CN110152194A - A kind of radio frequency heating ultrasound hyperthermia system and its control method - Google Patents
A kind of radio frequency heating ultrasound hyperthermia system and its control method Download PDFInfo
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- CN110152194A CN110152194A CN201910361995.7A CN201910361995A CN110152194A CN 110152194 A CN110152194 A CN 110152194A CN 201910361995 A CN201910361995 A CN 201910361995A CN 110152194 A CN110152194 A CN 110152194A
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- A61N5/00—Radiation therapy
- A61N5/01—Devices for producing movement of radiation source during therapy
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- G05D—SYSTEMS FOR CONTROLLING OR REGULATING NON-ELECTRIC VARIABLES
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- G05D23/19—Control of temperature characterised by the use of electric means
- G05D23/30—Automatic controllers with an auxiliary heating device affecting the sensing element, e.g. for anticipating change of temperature
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Abstract
The present invention relates to oncotherapy technical fields, more particularly to a kind of radio frequency heating ultrasound hyperthermia system and its control method, including radio heater, controller, isolation circuit, driving circuit, temperature-measuring module, temperature indicating device and control panel, temperature-measuring module detection human body is heated portion faces temperature, control panel includes the device for set temperature and the switch for start stop apparatus, controller is connect by isolation circuit with driving circuit, and driving circuit is connect with radio heater.Controller executes following steps: A) receive desired temperature；B difference value and change rate) are obtained；C fuzzy control signal) is generated；D) circulation executes A to C.Patient body-surface temperature is fed back by temperature-measuring module, dynamic controls the rate of heat addition of radio heater, improves temperature controlled accuracy.Beneficial effects of the present invention: by FUZZY ALGORITHMS FOR CONTROL, temperature controlled accuracy is improved.
Description
Technical field
The present invention relates to tumor treatment equipment technical fields, and in particular to a kind of radio frequency heating ultrasound hyperthermia system and its control
Method processed.
Background technique
It is taken the photograph obtained in a large amount of data and experiment the results show that being in about higher by 4 than human body temperature in research object
Family name's degree is in 8 degrees Celsius, and in the case where continuously effective carries out heat effect, after general 20min, the cancer cell tissue of research object has extremely
The sign died, only activity receives negative effect to the cell of tumour being attached in normal tissue.In cancer treatment, this grinds
Study carefully result and low cost and positive therapeutic effect is provided to many patients.Radio frequency heating have temperature-controllable, penetrability and
Volume-heated feature, thus be very suitable to apply in the treatment of tumour.
Radio frequency heat treatment concentrates in high frequency (HF) when referring to wave frequency lower than 100MHz.There are two types of high-frequency heating sides
Method is capacitor heating and induction heating respectively.Wherein, one between the capacitor heating plate of human body and RF radio frequency is acted on
A or multiple capacitors, the voltage between electrode or most of bilinearity electrodes are inserted into tissue and RF voltage.Near-induction side
The heating induction coil of formula is placed on human body surface, and by rf wave electric current, human body sensing is made to add thermogenetic radio frequency electrical
Stream, vortex induction vortex inject metallic conductor or ferromagnetic material to enhance inside of human body energy, while also in normal gap in vivo
Material.Both heating means based on radio-frequency technique are widely used, and are used equally in human body deep or shallow-layer tumor thermotherapy
Fat deposit.This technology is since there is also resistance for organism, so can also generate loss.Therefore pass through tune in the case where ignoring this factor
Whole duty ratio carrys out the heating power of medium between control panel.But current RF thermotherapeutic equipment has ignored patient temperature factor to temperature
The influence of control causes heating and temperature control effect undesirable.Thus need to develop a kind of radio frequency heating of temperature precise control
Ultrasound hyperthermia system.
Such as Chinese patent CN1522672A, publication date on August 25th, 2004, a kind of stereotaxis for treating people's in-vivo tumour
Ultrasound hyperthermia system, belongs to hyperthermia equipment in Medical Instruments, and device movable machine frame and its is added by 3 D positioning equipment
Heat source, therapeutic bed composition, characterized in that utilize three bone marks of the patient's body surface, and install laser localized light comparing respectively, make three
Laser beam focuses to form hot spot in locating rack top plate, determines the fixation position of patient and 3 D positioning equipment, as basic point, weight
Multiple positioning, mobile simulator locating frame to patient's lesion top, Mobility Center analogue probe to patient's lesion body surface projection point determine
To the straight line on line position of lesion isocenter point, the laser beam that tips of probes laser localized light comparing issues can be guided accurately to be added probe
Heat source can be widely applied to the treatment of various entity tumors to lesion.But it is not quasi- enough that it not can solve the control of heating source temperature
True problem.
Summary of the invention
The technical problem to be solved by the present invention is the technology of current radio frequency tumour thermal therapy system temperature control inaccuracy is asked
Topic.Propose a kind of radio frequency heating ultrasound hyperthermia system and its control method with temperature feedback control.
In order to solve the above technical problems, the technical solution used in the present invention are as follows: a kind of radio frequency heating ultrasound hyperthermia system,
It further include controller, isolation circuit, driving circuit, temperature-measuring module, temperature indicating device and control including radio heater
Panel, temperature-measuring module detection human body are heated portion faces temperature, the temperature indicating device, control panel and temperature
Measurement module is connect with controller, and control panel includes the device for set temperature and the switch for start stop apparatus,
Controller is connect by isolation circuit with driving circuit, and driving circuit is connect with radio heater；The controller executes following
Step: A) from control panel receive desired temperature；B the difference value for) comparing temperature-measuring module and desired temperature, obtains temperature
Spend the change rate of measurement module measured value；C fuzzy control signal) is generated according to difference value and change rate, by Temperature Fuzzy Control
Signal issues driving circuit execution；D) circulation executes step A to C.Patient body-surface temperature feedback is arrived by temperature-measuring module
Controller generates control signal by controller dynamic, controls the rate of heat addition of radio heater, and it is temperature controlled accurate to improve
Property.
Preferably, the temperature-measuring module includes temperature sensitive element, AD conversion unit, low temperature trigger, height
Warm trigger, cache memory, CRC generator, memory, MCU, configuration register and serial communication unit, temperature spirit
Quick element is connect by AD conversion unit with cache memory, low temperature trigger, high temperature trigger, CRC generator with
And configuration register is connect with cache memory, temperature sensitive element, low temperature trigger and high temperature trigger with
It is heated human body connection, detection is heated human body temperature, and detected person's body region temperature is lower than low when lower limit temperature
Warm trigger output signal, high temperature trigger output signal when detected person's body region temperature is higher than ceiling temperature, cache
Memory, memory and serial communication unit are connect with MCU, and CRC generator and configuration register are periodically to high speed
Buffer memory input content, MCU periodic reading cache memory are simultaneously stored in memory, serial communication unit with
Controller communication connection.It is digital signal that temperature sensitive element, which will measure temperature inversion by AD conversion unit, is then stored
In cache memory, corresponding content is input in cache memory by CRC generator and configuration register, by
MCU is disposably read, and can accelerate the speed of temperature measurement.
Preferably, the isolation circuit includes light emitting diode D21, phototriode Q11, current-limiting resistance RL and direct current
Power Vcc 1, the light emitting diode D21 anode are connect with controller output end, light emitting diode D21 minus earth, and photosensitive three
Pole pipe Q11 base stage and light emitting diode D21 optical coupling, phototriode Q11 collector are connect with DC power supply Vcc1, and photosensitive three
Pole pipe Q11 emitter is grounded through current-limiting resistance RL, and phototriode Q11 emitter is connect with driving circuit input terminal.By every
Can protect control circuit not from circuit is influenced by the surge voltage that radio heater generates, and protects control circuit.
Preferably, the driving circuit includes metal-oxide-semiconductor M1, metal-oxide-semiconductor M2, metal-oxide-semiconductor M3, metal-oxide-semiconductor M4, diode D1, two
Pole pipe D2, diode D3, diode D4, resistance R1, resistance R2, resistance R3, resistance R4, zener diode D5, zener diode
D6, zener diode D7, zener diode D8 and power Vcc, metal-oxide-semiconductor M1 grid are made as control terminal DG1, metal-oxide-semiconductor M2 grid
For control terminal DG2, metal-oxide-semiconductor M3 grid as control terminal DG3, metal-oxide-semiconductor M4 grid as control terminal DG4, metal-oxide-semiconductor M1 drain electrode and
Metal-oxide-semiconductor M2 drain electrode is connect with power Vcc, and metal-oxide-semiconductor M1 source electrode and metal-oxide-semiconductor M3 drain electrode connect, metal-oxide-semiconductor M2 source electrode and metal-oxide-semiconductor M4
Drain electrode connection, metal-oxide-semiconductor M3 and metal-oxide-semiconductor M4 source grounding, diode D1 and diode D2 cathode connect with power Vcc, and two
Pole pipe D1 anode is connect with metal-oxide-semiconductor M1 source electrode, and diode D2 anode is connect with metal-oxide-semiconductor M2 source electrode, diode D3 anode and metal-oxide-semiconductor
The connection of M3 source electrode, diode D4 anode are connect with metal-oxide-semiconductor M4 source electrode, and metal-oxide-semiconductor M1 source electrode is connect with radio heater first end,
Metal-oxide-semiconductor M2 source electrode is connect with radio heater second end, zener diode D5 cathode and resistance R1 first end with metal-oxide-semiconductor M1
Grid connection, zener diode D5 anode and resistance R1 second end be grounded, zener diode D6 cathode and resistance R2 the
One end is connect with metal-oxide-semiconductor M2 grid, and zener diode D6 anode and resistance R2 second end are grounded, zener diode D7 yin
Pole and resistance R3 first end are connect with metal-oxide-semiconductor M3 grid, and zener diode D7 anode and resistance R3 second end are grounded,
Zener diode D8 cathode and resistance R4 first end are connect with metal-oxide-semiconductor M4 grid, zener diode D8 anode and resistance
R4 second end is grounded, and control terminal DG1 and DG4 input driving square wave, driving square wave negate rear input control end DG1 and DG4.
The working method of control circuit are as follows: when control terminal DG1 and DG4 input high level, control terminal DG2 and DG3 input are low
When level, metal-oxide-semiconductor M1 and M4 conducting, metal-oxide-semiconductor M2 and M3 cut-off, radio heater obtains forward current, as control terminal DG1 and
DG4 input low level, when control terminal DG2 and DG3 input high level, metal-oxide-semiconductor M1 and M4 cut-off, metal-oxide-semiconductor M2 and M3 conducting, radio frequency
Heater obtains reverse current, to obtain high-frequency ac current, so that radio heater is generated radio frequency, for heating.Pass through tune
The duty ratio of whole driving square wave, the power of adjustable radio frequency, so as to adjust the rate of heat addition.
Preferably, further including that 4 road signals follow circuit, the control signal that the driving circuit generates inputs 4 tunnels respectively
Signal follows circuit, and 4 road signal follows circuit to connect respectively with control terminal DG1, DG2, DG3 and DG4, and the signal follows
Circuit includes high-speed photoelectric coupler IC1, resistance R9, resistance R13, resistance R14, power supply VCC2, triode Q1 and triode Q2,
The LED+ pin of high-speed photoelectric coupler IC1 is connect by resistance R9 with power supply VCC2, and the LED- of high-speed photoelectric coupler IC1 draws
Foot is connect with control signal, and the end VCC and the end EN of high-speed photoelectric coupler IC1 is connect with power supply VCC2, high speed optoelectronic coupling
The OUT terminal of device IC1 is connect with resistance R13 second end and resistance R14 first end, and resistance R13 first end is connect with power supply VCC2, electricity
Resistance R14 second end is connect with triode Q1 base stage and triode Q2 base stage, and triode Q1 collector is connect with power supply VCC2, three poles
Pipe Q1 emitter is connect with triode Q2 emitter, triode Q1 emitter as signal output end and with control terminal DG1, DG2,
DG3 or DG4 connection, triode Q2 collector and high-speed photoelectric coupler IC1 ground terminal are grounded.Signal follows circuit can
Amendment has been amplified to control signal, has improved temperature controlled accuracy.
Preferably, further including at least two voltage regulator circuits, voltage regulator circuit includes three terminal regulator U4, resistance R31, resistance
R32, capacitor C7, capacitor C8 and diode D37, capacitor C7 first end are connect with DC power supply Vcc3, capacitor C7 second end ground connection,
Three terminal regulator U4 input terminal is connect with capacitor C7 first end, and three terminal regulator ground terminal is connect with resistance R32 second end, resistance
R32 first end ground connection, three terminal regulator U4 output end are connect with resistance R31 first end and capacitor C8 first end, resistance R31 second
End is connect with resistance R32 second end, and capacitor C8 second end is grounded, the capacitor C8 first ends of at least two voltage regulator circuits respectively as
DC power supply Vcc and DC power supply Vcc2, and circuit connection is followed with driving circuit and signal respectively.
A kind of control method of radio frequency heating ultrasound hyperthermia system is suitable for a kind of radio frequency heating tumor thermotherapy as the aforementioned
System, comprising the following steps: A) controller from control panel receive desired temperature；B) comparison temperature-measuring module is set with temperature
The difference value of definite value obtains the change rate of temperature-measuring module measured value；C temperature control) is generated according to difference value and change rate
Temperature control signals are issued driving circuit and executed by signal, and driving circuit generates duty ratio corresponding according to temperature control signals
Square wave is driven, radio heater is driven；D) circulation executes step A to C.
Preferably, generating the method for temperature control signals in step C the following steps are included: C1) difference value Error=
To-Tt, wherein ToFor set temperature, TtTo measure temperature, change rateTt-1Temperature, Δ T are measured for the last time
For the temperature measurement interval time；C2 Tables 1 and 2) is looked into respectively, obtains the value of fuzzy variable E and fuzzy variable RT；
The corresponding relationship of table 1 difference value Error and fuzzy variable E
The corresponding relationship of table 2 difference value Rate and fuzzy variable RT
| Rate | Rate≤-0.13 | - 0.13 < Rate≤- 0.06 | - 0.06 < Rate < 0 | Rate=0 |
| Fuzzy variable RT | NL | N | NS | 0 |
| Rate | 0 Rate≤0.06 < | 0.06 Rate≤0.13 < | 0.13 < Rate | |
| Fuzzy variable RT | PS | P | PL |
C3 it) tables look-up the value of 3 acquisition fuzzy variable R；
The corresponding relationship of table 3 temperature control signals and fuzzy variable R
C4 it) tables look-up 4 acquisition temperature control signals and its corresponding duty ratio:
Table: the corresponding relationship of 4 temperature control signals and fuzzy variable R
| Duty ratio | 0 | 5% | 10% | 15% | 20% |
| Fuzzy variable R | 0 | P0 | P1 | P2 | P3 |
| Duty ratio | 25% | 30% | 35% | 40% | |
| Fuzzy variable R | P4 | P5 | P6 | P7 |
Temperature control signals are issued, driving circuit generates the driving square wave of duty ratio corresponding.
Substantial effect of the invention is: by temperature-measuring module by patient body-surface temperature feedback to controller, by controlling
Device dynamic processed generates control signal, controls the rate of heat addition of radio heater, improves temperature controlled accuracy；Pass through Fuzzy Control
Algorithm processed further increases temperature controlled accuracy.
Detailed description of the invention
Fig. 1 is one module connection diagram of embodiment.
Fig. 2 is one temperature-measuring module structural schematic diagram of embodiment.
Fig. 3 is one isolation circuit schematic diagram of embodiment.
Fig. 4 is embodiment one drive circuit schematic diagram.
Fig. 5 is that one signal of embodiment follows circuit diagram.
Fig. 6 is one voltage regulator circuit schematic diagram of embodiment.
Fig. 7 is one control method flow diagram of embodiment.
Wherein: 100, isolation circuit, 200, controller, 300, control panel, 301, temperature indicating device, 302, temperature sets
Determine device, 303, start stop switch, 400, driving circuit, 500, radio heater, 600, temperature-measuring module, 601, memory,
602, MCU, 603, serial communication unit, 604, cache memory, 605, AD conversion unit, 606, temperature sensitive member
Part, 607, low temperature trigger, 608, high temperature trigger, 609, CRC generator, 610, configuration register, 700, human body is heated
Position.
Specific embodiment
Below by specific embodiment, and in conjunction with attached drawing, a specific embodiment of the invention is further described in detail.
Embodiment one:
A kind of radio frequency heating ultrasound hyperthermia system, as shown in Figure 1, the present embodiment include radio heater 500, include controller 200,
Isolation circuit 100, driving circuit 400, temperature-measuring module 600, temperature indicating device 301 and control panel 300, temperature measurement
Module 600 detects human body and is heated 700 surface temperature of position, temperature indicating device 301, control panel 300 and temperature measurement
Module 600 is connect with controller 200, and control panel 300 includes the temperature setting device 302 for set temperature and is used for
The start stop switch 303 of start stop apparatus, controller 200 are connect by isolation circuit 100 with driving circuit 400, driving circuit 400 and
Radio heater 500 connects.As shown in Fig. 2, temperature-measuring module 600 includes temperature sensitive element 606, AD conversion unit
605, low temperature trigger 607, high temperature trigger 608, cache memory 604, CRC generator 609, memory 601,
MCU602, configuration register 610 and serial communication unit 603, temperature sensitive element 606 pass through AD conversion unit 605 and height
Fast buffer memory 604 connects, low temperature trigger 607, high temperature trigger 608, CRC generator 609 and configuration register 610
Connect with cache memory 604, temperature sensitive element 606, low temperature trigger 607 and high temperature trigger 608 with
It is heated human body connection, detection is heated human body temperature, and detected person's body region temperature is lower than 10 DEG C of lower limit temperature
When 607 output signal of low temperature trigger, high temperature trigger 608 exports when detected person's body region temperature is higher than 68 DEG C of ceiling temperature
Signal, cache memory 604, memory 601 and serial communication unit 603 are connect with MCU602, CRC generator
609 and configuration register 610 periodically to 604 input content of cache memory, MCU602 periodic reading high speed is slow
It deposits memory 604 and is stored in memory 601, serial communication unit 603 and controller 200 communicate to connect.Temperature sensitive member
It is digital signal that part 606, which will measure temperature inversion by AD conversion unit 605, is then stored in cache memory 604
In, corresponding content is input in cache memory 604 by CRC generator 609 and configuration register 610, by MCU602 mono-
Secondary property is read, and can accelerate the speed of temperature measurement.As shown in figure 3,100 isolation circuit of isolation circuit includes light emitting diode
D21, phototriode Q11, current-limiting resistance RL and DC power supply Vcc1, light emitting diode D21 anode and 200 output end of controller
Connection, light emitting diode D21 minus earth, phototriode Q11 base stage and light emitting diode D21 optical coupling, phototriode
Q11 collector is connect with DC power supply Vcc1, and phototriode Q11 emitter is grounded through current-limiting resistance RL, phototriode Q11
Emitter is connect with 400 input terminal of driving circuit.It can protect control circuit not by radio heater by isolation circuit 100
500 surge voltages generated influence, and protect control circuit.
As shown in figure 4, driving circuit 400 includes metal-oxide-semiconductor M1, metal-oxide-semiconductor M2, metal-oxide-semiconductor M3, metal-oxide-semiconductor M4, diode D1, two
Pole pipe D2, diode D3, diode D4, resistance R1, resistance R2, resistance R3, resistance R4, zener diode D5, zener diode
D6, zener diode D7, zener diode D8 and power Vcc, metal-oxide-semiconductor M1 grid are made as control terminal DG1, metal-oxide-semiconductor M2 grid
For control terminal DG2, metal-oxide-semiconductor M3 grid as control terminal DG3, metal-oxide-semiconductor M4 grid as control terminal DG4, metal-oxide-semiconductor M1 drain electrode and
Metal-oxide-semiconductor M2 drain electrode is connect with power Vcc, and metal-oxide-semiconductor M1 source electrode and metal-oxide-semiconductor M3 drain electrode connect, metal-oxide-semiconductor M2 source electrode and metal-oxide-semiconductor M4
Drain electrode connection, metal-oxide-semiconductor M3 and metal-oxide-semiconductor M4 source grounding, diode D1 and diode D2 cathode connect with power Vcc, and two
Pole pipe D1 anode is connect with metal-oxide-semiconductor M1 source electrode, and diode D2 anode is connect with metal-oxide-semiconductor M2 source electrode, diode D3 anode and metal-oxide-semiconductor
The connection of M3 source electrode, diode D4 anode are connect with metal-oxide-semiconductor M4 source electrode, and metal-oxide-semiconductor M1 source electrode and 500 first end of radio heater connect
Connect, metal-oxide-semiconductor M2 source electrode is connect with 500 second end of radio heater, zener diode D5 cathode and resistance R1 first end with
The connection of metal-oxide-semiconductor M1 grid, zener diode D5 anode and resistance R1 second end are grounded, zener diode D6 cathode and electricity
Resistance R2 first end is connect with metal-oxide-semiconductor M2 grid, and zener diode D6 anode and resistance R2 second end are grounded, two pole of pressure stabilizing
Pipe D7 cathode and resistance R3 first end are connect with metal-oxide-semiconductor M3 grid, zener diode D7 anode and resistance R3 second end
Be grounded, zener diode D8 cathode and resistance R4 first end are connect with metal-oxide-semiconductor M4 grid, zener diode D8 anode with
And resistance R4 second end is grounded, control terminal DG1 and DG4 input driving square wave, driving square wave negate rear input control end DG1 and
DG4.The working method of control circuit are as follows: when control terminal DG1 and DG4 input high level, control terminal DG2 and DG3 input low level
When, metal-oxide-semiconductor M1 and M4 conducting, metal-oxide-semiconductor M2 and M3 cut-off, radio heater 500 obtains forward current, as control terminal DG1 and DG4
Input low level, when control terminal DG2 and DG3 input high level, metal-oxide-semiconductor M1 and M4 cut-off, metal-oxide-semiconductor M2 and M3 conducting, radio frequency adds
Hot device 500 obtains reverse current, to obtain high-frequency ac current, so that radio heater 500 is generated radio frequency, for heating.It is logical
Cross the duty ratio of adjustment driving square wave, the power of adjustable radio frequency, so as to adjust the rate of heat addition.
The control signal that driving circuit 400 generates inputs 4 road signals respectively and follows circuit, and 4 road signals follow circuit to distinguish
It is connect with control terminal DG1, DG2, DG3 and DG4, as shown in figure 5, it includes high-speed photoelectric coupler IC1, resistance that signal, which follows circuit,
The LED+ pin of R9, resistance R13, resistance R14, power supply VCC2, triode Q1 and triode Q2, high-speed photoelectric coupler IC1 are logical
It crosses resistance R9 to connect with power supply VCC2, the LED- pin of high-speed photoelectric coupler IC1 is connect with control signal, high speed optoelectronic coupling
The end VCC and the end EN of device IC1 is connect with power supply VCC2, the OUT terminal of high-speed photoelectric coupler IC1 and resistance R13 second end and
The connection of resistance R14 first end, resistance R13 first end are connect with power supply VCC2, resistance R14 second end and triode Q1 base stage and three
The connection of pole pipe Q2 base stage, triode Q1 collector are connect with power supply VCC2, and triode Q1 emitter and triode Q2 emitter connect
It connects, triode Q1 emitter is connect as signal output end and with control terminal DG1, DG2, DG3 or DG4, triode Q2 collector
And high-speed photoelectric coupler IC1 ground terminal is grounded.Signal follows circuit that can amplify amendment to control signal, mentions
The accuracy of high-temperature control.
As shown in fig. 6, voltage regulator circuit includes three terminal regulator U4, resistance R31, resistance R32, capacitor C7, capacitor C8 and two
Pole pipe D37, capacitor C7 first end are connect with DC power supply Vcc3, capacitor C7 second end ground connection, three terminal regulator U4 input terminal with
The connection of capacitor C7 first end, three terminal regulator ground terminal are connect with resistance R32 second end, resistance R32 first end ground connection, and three ends are steady
Depressor U4 output end is connect with resistance R31 first end and capacitor C8 first end, and resistance R31 second end and resistance R32 second end connect
It connects, capacitor C8 second end ground connection, the capacitor C8 first end of at least two voltage regulator circuits is respectively as DC power supply Vcc and direct current
Power Vcc 2, and circuit connection is followed with driving circuit and signal respectively.
A kind of control method of radio frequency heating ultrasound hyperthermia system is suitable for a kind of radio frequency heating tumor thermotherapy as the aforementioned
System, as shown in fig. 7, comprises following steps: A) controller 200 from control panel 300 receive desired temperature；B temperature) is compared
The difference value of measurement module 600 and desired temperature obtains the change rate of 600 measured value of temperature-measuring module；C) according to difference
Value and change rate generate temperature control signals, and temperature control signals are issued driving circuit 400 and are executed, 400 basis of driving circuit
Temperature control signals generate the driving square wave of duty ratio corresponding, drive radio heater 500；D) circulation executes step A to C.
The method of temperature control signals is generated in step C the following steps are included: C1) difference value Error=To-Tt, wherein To
For set temperature, TtTo measure temperature, change rateTt-1Temperature is measured for the last time, Δ T is temperature measurement
Interval time；C2 Tables 1 and 2) is looked into respectively, obtains the value of fuzzy variable E and fuzzy variable RT；
The corresponding relationship of table 1 difference value Error and fuzzy variable E
The corresponding relationship of table 2 difference value Rate and fuzzy variable RT
C3 it) tables look-up the value of 3 acquisition fuzzy variable R；
The corresponding relationship of table 3 temperature control signals and fuzzy variable R
C4 it) tables look-up 4 acquisition temperature control signals and its corresponding duty ratio:
Table: the corresponding relationship of 4 temperature control signals and fuzzy variable R
| Duty ratio | 0 | 5% | 10% | 15% | 20% |
| Fuzzy variable R | 0 | P0 | P1 | P2 | P3 |
| Duty ratio | 25% | 30% | 35% | 40% | |
| Fuzzy variable R | P4 | P5 | P6 | P7 |
Temperature control signals are issued, driving circuit 400 generates the driving square wave of duty ratio corresponding.
Above-mentioned embodiment is only a preferred solution of the present invention, not the present invention is made in any form
Limitation, there are also other variations and modifications on the premise of not exceeding the technical scheme recorded in the claims.
Claims (8)
1. a kind of radio frequency heating ultrasound hyperthermia system, including radio heater, which is characterized in that
It further include controller, isolation circuit, driving circuit, temperature-measuring module, temperature indicating device and control panel, temperature is surveyed
Amount module detection human body is heated portion faces temperature, and the temperature indicating device, control panel and temperature-measuring module are equal
It is connect with controller, control panel includes the device for set temperature and the switch for start stop apparatus, and controller passes through
Isolation circuit is connect with driving circuit, and driving circuit is connect with radio heater.
2. a kind of radio frequency heating ultrasound hyperthermia system according to claim 1, which is characterized in that
The temperature-measuring module includes temperature sensitive element, AD conversion unit, low temperature trigger, high temperature trigger, high speed
Buffer memory, CRC generator, memory, MCU, configuration register and serial communication unit, temperature sensitive element pass through modulus
Converting unit is connect with cache memory, and low temperature trigger, high temperature trigger, CRC generator and configuration register are equal
Connect with cache memory, temperature sensitive element, low temperature trigger and high temperature trigger be heated human body
Connection, detection are heated human body temperature, low temperature trigger output letter when detected person's body region temperature is lower than lower limit temperature
Number, detected person's body region temperature be higher than ceiling temperature when high temperature trigger output signal, cache memory, memory with
And serial communication unit is connect with MCU, CRC generator and configuration register are periodically into cache memory input
Hold, MCU periodic reading cache memory is simultaneously stored in memory, and serial communication unit and controller communicate to connect.
3. a kind of radio frequency heating ultrasound hyperthermia system according to claim 1, which is characterized in that
The isolation circuit includes light emitting diode D21, phototriode Q11, current-limiting resistance RL and DC power supply Vcc1, described
Light emitting diode D21 anode is connect with controller output end, light emitting diode D21 minus earth, phototriode Q11 base stage with
Light emitting diode D21 optical coupling, phototriode Q11 collector are connect with DC power supply Vcc1, phototriode Q11 emitter
It is grounded through current-limiting resistance RL, phototriode Q11 emitter is connect with driving circuit input terminal.
4. a kind of radio frequency heating ultrasound hyperthermia system according to claim 1, which is characterized in that
The driving circuit includes metal-oxide-semiconductor M1, metal-oxide-semiconductor M2, metal-oxide-semiconductor M3, metal-oxide-semiconductor M4, diode D1, diode D2, diode
D3, diode D4, resistance R1, resistance R2, resistance R3, resistance R4, zener diode D5, zener diode D6, zener diode
D7, zener diode D8 and power Vcc, metal-oxide-semiconductor M1 grid as control terminal DG1, metal-oxide-semiconductor M2 grid as control terminal DG2,
Metal-oxide-semiconductor M3 grid is as control terminal DG3, and metal-oxide-semiconductor M4 grid is as control terminal DG4, metal-oxide-semiconductor M1 drain electrode and metal-oxide-semiconductor M2 drain electrode
It is connect with power Vcc, metal-oxide-semiconductor M1 source electrode and metal-oxide-semiconductor M3 drain electrode connect, and metal-oxide-semiconductor M2 source electrode and metal-oxide-semiconductor M4 drain electrode connect, MOS
Pipe M3 and metal-oxide-semiconductor M4 source grounding, diode D1 and diode D2 cathode with power Vcc connect, diode D1 anode with
The connection of metal-oxide-semiconductor M1 source electrode, diode D2 anode are connect with metal-oxide-semiconductor M2 source electrode, and diode D3 anode is connect with metal-oxide-semiconductor M3 source electrode,
Diode D4 anode is connect with metal-oxide-semiconductor M4 source electrode, and metal-oxide-semiconductor M1 source electrode is connect with radio heater first end, metal-oxide-semiconductor M2 source electrode with
The connection of radio heater second end, zener diode D5 cathode and resistance R1 first end are connect with metal-oxide-semiconductor M1 grid, pressure stabilizing
Diode D5 anode and resistance R1 second end are grounded, and zener diode D6 cathode and resistance R2 first end are and metal-oxide-semiconductor
The connection of M2 grid, zener diode D6 anode and resistance R2 second end are grounded, zener diode D7 cathode and resistance R3
First end is connect with metal-oxide-semiconductor M3 grid, and zener diode D7 anode and resistance R3 second end are grounded, zener diode D8
Cathode and resistance R4 first end are connect with metal-oxide-semiconductor M4 grid, and zener diode D8 anode and resistance R4 second end connect
Ground, control terminal DG1 and DG4 input driving square wave, driving square wave negate rear input control end DG1 and DG4.
5. a kind of radio frequency heating ultrasound hyperthermia system according to claim 4, which is characterized in that
It further include that 4 road signals follow circuit, the control signal that the driving circuit generates inputs 4 road signals respectively and follows circuit,
4 road signal follows circuit to connect respectively with control terminal DG1, DG2, DG3 and DG4, and it includes high speed that the signal, which follows circuit,
Photoelectrical coupler IC1, resistance R9, resistance R13, resistance R14, power Vcc 2, triode Q1 and triode Q2, high speed optoelectronic coupling
The LED+ pin of device IC1 is connect by resistance R9 with power Vcc 2, the LED- pin and control signal of high-speed photoelectric coupler IC1
Connection, the end Vcc and the end EN of high-speed photoelectric coupler IC1 are connect with power Vcc 2, the OUT terminal of high-speed photoelectric coupler IC1
It is connect with resistance R13 second end and resistance R14 first end, resistance R13 first end is connect with power Vcc 2, resistance R14 second end
It is connect with triode Q1 base stage and triode Q2 base stage, triode Q1 collector is connect with power Vcc 2, triode Q1 emitter
It is connect with triode Q2 emitter, triode Q1 emitter connects as signal output end and with control terminal DG1, DG2, DG3 or DG4
It connects, triode Q2 collector and high-speed photoelectric coupler IC1 ground terminal are grounded.
6. a kind of radio frequency heating ultrasound hyperthermia system according to claim 5, which is characterized in that
It further include at least two voltage regulator circuits, voltage regulator circuit includes three terminal regulator U4, resistance R31, resistance R32, capacitor C7, electricity
Hold C8 and diode D37, capacitor C7 first end is connect with DC power supply Vcc3, capacitor C7 second end ground connection, three terminal regulator U4
Input terminal is connect with capacitor C7 first end, and three terminal regulator ground terminal is connect with resistance R32 second end, and resistance R32 first is terminated
Ground, three terminal regulator U4 output end are connect with resistance R31 first end and capacitor C8 first end, resistance R31 second end and resistance R32
Second end connection, capacitor C8 second end ground connection, the capacitor C8 first end of at least two voltage regulator circuits is respectively as DC power supply Vcc
And DC power supply Vcc2, and circuit connection is followed with driving circuit and signal respectively.
7. a kind of control method of radio frequency heating ultrasound hyperthermia system is suitable for a kind of radio frequency heating as described in claim 1
Ultrasound hyperthermia system, which is characterized in that
The following steps are included:
A) controller receives desired temperature from the control panel；
B the difference value for) comparing the temperature-measuring module measured value and desired temperature, obtains temperature-measuring module measured value
Change rate；
C temperature control signals) are generated according to difference value and change rate, temperature control signals are issued into the driving circuit and are executed,
Driving circuit generates the driving square wave of duty ratio corresponding, drives the radio heater according to temperature control signals；
D) circulation executes step A to C.
8. a kind of control method of radio frequency heating ultrasound hyperthermia system according to claim 7, which is characterized in that
In step C generate temperature control signals method the following steps are included:
C1) difference value Error=To-Tt, wherein ToFor set temperature, TtTo measure temperature, change rateTt-1
Temperature is measured for the last time, Δ T is the temperature measurement interval time；
C2 Tables 1 and 2) is looked into respectively, obtains the value of fuzzy variable E and fuzzy variable RT；
The corresponding relationship of table 1 difference value Error and fuzzy variable E
The corresponding relationship of table 2 difference value Rate and fuzzy variable RT
C3 it) tables look-up the value of 3 acquisition fuzzy variable R；
The corresponding relationship of table 3 temperature control signals and fuzzy variable R
C4 it) tables look-up 4 acquisition temperature control signals and its corresponding duty ratio:
Table: the corresponding relationship of 4 temperature control signals and fuzzy variable R
Temperature control signals are issued, driving circuit generates the driving square wave of duty ratio corresponding.
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