work end of piercing assembly to the fluid package to prick the fluid package so that the liquid in the fluid package flows, carry out chemical reaction, need not carry out chemical reaction through the mode of pipeline and valve like this, seal assembly is between the work end of piercing assembly and the fluid package in addition, makes the liquid in the fluid package be in airtight environment in the in-process of flowing out and reacting, ensures the accuracy of reaction.
Drawings
In order to more clearly illustrate the technical solutions of the embodiments of the present application, the drawings that are needed in the embodiments of the present application will be briefly described below, it should be understood that the following drawings only illustrate some embodiments of the present application and should not be considered as limiting the scope, and other related drawings can be obtained according to these drawings without inventive effort for a person skilled in the art.
FIG. 1 is a perspective view of a lancing device according to an embodiment of the present application;
FIG. 2 is a cross-sectional view of a lancing device according to an embodiment of the present application;
FIG. 3 is a schematic illustration of a lancing device according to an embodiment of the present application with a slider coupled to a lancing assembly;
fig. 4 is a schematic structural view of a slider of a lancing device according to an embodiment of the present application;
FIG. 5 is a cross-sectional view of a lancing device according to an embodiment of the present application when a working end of the lancing assembly is lancing a fluid package.
Icon: 100-piercing assembly; 110-lever arms; 120-working end; 130-a connector; 140-a return spring; 150-rotating shaft; 200-a drive assembly; 210-driving a motor; 220-a transmission member; 230-screw rod; 240-linkage seat; 250-slide block; 251-a body; 252-first connection block; 253-a second connection block; 254-a third connection block; 260-a support base; 300-a seal assembly; 400-base; 410-a guide rail; 420-resetting the sensor; 500-fluid packet.
Detailed Description
In order to make the objects, technical solutions and advantages of the embodiments of the present application more clear, the technical solutions of the embodiments of the present application will be clearly and completely described below with reference to the accompanying drawings in the embodiments of the present application. It will be apparent that the described embodiments are some, but not all, embodiments of the application. The components of the embodiments of the present application generally described and illustrated in the figures herein may be arranged and designed in a wide variety of different configurations.
In the description of the present application, it should be noted that, the azimuth or positional relationship indicated by the terms "inner", "outer", etc. are based on the azimuth or positional relationship shown in the drawings, or the azimuth or positional relationship that is commonly put in use of the product of this application, are merely for convenience of describing the present application and simplifying the description, and do not indicate or imply that the device or element to be referred to must have a specific azimuth, be configured and operated in a specific azimuth, and therefore should not be construed as limiting the present application. Furthermore, the terms "first," "second," and the like, are used merely to distinguish between descriptions and should not be construed as indicating or implying relative importance.
In the description of the present application, it should also be noted that, unless explicitly specified and limited otherwise, the terms "disposed", "connected" and "connected" are to be construed broadly, and may be, for example, fixedly connected, detachably connected or integrally connected; can be directly connected or indirectly connected through an intermediate medium, and can be communication between two elements. The specific meaning of the above terms in the present application will be understood in specific cases by those of ordinary skill in the art.
As shown in fig. 1-3 and 5, a lancing device for use in sealing a chemical reaction includes a lancing assembly 100, a sealing assembly 300, and a drive assembly 200; the drive assembly 200 is coupled to the lancing assembly 100, the drive assembly 200 being capable of driving the working end 120 of the lancing assembly 100 toward or away from the fluid packet 500; the seal assembly 300 is disposed between the lancing assembly 100 and the fluid package 500, the seal assembly 300 being configured to maintain isolation of the lancing assembly 100 from liquid flowing from the fluid package 500 when the lancing assembly 100 is lancing the fluid package and is remote from the fluid package 500.
Wherein the seal assembly 300 is preferably a silicone membrane. When the silicone membrane is subjected to the force of the working end 120 of the piercing assembly 100 moving towards the end close to the fluid bag 500, the silicone membrane is deformed only when the piercing assembly 100 pierces the fluid bag 500 due to the characteristics of the silicone membrane, and the silicone membrane cannot be pierced by the working end 120 of the piercing assembly 100, so that the reaction space is still a closed space when the liquid in the fluid bag 500 flows out.
Because the micro-channel sealing film at the bottom of the liquid bag is a soft film, the unsealing needle can continuously upwards penetrate through the micro-channel sealing film at the bottom of the liquid bag and can not be stained with the solution in the cavity of the liquid bag component.
In this embodiment, the driving assembly 200 can drive the working end 120 of the lancing assembly 100 to move toward the fluid package 500, and puncture the fluid package 500 to make the liquid in the fluid package 500 flow out for chemical reaction, so that the chemical reaction does not need to be performed by a pipeline and a valve, and the sealing assembly 300 is between the working end 120 of the lancing assembly 100 and the fluid package 500, so that the liquid in the fluid package 500 is in a sealed environment during the flowing out and reacting process, thereby ensuring the accuracy of the reaction.
In an alternative embodiment, the lancing assembly 100 further includes a plurality of lever arms 110; each of the compression bar arms 110 is provided with at least one working end 120, one side of each of the compression bar arms 110 is provided with at least one connecting piece 130 for abutting against the driving assembly 200, the other side is provided with a return spring 140, and the driving assembly 200 can squeeze the connecting piece 130 and compress the return spring 140 so as to enable the compression bar arms 110 to reciprocate up and down.
One end of the connecting member 130 abutting against the driving assembly 200 is a bearing or a roller, so as to generate friction between the connecting member 130 and the driving assembly 200.
In addition, the working end 120 is a tamper evident needle.
In this embodiment, the driving assembly 200 can abut against the outer contour of the connecting piece 130 and generate a pressing force on the lever arm 110 during the movement, and due to the arrangement of the return spring 140, the lever arm 110 can form a corresponding movement track along with the movement of the driving assembly 200, so as to drive the working end 120 of the lever arm 110 to move towards the position of the fluid package 500 and restore to achieve the function of puncturing the fluid package 500.
In an alternative embodiment, the drive assembly 200 includes a drive mechanism and a slider 250; the slider 250 is located at one end of the compression bar arm 110, a recess is provided on the slider 250, and when the connector 130 is matched with the recess, the return spring 140 is reset.
The number of the concave parts can be one, two or three, and the like, and the concave parts can be adjusted according to specific requirements.
In this embodiment, the driving mechanism drives the slider 250 to slide, and the sliding direction of the slider 250 is the same as the extending direction of the lever arm 110, so that in the sliding process of the slider 250, the connecting piece 130 receives the extrusion force of the slider 250, so that the working end 120 of the lever arm 110 can move to the position where the fluid bag 500 is located, and because the lower end of the lever arm 110 is provided with the return spring 140, when the connecting piece 130 passes through the recess, the return spring 140 returns, and the working end 120 is far away from the fluid bag 500.
In an alternative embodiment, the driving mechanism includes a driving motor 210, a transmission member 220, a screw 230, and a linkage seat 240; one end of the transmission member 220 is connected with the output end of the driving motor 210, the other end of the transmission member 220 is connected with the screw 230, the linkage seat 240 is mounted on the screw 230, and the linkage seat 240 can reciprocate along the extending direction of the screw 230; the linkage seat 240 is connected with the slider 250.
Wherein the transmission member 220 is preferably a gear transmission.
In this embodiment, the driving motor 210 drives the screw rod 230 to rotate through the transmission member 220, and the screw rod 230 is connected with the linkage seat 240, and when the screw rod 230 rotates, the linkage seat 240 is connected with the slider 250, so as to drive the slider 250 to move, so as to realize that the working end 120 connected to the pressure lever arm 110 pierces and returns the fluid bag 500.
In an alternative embodiment, the driving mechanism further includes a support base 260, the support base 260 is disposed near one end of the transmission member 220, and the screw 230 passes through the support base 260 to be connected with the linkage base 240.
In this embodiment, the convenience of the screw 230 during installation can be improved by the support base 260, and the stability of the screw 230 during rotation can be ensured.
In an alternative embodiment, the lancing assembly 100 further includes a spindle 150; the number of the pressure lever arms 110 is three, the three pressure lever arms 110 are arranged at intervals in parallel, one ends of the three pressure lever arms 110 are rotationally connected with the rotating shaft 150, at least one working end 120 is arranged at the other ends of the three pressure lever arms 110, and connecting lines of the connecting pieces 130 at the upper ends of two adjacent pressure lever arms 110 are not in the same straight line.
As shown in fig. 4, further, the slider 250 includes a main body 251, a first connection block 252, a second connection block 253, and a third connection block 254; the first connecting block 252, the second connecting block 253 and the third connecting block 254 are arranged at intervals at one end of the main body 251, which is close to the compression bar arm 110, one end of the first connecting block 252, one end of the second connecting block 253 and one end of the third connecting block 254 are arranged at the end of the main body 251, the other ends of the first connecting block 252, the second connecting block 253 and the third connecting block 254 are all inclined planes, two first grooves matched with the connecting piece 130 on the compression bar arm 110 are arranged along the extending direction of the first connecting block 252, and a second groove matched with the connecting piece 130 on the compression bar arm 110 is arranged on the second connecting block 253.
In this embodiment, the number of the press lever arms 110 is preferably three, one ends of the three press lever arms 110 are connected through the rotating shaft 150, at least one working end 120 is disposed on each of the three press lever arms 110, a first connecting block 252, a second connecting block 253 and a third connecting block 254 are disposed at one end of the slider 250 capable of contacting with the press lever arms 110, in the process of moving the main body 251, one ends of the first connecting block 252, the second connecting block 253 and the third connecting block 254 are disposed in inclined planes, so that the connecting pieces 130 disposed on the press lever arms 110 can slide onto the first connecting block 252, the second connecting block 253 and the third connecting block 254 better, and at least two connecting pieces 130 on two press lever arms 110 are matched with the first grooves and the second grooves disposed on the first connecting block 252 and the second connecting block 253, so that the working ends 120 of two press lever arms 110 can stretch out and draw back in a unidirectional sliding process of the slider 250.
In an alternative embodiment, the lancing device further includes a base 400, three positioning grooves for matching with the lever arms 110 are provided on the base 400, the rotating shaft 150 passes through the three positioning grooves to fix the three lever arms 110, at least one guide rail 410 connected with the slider 250 is provided above the positioning grooves, and the extending direction of the guide rail 410 is the same as the extending direction of the positioning grooves.
Wherein, the base 400 is provided with at least one guiding hole, the guiding hole corresponds to the working end 120 of the piercing assembly 100, and the working end 120 can stretch and retract along the guiding hole, so that the fluid package 500 is pierced.
In this embodiment, a positioning groove is provided on the base 400, the positioning groove can enable the three pressure lever arms 110 to be rotatably arranged, so that the overall stability is better, in addition, the arrangement of the guide rail 410 can enable the slider 250 to slide along the extending direction of the guide rail 410, so that the slider is ensured to be abutted against the connecting piece 130 on the pressure lever arm 110 in the moving process, and the working end 120 on the pressure lever arm 110 is driven to puncture the fluid bag 500.
In an alternative embodiment, a reset sensor 420 is provided on the base 400, the reset sensor 420 is provided on one side of the base 400, and the reset sensor 420 is used for resetting the linkage seat 240.
In this embodiment, the reset sensor 420 is configured to enable the whole device to recover to the original position after performing the action of puncturing the fluid bag 500 once, so as to ensure that the actions of each operation are the same.
It is a further object of the present invention to provide a microfluidic device having a lancing device as described above. The beneficial effects generated by the device are the same as those of the puncturing device, and are not repeated.
It should be noted that the features of the embodiments of the present application may be combined with each other without conflict.
The above description is only of the preferred embodiments of the present application and is not intended to limit the present application, but various modifications and variations can be made to the present application by those skilled in the art. Any modification, equivalent replacement, improvement, etc. made within the spirit and principle of the present application should be included in the protection scope of the present application.
Claims (5)
1. A lancing device for use in sealing a chemical reaction, comprising a lancing assembly, a sealing assembly and a drive assembly;
the driving assembly is connected with the puncturing assembly and can drive the working end of the puncturing assembly to move towards or away from the fluid bag;
The sealing assembly is arranged between the puncturing assembly and the fluid bag and is used for keeping the puncturing assembly isolated from liquid flowing out of the fluid bag when the puncturing assembly punctures the fluid bag and is far away from the fluid bag;
The lancing assembly further includes a plurality of lever arms;
Each pressure lever arm is provided with at least one working end, one side of each pressure lever arm is provided with at least one connecting piece used for being abutted against the driving component, the other side of each pressure lever arm is provided with a reset spring, and the driving component can squeeze the connecting piece and compress the reset spring so as to enable the pressure lever arms to reciprocate up and down;
the driving assembly comprises a driving mechanism and a sliding block;
the sliding block is positioned at one end of the compression bar arm, a connecting piece concave part is arranged on the sliding block, and when the connecting piece is matched with the concave part, the reset spring is reset;
the driving mechanism comprises a driving motor, a transmission piece, a screw rod and a linkage seat;
one end of the transmission piece is connected with the output end of the driving motor, the other end of the transmission piece is connected with the screw rod, the linkage seat is arranged on the screw rod, and the linkage seat can reciprocate along the extending direction of the screw rod;
The linkage seat is connected with the sliding block;
The driving mechanism further comprises a supporting seat, the supporting seat is arranged at one end close to the transmission piece, and the screw rod penetrates through the supporting seat to be connected with the linkage seat;
the puncture assembly further comprises a rotating shaft;
The three press lever arms are arranged in parallel at intervals, one ends of the three press lever arms are rotationally connected with the rotating shaft, at least one working end is arranged at the other ends of the three press lever arms, and connecting lines of connecting pieces at the upper ends of two adjacent press lever arms are not in the same straight line;
The sliding block comprises a main body, a first connecting block, a second connecting block and a third connecting block;
The first connecting block, the second connecting block and the third connecting block are arranged at intervals, the main body is close to one end of the pressure lever arm, the first connecting block, the second connecting block and one end of the third connecting block are arranged at the end part of the main body, the first connecting block, the second connecting block and the other end of the third connecting block are all inclined planes, two first grooves matched with connecting pieces on the pressure lever arm are formed in the extending direction of the first connecting block, and one second groove matched with the connecting pieces on the pressure lever arm is formed in the second connecting block.
2. The lancing device according to claim 1, further comprising a base, wherein three positioning grooves for being matched with the three compression bar arms are formed in the base, the rotation shaft penetrates through the three positioning grooves to fix the three compression bar arms, at least one guide rail connected with the sliding block is arranged above the positioning grooves, and the extending direction of the guide rail is the same as the extending direction of the positioning grooves.
3. The lancing device of claim 2, wherein a reset sensor is disposed on the base, the reset sensor being disposed on one side of the base, the reset sensor being configured to reset the linkage seat.
4. The lancing device of claim 1, wherein the sealing assembly is a silicone membrane and the working end is a tamper evident needle.
5. A microfluidic device having a lancing device according to any one of claims 1 to 4.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910649387.6A CN110239804B (en) | 2019-07-17 | 2019-07-17 | Piercing device and microfluidic device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910649387.6A CN110239804B (en) | 2019-07-17 | 2019-07-17 | Piercing device and microfluidic device |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN110239804A CN110239804A (en) | 2019-09-17 |
| CN110239804B true CN110239804B (en) | 2024-05-24 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN201910649387.6A Active CN110239804B (en) | 2019-07-17 | 2019-07-17 | Piercing device and microfluidic device |
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| CN (1) | CN110239804B (en) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111187713B (en) * | 2020-02-21 | 2020-11-27 | 厦门大学 | Micro-fluidic chip's puncture device and micro-fluidic chip detecting system |
| CN111187714B (en) * | 2020-02-21 | 2021-03-05 | 厦门大学 | Micro-fluidic chip assembly and micro-fluidic chip detection system |
| CN114100715A (en) * | 2021-11-22 | 2022-03-01 | 江苏液滴逻辑生物技术有限公司 | Sample injection mode for digital micro-fluidic chip |
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| CN207157890U (en) * | 2017-09-05 | 2018-03-30 | 源野茶香（广州）饮料食品有限公司 | Bottle cap and bottle |
| CN208677063U (en) * | 2018-03-29 | 2019-04-02 | 厦门维拓科力智能技术有限公司 | A kind of lancing device applied to tea-drinking machine |
| CN210213018U (en) * | 2019-07-17 | 2020-03-31 | 东莞博识生物科技有限公司 | Piercing device and microfluidic device |
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| CN110239804A (en) | 2019-09-17 |
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